Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	nuclear receptor activity	RXRB RXRG THRB NR1I3 NR1H4	2.36e-05	60	114	5	GO:0004879
GeneOntologyMolecularFunction	ligand-activated transcription factor activity	RXRB RXRG THRB NR1I3 NR1H4	2.56e-05	61	114	5	GO:0098531
GeneOntologyMolecularFunction	ATP-dependent activity	MYH10 MYO6 KIF26B KIF21A CCT7 ZNFX1 XRCC5 ABCC6 ATP10D DNAH17 AFG3L2 DNAH6 ATP2B4	4.88e-05	614	114	13	GO:0140657
GeneOntologyMolecularFunction	cytoskeletal motor activity	MYH10 MYO6 KIF26B KIF21A DNAH17 DNAH6	5.95e-05	118	114	6	GO:0003774
GeneOntologyBiologicalProcess	regulation of cholesterol metabolic process	EPHX2 LDLR SCAP THRB NR1H4	1.05e-05	53	113	5	GO:0090181
GeneOntologyBiologicalProcess	regulation of small molecule metabolic process	EPHX2 SIRT7 LDLR FABP5 SCAP THRB AGT LPGAT1 SLC4A4 ATP2B4 NR1H4	2.67e-05	434	113	11	GO:0062012
Domain	ThyrH_rcpt	THRB NR1I3 NR1H4	2.08e-06	5	112	3	IPR001728
Domain	Znf_hrmn_rcpt	RXRB RXRG THRB NR1I3 NR1H4	7.99e-06	46	112	5	IPR001628
Domain	NUCLEAR_REC_DBD_2	RXRB RXRG THRB NR1I3 NR1H4	7.99e-06	46	112	5	PS51030
Domain	NUCLEAR_REC_DBD_1	RXRB RXRG THRB NR1I3 NR1H4	7.99e-06	46	112	5	PS00031
Domain	ZnF_C4	RXRB RXRG THRB NR1I3 NR1H4	7.99e-06	46	112	5	SM00399
Domain	zf-C4	RXRB RXRG THRB NR1I3 NR1H4	7.99e-06	46	112	5	PF00105
Domain	Nuclear_hrmn_rcpt	RXRB RXRG THRB NR1I3 NR1H4	7.99e-06	46	112	5	IPR001723
Domain	-	RXRB RXRG THRB NR1I3 NR1H4	8.89e-06	47	112	5	1.10.565.10
Domain	Nucl_hrmn_rcpt_lig-bd	RXRB RXRG THRB NR1I3 NR1H4	9.88e-06	48	112	5	IPR000536
Domain	HOLI	RXRB RXRG THRB NR1I3 NR1H4	9.88e-06	48	112	5	SM00430
Domain	Hormone_recep	RXRB RXRG THRB NR1I3 NR1H4	9.88e-06	48	112	5	PF00104
Domain	-	RXRB RXRG THRB NR1I3 NR1H4	2.32e-05	57	112	5	3.30.50.10
Domain	Znf_NHR/GATA	RXRB RXRG THRB NR1I3 NR1H4	2.52e-05	58	112	5	IPR013088
Domain	Ribosomal_L10e_CS	RPL10L RPL10	3.56e-05	2	112	2	IPR018255
Domain	Ribosomal_L10e	RPL10L RPL10	3.56e-05	2	112	2	IPR001197
Domain	RIBOSOMAL_L10E	RPL10L RPL10	3.56e-05	2	112	2	PS01257
Domain	ARM-type_fold	ATR ZNFX1 HEATR5A API5 HUWE1 ARFGEF3 XPO5 TELO2 INF2 PI4KA	3.74e-05	339	112	10	IPR016024
Domain	Ribosomal_L10e/L16	RPL10L RPL10	1.07e-04	3	112	2	IPR016180
Domain	-	RPL10L RPL10	1.07e-04	3	112	2	3.90.1170.10
Domain	Ribosomal_L16	RPL10L RPL10	1.07e-04	3	112	2	PF00252
Domain	ARM-like	ATR HEATR5A API5 HUWE1 ARID1B XPO5 TELO2	1.22e-03	270	112	7	IPR011989
Domain	Retinoid-X_rcpt/HNF4	RXRB RXRG	1.55e-03	10	112	2	IPR000003
Domain	-	ATR HEATR5A API5 ARID1B XPO5 TELO2	2.22e-03	222	112	6	1.25.10.10
Domain	calpain_III	CAPN14 CAPN11	2.26e-03	12	112	2	SM00720
Domain	C2_III	CAPN14 CAPN11	2.26e-03	12	112	2	IPR033883
Domain	Calpain_III	CAPN14 CAPN11	2.26e-03	12	112	2	IPR022683
Domain	Calpain_III	CAPN14 CAPN11	2.66e-03	13	112	2	PF01067
Domain	Calpain_domain_III	CAPN14 CAPN11	2.66e-03	13	112	2	IPR022682
Domain	VitD_rcpt	NR1I3 NR1H4	3.09e-03	14	112	2	IPR000324
Domain	Calpain_cysteine_protease	CAPN14 CAPN11	3.09e-03	14	112	2	IPR022684
Domain	Peptidase_C2	CAPN14 CAPN11	3.56e-03	15	112	2	PF00648
Domain	PI3/4_kinase_CS	ATR PI4KA	3.56e-03	15	112	2	IPR018936
Domain	CysPc	CAPN14 CAPN11	3.56e-03	15	112	2	SM00230
Domain	Peptidase_C2_calpain_cat	CAPN14 CAPN11	3.56e-03	15	112	2	IPR001300
Domain	CALPAIN_CAT	CAPN14 CAPN11	3.56e-03	15	112	2	PS50203
Domain	P4Hc	EGLN1 PLOD2	4.05e-03	16	112	2	SM00702
Domain	-	ATR PI4KA	4.05e-03	16	112	2	1.10.1070.11
Domain	PI3Kc	ATR PI4KA	4.05e-03	16	112	2	SM00146
Domain	Pro_4_hyd_alph	EGLN1 PLOD2	4.05e-03	16	112	2	IPR006620
Domain	PI3_PI4_kinase	ATR PI4KA	5.12e-03	18	112	2	PF00454
Domain	PI3_4_KINASE_1	ATR PI4KA	5.12e-03	18	112	2	PS00915
Domain	PI3_4_KINASE_2	ATR PI4KA	5.12e-03	18	112	2	PS00916
Domain	PI3/4_kinase_cat_dom	ATR PI4KA	5.12e-03	18	112	2	IPR000403
Domain	PI3_4_KINASE_3	ATR PI4KA	5.12e-03	18	112	2	PS50290
Domain	2OG-FeII_Oxy	EGLN1 PLOD2	5.70e-03	19	112	2	PF03171
Pathway	REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY	RXRB RXRG THRB NR1I3 NR1H4	1.53e-05	48	93	5	MM14987
Pathway	KEGG_MEDICUS_REFERENCE_THYROID_HORMONE_SIGNALING_PATHWAY	RXRB RXRG THRB	2.27e-05	9	93	3	M47629
Pathway	PID_RXR_VDR_PATHWAY	RXRB RXRG THRB NR1H4	2.37e-05	26	93	4	M162
Pathway	REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY	RXRB RXRG THRB NR1I3 NR1H4	2.51e-05	53	93	5	M8276
Pathway	WP_NUCLEAR_RECEPTORS	RXRB RXRG THRB NR1I3	1.10e-04	38	93	4	M39657
Pathway	WP_NUCLEAR_RECEPTORS	RXRB RXRG THRB NR1I3	1.10e-04	38	93	4	MM15865
Pathway	WP_CHOLESTASIS	LDLR NR1I3 NR1H4	2.49e-04	19	93	3	M45520
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	MYH10 MYO6 WDR7 PPFIA4 CCT7 ZNFX1 LDHA NDUFS2 ARHGAP5 INF2 NEGR1 SV2A AMOT PI4KA AFG3L2 SLC4A4 DNAH6 ATP2B4 RPL10 VCL	6.39e-08	1431	117	20	37142655
Pubmed	Functional proteomics mapping of a human signaling pathway.	MYH10 MYCBP2 MYO6 HUWE1 XAB2 ARHGAP5 ARID1B IL36RN PTPRF XPO5 BRD1 VCL VCPIP1	1.07e-07	591	117	13	15231748
Pubmed	Retinoids activate RXR/CAR-mediated pathway and induce CYP3A.	RXRB RXRG NR1I3	1.48e-07	4	117	3	19686701
Pubmed	Absence of thyroid hormone receptor beta-retinoid X receptor interactions in auditory function and in the pituitary-thyroid axis.	RXRB RXRG THRB	1.48e-07	4	117	3	9804293
Pubmed	Fish oil feeding reverses hepatomegaly and disrupted hepatic function due to the lack of FXR signaling.	LDLR NR1I3 NR1H4	3.69e-07	5	117	3	29142166
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	MYH10 ATR MYO6 ZNFX1 XRCC5 XPO5 LRRC31 PI4KA	4.47e-07	202	117	8	33005030
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	MYO6 HUWE1 NDUFS2 ARFGEF3 SCAP RPRD1A PTPRF XPO5 TELO2 INF2 PI4KA LPGAT1 PLOD2 ATP2B4 VCPIP1	6.70e-07	942	117	15	31073040
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	MYH10 MYCBP2 CCT7 ZNFX1 HUWE1 LDHA NDUFS2 ATL1 ARFGEF3 SV2A GLG1 PI4KA AFG3L2 SLC4A4 RPL10 VCPIP1	1.43e-06	1139	117	16	36417873
Pubmed	Retinoid X receptor (gamma) is necessary to establish the S-opsin gradient in cone photoreceptors of the developing mouse retina.	RXRB RXRG THRB	2.05e-06	8	117	3	16043864
Pubmed	Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.	LDLR RXRB RXRG LIPE SCAP THRB AGT NR1H4	2.21e-06	250	117	8	18660489
Pubmed	A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development.	EPHX2 RXRB RXRG THRB NR1I3 NR1H4	3.09e-06	118	117	6	16971476
Pubmed	USP11 mediates repair of DNA-protein cross-links by deubiquitinating SPRTN metalloprotease.	RPL10L MYH10 MYO6 CCT7 XRCC5 NDUFS2 TELO2 DCUN1D2 AFG3L2 PLOD2 RPL10	3.47e-06	565	117	11	33567341
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	MYH10 LAMTOR2 MYCBP2 KIF21A GXYLT1 CCT7 XRCC5 LDHA LDLR XAB2 XPO5 GLG1 AFG3L2 PLOD2 PCID2 RPL10	7.44e-06	1297	117	16	33545068
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	KIF26B KIF21A OBSCN HUWE1 XRCC5 NDUFS2 ARHGAP5 AMOT PI4KA UGCG KDM8 RPL10	7.46e-06	736	117	12	29676528
Pubmed	Cholesterol and cholesterol plus DHA diet-induced gene expression and fatty acid changes in mouse eye and brain.	RXRB RXRG FABP5	7.98e-06	12	117	3	15589691
Pubmed	Defining the membrane proteome of NK cells.	RPL10L MYCBP2 MYO6 API5 HUWE1 PSTPIP1 XRCC5 LDHA LDLR XAB2 GLG1 PI4KA LPGAT1 ATP2B4 RPL10	9.17e-06	1168	117	15	19946888
Pubmed	Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.	RPL10L MYH10 OBSCN FABP5 PI4KA AFG3L2 RPL10 VCL	9.29e-06	304	117	8	32235678
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	MYH10 WDR7 HEATR5A ADCY2 ARFGEF3 XPO5 NEGR1 SV2A VCPIP1	1.02e-05	407	117	9	12693553
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	MYH10 MYCBP2 MYO6 EGLN1 MRPL28 CCT7 HUWE1 XRCC5 NDUFS2 TBC1D17 ATL1 ARFGEF3 TELO2 INF2 PI4KA AFG3L2 VCPIP1	1.10e-05	1496	117	17	32877691
Pubmed	ABCC6 deficiency promotes dyslipidemia and atherosclerosis.	LDLR ABCC6	1.12e-05	2	117	2	33594095
Pubmed	The LDL receptor is not necessary for acute adrenal steroidogenesis in mouse adrenocortical cells.	LDLR LIPE	1.12e-05	2	117	2	16985254
Pubmed	Human species-specific loss of CMP-N-acetylneuraminic acid hydroxylase enhances atherosclerosis via intrinsic and extrinsic mechanisms.	LDLR CMAHP	1.12e-05	2	117	2	31332008
Pubmed	Homozygosity for angiotensinogen 235T variant increases the risk of myocardial infarction in patients with multi-vessel coronary artery disease.	ATR AGT	1.12e-05	2	117	2	11393670
Pubmed	Suppression of retinoic acid receptor beta in non-small-cell lung cancer in vivo: implications for lung cancer development.	RXRB RXRG	1.12e-05	2	117	2	9150186
Pubmed	Nr1h4 and Thrb ameliorate ER stress and provide protection in the MPTP mouse model of Parkinson's.	THRB NR1H4	1.12e-05	2	117	2	38609183
Pubmed	Dietary Neu5Ac Intervention Protects Against Atherosclerosis Associated With Human-Like Neu5Gc Loss-Brief Report.	LDLR CMAHP	1.12e-05	2	117	2	34587757
Pubmed	Farnesoid X Receptor Activation by Obeticholic Acid Elevates Liver Low-Density Lipoprotein Receptor Expression by mRNA Stabilization and Reduces Plasma Low-Density Lipoprotein Cholesterol in Mice.	LDLR NR1H4	1.12e-05	2	117	2	30354208
Pubmed	Angiotensin II increases activity of the ClC-K2 Cl- channel in collecting duct intercalated cells by stimulating production of reactive oxygen species.	CLCNKB AGT	1.12e-05	2	117	2	33524393
Pubmed	FXR deficiency causes reduced atherosclerosis in Ldlr-/- mice.	LDLR NR1H4	1.12e-05	2	117	2	16825595
Pubmed	Cys18-Cys137 disulfide bond in mouse angiotensinogen does not affect AngII-dependent functions in vivo.	LDLR AGT	1.12e-05	2	117	2	25691624
Pubmed	Microarray analysis indicates an important role for FABP5 and putative novel FABPs on a Western-type diet.	LDLR FABP5	1.12e-05	2	117	2	16885566
Pubmed	Inhibition of SREBP by a small molecule, betulin, improves hyperlipidemia and insulin resistance and reduces atherosclerotic plaques.	LDLR SCAP	1.12e-05	2	117	2	21195348
Pubmed	Angiotensinogen Exerts Effects Independent of Angiotensin II.	LDLR AGT	1.12e-05	2	117	2	26681751
Pubmed	Search for genetic variants in the retinoid X receptor-gamma-gene by polymerase chain reaction-single-strand conformation polymorphism in patients with resistance to thyroid hormone without mutations in thyroid hormone receptor beta gene.	RXRG THRB	1.12e-05	2	117	2	15186611
Pubmed	Alteration in Rab11-mediated endocytic trafficking of LDL receptor contributes to angiotensin II-induced cholesterol accumulation and injury in podocytes.	LDLR AGT	1.12e-05	2	117	2	35567428
Pubmed	The thyrotropin beta-subunit gene is repressed by thyroid hormone in a novel thyrotrope cell line, mouse T alphaT1 cells.	RXRG THRB	1.12e-05	2	117	2	9794455
Pubmed	Hypoxia-Inducible Factor Prolyl 4-Hydroxylase-2 Inhibition Protects Against Development of Atherosclerosis.	EGLN1 LDLR	1.12e-05	2	117	2	26848160
Pubmed	An unexpected intriguing effect of Toll-like receptor regulator RP105 (CD180) on atherosclerosis formation with alterations on B-cell activation.	LDLR CD180	1.12e-05	2	117	2	24115036
Pubmed	Retinoid x receptor gamma control of affective behaviors involves dopaminergic signaling in mice.	RXRB RXRG	1.12e-05	2	117	2	20620876
Pubmed	Exhaustion-associated cholesterol deficiency dampens the cytotoxic arm of antitumor immunity.	LDLR SCAP	1.12e-05	2	117	2	37244259
Pubmed	Bile acid homeostasis controls CAR signaling pathways in mouse testis through FXRalpha.	NR1I3 NR1H4	1.12e-05	2	117	2	28181583
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	XRCC5 LDLR ATL1 FABP5 ARID1B PTPRF XPO5 SV2A GLG1 AMOT SLC5A6 AFG3L2 LPGAT1 PCID2 RPL10	1.30e-05	1203	117	15	29180619
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	RPL10L MYH10 CCT7 API5 XRCC5 LDHA RPRD1A PI4KA RPL10 VCL	1.47e-05	538	117	10	28524877
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	MYH10 MYCBP2 CCT7 HUWE1 XRCC5 LDHA ARID1B GLG1 LPGAT1 SPAG17 RPL10 VCL	1.86e-05	807	117	12	30575818
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	MYO6 MRPL28 NDUFS2 XAB2 INTS10 XPO5 TELO2 GLG1 AFG3L2 PCID2	2.07e-05	560	117	10	35241646
Pubmed	SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response.	MYH10 CCT7 HUWE1 XRCC5 LDHA NDUFS2 RPRD1A AFG3L2 RPL10	2.82e-05	463	117	9	34901782
Pubmed	Retinoic acid receptor-related orphan receptor alpha regulates a subset of cone genes during mouse retinal development.	RXRG THRB CNGB3	2.92e-05	18	117	3	19014374
Pubmed	Blood-Brain Barrier: From Physiology to Disease and Back.	SLC15A2 SLC5A6 SLC4A4 ATP2B4 VCL	2.92e-05	105	117	5	30280653
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	MYH10 MYCBP2 MYO6 CCT7 API5 HUWE1 XRCC5 LDHA FABP5 XPO5 AMOT PLOD2 RPL10 VCL	3.32e-05	1149	117	14	35446349
Pubmed	Rapsyn is required for MuSK signaling and recruits synaptic components to a MuSK-containing scaffold.	RAPSN SV2A	3.36e-05	3	117	2	9136771
Pubmed	Transgenic expression of CYP7A1 in LDL receptor-deficient mice blocks diet-induced hypercholesterolemia.	LDLR NR1H4	3.36e-05	3	117	2	16609145
Pubmed	Constitutive androstane receptor activation decreases plasma apolipoprotein B-containing lipoproteins and atherosclerosis in low-density lipoprotein receptor-deficient mice.	LDLR NR1I3	3.36e-05	3	117	2	21778422
Pubmed	Crystal structure of the ligand-binding domain of the ultraspiracle protein USP, the ortholog of retinoid X receptors in insects.	RXRB RXRG	3.36e-05	3	117	2	11053444
Pubmed	Farnesoid X receptor suppresses constitutive androstane receptor activity at the multidrug resistance protein-4 promoter.	NR1I3 NR1H4	3.36e-05	3	117	2	21296199
Pubmed	Impaired locomotion and dopamine signaling in retinoid receptor mutant mice.	RXRB RXRG	3.36e-05	3	117	2	9452386
Pubmed	Deficiency of the TLR4 analogue RP105 aggravates vein graft disease by inducing a pro-inflammatory response.	LDLR CD180	3.36e-05	3	117	2	27053419
Pubmed	Retinoid X receptors: X-ploring their (patho)physiological functions.	RXRB RXRG	3.36e-05	3	117	2	15608692
Pubmed	HCLK2 is essential for the mammalian S-phase checkpoint and impacts on Chk1 stability.	ATR TELO2	3.36e-05	3	117	2	17384638
Pubmed	Retinoid receptors trigger neuritogenesis in retinal degenerations.	RXRB RXRG	3.36e-05	3	117	2	21940995
Pubmed	The Deubiquitylase USP2 Regulates the LDLR Pathway by Counteracting the E3-Ubiquitin Ligase IDOL.	LDLR USP2	3.36e-05	3	117	2	26666640
Pubmed	Angiotensin II increases vascular proteoglycan content preceding and contributing to atherosclerosis development.	LDLR AGT	3.36e-05	3	117	2	18033753
Pubmed	An essential role for retinoid receptors RARbeta and RXRgamma in long-term potentiation and depression.	RXRB RXRG	3.36e-05	3	117	2	9883728
Pubmed	RXR gamma null mice are apparently normal and compound RXR alpha +/-/RXR beta -/-/RXR gamma -/- mutant mice are viable.	RXRB RXRG	3.36e-05	3	117	2	8799145
Pubmed	Macrophage Mal1 deficiency suppresses atherosclerosis in low-density lipoprotein receptor-null mice by activating peroxisome proliferator-activated receptor-γ-regulated genes.	LDLR FABP5	3.36e-05	3	117	2	21474828
Pubmed	Cooperative formation of high-order oligomers by retinoid X receptors: an unexpected mode of DNA recognition.	RXRB RXRG	3.36e-05	3	117	2	7831303
Pubmed	Simultaneous inhibition of FXR and TGR5 exacerbates atherosclerotic formation.	LDLR NR1H4	3.36e-05	3	117	2	29976576
Pubmed	Characterization of the GNMT-HectH9-PREX2 tripartite relationship in the pathogenesis of hepatocellular carcinoma.	HUWE1 PREX2	3.36e-05	3	117	2	28205209
Pubmed	Characterization of three RXR genes that mediate the action of 9-cis retinoic acid.	RXRB RXRG	3.36e-05	3	117	2	1312497
Pubmed	Detection of retinoid X receptors using specific monoclonal and polyclonal antibodies.	RXRB RXRG	3.36e-05	3	117	2	7980510
Pubmed	Immunohistochemical detection of the retinoid X receptors alpha, beta, and gamma in human prostate.	RXRB RXRG	3.36e-05	3	117	2	12514092
Pubmed	Fatty acid-binding protein-hormone-sensitive lipase interaction. Fatty acid dependence on binding.	FABP5 LIPE	3.36e-05	3	117	2	13129924
Pubmed	Analysis of exome-sequenced UK Biobank subjects implicates genes affecting risk of hyperlipidaemia.	HUWE1 LDLR	3.36e-05	3	117	2	32747172
Pubmed	Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity.	NR1I3 NR1H4	3.36e-05	3	117	2	12923173
Pubmed	Loss of FXR protects against diet-induced obesity and accelerates liver carcinogenesis in ob/ob mice.	LDLR NR1H4	3.36e-05	3	117	2	22261820
Pubmed	Chromosomal localization of the human retinoid X receptors.	RXRB RXRG	3.36e-05	3	117	2	8034312
Pubmed	Loss of small heterodimer partner expression in the liver protects against dyslipidemia.	LDLR NR1H4	3.36e-05	3	117	2	18820241
Pubmed	Identification of the promoter elements involved in the stimulation of ASCT2 expression by glutamine availability in HepG2 cells and the probable involvement of FXR/RXR dimers.	RXRG NR1H4	3.36e-05	3	117	2	16197915
Pubmed	Somatic mutations of PREX2 gene in patients with hepatocellular carcinoma.	HUWE1 PREX2	3.36e-05	3	117	2	30796242
Pubmed	The role of retinoid X receptor messenger RNA expression in curatively resected non-small cell lung cancer.	RXRB RXRG	3.36e-05	3	117	2	11839661
Pubmed	Angiotensinogen and Megalin Interactions Contribute to Atherosclerosis-Brief Report.	LDLR AGT	3.36e-05	3	117	2	30567480
Pubmed	Adipocyte-derived lactate is a signalling metabolite that potentiates adipose macrophage inflammation via targeting PHD2.	EGLN1 LDHA	3.36e-05	3	117	2	36064857
Pubmed	PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.	MYH10 ATR MYO6 CCT7 HUWE1 LDHA FABP5 RPL10 VCL	3.55e-05	477	117	9	31300519
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	FAM184B MYCBP2 MYO6 MRPL28 XRCC5 NDUFS2 TBC1D17 TELO2 INF2 PTCD1 GLG1 PI4KA AFG3L2 PLOD2 ATP2B4 VCL	3.95e-05	1487	117	16	33957083
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	TBL1Y CCT7 API5 SIRT7 NDUFS2 XAB2 INTS10 PTCD1 GLG1 PI4KA SLC5A6 AFG3L2 INTS15 NR1I3 PCID2 RPL10	4.27e-05	1497	117	16	31527615
Pubmed	Common genetic variation in multiple metabolic pathways influences susceptibility to low HDL-cholesterol and coronary heart disease.	ABCC6 RXRG LIPE NR1H4	4.80e-05	59	117	4	20855565
Pubmed	ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.	MYH10 MYCBP2 MYO6 CCT7 HUWE1 XRCC5 LDHA FABP5 PCID2 RPL10	5.14e-05	624	117	10	33729478
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	ATR API5 HUWE1 XRCC5 NDUFS2 FABP5 ARID1B RPRD1A	6.10e-05	396	117	8	26687479
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	MYO6 WDR7 EGLN1 CCT7 HUWE1 LDHA ARFGEF3 LIPE AMOT PI4KA RPL10	6.54e-05	777	117	11	35844135
Pubmed	Retinoic acid biosynthetic activity and retinoid receptors in the olfactory mucosa of adult mice.	RXRB RXRG	6.70e-05	4	117	2	10079186
Pubmed	Genome-wide association study using diversity outcross mice identified candidate genes of pancreatic cancer.	ARID1B KCNJ6	6.70e-05	4	117	2	30578891
Pubmed	Hormone-sensitive lipase deficiency affects the expression of SR-BI, LDLr, and ABCA1 receptors/transporters involved in cellular cholesterol uptake and efflux and disturbs fertility in mouse testis.	LDLR LIPE	6.70e-05	4	117	2	34461308
Pubmed	Loss of retinoid X receptor gamma subunit impairs group 1 mGluR mediated electrophysiological responses and group 1 mGluR dependent behaviors.	RXRB RXRG	6.70e-05	4	117	2	33692389
Pubmed	Retinoic X receptor subtypes exert differential effects on the regulation of Trh transcription.	RXRB THRB	6.70e-05	4	117	2	23896434
Pubmed	Knocking Out Non-muscle Myosin II in Retinal Ganglion Cells Promotes Long-Distance Optic Nerve Regeneration.	MYH10 AVIL	6.70e-05	4	117	2	32320663
Pubmed	HCLK2 is required for activity of the DNA damage response kinase ATR.	ATR TELO2	6.70e-05	4	117	2	19097996
Pubmed	The nuclear receptor FXR uncouples the actions of miR-33 from SREBP-2.	SCAP NR1H4	6.70e-05	4	117	2	25593129
Pubmed	Lack of association of the renin-angiotensin system genes polymorphisms and left ventricular hypertrophy in hypertension.	ATR AGT	6.70e-05	4	117	2	11688760
Pubmed	Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently.	RXRB RXRG	6.70e-05	4	117	2	1310259
Pubmed	Ablation of neutral cholesterol ester hydrolase 1 accelerates atherosclerosis.	LDLR LIPE	6.70e-05	4	117	2	19723498
Pubmed	Pregnane X Receptor Expression in Human Pancreatic Adenocarcinoma: Associations With Clinicopathologic Parameters, Tumor Proliferative Capacity, Patients' Survival, and Retinoid X Receptor Expression.	RXRB RXRG	6.70e-05	4	117	2	26355550
GeneFamily	Nuclear hormone receptors	RXRB RXRG THRB NR1I3 NR1H4	2.30e-06	49	79	5	71
ToppCell	LA-11._Adipocyte\|LA / Chamber and Cluster_Paper	MYCBP2 TBL1Y DUSP4 ABCC6 SCRN2 LIPE PTPRF SLC4A4	3.00e-08	183	117	8	3f9011976782fa8aa95cdd6f00f07a91094d411b
ToppCell	LPS-antiTNF-Endothelial-Epi-like\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC25A18 PPFIA4 USP2 CLCNKB SLC15A2 SLC5A6 DNAH6	1.10e-07	144	117	7	75b16adfbe84f69376e6566d531ba7919d5c5192
ToppCell	facs-Kidney-nan-24m-Epithelial-kidney_collecting_duct_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF21A ADAMTS13 SCRN2 CALML4 XYLB SLC4A4 NR1H4	4.46e-07	177	117	7	9c7c6824b9011363851f084a500d665f025b026e
ToppCell	facs-Kidney-nan-24m-Epithelial-kidney_collecting_duct_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF21A ADAMTS13 SCRN2 CALML4 XYLB SLC4A4 NR1H4	4.46e-07	177	117	7	2bf639e9e801e5144462ffc957f5739e0dfcd500
ToppCell	LA-11._Adipocyte\|World / Chamber and Cluster_Paper	TBL1Y DUSP4 ABCC6 SCRN2 LIPE PTPRF SLC4A4	5.58e-07	183	117	7	b177be283e1553fb1f69a346f1ba79ad00297fa2
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_only / Treatment groups by lineage, cell group, cell type	KIF21A LDLR ARFGEF3 LIPE PTPRF IKBKE SLC4A4	9.16e-07	197	117	7	1a1bee8da6e04b65935c40373eaee4d6c046d9a1
ToppCell	356C-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SYCP2L ZNFX1 LDLR ARHGAP5 TELO2 KDM8	5.69e-06	169	117	6	0425d2580ed325178f522c0093ff4623de6ce7a8
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_11\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DUSP4 PREX2 SLCO5A1 THRB NEGR1 QPCT	5.69e-06	169	117	6	e3410ccb3f85811c75694e286115803911169a2f
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_11\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DUSP4 PREX2 SLCO5A1 THRB NEGR1 QPCT	5.69e-06	169	117	6	a4f610d07c3ba5537f4497f523669b914f7eddc1
ToppCell	356C-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SYCP2L ZNFX1 LDLR ARHGAP5 TELO2 KDM8	5.69e-06	169	117	6	fec669968a77060bd77ee8695034e35a642c984f
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADCY2 PTPRF SLC15A2 AMOT SLC4A4 VCL	6.73e-06	174	117	6	42f2ba54b4ea4c62482582b0ccdadffae0a5eb4a
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIA4 ADCY2 AVIL AGT CD180 ANKRD33B	6.95e-06	175	117	6	f24b664b9056b5976bf2222e8013f15c09e049ad
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LDLR ABCC6 PTPRF AGT XYLB SLC4A4	8.70e-06	182	117	6	770ce9f3f4538d0181a0181543841bc964c68274
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHX2 SCRN2 CALML4 XYLB SLC4A4 NR1H4	8.70e-06	182	117	6	faf0dfa3adc2d2706b6942b5127093ccdc856447
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHX2 SCRN2 CALML4 XYLB SLC4A4 NR1H4	8.70e-06	182	117	6	be8dd52898525ce6632af0adc2801944f3ac10bd
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LDLR ABCC6 PTPRF AGT XYLB SLC4A4	8.70e-06	182	117	6	77ab860e2add49dad0c1ffbfc64278ad499dfbd5
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LDLR ABCC6 PTPRF AGT XYLB SLC4A4	8.70e-06	182	117	6	4921c7d5687cc79f896b39753bb621d7e3d2972f
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF26B OBSCN ARFGEF3 MYOM2 SLC4A4 SPAG17	9.26e-06	184	117	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF26B OBSCN ARFGEF3 MYOM2 SLC4A4 SPAG17	9.26e-06	184	117	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF26B OBSCN ARFGEF3 MYOM2 SLC4A4 SPAG17	9.26e-06	184	117	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KIF21A ADCY2 ABCC6 UGCG XYLB ANKRD33B	9.84e-06	186	117	6	f28d72b47624b69a580b4429e2be560a26898591
ToppCell	10x5'-Liver-Myeloid_Dendritic-DC1\|Liver / Manually curated celltypes from each tissue	SYCP2L PREX2 SLCO5A1 ARHGAP5 INF2 NEGR1	9.84e-06	186	117	6	e823529ffd06352c6bdec102f221fdf27f7c7369
ToppCell	RA-11._Adipocyte\|World / Chamber and Cluster_Paper	MYCBP2 DUSP4 LDLR SCRN2 LIPE PTPRF	1.05e-05	188	117	6	4dac9d636e5cad4cda540b93d4bfed6b5732c880
ToppCell	pdx-Tumor_cells-T8\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	ABCC6 THRB KDM8 XYLB NR1I3 NR1H4	1.11e-05	190	117	6	b05db0de9b6ae01dd30074453f7de44f7397631e
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	MYCBP2 WDR7 HUWE1 LDLR GLG1 XYLB	1.14e-05	191	117	6	9454f642c3621370fa23640b631301346b300950
ToppCell	droplet-Bladder-Unstain-18m-Epithelial-basal_bladder_epithelial_cell_(Krt5+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LDLR CAPN11 PTPRF PROM2 UGCG RPL10	1.14e-05	191	117	6	49068e3b7d265d4767d7b3c79d455dbc2fd8c6cd
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHX2 SLC25A18 PREX2 SLC15A2 AGT SLC4A4	1.18e-05	192	117	6	d2161842a38146261847fc9061ba9322e0f087e0
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHX2 SLC25A18 PREX2 SLC15A2 AGT SLC4A4	1.18e-05	192	117	6	261211a86e6f63b09c2ddce1d2d9257d311f1770
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	KIF21A OBSCN SLCO5A1 MYOM2 ATP2B4 VCL	1.21e-05	193	117	6	dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell	droplet-Kidney-nan-21m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAPSN ARFGEF3 PTPRF CLCNKB PROM2 ATP2B4	1.21e-05	193	117	6	b397c14ac1e34c6be3f25d4417d200bc518d3048
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCBP2 MYO6 KIF21A HUWE1 LDLR PTPRF	1.29e-05	195	117	6	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCBP2 MYO6 KIF21A HUWE1 LDLR PTPRF	1.29e-05	195	117	6	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-ventral_progenitors_and_neurons_1\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	MYCBP2 ST8SIA3 RXRG NEGR1 SV2A KCNJ6	1.36e-05	197	117	6	4961f66606f08e399508fd6cabca588e7ab406a8
ToppCell	facs-Tongue-nan-3m-Epithelial\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO6 API5 HUWE1 ARHGAP5 GLG1 VCL	1.40e-05	198	117	6	2f03f8897dd7cce6d8296638e14e11ec16bcf624
ToppCell	facs-Tongue-nan-3m\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO6 API5 HUWE1 ARHGAP5 GLG1 VCL	1.40e-05	198	117	6	f2a4057f038ef7225a5b98a7ab068c30dff4eadd
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Macroglial\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	SLC25A18 PREX2 SLC15A2 SLC4A4 PLOD2 ATP2B4	1.49e-05	200	117	6	3a954d9d542e52c9b181f0850a09b1bff0a0c82d
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-Macroglial-Astrocyte\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	SLC25A18 FABP5 SLC15A2 AGT SLC4A4 ATP2B4	1.49e-05	200	117	6	158ba898312c73bcb54c675a4860874a1dd58662
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SLC25A18 ADCY2 PREX2 SLC15A2 AGT SLC4A4	1.49e-05	200	117	6	07d942803360e1a1e8e131d6e31c726dd0db1a0b
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SLC25A18 MYO6 ADCY2 PREX2 SLC15A2 AGT	1.49e-05	200	117	6	d0812817ef99608994193787a62d39adeb2070ca
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Macroglial-Astrocyte\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	SLC25A18 PREX2 SLC15A2 AGT SLC4A4 PLOD2	1.49e-05	200	117	6	7c66953ff6d8f16f4decd23c85232990d2d8c6c4
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SLC25A18 MYO6 ADCY2 PREX2 SLC15A2 AGT	1.49e-05	200	117	6	cd54ddf1919c98e84b7e4aba85b374fc8b407206
ToppCell	356C-Fibroblasts-Fibroblast-H-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SLC25A18 SIRT7 SLC15A2 SV2A KDM8	4.93e-05	151	117	5	2dc132895609e4efe17954e31f53d9c1ccf256ef
ToppCell	Cerebellum-Macroglia-ASTROCYTE\|Cerebellum / BrainAtlas - Mouse McCarroll V32	SLC25A18 RXRG SLC15A2 AGT SLC4A4	4.93e-05	151	117	5	71841d2001200d1595c85c2b007ee20791a72927
ToppCell	356C-Fibroblasts-Fibroblast-H\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SLC25A18 SIRT7 SLC15A2 SV2A KDM8	4.93e-05	151	117	5	22afd8201eff8471da3456be065f2790de5e4bfe
ToppCell	Cerebellum-Macroglia-ASTROCYTE-Gja1\|Cerebellum / BrainAtlas - Mouse McCarroll V32	SLC25A18 RXRG SLC15A2 AGT SLC4A4	4.93e-05	151	117	5	60aced0c1cc6b509b73308d03d58a3c44d712ef4
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHX2 FAM184B IKBKE CNGB3 TMPRSS7	5.42e-05	154	117	5	5ed64bbf603290e6dc34f81d145982690b89dd0d
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L6_CT\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CABP5 OBSCN IL36RN INF2 ATP2B4	5.76e-05	156	117	5	fe383ce3a0c37f7343d7026cb51260a04d4c2829
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L6_IT\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ADAMTS13 INF2 ANKRD33B ATP2B4 RPL10	6.12e-05	158	117	5	9e0589f770920f8ac41cfe5cd0a29e9e7a04a308
ToppCell	metastatic_Brain-T/NK_cells-Cytotoxic_CD8+_T\|T/NK_cells / Location, Cell class and cell subclass	ARHGAP5 SLC15A2 AMOT TSSK3 CD180	6.69e-05	161	117	5	e6e294b4ba911c1327664f1a0f93207096c6de03
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D17 ARFGEF3 SLC15A2 AGT SLC4A4	6.69e-05	161	117	5	9f02b94e29e60d50e92eaa748ebf0c36d3671bb3
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC25A18 ARFGEF3 USP2 THRB DNAH6	7.09e-05	163	117	5	cab65dabeea58141c649e4fec5e0123beb3de1b3
ToppCell	metastatic_Lymph_Node-Myeloid_cells-CD141+_DCs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	DUSP4 PREX2 SLCO5A1 NEGR1 QPCT	7.73e-05	166	117	5	9f14e3ef19d5903278c040be1c477501237173fa
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Stem_cells-neuroepithelial-like_cells\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	SYCP2L OBSCN DCUN1D2 MYOM2 BRD1	7.95e-05	167	117	5	e488d9c7cf4355959e3833de3bd496c13fc11b1b
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IL36RN SLC15A2 PROM2 AMOT TSSK3	8.41e-05	169	117	5	40b557549fe08c5dc9dba359af35993d68d1640a
ToppCell	droplet-Kidney-nan-3m-Epithelial-brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC15A2 AGT LPGAT1 TMPRSS7 NR1I3	8.65e-05	170	117	5	dd48fd3c5c67eb71183981f42975a538f12077c3
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial-N_cells_(NTS+)\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ST8SIA3 ADCY2 ARFGEF3 KCNJ6 QPCT	8.65e-05	170	117	5	02f0be0aab8ba2d35a83238609352ef3677511c9
ToppCell	droplet-Spleen-nan-18m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIA4 OBSCN ARHGAP5 PTPRF PLOD2	8.89e-05	171	117	5	4e856441063e9825b6f87a1d3dd19c77dae4662c
ToppCell	COVID-19_Mild-Neu_2\|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients	ARFGEF3 ARHGAP5 UGCG CALML4 TSSK3	9.13e-05	172	117	5	f5fd08b42c002d4693646b27e7b708eceb49524f
ToppCell	10x5'-Lung-Myeloid_Dendritic-DC1\|Lung / Manually curated celltypes from each tissue	DUSP4 PREX2 ARHGAP5 THRB NEGR1	9.13e-05	172	117	5	243b8bb01cbec5c1bf8802cbf8a6153356b4c384
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADCY2 FER1L6-AS1 SLC15A2 PROM2 SLC4A4	9.39e-05	173	117	5	464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCell	metastatic_Brain-Myeloid_cells-Activated_DCs\|Myeloid_cells / Location, Cell class and cell subclass	DUSP4 SLCO5A1 AMOT SLC4A4 ANKRD33B	1.02e-04	176	117	5	9c1f255de3082b3da4bef2a9bdff710cfd48261f
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ST8SIA3 ADCY2 ARFGEF3 KCNJ6 SPAG17	1.02e-04	176	117	5	2e1003dc373b14d27f0464d980453fdcfc1005f0
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC25A18 PREX2 SLC15A2 AGT SLC4A4	1.02e-04	176	117	5	ac3dc44755280e36c0947b6de3cd639dc17de8b6
ToppCell	367C-Myeloid-Dendritic-cDC_activated\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	DUSP4 SLCO5A1 PTPRF UGCG ANKRD33B	1.05e-04	177	117	5	a0ff337f11bdb11959ac71805ff94be6b4ec1083
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC25A18 OBSCN PREX2 PTCD1 KCNJ6	1.10e-04	179	117	5	dc6cd46fa652b296ddbc41855f6377946d0a4cdc
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KIF21A ABCC6 UGCG XYLB ANKRD33B	1.10e-04	179	117	5	58ae5a97fe2a14e1c6fdeb886397eb06fdaf0428
ToppCell	facs-Marrow-B-cells-3m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIA4 OBSCN ARHGAP5 PTPRF CMAHP	1.13e-04	180	117	5	bf8d13d4db1af55b8c9fe16aaccf8743e000e005
ToppCell	facs-Marrow-B-cells-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIA4 OBSCN ARHGAP5 PTPRF CMAHP	1.13e-04	180	117	5	839defb40f7cfb2711e9025194de636533f51bcd
ToppCell	10x5'-Lung-Myeloid_Dendritic-migDC\|Lung / Manually curated celltypes from each tissue	DUSP4 SLCO5A1 PTPRF UGCG ANKRD33B	1.13e-04	180	117	5	e9e8992deb0beeee5548910e4616e7c990763d99
ToppCell	RA-11._Adipocyte\|RA / Chamber and Cluster_Paper	DUSP4 SCRN2 LIPE PTPRF SLC4A4	1.13e-04	180	117	5	d48a3d27357f7d184132a6805950f93080146b59
ToppCell	facs-Marrow-B-cells-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIA4 OBSCN ARHGAP5 PTPRF CMAHP	1.13e-04	180	117	5	82965ed1b72a1873c24dd4553d39681596057316
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_B-Branch_B2_(eMN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KIF21A DUSP4 ST8SIA3 ATL1 KCNJ6	1.13e-04	180	117	5	368ff7fcfd21ad248f96a83a8b191040ba7d8670
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-M/X_cells_(MLN/GHRL+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ST8SIA3 ARFGEF3 KCNJ6 AGT QPCT	1.16e-04	181	117	5	af031661af28f99d906d8e013b4949133b44a2e6
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADCY2 ARFGEF3 SLC15A2 PROM2 SLC4A4	1.19e-04	182	117	5	3f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCell	facs-Liver-Hepatocytes-24m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LDLR ABCC6 PTPRF AGT SLC4A4	1.22e-04	183	117	5	d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCell	Epithelial-lung_goblet_cell\|World / Lineage, Cell type, age group and donor	ADCY2 ARFGEF3 SLC15A2 PROM2 SLC4A4	1.22e-04	183	117	5	940cbe298e9c53b5622af09264586ed823d3141f
ToppCell	Control-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	DUSP4 SLCO5A1 ARHGAP5 THRB NEGR1	1.25e-04	184	117	5	c6affa0b12510363258f65e46bf2d47bf4a8e75f
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYH10 ADAMTS13 ATL1 NEGR1 SLC4A4	1.29e-04	185	117	5	6712512100ccef456d2e2bd201d0987986c92ac9
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHX2 NDUFS2 SCRN2 USP2 SLC4A4	1.32e-04	186	117	5	fa5f602f01de5beec529d9f5208172b2914a952d
ToppCell	droplet-Heart-nan-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO6 PREX2 FABP5 ARHGAP5 ATP2B4	1.32e-04	186	117	5	0ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell	Control-Myeloid-cDC1\|World / Disease state, Lineage and Cell class	DUSP4 SLCO5A1 ARHGAP5 THRB NEGR1	1.32e-04	186	117	5	3de803dee3ef10eb85a2b47d3f93385214e5b0ff
ToppCell	droplet-Limb_Muscle-nan-24m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM184B RXRG ATL1 NEGR1 PROM2	1.32e-04	186	117	5	ea936e66ae4b7b40564711fad60ac0137327995f
ToppCell	Control-Myeloid-cDC1\|Control / Disease state, Lineage and Cell class	DUSP4 SLCO5A1 ARHGAP5 THRB NEGR1	1.32e-04	186	117	5	b05c394aa3573ba855abc3066739ca193883b0c3
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-25\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	QPCT MYOM2 CMAHP NR1H4 RPL10	1.35e-04	187	117	5	0d4b7da81036c2aa678654b9fe49c939d08fcd9b
ToppCell	3'-Adult-LargeIntestine-Hematopoietic-Myeloid-Lymphoid_DC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KIF26B DUSP4 SLCO5A1 CD180 ANKRD33B	1.35e-04	187	117	5	d69f4eee0304a7db226275ab77fc9d5d2b6f3a07
ToppCell	COVID-19-kidney-tDL\|kidney / Disease (COVID-19 only), tissue and cell type	KIF21A LPGAT1 XYLB SLC4A4 NR1H4	1.35e-04	187	117	5	d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCell	droplet-Kidney-nan-18m-Epithelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO6 KIF21A ARHGAP5 PTPRF SLC4A4	1.35e-04	187	117	5	236e9857729670e87eed30fad58f49e1f56e4a85
ToppCell	COVID-19-kidney-Mito-rich_PCT\|kidney / Disease (COVID-19 only), tissue and cell type	AGT XYLB SLC4A4 ANKRD33B NR1H4	1.35e-04	187	117	5	738ec2611b4be6a08eedad16b57fba84e1f11fef
ToppCell	droplet-Spleen-nan-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHX2 MYH10 ADAMTS13 XYLB NR1I3	1.39e-04	188	117	5	1a3f95b4fd7611c634666761ddf21f1e58e56af8
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	C1GALT1 NEGR1 QPCT CMAHP RPL10	1.39e-04	188	117	5	aa516273cdde53c8c0295f06830972388f890c97
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAPSN ARFGEF3 CLCNKB PROM2 ATP2B4	1.39e-04	188	117	5	ab6fa1beff91584d9303c2a33735de89aae8d5cd
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|RV / Chamber and Cluster_Paper	KIF21A OBSCN CBR4 MYOM2 VCL	1.42e-04	189	117	5	9c1debd65c13d63fd4f3158917d621b44b714c26
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIF21A ABCC6 XYLB SLC4A4 ANKRD33B	1.42e-04	189	117	5	204ab61ae606b2d9be0cb6bf6a83a011740693a8
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ABCC6 ARFGEF3 THRB PTPRF NEGR1	1.42e-04	189	117	5	7659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIF21A ABCC6 XYLB SLC4A4 ANKRD33B	1.42e-04	189	117	5	13fd07cc408a9486f61a7b2c3a132c52d14b438d
ToppCell	10x5'v1-week_14-16-Hematopoietic-HSC/MPP_and_pro-ELP\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MYCBP2 ATL1 USP2 NEGR1 RPL10	1.42e-04	189	117	5	46c3f3dff71e7131a5ad1cd3b68709051a474c3c
ToppCell	IPF-Epithelial-Club\|IPF / Disease state, Lineage and Cell class	MYO6 ARFGEF3 PROM2 SLC4A4 CMAHP	1.42e-04	189	117	5	f3fcef008ef252b29ac6d567fef27f9acf9cd70f
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-oRG/Astrocyte-7\|World / Primary Cells by Cluster	SLC25A18 FABP5 ARHGAP5 SLC15A2 AGT	1.46e-04	190	117	5	8f1c490dd8e5f80382f5294fd1aa8cba4c3c647f
ToppCell	PND28-Epithelial\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FABP5 PTPRF SLC15A2 CALML4 SPAG17	1.46e-04	190	117	5	89e5ddd830f70429d5b2fbaf8d0790b033450aa7
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH10 MYCBP2 PREX2 GLG1 CMAHP	1.46e-04	190	117	5	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
Drug	SR-12813	LDLR RXRB RXRG SCAP NR1I3	3.25e-07	29	115	5	CID000446313
Drug	AC1L3UEY	HUWE1 XRCC5 RXRB RXRG THRB NR1I3 NR1H4	1.73e-06	113	115	7	CID000122342
Drug	scoparone	RXRB RXRG NR1I3 NR1H4	7.20e-06	25	115	4	CID000008417
Drug	Atropine-N-oxide hydrochloride [4574-60-1]; Up 200; 11.8uM; PC3; HT_HG-U133A	ADCY2 LIPE THRB SLC15A2 SV2A CNGB3 MYOM2 NR1H4	7.59e-06	198	115	8	4476_UP
Drug	butylbenzyl phthalate	SIRT7 LDLR RXRB RXRG THRB NR1I3	1.83e-05	108	115	6	ctd:C027561
Drug	epicholesterol	EPHX2 ADCY2 LDLR RXRB RXRG FABP5 INTS10 LIPE SCAP THRB ATP2B4 NR1I3 NR1H4	2.01e-05	636	115	13	CID000000304
Drug	UVI 3003	RXRB RXRG THRB	2.01e-05	11	115	3	ctd:C525131
Drug	Bezafibrate	LDHA RXRB RXRG SCAP THRB AGT NR1I3 NR1H4	2.18e-05	229	115	8	ctd:D001629
Drug	AC1L3LFV	EPHX2 RXRB RXRG NR1H4	2.26e-05	33	115	4	CID000091134
Drug	di-n-propylphthalate	RXRB RXRG NR1I3	2.67e-05	12	115	3	ctd:C106479
Drug	desethylamiodarone	LDLR THRB AGT	3.46e-05	13	115	3	ctd:C036116
Disease	T-cell acute lymphoblastic leukemia (implicated_via_orthology)	RPL10L RPL10	4.35e-05	3	113	2	DOID:5603 (implicated_via_orthology)
Disease	1-oleoyl-2-docosapentaenoyl-GPC (18:1/22:5n3) measurement	SYCP2L RAPSN	4.35e-05	3	113	2	EFO_0800487
Disease	hypertrophic cardiomyopathy (is_implicated_in)	NDUFS2 AGT VCL	7.99e-05	22	113	3	DOID:11984 (is_implicated_in)
Disease	autistic disorder (implicated_via_orthology)	RPL10L RPL10	8.68e-05	4	113	2	DOID:12849 (implicated_via_orthology)
Disease	Hypercholesterolemia, familial, 1	EPHX2 LDLR	1.44e-04	5	113	2	cv:C0745103
Disease	HYPERCHOLESTEROLEMIA, FAMILIAL, 1	EPHX2 LDLR	1.44e-04	5	113	2	143890
Disease	Hyalinosis, Segmental Glomerular	MYH10 INF2 AGT	1.67e-04	28	113	3	C0086432
Disease	spondyloepiphyseal dysplasia congenita (implicated_via_orthology)	RPL10L RPL10	2.16e-04	6	113	2	DOID:14789 (implicated_via_orthology)
Disease	lysophosphatidylcholine 20:4 measurement	RAPSN MYCBP2 KCNJ6	2.50e-04	32	113	3	EFO_0010363
Disease	atherosclerosis (implicated_via_orthology)	LDLR AGT	3.01e-04	7	113	2	DOID:1936 (implicated_via_orthology)
Disease	syndromic X-linked intellectual disability Najm type (implicated_via_orthology)	RPL10L RPL10	3.01e-04	7	113	2	DOID:0060807 (implicated_via_orthology)
Disease	Focal glomerulosclerosis	MYH10 INF2 AGT	3.56e-04	36	113	3	C0017668
Disease	Hyperlipoproteinemia	EPHX2 LDLR	4.01e-04	8	113	2	cv:C0020476
Disease	Familial hypercholesterolemia	EPHX2 LDLR	4.01e-04	8	113	2	cv:C0020445
Disease	Myocardial Ischemia	EPHX2 RXRG FABP5 AGT UGCG	5.95e-04	176	113	5	C0151744
Disease	hereditary spastic paraplegia (implicated_via_orthology)	ATL1 CAPN11 AFG3L2	6.04e-04	43	113	3	DOID:2476 (implicated_via_orthology)
Disease	nephrogenic diabetes insipidus (implicated_via_orthology)	CLCNKB SLC4A4	6.41e-04	10	113	2	DOID:12387 (implicated_via_orthology)
Disease	familial hypercholesterolemia (is_implicated_in)	EPHX2 LDLR	6.41e-04	10	113	2	DOID:13810 (is_implicated_in)
Disease	cholestasis (biomarker_via_orthology)	ADAMTS13 NR1I3 NR1H4	8.86e-04	49	113	3	DOID:13580 (biomarker_via_orthology)
Disease	hyperinsulinism (is_implicated_in)	PTPRF AGT	9.36e-04	12	113	2	DOID:2018 (is_implicated_in)
Disease	anxiety disorder, stress-related disorder	ADCY2 CNGB3	9.36e-04	12	113	2	EFO_0006788, EFO_0010098
Disease	cholesteryl ester 24:5 measurement	SYCP2L RAPSN	9.36e-04	12	113	2	EFO_0021448
Disease	serum metabolite measurement	MYH10 RAPSN KIF26B LDHA LDLR ATP10D ATL1 PTCD1 SLC5A6 DNAH17 MYOM2	1.02e-03	945	113	11	EFO_0005653
Disease	Adenocarcinoma of lung (disorder)	ATR XRCC5 LDHA SLC15A2 SLC4A4	1.20e-03	206	113	5	C0152013
Disease	hypertension (is_implicated_in)	EPHX2 LIPE CLCNKB AGT	1.23e-03	121	113	4	DOID:10763 (is_implicated_in)
Disease	sex interaction measurement, longitudinal BMI measurement, age at assessment	GXYLT1 SLCO5A1	1.28e-03	14	113	2	EFO_0005937, EFO_0008007, EFO_0008343
Disease	phoneme awareness	ZNFX1 KCNJ6	1.28e-03	14	113	2	EFO_0021812
Disease	YKL40 measurement	PPFIA4 ATP2B4	1.48e-03	15	113	2	EFO_0004869
Disease	level of Phosphatidylcholine (16:0_16:0) in blood serum	RAPSN LDLR	1.48e-03	15	113	2	OBA_2045067
Disease	Parkinson disease	LAMTOR2 MYCBP2 GXYLT1 DNAH17 ANKRD33B RPL10	1.51e-03	321	113	6	MONDO_0005180
Disease	hypertension (implicated_via_orthology)	EPHX2 MYO6 EGLN1 AGT	1.51e-03	128	113	4	DOID:10763 (implicated_via_orthology)
Disease	Atherosclerosis	LDLR AGT NR1H4	1.52e-03	59	113	3	C0004153
Disease	Atherogenesis	LDLR AGT NR1H4	1.52e-03	59	113	3	C1563937
Disease	Cardiomyopathies	LDHA NDUFS2 AGT VCL	1.60e-03	130	113	4	C0878544
Disease	free cholesterol in very large VLDL measurement	RAPSN LDLR INTS10	1.67e-03	61	113	3	EFO_0022274
Disease	Hyperlipoproteinemia Type IIa	EPHX2 LDLR	1.68e-03	16	113	2	C0745103
Disease	cholesterol in very large VLDL measurement	RAPSN LDLR INTS10	2.01e-03	65	113	3	EFO_0022230
Disease	red blood cell density measurement	RAPSN ATR EGLN1 ABCC6 ARID1B THRB PTPRF CLCNKB UGCG ATP2B4	2.07e-03	880	113	10	EFO_0007978
Disease	free cholesterol in large VLDL measurement	RAPSN LDLR INTS10	2.29e-03	68	113	3	EFO_0022265
Disease	sodium-coupled monocarboxylate transporter 1 measurement	RAPSN LDLR	2.38e-03	19	113	2	EFO_0802076
Disease	Cardiomyopathies, Primary	LDHA NDUFS2 AGT	2.38e-03	69	113	3	C0033141
Disease	Myocardial Diseases, Secondary	LDHA NDUFS2 AGT	2.38e-03	69	113	3	C0036529
Disease	cholesteryl esters to total lipids in very small VLDL percentage	RAPSN LDLR INTS10	2.59e-03	71	113	3	EFO_0022259
Disease	JT interval	RAPSN OBSCN THRB MYOM2 SLC4A4	2.71e-03	248	113	5	EFO_0007885
Disease	Kidney Failure	INF2 AGT	3.19e-03	22	113	2	C0035078
Disease	Liver carcinoma	ADAMTS13 FABP5 USP2 ARID1B SCAP KDM8 NR1H4	3.43e-03	507	113	7	C2239176
Disease	Disease Exacerbation	CCT7 ABCC6 RXRB PTPRF	3.78e-03	165	113	4	C0235874
Disease	lysophosphatidylcholine 18:0 measurement	RAPSN KCNJ6	3.80e-03	24	113	2	EFO_0010359

Protein segments in the cluster

Peptide	Gene	Start	Entry
LLDMLDLTCAMKSSG	BRD1	721	O95696
MANKRCLDMEGRIKT	AMOT	736	Q4VCS5
GDERAMAKELASLLC	AVIL	561	O75366
IKATDLMVAMRCLGA	CALML4	71	Q96GE6
LLDRMCMTLGGRVSE	AFG3L2	621	Q9Y4W6
DRKNPVCREMSMALL	ARID1B	2191	Q8NFD5
VLKLLAEMSSFCGDM	API5	286	Q9BZZ5
GLDACRCMINLMDKD	CAPN11	611	Q9UMQ6
AMLKGLCEMSVESLN	CD180	266	Q99467
DFGCTVMELRKLMEL	ATP2B4	21	P23634
KDACGMLMSTILKEL	ATP10D	951	Q9P241
MCRAIGESFIMKRGD	ADAMTS13	486	Q76LX8
GLMELRFLCMDSALR	ADAMTS13	911	Q76LX8
REAGIMLSDDVCQLM	CAPN14	616	A8MX76
LDTEDKLRAAMVGML	AGT	86	P01019
KAAMQGRTDCIRALM	ANKRD33B	196	A6NCL7
RLGSAMECCEESMKI	RAPSN	221	Q13702
AVPCAMMLELARALD	QPCT	161	Q16769
LGEYRMTCEKVLDLM	INTS10	506	Q9NVR2
MSLLGKLVSMAVAVC	INTS15	111	Q96N11
ECRLRKCKEMGMLAE	NR1H4	191	Q96RI1
VGMACAISILMKDLA	LDHA	31	P00338
CLDAGMRKDMILSAE	NR1I3	71	Q14994
LQRLLDGRKMCKDME	PSTPIP1	26	O43586
MELTSLCGDDTMRLL	ITPK1	131	Q13572
DVCTLMMCLQDKGLV	LPGAT1	106	Q92604
DNMMVRKGDTAVLRC	NEGR1	46	Q7Z3B1
KGEMEGEALLSCLAM	FER1L6-AS1	21	Q8NA97
ISMRDGKLCLMFRVG	KCNJ6	211	P48051
MECLVDARMLDHLTK	PPFIA4	966	O75335
KLAMLLRESLGNMNC	KIF26B	756	Q2KJY2
AVAKDRMMLQECRGT	FAM184B	326	Q9ULE4
LHMQELCEGMKLLAS	IKBKE	681	Q14164
VAAALRVCDMGLLMG	KDM8	116	Q8N371
MTELGCDSMEKLKAL	DCUN1D2	126	Q6PH85
GFISCKDLGNLMRTM	CABP5	46	Q9NP86
EAVMSRGLCVQLMAL	OR14K1	131	Q8NGZ2
VACGERLEETMTMLK	GXYLT1	121	Q4G148
CGLTTADMKEMVALL	LRRC31	96	Q6UY01
DFAARCGMILQEAMK	PI4KA	1056	P42356
QGSCAKLMLRTGLLM	LRRC37B	836	Q96QE4
KGRLMTCSLDLDSEM	FAAP100	426	Q0VG06
EALVSCGMMEALLKV	HUWE1	401	Q7Z6Z7
ALRKMGAMAKPDCII	FABP5	31	Q01469
MLLCEGAAAVLDMVR	INF2	721	Q27J81
MVLSGALCFRMKDSA	IL36RN	1	Q9UBH0
RLVMELSGEMVRKCD	NDUFS2	96	O75306
KLDPDMALCRNAREM	PLOD2	486	O00469
MCELQIRGLAMVDAA	OBSCN	3326	Q5VST9
DMLEKAAELLMSCFR	PCID2	136	Q5JVF3
RGRQMSCLMEALEDK	GLG1	1086	Q92896
MGLDMCEAIKKVRDA	ADCY2	361	Q08462
CVMFEDGVLMRLKSD	ATR	326	Q13535
MFEGREIKLVMTCAA	DNAH6	1556	Q9C0G6
AERDGLAQLMCELKM	EPHX2	131	P34913
EMKRFALTLVMGALE	HEATR5A	846	Q86XA9
DIIASLCNMIMGLTL	ATL1	471	Q8WXF7
LADLEAFMKVARMGL	DNAH17	1096	Q9UFH2
CEIMLMAEGFLEARL	DNAH17	1981	Q9UFH2
KGMIDCLMKTARAEG	SLC25A18	46	Q9H1K4
LDLLKLIMDGMTEAC	ARFGEF3	401	Q5TH69
TNLLGSMLTCKAAMR	CBR4	106	Q8N4T8
MSCLMRKDVLDQAGG	UGCG	211	Q16739
CETIGLLMSSMDDLI	EGLN1	266	Q9GZT9
EDNLKFILMDCMEGR	LAMTOR2	66	Q9Y2Q5
SSIEDLALGRCMEIM	C1GALT1	236	Q9NS00
ELREMDCSVLKRLMN	DUSP4	6	Q13115
SLRKMAVGMILACLA	SLC15A2	376	Q16348
LMDIECLASDGMLLV	SCAP	776	Q12770
MDGKQACERMIRALE	MYH10	741	P35580
CALDPMLDDSVMLAR	LIPE	991	Q05469
GCFIVIDAMLERMKH	PTPRF	1556	P10586
KMLSCAGADRLQTGM	RPL10L	101	Q96L21
EMCLRFADMECKLGE	XAB2	666	Q9HCS7
RSVMDCARVLVMDKG	ABCC6	1461	O95255
KMLSCAGADRLQTGM	RPL10	101	P27635
MADRKMGCLPVALSL	SLC5A6	61	Q9Y289
MGILRDKESGICMDS	SCRN2	266	Q96FV2
LKLGARESAKLAMIC	SLCO5A1	496	Q9H2Y9
MRNCKMARVASVLGL	ST8SIA3	1	O43173
DELLASMMAGVKCRL	TELO2	381	Q9Y4R8
EEDLKRTMMACGGSI	CCT7	316	Q99832
LGCLDTLAAMQDLKM	MYCBP2	1196	O75592
KDLSEADLRIVMCAM	ARHGAP5	771	Q13017
LHGKCDDVMRLLMAE	SIRT7	311	Q9NRC8
MMLKLGTDIFENIAC	SPAG17	336	Q6Q759
DMCLSDSNKGMLGLI	SV2A	196	Q7L0J3
MRMDKTELGCLRAII	RXRB	431	P28702
SGKRICLGEAMARME	CYP2G1P	86	Q6ZSU1
ACMDLKLGDKRMVFD	CMAHP	41	Q9Y471
LGVLMALVSCAMDLA	CLCNKB	56	P51801
KGCDTQMIYDMLLRL	CNGB3	526	Q9NQW8
GAMKHQLLCDLMDLI	C11orf40	126	Q8WZ69
CAILDMERDTLMLSG	TBC1D17	531	Q9HA65
SRMLCAGIMSGKRDA	TMPRSS7	771	Q7RTY8
GALDNSRVILCDMMA	PROM2	761	Q8N271
RLSKMVEDACMLLAD	RPRD1A	211	Q96P16
MMQCLKLGALSRTTA	KIF21A	201	Q7Z4S6
MLESADGKICLVMEL	TSSK3	76	Q96PN8
LSEGMCHLMKDLART	SYCP2L	206	Q5T4T6
LLMKVTDLRMIGACH	THRB	421	P10828
MALLCFKNGSLMREK	XYLB	331	O75191
DIIAAAKRMALLMAE	VCL	986	P18206
MEEAGLCGLREKADM	TXLNGY	1	Q9BZA5
SAMAELTDLGKCLMK	XPO5	1006	Q9HAV4
MQMDKSELGCLRAIV	RXRG	361	P48443
DTCTEMLMCGVLLKI	PREX2	241	Q70Z35
EDLCSKFGMDLKRGM	MRPL28	151	Q13084
GMLLASCSDDMTLKI	TBL1Y	371	Q9BQ87
KEMYSLCLLATLMGE	VCPIP1	891	Q96JH7
AKMLLAMRLDHCGTG	ZNFX1	861	Q9P2E3
RMKDSLICLDCAMES	USP41	171	Q3LFD5
LRTCMEKGSIMLDRE	SLC4A4	161	Q9Y6R1
MAAKCADLRMCLDVF	PTCD1	256	O75127
MDCMRLFTKEDVLDG	USP2	456	O75604
MDVSAVLMGLLELCA	WDR7	1216	Q9Y4E6
MVRSGNKAAVVLCMD	XRCC5	1	P13010
GMLLARDMRSCLTEA	LDLR	701	P01130
LVAGKDDMEMCELNL	MYO6	1226	Q9UM54
DDMILAMSRVCGKSA	MYOM2	1221	P54296