Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionchloride:monoatomic cation symporter activity

SLC6A3 SLC12A1 SLC12A3 SLC12A9

3.52e-05231654GO:0015377
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLCO4A1 SLC34A2 SLC7A6 SLCO1B7 SLC6A3 SLC12A1 SLC12A3 SLC12A9 SLC35D3 SLC9A7 SLC26A6

3.68e-0529616511GO:0015291
GeneOntologyMolecularFunctionactive transmembrane transporter activity

ABCC1 ABCB5 SLCO4A1 SLC34A2 SLC7A6 SLCO1B7 SLC6A3 SLC12A1 SLC12A3 SLC12A9 SLC35D3 SLC9A7 ATP4B SLC26A6

4.39e-0547716514GO:0022804
GeneOntologyMolecularFunctionpotassium:chloride symporter activity

SLC12A1 SLC12A3 SLC12A9

4.49e-0591653GO:0015379
GeneOntologyMolecularFunctionmonoatomic anion:monoatomic cation symporter activity

SLC6A3 SLC12A1 SLC12A3 SLC12A9

5.83e-05261654GO:0015296
GeneOntologyMolecularFunctionsodium:potassium:chloride symporter activity

SLC12A1 SLC12A3

2.03e-0431652GO:0008511
GeneOntologyMolecularFunctionpotassium:sodium symporter activity

SLC12A1 SLC12A3

2.03e-0431652GO:0009674
GeneOntologyMolecularFunctionefflux transmembrane transporter activity

ABCC1 ABCB5 SLC26A6

2.87e-04161653GO:0015562
GeneOntologyMolecularFunctionsodium:chloride symporter activity

SLC6A3 SLC12A1 SLC12A3

3.46e-04171653GO:0015378
GeneOntologyMolecularFunctionFAD binding

DPYD AIFM1 CYB5R3 CYB5R1

4.72e-04441654GO:0071949
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

SLC12A1 SLC12A3 SLC12A9 KCNK1 SLC9A7 KCNN4 ATP4B

4.85e-041671657GO:0015079
GeneOntologyMolecularFunctionmonoatomic anion:sodium symporter activity

SLC6A3 SLC12A1 SLC12A3

4.87e-04191653GO:0015373
GeneOntologyMolecularFunctionGTPase activator activity

ARHGAP42 DOCK4 ARHGAP23 MYO9A TIAM2 SYNGAP1 PLEKHG6 USP6NL RASAL1

5.36e-042791659GO:0005096
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

ABCC1 SLC34A2 SLC6A3 SLC12A1 SLC12A3 SLC12A9 SLC26A6

5.59e-041711657GO:0015103
GeneOntologyMolecularFunctionATPase inhibitor activity

FNIP2 FNIP1

9.96e-0461652GO:0042030
GeneOntologyMolecularFunctionATPase regulator activity

FNIP2 GTF2H4 FNIP1 ATP4B

1.03e-03541654GO:0060590
GeneOntologyMolecularFunctionflavin adenine dinucleotide binding

DPYD GSR AIFM1 CYB5R3 CYB5R1

1.10e-03941655GO:0050660
GeneOntologyMolecularFunctionalkali metal ion binding

ACAT1 SLC34A2 PKLR

1.25e-03261653GO:0031420
GeneOntologyMolecularFunctioncytochrome-b5 reductase activity, acting on NAD(P)H

CYB5R3 CYB5R1

1.39e-0371652GO:0004128
GeneOntologyMolecularFunctionamidine-lyase activity

PAM GGACT

1.39e-0371652GO:0016842
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

SLC6A3 SLC12A1 SLC12A3 SLC12A9 SLC26A6 VDAC3

1.62e-031511656GO:0008509
GeneOntologyMolecularFunctiontransmembrane transporter activity

CACNA1F ABCC1 ABCB5 MFSD9 SLCO4A1 SLC34A2 SLC7A6 SLCO1B7 SLC6A3 SLC12A1 SLC12A3 SLC12A9 SLC35D3 KCNK1 SLC9A7 KCNN4 AP4M1 ATP4B SLC26A6 VDAC3

1.79e-03118016520GO:0022857
GeneOntologyMolecularFunctioncobalt ion binding

NUDT16 RNPEP

1.84e-0381652GO:0050897
GeneOntologyBiologicalProcessneuron projection development

BOC CACNA1F KLHL1 FN1 KIF26A MYO9A TNC FAT3 LAMA2 APLP2 ZSWIM6 ADGRV1 TIAM2 MKS1 SEMA4C SYNGAP1 GRIP1 POSTN HMCN2 MAP1S TRIM32 CLMN P3H1 CSPG4 ACTL6B TNR DCLK1 RASAL1

1.04e-06128516428GO:0031175
GeneOntologyBiologicalProcessneuron development

BOC CACNA1F KLHL1 FN1 KIF26A MYO9A TNC FAT3 LAMA2 APLP2 ZSWIM6 ADGRV1 TIAM2 MKS1 SEMA4C SYNGAP1 GRIP1 POSTN HMCN2 MAP1S TRIM32 CLMN P3H1 CSPG4 ACTL6B GRIP2 TNR DCLK1 RASAL1

4.29e-06146316429GO:0048666
GeneOntologyCellularComponentplatelet alpha granule

A2M FN1 APLP2 F5 F8 CYB5R1

9.87e-05931666GO:0031091
GeneOntologyCellularComponentprotein complex involved in cell-matrix adhesion

TNC LAMA2 TNR

3.08e-04171663GO:0098637
GeneOntologyCellularComponentendoplasmic reticulum lumen

PNPLA2 FN1 TNC APLP2 F5 F8 ARSH ADAMTS7 P3H1 CERCAM

3.33e-0433216610GO:0005788
GeneOntologyCellularComponenttenascin complex

TNC TNR

3.72e-0441662GO:0090733
MousePhenoabnormal heart left ventricle morphology

ADAMTS19 PNPLA2 ZMPSTE24 SYNM DSP ATAD5 OXA1L HMCN2 AARS2 AIFM1 KCNN4 FNIP1 TBX20 GAA

7.10e-0636912814MP:0003921
MousePhenoabnormal axon radial sorting

MPZ LAMA2 SBF1

7.40e-0651283MP:0020452
DomainNNMT/PNMT/TEMT_CS

PNMT INMT NNMT

6.77e-0731653IPR025820
DomainNNMT_TEMT_trans

PNMT INMT NNMT

6.77e-0731653IPR000940
DomainSAM_MT_NNMT_PNMT_TEMT

PNMT INMT NNMT

6.77e-0731653PS51681
DomainNNMT_PNMT_TEMT

PNMT INMT NNMT

6.77e-0731653PF01234
DomainNNMT_PNMT_TEMT

PNMT INMT NNMT

6.77e-0731653PS01100
DomainSLC12_C

SLC12A1 SLC12A3 SLC12A9

3.67e-0581653IPR018491
DomainSLC12

SLC12A1 SLC12A3 SLC12A9

3.67e-0581653PF03522
DomainAA-permease/SLC12A_dom

SLC7A6 SLC12A1 SLC12A3 SLC12A9

3.79e-05221654IPR004841
DomainAA_permease

SLC7A6 SLC12A1 SLC12A3 SLC12A9

3.79e-05221654PF00324
DomainFNIP_N_dom

FNIP2 FNIP1

7.76e-0521652IPR028084
DomainFNIP_mid_dom

FNIP2 FNIP1

7.76e-0521652IPR028085
DomainFNIP_C_dom

FNIP2 FNIP1

7.76e-0521652IPR028086
DomainPr_beta_C

PSMB7 PSMB10

7.76e-0521652PF12465
DomainFNIP_C

FNIP2 FNIP1

7.76e-0521652PF14638
DomainFNIP_M

FNIP2 FNIP1

7.76e-0521652PF14637
DomainFNIP_N

FNIP2 FNIP1

7.76e-0521652PF14636
DomainFactor_5/8

F5 F8

7.76e-0521652IPR024715
DomainFNIP_fam

FNIP2 FNIP1

7.76e-0521652IPR026156
DomainProteasome_bsu_C

PSMB7 PSMB10

7.76e-0521652IPR024689
DomainAA_permease_N

SLC12A1 SLC12A3

2.31e-0431652IPR013612
DomainAA_permease_N

SLC12A1 SLC12A3

2.31e-0431652PF08403
DomainFN3_dom

BOC FN1 TNC IL20RA PTPRT TRIL MDGA1 TNR

5.50e-042091658IPR003961
DomainPyr_redox_2

DPYD GSR AIFM1

5.91e-04191653PF07992
DomainConA-like_dom

TRIM26 FAT3 LAMA2 ADGRV1 PTPRT BTNL3 CSPG4 MDGA1

7.47e-042191658IPR013320
DomainNADH-Cyt_B5_reductase

CYB5R3 CYB5R1

7.62e-0451652IPR001834
DomainCu-oxidase_3

F5 F8

7.62e-0451652IPR011707
DomainMULTICOPPER_OXIDASE1

F5 F8

7.62e-0451652PS00079
DomainFAD_binding_6

CYB5R3 CYB5R1

7.62e-0451652PF00970
DomainCu_oxidase_CS

F5 F8

7.62e-0451652IPR033138
DomainOxRdtase_FAD-bd_dom

CYB5R3 CYB5R1

7.62e-0451652IPR008333
DomainCu-oxidase_3

F5 F8

7.62e-0451652PF07732
DomainCupredoxin

F5 F8 PADI1

9.22e-04221653IPR008972
DomainRho_GTPase_activation_prot

ARHGAP42 ARHGAP23 MYO9A SYNGAP1 RASAL1

1.10e-03881655IPR008936
DomainCu_oxidase_Cu_BS

F5 F8

1.14e-0361652IPR002355
PathwayWP_METHYLATION_PATHWAYS

PNMT INMT NNMT

6.32e-0591313M39493
PathwayWP_METHYLATION

PNMT INMT NNMT

6.32e-0591313MM15836
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

A2M FN1 TNC LAMA2 PGLYRP2 F5 F8 POSTN CSPG4 C5 MDGA1 GAA

4.88e-092571671216335952
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

FN1 ARHGAP23 MYO9A TNC VPS13C SORBS1 ADGRV1 GRIP1 SBF1 TRIM32 PAM PNPLA8 TNR VDAC3

2.44e-084301671432581705
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

ZMPSTE24 FN1 ACAT1 DSP VPS13C FUZ ADGRV1 TIAM2 GSR ADH6 SLC12A1 SLC12A3 RNPEP SLC12A9 P3H1 PKLR C5 AP4M1 GAA VDAC3

1.06e-0710161672019056867
Pubmed

Human indolethylamine N-methyltransferase: cDNA cloning and expression, gene cloning, and chromosomal localization.

PNMT INMT NNMT

1.09e-073167310552930
Pubmed

The proteoglycan NG2 is complexed with alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors by the PDZ glutamate receptor interaction protein (GRIP) in glial progenitor cells. Implications for glial-neuronal signaling.

GRIP1 CSPG4 GRIP2

4.33e-074167312458226
Pubmed

Hemicentin-1 is an essential extracellular matrix component of the dermal-epidermal and myotendinous junctions.

TNC LAMA2 HMCN2

4.33e-074167334504132
Pubmed

A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.

LAMA2 GRIP1 CSPG4 GRIP2

1.49e-0618167414730302
Pubmed

DLL4 promotes continuous adult intestinal lacteal regeneration and dietary fat transport.

FN1 TNC POSTN CSPG4

2.88e-0621167426529256
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

TACO1 ABCC1 FN1 ARHGAP23 DSP GSR LMF2 OXA1L AARS2 SBF1 AIFM1 P3H1 DHRS7 CSPG4 CYB5R3 PAM CERCAM CFAP44 CATSPERG USP6NL GAA

6.90e-0614511672130550785
Pubmed

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.

FN1 TNC LAMA2 POSTN HMCN2 RNPEP CSPG4

7.19e-06146167727068509
Pubmed

Cation-chloride cotransporters and neuronal function.

SLC12A1 SLC12A3 SLC12A9

8.94e-069167319323993
Pubmed

Expression of laminin alpha1, alpha2, alpha4, and alpha5 chains, fibronectin, and tenascin-C in skeletal muscle of dystrophic 129ReJ dy/dy mice.

FN1 TNC LAMA2

8.94e-06916739882526
Pubmed

Twist1 transcriptional targets in the developing atrio-ventricular canal of the mouse.

ADAMTS19 POSTN TBX20

1.74e-0511167322815831
Pubmed

Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling.

FAT3 APLP2 CDC37 AIFM1 DCHS1

1.83e-0567167521875946
Pubmed

Desmopressin acetate as a haemostatic elevator in individuals with combined deficiency of factors V and VIII: a clinical trial.

F5 F8

2.29e-052167226599105
Pubmed

The molecular basis of factor V and VIII procofactor activation.

F5 F8

2.29e-052167219765210
Pubmed

Tenascins and inflammation in disorders of the nervous system.

TNC TNR

2.29e-052167223269478
Pubmed

Upregulation of SLC12A3 and SLC12A9 Mediated by the HCP5/miR-140-5p Axis Confers Aggressiveness and Unfavorable Prognosis in Uveal Melanoma.

SLC12A3 SLC12A9

2.29e-052167236925204
Pubmed

The glutamate receptor-interacting protein family of GluR2-binding proteins is required for long-term synaptic depression expression in cerebellar Purkinje cells.

GRIP1 GRIP2

2.29e-052167218509036
Pubmed

Factor VIII/V C-domain swaps reveal discrete C-domain roles in factor VIII function and intracellular trafficking.

F5 F8

2.29e-052167228057741
Pubmed

Staphylococcal superantigen-like protein 8 (SSL8) binds to tenascin C and inhibits tenascin C-fibronectin interaction and cell motility of keratinocytes.

FN1 TNC

2.29e-052167223485472
Pubmed

[Correlation between clinicopathological factors and enzymatic activity of orotate phosphoribosyl transferase (OPRT), dihydropyrimidine dehydrogenase (DPD) in esophageal cancer].

DPYD UMPS

2.29e-052167220647710
Pubmed

Molecular cloning of the mouse proteasome subunits MC14 and MECL-1: reciprocally regulated tissue expression of interferon-gamma-modulated proteasome subunits.

PSMB7 PSMB10

2.29e-05216729174609
Pubmed

Fibronectin and Periostin as Prognostic Markers in Ovarian Cancer.

FN1 POSTN

2.29e-052167231936272
Pubmed

The factor VIII D1241E polymorphism is associated with decreased factor VIII activity and not with activated protein C resistance levels.

F5 F8

2.29e-052167215735794
Pubmed

Counterbalancing anti-adhesive effects of Tenascin-C through fibronectin expression in endothelial cells.

FN1 TNC

2.29e-052167228986537
Pubmed

Increased factor VIII coagulant activity levels in male carriers of the factor V R2 polymorphism.

F5 F8

2.29e-052167217287628
Pubmed

Purkinje cell-specific Grip1/2 knockout mice show increased repetitive self-grooming and enhanced mGluR5 signaling in cerebellum.

GRIP1 GRIP2

2.29e-052167231476380
Pubmed

Urinary exosomes in the diagnosis of Gitelman and Bartter syndromes.

SLC12A1 SLC12A3

2.29e-052167225422309
Pubmed

Periostin and matrix stiffness combine to regulate myofibroblast differentiation and fibronectin synthesis during palatal healing.

FN1 POSTN

2.29e-052167232777343
Pubmed

Opposite impacts of tenascin-C and tenascin-R deficiency in mice on the functional outcome of facial nerve repair.

TNC TNR

2.29e-052167216262655
Pubmed

Tenascins are associated with lipid rafts isolated from mouse brain.

TNC TNR

2.29e-052167212056833
Pubmed

Activated protein C has a regulatory role in factor VIII function.

F5 F8

2.29e-052167233512448
Pubmed

The Extracellular Matrix Proteins Tenascin-C and Tenascin-R Retard Oligodendrocyte Precursor Maturation and Myelin Regeneration in a Cuprizone-Induced Long-Term Demyelination Animal Model.

TNC TNR

2.29e-052167235681468
Pubmed

Both gene expression for orotate phosphoribosyltransferase and its ratio to dihydropyrimidine dehydrogenase influence outcome following fluoropyrimidine-based chemotherapy for metastatic colorectal cancer.

DPYD UMPS

2.29e-052167214562021
Pubmed

Factor XIII Val34Leu and the risk of venous thromboembolism in factor V Leiden carriers.

F5 F8

2.29e-052167211091190
Pubmed

Cleavage of extracellular matrix in periodontitis: gingipains differentially affect cell adhesion activities of fibronectin and tenascin-C.

FN1 TNC

2.29e-052167223313574
Pubmed

Cryptic domains of tenascin-C differentially control fibronectin fibrillogenesis.

FN1 TNC

2.29e-052167220708078
Pubmed

Incorporation of tenascin-C into the extracellular matrix by periostin underlies an extracellular meshwork architecture.

TNC POSTN

2.29e-052167219887451
Pubmed

Binding of tenascin-C to soluble fibronectin and matrix fibrils.

FN1 TNC

2.29e-05216727499434
Pubmed

Disruption of glutamate receptor-interacting protein in nucleus accumbens enhances vulnerability to cocaine relapse.

GRIP1 GRIP2

2.29e-052167224126453
Pubmed

Mice lacking GRIP1/2 show increased social interactions and enhanced phosphorylation at GluA2-S880.

GRIP1 GRIP2

2.29e-052167228063882
Pubmed

Tenascin C, Fibronectin, and Tumor-Stroma Ratio in Pancreatic Ductal Adenocarcinoma.

FN1 TNC

2.29e-052167230451798
Pubmed

Periostin and tenascin-C interaction promotes angiogenesis in ischemic proliferative retinopathy.

TNC POSTN

2.29e-052167232518264
Pubmed

Conservative mutations in the C2 domains of factor VIII and factor V alter phospholipid binding and cofactor activity.

F5 F8

2.29e-052167222613792
Pubmed

Cleft palate formation in fetal Br mice with midfacial retrusion: tenascin, fibronectin, laminin, and type IV collagen immunolocalization.

FN1 TNC

2.29e-05216729482226
Pubmed

De novo expression of fetal ED-A(+) fibronectin and B (+) tenascin-C splicing variants in human cardiac allografts: potential impact for targeted therapy of rejection.

FN1 TNC

2.29e-052167224792713
Pubmed

GRIP1 and 2 regulate activity-dependent AMPA receptor recycling via exocyst complex interactions.

GRIP1 GRIP2

2.29e-052167220956289
Pubmed

From Fish Physiology to Human Disease: The Discovery of the NCC, NKCC2, and the Cation-Coupled Chloride Cotransporters.

SLC12A1 SLC12A3

2.29e-052167237968800
Pubmed

Fatal haemorrhage and incomplete block to embryogenesis in mice lacking coagulation factor V.

F5 C5

2.29e-05216728900278
Pubmed

Changes in extra cellular matrix remodelling and re-expression of fibronectin and tenascin-C splicing variants in human myocardial tissue of the right atrial auricle: implications for a targeted therapy of cardiovascular diseases using human SIP format antibodies.

FN1 TNC

2.29e-052167220232238
Pubmed

Tenascin C and tenascin R similarly prevent the formation of myelin membranes in a RhoA-dependent manner, but antagonistically regulate the expression of myelin basic protein via a separate pathway.

TNC TNR

2.29e-052167219459213
Pubmed

Gene targeting of GAN in mouse causes a toxic accumulation of microtubule-associated protein 8 and impaired retrograde axonal transport.

MAP1S GAN

2.29e-052167216565160
Pubmed

Molecular cloning, primary structure, and characterization of two members of the mammalian electroneutral sodium-(potassium)-chloride cotransporter family expressed in kidney.

SLC12A1 SLC12A3

2.29e-05216728021284
Pubmed

New candidate genes identified for controlling mouse gonadal sex determination and the early stages of granulosa and Sertoli cell differentiation.

DOCK4 TBX20 MAP3K21 DCLK1

4.10e-0540167419864314
Pubmed

Scleraxis is required for cell lineage differentiation and extracellular matrix remodeling during murine heart valve formation in vivo.

TNC POSTN TBX20

4.74e-0515167318802027
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

FN1 SYNM DSP FUZ OAZ1 SORBS1 TM2D3 REV3L SYNGAP1 RBM22 MAP1S TRIM32 PDE4DIP CERCAM EXOC7 BACE2 LNX1 DCLK1

4.99e-0512851671835914814
Pubmed

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

A2M FN1 TNC LAMA2 POSTN CSPG4

5.05e-05135167628675934
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

ABCC1 PSMB7 APLP2 SEMA4C LMF2 AARS2 SLC12A9 TRIM32 P3H1 DHRS7 UTP20 UMPS EXOC7 GAA VDAC3

5.33e-059421671531073040
Pubmed

Mechanical loading is required for initiation of extracellular matrix deposition at the developing murine myotendinous junction.

TNC LAMA2 POSTN

5.82e-0516167336709857
Pubmed

The transcription factor grainyhead-like 2 regulates the molecular composition of the epithelial apical junctional complex.

GRHL1 SLC12A1 SLC12A3

5.82e-0516167320978075
Pubmed

Comprehensive proteomic characterization of stem cell-derived extracellular matrices.

A2M FN1 TNC POSTN P3H1

6.12e-0586167528327460
Pubmed

Cardiovascular expression of the mouse WNK1 gene during development and adulthood revealed by a BAC reporter assay.

SLC12A1 SLC12A3

6.85e-053167216816365
Pubmed

Dominance of intrinsic genetic factors in shaping the human immunoglobulin Vlambda repertoire.

EXOC7 SLC26A6

6.85e-053167210610771
Pubmed

Tenascin-C, tenascin-R and tenascin-X: a family of talented proteins in search of functions.

TNC TNR

6.85e-05316727694605
Pubmed

Metastatic outgrowth encompasses COL-I, FN1, and POSTN up-regulation and assembly to fibrillar networks regulating cell adhesion, migration, and growth.

FN1 POSTN

6.85e-053167220489157
Pubmed

Factor V Leiden improves in vivo hemostasis in murine hemophilia models.

F5 F8

6.85e-053167216359510
Pubmed

Epithelial-mesenchymal interactions in the developing kidney lead to expression of tenascin in the mesenchyme.

FN1 TNC

6.85e-05316722440899
Pubmed

Periostin, tenascin, osteopontin isoforms in long- and non-long survival patients with pancreatic cancer: a pilot study.

TNC POSTN

6.85e-053167232886326
Pubmed

GRIP1 is required for homeostatic regulation of AMPAR trafficking.

GRIP1 GRIP2

6.85e-053167226216979
Pubmed

Coagulation procofactor activation by factor XIa.

F5 F8

6.85e-053167220456758
Pubmed

Contributions of rare coding variants in hypotension syndrome genes to population blood pressure variation.

SLC12A1 SLC12A3

6.85e-053167230113482
Pubmed

Downregulation of NCC and NKCC2 cotransporters by kidney-specific WNK1 revealed by gene disruption and transgenic mouse models.

SLC12A1 SLC12A3

6.85e-053167221131289
Pubmed

Factor V Leiden mutation and high FVIII are associated with an increased risk of VTE in women with breast cancer during adjuvant tamoxifen - results from a prospective, single center, case control study.

F5 F8

6.85e-053167225592075
Pubmed

Reduced extracellular space in the brain of tenascin-R- and HNK-1-sulphotransferase deficient mice.

TNC TNR

6.85e-053167216262627
Pubmed

Physiology of SLC12 transporters: lessons from inherited human genetic mutations and genetically engineered mouse knockouts.

SLC12A1 SLC12A9

6.85e-053167223325410
Pubmed

Tenascin during gut development: appearance in the mesenchyme, shift in molecular forms, and dependence on epithelial-mesenchymal interactions.

FN1 TNC

6.85e-05316722461951
Pubmed

Expression of dihydropyrimidine dehydrogenase, orotate phosphoribosyl transferase and thymidylate synthase in patients with primary colorectal cancer, and associations with site of first metastasis.

DPYD UMPS

6.85e-053167222641663
Pubmed

Gain-of-function glutamate receptor interacting protein 1 variants alter GluA2 recycling and surface distribution in patients with autism.

GRIP1 GRIP2

6.85e-053167221383172
Pubmed

Microdissection is essential for gene expression analysis of irradiated rectal cancer tissues.

DPYD UMPS

6.85e-053167219724871
Pubmed

Isolation and characterization of fibronectin-alpha 1-microglobulin complex in rat plasma.

A2M FN1

6.85e-05316727519849
Pubmed

Expression of tenascin in developing and adult mouse lymphoid organs.

FN1 TNC

6.85e-05316727687262
Pubmed

Interaction of syntenin-1 and the NG2 proteoglycan in migratory oligodendrocyte precursor cells.

GRIP1 CSPG4

6.85e-053167218218632
Pubmed

Interpretation of correlations between coagulation factors FV, FVIII and vWF in normal and type 2 diabetes mellitus patients.

F5 F8

6.85e-053167222032085
Pubmed

Co-segregation of thrombophilic disorders in factor V Leiden carriers; the contributions of factor VIII, factor XI, thrombin activatable fibrinolysis inhibitor and lipoprotein(a) to the absolute risk of venous thromboembolism.

F5 F8

6.85e-053167212368162
Pubmed

The tenascin gene family.

TNC TNR

6.85e-05316727530141
Pubmed

Serine 62 is a phosphorylation site in folliculin, the Birt-Hogg-Dubé gene product.

FNIP2 FNIP1

6.85e-053167219914239
Pubmed

Non-association of the thiazide-sensitive Na,Cl-cotransporter gene with polygenic hypertension in both rats and humans.

SLC12A1 SLC12A3

6.85e-053167211564973
Pubmed

PDGFRβ-positive cell-mediated post-stroke remodeling of fibronectin and laminin α2 for tissue repair and functional recovery.

FN1 LAMA2

6.85e-053167236514952
Pubmed

Thrombomodulin-dependent effect of factor VLeiden mutation on factor XIII activation.

F5 F8

6.85e-053167221774968
Pubmed

Centrosome/spindle pole-associated protein regulates cytokinesis via promoting the recruitment of MyoGEF to the central spindle.

PLEKHG6 CSPP1

6.85e-053167219129481
Pubmed

Quantitative proteomics revealed novel proteins associated with molecular subtypes of breast cancer.

A2M FN1

6.85e-053167227498393
Pubmed

Quantitative proteomics identify Tenascin-C as a promoter of lung cancer progression and contributor to a signature prognostic of patient survival.

FN1 TNC

6.85e-053167228652369
Pubmed

Value of gene polymorphisms as markers of 5-FU therapy response in stage III colon carcinoma: a pilot study.

DPYD UMPS

6.85e-053167220665215
Pubmed

Loss of FLCN-FNIP1/2 induces a non-canonical interferon response in human renal tubular epithelial cells.

FNIP2 FNIP1

6.85e-053167233459596
Pubmed

Delayed re-epithelialization in periostin-deficient mice during cutaneous wound healing.

FN1 POSTN

6.85e-053167221490918
Pubmed

Expression of thymidylate synthase, dihydropyrimidine dehydrogenase, thymidine phosphorylase, and orotate phosphoribosyl transferase in prostate cancer.

DPYD UMPS

6.85e-053167215999119
Pubmed

A Rac/Cdc42 exchange factor complex promotes formation of lateral filopodia and blood vessel lumen morphogenesis.

DOCK4 CSPG4

6.85e-053167226129894
Pubmed

Thymidylate synthase, dihydropyrimidine dehydrogenase, orotate phosphoribosyltransferase mRNA and protein expression levels in solid tumors in large scale population analysis.

DPYD UMPS

6.85e-053167219020767
Pubmed

TGF beta in murine morphogenetic processes: the early embryo and cardiogenesis.

FN1 TNR

6.85e-05316721696875
InteractionSLC6A4 interactions

A2M FN1 ARHGAP23 MYO9A TNC VPS13C SORBS1 ADGRV1 GRIP1 SBF1 TRIM32 PAM PNPLA8 TNR VDAC3

3.01e-0643716415int:SLC6A4
Cytoband15q24.2

ADAMTS7 CSPG4 UBE2Q2

2.17e-0432167315q24.2
Cytoband7p14.3

TRIL INMT TBX20

3.63e-043816737p14.3
GeneFamilySolute carriers

SLCO4A1 SLC34A2 SLC7A6 SLCO1B7 SLC6A3 SLC12A1 SLC12A3 SLC12A9 SLC35D3 SLC9A7 SLC26A6

3.43e-0539511211752
GeneFamilyGuanylate cyclase receptors|DENN/MADD domain containing

FNIP2 SBF1 FNIP1

4.82e-04251123504
GeneFamilyImmunoglobulin like domain containing

BOC LAG3 PTPRT SEMA4C HMCN2 MDGA1

1.28e-031931126594
GeneFamilyC3 and PZP like, alpha-2-macroglobulin domain containing

A2M C5

1.33e-03911221234
GeneFamilyPatatin like phospholipase domain containing

PNPLA2 PNPLA8

1.66e-03101122466
GeneFamilyPleckstrin homology domain containing|SH2 domain containing|C2 and RasGAP domain containing

SYNGAP1 RASAL1

1.66e-03101122830
GeneFamilyKelch like|BTB domain containing

KLHL1 GAN KLHL8

2.23e-03421123617
GeneFamilyPDZ domain containing

ARHGAP23 TIAM2 GRIP1 GRIP2 LNX1

2.56e-0315211251220
GeneFamilyFibronectin type III domain containing

BOC FN1 TNC PTPRT TNR

3.20e-031601125555
GeneFamilyCadherin related

FAT3 DCHS1

4.87e-0317112224
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS19 ADAMTS7

6.07e-0319112250
CoexpressionMILI_PSEUDOPODIA_CHEMOTAXIS_DN

ABCC1 PNKP FN1 MFSD9 APLP2 TM2D3 SLC7A6 SEMA4C SLC12A9 P3H1 DHRS7 CSPG4 KCNN4 PAM GAA

2.60e-0745716715M1613
CoexpressionMILI_PSEUDOPODIA_CHEMOTAXIS_DN

ABCC1 PNKP FN1 MFSD9 APLP2 TM2D3 SLC7A6 SEMA4C SLC12A9 P3H1 DHRS7 CSPG4 KCNN4 PAM GAA

3.72e-0747016715MM1053
CoexpressionGSE11924_TH1_VS_TH2_CD4_TCELL_UP

FNIP2 BOC PNMT ASPG OXA1L AARS2 GAN EXOC7 DCLK1 RASAL1

6.68e-0720016710M3159
CoexpressionLAKE_ADULT_KIDNEY_C28_INTERSTITIUM

A2M DPYD TNC LAMA2 SORBS1 REV3L

1.89e-05861676M39247
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HDA

DOCK4 KLHL1 ARHGAP23 FAT3 MUC16 TM2D3 GRIP1 PDE4DIP TSPAN13 ACTL6B GRIP2 UBE2QL1 DCLK1

2.33e-0550616713M39067
CoexpressionLEE_BMP2_TARGETS_UP

DPYD DSP ASPG LAMA2 REV3L F5 TRIL DHRS7 KCNK1 CYB5R3 DCHS1 PAM BACE2 GAA PADI1 TLCD5

4.16e-0578016716M2324
CoexpressionGSE5589_IL6_KO_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_UP

ABCC1 DPYD FN1 ASPG POSTN TSPAN13 NNMT RASAL1

4.49e-052001678M6655
CoexpressionAtlasdev gonad_e13.5_F_SupCellPrec_Sry_top-relative-expression-ranked_1000

ARHGAP42 BOC DOCK4 ADAMTS19 ZMPSTE24 MYO9A PPFIBP2 VPS13C REV3L GK5 SYNGAP1 DHRS7 SLC9A7 PAM CERCAM ADGRE5 KLHL8 BACE2 DCLK1 VDAC3

3.78e-0680416320gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_1000

ARHGAP42 BOC DOCK4 ADAMTS19 LCORL MYO9A FAT3 MUC16 REV3L GK5 SYNGAP1 POSTN TRIL DHRS7 SLC9A7 PAM ADGRE5 BACE2 DCLK1

4.29e-0674016319gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_1000
CoexpressionAtlasdev gonad_e12.5_F_SupCellPrec_Sry_top-relative-expression-ranked_1000

ARHGAP42 BOC DOCK4 ADAMTS19 MYO9A PPFIBP2 REV3L GK5 SYNGAP1 DHRS7 SLC9A7 PAM CERCAM ADGRE5 KLHL8 BACE2 CSPP1 DCLK1 VDAC3

1.36e-0580316319gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_1000
CoexpressionAtlasdev gonad_e11.5_F_SupCellPrec_Sry_top-relative-expression-ranked_1000

DOCK4 ABCC1 DSP MYO9A MUC16 REV3L GK5 F8 SYNGAP1 P3H1 DHRS7 SLC9A7 CERCAM ADGRE5 KLHL8 CSPP1 DCLK1 VDAC3

3.88e-0579116318gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_1000
CoexpressionAtlasdev gonad_e12.5_F_SupCellPrec_Sry_top-relative-expression-ranked_500

DOCK4 ADAMTS19 MYO9A REV3L GK5 SYNGAP1 DHRS7 PAM ADGRE5 KLHL8 BACE2 DCLK1

8.85e-0541416312gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_500
CoexpressionAtlasdev gonad_e13.5_F_SupCellPrec_Sry_top-relative-expression-ranked_500

ARHGAP42 BOC DOCK4 ADAMTS19 MYO9A GK5 DHRS7 SLC9A7 ADGRE5 KLHL8 BACE2 DCLK1

1.06e-0442216312gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_500
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#4_top-relative-expression-ranked_1000

DOCK4 ADAMTS19 MYO9A REV3L GK5 SYNGAP1 DHRS7 PAM BACE2 DCLK1

1.15e-0430116310gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k4_1000
ToppCellCOVID-19-Heart-CM_4|Heart / Disease (COVID-19 only), tissue and cell type

FNIP2 F5 GRIP1 GRHL1 RHBDL2 MROH1 KCNK1 KLHL8 UBE2QL1 TBX20

2.83e-09190167103729648a17093b438398b82e32bbccc3af7b8c5d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A2M FN1 TNC FAT3 LAMA2 SORBS1 PTGIS POSTN CSPG4 DCLK1

2.83e-091901671070c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCell21-Trachea-Mesenchymal-Mesenchyme_RSPO2+|Trachea / Age, Tissue, Lineage and Cell class

A2M FN1 KIF26A TNC FAT3 LAMA2 POSTN INMT CSPG4

5.32e-0819416798fc98d2c9d94f3bc6292265e20ab71c4f1f37bb3
ToppCellPCW_10-12-Epithelial-Epithelial_proliferating|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DSP RASSF10 SLC34A2 ADGRV1 GRIP1 FGF20 KCNK1 TSPAN13 MAP3K21

5.56e-081951679ce1ba5911e8a6ddb07434acc37147c38e94245ff
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

BOC FN1 LAMA2 PTGIS POSTN P3H1 CERCAM NNMT DCLK1

5.81e-081961679525d6c8a277364e624e7cc586275f8a891436b57
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DSP RASSF10 SLC34A2 ADGRV1 GRIP1 FGF20 KCNK1 TSPAN13 MAP3K21

6.07e-08197167922b26bac3a99b20c73bfa6e6f81026d064eaa9e8
ToppCellPCW_13-14-Epithelial|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DSP RASSF10 SLC34A2 ADGRV1 GRIP1 FGF20 KCNK1 TSPAN13 MAP3K21

6.34e-08198167948eb6f69a464a34ab32e8d425a22b9d45ec20428
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-early_osteoblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

A2M FN1 TNC FAT3 PTGIS RHBDL2 P3H1 CERCAM NNMT

6.34e-0819816796a539d3b47bd2d4a7ad5c67cad23facffc0ac45f
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma-early_osteoblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

A2M FN1 TNC FAT3 PTGIS RHBDL2 CSPG4 CERCAM NNMT

6.91e-08200167916a7c398626b6e82b394eb3ef013bda3a788659d
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

A2M FN1 TNC FAT3 PTGIS RHBDL2 CSPG4 CERCAM NNMT

6.91e-082001679780d47f8eff630020dfae32218de495a7e9dbad6
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

A2M FN1 TNC FAT3 PTGIS RHBDL2 CSPG4 CERCAM NNMT

6.91e-08200167928dd127787a57276253548d1f030814b1af64481
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DPYD FN1 ASPG FAT3 ADGRV1 ADAMTS7 INMT CSPG4

2.68e-071701678ba4ba66b624089ed50a9083176386c7941b4c7a3
ToppCellfacs-Trachea-nan-24m-Mesenchymal-chondrocyte|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FN1 ASPG IL20RA TIAM2 TSPAN13 TAS1R2 PAM MDGA1

3.06e-0717316782226505610af1becc253d0a5550627144ef0ed6b
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 A2M FN1 ARHGAP23 ASPG POSTN CSPG4 ABHD1

3.34e-07175167812f5fd83c7710fc0c77406f765d9cbd133433b8b
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FN1 TNC FAT3 PTGIS RHBDL2 CERCAM UBE2QL1 NNMT

3.80e-071781678e32f5ed7a492edfa7073416008b1fcfae6b854ad
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

A2M FN1 TNC FAT3 SORBS1 HMCN2 CLMN ADGRE5

4.69e-071831678818fd886e0188091310825f9145fa53328f2c979
ToppCellCOVID-19-Epithelial_cells-ECM-high_epithelial|COVID-19 / group, cell type (main and fine annotations)

A2M FN1 DSP LAMA2 SLC34A2 SORBS1 ADGRV1 TSPAN13

4.69e-071831678dc1d380bf7564f290256cb7108063d1bd2da732b
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 GK5 FER1L6 RHBDL2 TSPAN13 GAN BACE2 PADI1

6.48e-071911678cd709bbcd320373468ea7f058ee5fda8a067b5d0
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FN1 TNC FAT3 LAMA2 SORBS1 PTGIS POSTN DCLK1

6.48e-071911678107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 GK5 FER1L6 RHBDL2 TSPAN13 GAN BACE2 PADI1

6.48e-071911678e14b22e882ac92acf8c8b6ee997ef8e799c7a8d5
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 GK5 FER1L6 RHBDL2 TSPAN13 GAN BACE2 PADI1

6.48e-07191167814851529025cfc2b665f71ebad04150ec543da7a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FN1 TNC FAT3 LAMA2 SORBS1 PTGIS POSTN DCLK1

6.48e-071911678bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

BOC ADAMTS19 LAMA2 PTGIS HMCN2 CERCAM GRIP2 DCLK1

6.74e-0719216788d56e360ebc624ca4cd7f0af4f3cc599c244f134
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Mesenchymal-mesenchymal_stem_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FN1 LAMA2 PTGIS INMT PAM CERCAM NNMT DCLK1

7.01e-071931678160691b671710be10220803d788c2c961c236af1
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP23 PPFIBP2 IL20RA GRIP1 RHBDL2 PLEKHG6 KCNN4 ADGRE5

7.01e-071931678a5695ce2e24a62026ae28f3dea07ca4a435206b8
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A2M FN1 TNC LAMA2 PTGIS POSTN INMT NNMT

7.29e-071941678d3db241ea316bbcde6d16618193b474591ad5ce4
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DSP RASSF10 SLC34A2 ADGRV1 FGF20 KCNK1 TSPAN13 MAP3K21

7.29e-071941678c47fc3f716ab091a39c20d7639ac783029589ee5
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A2M FN1 TNC LAMA2 PTGIS POSTN INMT NNMT

7.29e-07194167829f83cdd63314fff41258937d70b881a5503bfcc
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 A2M TNC LAMA2 SORBS1 REV3L ADGRE5 DCLK1

7.58e-071951678803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 A2M TNC LAMA2 SORBS1 REV3L ADGRE5 DCLK1

7.58e-0719516784f70157d42a16ff0259bc24a62803c4df4285c44
ToppCell10x5'v1-week_14-16-Mesenchymal_myocytic-stroma-myofibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

A2M FN1 TNC PPFIBP2 FAT3 RHBDL2 CSPG4 NNMT

7.58e-07195167830ed961151b8b1f6ce37f06c9a061519f01c2864
ToppCellwk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_late|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

DSP ASPG RASSF10 SLC34A2 FGF20 TSPAN13 C5 MAP3K21

7.88e-07196167875e9e430a4f55ef10f2e3132afa690fc8bfaff83
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 A2M TNC LAMA2 SORBS1 REV3L ADGRE5 DCLK1

7.88e-0719616782b36b9a40fe415917afccff99ad9c3474e087d0d
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DSP RASSF10 SLC34A2 ADGRV1 GRIP1 FGF20 TSPAN13 MAP3K21

7.88e-0719616780a34a0009f479384f1994c6f977f942699a132c8
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DSP RASSF10 SLC34A2 ADGRV1 GRIP1 KCNK1 TSPAN13 MAP3K21

7.88e-0719616787b17d47b7758d8ccf9dbefd097aeb553791a1eed
ToppCellwk_15-18-Epithelial-Distal_epithelial_progenitor|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

DSP ASPG RASSF10 SLC34A2 FGF20 TSPAN13 C5 MAP3K21

7.88e-07196167800bef0e47739932fd1da109cd607de0789d14ca5
ToppCellRA-02._Fibroblast_II|World / Chamber and Cluster_Paper

ABCC1 FN1 LAMA2 REV3L PTGIS TBX20 NNMT DCLK1

7.88e-071961678e8cbda03837f1f26470a9d93aa7fdaa04e08e38a
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

A2M FN1 TNC FAT3 PTGIS RHBDL2 CERCAM NNMT

8.18e-0719716782ca5ebb708935a90b12b8e98a22ae2d664ed002e
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CACNA1F DSP VPS13C SLC34A2 ADGRV1 SLC12A9 C5 DCLK1

8.18e-071971678b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteoblast_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

A2M FN1 TNC PPFIBP2 FAT3 PTGIS RHBDL2 NNMT

8.50e-0719816789d61483b0decac2fe90045b3474843360b2c49b3
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

A2M FN1 TNC FAT3 PTGIS RHBDL2 CERCAM NNMT

8.83e-0719916787b1b3b108d817fb3b50a710c3146b30bcf9c2f6b
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro-stroma-arteriolar_fibroblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

BOC ADAMTS19 FN1 LAMA2 POSTN TRIL CSPG4 DCLK1

8.83e-07199167895d95e9b7bd3933188998ae94986213eb0f1e5ea
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DSP MUC16 GK5 FER1L6 GSR TSPAN13 GAN BACE2

8.83e-0719916780c060ef64341659f4b1247d0264ac12e53a7e12e
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

A2M FN1 TNC FAT3 PTGIS RHBDL2 CERCAM NNMT

8.83e-071991678bf138cc692df727e087d140c014149ee5da00d9d
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

A2M FN1 TNC FAT3 PTGIS RHBDL2 CERCAM NNMT

8.83e-071991678d65ee89d5c7e8ed693d58e6a6de09565840e11c5
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DSP MUC16 GK5 FER1L6 GSR TSPAN13 GAN BACE2

8.83e-0719916788bf8d7cd774479f065bbbbcb5a4bd1aa91aa0d85
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

A2M FN1 TNC FAT3 PTGIS RHBDL2 CERCAM NNMT

8.83e-071991678f2ad641f36c577ff7019e88ad6b73ed7e46d8c74
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FNIP2 DSP PPFIBP2 GRIP1 GRHL1 KCNN4 LNX1 RASAL1

9.17e-072001678030efc36bbb848da31b0db3f74d46aac9c79cc9b
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-4-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FN1 TNC LAMA2 PTGIS POSTN P3H1 CERCAM NNMT

9.17e-0720016784dbe21cb63569f28c7017cda065ea5ee00d7254e
ToppCellTracheal-NucSeq-Stromal-Chondrocytic-Chondrocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

A2M BOC FN1 SORBS1 CSPG4 PDE4DIP CERCAM NNMT

9.17e-072001678f5bd0b30e478dac09f68c46b0781f5f2e7e3c693
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-4|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

FN1 TNC LAMA2 PTGIS POSTN P3H1 CERCAM NNMT

9.17e-0720016788256511b099c3eab8e33194f90c9ff354e7cfe8e
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 ADGRV1 GRIP1 TSPAN13 KCNN4 BACE2 LNX1 RASAL1

9.17e-0720016780eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCell5'-Airway_Nasal-Epithelial|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DSP MUC16 GK5 FER1L6 GSR RHBDL2 GAN BACE2

9.17e-072001678358d71329921451c7f5a56f1db0f9989af2299dc
ToppCellTracheal-NucSeq-Stromal-Chondrocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

A2M BOC FN1 SORBS1 CSPG4 PDE4DIP CERCAM NNMT

9.17e-072001678b5a54b9baf79aea01f76a161f0a39bbe87eb4945
ToppCell5'-Airway_Nasal|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DSP MUC16 GK5 FER1L6 GSR RHBDL2 GAN BACE2

9.17e-072001678f6e967738b4f7b173d6e9977e305f77380dd6c8a
ToppCellParenchyma_COVID-19-Stromal-TX-Fibroblasts-4|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

FN1 TNC LAMA2 PTGIS POSTN P3H1 CERCAM NNMT

9.17e-072001678bde938e5a18844fb8cc1d1be5a086809f7e2b97d
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

BOC FN1 TNC FAT3 PTGIS RHBDL2 CERCAM NNMT

9.17e-0720016783c898e81444b001835c3f1bbc68183078701b135
ToppCell356C-Fibroblasts|356C / Donor, Lineage, Cell class and subclass (all cells)

BOC FN1 LAMA2 PTGIS INMT CERCAM NNMT DCLK1

9.17e-0720016789c95329f0b26ff378de803030d4c28517b3adc85
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DSP MUC16 GK5 FER1L6 GSR RHBDL2 GAN BACE2

9.17e-072001678b68d212159b9d04866ba02ff55c35be247805eec
ToppCelltumor_Lung-Fibroblasts|tumor_Lung / Location, Cell class and cell subclass

A2M BOC FN1 LAMA2 PTGIS INMT CERCAM NNMT

9.17e-072001678073a68b5ce232203ffee86342cba2a00d907e119
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

BOC FN1 TNC FAT3 PTGIS RHBDL2 CERCAM NNMT

9.17e-0720016783eca8ffeb41b664fbdbbd70b375c5d953503ab29
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS19 FAT3 LAMA2 ADGRV1 PTPRT GRIP1 SLC12A1

2.48e-061601677c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS19 FAT3 LAMA2 ADGRV1 PTPRT GRIP1 SLC12A1

2.48e-06160167725c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell367C-Fibroblasts-Fibroblast-G-|367C / Donor, Lineage, Cell class and subclass (all cells)

ARHGAP42 A2M DOCK4 FN1 INMT MDGA1 NNMT

3.42e-061681677b8c65542a0701ae31f49d332d87a64578e24b4e3
ToppCell367C-Fibroblasts-Fibroblast-G|367C / Donor, Lineage, Cell class and subclass (all cells)

ARHGAP42 A2M DOCK4 FN1 INMT MDGA1 NNMT

3.42e-0616816778c95093b1ea45826f62893edd3c410fe53b563a4
ToppCellNS-critical-d_0-4-Epithelial-Secretory|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

BOC SLC34A2 RHBDL2 KCNK1 TSPAN13 GGACT BACE2

3.56e-061691677aec97583b23112060437b619cb429dc32f29285f
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VPS13C F8 PTPRT SLC35D3 PDE4DIP SLC9A7 BACE2

4.31e-061741677f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DSP MUC16 ADGRV1 GK5 FER1L6 GRHL1 PADI1

5.20e-0617916776e965e424eebef50f0202cff75f458be395cfca1
ToppCellAdult-Epithelial-lung_goblet_cell|Adult / Lineage, Cell type, age group and donor

DSP IL20RA MUC16 FER1L6 GRHL1 BACE2 LNX1

5.20e-0617916771fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCell(2)_5-FU-(4)_COL2.3+_osteoblasts|(2)_5-FU / Stress and Cell class

BOC FN1 PPFIBP2 POSTN RHBDL2 P3H1 PDE4DIP

5.59e-06181167756ae86072858c156681507aecd1bc6cb0a3372d2
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BOC FN1 TNC LAMA2 GPR88 PTGIS PAM

5.80e-0618216773dfa9187e9d2bab1d199079d29209c4648220ada
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

FN1 TNC LAMA2 PTGIS F8 TBX20 DCLK1

5.80e-061821677fbd5e332df73bf7141c822fa67b76367dc962017
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 PTGIS ADAMTS7 INMT CERCAM BACE2 NNMT

6.01e-06183167763294d66e3ccf152ffe5d1237106764c14390b62
ToppCellCOVID-19-Heart-CM_4|COVID-19 / Disease (COVID-19 only), tissue and cell type

SYNM PCDHGA1 F5 RHBDL2 KCNK1 UBE2QL1 TBX20

6.01e-0618316772902b6e8aa9a6f62bc1a792c971ab7f651a8e676
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 PTGIS ADAMTS7 INMT CERCAM BACE2 NNMT

6.01e-0618316777e5c467fd1b156b928f1611a12ab4affb9f714b7
ToppCellRA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

A2M FN1 TNC FAT3 SORBS1 HMCN2 ADGRE5

6.01e-061831677cae2ee08f985a6f005b4b8e959e465350315156a
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2-Slc17a8.Synpr-Sncg-Yjefn3_(Neuron.Gad1Gad2-Slc17a8.Synpr-Sncg-Yjefn3)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TNC SLC34A2 EFHC1 ADAMTS7 CERCAM

6.15e-066916750862e6c8d8af4310b9a1f0879e51ee25115b26b1
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2-Slc17a8.Synpr-Sncg-Yjefn3_(Neuron.Gad1Gad2-Slc17a8.Synpr-Sncg-Yjefn3)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TNC SLC34A2 EFHC1 ADAMTS7 CERCAM

6.15e-06691675d2ff9cea216122d697822cdd2eecbce8f557728d
ToppCellControl-Epithelial-Club|Epithelial / Disease state, Lineage and Cell class

ARHGAP42 ABCC1 ARHGAP23 GRIP1 GRHL1 GAN DCLK1

6.45e-0618516776814b3c94c7558443c038a227b5c8563d2cfeac4
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

FN1 TNC LAMA2 PTGIS HMCN2 TBX20 DCLK1

6.45e-0618516778f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCellmoderate-Lymphoid-NK|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FN1 TNC ABCB5 POSTN CSPG4 DCHS1 NNMT

6.45e-0618516774979a787acbc9b4ca8defe91cc79b674e51af1bf
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

ADAMTS19 FN1 LAMA2 PTGIS HMCN2 NNMT DCLK1

6.92e-0618716774ea486991f66c29728d127171a07b81404ec0b78
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M TNC ASPG LAMA2 POSTN INMT CSPG4

6.92e-061871677ac8e092b37e042975e2ee057d3f7c6821e58e8b5
ToppCellEndothelial-A-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

A2M PNMT SLCO4A1 GPR88 PTGIS F8 POSTN

6.92e-061871677fd93f3f4b82dae3bf4eef245bfedc2a9e3251b61
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M TNC ASPG LAMA2 POSTN INMT CSPG4

6.92e-061871677d591a3c216997663ab77710fed0d230ffc37e41a
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M TNC ASPG LAMA2 POSTN INMT CSPG4

6.92e-061871677d1dc8c9a2c2cd10c640257161a75e7730ec5bb41
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

A2M FN1 TNC FAT3 SORBS1 HMCN2 ADGRE5

7.17e-06188167734e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BOC SLC34A2 ADGRV1 GK5 C5 MAP3K21 LNX1

7.17e-0618816774bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

A2M FN1 TNC FAT3 SORBS1 HMCN2 ADGRE5

7.42e-0618916776b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 GK5 FER1L6 GRHL1 KCNK1 TSPAN13 GAN

7.68e-0619016776ea9fa08bd97bedcb21d3654467e7f8dd74c8fd0
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FN1 PTGIS POSTN CSPG4 GRIP2 TBX20 DCLK1

7.95e-0619116779431ffd6b758f756609d9057de2023596e22b5d4
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BOC TNC LAMA2 PTGIS POSTN PAM TBX20

7.95e-0619116774b50fdd310701251e64e16cd2d07ce03dbfd3e3e
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BOC TNC LAMA2 PTGIS POSTN PAM TBX20

7.95e-06191167775d2197076a9dfc868e8baf95bd4c5e44f438e3e
ToppCellPCW_13-14-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DSP ADGRV1 GRIP1 KCNK1 MAP3K21 LNX1 RASAL1

7.95e-06191167763aa671837b79d2feb7ed1e67712cc01caf72bef
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

A2M FN1 LAMA2 SORBS1 CLMN CSPG4 GRIP2

7.95e-06191167704c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-osteoblast_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FN1 TNC PPFIBP2 FAT3 PTGIS RHBDL2 CERCAM

7.95e-06191167798b907f8fa024cf32e462323b782c5a371327bbd
ToppCellmetastatic_Lymph_Node-Fibroblasts-Myofibroblasts|Fibroblasts / Location, Cell class and cell subclass

FN1 PSMB7 POSTN PAM NNMT

8.13e-06731675116259a036373bccaeb77fe3c675741a5ca81c52
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating1_(8)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DSP RASSF10 SLC34A2 ADGRV1 FGF20 TSPAN13 MAP3K21

8.22e-0619216778898332387e5d746feb346ce1dabd6b2218fc6e5
ToppCellCOPD-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

A2M DOCK4 FN1 TNC FAT3 POSTN INMT

8.22e-06192167762904f94dfce430456f05066522cbf9bd29f4d7e
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M FN1 TNC LAMA2 POSTN HMCN2 NNMT

8.50e-061931677dc8e62df6121ee99b156aca6b1b3ae555739b6f2
Drugbumetanide

DPYD PSMB10 SLC34A2 GSR SLC6A3 SLC12A1 SLC12A3 ACTL8 SLC12A9 SLC9A7 KCNN4 ACTL6B

4.31e-0820916512CID000002471
Drugtetrahydroisoquinoline

BOC PNMT SLC6A3 TRIM32 INMT NNMT

3.18e-06561656CID000007046
Drugdiphenyl disulfide

DPYD CNOT6 UMPS C5

7.52e-06181654CID000013436
DrugFlavin-Adenine Dinucleotide

DPYD GSR AIFM1 CYB5R3

7.52e-06181654DB03147
Drug0ZI

A2M BOC F5 F8

1.18e-05201654CID000122235
Diseaseunipolar depression, multiple sclerosis

RASSF10 TM2D3 PADI1

3.32e-05121603EFO_0003761, MONDO_0005301
Diseaseglutarylcarnitine (C5-DC) measurement

FNIP2 ABCC1 SLC7A6

1.01e-04171603EFO_0800030
Diseaseasparagine measurement, amino acid measurement

KIF26A ASPG

1.74e-0441602EFO_0005134, EFO_0009766
Diseaseguanylyl cyclase-activating protein 1 measurement

PGLYRP2 F5

1.74e-0441602EFO_0801663
DiseaseCis-4-decenoyl carnitine measurement

FNIP2 ABCC1

2.89e-0451602EFO_0022091
Diseaselimb-girdle muscular dystrophy (implicated_via_orthology)

FER1L6 GSR

6.03e-0471602DOID:11724 (implicated_via_orthology)
Diseaseserum metabolite measurement

ABCC1 DPYD KLHL1 ASPG TM2D3 REV3L SLC7A6 PTPRT MROH1 CLMN CYB5R3 UMPS MDGA1 LNX1

6.63e-0494516014EFO_0005653
Diseasecerebellar ataxia (implicated_via_orthology)

VPS13C AARS2

8.01e-0481602DOID:0050753 (implicated_via_orthology)
DiseaseColorectal Neoplasms

BOC ABCC1 DPYD ABCB5 POSTN UMPS DCLK1

8.20e-042771607C0009404
Diseaseoctanoylcarnitine measurement

FNIP2 ABCC1

1.03e-0391602EFO_0021042
Diseasemacrovascular complications of diabetes

F5 PDE4DIP

1.28e-03101602EFO_0010977
DiseaseCharcot-Marie-Tooth disease

MPZ SBF1 AIFM1

1.54e-03421603cv:C0007959
DiseaseEnzymopathy

GSR PKLR

1.56e-03111602C0520572
DiseaseColorectal Carcinoma

BOC ABCC1 DPYD FN1 ABCB5 F5 PTPRT POSTN DCHS1 UMPS DCLK1

1.62e-0370216011C0009402
Diseaseglutaroyl carnitine measurement

ABCC1 SLC7A6

2.19e-03131602EFO_0021005
Diseasevascular brain injury measurement, vascular brain injury

RASSF10 TRIL

2.19e-03131602EFO_0006791, EFO_0006800
DiseaseCharcot-Marie-Tooth disease type 4

MPZ SBF1

2.19e-03131602cv:C4082197
DiseaseBardet-Biedl syndrome (is_implicated_in)

MKS1 TRIM32

2.55e-03141602DOID:1935 (is_implicated_in)
DiseaseMeckel-Gruber syndrome

MKS1 CSPP1

2.93e-03151602C0265215
Diseasehigh grade glioma (biomarker_via_orthology)

TNC SLC6A3

2.93e-03151602DOID:3070 (biomarker_via_orthology)
DiseaseEarly Pregnancy Loss

FN1 IL20RA PTGIS TNR

2.98e-031091604C3830362
DiseaseSpontaneous abortion

FN1 IL20RA PTGIS TNR

2.98e-031091604C0000786
DiseaseMiscarriage

FN1 IL20RA PTGIS TNR

2.98e-031091604C4552766
DiseaseAbortion, Tubal

FN1 IL20RA PTGIS TNR

2.98e-031091604C0000822
DiseasePeripheral Nervous System Diseases

ABCC1 DPYD GAN

3.17e-03541603C4721453
Diseasemetabolite measurement

ABCC1 ASPG REV3L SLC7A6 ADH6 RNPEP ABHD1 TBX20 MDGA1

3.61e-035601609EFO_0004725
Diseasevenous thromboembolism

ABCC1 F5 F8 PTPRT CNOT6 CLMN CYB5R3 MAP3K21

3.74e-034601608EFO_0004286
DiseaseBardet-Biedl syndrome 1 (disorder)

MKS1 TRIM32

3.77e-03171602C2936862
Diseasemuscular dystrophy (is_implicated_in)

LAMA2 TRIM32

3.77e-03171602DOID:9884 (is_implicated_in)
DiseasePolydactyly

MKS1 GRIP1 TRIM32 CSPP1

3.84e-031171604C0152427
Diseaseblood nickel measurement

ABCC1 MUC16 F5 SLC12A1

4.20e-031201604EFO_0007583
DiseaseMeckel syndrome type 1

MKS1 CSPP1

4.22e-03181602C3714506
Diseaseessential hypertension (is_implicated_in)

PTGIS SLC12A3

4.22e-03181602DOID:10825 (is_implicated_in)
DiseaseBardet-Biedl syndrome

MKS1 TRIM32

4.22e-03181602cv:C0752166
Diseasediet measurement, HOMA-B

KLHL1 FAT3

4.70e-03191602EFO_0004469, EFO_0008111
Diseaseacylcarnitine measurement

ABCC1 PTPRT SLCO1B7 USP6NL

5.13e-031271604EFO_0005059

Protein segments in the cluster

PeptideGeneStartEntry
SLIGLGYTQTLRPGV

VDAC3

241

Q9Y277
SGGGVLEERPLTLYR

ATAD5

1406

Q96QE3
YVLLVVGGGPTLDSL

CATSPERG

946

Q6ZRH7
GGSLVLGGIEPSLYK

BACE2

246

Q9Y5Z0
SLPLISIVGYVDGGI

BTNL3

136

Q6UXE8
PTLSYIGGGILSQDR

ARSH

386

Q5FYA8
LQVLLTYRVGEGPGV

RNPEP

136

Q9H4A4
GVLSYLEPRGSLLLG

CSPG4

311

Q6UVK1
LGPDVGYEAIGLVDS

AIFM1

486

O95831
LLYPTILGHEGAGIV

ADH6

61

P28332
GLLTGVVVDSGYGLT

ACTL8

141

Q9H568
SLILNGEPGYTIGTV

ABCB5

311

Q2M3G0
DIRPGLYGSVIVTGG

ACTL6B

336

O94805
PGRSVIVGAGYIAVE

GSR

231

P00390
GVPLLIVGVSAAIYS

ADGRE5

661

P48960
SLVRGPGILGEVTVF

ADGRV1

4176

Q8WXG9
GVYLLPGQVSGVALD

PAM

506

P19021
TYGGVSGTAIRPIAL

DPYD

761

Q12882
GAEREYGGIIPISLP

C7orf31

61

Q8N865
GLRTELATYPGIIVS

DHRS7

216

Q9Y394
GVTLRPDVYGEKGLE

ATP4B

81

P51164
IYLRSSSGEGIGVIG

CFAP44

176

Q96MT7
EAEGLGYVDVGLIPA

ADAMTS7

706

Q9UKP4
GYVDVGLIPAGAREI

ADAMTS7

711

Q9UKP4
LIYAVLPTGDVIGDS

A2M

541

P01023
LRGYGPGIRVDEVSF

AP4M1

241

O00189
TYLVGAGIELDGSRP

RASSF10

276

A6NK89
SLGLLTGYLGPIVDA

RASAL1

411

O95294
TGYLGPIVDAIVGSV

RASAL1

416

O95294
PEDKTITTLYVGGLG

RBM22

226

Q9NW64
IGDTIEFRGPSGLLV

CYB5R3

136

P00387
GGTEYPLGRILIGSS

PADI1

421

Q9ULC6
GGLPYELTEGDIICV

RBMX2

41

Q9Y388
GAGYVEVLVIPAGAR

ADAMTS19

801

Q8TE59
TREGGPLLYEGISLT

P3H1

446

Q32P28
LVLGGVDVTGPHLYS

PSMB7

141

Q99436
VGLTAPALALAGYIE

APLP2

21

Q06481
RGPGYLGDIAIDDVT

MDGA1

896

Q8NFP4
PLLLVEEGAAGEGYL

CACNA1F

1851

O60840
PIGKGYITEGRLDTS

MUC16

1041

Q8WXI7
GLLLPGAGATLYREE

DCHS1

3096

Q96JQ0
GVRYVDGGISDNLPL

PNPLA2

161

Q96AD5
LYGAGPSDSGTRVLI

CT55

101

Q8WUE5
RIPVSLLYSGLAIGG

GPR88

31

Q9GZN0
SPGLLTYVLEELERG

MAP1S

26

Q66K74
ITFLTIGYGDVVPGT

KCNN4

246

O15554
ILGPVVGGYLTELED

MFSD9

181

Q8NBP5
VRVPLYTLRDGVGGL

NUDT16

141

Q96DE0
YTLRDGVGGLPTFLE

NUDT16

146

Q96DE0
GDTLIDIGSGPTIYQ

INMT

56

O95050
GPERRLLAVYTGGTI

ASPG

6

Q86U10
PQLYVSGELIGGLDI

GLRX3

201

O76003
LLRVSGVSYSGVAPG

HMCN2

411

Q8NDA2
LEISGIIPTDGGRYQ

HMCN2

571

Q8NDA2
RLDVYVPPTIEGAGG

HMCN2

1616

Q8NDA2
ISLSTIGLGDYVPGE

KCNK1

221

O00180
VGFESILEGLYGPRL

LCORL

51

Q8N3X6
LGDFGLATIVDGPLY

DCLK1

531

O15075
YVAALTTPRGGVGIA

KLHL8

536

Q9P2G9
ALDGVILGDYLSRTP

PGLYRP2

276

Q96PD5
GDLLIDIGSGPTIYQ

NNMT

56

P40261
SLGIDYGLSLPLGED

CSPP1

101

Q1MSJ5
YVISVEPGGVISRDG

LNX1

536

Q8TBB1
VPVGGRIYIDDGLIS

PKLR

211

P30613
IYVGPGGAALSDREL

KIF26A

791

Q9ULI4
LPGSGRLVEGEVYAV

GGACT

56

Q9BVM4
GSGVGRVEYPDLTID

LAMA2

2211

P24043
GILGPLLYGEVGDTL

F8

466

P00451
TPLTVYAGAGSRVGL

LAG3

266

P18627
PGLGRYLEVLIGVSV

LILRB3

436

O75022
FAELGLGSYTPVGLI

OXA1L

111

Q15070
GRLLVVSSSPYLGDG

MROH1

541

Q8NDA8
RTVLSGGSLYIEIPG

OAZ1

131

P54368
TTIIPAGGAGYKVLA

BPNT2

261

Q9NX62
IREGPTGRLEEYLGS

EXOC7

101

Q9UPT5
GLGEEGLLSRLYEEP

IL20RA

511

Q9UHF4
GGLIILEPRFTGDTL

PPFIBP2

746

Q8ND30
GEDGLILTPLGRYQI

SMPD4

701

Q9NXE4
GVYLQEGPVGSTLSL

SBF1

1711

O95248
YEIRVLLTRPGEGGT

PTPRT

356

O14522
PLQGLVASRIETYGG

PLEKHG6

11

Q3KR16
LLRTYAGGAVIPTGT

FAM157B

226

P0CG42
LEGEGSVLKRGPYGT

GRHL1

496

Q9NZI5
SDLPYLIVGVVLGSI

BOC

851

Q9BWV1
SFRGTVPYGLSLEIG

DOCK4

16

Q8N1I0
RLGPGGLDPVEVYES

CDC37

286

Q16543
GSIVVSGLTPGVEYV

FN1

1136

P02751
IGYRITVVAAGEGIP

FN1

1296

P02751
LGDLYGAIGSPVRLA

FNIP1

506

Q8TF40
AQLGDLYGAIGSPVR

FNIP2

486

Q9P278
GAVPIGASIYVIGDL

GAN

521

Q9H2C0
GVTLDPRGIYGTISR

C5

941

P01031
YLTGGLVDPEVHGRI

DSP

2731

P15924
TSPEGQGIIYIIIDG

FAT3

2211

Q8TDW7
RSTGGILDVYIFLGP

GAA

331

P10253
GYAIVRRPTVGIGGD

EFHC1

36

Q5JVL4
RYPGFVLGLDVGSSV

GK5

16

Q6ZS86
VLLGVRAVPSLGYTE

C19orf54

241

Q5BKX5
TLLSVTGEVEPRGYL

CSTF2T

341

Q9H0L4
ETAVEGLPGLVVAGY

CERCAM

456

Q5T4B2
LKRYGGPLGITISGT

GRIP1

676

Q9Y3R0
RYGGPLGITISGTEE

GRIP2

661

Q9C0E4
ETEGTLILLFGGIPY

ZMPSTE24

86

O75844
LPDSGVVEYLSTGGV

CNOT6

416

Q9ULM6
YLVLGTEEPGTGVRL

FUZ

366

Q9BT04
VYTAGLRGGLTPEET

LIPT2

56

A6NK58
DGGEPVRSGTLRIYI

PCDHGA1

216

Q9Y5H4
GLIVRGYRQPLEGSD

ABCC1

226

P33527
GGVGYLSRGDPVRVL

PHF1

531

O43189
LSRPTEGVQALVGGY

PNPLA8

291

Q9NP80
GLVSIRGVDSGLYLG

FGF20

106

Q9NP95
LTDPGDIRTGTKGYL

FER1L6

186

Q2WGJ9
YPGIAENIGESITIG

UTP20

1281

O75691
LTGDPIGYVTGVLAV

SLC35D3

151

Q5M8T2
GGYSVLIREGLTCPV

TRIM32

606

Q13049
IFDPLRYLVGASGGV

RHBDL2

176

Q9NX52
RELYIPSGESEVAGG

SYNM

1071

O15061
TISGLLGPTLYAEVG

F5

81

P12259
LGGRPEVVLEGSYDG

LMF2

461

Q9BU23
ELLTGEVPYRGIDGL

MAP3K21

336

Q5TCX8
ETRGITILGLYRIGG

ARHGAP42

406

A6NI28
TILVGGRYVTVLLDP

PTGIS

66

Q16647
LLYEGRGPGGSSLLI

TACO1

136

Q9BSH4
PGELLTLIGATGISY

SLC26A6

296

Q9BXS9
YLISRSLGPEFGGSI

SLC12A1

246

Q13621
GSTPYGGVKLEDLIV

ACAT1

166

P24752
PGLEGSLGVGDTLYL

PNKP

81

Q96T60
SLIVGGVDLTGPQLY

PSMB10

136

P40306
GGILVPIYFGALIDT

SLCO1B7

536

G3V0H7
LTLTEPTGLLYVGAR

SEMA4C

56

Q9C0C4
GDVVEFRGPSGLLTY

CYB5R1

141

Q9UHQ9
YDLAGGVGAPQLVEL

AARS2

226

Q5JTZ9
LHGVGATPLYTLGVT

SLCO4A1

236

Q96BD0
PYVALLITARGGHIG

ABHD1

346

Q96SE0
QVLYLSRGGVGTTPA

CLMN

796

Q96JQ2
IGVITIERAYPLTLG

SLC34A2

446

O95436
EFLGGLSPGVLDRLY

GTF2H4

21

Q92759
SGRTLIDIGSGPTVY

PNMT

71

P11086
AGAGVGYALLVIVTP

UQCC3

16

Q6UW78
LSIGLSAYIGFIDGP

TLCD5

46

Q6ZRR5
RVVLPVLSGGYVLGG

UBE2Q2

286

Q8WVN8
GSQVIIIAGPGYDAL

ZNF653

316

Q96CK0
IIAGPGYDALTAEGI

ZNF653

321

Q96CK0
SRIEVLPVDTGAGGY

USP6NL

696

Q92738
VLSPRLENGYVLDGG

UBE2QL1

71

A1L167
PIIGEYAGEVLRFVG

TSPAN13

156

O95857
ISDVLPDGLAYGEGL

TIAM2

921

Q8IVF5
GGSLELEDLSYVRIP

MKS1

451

Q9NXB0
YQTPLLIRSGITGLE

REV3L

2361

O60673
GYVGLVTVPVATLAG

SYNGAP1

341

Q96PV0
EARGLESTGIYRVPG

ARHGAP23

931

Q9P227
TLPGAIDGIRAYLSV

SLC6A3

286

Q01959
YRLLGEEGVALPANG

SLC12A9

11

Q9BXP2
IYKSVLEGGDIPLQG

SORBS1

681

Q9BX66
LVTLPEAGSRGGVDY

TRIL

681

Q7L0X0
TLTGLRPGTEYGIGV

TNC

951

P24821
ATLTDLVPGTEYGVG

TNR

651

Q92752
GLSSPIYIDLRGIVS

UMPS

31

P11172
GGTYFLISRSLGPEL

SLC12A3

201

P55017
ATLEGLYLLVVPGAS

VPS13C

81

Q709C8
PRRVGIALDYEGGTV

TRIM26

486

Q12899
SSLLPGVLLGYEIVD

TAS1R2

86

Q8TE23
SLIGIGIALSGVPFY

SLC7A6

451

Q92536
LLEAGPYSGLGEIIH

ZSWIM6

746

Q9HCJ5
RSPIRTYGGEEDVLG

TBX20

311

Q9UMR3
PTLGGEEGVSRIYAD

GTF3C5

41

Q9Y5Q8
LPIDHVYGTLGIVGA

POSTN

96

Q15063
IVGVILRYGTPATSG

SLC9A7

111

Q96T83
LYLLGAGPVEAGVTQ

TRBV5-3

11

A0A0A0MS03
GLGGLTVYSLGEIIT

TBRG1

186

Q3YBR2
TLIDVLLIGVGYVGP

TM2D3

226

Q9BRN9
LLIGVGYVGPADGSL

TM2D3

231

Q9BRN9
LGVTVLEGPIYAVGG

KLHL1

546

Q9NR64
GVYSGPIGTAILIIA

MYMK

116

A6NI61
PEVGLVNIKGYGSLE

MYO9A

1171

B2RTY4
RGTIELGRILEPGYL

PDE4DIP

1791

Q5VU43
PTRYGVVLGAVIGGV

MPZ

151

P25189