Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessregulation of mesenchymal stem cell differentiation

SOX6 SOX5 SLC4A11

2.92e-0611553GO:2000739
GeneOntologyBiologicalProcessmesenchymal stem cell differentiation

SOX6 SOX5 SLC4A11

6.40e-0614553GO:0072497
GeneOntologyBiologicalProcesspositive regulation of mesenchymal stem cell differentiation

SOX6 SOX5

4.17e-054552GO:2000741
DomainRibosomal_S26e

RPS26P11 RPS26

8.51e-062552IPR000892
DomainRIBOSOMAL_S26E

RPS26P11 RPS26

8.51e-062552PS00733
DomainRibosomal_S26e

RPS26P11 RPS26

8.51e-062552PF01283
DomainMYTH4

MYO7A MYO10

3.02e-049552PS51016
DomainMyTH4_dom

MYO7A MYO10

3.02e-049552IPR000857
DomainMyTH4

MYO7A MYO10

3.02e-049552PF00784
DomainMyTH4

MYO7A MYO10

3.02e-049552SM00139
DomainFERM_central

JAK2 MYO7A MYO10

4.04e-0449553IPR019748
DomainFERM_domain

JAK2 MYO7A MYO10

4.04e-0449553IPR000299
DomainFERM_1

JAK2 MYO7A MYO10

4.29e-0450553PS00660
DomainFERM_2

JAK2 MYO7A MYO10

4.29e-0450553PS00661
DomainFERM_3

JAK2 MYO7A MYO10

4.29e-0450553PS50057
DomainBand_41_domain

JAK2 MYO7A MYO10

4.29e-0450553IPR019749
DomainB41

JAK2 MYO7A MYO10

4.29e-0450553SM00295
DomainDOCK_C

DOCK1 DOCK10

4.60e-0411552IPR010703
DomainDHR-1_domain

DOCK1 DOCK10

4.60e-0411552IPR027007
DomainDHR_2

DOCK1 DOCK10

4.60e-0411552PS51651
DomainDHR_1

DOCK1 DOCK10

4.60e-0411552PS51650
DomainDOCK-C2

DOCK1 DOCK10

4.60e-0411552PF14429
DomainDHR-2

DOCK1 DOCK10

4.60e-0411552IPR027357
DomainDHR-2

DOCK1 DOCK10

4.60e-0411552PF06920
DomainDOCK

DOCK1 DOCK10

4.60e-0411552IPR026791
DomainDynein_heavy_chain_D4_dom

DNAH8 DNAH14

7.57e-0414552IPR024317
DomainDynein_HC_stalk

DNAH8 DNAH14

7.57e-0414552IPR024743
DomainMT

DNAH8 DNAH14

7.57e-0414552PF12777
DomainAAA_8

DNAH8 DNAH14

7.57e-0414552PF12780
DomainDHC_fam

DNAH8 DNAH14

8.72e-0415552IPR026983
DomainDynein_heavy_dom

DNAH8 DNAH14

8.72e-0415552IPR004273
DomainDynein_heavy

DNAH8 DNAH14

8.72e-0415552PF03028
DomainFurin_repeat

PCSK5 IGF1R

1.26e-0318552IPR006212
DomainFU

PCSK5 IGF1R

1.26e-0318552SM00261
DomaintRNA-bd_arm

SOX6 SOX5

2.25e-0324552IPR010978
DomainP-loop_NTPase

MYO7A MYO10 SULT1C3 SHPRH SMC4 RNF213 DNAH8 DNAH14

3.20e-03848558IPR027417
Domain-

CFAP54 TMTC4 IFIT3 P3H4

3.21e-032075541.25.40.10
DomainTPR-like_helical_dom

CFAP54 TMTC4 IFIT3 P3H4

4.89e-03233554IPR011990
DomainRA

RAPH1 MYO10

5.03e-0336552PF00788
DomainMyosin_head_motor_dom

MYO7A MYO10

5.59e-0338552IPR001609
DomainMYOSIN_MOTOR

MYO7A MYO10

5.59e-0338552PS51456
DomainMyosin_head

MYO7A MYO10

5.59e-0338552PF00063
DomainMYSc

MYO7A MYO10

5.59e-0338552SM00242
Domain-

MYO7A SULT1C3 SHPRH SMC4 RNF213 DNAH8 DNAH14

6.04e-037465573.40.50.300
DomainRA_dom

RAPH1 MYO10

6.18e-0340552IPR000159
DomainFERM_M

MYO7A MYO10

8.11e-0346552PF00373
DomainPH_dom-like

JAK2 RAPH1 MYO7A MYO10 DOCK10

8.23e-03426555IPR011993
Domain-

MYO7A MYO10

9.16e-03495521.20.80.10
DomainFERM/acyl-CoA-bd_prot_3-hlx

MYO7A MYO10

9.53e-0350552IPR014352
DomainTPR_2

TMTC4 IFIT3

9.53e-0350552PF07719
DomainTPR_2

TMTC4 IFIT3

9.53e-0350552IPR013105
DomainHMG_box

SOX6 SOX5

1.07e-0253552PF00505
DomainTPR_8

TMTC4 IFIT3

1.07e-0253552PF13181
DomainHMG_BOX_2

SOX6 SOX5

1.10e-0254552PS50118
DomainHMG

SOX6 SOX5

1.10e-0254552SM00398
Domain-

SOX6 SOX5

1.14e-02555521.10.30.10
Pubmed

Mechanism of STAT3 activation by insulin-like growth factor I receptor.

JAK2 IGF1R

2.73e-06258210747872
Pubmed

Generation of mice harboring a Sox5 conditional null allele.

SOX6 SOX5

2.73e-06258218543318
Pubmed

Accelerated up-regulation of L-Sox5, Sox6, and Sox9 by BMP-2 gene transfer during murine fracture healing.

SOX6 SOX5

2.73e-06258211585348
Pubmed

Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.

SOX6 ZNF462 SOX5 EFNA1 IGF1R RXRA

3.93e-0625158629031500
Pubmed

SoxD genes are required for adult neural stem cell activation.

SOX6 SOX5

8.19e-06358235108528
Pubmed

CircDOCK1 promotes the tumorigenesis and cisplatin resistance of osteogenic sarcoma via the miR-339-3p/IGF1R axis.

DOCK1 IGF1R

8.19e-06358234876132
Pubmed

The transcription factors SOX9 and SOX5/SOX6 cooperate genome-wide through super-enhancers to drive chondrogenesis.

SOX6 SOX5

8.19e-06358226150426
Pubmed

Generation of mice harboring a Sox6 conditional null allele.

SOX6 SOX5

8.19e-06358216652367
Pubmed

The combination of SOX5, SOX6, and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage.

SOX6 SOX5

8.19e-06358215529345
Pubmed

SOX trio decrease in the articular cartilage with the advancement of osteoarthritis.

SOX6 SOX5

8.19e-06358221728837
Pubmed

SOX5/6/21 Prevent Oncogene-Driven Transformation of Brain Stem Cells.

SOX6 SOX5

8.19e-06358228687615
Pubmed

Electroporation-mediated transfer of SOX trio genes (SOX-5, SOX-6, and SOX-9) to enhance the chondrogenesis of mesenchymal stem cells.

SOX6 SOX5

8.19e-06358221401405
Pubmed

Circular RNA DOCK1 promotes bladder carcinoma progression via modulating circDOCK1/hsa-miR-132-3p/Sox5 signalling pathway.

DOCK1 SOX5

8.19e-06358230983072
Pubmed

CFTR interactome mapping using the mammalian membrane two-hybrid high-throughput screening system.

ZNF462 AGBL4 AGO3 HHIPL2 DOCK10 CASQ2 CLEC12A

8.53e-0644058735156780
Pubmed

Hospicells promote upregulation of the ATP-binding cassette genes by insulin-like growth factor-I via the JAK2/STAT3 signaling pathway in an ovarian cancer cell line.

JAK2 IGF1R

1.64e-05458223857432
Pubmed

L-Sox5 and Sox6 drive expression of the aggrecan gene in cartilage by securing binding of Sox9 to a far-upstream enhancer.

SOX6 SOX5

1.64e-05458218559420
Pubmed

miR-23a-3p regulated by LncRNA SNHG5 suppresses the chondrogenic differentiation of human adipose-derived stem cells via targeting SOX6/SOX5.

SOX6 SOX5

1.64e-05458232960357
Pubmed

Vertebrate unconventional myosins.

MYO7A MYO10

1.64e-0545828690736
Pubmed

SHOX interacts with the chondrogenic transcription factors SOX5 and SOX6 to activate the aggrecan enhancer.

SOX6 SOX5

1.64e-05458221262861
Pubmed

Dynamic epigenetic mechanisms regulate age-dependent SOX9 expression in mouse articular cartilage.

SOX6 SOX5

1.64e-05458226806292
Pubmed

Sox9 family members negatively regulate maturation and calcification of chondrocytes through up-regulation of parathyroid hormone-related protein.

SOX6 SOX5

1.64e-05458219759178
Pubmed

The transcription factor Znf219 regulates chondrocyte differentiation by assembling a transcription factory with Sox9.

SOX6 SOX5

2.72e-05558220940257
Pubmed

Interaction of human suppressor of cytokine signaling (SOCS)-2 with the insulin-like growth factor-I receptor.

JAK2 IGF1R

2.72e-0555829727029
Pubmed

Nuclear insulin-like growth factor 1 receptor phosphorylates proliferating cell nuclear antigen and rescues stalled replication forks after DNA damage.

IGF1R SHPRH

2.72e-05558228924044
Pubmed

Interaction of Janus kinases JAK-1 and JAK-2 with the insulin receptor and the insulin-like growth factor-1 receptor.

JAK2 IGF1R

2.72e-0555829492017
Pubmed

Sox6 cell-autonomously stimulates erythroid cell survival, proliferation, and terminal maturation and is thereby an important enhancer of definitive erythropoiesis during mouse development.

SOX6 SOX5

2.72e-05558216627753
Pubmed

Kinase activation through dimerization by human SH2-B.

JAK2 IGF1R

2.72e-05558215767667
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

DOCK1 ZNF462 JAK2 EFNA1 IGF1R ARHGEF38 SHPRH RNF213 CSMD1 RXRA DNAH14

3.04e-051489581128611215
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

EFNA1 AGO3 RAPH1 MYO7A MYO10 SULT1C3 ARHGEF38 CSMD1 LRMDA DOP1B

3.57e-051242581030973865
Pubmed

L-Sox5 and Sox6 proteins enhance chondrogenic miR-140 microRNA expression by strengthening dimeric Sox9 activity.

SOX6 SOX5

4.08e-05658222547066
Pubmed

A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene.

SOX6 SOX5

4.08e-0565829755172
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

SOX6 ZNF462 ZDHHC21 SOX5 ZBTB33 ZIC5 RXRA DOP1B

5.63e-0580858820412781
Pubmed

Tails of unconventional myosins.

MYO7A MYO10

5.71e-05758211212352
Pubmed

The application of the polymerase chain reaction to cloning members of the protein tyrosine kinase family.

JAK2 IGF1R

5.71e-0575822482828
Pubmed

Pairing SOX off: with partners in the regulation of embryonic development.

SOX6 SOX5

5.71e-05758210729834
Pubmed

Runx1 and Runx2 cooperate during sternal morphogenesis.

SOX6 SOX5

5.71e-05758220181744
Pubmed

Genomewide association study of a rapid progression cohort identifies new susceptibility alleles for AIDS (ANRS Genomewide Association Study 03).

ZDHHC21 SOX5

5.71e-05758219754311
Pubmed

The transcription factor Sox5 modulates Sox10 function during melanocyte development.

SOX6 SOX5

7.60e-05858218703590
Pubmed

A conserved family of genes related to the testis determining gene, SRY.

SOX6 SOX5

7.60e-0585821614875
Pubmed

Transcription factors Sox5 and Sox6 exert direct and indirect influences on oligodendroglial migration in spinal cord and forebrain.

SOX6 SOX5

7.60e-05858226345464
Pubmed

Cytoneme delivery of Sonic Hedgehog from ligand-producing cells requires Myosin 10 and a Dispatched-BOC/CDON co-receptor complex.

MYO10 DISP1

7.60e-05858233570491
Pubmed

Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating IGF-1 signaling.

JAK2 IGF1R

9.77e-05958226692333
Pubmed

An Integrative Developmental Genomics and Systems Biology Approach to Identify an In Vivo Sox Trio-Mediated Gene Regulatory Network in Murine Embryos.

SOX6 SOX5

9.77e-05958228630873
Pubmed

Translational Control of Sox9 RNA by mTORC1 Contributes to Skeletogenesis.

SOX6 SOX5

9.77e-05958230008325
Pubmed

Physical and functional interaction of growth hormone and insulin-like growth factor-I signaling elements.

JAK2 IGF1R

9.77e-05958215044591
Pubmed

Essential role of Sox9 in the pathway that controls formation of cardiac valves and septa.

SOX6 SOX5

1.22e-041058215096597
Pubmed

From head to toes: the multiple facets of Sox proteins.

SOX6 SOX5

1.22e-041058210037800
Pubmed

An Atoh1-S193A Phospho-Mutant Allele Causes Hearing Deficits and Motor Impairment.

SCN11A MYO7A

1.49e-041158228729444
Pubmed

Sox9 is required for notochord maintenance in mice.

SOX6 SOX5

1.49e-041158216678811
Pubmed

Bmpr1a and Bmpr1b have overlapping functions and are essential for chondrogenesis in vivo.

SOX6 SOX5

1.49e-041158215781876
Pubmed

Hif-1alpha regulates differentiation of limb bud mesenchyme and joint development.

SOX6 SOX5

1.49e-041158217470636
Pubmed

Sox13 functionally complements the related Sox5 and Sox6 as important developmental modulators in mouse spinal cord oligodendrocytes.

SOX6 SOX5

1.78e-041258226525805
Pubmed

miRNAs control tracheal chondrocyte differentiation.

SOX6 SOX5

1.78e-041258221945074
Pubmed

SoxD transcription factor deficiency in Schwann cells delays myelination in the developing peripheral nervous system.

SOX6 SOX5

1.78e-041258234234180
Pubmed

Genome-wide association analysis identifies three psoriasis susceptibility loci.

RPS26 SPATA2

2.11e-041358220953189
Pubmed

SOX2-LIN28/let-7 pathway regulates proliferation and neurogenesis in neural precursors.

SOX6 SOX5

2.11e-041358223884650
Pubmed

HES factors regulate specific aspects of chondrogenesis and chondrocyte hypertrophy during cartilage development.

SOX6 SOX5

2.11e-041358227160681
Pubmed

The contribution of common genetic variation to nicotine and cotinine glucuronidation in multiple ethnic/racial populations.

SOX6 KCTD7

2.11e-041358225293881
Pubmed

Genetic analysis of interactions between the somitic muscle, cartilage and tendon cell lineages during mouse development.

SOX6 SOX5

2.11e-041358215634692
Pubmed

Neurog2 simultaneously activates and represses alternative gene expression programs in the developing neocortex.

SOX6 SOX5

2.11e-041358222735158
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

JAK2 MYO7A SMC4 RNF213 RPS26 DNAH14 DOP1B

2.18e-0473658729676528
Pubmed

Cytoneme signaling provides essential contributions to mammalian tissue patterning.

MYO10 DISP1

2.46e-041458238171360
Pubmed

Numerous members of the Sox family of HMG box-containing genes are expressed in developing mouse teeth.

SOX6 SOX5

2.46e-04145828921394
Pubmed

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.

DOCK1 DOCK10

2.46e-041458212432077
Pubmed

Cbfb2 Isoform Dominates More Potent Cbfb1 and Is Required for Skeletal Development.

SOX6 SOX5

2.83e-041558226890219
Pubmed

Synovial joint morphogenesis requires the chondrogenic action of Sox5 and Sox6 in growth plate and articular cartilage.

SOX6 SOX5

2.83e-041558220206616
Pubmed

Differential isoform expression and alternative splicing in sex determination in mice.

SOX6 SOX5

2.83e-041558230871468
Pubmed

Sox5 and Sox6 are needed to develop and maintain source, columnar, and hypertrophic chondrocytes in the cartilage growth plate.

SOX6 SOX5

2.83e-041558214993235
Pubmed

Misexpression of Sox9 in mouse limb bud mesenchyme induces polydactyly and rescues hypodactyly mice.

SOX6 SOX5

3.23e-041658217222543
Pubmed

Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice.

ZNF462 AGBL4

3.23e-041658216096065
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

ZDHHC21 JAK2 AGO3 TMTC4 COG7 RNF213 P3H4 WDR72

3.62e-04106158833845483
Pubmed

Musculoskeletal integration at the wrist underlies the modular development of limb tendons.

SOX6 SOX5

3.66e-041758226062940
Pubmed

Spatio-temporal expression of Sox genes in murine palatogenesis.

SOX6 SOX5

3.66e-041758227241892
Pubmed

Cbfb regulates bone development by stabilizing Runx family proteins.

SOX6 SOX5

3.66e-041758225262822
Pubmed

The cell-intrinsic requirement of Sox6 for cortical interneuron development.

SOX6 SOX5

4.11e-041858219709629
Pubmed

Intracellular biosynthesis of lipids and cholesterol by Scap and Insig in mesenchymal cells regulates long bone growth and chondrocyte homeostasis.

SOX6 SOX5

4.11e-041858229899135
Pubmed

Sox5 and Sox6 are required for notochord extracellular matrix sheath formation, notochord cell survival and development of the nucleus pulposus of intervertebral discs.

SOX6 SOX5

4.11e-041858212571105
Pubmed

Expression of Sox genes in tooth development.

SOX6 SOX5

4.11e-041858226864488
Pubmed

Variability in the common genetic architecture of social-communication spectrum phenotypes during childhood and adolescence.

DOCK1 SCN11A

4.59e-041958224564958
Pubmed

Molecular evolution of Sry and Sox gene.

SOX6 SOX5

5.09e-042058211404013
Pubmed

The transcription factors L-Sox5 and Sox6 are essential for cartilage formation.

SOX6 SOX5

5.09e-042058211702786
Pubmed

Synergistic co-regulation and competition by a SOX9-GLI-FOXA phasic transcriptional network coordinate chondrocyte differentiation transitions.

SOX6 SOX5

5.62e-042158229659575
Pubmed

HES1 is a novel downstream modifier of the SHH-GLI3 Axis in the development of preaxial polydactyly.

SOX6 SOX5

5.62e-042158234928956
Pubmed

Temporomandibular joint formation requires two distinct hedgehog-dependent steps.

SOX6 SOX5

5.62e-042158219815519
Pubmed

SOX6 controls dorsal progenitor identity and interneuron diversity during neocortical development.

SOX6 SOX5

5.62e-042158219657336
Pubmed

Multiple roles and interactions of Tbx4 and Tbx5 in development of the respiratory system.

SOX6 SOX5

5.62e-042158222876201
Pubmed

SOX9 is dispensable for the initiation of epigenetic remodeling and the activation of marker genes at the onset of chondrogenesis.

SOX6 SOX5

5.62e-042158230021842
Pubmed

SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function.

SOX6 SOX5

6.18e-042258217084361
Pubmed

Aberrant androgen action in prostatic progenitor cells induces oncogenesis and tumor development through IGF1 and Wnt axes.

JAK2 IGF1R

6.18e-042258235902588
Pubmed

Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs.

SOX6 SOX5

6.18e-042258227527664
Pubmed

Ets1 is required for proper migration and differentiation of the cardiac neural crest.

SOX6 SOX5

6.18e-042258220356956
Pubmed

Molecular genetics of successful smoking cessation: convergent genome-wide association study results.

SOX5 ARHGEF38 CSMD1

6.53e-0410158318519826
Pubmed

Single-cell RNA-sequencing analysis of the developing mouse inner ear identifies molecular logic of auditory neuron diversification.

SCN11A MYO7A

7.37e-042458235790771
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

ZBTB33 RAPH1 SMC4 RPS26

8.91e-0425658433397691
Pubmed

Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease.

ZNF462 BUB1 CASQ2 RPS26 DNAH14

1.05e-0346358527503909
Pubmed

Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays.

IGF1R PYGL

1.23e-033158214684825
Pubmed

RNA microarray analysis in prenatal mouse cochlea reveals novel IGF-I target genes: implication of MEF2 and FOXM1 transcription factors.

IGF1R MYO7A

1.31e-033258220111592
Pubmed

Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia.

SULT1C3 RXRA

1.31e-033258224954895
Pubmed

The giant spectrin βV couples the molecular motors to phototransduction and Usher syndrome type I proteins along their trafficking route.

MYO7A MYO10

1.31e-033258223704327
Pubmed

The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6.

SOX6 SOX5

1.40e-033358212414734
Cytoband13q32.3

TMTC4 ZIC5

4.04e-042359213q32.3
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

JAK2 MYO7A MYO10

2.27e-04504331293
GeneFamilyDyneins, axonemal

DNAH8 DNAH14

7.35e-0417432536
GeneFamilySRY-boxes

SOX6 SOX5

9.21e-0419432757
CoexpressionLAKE_ADULT_KIDNEY_C4_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S2

SOX6 AGBL4 IGF1R RNF213 LRMDA DNAH14

1.86e-06176556M39223
CoexpressionLAKE_ADULT_KIDNEY_C13_THICK_ASCENDING_LIMB

DOCK1 SOX6 AGBL4 IGF1R DNAH14

8.22e-06131555M39232
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_1000

MORC1 SOX6 ZNF462 SOX5 PCSK5 MYO10 COG7 SMC4 RNF213 RNF17 PRDM14

3.20e-068065211gudmap_developingGonad_e12.5_epididymis_1000
CoexpressionAtlasDevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_1000

MORC1 SOX5 AGO3 COG7 BUB1 SHPRH SMC4 RNF213 RNF17 DNAH8

1.58e-057765210gudmap_developingGonad_e14.5_ ovary_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#1_top-relative-expression-ranked_500

DOCK1 SOX5 ZBTB33 SHPRH SMC4 PREPL

2.08e-05231526gudmap_developingLowerUrinaryTract_e14.5_ bladder_500_k1
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#5_top-relative-expression-ranked_1000

DOCK1 SOX5 ZBTB33 MYO10 SHPRH SMC4 PREPL

4.91e-05397527gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000_k5
CoexpressionAtlasDevelopingGonad_P2_ovary_emap-30224_k-means-cluster#5_top-relative-expression-ranked_500

MORC1 SMC4 RNF17

7.18e-0533523gudmap_developingGonad_P2_ovary_500_k5
CoexpressionAtlasDevelopingGonad_P2_ovary_emap-30224_top-relative-expression-ranked_1000

MORC1 AGO3 MYO10 COG7 SMC4 RNF213 RNF17 DNAH8 DISP1

9.39e-05770529gudmap_developingGonad_P2_ovary_1000
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_1000

MORC1 SOX5 AGO3 COG7 SHPRH SMC4 RNF213 RNF17 DNAH8

1.20e-04795529gudmap_developingGonad_e16.5_ovary_1000
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SOX6 AGBL4 IGF1R LRMDA DNAH14 WDR72

1.61e-071945667002937e8903e037332a215d00fbc7c7843b33f2
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Necab1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SOX6 PCSK5 TMTC4 IFIT3 NXPH2

5.42e-0712656528fbe63f7bc628b32d8e86bf9e80657e776dd1cc
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC1-cDC1_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SOX6 JAK2 DOCK10 RPS26 CLEC12A

1.82e-0616156576c993a4533362db2250c88b3ee3ede55362d54e
ToppCellCOVID-19-kidney-PEC|COVID-19 / Disease (COVID-19 only), tissue and cell type

SOX6 AGBL4 CFAP54 SLC4A11 WDR72

2.24e-06168565a086c306be430adf0632ba53e98cd8014d2de330
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

SOX6 AGBL4 CFAP54 SLC4A11 WDR72

2.97e-06178565544379f5a6145429762258d426b876bb36c112f5
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 SOX6 ZNF462 MYO10 LRMDA

3.31e-061825658a8b08ac4bb3cba3541dbe234e088703842285b9
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 SOX6 ZNF462 MYO10 LRMDA

3.31e-06182565e36766309c4d96a90d213ce37d3acef1029a3fdc
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 SOX6 ZNF462 DOCK10 LRMDA

3.59e-06185565efc5d564f8793c751ba640aef60f761e4b081d3f
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-OPC|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 SOX6 ZNF462 DOCK10 LRMDA

3.59e-06185565fba2dc46cd98ab9c78e788959c2121aa10d148b2
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK1 ZNF462 CFAP54 DNAH14 SLC4A11

4.19e-06191565d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

SOX6 AGBL4 IGF1R LRMDA WDR72

4.30e-06192565e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX6 AGBL4 IGF1R DNAH14 WDR72

4.41e-061935653866667dd221612589ae50f5c52f73a183a49ce6
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX6 AGBL4 ARHGEF38 DNAH14 WDR72

4.52e-0619456593c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SOX6 AGBL4 ARHGEF38 DNAH14 WDR72

4.52e-061945655eaaa81f4b2535f983c424aaef00077089526a5c
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SOX6 AGBL4 ARHGEF38 DNAH14 WDR72

4.64e-061955656477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SOX6 AGBL4 ARHGEF38 DNAH14 WDR72

4.75e-061965656ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX6 AGBL4 ARHGEF38 DNAH14 WDR72

4.75e-06196565eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCellcontrol-CD163+_Monocytes_(Sample_ID1_d7)|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

JAK2 RNF213 IFIT3 CLEC12A RXRA

5.12e-06199565933201d32eda12a89660bdbae9114a95cc428a38
ToppCellTracheal-NucSeq-Stromal-Chondrocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SOX6 AGBL4 CFAP54 HHIPL2 PYGL

5.25e-06200565b5a54b9baf79aea01f76a161f0a39bbe87eb4945
ToppCellTracheal-NucSeq-Stromal-Chondrocytic-Chondrocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SOX6 AGBL4 CFAP54 HHIPL2 PYGL

5.25e-06200565f5bd0b30e478dac09f68c46b0781f5f2e7e3c693
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Necab1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SOX6 PCSK5 TMTC4 IFIT3

1.92e-05126564a4fc7ac4931d2fc8aa8196a62d809b698937aa9c
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac1_Htr1d|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SOX6 TMTC4 IFIT3 NXPH2

2.83e-05139564fe1657ef9aeda7c530dc7febcd3dcd0e1d5f8a48
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Pdlim5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SOX6 PCSK5 TMTC4 IFIT3

4.90e-05160564dd16ca90feb3ae88b6409d6c278b4765da565514
ToppCellmild_COVID-19_(asymptomatic)-B_intermediate|World / disease group, cell group and cell class (v2)

ZDHHC21 SOX5 RNF17 DNAH8

4.90e-051605646722934e153b72039c3c4308557d0ef879a30638
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Pdlim5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SOX6 PCSK5 TMTC4 IFIT3

5.02e-05161564bf70be1de418615b5442ec684552551edaf1f072
ToppCellE15.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SOX6 KCTD7 SOX5 P3H4

5.02e-051615649703b7e67d9fadb6129cad166bd01be915042e44
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 AGBL4 LRMDA WDR72

5.14e-05162564285e6d553f485fd9f1075c4e1b940da251b5ea35
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC1|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SOX6 JAK2 RPS26 CLEC12A

5.39e-051645645638d95c7cc5e59c4a7bda30268a904a01861a5f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 AGBL4 LRMDA WDR72

5.39e-051645646fb2136168f430babfeb81ca7e151ca7a8092ec4
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYO7A SMC4 DOCK10 CLEC12A

5.52e-051655641dcd6b8aa192baeaa1f7bb334843edab6049b96f
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYO7A SMC4 DOCK10 PYGL

6.34e-05171564845f312f8cbe29d820da25f0e6d75deb382bbfd8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 RAPH1 DOCK10 PYGL

6.49e-0517256408a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 RAPH1 DOCK10 PYGL

6.49e-05172564553701349444eb366df3c11f54bb093434f153c6
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-stromal_related|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CSMD1 RNF17 SLC4A11 WDR72

6.94e-051755642fbffcb843f364645b99d1211698d96092abc5ef
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-stromal_related-Germ|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CSMD1 RNF17 SLC4A11 WDR72

6.94e-05175564d0d5ae2a9357aa183ab720c891d86b80c9822930
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF462 CFAP54 CASQ2 SLC4A11

6.94e-05175564284fdc7a9d303636a637041846850d19d114861a
ToppCellRV-11._Adipocyte|RV / Chamber and Cluster_Paper

SOX5 PCSK5 AGBL4 PYGL

7.41e-05178564278bbea5cf8f0589f71675c7a3d00679391b5253
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX6 SOX5 AGBL4 RAPH1

7.57e-05179564d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCellMesenchymal_cells-Chondrocytes|Mesenchymal_cells / Lineage and Cell class

SOX6 SOX5 HHIPL2 DNAH14

7.74e-051805646e399368430ef3afa9ce1ef0ed90f614ccef9987
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX6 CFAP54 NXPH2 SLC4A11

7.90e-051815646956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 SOX6 ZNF462 LRMDA

8.07e-05182564a05e5978ef5f7fac7eeb2ba1c0103ea90d5e9136
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 SOX6 ZNF462 LRMDA

8.07e-05182564831b5ce46b41efe01c4db6016c2f43148611373d
ToppCellpdx-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

SOX6 ZNF462 RAPH1 MYO10

8.07e-051825647b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-OPC|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 SOX6 ZNF462 LRMDA

8.07e-051825643cc61f5f7ad4a81eba3daf65e122880b5af3adc0
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 SOX6 ZNF462 LRMDA

8.07e-051825645d909e4b5f662905bf1be9c686bbddc3e87d2be9
ToppCellB_cells-ABCs|B_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

SOX5 JAK2 DNAH8 IFIT3

8.25e-05183564bf9c6fe3ce4e44e4056027257eab8448c39c4fb8
ToppCellfacs-Aorta-Heart-3m-Myeloid-leukocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JAK2 BUB1 DOCK10 CLEC12A

8.25e-05183564062ec08d66c923f90fee771b1bf8d98bdc7e6c1b
ToppCellMild/Remission-B_intermediate-6|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ZDHHC21 SOX5 DOCK10 DNAH8

8.42e-051845643d4864605c812862cf8926e02370eea3b8ccf32f
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

SHPRH DOCK10 RNF213 DOP1B

8.60e-05185564a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 SOX6 ZNF462 LRMDA

8.60e-051855642e1766f1a972fecd670daaaf7eb2d3a404f121e7
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 SOX6 ZNF462 LRMDA

8.60e-051855647aaa8335b40927e3e8fdcede807cd521fc213a0d
ToppCelldroplet-Lung-LUNG-1m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO7A DOCK10 PYGL RXRA

8.60e-0518556453a5218c1e6eb12daccde3d6e02f337e2586d74c
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ZDHHC21 SOX5 ARHGEF38 DNAH14

8.78e-051865642ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SOX6 ZNF462 CFAP54 SLC4A11

8.78e-051865645c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

SHPRH DOCK10 RNF213 DOP1B

8.78e-051865648571956890fc9894d766ba294a28e376b4aba428
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SOX6 ZNF462 AGBL4 LRMDA

8.78e-05186564b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 SOX6 DOCK10 LRMDA

8.96e-05187564daff7ccd3f1924cf2b34d3aca3eccde245aaf371
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 SOX6 DOCK10 LRMDA

8.96e-051875645b7a1edee602e55d3400dc17dbb6b8aaa26defc0
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 LRMDA NXPH2 WDR72

9.15e-0518856458ccb31cdf43167872ef0fc737e6f9c51ee2e060
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF462 CFAP54 DNAH14 SLC4A11

9.15e-0518856463a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCellhuman_hepatoblastoma-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

DOCK1 ZNF462 IGF1R MYO10

9.15e-05188564b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D231|Adult / Lineage, Cell type, age group and donor

SOX6 ZDHHC21 SOX5 ARHGEF38

9.34e-05189564dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCelldroplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYO7A DOCK10 PYGL RXRA

9.34e-05189564b2542b6fcf7bc10d29158d42b03182a939ff135a
ToppCellControl-B_intermediate-6|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ZDHHC21 SOX5 DOCK10 RNF213

9.34e-0518956411cb9a16f1de8f60af2073ed7ea6d4f41c02f299
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 AGBL4 LRMDA WDR72

9.34e-05189564532aaf02b364c5c4f58a2021c7c21d86df3875c9
ToppCelldroplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYO7A DOCK10 PYGL RXRA

9.53e-05190564da58227565ad6a690828dd8554dd3670222f8582
ToppCellNeuron-Postmitotic-Inhibitory_Neuron|World / Primary Cells by Cluster

SOX6 TMTC4 RXRA NXPH2

9.73e-051915644dd9c8117c4499ed9bde127baf2598603a82080d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 JAK2 CASQ2 CSMD1

9.92e-05192564bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCellNeuron-Postmitotic-Inhibitory_Neuron-SST-MGE1|World / Primary Cells by Cluster

SOX6 TMTC4 RXRA NXPH2

9.92e-05192564bcc499f4c7ba2898ecd9c47bf68c92ed359b81ba
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 JAK2 CASQ2 CSMD1

9.92e-05192564b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SOX5 ARHGEF38 LRMDA DNAH14

9.92e-05192564fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX6 AGBL4 DNAH14 WDR72

1.01e-0419356482e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCellPCW_07-8.5|World / Celltypes from embryonic and fetal-stage human lung

SOX6 SMC4 NXPH2 DNAH14

1.03e-041945645759c83308df017f1faae248e9b85388e25254f0
ToppCellcontrol-CD163+_Monocytes_(Sample_ID1_d7)|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

JAK2 IFIT3 CLEC12A RXRA

1.05e-0419556419413dc6aa0010686cdfa0c750ef0a7a76caf308
ToppCellbackground-Endothelial_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

ZNF462 IGF1R MYO10 LRMDA

1.07e-04196564e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCellMild/Remission-B_intermediate-6|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ZDHHC21 SOX5 DOCK10 DNAH8

1.10e-041975645370dda4a25e3a53d6fe2c887b7dabd7a58462b4
ToppCellmild-Myeloid|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

PYGL IFIT3 CLEC12A RXRA

1.12e-04198564908746384e10c6b833bb3bc124045d7b0bfd73b5
ToppCellSevere-B_intermediate-6|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ZDHHC21 SOX5 DOCK10 DNAH8

1.12e-041985648402421dc060926e968efe39a4e907f1e8ae5b1f
ToppCellsevere|World / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

JAK2 RNF213 PYGL IFIT3

1.14e-04199564c24aacef7405700bc5d0b736a38feea12b7f17c8
ToppCellSevere-B_intermediate-6|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ZDHHC21 SOX5 DOCK10 DNAH8

1.14e-04199564bf6ebb63ab361d9d1946225894d7be433e9befab
ToppCellNeuronal-Inhibitory-iB-iB_3(PVALB-SST)-FRZB--L2-4|Neuronal / cells hierarchy compared to all cells using T-Statistic

SOX6 PCSK5 NXPH2 OR2W6P

1.16e-042005645ec469267747dce3601c1d8ad01af89fa5b29acc
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SOX6 ZNF462 MYO10 SMC4

1.16e-0420056438e681997913fcbc93f4e1715820e53844376eab
ToppCellBronchial-NucSeq-Stromal-Chondrocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SOX6 CFAP54 HHIPL2 PYGL

1.16e-04200564b7b9441fa7ab0d43741a2ebd5ec1a48d537c6d47
ToppCellNeuronal-Inhibitory-iB-iB_3(PVALB-SST)-FRZB|Neuronal / cells hierarchy compared to all cells using T-Statistic

SOX6 PCSK5 NXPH2 OR2W6P

1.16e-04200564e79d93d55b25804f2608185168da472301b6ebca
ToppCellSigmoid-Macrophage-LYVE1_Macrophage|Macrophage / Region, Cell class and subclass

JAK2 RAPH1 RPS26 IFIT3

1.16e-04200564cdb3f242d0c80b4eb9044f59156443e77fb81a1d
ToppCellsevere-immature_Neutrophil|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

IGF1R PYGL CLEC12A DOP1B

1.16e-04200564a9b87accdaa6956116ab82427e1330e8f007ef94
ToppCellBronchial-NucSeq-Stromal-Chondrocytic-Chondrocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SOX6 CFAP54 HHIPL2 PYGL

1.16e-042005647c673ad0ea503ebd196579684d25d5f9e6a41030
ToppCellNeuronal-Inhibitory-iB-iB_3(PVALB-SST)-FRZB-|Neuronal / cells hierarchy compared to all cells using T-Statistic

SOX6 PCSK5 NXPH2 OR2W6P

1.16e-04200564320d5a3a1e7da2fa8f1a164e29e180ec8ac9889c
ToppCell(6)_Macrophage-(61)_LYVE1_Macrophage|(6)_Macrophage / shred on Cell_type and subtype

JAK2 RAPH1 IFIT3

2.55e-049856330a9a2abd0487e818628db589d31f630ca4d894b
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Cbln4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SOX6 TMTC4 IFIT3

4.09e-04115563ac73aa06e617ed791c6ae9e38189bac74188c27b
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Rxfp1_Prdm8|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PRDM14 IFIT3 NXPH2

4.74e-041215632ae870f822488799cd0ad85e7f72af64e33a867f
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_ALM_Olfr111_Nxph1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PCSK5 SCN11A EFNA1

4.86e-04122563dba1c647172a11381efcb178a23808161908daa3
ToppCellVE-CD4-CD8_2|VE / Condition, Cell_class and T cell subcluster

SCN11A IGF1R MYO10

4.86e-041225636745035feaf807b6a6b9537ac9d5ee0e000196eb
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Sema3c|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SOX6 TMTC4 IFIT3

4.86e-04122563eae9d94f8510ac0f434942451d55c7260977b178
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Nr2f2_Necab1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SOX6 TMTC4 IFIT3

5.09e-04124563298ff8bd8f0459f44ce8a8aea889c6f1cf84ac5f
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Cbln4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SOX6 TMTC4 IFIT3

5.33e-0412656394bd9cfe982b41a3114885173eab55feb0fbbbae
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Nxph2_Wls|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SOX5 PCSK5 NXPH2

5.84e-0413056305d5a73acf1d7f75a79876b1a06d27c74a89b8a4
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_P2ry12|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PCSK5 SCN11A EFNA1

5.97e-0413156380630812f8894b9358d36dc2dd03fea7ee870502
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Col15a1_Pde1a|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DOCK10 CASQ2 PRDM14

6.38e-04134563d63fff23040eada31bc35ba1e05b7c6a663e0037
ToppCellControl-B_memory-6|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

DNAH8 SLC4A11 WDR72

6.66e-0413656394f23bef50c0beb54ed39b1a4b340f7aec4e75cd
DiseaseParoxysmal atrial fibrillation

ZNF462 SOX5 AGBL4 IGF1R CASQ2 LRMDA

6.40e-07156586C0235480
Diseasefamilial atrial fibrillation

ZNF462 SOX5 AGBL4 IGF1R CASQ2 LRMDA

6.40e-07156586C3468561
DiseasePersistent atrial fibrillation

ZNF462 SOX5 AGBL4 IGF1R CASQ2 LRMDA

6.40e-07156586C2585653
DiseaseAtrial Fibrillation

ZNF462 SOX5 AGBL4 IGF1R CASQ2 LRMDA

7.42e-07160586C0004238
DiseaseDrug habituation

DOCK1 AGBL4 CSMD1 LRMDA DNAH8

3.20e-06115585C0013170
DiseaseSubstance-Related Disorders

DOCK1 AGBL4 CSMD1 LRMDA DNAH8

3.20e-06115585C0236969
DiseaseDrug abuse

DOCK1 AGBL4 CSMD1 LRMDA DNAH8

3.20e-06115585C0013146
DiseaseDrug Use Disorders

DOCK1 AGBL4 CSMD1 LRMDA DNAH8

3.20e-06115585C0013222
DiseaseDrug Dependence

DOCK1 AGBL4 CSMD1 LRMDA DNAH8

3.20e-06115585C1510472
DiseaseSubstance Dependence

DOCK1 AGBL4 CSMD1 LRMDA DNAH8

3.20e-06115585C0038580
DiseaseSubstance Use Disorders

DOCK1 AGBL4 CSMD1 LRMDA DNAH8

3.20e-06115585C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

DOCK1 AGBL4 CSMD1 LRMDA DNAH8

3.20e-06115585C0029231
DiseasePrescription Drug Abuse

DOCK1 AGBL4 CSMD1 LRMDA DNAH8

3.20e-06115585C4316881
DiseaseSubstance abuse problem

DOCK1 AGBL4 CSMD1 LRMDA DNAH8

3.34e-06116585C0740858
Diseaseage at menarche

ZNF462 SOX5 EFNA1 IGF1R ZIC5 MYO10 RPS26 CSMD1

2.03e-05594588EFO_0004703
Diseaseatrial fibrillation

ZNF462 SOX5 AGBL4 IGF1R CASQ2 LRMDA

8.85e-05371586EFO_0000275
DiseaseDiamond-Blackfan anemia (implicated_via_orthology)

RPS26P11 RPS26

1.69e-0410582DOID:1339 (implicated_via_orthology)
DiseaseAlzheimer's disease (implicated_via_orthology)

SOX6 SOX5 IGF1R

1.96e-0457583DOID:10652 (implicated_via_orthology)
Diseasephosphatidylcholine 40:6 measurement

TMTC4 CSMD1

5.07e-0417582EFO_0010389
Diseaseneuritic plaque measurement

DOCK1 ZDHHC21 PCSK5 CSMD1 LRMDA

6.17e-04349585EFO_0006798
Diseasefacial asymmetry measurement

SOX5 MYO10

6.36e-0419582EFO_0009751
Diseasealbuminuria

EFNA1 CSMD1 LRMDA

8.51e-0494583EFO_0004285
Diseasecolon adenocarcinoma (is_marker_for)

JAK2 PCSK5

1.11e-0325582DOID:234 (is_marker_for)
DiseaseQRS-T angle

SOX5 CASQ2 LRMDA

1.20e-03106583EFO_0020097
Diseaseurate measurement, bone density

LRMDA DNAH8 PREPL NXPH2 DNAH14 SLC4A11

1.33e-03619586EFO_0003923, EFO_0004531
Diseasechronotype measurement

DOCK1 SOX6 ZNF462 SOX5 CSMD1 PREPL WDR72

1.66e-03882587EFO_0008328
Diseasesocial communication impairment

DOCK1 SCN11A

1.81e-0332582EFO_0005427
Diseasehyperuricemia

IGF1R WDR72

1.93e-0333582EFO_0009104

Protein segments in the cluster

PeptideGeneStartEntry
KEYKLALLQCYGRYL

CFAP54

141

Q96N23
RMPQLLAYYYKCHKV

COG7

216

P83436
KYHNDPRFISYCLKF

BUB1

61

O43683
FYLYKHRTRPKVQYN

CSMD1

3506

Q96PZ7
IKGPLEDIYKIYCYH

ARHGEF38

176

Q9NXL2
QYFREKYTLQLKYPH

AGO3

311

Q9H9G7
RKCTKYNAVYQILHY

DISP1

416

Q96F81
DYKLVQKVCPDYNYH

NXPH2

241

O95156
YRNKYKAPTDYCLVL

RAPH1

456

Q70E73
YLPYGSLRDYLQKHK

JAK2

931

O60674
TKHLCYCLYRPRKYL

MORC1

261

Q86VD1
LVNHYYCKRPIYEFK

KCTD7

271

Q96MP8
YKRYRCFVLYKLPNL

LRMDA

101

Q9H2I8
YCEKVFPLAEYRTKH

ZBTB33

526

Q86T24
YYPCYLKVSHRDILG

DOP1B

1326

Q9Y3R5
YLYRHNYCSKDKIPI

IGF1R

656

P08069
CLHYYYKLKNNTRIC

PCSK5

656

Q92824
YDRYAAVCKPLHYTI

OR2W6P

126

Q8NHA6
LKLYRTKLIYHTYCE

OR52A4P

171

A6NMU1
YLYTLEKVCQPLYNH

DNAH8

236

Q96JB1
VTVYGRKHCYRLYTK

MYO10

1466

Q9HD67
STKYCRPYRVYKNQI

DOCK10

661

Q96BY6
YIYPKHLKYDSQKCF

DOCK10

676

Q96BY6
YIRYLYKLCDLHKEC

DOCK1

1216

Q14185
YYYISKPIHQHEDRC

EFNA1

126

P20827
YLYHQIGCCYKAKVR

IFIT3

276

O14879
PKNVYYYRCPDHRKN

AGBL4

131

Q5VU57
DNKLYRVPISHKCAY

DNAH14

2031

Q0VDD8
LKKYDLLCLYYHEPV

CASQ2

46

O14958
PKFRHNRKFYIYYSC

HHIPL2

281

Q6UWX4
KSYYLCKQVRLQYEH

SEC14L6

266

B5MCN3
VYASLEAYCKHKYPE

RXRA

396

P19793
YQFKKSPYLHPCVRE

SLC4A11

576

Q8NBS3
YVARNPKDCLVSYYH

SULT1C3

136

Q6IMI6
YKYYRDKHLKYTPCV

PRDM14

411

Q9GZV8
CLPFIVKHAYNLYKE

TMEM217B

136

A0A494BZU4
YRPYCKKNPQHLYSF

SHPRH

881

Q149N8
SYDRYVAICKPLHYT

OR6C3

116

Q9NZP0
RLSKIHLEKYPNYKY

SOX6

676

P35712
NRLYVQYYHCTYKKR

CLEC12A

231

Q5QGZ9
DPCHFYIRKYSQIKD

RNF17

426

Q9BXT8
DYLYQPSYRKFIKLH

RNF213

1276

Q63HN8
AIKHRRKYPDCYYNL

TMTC4

576

Q5T4D3
AYHYDPCYKKSELHK

SPATA2

486

Q9UM82
AYVLPKLYVKLHYCV

RPS26P11

61

Q5JNZ5
RNPKHELTAKYLNYY

P3H4

171

Q92791
TLYILAYLHYCPRKR

SLC50A1

81

Q9BRV3
QPVRKKFSDCYIIHY

ERVK-8

181

P63133
EKATLPYRHTAICYY

WDR72

101

Q3MJ13
LLIHTRKKYYTCNYC

ZNF840P

296

A6NDX5
FRKKNHVCQYYIYEL

SMC4

316

Q9NTJ3
HKNYIKRYCPYQNIK

PREPL

616

Q4J6C6
HYYYFLPLKKRNLDL

ZDHHC21

156

Q8IVQ6
KHNELKPYKCQLCYY

ZNF462

2321

Q96JM2
KPYKCQLCYYETKHT

ZNF462

2326

Q96JM2
AYVLPKLYVKLHYCV

RPS26

61

P62854
YECKHTKINPDYNYT

SCN11A

326

Q9UI33
RLSKQHLEKYPDYKY

SOX5

611

P35711
TQQHYYDKCPKRVYY

PYGL

71

P06737
YYCKIRGCDKSYTHP

ZIC5

551

Q96T25
YQELPKYLRGYHKCT

MYO7A

2016

Q13402