Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	peptidyl-dipeptidase activity	ACE ACE2	3.80e-06	3	23	2	GO:0008241
GeneOntologyMolecularFunction	UDP-galactosyltransferase activity	B3GNT5 ABO	6.16e-04	32	23	2	GO:0035250
GeneOntologyMolecularFunction	galactosyltransferase activity	B3GNT5 ABO	7.38e-04	35	23	2	GO:0008378
GeneOntologyMolecularFunction	carboxypeptidase activity	ACE ACE2	1.44e-03	49	23	2	GO:0004180
GeneOntologyMolecularFunction	metallopeptidase activity	ACE ACE2 ADAM18	1.51e-03	200	23	3	GO:0008237
GeneOntologyMolecularFunction	metalloexopeptidase activity	ACE ACE2	2.92e-03	70	23	2	GO:0008235
GeneOntologyBiologicalProcess	angiotensin maturation	ACE ACE2	4.26e-05	9	23	2	GO:0002003
GeneOntologyBiologicalProcess	regulation of gap junction assembly	ACE ACE2	5.32e-05	10	23	2	GO:1903596
GeneOntologyBiologicalProcess	regulation of angiotensin levels in blood	ACE ACE2	6.50e-05	11	23	2	GO:0002002
GeneOntologyBiologicalProcess	regulation of blood volume by renin-angiotensin	ACE ACE2	1.07e-04	14	23	2	GO:0002016
GeneOntologyBiologicalProcess	gap junction assembly	ACE ACE2	2.01e-04	19	23	2	GO:0016264
GeneOntologyBiologicalProcess	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	ACE ACE2	2.97e-04	23	23	2	GO:0001991
HumanPheno	Abnormal pons morphology	PLK4 FA2H MED23	4.65e-05	117	4	3	HP:0007361
MousePheno	abnormal angiotensin I-converting enzyme activity	ACE ACE2	2.08e-05	6	17	2	MP:0013254
MousePheno	increased angiotensin I-converting enzyme activity	ACE ACE2	2.08e-05	6	17	2	MP:0003184
MousePheno	abnormal circulating angiotensin II level	ACE ACE2	9.12e-05	12	17	2	MP:0031230
MousePheno	abnormal angiotensin II level	ACE ACE2	9.12e-05	12	17	2	MP:0031227
Domain	Peptidase_M2	ACE ACE2	1.32e-06	2	22	2	PF01401
Domain	Peptidase_M2	ACE ACE2	3.97e-06	3	22	2	IPR001548
Domain	ZINC_PROTEASE	ACE ACE2	5.88e-03	98	22	2	PS00142
Pathway	KEGG_MEDICUS_REFERENCE_BLOOD_GROUP_H_O_ANTIGEN_TYPE_1_BIOSYNTHESIS	B3GNT5 ABO	2.57e-05	6	19	2	M47959
Pathway	KEGG_MEDICUS_REFERENCE_BLOOD_GROUP_H_O_ANTIGEN_TYPE_2_BIOSYNTHESIS	B3GNT5 ABO	3.60e-05	7	19	2	M47965
Pathway	WP_SARSCOV2_AND_ACE2_RECEPTOR_MOLECULAR_MECHANISMS	ACE ACE2	3.60e-05	7	19	2	M39867
Pathway	WP_NONCLASSICAL_ROLE_OF_VITAMIN_D	ACE ACE2	4.80e-05	8	19	2	M42566
Pathway	BIOCARTA_ACE2_PATHWAY	ACE ACE2	1.33e-04	13	19	2	MM1347
Pathway	BIOCARTA_ACE2_PATHWAY	ACE ACE2	1.33e-04	13	19	2	M12950
Pathway	REACTOME_METABOLISM_OF_ANGIOTENSINOGEN_TO_ANGIOTENSINS	ACE ACE2	1.79e-04	15	19	2	MM14797
Pathway	WP_ACE_INHIBITOR_PATHWAY	ACE ACE2	2.31e-04	17	19	2	M39680
Pathway	KEGG_RENIN_ANGIOTENSIN_SYSTEM	ACE ACE2	2.31e-04	17	19	2	M17636
Pathway	REACTOME_METABOLISM_OF_ANGIOTENSINOGEN_TO_ANGIOTENSINS	ACE ACE2	2.31e-04	17	19	2	M27104
Pathway	KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_LACTO_AND_NEOLACTO_SERIES	B3GNT5 ABO	5.49e-04	26	19	2	M17377
Pathway	WP_COVID19_STRUCTURAL_COVERAGE_MAP	ACE2 AQR	5.49e-04	26	19	2	M48318
Pathway	WP_SARSCOV2_MITOCHONDRIAL_CHRONIC_OXIDATIVE_STRESS_AND_ENDOTHELIAL_DYSFUNCTION	ACE ACE2	5.92e-04	27	19	2	M45548
Pathway	WP_RAS_AND_BRADYKININ_PATHWAYS_IN_COVID19	ACE ACE2	6.84e-04	29	19	2	M40051
Pathway	WP_ANTIVIRAL_AND_ANTIINFLAMMATORY_EFFECTS_OF_NRF2_ON_SARSCOV2_PATHWAY	GUCY1A2 ACE2	8.33e-04	32	19	2	M42560
Pathway	WP_MITOCHONDRIAL_IMMUNE_RESPONSE_TO_SARSCOV2	ACE ACE2	8.86e-04	33	19	2	M40066
Pubmed	Myocardial infarction increases ACE2 expression in rat and humans.	ACE ACE2	4.18e-07	2	23	2	15671045
Pubmed	ACE and ACE2 Gene Variants Are Associated With Severe Outcomes of COVID-19 in Men.	ACE ACE2	4.18e-07	2	23	2	35250987
Pubmed	Type 1 diabetes is associated with significant changes of ACE and ACE2 expression in peripheral blood mononuclear cells.	ACE ACE2	4.18e-07	2	23	2	35260304
Pubmed	ACE2 gene expression is up-regulated in the human failing heart.	ACE ACE2	4.18e-07	2	23	2	15151696
Pubmed	Quantitative mRNA expression profiling of ACE 2, a novel homologue of angiotensin converting enzyme.	ACE ACE2	4.18e-07	2	23	2	12459472
Pubmed	Angiotensin-converting enzyme 2 (ACE2), but not ACE, is preferentially localized to the apical surface of polarized kidney cells.	ACE ACE2	4.18e-07	2	23	2	16166094
Pubmed	Characterization of ACE and ACE2 Expression within Different Organs of the NOD Mouse.	ACE ACE2	4.18e-07	2	23	2	28273875
Pubmed	Angiotensin-converting enzyme 2 protects from lethal avian influenza A H5N1 infections.	ACE ACE2	4.18e-07	2	23	2	24800825
Pubmed	Residues affecting the chloride regulation and substrate selectivity of the angiotensin-converting enzymes (ACE and ACE2) identified by site-directed mutagenesis.	ACE ACE2	4.18e-07	2	23	2	19021774
Pubmed	Angiotensin converting enzyme insertion/deletion genetic polymorphism: its impact on renal function in critically ill patients.	ACE ACE2	4.18e-07	2	23	2	19020433
Pubmed	The two fACEs of the tissue renin-angiotensin systems: implication in cardiovascular diseases.	ACE ACE2	4.18e-07	2	23	2	17504232
Pubmed	Distinct roles for angiotensin-converting enzyme 2 and carboxypeptidase A in the processing of angiotensins within the murine heart.	ACE ACE2	4.18e-07	2	23	2	18356559
Pubmed	Increased Angiotensin-Converting Enzyme 2 and Loss of Alveolar Type II Cells in COVID-19-related Acute Respiratory Distress Syndrome.	ACE ACE2	4.18e-07	2	23	2	34449302
Pubmed	Angiotensin-converting enzymes (ACE, ACE2) gene variants and COVID-19 outcome.	ACE ACE2	4.18e-07	2	23	2	32882331
Pubmed	The combination of ACE I/D and ACE2 G8790A polymorphisms revels susceptibility to hypertension: A genetic association study in Brazilian patients.	ACE ACE2	4.18e-07	2	23	2	31430320
Pubmed	Kidney and Lung ACE2 Expression after an ACE Inhibitor or an Ang II Receptor Blocker: Implications for COVID-19.	ACE ACE2	4.18e-07	2	23	2	32669323
Pubmed	Balance between angiotensin converting enzyme and angiotensin converting enzyme 2 in patients with chronic heart failure.	ACE ACE2	4.18e-07	2	23	2	25869724
Pubmed	Angiotensin-converting enzyme 2 is an essential regulator of heart function.	ACE ACE2	4.18e-07	2	23	2	12075344
Pubmed	Polymorphisms of ACE2 gene are associated with essential hypertension and antihypertensive effects of Captopril in women.	ACE ACE2	4.18e-07	2	23	2	17473847
Pubmed	Synergistic expression of angiotensin-converting enzyme (ACE) and ACE2 in human renal tissue and confounding effects of hypertension on the ACE to ACE2 ratio.	ACE ACE2	4.18e-07	2	23	2	17303661
Pubmed	Assessment of angiotensin converting enzyme gene polymorphism in preeclampsia mothers of Bangladesh.	ACE ACE2	4.18e-07	2	23	2	33241696
Pubmed	Angiotensin-converting enzyme (ACE) and ACE2 levels in the cerebrospinal fluid of patients with multiple sclerosis.	ACE ACE2	4.18e-07	2	23	2	19136547
Pubmed	Genotype variation of ACE and ACE2 genes affects the severity of COVID-19 patients.	ACE ACE2	4.18e-07	2	23	2	37667339
Pubmed	Levels of angiotensin-converting enzyme 1 and 2 in serum and urine of children with Sickle Cell Disease.	ACE ACE2	4.18e-07	2	23	2	33973994
Pubmed	Albumin caused the increasing production of angiotensin II due to the dysregulation of ACE/ACE2 expression in HK2 cells.	ACE ACE2	4.18e-07	2	23	2	19141296
Pubmed	Localization of ACE2 in the renal vasculature: amplification by angiotensin II type 1 receptor blockade using telmisartan.	ACE ACE2	4.18e-07	2	23	2	19004932
Pubmed	Global distribution of ACE1 (rs4646994) and ACE2 (rs2285666) polymorphisms associated with COVID-19: A systematic review and meta-analysis.	ACE ACE2	4.18e-07	2	23	2	36116608
Pubmed	A genome-wide association study identifies new loci for ACE activity: potential implications for response to ACE inhibitor.	ACE ABO	4.18e-07	2	23	2	20066004
Pubmed	Association investigations between ACE1 and ACE2 polymorphisms and severity of COVID-19 disease.	ACE ACE2	4.18e-07	2	23	2	36255490
Pubmed	Urinary mRNA expression of ACE and ACE2 in human type 2 diabetic nephropathy.	ACE ACE2	4.18e-07	2	23	2	18389211
Pubmed	Angiotensin-converting enzyme (ACE and ACE2) imbalance correlates with the severity of cerulein-induced acute pancreatitis in mice.	ACE ACE2	4.18e-07	2	23	2	24414175
Pubmed	Angiotensin converting enzymes ACE and ACE2 in thyroid cancer progression.	ACE ACE2	4.18e-07	2	23	2	31847529
Pubmed	Polymorphisms in the human angiotensin converting enzyme gene (ACE) linked to susceptibility of COVID-19 and malaria infections in the Ghanaian population.	ACE ACE2	4.18e-07	2	23	2	38367677
Pubmed	Sex dimorphism in ANGII-mediated crosstalk between ACE2 and ACE in diabetic nephropathy.	ACE ACE2	4.18e-07	2	23	2	29884907
Pubmed	No association of angiotensin-converting enzyme 2 gene (ACE2) polymorphisms with essential hypertension.	ACE ACE2	4.18e-07	2	23	2	15233982
Pubmed	A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase.	ACE ACE2	4.18e-07	2	23	2	10924499
Pubmed	Discrepancy between intrarenal messenger RNA and protein expression of ACE and ACE2 in human diabetic nephropathy.	ACE ACE2	4.18e-07	2	23	2	19077419
Pubmed	Angiotensin II regulates ACE and ACE2 in neurons through p38 mitogen-activated protein kinase and extracellular signal-regulated kinase 1/2 signaling.	ACE ACE2	4.18e-07	2	23	2	23535237
Pubmed	ACE/ACE2 balance might be instrumental to explain the certain comorbidities leading to severe COVID-19 cases.	ACE ACE2	4.18e-07	2	23	2	33442728
Pubmed	Are angiotensin converting enzyme (ACE1/ACE2) gene variants associated with the clinical severity of COVID-19 pneumonia? A single-center cohort study.	ACE ACE2	4.18e-07	2	23	2	35190362
Pubmed	Association of ACE1 I/D rs1799752 and ACE2 rs2285666 polymorphisms with the infection and severity of COVID-19: A meta-analysis.	ACE ACE2	4.18e-07	2	23	2	36148537
Pubmed	Combinatorial analysis of ACE and ACE2 polymorphisms reveals protection against COVID-19 worsening: A genetic association study in Brazilian patients.	ACE ACE2	4.18e-07	2	23	2	38032879
Pubmed	Expression of ACE and ACE2 in patients with hypertensive nephrosclerosis.	ACE ACE2	4.18e-07	2	23	2	21346373
Pubmed	Association of the insertion/deletion polymorphism of the angiotensin-converting enzyme gene with type 2 diabetes in two ethnic groups of Jerba Island in Tunisia.	ACE ACE2	4.18e-07	2	23	2	19286757
Pubmed	Polymorphisms of angiotensin-converting enzyme (ACE) and ACE2 are not associated with orthostatic blood pressure dysregulation in hypertensive patients.	ACE ACE2	4.18e-07	2	23	2	19684612
Pubmed	Identification of an alternative 5'-untranslated exon and new polymorphisms of angiotensin-converting enzyme 2 gene: lack of association with SARS in the Vietnamese population.	ACE ACE2	4.18e-07	2	23	2	15937940
Pubmed	Role of angiotensin-converting enzyme (ACE and ACE2) imbalance on tourniquet-induced remote kidney injury in a mouse hindlimb ischemia-reperfusion model.	ACE ACE2	4.18e-07	2	23	2	22580272
Pubmed	Assessment of ACE1 variants and ACE1/ACE2 expression in COVID-19 patients.	ACE ACE2	4.18e-07	2	23	2	34774774
Pubmed	Angiotensin-converting enzymes (ACE and ACE2) are downregulated in renal tumors.	ACE ACE2	4.18e-07	2	23	2	20692300
Pubmed	Effects of angiotensin-converting enzyme polymorphism on aortic elastic parameters in athletes.	ACE ACE2	4.18e-07	2	23	2	16088128
Pubmed	Role and Interaction Between ACE1, ACE2 and Their Related Genes in Cardiovascular Disorders.	ACE ACE2	4.18e-07	2	23	2	35245599
Pubmed	The impact of ACE2 polymorphisms (rs1978124, rs2285666, and rs2074192) and ACE1 rs1799752 in the mortality rate of COVID-19 in different SARS-CoV-2 variants.	ACE ACE2	4.18e-07	2	23	2	37328914
Pubmed	Gene polymorphisms in angiotensin I converting enzyme (ACE I/D) and angiotensin II converting enzyme (ACE2 C-->T) protect against cerebral malaria in Indian adults.	ACE ACE2	4.18e-07	2	23	2	20117248
Pubmed	Single Nucleotide Variants (SNVs) of Angiotensin-Converting Enzymes (ACE1 and ACE2): A Plausible Explanation for the Global Variation in COVID-19 Prevalence.	ACE ACE2	4.18e-07	2	23	2	37051471
Pubmed	Resveratrol Inhibits Growth of Experimental Abdominal Aortic Aneurysm Associated With Upregulation of Angiotensin-Converting Enzyme 2.	ACE ACE2	4.18e-07	2	23	2	28935757
Pubmed	SNPs of ACE1 (rs4343) and ACE2 (rs2285666) genes are linked to SARS-CoV-2 infection but not with the severity of disease.	ACE ACE2	4.18e-07	2	23	2	35305693
Pubmed	Novel findings: Expression of angiotensin-converting enzyme and angiotensin-converting enzyme 2 in thoracic aortic dissection and aneurysm.	ACE ACE2	4.18e-07	2	23	2	25237166
Pubmed	Effect of ACE2 and angiotensin-(1-7) in a mouse model of early chronic kidney disease.	ACE ACE2	1.25e-06	3	23	2	20357030
Pubmed	ACE and ACTN3 genotypes in older women: muscular phenotypes.	ACE ACE2	1.25e-06	3	23	2	21072744
Pubmed	Higher ACE2 expression levels in epicardial cells than subcutaneous stromal cells from patients with cardiovascular disease: Diabetes and obesity as possible enhancer.	ACE ACE2	1.25e-06	3	23	2	33251580
Pubmed	Gene polymorphisms and related risk factors in Mongolian hypertensive stroke patients.	ACE ACE2	1.25e-06	3	23	2	20831027
Pubmed	The Role of ACE, ACE2, and AGTR2 Polymorphisms in COVID-19 Severity and the Presence of COVID-19-Related Retinopathy.	ACE ACE2	1.25e-06	3	23	2	35885894
Pubmed	Gene polymorphisms predisposing to cardiac hypertrophy in patients with cardiac syndrome X.	ACE ACE2	1.25e-06	3	23	2	19051693
Pubmed	Host genetics and the profile of COVID-19 in indigenous people from the Brazilian Amazon: A pilot study with variants of the ACE1, ACE2 and TMPRSS2 genes.	ACE ACE2	1.25e-06	3	23	2	38307396
Pubmed	Angiotensin converting enzyme (ACE) and ACE2 bind integrins and ACE2 regulates integrin signalling.	ACE ACE2	1.25e-06	3	23	2	22523556
Pubmed	Association of angiotensin I converting enzyme, angiotensin II type 1 receptor and angiotensin I converting enzyme 2 gene polymorphisms with the dyslipidemia in type 2 diabetic patients of Chinese Han origin.	ACE ACE2	1.25e-06	3	23	2	21670585
Pubmed	CSF angiotensin II and angiotensin-converting enzyme levels in anti-aquaporin-4 autoimmunity.	ACE ACE2	1.25e-06	3	23	2	20541774
Pubmed	Gene variants rs5182, rs2074192, and rs4343 in the renin-angiotensin-aldosterone system are associated with symptom severity, higher odds of hospitalization, and death in COVID-19.	ACE ACE2	1.25e-06	3	23	2	38697603
Pubmed	Renin-angiotensin system (RAS) enzymes and placental trophoblast syncytialisation.	ACE ACE2	1.25e-06	3	23	2	35202745
Pubmed	Angiotensinogen and ACE gene polymorphisms and risk of atrial fibrillation in the general population.	ACE ACE2	1.25e-06	3	23	2	18496132
Pubmed	Investigation of ACE, ACE2 and AGTR1 genes for association with nephropathy in Type 1 diabetes mellitus.	ACE ACE2	1.25e-06	3	23	2	20854388
Pubmed	Downregulation of ACE, AGTR1, and ACE2 genes mediating SARS-CoV-2 pathogenesis by gut microbiota members and their postbiotics on Caco-2 cells.	ACE ACE2	1.25e-06	3	23	2	36174833
Pubmed	Embarking Effect of ACE2-Angiotensin 1-7/Mas Receptor Axis in Benign Prostate Hyperplasia.	ACE ACE2	1.25e-06	3	23	2	30055537
Pubmed	Brain angiotensin-converting enzymes: role of angiotensin-converting enzyme 2 in processing angiotensin II in mice.	ACE ACE2	1.25e-06	3	23	2	18263657
Pubmed	Association of ACE, ACE2 and UTS2 polymorphisms with essential hypertension in Han and Dongxiang populations from north-western China.	ACE ACE2	1.25e-06	3	23	2	16866021
Pubmed	ACE/ACE2 ratio and MMP-9 activity as potential biomarkers in tuberculous pleural effusions.	ACE ACE2	1.25e-06	3	23	2	23091417
Pubmed	Genetic polymorphisms of ACE1, ACE2, and TMPRSS2 associated with COVID-19 severity: A systematic review with meta-analysis.	ACE ACE2	1.25e-06	3	23	2	34997794
Pubmed	ACE and ACE2 activity in diabetic mice.	ACE ACE2	1.25e-06	3	23	2	16804085
Pubmed	Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolism.	ACE ACE2	2.51e-06	4	23	2	15283675
Pubmed	Pathological Ace2-to-Ace enzyme switch in the stressed heart is transcriptionally controlled by the endothelial Brg1-FoxM1 complex.	ACE ACE2	2.51e-06	4	23	2	27601681
Pubmed	Angiotensin-converting enzyme 2 protects from severe acute lung failure.	ACE ACE2	2.51e-06	4	23	2	16001071
Pubmed	Low renin-angiotensin system activity gene polymorphism and dysplasia associated with posterior urethral valves.	ACE ACE2	2.51e-06	4	23	2	16006956
Pubmed	Confirmation that the renin gene distal enhancer polymorphism REN-5312C/T is associated with increased blood pressure.	ACE ACE2	2.51e-06	4	23	2	20160196
Pubmed	Vascular wall ACE is not required for atherogenesis in ApoE(-/-) mice.	ACE ACE2	2.51e-06	4	23	2	19880118
Pubmed	A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9.	ACE ACE2	4.18e-06	5	23	2	10969042
Pubmed	Increased expression of the renin-angiotensin system and mast cell density but not of angiotensin-converting enzyme II in late stages of human heart failure.	ACE ACE2	6.26e-06	6	23	2	16962475
Pubmed	Interactions among related genes of renin-angiotensin system associated with type 2 diabetes.	ACE ACE2	6.26e-06	6	23	2	20592051
Pubmed	Neprilysin is a Mediator of Alternative Renin-Angiotensin-System Activation in the Murine and Human Kidney.	ACE ACE2	6.26e-06	6	23	2	27649628
Pubmed	Tissue-specific regulation of ACE/ACE2 and AT1/AT2 receptor gene expression by oestrogen in apolipoprotein E/oestrogen receptor-alpha knock-out mice.	ACE ACE2	6.26e-06	6	23	2	18192335
Pubmed	Genetic variation in angiotensin-converting enzyme-related pathways associated with sudden cardiac arrest risk.	ACE ACE2	1.17e-05	8	23	2	19716087
Pubmed	The effects of gestational age and maternal hypoxia on the placental renin angiotensin system in the mouse.	ACE ACE2	1.17e-05	8	23	2	25249154
Pubmed	Identification of genetic factors associated with susceptibility to angiotensin-converting enzyme inhibitors-induced cough.	ACE ACE2	7.10e-05	19	23	2	21052031
Pubmed	Perioperative genomic profiles using structure-specific oligonucleotide probes.	ACE ABO	1.05e-04	23	23	2	19474452
Pubmed	An atlas of genetic influences on human blood metabolites.	ACE DMBX1 ABO	2.62e-04	190	23	3	24816252
Pubmed	Human metabolic individuality in biomedical and pharmaceutical research.	ACE ABO	6.53e-04	57	23	2	21886157
GeneFamily	Olfactory receptors, family 10	OR10H3 OR10J5	1.72e-03	66	17	2	157
ToppCell	droplet-Liver-LIVER_HEP-30m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GNT5 GPR141 ACE PLK4	1.23e-06	158	23	4	91d265e95156f16459924d3e4dd11c180e164eee
ToppCell	droplet-Spleen-nan-3m-Hematologic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR141 ACE PPFIA4 FA2H	1.61e-06	169	23	4	972618e684321060c7af2429f853a6d639e8aae8
ToppCell	droplet-Spleen-nan-3m-Hematologic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR141 ACE PPFIA4 FA2H	1.61e-06	169	23	4	8e5e513090e86ca29fb61dfd388014774c506914
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GUCY1A2 ACE PPFIA4	6.13e-05	150	23	3	1270f33f9d7e46e55adf1a96e8beee858b95589d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GUCY1A2 ACE PPFIA4	6.13e-05	150	23	3	156118ce1d69522624196410cba18b8354cd0bb4
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_5\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PDK2 IKZF2 ABO	7.28e-05	159	23	3	08a1cd71eac4322fb313324f74fe8e37998f2d7d
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR141 ACE PPFIA4	7.28e-05	159	23	3	cdbccb83af6220bab300dfe56443ff69f6e2043a
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_5\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PDK2 IKZF2 ABO	7.28e-05	159	23	3	9bdfa7f5aa7753fe25b787bd43d694b6093d77eb
ToppCell	facs-Spleen-nan-3m-Hematologic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR141 ACE PPFIA4	7.56e-05	161	23	3	45591addc765760db6029ac19e80573373d1d917
ToppCell	facs-Spleen-nan-3m-Hematologic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR141 ACE PPFIA4	7.56e-05	161	23	3	8741b91a62c9a8ce377ef6533d323b65beb93c63
ToppCell	facs-Spleen-nan-3m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR141 ACE PPFIA4	7.56e-05	161	23	3	9cf1dcf0e7ca9e35c46c094a6b78f98d1f6b9276
ToppCell	Club-club-13\|World / Class top	GPR141 ACE2 ABCC3	7.70e-05	162	23	3	7d18f05a65ac715e62d610df9cc4a26539340dee
ToppCell	droplet-Liver-LIVER_HEP-30m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GNT5 GPR141 ACE	7.70e-05	162	23	3	93bd29c52846c3156b8b0d2e39c552373efdfe93
ToppCell	droplet-Spleen-nan-18m-Hematologic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR141 ACE PPFIA4	8.27e-05	166	23	3	e841e62cb20235d6233f78f4155fb8c0ffb1ef1b
ToppCell	droplet-Spleen-nan-18m-Hematologic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR141 ACE PPFIA4	8.27e-05	166	23	3	3ca3ddb663644f0e7f70f9b75833bb54cd9191d3
ToppCell	droplet-Spleen-nan-18m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR141 ACE PPFIA4	8.27e-05	166	23	3	f751cbd01d4978ded7755874ab60504f6291afd7
ToppCell	droplet-Spleen-SPLEEN-1m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR141 ACE PPFIA4	8.57e-05	168	23	3	f3b7a7df54988de77dcc7066e2fc1feb9c280b13
ToppCell	droplet-Spleen-nan-3m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR141 ACE PPFIA4	8.72e-05	169	23	3	91cfff1ad559cc327c6bb71c98aa29f0b3642568
ToppCell	droplet-Spleen-SPLEEN-1m-Hematologic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR141 ACE PPFIA4	8.88e-05	170	23	3	7cb7ad9ab064b6ea452545d145e5b1d4090cd4c1
ToppCell	droplet-Spleen-nan-21m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR141 ACE PPFIA4	8.88e-05	170	23	3	03cb4e508356f85372a588c8d1c6babf2a012683
ToppCell	droplet-Spleen-SPLEEN-1m-Hematologic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR141 ACE PPFIA4	8.88e-05	170	23	3	db7cee7e518debb2cbe9eeae05d47e14b69cb8e3
ToppCell	droplet-Liver-LIVER-NPC-1m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR141 ACE PPFIA4	9.19e-05	172	23	3	6aab59add5b180cee0ca31179c620e89d352d5c1
ToppCell	facs-Liver-Non-hepatocytes-24m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR141 ACE PPFIA4	9.19e-05	172	23	3	66823536288c7009ce01b5177794a3e874e94570
ToppCell	droplet-Liver-LIVER-NPC-1m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR141 ACE PPFIA4	9.19e-05	172	23	3	a125ac2db9c8ece95970a93aa6f7918d1dcef886
ToppCell	droplet-Tongue-Unstain-18m-Myeloid\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GNT5 GPR141 PPFIA4	9.51e-05	174	23	3	f2eb0199f59e1e2f46da344c05289876bd254fa3
ToppCell	droplet-Tongue-Unstain-18m-Myeloid-Langerhans_cell\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GNT5 GPR141 PPFIA4	9.51e-05	174	23	3	9019011eb8d9b7a95804fc11434f0fd42418103a
ToppCell	droplet-Tongue-Unstain-18m-Myeloid-Langerhans_cell\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GNT5 GPR141 PPFIA4	9.51e-05	174	23	3	deafbd0c2523afe09cc42f8c7b33945f3f5c00b4
ToppCell	3'-GW_trimst-1-LargeIntestine-Epithelial-Tuft-related-BEST4+_epithelial\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCC3 FA2H ABO	9.67e-05	175	23	3	8727252bcbc70bfa2ff72e7421df9cfe6fd4eed7
ToppCell	3'-GW_trimst-1-LargeIntestine-Epithelial-Tuft-related\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCC3 FA2H ABO	9.67e-05	175	23	3	c083abe368e5c0dc2b0f27f375c9271a2d7ff64f
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ACE ACE2 ABCC3	1.10e-04	183	23	3	d73cac83cde82665f110baad7cf28db75f9ffe52
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	ABCC3 PDK2 MED23	1.10e-04	183	23	3	310ad42b2b5d8ddd01d3a12db338f80ac1f5d08e
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ABCC3 PDK2 MED23	1.10e-04	183	23	3	fef51dcf180e6d4e136362c7e140ec5ef372e6d0
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	B3GNT5 FA2H IKZF2	1.29e-04	193	23	3	a5695ce2e24a62026ae28f3dea07ca4a435206b8
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 IKZF2 ABO	1.31e-04	194	23	3	04bfc555743f7d8821439d05ae442d15e9886c59
Drug	Ahtp-BK	ACE ACE2	9.76e-07	2	23	2	CID000128372
Drug	bradykinin potentiator c	ACE ACE2	9.76e-07	2	23	2	CID004597608
Drug	tebanyl	ACE ACE2	9.76e-07	2	23	2	CID000008609
Drug	isomartynoside	ACE ACE2	9.76e-07	2	23	2	CID006476337
Drug	2-nitrophenyl diethyl phosphate	ACE ACE2	9.76e-07	2	23	2	CID003014292
Drug	dansyltriglycine	ACE ACE2	9.76e-07	2	23	2	CID000194208
Drug	CV-5975	ACE ACE2	9.76e-07	2	23	2	CID003035825
Drug	EU-4881	ACE ACE2	9.76e-07	2	23	2	CID000146389
Drug	EU-4865	ACE ACE2	9.76e-07	2	23	2	CID000132472
Drug	A58365B	ACE ACE2	9.76e-07	2	23	2	CID000137366
Drug	A58365A	ACE ACE2	9.76e-07	2	23	2	CID000137365
Drug	MDL 27,788	ACE ACE2	9.76e-07	2	23	2	CID005748412
Drug	EU-5031	ACE ACE2	9.76e-07	2	23	2	CID000194686
Drug	BRL 36378	ACE ACE2	9.76e-07	2	23	2	CID000134835
Drug	chlorambucyl-proline	ACE ACE2	9.76e-07	2	23	2	CID000133596
Drug	AC1NNL9J	ACE ACE2	9.76e-07	2	23	2	CID005046512
Drug	DU-1227	ACE ACE2	9.76e-07	2	23	2	CID000156284
Drug	Ketoace	ACE ACE2	9.76e-07	2	23	2	CID000156271
Drug	I5b2	ACE ACE2	9.76e-07	2	23	2	CID000125070
Drug	MDL27,467A	ACE ACE2	9.76e-07	2	23	2	CID000194915
Drug	Lisinopril	ACE ACE2	9.76e-07	2	23	2	DB00722
Drug	Moexipril	ACE ACE2	9.76e-07	2	23	2	DB00691
Drug	Netilmicin sulfate [56931-57-2]; Up 200; 2.8uM; MCF7; HT_HG-U133A	GUCY1A2 TMEM259 ABCC3 PDK2 PPFIA4	1.37e-06	197	23	5	3524_UP
Drug	AC1Q5QTP	ACE ACE2 ABCC3	2.59e-06	27	23	3	CID000071324
Drug	AC1MJ2VJ	ACE ACE2	2.93e-06	3	23	2	CID003084602
Drug	WY-45,368	ACE ACE2	2.93e-06	3	23	2	CID000127103
Drug	CGS 13934	ACE ACE2	2.93e-06	3	23	2	CID000134126
Drug	BP1.137	ACE ACE2	2.93e-06	3	23	2	CID005311337
Drug	MC-838	ACE ACE2	2.93e-06	3	23	2	CID005488868
Drug	L-681,176	ACE ACE2	2.93e-06	3	23	2	CID000124628
Drug	ethyl glyoxalate	ACE ACE2	2.93e-06	3	23	2	CID000070211
Drug	Wf 10129	ACE ACE2	2.93e-06	3	23	2	CID003080984
Drug	MDL 27,088	ACE ACE2	2.93e-06	3	23	2	CID005489408
Drug	C112 Peptide	ACE ACE2	2.93e-06	3	23	2	CID000181457
Drug	C111 Peptide	ACE ACE2	2.93e-06	3	23	2	CID000181456
Drug	aladotril	ACE ACE2	2.93e-06	3	23	2	CID006450804
Drug	aladotrilat	ACE ACE2	2.93e-06	3	23	2	CID006450805
Drug	Rev 5975	ACE ACE2	2.93e-06	3	23	2	CID000127983
Drug	tert-butyl L-alaninate	ACE ACE2	2.93e-06	3	23	2	CID000089016
Drug	Utibaprilo	ACE ACE2	5.85e-06	4	23	2	CID000060359
Drug	Rac X 65	ACE ACE2	5.85e-06	4	23	2	CID005748390
Drug	AC1L9QEO	ACE ACE2	5.85e-06	4	23	2	CID000452589
Drug	BW-175	ACE ACE2	5.85e-06	4	23	2	CID000129247
Drug	Hoe 288	ACE ACE2	5.85e-06	4	23	2	CID000130318
Drug	Hoe 065	ACE ACE2	5.85e-06	4	23	2	CID000197279
Drug	Moveltipril [INN]	ACE ACE2	5.85e-06	4	23	2	CID005745793
Drug	Spiraprilate	ACE ACE2	9.74e-06	5	23	2	CID000134290
Drug	BW A575C	ACE ACE2	9.74e-06	5	23	2	CID000128240
Drug	dansylglycine	ACE ACE2	9.74e-06	5	23	2	CID000070666
Drug	AC1L1DX8	ACE ACE2	9.74e-06	5	23	2	CID000002546
Drug	Ace inhibitor BG-2	ACE ACE2	9.74e-06	5	23	2	CID000115370
Drug	2-oxo-4-phenylbutyric acid	ACE ACE2	9.74e-06	5	23	2	CID000069732
Drug	EXP132	ACE ACE2	9.74e-06	5	23	2	CID000132313
Drug	Locustamyotropin	ACE ACE2	9.74e-06	5	23	2	CID005748449
Drug	AC1L1SQ2	ACE ACE2	9.74e-06	5	23	2	CID000060183
Drug	FQp	ACE ACE2	9.74e-06	5	23	2	CID000001722
Drug	CGS 22989	ACE ACE2	9.74e-06	5	23	2	CID000130198
Drug	Enalkiren	ACE ACE2	9.74e-06	5	23	2	CID000060594
Drug	Secorvas	ACE ACE2 MED23	1.01e-05	42	23	3	CID000003419
Drug	Pro-val	ACE ACE2 ABO	1.42e-05	47	23	3	CID000142984
Drug	B 4146	ACE ACE2	1.46e-05	6	23	2	CID000128385
Drug	E 4177	ACE ACE2	1.46e-05	6	23	2	CID000131857
Drug	Du 1777	ACE ACE2	1.46e-05	6	23	2	CID003081108
Drug	Ab 47	ACE ACE2	1.46e-05	6	23	2	CID005487171
Drug	EXP3312	ACE ACE2	1.46e-05	6	23	2	CID000196704
Drug	AC1Q5KBJ	ACE ACE2	1.46e-05	6	23	2	CID000064925
Drug	Acrip	ACE ACE2	1.46e-05	6	23	2	CID000163664
Drug	Ala-Trp	ACE ACE2	1.46e-05	6	23	2	CID000085362
Drug	Leu-Gly-Pro	ACE ACE2	1.46e-05	6	23	2	CID000439585
Drug	AC1Q5R6K	ACE ACE2	1.46e-05	6	23	2	CID000114973
Drug	UP 269-6	ACE ACE2	1.46e-05	6	23	2	CID000132840
Drug	Ro 31-8472	ACE ACE2	1.46e-05	6	23	2	CID000132616
Drug	tasosartan	ACE ACE2	2.04e-05	7	23	2	CID000060919
Drug	octahydroindole-2-carboxylic acid	ACE ACE2	2.04e-05	7	23	2	CID003274680
Drug	VAL-TRP	ACE ACE2	2.04e-05	7	23	2	CID000168182
Drug	Pentoprilum	ACE ACE2	2.04e-05	7	23	2	CID000054938
Drug	zabicipril	ACE ACE2	2.04e-05	7	23	2	CID000071262
Drug	idrapril	ACE ACE2	2.72e-05	8	23	2	CID000065960
Drug	X x 5	ACE ACE2	2.72e-05	8	23	2	CID000448281
Drug	Boc-ca-phe	ACE ACE2	2.72e-05	8	23	2	CID005487215
Drug	Z-ca-gly-phe	ACE ACE2	2.72e-05	8	23	2	CID000195338
Drug	Abbott-81988	ACE ACE2	2.72e-05	8	23	2	CID000132387
Drug	EXP3880	ACE ACE2	2.72e-05	8	23	2	CID000132149
Drug	nolomirole	ACE ACE2	2.72e-05	8	23	2	CID000216238
Drug	zabiciprilat	ACE ACE2	2.72e-05	8	23	2	CID000065680
Drug	Muramyl pentapeptide	ACE ABO	2.72e-05	8	23	2	CID005492547
Drug	Neurotensin (1-10)	ACE ACE2	2.72e-05	8	23	2	CID003085266
Drug	CHEMBL1783187	ACE ACE2	3.50e-05	9	23	2	CID005230731
Drug	angiotensin I	ACE ACE2	3.50e-05	9	23	2	CID000447320
Drug	Leu-thiorphan	ACE ACE2	3.50e-05	9	23	2	CID000133576
Drug	Tryptophyltyrosine	ACE ACE2	3.50e-05	9	23	2	CID000088184
Drug	benazeprilat	ACE ACE2	3.50e-05	9	23	2	CID005463984
Drug	MDL 100,173	ACE ACE2	3.50e-05	9	23	2	CID000133986
Drug	norfuraneol	ACE ACE2	3.50e-05	9	23	2	CID004564493
Drug	Espirapril	ACE ACE2	3.50e-05	9	23	2	CID000091736
Drug	Glycopyrrolate [596-51-0]; Up 200; 10uM; MCF7; HT_HG-U133A	GUCY1A2 TMEM259 PDK2 PLK4	3.99e-05	194	23	4	4709_UP
Drug	Ethambutol dihydrochloride [1070-11-7]; Down 200; 14.4uM; PC3; HT_HG-U133A	GUCY1A2 TMEM259 ABCC3 FA2H	3.99e-05	194	23	4	4001_DN
Drug	Prednisone [53-03-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A	TMEM259 CCNT2 PDK2 TUBGCP3	4.07e-05	195	23	4	1478_DN
Drug	Homatropine hydrobromide (R,S) [51-56-9]; Up 200; 11.2uM; MCF7; HT_HG-U133A	PDK2 PLK4 TUBGCP3 MED23	4.15e-05	196	23	4	1684_UP
Drug	Pyrilamine maleate [59-33-6]; Up 200; 10uM; MCF7; HT_HG-U133A	GUCY1A2 ABCC3 PLK4 PPFIA4	4.23e-05	197	23	4	3184_UP
Disease	COVID-19 (is_implicated_in)	ACE ACE2 ABO	4.74e-07	21	22	3	DOID:0080600 (is_implicated_in)
Disease	angiotensin converting enzyme activity measurement	ACE ABO	5.31e-07	2	22	2	EFO_0004463
Disease	severe acute respiratory syndrome (is_implicated_in)	ACE2 ABO	1.11e-05	7	22	2	DOID:2945 (is_implicated_in)
Disease	N-palmitoylglycine measurement	DMBX1 FA2H	1.11e-05	7	22	2	EFO_0800342
Disease	angiotensin-converting enzyme measurement	ACE ABO	1.90e-05	9	22	2	EFO_0006515
Disease	leukemia (is_implicated_in)	ACE ABO	4.12e-05	13	22	2	DOID:1240 (is_implicated_in)
Disease	pneumonia (is_implicated_in)	ACE ABO	6.33e-05	16	22	2	DOID:552 (is_implicated_in)
Disease	hypertension (is_implicated_in)	ACE ACE2 ABO	9.78e-05	121	22	3	DOID:10763 (is_implicated_in)
Disease	Primary microcephaly	PLK4 TUBGCP3	1.21e-04	22	22	2	C0431350
Disease	primary biliary cholangitis (biomarker_via_orthology)	ACE ACE2	1.98e-04	28	22	2	DOID:12236 (biomarker_via_orthology)
Disease	cardioembolic stroke	PPFIA4 TUBGCP3 ABO	2.67e-04	170	22	3	EFO_1001976
Disease	lung disease (biomarker_via_orthology)	ACE ACE2	3.11e-04	35	22	2	DOID:850 (biomarker_via_orthology)
Disease	congestive heart failure (implicated_via_orthology)	ACE ACE2	4.28e-04	41	22	2	DOID:6000 (implicated_via_orthology)
Disease	Nodular glomerulosclerosis	ACE ACE2	4.28e-04	41	22	2	C0017667
Disease	ornithine measurement	ABO MED23	4.93e-04	44	22	2	EFO_0009776
Disease	Diabetic Nephropathy	ACE ACE2	4.93e-04	44	22	2	C0011881
Disease	cholestasis (biomarker_via_orthology)	ACE ABCC3	6.11e-04	49	22	2	DOID:13580 (biomarker_via_orthology)
Disease	diabetic retinopathy (is_implicated_in)	ACE ACE2	6.36e-04	50	22	2	DOID:8947 (is_implicated_in)
Disease	metabolite measurement	ACE ABCC3 FA2H ABO	7.15e-04	560	22	4	EFO_0004725
Disease	Acute Cerebrovascular Accidents	ACE ABO	7.42e-04	54	22	2	C0751956
Disease	pancreatic ductal carcinoma (is_marker_for)	ACE ACE2	9.46e-04	61	22	2	DOID:3587 (is_marker_for)
Disease	Cerebrovascular accident	ACE ABO	9.77e-04	62	22	2	C0038454
Disease	Coronary Arteriosclerosis	ACE ABO	1.07e-03	65	22	2	C0010054
Disease	Coronary Artery Disease	ACE ABO	1.07e-03	65	22	2	C1956346
Disease	myocardial infarction (implicated_via_orthology)	ACE ACE2	1.11e-03	66	22	2	DOID:5844 (implicated_via_orthology)
Disease	visceral:subcutaneous adipose tissue ratio	GUCY1A2 ADAM18	1.24e-03	70	22	2	EFO_0004767

Protein segments in the cluster

Peptide	Gene	Start	Entry
AIVYMHRFYMHHSFT	CCNT2	61	O60583
TAEKHFMVGHRVHYY	ABO	136	P16442
AHHEMGHIQYFMQYK	ACE	986	P12821
LHSVSPYFMMHCHYQ	ADAM18	81	Q9Y3Q7
YNMYMHLIQTTHHYH	AQR	1366	O60306
VSAMLHIHMYLTFLF	GPR141	91	Q7Z602
MMQSLILQHYYHYIF	ABCC3	361	O15438
IMPEAHSHYLYGHML	PPFIA4	1166	O75335
EMFSYRMHHIQPHYR	MED23	606	Q9ULK4
MVHFIHQMQYYITFE	TUBGCP3	711	Q96CW5
LDHVMYTIHMGCHGY	IKZF2	481	Q9UKS7
IHMVYVPSHLYHMLF	PDK2	236	Q15119
THSFLLMVMGYDHYV	OR10H3	111	O60404
SYYLIMLHFVMHGQH	FA2H	246	Q7L5A8
YHPCIYEKMMTSHGH	B3GNT5	311	Q9BYG0
MQHYGVNGYSLHAMN	DMBX1	1	Q8NFW5
TAHHEMGHIQYDMAY	ACE2	371	Q9BYF1
LFIQHSMIYFFHHYE	TMEM259	436	Q4ZIN3
IDHHLHTPMYFFLSM	OR10J5	51	Q8NHC4
MLHYFHPHHIVGFAM	GUCY1A2	236	P33402
INLHLMHTSYFLFVM	TMEM248	266	Q9NWD8
VMEHYVSMYIHGNLG	TADA2B	106	Q86TJ2
FMHQIITGMLYLHSH	PLK4	116	O00444