Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionolfactory receptor activity

OR51S1 OR52K1 OR4Q2 OR51M1 OR52H1 OR4K1 OR4Q3 OR52K2 OR52J3 OR2W6P OR52E2

5.76e-064319411GO:0004984
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR51S1 OR52K1 OR4Q2 GPR142 OR51M1 OR52H1 OR4K1 OR4Q3 GPRC6A OR52K2 NPFFR1 GPR176 OR52J3 OR2W6P OR52E2

1.54e-058849415GO:0004930
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DYNC2H1 DNAH7 DNAH11

7.83e-0518943GO:0008569
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR51S1 OR52K1 OR4Q2 GPR142 OR51M1 OR52H1 OR4K1 PKD1 OR4Q3 GPRC6A ACVR1 OR52K2 NPFFR1 GPR176 OR52J3 OR2W6P OR52E2

1.74e-0413539417GO:0004888
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DYNC2H1 DNAH7 DNAH11

3.04e-0428943GO:0051959
GeneOntologyMolecularFunctiondynein intermediate chain binding

DYNC2H1 DNAH7 DNAH11

6.99e-0437943GO:0045505
GeneOntologyMolecularFunctiontRNA binding

PTCD1 QTRT2 TRMT1L XPOT

7.61e-0487944GO:0000049
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR51S1 OR52K1 OR4Q2 OR51M1 OR52H1 OR4K1 OR4Q3 OR52K2 OR52J3 OR2W6P OR52E2

3.91e-064329311GO:0050911
GeneOntologyBiologicalProcesscytosolic transport

TBC1D10C TBC1D10B GBF1 PPFIA2 VPS13A HEATR5A EHD3

5.25e-06150937GO:0016482
GeneOntologyBiologicalProcesssensory perception of smell

OR51S1 OR52K1 OR4Q2 OR51M1 OR52H1 OR4K1 OR4Q3 OR52K2 OR52J3 OR2W6P OR52E2

7.85e-064659311GO:0007608
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR51S1 OR52K1 OR4Q2 OR51M1 OR52H1 OR4K1 OR4Q3 OR52K2 OR52J3 OR2W6P OR52E2

1.16e-054859311GO:0050907
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR51S1 OR52K1 OR4Q2 OR51M1 OR52H1 OR4K1 OR4Q3 GJA10 OR52K2 OR52J3 OR2W6P OR52E2

1.18e-055829312GO:0050906
GeneOntologyBiologicalProcessdetection of stimulus

OR51S1 OR52K1 OR4Q2 OR51M1 OR52H1 OR4K1 PKD1 OR4Q3 GJA10 OR52K2 OR52J3 OR2W6P OR52E2

2.09e-057229313GO:0051606
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR51S1 OR52K1 OR4Q2 OR51M1 OR52H1 OR4K1 OR4Q3 OR52K2 OR52J3 OR2W6P OR52E2

2.38e-055249311GO:0009593
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR51S1 OR52K1 OR4Q2 OR51M1 OR52H1 OR4K1 OR4Q3 OR52K2 OR52J3 OR2W6P OR52E2

3.53e-055479311GO:0007606
GeneOntologyBiologicalProcessretrograde transport, endosome to Golgi

TBC1D10C TBC1D10B GBF1 HEATR5A EHD3

1.35e-04109935GO:0042147
GeneOntologyBiologicalProcesscilium movement

CFAP54 CATSPER1 CFAP73 DYNC2H1 VPS13A DNAH7 DNAH11

1.80e-04261937GO:0003341
GeneOntologyBiologicalProcesscilium organization

TBC1D10C TBC1D10B CFAP54 GBF1 CFAP73 DYNC2H1 RTTN DNAH7 EHD3

2.98e-04476939GO:0044782
GeneOntologyBiologicalProcesssensory perception

OR51S1 OR52K1 OR4Q2 OR51M1 OR52H1 OR4K1 OR4Q3 MGLL GJA10 EYA1 OR52K2 OR52J3 OR2W6P OR52E2

3.07e-0410729314GO:0007600
DomainARM-type_fold

URB1 GBF1 COPB1 PIK3C2A ELMO2 RTTN MROH5 CUL9 HEATR5A XPOT EFR3A

8.68e-073399211IPR016024
Domain-

COPB1 ELMO2 RTTN MROH5 CUL9 HEATR5A XPOT EFR3A

1.39e-052229281.25.10.10
DomainRb_C

RB1 RBL1

2.40e-052922PF08934
DomainDynein_heavy_chain_D4_dom

DYNC2H1 DNAH7 DNAH11

4.05e-0514923IPR024317
DomainDynein_HC_stalk

DYNC2H1 DNAH7 DNAH11

4.05e-0514923IPR024743
DomainDynein_heavy_dom-2

DYNC2H1 DNAH7 DNAH11

4.05e-0514923IPR013602
DomainDHC_N2

DYNC2H1 DNAH7 DNAH11

4.05e-0514923PF08393
DomainMT

DYNC2H1 DNAH7 DNAH11

4.05e-0514923PF12777
DomainAAA_8

DYNC2H1 DNAH7 DNAH11

4.05e-0514923PF12780
DomainDHC_fam

DYNC2H1 DNAH7 DNAH11

5.04e-0515923IPR026983
DomainDynein_heavy_dom

DYNC2H1 DNAH7 DNAH11

5.04e-0515923IPR004273
DomainDynein_heavy

DYNC2H1 DNAH7 DNAH11

5.04e-0515923PF03028
DomainARM-like

COPB1 ELMO2 RTTN MROH5 CUL9 HEATR5A XPOT EFR3A

5.61e-05270928IPR011989
DomainRB_A

RB1 RBL1

7.18e-053922IPR002720
DomainDUF3452

RB1 RBL1

7.18e-053922PF11934
DomainRB_B

RB1 RBL1

7.18e-053922IPR002719
DomainRB_A

RB1 RBL1

7.18e-053922PF01858
DomainRB_B

RB1 RBL1

7.18e-053922PF01857
DomainRB_C

RB1 RBL1

7.18e-053922IPR015030
DomainRB_fam

RB1 RBL1

7.18e-053922IPR028309
DomainDUF3452

RB1 RBL1

7.18e-053922SM01367
DomainRb_C

RB1 RBL1

7.18e-053922SM01369
DomainRB_A

RB1 RBL1

7.18e-053922SM01368
DomainRB_N

RB1 RBL1

7.18e-053922IPR024599
DomainGPCR_Rhodpsn_7TM

OR51S1 OR52K1 GPR142 OR51M1 OR52H1 OR4K1 OR4Q3 OR52K2 NPFFR1 GPR176 OR52J3 OR52E2

1.08e-046709212IPR017452
Domain7tm_1

OR51S1 OR52K1 GPR142 OR51M1 OR52H1 OR4K1 OR4Q3 OR52K2 NPFFR1 GPR176 OR52J3 OR52E2

1.19e-046779212PF00001
DomainG_PROTEIN_RECEP_F1_1

OR51S1 OR52K1 GPR142 OR51M1 OR52H1 OR4K1 OR4Q3 OR52K2 NPFFR1 GPR176 OR52J3 OR52E2

1.33e-046859212PS00237
DomainOlfact_rcpt

OR51S1 OR52K1 OR51M1 OR52H1 OR4K1 OR4Q3 OR52K2 OR52J3 OR52E2

1.37e-04393929IPR000725
Domain-

GTF2IRD2B GTF2IRD2

1.43e-0449223.90.1460.10
DomainGTF2I

GTF2IRD2B GTF2IRD2

1.43e-044922PS51139
DomainGTF2I

GTF2IRD2B GTF2IRD2

1.43e-044922PF02946
DomainGTF2I

GTF2IRD2B GTF2IRD2

1.43e-044922IPR004212
DomainG_PROTEIN_RECEP_F1_2

OR51S1 OR52K1 GPR142 OR51M1 OR52H1 OR4K1 OR4Q3 OR52K2 NPFFR1 GPR176 OR52J3 OR52E2

1.44e-046919212PS50262
DomainGPCR_Rhodpsn

OR51S1 OR52K1 GPR142 OR51M1 OR52H1 OR4K1 OR4Q3 OR52K2 NPFFR1 GPR176 OR52J3 OR52E2

1.46e-046929212IPR000276
DomainDHC_N1

DYNC2H1 DNAH11

6.59e-048922PF08385
DomainDynein_heavy_dom-1

DYNC2H1 DNAH11

6.59e-048922IPR013594
DomainEF-hand_4

ITSN1 EHD3

1.05e-0310922PF12763
DomainEH

ITSN1 EHD3

1.28e-0311922PS50031
DomainEH

ITSN1 EHD3

1.28e-0311922SM00027
DomainEH_dom

ITSN1 EHD3

1.28e-0311922IPR000261
DomainTBC

TBC1D10C TBC1D10B TBC1D4

1.81e-0349923SM00164
DomainATPase_dyneun-rel_AAA

DYNC2H1 DNAH11

2.10e-0314922IPR011704
DomainAAA_5

DYNC2H1 DNAH11

2.10e-0314922PF07728
DomainRabGAP-TBC

TBC1D10C TBC1D10B TBC1D4

2.27e-0353923PF00566
DomainTBC_RABGAP

TBC1D10C TBC1D10B TBC1D4

2.52e-0355923PS50086
DomainRab-GTPase-TBC_dom

TBC1D10C TBC1D10B TBC1D4

2.52e-0355923IPR000195
DomainChannel_four-helix_dom

CATSPER1 KCNV2 SLC9C2

2.79e-0357923IPR027359
Domain-

CATSPER1 KCNV2 SLC9C2

2.79e-03579231.20.120.350
Domain-

TBC1D10B PDE1B

5.20e-03229221.10.1300.10
DomainAAA+_ATPase

DYNC2H1 ABCF2 DNAH7 DNAH11

5.61e-03144924IPR003593
DomainAAA

DYNC2H1 ABCF2 DNAH7 DNAH11

5.61e-03144924SM00382
DomainPDEase_catalytic_dom

TBC1D10B PDE1B

5.68e-0323922IPR002073
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR51S1 OR52K1 OR4Q2 OR51M1 OR52H1 OR4K1 OR4Q3 OR52K2 OR52J3 OR52E2

4.24e-054177110M4072
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR51S1 OR52K1 OR51M1 OR52H1 OR4K1 OR4Q3 OR52K2 OR52J3 OR52E2

1.39e-04389719M14091
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR51S1 OR52K1 OR51M1 OR52H1 OR4K1 OR4Q3 OR52K2 OR52J3 OR2W6P OR52E2

3.38e-08340951011875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR51S1 OR52K1 OR51M1 OR52H1 OR4K1 OR4Q3 OR52K2 OR52J3 OR2W6P OR52E2

3.38e-08340951011802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR51S1 OR52K1 OR51M1 OR52H1 OR4K1 OR4Q3 OR52K2 OR52J3 OR2W6P OR52E2

3.67e-08343951032295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR51S1 OR52K1 OR51M1 OR52H1 OR4K1 OR4Q3 OR52K2 OR52J3 OR2W6P OR52E2

3.99e-08346951014611657
Pubmed

The human olfactory receptor gene family.

OR51S1 OR52K1 OR4Q2 OR51M1 OR52H1 OR4K1 OR4Q3 OR52K2 OR52J3 OR2W6P OR52E2

2.80e-07541951114983052
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

GBF1 DYNC2H1 ELMO2 ST7 FASTKD1 VPS13A TCIRG1 MGLL ACVR1 DOCK6 FITM2 ATP2A3 FAM8A1 XPOT

1.14e-061061951433845483
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DYNC2H1 DNAH7 DNAH11

7.03e-06149539373155
Pubmed

Hepatitis C virus induces E6AP-dependent degradation of the retinoblastoma protein.

RB1 UBE3A

7.38e-06295217907805
Pubmed

Interaction of mouse adenovirus type 1 early region 1A protein with cellular proteins pRb and p107.

RB1 RBL1

7.38e-0629528862413
Pubmed

Rb and p107 regulate preadipocyte differentiation into white versus brown fat through repression of PGC-1alpha.

RB1 RBL1

7.38e-06295216271529
Pubmed

Retinoblastoma susceptibility gene product (pRb) and p107 functionally separate the requirements for serum and anchorage in the cell cycle G1-phase.

RB1 RBL1

7.38e-06295214732703
Pubmed

Chromosomal mapping of two members of the human dynein gene family to chromosome regions 7p15 and 11q13 near the deafness loci DFNA 5 and DFNA 11.

DYNC2H1 DNAH11

7.38e-0629529325061
Pubmed

Susceptibility of pRb-deficient epidermis to chemical skin carcinogenesis is dependent on the p107 allele dosage.

RB1 RBL1

7.38e-06295218300254
Pubmed

Identification of pregnane-X receptor target genes and coactivator and corepressor binding to promoter elements in human hepatocytes.

NR1I2 CYP4F12

7.38e-06295219129222
Pubmed

Human papillomavirus type 16 E7 associates with a histone H1 kinase and with p107 through sequences necessary for transformation.

RB1 RBL1

7.38e-0629528386265
Pubmed

p107 regulates neural precursor cells in the mammalian brain.

RB1 RBL1

7.38e-06295215353549
Pubmed

p107 is a suppressor of retinoblastoma development in pRb-deficient mice.

RB1 RBL1

7.38e-0629529620848
Pubmed

A novel tumor suppressor network in squamous malignancies.

RB1 RBL1

7.38e-06295223145321
Pubmed

Rb and p107 are required for alpha cell survival, beta cell cycle control and glucagon-like peptide-1 action.

RB1 RBL1

7.38e-06295225249236
Pubmed

Reversal of terminal differentiation mediated by p107 in Rb-/- muscle cells.

RB1 RBL1

7.38e-0629528197461
Pubmed

Comparison of TFII-I gene family members deleted in Williams-Beuren syndrome.

GTF2IRD2B GTF2IRD2

7.38e-06295215388857
Pubmed

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.

AMFR COPB1 RB1 UBE3A RBL1 FITM2 GPR176 FAM8A1 PCYOX1

9.45e-0649995922810586
Pubmed

Misregulation of an Activity-Dependent Splicing Network as a Common Mechanism Underlying Autism Spectrum Disorders.

DYNC2H1 PPFIA2 ITSN1

1.56e-051895327984743
Pubmed

Retinoblastoma family proteins have distinct functions in pulmonary epithelial cells in vivo critical for suppressing cell growth and tumorigenesis.

RB1 RBL1

2.21e-05395219887614
Pubmed

Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry.

RB1 RBL1

2.21e-05395212853964
Pubmed

The retinoblastoma protein and its homolog p130 regulate the G1/S transition in pancreatic beta-cells.

RB1 RBL1

2.21e-05395219509021
Pubmed

p130/p107/p105Rb-dependent transcriptional repression during DNA-damage-induced cell-cycle exit at G2.

RB1 RBL1

2.21e-05395215827088
Pubmed

Differentiated horizontal interneurons clonally expand to form metastatic retinoblastoma in mice.

RB1 RBL1

2.21e-05395217956737
Pubmed

The retinoblastoma protein, RB, is required for gastrointestinal endocrine cells to exit the cell cycle, but not for hormone expression.

RB1 RBL1

2.21e-05395217936268
Pubmed

Retinoblastoma protein (pRb), but not p107 or p130, is required for maintenance of enterocyte quiescence and differentiation in small intestine.

RB1 RBL1

2.21e-05395218981186
Pubmed

pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes.

RB1 RBL1

2.21e-0539529192872
Pubmed

Inhibition of histone deacetylases targets the transcription regulator Id2 to attenuate cystic epithelial cell proliferation.

RB1 PKD1

2.21e-05395221900881
Pubmed

Targeting the p53 pathway in retinoblastoma with subconjunctival Nutlin-3a.

RB1 RBL1

2.21e-05395221515735
Pubmed

Oxidative stress induces protein phosphatase 2A-dependent dephosphorylation of the pocket proteins pRb, p107, and p130.

RB1 RBL1

2.21e-05395212621062
Pubmed

Regulation of RB transcription in vivo by RB family members.

RB1 RBL1

2.21e-05395220100864
Pubmed

Activation of NF-kB pathway by virus infection requires Rb expression.

RB1 RBL1

2.21e-05395219649275
Pubmed

Rb1 and Pten Co-Deletion in Osteoblast Precursor Cells Causes Rapid Lipoma Formation in Mice.

RB1 RBL1

2.21e-05395226317218
Pubmed

Unique and overlapping functions of pRb and p107 in the control of proliferation and differentiation in epidermis.

RB1 RBL1

2.21e-05395215148303
Pubmed

Targeted disruption of p107: functional overlap between p107 and Rb.

RB1 RBL1

2.21e-0539528682293
Pubmed

Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions.

RB1 RBL1

2.21e-05395211114893
Pubmed

Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization.

RB1 RBL1

2.21e-05395211114892
Pubmed

Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A-C.

TBC1D10C TBC1D10B

2.21e-05395220404108
Pubmed

Computational model explains high activity and rapid cycling of Rho GTPases within protein complexes.

COPB1 ITSN1

2.21e-05395217140284
Pubmed

A-type lamins regulate retinoblastoma protein function by promoting subnuclear localization and preventing proteasomal degradation.

RB1 RBL1

2.21e-05395215210943
Pubmed

Monoallelic but not biallelic loss of Dicer1 promotes tumorigenesis in vivo.

RB1 RBL1

2.21e-05395220019750
Pubmed

Neuronal differentiation and synaptogenesis in retinoblastoma.

RB1 RBL1

2.21e-05395217363591
Pubmed

Animal models in retinoblastoma research.

RB1 RBL1

2.21e-05395224227978
Pubmed

p107 acts as a tumor suppressor in pRb-deficient epidermis.

RB1 RBL1

2.21e-05395217932945
Pubmed

A role for the Rb family of proteins in controlling telomere length.

RB1 RBL1

2.21e-05395212379853
Pubmed

Ablating all three retinoblastoma family members in mouse lung leads to neuroendocrine tumor formation.

RB1 RBL1

2.21e-05395227966456
Pubmed

Mouse fibroblasts lacking RB1 function form spheres and undergo reprogramming to a cancer stem cell phenotype.

RB1 RBL1

2.21e-05395219341623
Pubmed

The first knockout mouse model of retinoblastoma.

RB1 RBL1

2.21e-05395215190215
Pubmed

Isolation and characterisation of GTF2IRD2, a novel fusion gene and member of the TFII-I family of transcription factors, deleted in Williams-Beuren syndrome.

GTF2IRD2B GTF2IRD2

2.21e-05395215100712
Pubmed

Retinoblastoma/p107/p130 pocket proteins: protein dynamics and interactions with target gene promoters.

RB1 RBL1

2.21e-05395219279001
Pubmed

The retinoblastoma gene family is differentially expressed during embryogenesis.

RB1 RBL1

2.21e-0539529150384
Pubmed

Cross-species genomic and epigenomic landscape of retinoblastoma.

RB1 RBL1

2.21e-05395223765217
Pubmed

Expression of the retinoblastoma family of tumor suppressors during murine embryonic orofacial development.

RB1 RBL1

2.21e-05395212627794
Pubmed

Interaction between human cyclin A and adenovirus E1A-associated p107 protein.

RB1 RBL1

2.21e-0539521532458
Pubmed

Genes in the RB pathway and their knockout in mice.

RB1 RBL1

2.21e-0539529110405
Pubmed

pRB plays an essential role in cell cycle arrest induced by DNA damage.

RB1 RBL1

2.21e-0539529751770
Pubmed

The retinoblastoma gene family in differentiation and development.

RB1 RBL1

2.21e-05395210630640
Pubmed

Changes in retinoblastoma cell adhesion associated with optic nerve invasion.

RB1 RBL1

2.21e-05395219786571
Pubmed

A critical temporal requirement for the retinoblastoma protein family during neuronal determination.

RB1 RBL1

2.21e-0539529508781
Pubmed

Unique impact of RB loss on hepatic proliferation: tumorigenic stresses uncover distinct pathways of cell cycle control.

RB1 RBL1

2.21e-05395219887370
Pubmed

Simultaneous depletion of RB, RBL1 and RBL2 affects endoderm differentiation of human embryonic stem cells.

RB1 RBL1

2.21e-05395236413521
Pubmed

Inactivating all three rb family pocket proteins is insufficient to initiate cervical cancer.

RB1 RBL1

2.21e-05395222942253
Pubmed

Pocket proteins suppress head and neck cancer.

RB1 RBL1

2.21e-05395222237625
Pubmed

Cell-specific effects of RB or RB/p107 loss on retinal development implicate an intrinsically death-resistant cell-of-origin in retinoblastoma.

RB1 RBL1

2.21e-05395215193257
Pubmed

Ras protects Rb family null fibroblasts from cell death: a role for AP-1.

RB1 RBL1

4.41e-05495214688262
Pubmed

Coexpression of normally incompatible developmental pathways in retinoblastoma genesis.

RB1 RBL1

4.41e-05495221840489
Pubmed

Hematopoietic stem cell quiescence is maintained by compound contributions of the retinoblastoma gene family.

RB1 RBL1

4.41e-05495218940733
Pubmed

Skip interacts with the retinoblastoma tumor suppressor and inhibits its transcriptional repression activity.

RB1 RBL1

4.41e-05495212466551
Pubmed

A dynamic equilibrium between CDKs and PP2A modulates phosphorylation of pRB, p107 and p130.

RB1 RBL1

4.41e-05495215467457
Pubmed

Inhibition of a G9a/DNMT network triggers immune-mediated bladder cancer regression.

RB1 RBL1

4.41e-05495231270502
Pubmed

Prohibitin, a potential tumor suppressor, interacts with RB and regulates E2F function.

RB1 RBL1

4.41e-05495210376528
Pubmed

Pten and p53 Loss in the Mouse Lung Causes Adenocarcinoma and Sarcomatoid Carcinoma.

RB1 RBL1

4.41e-05495235954335
Pubmed

The retinoblastoma family proteins bind to and activate diacylglycerol kinase zeta.

RB1 RBL1

4.41e-05495216286473
Pubmed

Disruption of BRCA1 LXCXE motif alters BRCA1 functional activity and regulation of RB family but not RB protein binding.

RB1 RBL1

4.41e-05495211521194
Pubmed

Molecular cloning and characterization of a novel retinoblastoma-binding protein.

RB1 RBL1

4.41e-0549529721205
Pubmed

High incidence of HPV-associated head and neck cancers in FA deficient mice is associated with E7's induction of DNA damage through its inactivation of pocket proteins.

RB1 RBL1

4.41e-05495224086435
Pubmed

Deacetylation of the retinoblastoma tumour suppressor protein by SIRT1.

RB1 RBL1

4.41e-05495217620057
Pubmed

TFII-I gene family during tooth development: candidate genes for tooth anomalies in Williams syndrome.

GTF2IRD2B GTF2IRD2

4.41e-05495217823943
Pubmed

Critical role of the Rb family in myoblast survival and fusion.

RB1 RBL1

4.41e-05495221423694
Pubmed

Evolution of general transcription factors.

GTF2IRD2B GTF2IRD2

4.41e-05495223229069
Pubmed

Structural and functional characterization of the HPV16 E7 protein expressed in bacteria.

RB1 RBL1

4.41e-0549528245034
Pubmed

Differential development of large-cell neuroendocrine or small-cell lung carcinoma upon inactivation of 4 tumor suppressor genes.

RB1 RBL1

4.41e-05495231611390
Pubmed

Rb and p107 are required for normal cerebellar development and granule cell survival but not for Purkinje cell persistence.

RB1 RBL1

4.41e-05495212810584
Pubmed

GTF2IRD2 from the Williams-Beuren critical region encodes a mobile-element-derived fusion protein that antagonizes the action of its related family members.

GTF2IRD2B GTF2IRD2

4.41e-05495222899722
Pubmed

A mouse model of MYCN-driven retinoblastoma reveals MYCN-independent tumor reemergence.

RB1 RBL1

4.41e-05495228165337
Pubmed

Rb deletion in mouse mammary progenitors induces luminal-B or basal-like/EMT tumor subtypes depending on p53 status.

RB1 RBL1

4.41e-05495220679727
Pubmed

Cooperation between Rb and Arf in suppressing mouse retinoblastoma.

RB1 RBL1

4.41e-05495222484813
Pubmed

Rb1/Rbl1/Vhl loss induces mouse subretinal angiomatous proliferation and hemangioblastoma.

RB1 RBL1

4.41e-05495231613797
Pubmed

Id2 is a retinoblastoma protein target and mediates signalling by Myc oncoproteins.

RB1 RBL1

4.41e-05495211034201
Pubmed

High incidence of female reproductive tract cancers in FA-deficient HPV16-transgenic mice correlates with E7's induction of DNA damage response, an activity mediated by E7's inactivation of pocket proteins.

RB1 RBL1

4.41e-05495224013229
Pubmed

Differential specificity for binding of retinoblastoma binding protein 2 to RB, p107, and TATA-binding protein.

RB1 RBL1

4.41e-0549527935440
Pubmed

B-Myb overcomes a p107-mediated cell proliferation block by interacting with an N-terminal domain of p107.

RB1 RBL1

4.41e-05495212439743
Pubmed

Negative regulation of DNA replication by the retinoblastoma protein is mediated by its association with MCM7.

RB1 RBL1

4.41e-0549529566894
Pubmed

LEK1 is a potential inhibitor of pocket protein-mediated cellular processes.

RB1 RBL1

4.41e-05495214555653
Pubmed

In vivo disruption of an Rb-E2F-Ezh2 signaling loop causes bladder cancer.

RB1 RBL1

4.41e-05495225252918
Pubmed

Haploinsufficiency of Gtf2i, a gene deleted in Williams Syndrome, leads to increases in social interactions.

GTF2IRD2B GTF2IRD2

4.41e-05495221328569
Cytoband11p15.4

OR51S1 OR52K1 OR51M1 OR52H1 OR52K2 OR52J3 OR52E2

2.14e-0720095711p15.4
CytobandEnsembl 112 genes in cytogenetic band chr11p15

OR51S1 OR52K1 COPB1 PIK3C2A OR51M1 OR52H1 OR52K2 OR52J3 OR52E2

2.75e-06564959chr11p15
Cytoband14q11.2

OR4Q2 OR4K1 OR4Q3 NGDN

5.51e-0418095414q11.2
Cytoband12q24.13

CFAP73 HECTD4

1.23e-032595212q24.13
Cytoband6q22.1

GPRC6A CALHM4

1.66e-03299526q22.1
CytobandEnsembl 112 genes in cytogenetic band chr20q13

ELMO2 UCKL1 FITM2 TOX2 TCFL5

1.89e-03422955chr20q13
Cytoband11q13.2

TBC1D10C TCIRG1

4.31e-034795211q13.2
CytobandEnsembl 112 genes in cytogenetic band chr14q11

OR4Q2 OR4K1 OR4Q3 NGDN

5.10e-03332954chr14q11
GeneFamilyOlfactory receptors, family 52

OR52K1 OR52H1 OR52K2 OR52J3 OR52E2

3.72e-0749555165
GeneFamilyDyneins, axonemal

DNAH7 DNAH11

1.20e-0317552536
GeneFamilyEF-hand domain containing

CAPN14 ITSN1 DNAH7 EHD3

4.41e-03219554863
GeneFamilyOlfactory receptors, family 4

OR4Q2 OR4K1 OR4Q3

7.10e-03129553151
GeneFamilyOlfactory receptors, family 51

OR51S1 OR51M1

7.92e-0344552164
CoexpressionGSE40685_NAIVE_CD4_TCELL_VS_TREG_DN

DIS3L2 TBC1D4 KIAA1549L UBE3A CUL9 TRMT1L TOX2

6.87e-06200927M9303
ToppCellnucseq-Epithelial-Epithelial_Airway|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CFAP54 CFAP73 DYNC2H1 EYA1 SLC9C2 DNAH7 DNAH11

1.79e-071919571c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RBL1 SH2D3C TOX2 ATP2A3 CALHM4 EHD3

1.02e-061559565d157478669b609e1f0f0a75afd0112571fc2c46
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP54 CFAP73 EYA1 SLC9C2 DNAH7 DNAH11

2.29e-06178956de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CFAP54 TBC1D4 SESN3 EYA1 DNAH7 DNAH11

2.52e-061819566a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCellAdult-Epithelial-ciliated_cell-D122|Adult / Lineage, Cell type, age group and donor

CFAP54 CFAP73 EYA1 SLC9C2 DNAH7 DNAH11

2.60e-061829567ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

CFAP54 CFAP73 EYA1 SLC9C2 DNAH7 DNAH11

2.60e-06182956fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFAP54 CFAP73 EYA1 SLC9C2 DNAH7 DNAH11

2.77e-061849565daff849625f2f41d56615569c0ed59cd733b34c
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

CFAP54 CFAP73 EYA1 SLC9C2 DNAH7 DNAH11

2.86e-0618595630f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

CFAP54 CFAP73 EYA1 SLC9C2 DNAH7 DNAH11

2.86e-0618595618a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellLPS_only-Hematopoietic_Meg-Ery-Erythroid-Erythroid|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AMFR CATSPER1 ITSN1 HECTD4 SESN3 RHAG

2.95e-06186956e5014443e9d6e25943308483e20d48b776ae5373
ToppCellLPS_only-Hematopoietic_Meg-Ery-Erythroid|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AMFR CATSPER1 ITSN1 HECTD4 SESN3 RHAG

2.95e-06186956affc246a1091e44dc85a5e237c778a7541d5a2b4
ToppCellLPS_only-Hematopoietic_Meg-Ery|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AMFR CATSPER1 ITSN1 HECTD4 SESN3 RHAG

2.95e-0618695640d1e15402fdfb3b5ae850a2070cd4b68fda3159
ToppCellEpithelial-ciliated_cell|World / Lineage, Cell type, age group and donor

CFAP54 CFAP73 EYA1 SLC9C2 DNAH7 DNAH11

3.14e-0618895661a459f3fe57e5728efc72637ff2edc2d343492b
ToppCellAdult-Epithelial-ciliated_cell-D231|Adult / Lineage, Cell type, age group and donor

CFAP54 CFAP73 EYA1 SLC9C2 DNAH7 DNAH11

3.14e-0618895634b11f72ca73153d02edcd09b38983ad1a504659
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFAP54 CFAP73 EYA1 SLC9C2 DNAH7 DNAH11

3.14e-061889562b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

CFAP54 CFAP73 EYA1 SLC9C2 DNAH7 DNAH11

3.23e-06189956a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFAP54 CFAP73 EYA1 SLC9C2 DNAH7 DNAH11

3.23e-0618995668a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCellAdult-Epithelial-ciliated_cell|Adult / Lineage, Cell type, age group and donor

CFAP54 CFAP73 EYA1 SLC9C2 DNAH7 DNAH11

3.23e-06189956b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

CFAP54 CFAP73 EYA1 SLC9C2 DNAH7 DNAH11

3.23e-0618995627329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CFAP54 CFAP73 EYA1 SLC9C2 DNAH7 DNAH11

3.44e-06191956e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CFAP54 CFAP73 EYA1 SLC9C2 DNAH7 DNAH11

3.44e-061919569d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCellNS-critical-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP54 CFAP73 DYNC2H1 LRRC49 DNAH7 DNAH11

3.76e-061949561ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

CFAP54 CFAP73 DYNC2H1 EYA1 DNAH7 DNAH11

3.87e-06195956fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellIPF-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

CFAP54 CFAP73 DYNC2H1 EYA1 DNAH7 DNAH11

3.87e-0619595621dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

CFAP54 CFAP73 DYNC2H1 EYA1 DNAH7 DNAH11

3.87e-06195956eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellControl-Neu_4|Control / 5 Neutrophil clusters in COVID-19 patients

GBF1 COPB1 FASTKD1 VPS13A TRMT1L XPOT

3.99e-06196956b8b7b54ca17a08fa775507bb22b1c7248ada8f40
ToppCellIPF-Epithelial|IPF / Disease state, Lineage and Cell class

CFAP54 CFAP73 DYNC2H1 EYA1 DNAH7 DNAH11

3.99e-0619695687d9881cfec461a5d89b688a83749b618c519485
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP54 CFAP73 DYNC2H1 SLC9C2 DNAH7 DNAH11

4.11e-0619795674a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellCOVID-19-Epithelial_cells-Airway_mucous|COVID-19 / group, cell type (main and fine annotations)

CFAP54 CFAP73 EYA1 DNAH7 DNAH11

1.81e-051519558216462e723fec2797387929dde095370947e10a
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP54 CFAP73 SLC9C2 DNAH7 DNAH11

2.05e-051559555f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP54 CFAP73 SLC9C2 DNAH7 DNAH11

2.05e-051559550944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-mature_NK_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AGXT2 PPFIA2 FASTKD1 CUL9 GPR176

2.32e-051599554000ed0d3b7d488722bcd0042fa2ff4405aaab82
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-Natural_Killer_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AGXT2 PPFIA2 FASTKD1 CUL9 GPR176

2.32e-051599557619d0d49738dd08daf01b42664691a5323aa793
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KIAA1549L PIK3C2A SH2D3C TOX2 ATP2A3

2.77e-05165955a74751e0ec857aa974bec04ccc747c004a8f6e01
ToppCellCiliated_cells-B-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

CFAP54 CFAP73 SLC9C2 DNAH7 DNAH11

2.85e-051669554b1056aad8a99827835242b8ab0c7f2bb84471f1
ToppCelllung-Ciliated_Epithelia|lung / shred on tissue and cell subclass

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

2.94e-0516795526cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

4.09e-051799555e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCellCOVID-19-kidney-AQP1+SLC14A1+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

KIAA1549L PIK3C2A DOCK6 TOX2 ATP2A3

4.09e-051799551ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EOGT ATP7A GPRC6A DOCK6 EHD3

4.09e-0517995556db12467b445f2b8ef92af50779eeab10413eb2
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

4.20e-0518095592fb01b91261b3103454924cde56add337b41844
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP54 CFAP73 SLC9C2 DNAH7 DNAH11

4.31e-05181955dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCellCiliated_cells-B-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

4.42e-05182955e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCellControl-Neu_4|World / 5 Neutrophil clusters in COVID-19 patients

GBF1 PIK3C2A ALG9 VPS13A TRMT1L

4.66e-05184955ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP54 DYNC2H1 LRRC49 DNAH7 DNAH11

4.78e-051859555e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellCiliated_cells-B-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

4.78e-05185955f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCellCiliated_cells-B-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

5.03e-051879552b4262c2e7c7830a976be168cee6eeb738d4feda
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP54 CFAP73 SLC9C2 DNAH7 DNAH11

5.03e-051879559e10ed56090d82589bc457788282f664b70ace4b
ToppCell(7)_Epithelial_cells-(7)_Epithelial-F_(Ciliated)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

5.16e-051889555ba5cbb403518026e9040379fb5d99339ea977d8
ToppCellCOPD-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

5.29e-051899553e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCellNasal_Brush-Epithelial-Ciliated_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

5.43e-051909559ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EOGT ATP7A PPFIA2 GPRC6A EHD3

5.43e-051909557e4d80a3a7f83b6a50f1d0fe82fb6c242c39d5b0
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)|343B / Donor, Lineage, Cell class and subclass (all cells)

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

5.43e-05190955169e600e95878000acf5d11f813f9028c7249646
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)-|343B / Donor, Lineage, Cell class and subclass (all cells)

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

5.43e-051909550cc36117c793d83cf4a1f66f47758a07d6712bd3
ToppCellNasal_Brush-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

5.43e-05190955833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCellIPF-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

5.70e-05192955d903bbd6c18e29e2c4cdedeb3fea1fd5ad7baa11
ToppCellCOPD-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

CFAP54 CFAP73 EYA1 DNAH7 DNAH11

5.70e-05192955eab1105cd1a98cfcd3d74dc5c9b89e1799bba59e
ToppCellIPF-Epithelial-Ciliated|IPF / Disease state, Lineage and Cell class

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

5.70e-05192955354adc1354bf596fbc60dd45c0169688e6f45165
ToppCellBronchial_Brush|World / Tissue, Lineage and Cell class of Lung Cells from 10X

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

5.84e-051939553e693ac4c92576e3f2c9efdd3f1d96d3d336e260
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

5.84e-05193955e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCellControl-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

5.84e-051939550e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KIAA1549L SH2D3C TOX2 ATP2A3 GPR176

5.84e-051939552e72309607902dabe3218888b22a77fe941f3570
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

5.84e-05193955ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

5.84e-05193955bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

5.99e-05194955b4ce60c06568123008b1081d644733cb91c28f51
ToppCellControl-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

5.99e-05194955958e648138676d46698090b4046cb484083ae449
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

5.99e-051949557a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

5.99e-051949554a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

5.99e-05194955a46238514bca920c3e3713d23c18ba24a09e2a29
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

6.14e-051959550e763f36786515698b593e5c93f6a56619c1242d
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP73 DYNC2H1 LRRC49 DNAH7 DNAH11

6.14e-051959550fbba312e9ba9b70b4b814b67b6eb1f6544aaf6d
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

6.14e-05195955581b04220587e1d5198b1abd6965965ace7803e7
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

6.14e-0519595593b1559382a12cfb158aa5fac7386e38b4f87989
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

6.14e-051959553486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

6.14e-05195955e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCellBL-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP73 DYNC2H1 LRRC49 DNAH7 DNAH11

6.14e-0519595507a6bcef6af93ed87df455dee624037cb75e011a
ToppCellCOVID-19-Epithelial-Ciliated_cells|Epithelial / Condition, Lineage and Cell class

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

6.29e-05196955de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCellcritical-Epithelial-Ciliated|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

6.29e-0519695527b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

6.29e-05196955d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCellPSB-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP54 DYNC2H1 LRRC49 DNAH7 DNAH11

6.44e-051979556865f4831eb23794fb88a8649d48d497bbae3f44
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

6.44e-0519795571fea4aa6ce96c7693fa94792d08770622873850
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

6.44e-05197955e453d085182364ca347cbcc9dc995c62c3353016
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP54 CFAP73 HABP2 DNAH7 DNAH11

6.44e-051979556e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

6.44e-05197955d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCellControl_saline-Hematopoietic_Erythro-Megakary-Erythro-Mega|Control_saline / Treatment groups by lineage, cell group, cell type

AMFR ITSN1 HECTD4 SESN3 RHAG

6.60e-051989551a39a98beef68e1e6d3adc25270a3336fcc5baf4
ToppCellControl_saline-Hematopoietic_Erythro-Megakary-Erythro-Mega-Erythroid|Control_saline / Treatment groups by lineage, cell group, cell type

AMFR ITSN1 HECTD4 SESN3 RHAG

6.60e-05198955dd80fd9671ee863aebcf4c1023d3e004cc2ee709
ToppCellSigmoid-T_cell-Treg|T_cell / Region, Cell class and subclass

TBC1D4 SESN3 CUL9 TOX2 GPR176

6.60e-05198955e2d2f9f209f77d0c48cfe3e9902c0ae0795511b2
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYT1L KIAA1549L UBE3A PPFIA2 PKD1

6.60e-05198955c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2A SH2D3C DOCK6 TOX2 EHD3

6.60e-051989551378c6d4ceb84b42fdd6556be3296df7a8059e6e
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

6.60e-05198955ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellControl_saline-Hematopoietic_Erythro-Megakary|Control_saline / Treatment groups by lineage, cell group, cell type

AMFR ITSN1 HECTD4 SESN3 RHAG

6.60e-05198955cfc2a860bae883299987d3e374d0476ca20e1bdd
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP54 CFAP73 EYA1 SLC9C2 DNAH7

6.75e-051999552498237b9e895ca4826a3378d9d40989968df72b
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP54 CFAP73 EYA1 SLC9C2 DNAH7

6.75e-05199955542ec45c931b40738df1f3777b00c83be33a514a
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

6.92e-05200955cc906ff02fd335ff633b3b97afceb670494f910a
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

6.92e-0520095579e59ab31d3d3385b1b072dc75508af9546c2e1b
ToppCellBronchus_Control_(B.)-Epithelial-TX-Ciliated|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

6.92e-052009556a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCellControl-Control-Myeloid-immature_Neutrophil|Control / Disease, condition lineage and cell class

GBF1 ALG9 FASTKD1 VPS13A TRMT1L

6.92e-05200955118321ac443feb42aee171baccfc4610f00a8822
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP54 CFAP73 EYA1 SLC9C2 DNAH7

6.92e-05200955926a7ea94b5908aebf103893ea83ce9d25285b65
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CFAP54 CFAP73 GALNT6 SLC9C2 DNAH7

6.92e-05200955da12821e8a0657869ca0f75d351cce2d7605a505
ToppCellBiopsy_IPF-Epithelial-Ciliated|Biopsy_IPF / Sample group, Lineage and Cell type

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

6.92e-05200955bb8c99156e547a8eb6599b6b6bc3c66bf77af7f8
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP54 CFAP73 DYNC2H1 DNAH7 DNAH11

6.92e-05200955873def69bf55ccbfc944bc10c5afc06be019c312
DiseaseAdams-Oliver syndrome

EOGT DOCK6

5.14e-054872cv:C0265268
Diseaseintellectual disability (implicated_via_orthology)

RB1 UBE3A RBL1 ITSN1

7.30e-0575874DOID:1059 (implicated_via_orthology)
DiseaseAdams Oliver syndrome

EOGT DOCK6

1.28e-046872C0265268
DiseaseAdams-Oliver syndrome 1

EOGT DOCK6

1.28e-046872C4551482
DiseaseCongenital defect of skull and scalp

EOGT DOCK6

1.28e-046872C2931779
DiseaseAdams-Oliver syndrome (is_implicated_in)

EOGT DOCK6

1.28e-046872DOID:0060227 (is_implicated_in)
Diseasewaist-hip ratio

DIS3L2 COPB1 DYNC2H1 ALG9 PKD1 HECTD4 CUL9 MGLL DELEC1 ACVR1 EYA1 DOCK6

2.50e-0412268712EFO_0004343
DiseasePolycystic Kidney, Autosomal Dominant

ALG9 PKD1

3.05e-049872C0085413
Diseaseforced expiratory volume, body mass index

DIS3L2 HECTD4

4.65e-0411872EFO_0004314, EFO_0004340
DiseaseConnective Tissue Diseases

PKD1 ACVR1

6.56e-0413872C0009782
Diseaseeosinophil count

TBC1D4 NCKIPSD HECTD4 SESN3 MGLL DELEC1 HABP2 ACVR1 TOX2 ATP2A3 DNAH7 EHD3

1.38e-0314888712EFO_0004842
DiseaseTEMPS-A questionnaire

DYNC2H1 EYA1

2.47e-0325872EFO_0004783
Diseasecorpus collosum mid-posterior volume measurement

KCNV2 LRRC49

2.47e-0325872EFO_0010300
Diseasecerebral amyloid deposition measurement

ITSN1 DELEC1 EFR3A

2.82e-0395873EFO_0007707

Protein segments in the cluster

PeptideGeneStartEntry
LAMLMARAHSNNIDI

AGXT2

176

Q9BYV1
MLMLFVFGVLLHEVS

EOGT

1

Q5NDL2
MMLVSHDFRLIQQVA

ABCF2

566

Q9UG63
MLLKMIFVDNFVHAD

ADCK2

431

Q7Z695
SNSFMMDLHLELIQA

CFAP54

776

Q96N23
MAVLDFLLMQTHSFA

CATSPER1

521

Q8NEC5
GLHVSRMMLAFLVLS

ALG9

166

Q9H6U8
FMLFMHSIAAISLLL

GJA10

211

Q969M2
MLRHENILGFIASDM

ACVR1

256

Q04771
LNAAMHLVLFEDAMQ

DNAH11

2821

Q96DT5
LEHVKLFMQDLSAML

CFAP73

281

A6NFT4
LVEEFMLLANMAVAH

DIS3L2

581

Q8IYB7
IAMEALDQLLMACHS

EFR3A

76

Q14156
AVAMSMALHFLILLV

ATP2A3

936

Q93084
MDFVSFIHLMLRVEN

CAPN14

641

A8MX76
EMINLHSSMFLERQI

ATP7A

691

Q04656
IFHMSLLACALEVVM

RB1

481

P06400
VDVILISNYHCMMAL

INTS9

96

Q9NV88
ARVVHMLVMVALFFT

NPFFR1

266

Q9GZQ6
IHNFTLMESAVLVAM

OR52E2

106

Q8NGJ4
EAELHATLLSMVMVF

GPR176

261

Q14439
LARMLMGLDLLVFAH

MGLL

61

Q99685
DHICVTMDAELIMFL

KIAA1109

4851

Q2LD37
TMDAELIMFLHDLVS

KIAA1109

4856

Q2LD37
FLCELVLFMEHRAQM

BMP15

11

O95972
AMEMSAIAAHNAALL

PCYOX1

466

Q9UHG3
VDTMMLEALAFALAI

OR2W6P

196

Q8NHA6
VLLMMSFDRLVAICH

OR51M1

126

Q9H341
LLQMVFIHVFSVMES

OR51S1

106

Q8NGJ8
IFVLHSFVGSEMMLL

OR4K1

101

Q8NGD4
HFVGAAEMFLLTVMA

OR4Q2

106

P0C623
HFLGASEMFLLTVMA

OR4Q3

106

Q8NH05
NGTLFIMVMHIKDLV

PIK3C2A

1571

O00443
LVIEMVLATDMSCHF

PDE1B

326

Q01064
FVAEAMLLMATILHL

COPB1

581

P53618
RMEEMIFNLADTHLF

EYA1

361

Q99502
DMIMAERLFGILAHV

LRRC49

536

Q8IUZ0
RQQMHMLLEEAFSLA

KIAA1549L

1551

Q6ZVL6
HRFLFLKIMAMLTEL

NR1I2

386

O75469
MAAEVIALLHSLLMA

HECTD4

1661

Q9Y4D8
FLQTLAMIHSIEMIN

GPRC6A

71

Q5T6X5
NELLAGVLLMMHNFE

QTRT2

371

Q9H974
LHIVLIMDSANSNFM

DYNC2H1

2776

Q8NCM8
MFARMSDLHVLLLMA

HABP2

1

Q14520
VLHLADLIRMAFMAA

HEATR5A

1261

Q86XA9
VQDLMFNLHMILTDT

DOCK6

1551

Q96HP0
MLAFTLTAFLELMDH

ELMO2

146

Q96JJ3
GLLAVLHMMVFTDAL

DELEC1

21

Q9P2X7
FCALMIVEEMSVLHE

FITM2

161

Q8N6M3
DHVLDLMLEAMNNLR

GALNT6

51

Q8NCL4
AEEFILAMHLIDVAM

ITSN1

276

Q15811
AEMKVVLALMLLHFR

CYP4F12

476

Q9HCS2
ALELSSFQNIIMRHM

DNAH7

306

Q8WXX0
LLEEMIATLQHFMDD

FASTKD1

516

Q53R41
LFEQAAEQHSRLLMM

CALHM4

231

Q5JW98
RVHLALDVANMVAML

GPR142

391

Q7Z601
LKNMLLVMDTAEIFH

GBF1

1671

Q92538
VFRETGALDLLMHML

CUL9

161

Q8IWT3
RDLAFLVDMTMHLNA

GTF2IRD2

751

Q86UP8
RDLAFLVDMTMHLNA

GTF2IRD2B

751

Q6EKJ0
LAHRFMAEMVDFFIL

FAM8A1

246

Q9UBU6
FMECLVDARMLDHLT

PPFIA2

1041

O75334
VTYMVMAAILHKLDQ

PKD1

3086

P98161
FVLDSAILMAMAFDH

OR52H1

116

Q8NGJ2
IHAFTGMEAEVLLAM

OR52J3

106

Q8NH60
LHSFSIMESAVLLAM

OR52K1

106

Q8NGK4
LHSFSIMESAVLLAM

OR52K2

106

Q8NGK3
RLLAAMNMLHELQFA

MROH5

876

Q6ZUA9
MVFMLLSNLALSHDC

RTTN

2031

Q86VV8
MDANVLMHLRSFDFI

TRMT1L

356

Q7Z2T5
MDMSVLLEQDIFHRS

RBL1

486

P28749
ILEHVEMLCMGFFTL

KCNV2

301

Q8TDN2
TAMLALLTHQFPELM

ST7

526

Q9NRC1
VVDDMLAHDIAQLMV

EHD3

381

Q9NZN3
TMVRELVHNFLMDLC

URB1

301

O60287
MMALIDITVRHIADL

NCKIPSD

636

Q9NZQ3
DFVMELTLLSLDLMH

AMFR

261

Q9UKV5
LHSEVVMALILQYFM

SLC35G4

286

P0C7Q5
LVPMHFNLELSKAMV

VPS13A

741

Q96RL7
HIIDDALVRLEMIAM

UBE3A

531

Q05086
LMYLMDLTHLILDKA

NGDN

61

Q8NEJ9
HVNLLLMEARMQAEL

SESN3

466

P58005
MEAVRLDAEVFMALL

TBC1D10C

216

Q8IV04
VVAYLMIFHNMAILE

STYXL2

236

Q5VZP5
MADEALFLLLHNEMV

TRAPPC6B

1

Q86SZ2
MLIMTILEIVFFAHN

RHAG

141

Q02094
VAAVLLMHMPAEQAF

TBC1D10B

451

Q4KMP7
GVLLLHMSEEQAFEM

TBC1D4

1016

O60343
FINMLLGHMSIEVLR

XPOT

226

O43592
AIMVSNMLAQDSHLL

TOX2

126

Q96NM4
LLSLLMAEMGVHSVA

UCKL1

481

Q9NWZ5
LMEEARLHVAAIQMS

SLC9C2

506

Q5TAH2
LLERFHTMSIMLAVD

SH2D3C

636

Q8N5H7
AGNLMSAMLHVEALE

PTCD1

371

O75127
LGHIDFQELRMMLLS

TCFL5

121

Q9UL49
LLMFLFALAMVLAEN

TCIRG1

411

Q13488
MEAAHMAATAILNLS

MYT1L

726

Q9UL68