Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	TPR DMXL2 DNAJC16 USP9X ADGRB2 DVL3 CBARP SYNPO RUVBL2 NDUFS1 RYR2 ADD3 MECR RPTOR PDE4DIP NAV3 PRKAR1A PRKAR1B FERMT2 GCN1 WNK2	2.53e-08	1139	151	21	36417873
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TPR DMXL2 CTTNBP2 ZNRD2 USP9X ADGRB2 SYNPO CCDC177 PPM1H NCOR2 MDN1 RPTOR PDE4DIP PRKAR1A SYN1 PRKAR1B ELAVL2 WNK2	2.24e-07	963	151	18	28671696
Pubmed	Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity.	ICOSLG CR2 CD19	3.20e-07	4	151	3	32142650
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	CUL1 ZNF326 DNAJC16 USP9X RUVBL2 NDUFS1 GTF3C3 ADD3 MDN1 SUPT6H TRA2A SAMM50 GCN1 STAG2	8.35e-07	638	151	14	33239621
Pubmed	Association of genetic variants with hemorrhagic stroke in Japanese individuals.	GPR135 RUVBL2 CHUK NCOR2 SDK1 TRAPPC9 WNK2	3.23e-06	143	151	7	20198315
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	MYT1L SNAPIN DMXL2 PDE7A USP9X PEG10 DVL3 SYNPO FTCD REV3L USP9Y DCAF5 ADD3 CHUK POLR3B TTC7B PDE4DIP NAV3 PRKAR1A	3.33e-06	1285	151	19	35914814
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	ILDR2 KRT1 DMXL2 CTTNBP2 USP9X SYNPO CCDC177 NDUFS1 ADD3 TTC7B HECW2 RPTOR PDE4DIP PRKAR1A SYN1 SAMM50 CROCC FERMT2 TRAPPC9 WNK2	4.18e-06	1431	151	20	37142655
Pubmed	The functional interactome landscape of the human histone deacetylase family.	TPR ZNF326 USP9X ADD3 NCOR2 MDN1 CROCC GCN1 STAG2	5.26e-06	289	151	9	23752268
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ANKRD13D MYO9B PIEZO1 ADGRB2 IPP REV3L PIKFYVE NCOR2 MDN1 RPTOR NBEAL2 EIF2B3 ZNF324B GCN1 TRAPPC9 WNK2 RAB11FIP3	6.78e-06	1105	151	17	35748872
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	USP9X CCDC177 PHKA1 NCOR2 TTC7B SUPT6H A2ML1 SCN9A NAV3 ELAVL2 TRAPPC9	7.94e-06	475	151	11	31040226
Pubmed	Ubiquitin-specific peptidase 9, X-linked (USP9X) modulates activity of mammalian target of rapamycin (mTOR).	USP9X RUVBL2 RPTOR	1.72e-05	12	151	3	22544753
Pubmed	The multiphosphorylation domain of the phosphorylase kinase alpha M and alpha L subunits is a hotspot of differential mRNA processing and of molecular evolution.	PHKA1 PHKA2	1.87e-05	2	151	2	8226841
Pubmed	Promoter for the regulatory type I beta subunit of the 3',5'-cyclic adenosine monophosphate-dependent protein kinase directs transgene expression in the central nervous system.	PRKAR1A PRKAR1B	1.87e-05	2	151	2	1448119
Pubmed	Snapin mediates incretin action and augments glucose-dependent insulin secretion.	SNAPIN PRKAR1A	1.87e-05	2	151	2	21356520
Pubmed	Ubiquitin-specific protease activity of USP9Y, a male infertility gene on the Y chromosome.	USP9X USP9Y	1.87e-05	2	151	2	12895410
Pubmed	Uncoupling CD21 and CD19 of the B-cell coreceptor.	CR2 CD19	1.87e-05	2	151	2	19706534
Pubmed	The Drosophila developmental gene fat facets has a human homologue in Xp11.4 which escapes X-inactivation and has related sequences on Yq11.2.	USP9X USP9Y	1.87e-05	2	151	2	8922996
Pubmed	X-linked liver glycogenosis type II (XLG II) is caused by mutations in PHKA2, the gene encoding the liver alpha subunit of phosphorylase kinase.	PHKA1 PHKA2	1.87e-05	2	151	2	8733133
Pubmed	B cells in T follicular helper cell development and function: separable roles in delivery of ICOS ligand and antigen.	ICOSLG CD19	1.87e-05	2	151	2	24610013
Pubmed	Neuropathic pain develops normally in mice lacking both Na(v)1.7 and Na(v)1.8.	SCN9A SCN10A	1.87e-05	2	151	2	16111501
Pubmed	A role for CD21/CD35 and CD19 in responses to acute septic peritonitis: a potential mechanism for mast cell activation.	CR2 CD19	1.87e-05	2	151	2	11120817
Pubmed	Usp9y (ubiquitin-specific protease 9 gene on the Y) is associated with a functional promoter and encodes an intact open reading frame homologous to Usp9x that is under selective constraint.	USP9X USP9Y	1.87e-05	2	151	2	12925892
Pubmed	cDNA cloning of a liver isoform of the phosphorylase kinase alpha subunit and mapping of the gene to Xp22.2-p22.1, the region of human X-linked liver glycogenosis.	PHKA1 PHKA2	1.87e-05	2	151	2	1372435
Pubmed	Intersection of the complement and immune systems: a signal transduction complex of the B lymphocyte-containing complement receptor type 2 and CD19.	CR2 CD19	1.87e-05	2	151	2	1702139
Pubmed	Coligation of the B cell receptor with complement receptor type 2 (CR2/CD21) using its natural ligand C3dg: activation without engagement of an inhibitory signaling pathway.	CR2 CD19	1.87e-05	2	151	2	15749857
Pubmed	Novel isozymes of cAMP-dependent protein kinase exist in human cells due to formation of RI alpha-RI beta heterodimeric complexes.	PRKAR1A PRKAR1B	1.87e-05	2	151	2	8407966
Pubmed	mTORC1-selective activation of translation elongation promotes disease progression in chronic lymphocytic leukemia.	CD19 RPTOR	1.87e-05	2	151	2	37775560
Pubmed	Salmonella Promotes Its Own Survival in B Cells by Inhibiting Autophagy.	CD19 RPTOR	1.87e-05	2	151	2	35805144
Pubmed	Patient-specific induced pluripotent stem cell properties implicate Ca2+-homeostasis in clinical arrhythmia associated with combined heterozygous RYR2 and SCN10A variants.	RYR2 SCN10A	1.87e-05	2	151	2	37122207
Pubmed	Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.	CTTNBP2 USP9X SAV1 USP9Y PHKA1 PHKA2 PDE4DIP PRKAR1A PRKAR1B GCN1	2.08e-05	432	151	10	23455922
Pubmed	The HIV-1 matrix protein p17 activates the transcription factors c-Myc and CREB in human B cells.	CD19 PRKAR1A PRKAR1B	2.22e-05	13	151	3	20402410
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	RUVBL2 GTF3C3 NCBP2 MDN1 SUPT6H PRKAR1A GCN1 STAG2	2.67e-05	272	151	8	31010829
Pubmed	Mapping of a liver phosphorylase kinase alpha-subunit gene on the mouse X chromosome.	PHKA1 PHKA2 GLRA2	2.82e-05	14	151	3	8432533
Pubmed	Fyn Regulates Binding Partners of Cyclic-AMP Dependent Protein Kinase A.	KRT77 PDE4DIP PRKAR1A PRKAR1B GCN1	3.01e-05	82	151	5	30274258
Pubmed	The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins.	ZNF326 NDUFS1 NCBP2 PHKA1 PHKA2 TRA2A ELAVL2	3.16e-05	203	151	7	35012549
Pubmed	Gene expression in the developing mouse retina by EST sequencing and microarray analysis.	NDUFS1 RYR2 ELAVL2 FERMT2 SLC4A5 STAG2	3.82e-05	142	151	6	11812828
Pubmed	Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.	RUVBL2 CHUK NCOR2 SDK1 TRAPPC9 WNK2	3.82e-05	142	151	6	19851296
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	CUL1 TPR ZNF326 USP9X DUOX2 RUVBL2 ZNF768 NDUFS1 GTF3C3 MDN1 SUPT6H STARD9 RPTOR PRKAR1A TRA2A SAMM50 GCN1 STAG2	4.95e-05	1425	151	18	30948266
Pubmed	TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.	CUL1 TPR KRT1 MYO9B USP9X PUM2 REV3L LIN52 RUVBL2 NDUFS1 NCBP2 BEND7 TRA2A CNN3	5.29e-05	922	151	14	27609421
Pubmed	CD19 can regulate B lymphocyte signal transduction independent of complement activation.	CR2 CD19	5.60e-05	3	151	2	11544305
Pubmed	The cell and molecular basis of mechanical, cold, and inflammatory pain.	SCN9A SCN10A	5.60e-05	3	151	2	18669863
Pubmed	IkappaB kinase alpha-mediated derepression of SMRT potentiates acetylation of RelA/p65 by p300.	CHUK NCOR2	5.60e-05	3	151	2	16382138
Pubmed	Sodium channels and mammalian sensory mechanotransduction.	SCN9A SCN10A	5.60e-05	3	151	2	22449024
Pubmed	Sodium channel Na(v)1.7 is essential for lowering heat pain threshold after burn injury.	SCN9A SCN10A	5.60e-05	3	151	2	22875917
Pubmed	The Gag protein PEG10 binds to RNA and regulates trophoblast stem cell lineage specification.	USP9X PEG10	5.60e-05	3	151	2	30951545
Pubmed	Altered Ig hypermutation pattern and frequency in complementary mouse models of DNA polymerase ζ activity.	REV3L CD19	5.60e-05	3	151	2	22547703
Pubmed	Genetic Analysis of SCN11A, SCN10A, and SCN9A in Familial Episodic Pain Syndrome (FEPS) in Japan and Proposal of Clinical Diagnostic Criteria.	SCN9A SCN10A	5.60e-05	3	151	2	38999942
Pubmed	Loss of the liver X receptor LXRα/β in peripheral sensory neurons modifies energy expenditure.	NR1H3 SCN10A	5.60e-05	3	151	2	26076474
Pubmed	Exclusion of catalytic and regulatory subunits of cAMP-dependent protein kinase as candidate genes for the defect causing cystic fibrosis.	PRKAR1A PRKAR1B	5.60e-05	3	151	2	3479018
Pubmed	TBK1 Knockdown Alleviates Axonal Transport Deficits in Retinal Ganglion Cells Via mTORC1 Activation in a Retinal Damage Mouse Model.	USP9X RPTOR	5.60e-05	3	151	2	37395713
Pubmed	A critical role for complement C3d and the B cell coreceptor (CD19/CD21) complex in the initiation of inflammatory arthritis.	CR2 CD19	5.60e-05	3	151	2	16210644
Pubmed	CD275-Independent IL-17-Producing T Follicular Helper-like Cells in Lymphopenic Autoimmune-Prone Mice.	ICOSLG IL17RA	5.60e-05	3	151	2	27183569
Pubmed	Role of complement-binding CD21/CD19/CD81 in enhancing human B cell protection from Fas-mediated apoptosis.	CR2 CD19	5.60e-05	3	151	2	14607925
Pubmed	Abnormal expression of voltage-gated sodium channels Nav1.7, Nav1.3 and Nav1.8 in trigeminal neuralgia.	SCN9A SCN10A	5.60e-05	3	151	2	19699781
Pubmed	CD19 is essential for B cell activation by promoting B cell receptor-antigen microcluster formation in response to membrane-bound ligand.	CR2 CD19	5.60e-05	3	151	2	18059271
Pubmed	The SNARE-associated component SNAPIN binds PUMILIO2 and NANOS1 proteins in human male germ cells.	SNAPIN PUM2	5.60e-05	3	151	2	19168546
Pubmed	Glucoamylase-like domains in the alpha- and beta-subunits of phosphorylase kinase.	PHKA1 PHKA2	5.60e-05	3	151	2	12876330
Pubmed	Synergistic regulation of serotonin and opioid signaling contributes to pain insensitivity in Nav1.7 knockout mice.	SCN9A SCN10A	5.60e-05	3	151	2	28074005
Pubmed	A kinase anchoring protein (AKAP) interaction and dimerization of the RIalpha and RIbeta regulatory subunits of protein kinase a in vivo by the yeast two hybrid system.	PRKAR1A PRKAR1B	5.60e-05	3	151	2	12634056
Pubmed	Impaired TLR9 responses in B cells from patients with systemic lupus erythematosus.	CR2 CD19	5.60e-05	3	151	2	29515028
Pubmed	Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1) in acute and inflammatory pain.	SCN9A SCN10A	5.60e-05	3	151	2	15314237
Pubmed	Complement component C3d-antigen complexes can either augment or inhibit B lymphocyte activation and humoral immunity in mice depending on the degree of CD21/CD19 complex engagement.	CR2 CD19	5.60e-05	3	151	2	16339538
Pubmed	Activation of melanoma differentiation-associated gene 5 causes rapid involution of the thymus.	IFIH1 CD19	5.60e-05	3	151	2	19414755
Pubmed	Yield of peripheral sodium channels gene screening in pure small fibre neuropathy.	SCN9A SCN10A	5.60e-05	3	151	2	30554136
Pubmed	Commensal bacteria modulate cullin-dependent signaling via generation of reactive oxygen species.	CUL1 CHUK	5.60e-05	3	151	2	17914462
Pubmed	Proteomic screening of glutamatergic mouse brain synaptosomes isolated by fluorescence activated sorting.	PPM1H PRKAR1A PRKAR1B	6.24e-05	18	151	3	24413018
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	SNAPIN DMXL2 CTTNBP2 PEG10 CCDC141 NDUFS1 SUPT6H PDE4DIP PRKAR1A STAG2	6.75e-05	497	151	10	23414517
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	TPR DMXL2 USP9X DVL3 RUVBL2 SYN1 FERMT2 GCN1 STAG2 CNN3	6.87e-05	498	151	10	36634849
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	SNAPIN DMXL2 PDE7A DNAJC16 PEG10 PIEZO1 CBARP NDUFS1 DCAF5 GTF3C3 ADD3 SLC4A2 MDN1 SUPT6H PRKAR1A PRKAR1B SAMM50 FERMT2	8.51e-05	1487	151	18	33957083
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	WWOX SYNPO LIN52 PPM1H SHKBP1 NCOR2 USF3 SUPT6H RPTOR NAXD SPACA6 PRKAR1B SAMM50 CROCC SLC4A5 STAG2 TRAPPC9 WNK2	8.65e-05	1489	151	18	28611215
Pubmed	Proximity labeling reveals dynamic changes in the SQSTM1 protein network.	CUL1 SAV1 CHUK SHKBP1 SAMM50 CROCC FERMT2 CNN3	8.74e-05	322	151	8	39098523
Pubmed	ADAM10-Mediated ICOS Ligand Shedding on B Cells Is Necessary for Proper T Cell ICOS Regulation and T Follicular Helper Responses.	ICOSLG CD19	1.12e-04	4	151	2	28814605
Pubmed	NCoR1 and SMRT play unique roles in thyroid hormone action in vivo.	NR1H3 NCOR2	1.12e-04	4	151	2	25421714
Pubmed	Evolution and diversity of mammalian sodium channel genes.	SCN9A SCN10A	1.12e-04	4	151	2	10198179
Pubmed	Protein kinase A regulates inflammatory pain sensitization by modulating HCN2 channel activity in nociceptive sensory neurons.	SCN10A PRKAR1A	1.12e-04	4	151	2	28767511
Pubmed	Cyclic nucleotide mapping of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels.	PRKAR1A PRKAR1B	1.12e-04	4	151	2	24605759
Pubmed	Inhibition of the Wnt/beta-catenin pathway by the WWOX tumor suppressor protein.	WWOX DVL3	1.12e-04	4	151	2	19465938
Pubmed	Dorsal root ganglia isolated from Nf1+/- mice exhibit increased levels of mRNA expression of voltage-dependent sodium channels.	SCN9A SCN10A	1.12e-04	4	151	2	22260870
Pubmed	Isolation of cDNA clones for the catalytic gamma subunit of mouse muscle phosphorylase kinase: expression of mRNA in normal and mutant Phk mice.	PHKA1 PHKA2	1.12e-04	4	151	2	3472241
Pubmed	IL-17-dependent fibroblastic reticular cell training boosts tissue protective mucosal immunity through IL-10-producing B cells.	CD19 IL17RA	1.12e-04	4	151	2	34919443
Pubmed	Analgesic targets identified in mouse sensory neuron somata and terminal pain translatomes.	SCN9A SCN10A	1.12e-04	4	151	2	39163201
Pubmed	Nedd4-2 haploinsufficiency causes hyperactivity and increased sensitivity to inflammatory stimuli.	SCN9A SCN10A	1.12e-04	4	151	2	27604420
Pubmed	Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons.	SCN9A SCN10A	1.12e-04	4	151	2	22531176
Pubmed	Phosphorylase Kinase Deficiency	PHKA1 PHKA2	1.12e-04	4	151	2	21634085
Pubmed	Nav1.7 as a chondrocyte regulator and therapeutic target for osteoarthritis.	SCN9A SCN10A	1.12e-04	4	151	2	38172636
Pubmed	The CD19/CD21 signal transducing complex of human B lymphocytes includes the target of antiproliferative antibody-1 and Leu-13 molecules.	CR2 CD19	1.12e-04	4	151	2	1383329
Pubmed	Alpha/beta-tubulin are A kinase anchor proteins for type I PKA in neurons.	PRKAR1A PRKAR1B	1.12e-04	4	151	2	19056362
Pubmed	Liver X Receptors Protect Dorsal Root Ganglia from Obesity-Induced Endoplasmic Reticulum Stress and Mechanical Allodynia.	NR1H3 SCN10A	1.12e-04	4	151	2	30304667
Pubmed	Tbx18 and Tbx15 null-like phenotypes in mouse embryos expressing Tbx6 in somitic and lateral plate mesoderm.	TBX15 TBX18	1.12e-04	4	151	2	20832395
Pubmed	Localization and quaternary structure of the PKA RIβ holoenzyme.	PRKAR1A PRKAR1B	1.12e-04	4	151	2	22797896
Pubmed	USP9X deubiquitylating enzyme maintains RAPTOR protein levels, mTORC1 signalling and proliferation in neural progenitors.	USP9X RPTOR	1.12e-04	4	151	2	28341829
Pubmed	CD19 signaling pathways play a major role for murine AIDS induction and progression.	CR2 CD19	1.12e-04	4	151	2	12421939
Pubmed	Boat, an AXH domain protein, suppresses the cytotoxicity of mutant ataxin-1.	ATXN1L NCOR2	1.12e-04	4	151	2	16121196
Pubmed	Transforming growth factor beta1 signaling via interaction with cell surface Hyal-2 and recruitment of WWOX/WOX1.	WWOX HYAL2	1.12e-04	4	151	2	19366691
Pubmed	Cleavage of phosphorylase kinase and calcium-free calmodulin by HIV-1 protease.	PHKA1 PHKA2	1.12e-04	4	151	2	1872871
Pubmed	The selection of marginal zone B cells differs from that of B-1a cells.	CR2 CD19	1.12e-04	4	151	2	14662849
Pubmed	Biological pathway-based genome-wide association analysis identified the vasoactive intestinal peptide (VIP) pathway important for obesity.	CHUK PRKAR1A PRKAR1B	1.33e-04	23	151	3	20379146
Pubmed	Regulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα.	ZNF326 USP9X ZNF768 NDUFS1 CHUK TRA2A	1.50e-04	182	151	6	32239614
Pubmed	mTORC2 Assembly Is Regulated by USP9X-Mediated Deubiquitination of RICTOR.	USP9X RPTOR	1.86e-04	5	151	2	33378666
Pubmed	Ataxin-1 regulates B cell function and the severity of autoimmune experimental encephalomyelitis.	ATXN1L CD19	1.86e-04	5	151	2	32878998
GeneFamily	Immunoglobulin like domain containing	OSCAR CCDC141 HMCN2 CD19 CEACAM18 SDK1	7.11e-04	193	100	6	594
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN9A SCN10A	1.06e-03	9	100	2	1203
ToppCell	COVID-19_Mild-Lymphoid_B-B_intermediate\|COVID-19_Mild / Disease group, lineage and cell class	ICOSLG CNFN SYNPO CR2 CCDC141 PIKFYVE CD19	4.54e-06	194	151	7	bf6f72a489c62cbf1a679552d8c5eaaaa0b99d33
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-B-B_intermediate\|COVID-19_Mild / Disease, condition lineage and cell class	ICOSLG CNFN SYNPO CR2 CCDC141 PIKFYVE CD19	5.37e-06	199	151	7	1c6a08d01f6c1a2a4b6587d3a4522efbd03275e1
ToppCell	Kidney-Keratinocytes\|Kidney / Skin and Kidney Cells in Lupus Nephritis Patients.	KRT1 CNFN CLIC3 GNLY USP9Y KRT77 A2ML1	5.55e-06	200	151	7	41d83faa9f45ee7ea2ab19be8ecc6d2c5ac7fe5d
ToppCell	mild-B_intermediate\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ICOSLG CNFN SYNPO CR2 CCDC141 PIKFYVE CD19	5.55e-06	200	151	7	8e3132a1fe3708f725c5c4077878fb87bbea3678
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNFN USP9Y MOV10L1 SCN9A SCN10A WNK2	1.02e-05	145	151	6	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MOV10L1 SCN9A SCN10A NAV3 CNGA2 WNK2	1.67e-05	158	151	6	f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MOV10L1 SCN9A SCN10A NAV3 CNGA2 WNK2	1.67e-05	158	151	6	8c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCell	facs-Lung-nan-3m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AADAC PEG10 SHC4 RYR2 KRT77 WNK2	1.79e-05	160	151	6	f2cdee5a9e3b0eb125d6be7b5d239eb04333ae41
ToppCell	facs-Heart-LV-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYT1L CCDC169 DMXL2 SLC28A3 BST1 CROCC	2.13e-05	165	151	6	84eca6a0f5e996b6955ae79fa102af239098fe8f
ToppCell	facs-Heart-LV-3m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYT1L CCDC169 DMXL2 SLC28A3 BST1 CROCC	2.13e-05	165	151	6	af59a095ecc6758abc13d763c00e44447c488167
ToppCell	moderate-Myeloid-Mast_cell\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	KRT1 CTTNBP2 ADGRB2 CCDC141 FERMT2 VWA5B1	2.21e-05	166	151	6	c3835b424c63bf11a4e2c47635dc3787fc4a637a
ToppCell	B_cells-pDCs\|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis	DMXL2 CLIC3 MCTP1 BST1 VASH2 SCN9A	3.06e-05	176	151	6	ce757de9e09a225f3f96433f103f43619b0e0dda
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DMXL2 WWOX PHF19 NR1H3 BST1 GCN1	3.16e-05	177	151	6	1d5a071157c755f3a27a5c3143015da04ee0b0dc
ToppCell	15-Distal-Epithelial-Epithelial\|Distal / Age, Tissue, Lineage and Cell class	MYT1L CNFN FGF17 CHUK PPM1L ELAVL2	3.48e-05	180	151	6	99e2db9ad8e09fedc3542233553acece69f579f1
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	PIEZO1 CLIC3 SYNPO FNDC1 NBEAL2 ST6GALNAC5	3.93e-05	184	151	6	c7073d1b2c4fdb154d87678b92a0629c02116972
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)\|343B / Donor, Lineage, Cell class and subclass (all cells)	CLIC3 SYNPO NCOR2 FNDC1 NBEAL2 ST6GALNAC5	3.93e-05	184	151	6	cb15d6bae52c5ec251c2235859dc7e65f630ae23
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	PIEZO1 CLIC3 SYNPO FNDC1 NBEAL2 ST6GALNAC5	3.93e-05	184	151	6	1ed558a88215b248431c524ea16f13d9022ae98c
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	CLIC3 SYNPO NCOR2 FNDC1 NBEAL2 ST6GALNAC5	3.93e-05	184	151	6	bde4eaabd3e9bdaed23867d23a919b9d84b52d4b
ToppCell	Globus_pallidus-Neuronal\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MYT1L CBARP RYR2 GLRA2 SYN1 PRKAR1B	4.70e-05	190	151	6	416de85d8841dac883faa6f5339b2fb461a09e82
ToppCell	COVID_vent-Lymphocytic-B_cell\|COVID_vent / Disease condition, Lineage, Cell class and subclass	ICOSLG SAV1 SYNPO CR2 PIKFYVE CD19	4.70e-05	190	151	6	40b5e9e8f8fd8d84cb5b43e67b49267082348e9f
ToppCell	COVID_vent-Lymphocytic-B_cell-\|COVID_vent / Disease condition, Lineage, Cell class and subclass	ICOSLG SAV1 SYNPO CR2 PIKFYVE CD19	4.70e-05	190	151	6	a37a32dc1b931562a6660074e19d5598efc65284
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-0\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ICOSLG PEG10 SAV1 SYNPO CR2 CD19	4.84e-05	191	151	6	5a9a592875fbd0b1429b48db29a760fdc9c2c856
ToppCell	Adult-Immune-alveolar_macrophage_(MARCO_positive)-D175\|Adult / Lineage, Cell type, age group and donor	DMXL2 MYO9B OSCAR NR1H3 TTC7B PDE4DIP	4.98e-05	192	151	6	733491e932350e3c216a626cc49c3cd3fe970a82
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	DNAJC16 USP9X NDUFS1 GTF3C3 USF3 STAG2	5.12e-05	193	151	6	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SYNPO TMTC1 MCTP1 HMCN2 HYAL2 IMPG2	5.12e-05	193	151	6	cc355b2ed6510619cad969ae074126d7c8db784d
ToppCell	COVID-19-Fibroblasts-Alveolar_FB\|COVID-19 / group, cell type (main and fine annotations)	CTTNBP2 COL6A6 RYR2 ST6GALNAC5 NAV3 SDK1	5.43e-05	195	151	6	603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SDR42E1 RYR2 HMCN2 MOV10L1 VASH2 SDK1	5.58e-05	196	151	6	614a07334707eafe238d5cb7b080a3ca796a1920
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Dendritic_cell-DC_2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CTTNBP2 NDST2 OSCAR CR2 CD19 IL17RA	5.58e-05	196	151	6	8862964090f9a679a548103bfbb12e91295aae62
ToppCell	control-B_naive\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ICOSLG CNFN PEG10 SAV1 CR2 CD19	5.74e-05	197	151	6	559650fb53f18ecae4cfaa8221e978ae3fb63e06
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ICOSLG CNFN SAV1 SYNPO CR2 CD19	5.74e-05	197	151	6	f7a8440d2b8b17d9726c6fe3dd383effbfebab13
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TBX15 CBARP RYR2 TBX18 HMCN2 SDK1	5.74e-05	197	151	6	cfb3dc4b401800e33c82cfc3baee69dbbd16ac8c
ToppCell	COVID-19_Severe-Lymphoid_B\|COVID-19_Severe / Disease group, lineage and cell class	ICOSLG CNFN PEG10 SYNPO CR2 CD19	5.74e-05	197	151	6	25303329b051831cf2ed4df68f3948308e5fbd96
ToppCell	COVID-19_Mild-Lymphoid_B\|COVID-19_Mild / Disease group, lineage and cell class	ICOSLG CNFN PEG10 SAV1 CR2 CD19	5.74e-05	197	151	6	ff25c0e184bd0f068014bc3f5eba3aee17511b87
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	ICOSLG CNFN SAV1 SYNPO CR2 CD19	5.74e-05	197	151	6	7cae4f3eabfebce101de7bb7defb17d6c5360b58
ToppCell	Lung_Parenchyma-Control-Myeloid-Mast_cell\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CCDC169 KRT1 CTTNBP2 PTPN7 PRKAR1B ELAVL2	5.91e-05	198	151	6	0af55f2b859e4626e23e2733bf9ae2ace4547079
ToppCell	Lung_Parenchyma-Control-Myeloid-Mast_cell-Mast_cells-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CCDC169 KRT1 CTTNBP2 PTPN7 PRKAR1B ELAVL2	5.91e-05	198	151	6	f75800b4f3cf0d493226db8db7c949caade0ff90
ToppCell	Parenchyma_Control_(B.)-Immune-TX-Mast_cells\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	CCDC169 KRT1 CTTNBP2 PTPN7 PRKAR1B ELAVL2	5.91e-05	198	151	6	45089e0adf2c00f4b0bccd701f4daebf25858006
ToppCell	Lung_Parenchyma-Control-Myeloid-Mast_cell-Mast_cells\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CCDC169 KRT1 CTTNBP2 PTPN7 PRKAR1B ELAVL2	5.91e-05	198	151	6	4163220f4ccb825a8399298cfac8411eb2acc9a2
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	MYT1L PDE4DIP VASH2 SYN1 ELAVL2 C2orf80	6.07e-05	199	151	6	77b4aa00f14b86ef5db0490be98787e063979541
ToppCell	Influenza\|World / Disease, condition lineage and cell class	DMXL2 OSCAR SHKBP1 BST1 NBEAL2 IL17RA	6.24e-05	200	151	6	df996c35907a1c9194b9e2ca30e81f520ca067f0
ToppCell	mild-B_intermediate\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ICOSLG SYNPO CR2 CCDC141 PIKFYVE CD19	6.24e-05	200	151	6	fe815824e9e4be3f3db73610e3814a7fd533da65
ToppCell	Control-Control-Lymphocyte-B\|Control / Disease, condition lineage and cell class	ICOSLG PEG10 SAV1 SYNPO CR2 CD19	6.24e-05	200	151	6	d95551392de7316b72eacf1e4a1cb23452991fa0
ToppCell	severe-B_naive\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ICOSLG PEG10 SAV1 CR2 CD19 CNN3	6.24e-05	200	151	6	306df1f498ac2188eaf9f2a8d002bb73bdb9642d
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	CR2 FNDC1 NKX6-3 CEACAM18	7.47e-05	66	151	4	88afd3ab91774ce01ff4277395b7b59dbb23200a
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_B0\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ILDR2 KRT1 SHC4 GNLY BEND7	9.07e-05	133	151	5	386c9bbd9bab62209a67ebae6cd6ac0d7cef0a2d
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Crh\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CCDC141 GLRA2 SCN10A C2orf80 SDK1	1.01e-04	136	151	5	44f03e4f55fb2c5f8b9397142c89f7194b009cc6
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SHC4 CR2 ENAM UMODL1 VWA5B1	1.32e-04	144	151	5	cc11cce43d1af8ac63140d05faf215ae9a10cde1
ToppCell	facs-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	AADAC PHF19 RYR2 KRT77 WNK2	1.50e-04	148	151	5	5983c4546f527a0b599cfcbd8a6cb937a1d6f895
ToppCell	COVID-19_Severe-B_cell\|World / disease group, cell group and cell class	ICOSLG CR2 MDN1 CD19 SH2D7	1.55e-04	149	151	5	9a9fcbf7e8a6811958f3fd2d36315e19ab2b1127
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-NP\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CNFN FTCD TMTC1 GLRA2 C2orf80	1.59e-04	150	151	5	2ba55e51877e2e749cccdae7df5d885dc55b2587
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-9\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ICOSLG CNFN PEG10 CR2 CD19	1.59e-04	150	151	5	d9931507257c64ead4a53786e6822f51962c6015
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PEG10 NDST2 NAV3 CNN3 IMPG2	1.59e-04	150	151	5	909ccab92855f5f049dc29593aadab1ea973297b
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-myeloid-myeloid_granulocytic\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	KRT1 CTTNBP2 NDST2 PPM1H TTC7B	1.70e-04	152	151	5	32634195048858ae84605c61e43c542d90f7cab5
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-myeloid-myeloid_granulocytic-mast_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	KRT1 CTTNBP2 NDST2 PPM1H TTC7B	1.70e-04	152	151	5	0eb185b2404f015efff1bd140e0c502d714720fb
ToppCell	PND07-28-samps-Mesenchymal-Mesothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	TBX15 ILDR2 NKX6-2 RYR2 PPM1L	1.91e-04	156	151	5	574f761962a7dd3308bd41fc529dd3ea1b8625f8
ToppCell	PND07-28-samps-Mesenchymal-Mesothelial-Mesothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	TBX15 ILDR2 NKX6-2 RYR2 PPM1L	1.91e-04	156	151	5	605d95a900e1443d3f6aae163ef2e893d3293203
ToppCell	E16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PDE7A CLIC3 CCDC141 HMCN2 BEND7	2.28e-04	162	151	5	34b4cd3d2258f88dfbd6d32abd1db87aff8a6b6f
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DUOX2 USP9Y SCN9A SCN10A WNK2	2.28e-04	162	151	5	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-CytoT_GZMK+-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	TPR NDST2 TTC7B ZNF30 IMPG2	2.28e-04	162	151	5	19395bdb282b4a2d88cd33191af12c24a88c3d16
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Cfh_(Cfh)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	AADAC FKBP6 COL6A6 BST1	2.28e-04	88	151	4	5582666aed9c1f465264f18898783872b662400d
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Cfh_(Cfh)--\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	AADAC FKBP6 COL6A6 BST1	2.28e-04	88	151	4	5f774a85415d3cf163046f1154a82f749bf628fe
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Cfh_(Cfh)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	AADAC FKBP6 COL6A6 BST1	2.28e-04	88	151	4	f59eeaba4a3c5ef03f741ed6a31fe88f57651374
ToppCell	Healthy_Control-Lymphoid-B-\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	CR2 PTPN7 HMCN2 CD19 ST6GALNAC5	2.35e-04	163	151	5	d84bd41b4494c7d5c7f88d511bfe481fb12f079d
ToppCell	Healthy_Control-Lymphoid-B\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	CR2 PTPN7 HMCN2 CD19 ST6GALNAC5	2.35e-04	163	151	5	0f723ec2503afa1b3ebb0754972438ffb6e6179d
ToppCell	10x5'-bone_marrow-Lymphocytic_B-ABC_aged-B_memory\|bone_marrow / Manually curated celltypes from each tissue	CNFN SYNPO CCDC141 PIKFYVE CD19	2.41e-04	164	151	5	746833f74095c0f25ce76baf1069f1848c231933
ToppCell	facs-Trachea-18m-Epithelial-glandular_epithelial-lung_secretory_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FKBP6 CLIC3 BEND7 VASH2 SLC4A5	2.41e-04	164	151	5	cdb8cd2d6b369189ea77e4946738e2816d502e03
ToppCell	E16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PDE7A CLIC3 NBEAL2 BEND7 SLC4A5	2.41e-04	164	151	5	fe11fcce4ba7f44ba2989ea3705916b67e75f8e7
ToppCell	B_cells-ABCs\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	CCDC141 PIKFYVE CD19 CDCA7 NBEAL2	2.41e-04	164	151	5	f45013706a917f0f0d69c23f288128f252cd60c7
ToppCell	facs-Trachea-18m-Epithelial-glandular_epithelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FKBP6 CLIC3 BEND7 VASH2 SLC4A5	2.41e-04	164	151	5	5dbfcdd450f652b16d97da53b528d4584b0eabcf
ToppCell	E16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PDE7A CLIC3 NBEAL2 BEND7 SLC4A5	2.41e-04	164	151	5	b6beb8548ac0dd07e8a580a938e5ee4bf25a3c1f
ToppCell	facs-Trachea-18m-Epithelial-glandular_epithelial-lung_secretory_cell-mucous\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FKBP6 CLIC3 BEND7 VASH2 SLC4A5	2.41e-04	164	151	5	f1423f4434af4af9c60c8a5b0b0abec4a7df9401
ToppCell	3'_v3-Lung-Lymphocytic_B-ABC_aged-B_memory\|Lung / Manually curated celltypes from each tissue	SYNPO ZNF768 CD19 CDCA7 HECW2	2.41e-04	164	151	5	7766900740f67dbbe3c4d90fbfdcc1665cee6515
ToppCell	Mild-Myeloid-Mast\|Mild / Condition, Lineage, Cell class and cell subclass	CTTNBP2 PPM1H SCN9A FERMT2 VWA5B1	2.48e-04	165	151	5	5fa9552c37890c5cc7e672a47038aebba2413cb4
ToppCell	Mild-Myeloid-Mast-\|Mild / Condition, Lineage, Cell class and cell subclass	CTTNBP2 PPM1H SCN9A FERMT2 VWA5B1	2.48e-04	165	151	5	93d3909a0f5f43d473d5005c842d7d73e25eceed
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ICOSLG CR2 USF3 CD19 CNN3	2.48e-04	165	151	5	fead3f2032f8fa5f7f0159a4434989b3d65debbb
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-TRGV2_gdT\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CLIC3 CBARP GNLY CCDC141 PPM1L	2.70e-04	168	151	5	2765d98f0b7f6861d662937535e051d41dba3500
ToppCell	facs-Lung-EPCAM-3m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE7A CR2 CD19 ST8SIA5 TEX44	2.70e-04	168	151	5	784ce773521e5d74570f45120e56d112bc76ff49
ToppCell	Control-Mast_cells\|Control / group, cell type (main and fine annotations)	CTTNBP2 NDST2 PPM1H MCTP1 TTC7B	2.77e-04	169	151	5	fdb9abca1d0f4fdc32dd8ac6231651ef34aa5afb
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ANKRD13D PIEZO1 IFIH1 BEND7 RAB11FIP3	2.77e-04	169	151	5	665b958f4a720ca369a8a0abc7fbe8b6e13c8ce5
ToppCell	Frontal_cortex-Neuronal-Inhibitory\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	KRT1 FNDC1 VASH2 SCN9A ELAVL2	2.77e-04	169	151	5	78eb70dd916724e476eabccf18fb7fcec4210308
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ANKRD13D PIEZO1 IFIH1 BEND7 RAB11FIP3	2.77e-04	169	151	5	6614c9851537e4c21b1e45ff0cc3bad07ef9d034
ToppCell	B_cell\|World / lung cells shred on cell class, cell subclass, sample id	PDE7A CR2 PTPN7 CD19 CDCA7	2.85e-04	170	151	5	cec4090ba6a9c934d5f6f9e4aa7823f3713319b7
ToppCell	Control-Myeloid-Mast\|Control / Disease state, Lineage and Cell class	KRT1 CTTNBP2 DUOX2 PPM1H FERMT2	2.85e-04	170	151	5	9a14deb7f7cd4a49c217eba4023f7bf1dec6c902
ToppCell	facs-Lung-EPCAM-3m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE7A CR2 CD19 ST8SIA5 TEX44	2.85e-04	170	151	5	7a4ed69c807c3761210776e8fe6680d1bd892e82
ToppCell	Control-Mast_cells-Mast_cells\|Control / group, cell type (main and fine annotations)	CTTNBP2 NDST2 PPM1H MCTP1 TTC7B	2.85e-04	170	151	5	c80f6d29096c372da95a8407f402349ff1bb7018
ToppCell	normal-na-Lymphocytic_NK-natural_killer_cell-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	MYT1L CLIC3 GNLY PPM1L HYAL2	2.93e-04	171	151	5	d339840626211a7bf1a9eb8f14d6c9509ab05e1c
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PEG10 SAV1 CR2 CD19 CNN3	3.01e-04	172	151	5	62ed3b70fa1f6c84ea80ff00f60d2562be292e9d
ToppCell	5'-Adult-Appendix-Hematopoietic-Myeloid-Mast_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KRT1 CTTNBP2 NDST2 PPM1H VWA5B1	3.09e-04	173	151	5	a7dee23b1d43d3070d502487af319ff81a9a747b
ToppCell	368C-Myeloid-Mast_cell\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	KRT1 ADGRB2 DUOX2 PPM1H PTPN7	3.09e-04	173	151	5	8cffb4a37d30b6626188309b868ac4a62e91262f
ToppCell	368C-Myeloid-Mast_cell-\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	KRT1 ADGRB2 DUOX2 PPM1H PTPN7	3.09e-04	173	151	5	fb87ea74bf70aa83b458edf728c81857c8b8eb96
ToppCell	10x5'-GI_small-bowel-Myeloid_Monocytic-Classical_monocytes\|GI_small-bowel / Manually curated celltypes from each tissue	DMXL2 OSCAR MCTP1 BST1 SYN1	3.17e-04	174	151	5	05d54a36772f096047521e16a89cc42ae48d2a1d
ToppCell	10x5'-GI_small-bowel-Mast\|GI_small-bowel / Manually curated celltypes from each tissue	KRT1 CTTNBP2 PPM1H MCTP1 MROH7	3.17e-04	174	151	5	e94c980b25edfd0e8598c416828801fcc00e8ead
ToppCell	10x5'-GI_small-bowel-Mast-Mast_cells\|GI_small-bowel / Manually curated celltypes from each tissue	KRT1 CTTNBP2 PPM1H MCTP1 MROH7	3.17e-04	174	151	5	05525bf0a2bde2be4f7c147b17a24530ce8819e0
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO1 CDCA7 HECW2 NAV3 HYAL2	3.25e-04	175	151	5	90302e8a44858ef3b2a165b88284d4788d591a99
ToppCell	5'-Adult-Distal_Rectal-Epithelial-goblet-BEST2+_Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PIEZO1 SLC28A3 CYP2W1 CDCA7 WNK2	3.25e-04	175	151	5	019ea30ac55748463d7917abf3d3f0e804189bfd
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-early_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SHC4 CD19 BST1 RPTOR CNN3	3.34e-04	176	151	5	29cda51a99100ddd2928cadc92da40f001d7e1f4
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-early_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SHC4 CD19 BST1 RPTOR CNN3	3.34e-04	176	151	5	01774a86d7d92f31a056b753f9844f923038003e
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HTR2A REV3L RYR2 TBX18 NAV3	3.43e-04	177	151	5	9ec7f1e64312d26d434b3312b58386715dbad644
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HTR2A REV3L RYR2 TBX18 NAV3	3.43e-04	177	151	5	016277dfd59b1793fddaaadc2b3f41622d76ce3a
ToppCell	COVID-19_Moderate-B_intermediate\|COVID-19_Moderate / disease group, cell group and cell class	CNFN SYNPO CCDC141 PIKFYVE CD19	3.43e-04	177	151	5	68e3d12a0c048a2d0f1b9680c7338a35855bba30
Disease	susceptibility to mononucleosis measurement	MYT1L TBX15 CUL1 RYR2 MDN1	2.41e-05	69	146	5	EFO_0008403
Disease	Primary Erythermalgia	SCN9A SCN10A	7.27e-05	3	146	2	C0014805
Disease	PAROXYSMAL EXTREME PAIN DISORDER	SCN9A SCN10A	7.27e-05	3	146	2	C1833661
Disease	Hypogammaglobulinemia	CR2 CD19 CDCA7	7.67e-05	17	146	3	C0086438
Disease	Idiopathic hypogonadotropic hypogonadism	CCDC141 FGF17 POLR3B	9.17e-05	18	146	3	C0342384
Disease	Glycogen phosphorylase kinase deficiency	PHKA1 PHKA2	1.45e-04	4	146	2	cv:C0268147
Disease	IMMUNODEFICIENCY, COMMON VARIABLE, 2	CR2 CD19	2.41e-04	5	146	2	240500
Disease	Immunodeficiency, common variable, 2	CR2 CD19	2.41e-04	5	146	2	cv:C3150354
Disease	smoking behavior	CTTNBP2 ADGRB2 SLC28A3 REV3L MCTP1 BEND7 NAV3 SDK1	3.10e-04	341	146	8	EFO_0004318
Disease	Congenital Pain Insensitivity	SCN9A SCN10A	5.02e-04	7	146	2	C0002768
Disease	Hereditary Sensory Autonomic Neuropathy, Type 5	SCN9A SCN10A	5.02e-04	7	146	2	C0020075
Disease	smoking status measurement	MYT1L CTTNBP2 PDE7A ADGRB2 SLC28A3 REV3L DCAF5 RYR2 ADD3 MCTP1 HECW2 BEND7 ELAVL2 DLEC1 SDK1	6.56e-04	1160	146	15	EFO_0006527
Disease	attention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement	CTTNBP2 PDE7A ADGRB2 GPR135 SLC28A3 REV3L RYR2 MCTP1 CDCA7 BEND7 ELAVL2 SDK1	6.59e-04	801	146	12	EFO_0003888, EFO_0007052, MONDO_0002491
Disease	sick sinus syndrome	CCDC141 SCN10A	6.68e-04	8	146	2	MONDO_0001823
Disease	familial sick sinus syndrome	CCDC141 SCN10A	6.68e-04	8	146	2	MONDO_0012061
Disease	eye morphology measurement	MYT1L TBX15 WWOX PHKA1 TBX18 NAV3	7.80e-04	218	146	6	EFO_0007858
Disease	Autism Spectrum Disorders	MYT1L CTTNBP2 RYR2 GLRA2	8.54e-04	85	146	4	C1510586
Disease	glycogen storage disease (is_implicated_in)	PHKA1 PHKA2	8.56e-04	9	146	2	DOID:2747 (is_implicated_in)
Disease	smoking behaviour measurement	CTTNBP2 ADGRB2 SLC28A3 REV3L BST1 SDK1	8.57e-04	222	146	6	EFO_0005671
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN9A SCN10A	1.07e-03	10	146	2	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN9A SCN10A	1.07e-03	10	146	2	DOID:0080422 (implicated_via_orthology)
Disease	HYPOGONADOTROPIC HYPOGONADISM 7 WITH OR WITHOUT ANOSMIA	CCDC141 FGF17	1.30e-03	11	146	2	146110
Disease	Hypogonadotropic hypogonadism 7 with or without anosmia	CCDC141 FGF17	1.30e-03	11	146	2	cv:C0342384
Disease	Immunoglobulin Deficiency, Late-Onset	CR2 CD19	1.30e-03	11	146	2	C2936665
Disease	Acquired Hypogammaglobulinemia	CR2 CD19	1.30e-03	11	146	2	C2936664
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN9A SCN10A	1.55e-03	12	146	2	DOID:0060170 (implicated_via_orthology)
Disease	spontaneous preterm birth	MYT1L SLC28A3 DLEC1 SDK1	1.62e-03	101	146	4	EFO_0006917
Disease	Common variable immunodeficiency	CR2 CD19	1.83e-03	13	146	2	cv:C0009447
Disease	hypothyroidism (implicated_via_orthology)	DUOX2 PHKA1	1.83e-03	13	146	2	DOID:1459 (implicated_via_orthology)
Disease	hair morphology measurement	WWOX MCTP1 RPTOR	2.45e-03	54	146	3	EFO_0007821
Disease	Common Variable Immunodeficiency	CR2 CD19	2.45e-03	15	146	2	C0009447
Disease	anemia (implicated_via_orthology)	SLC4A2 SLC4A5	2.45e-03	15	146	2	DOID:2355 (implicated_via_orthology)
Disease	R-6-hydroxywarfarin measurement	WWOX SLC28A3 NCOR2 TRAPPC9	2.52e-03	114	146	4	EFO_0803327
Disease	Neuralgia, Supraorbital	SCN9A SCN10A	2.79e-03	16	146	2	C0038870
Disease	Neuralgia	SCN9A SCN10A	2.79e-03	16	146	2	C0027796
Disease	Neuralgia, Atypical	SCN9A SCN10A	2.79e-03	16	146	2	C0234247
Disease	Neuralgia, Stump	SCN9A SCN10A	2.79e-03	16	146	2	C0234249
Disease	Neuralgia, Iliohypogastric Nerve	SCN9A SCN10A	2.79e-03	16	146	2	C0423712
Disease	Neuralgia, Perineal	SCN9A SCN10A	2.79e-03	16	146	2	C0423711
Disease	Paroxysmal Nerve Pain	SCN9A SCN10A	2.79e-03	16	146	2	C0751373
Disease	Nerve Pain	SCN9A SCN10A	2.79e-03	16	146	2	C0751372
Disease	Neuralgia, Ilioinguinal	SCN9A SCN10A	2.79e-03	16	146	2	C0751371
Disease	Neuralgia, Vidian	SCN9A SCN10A	2.79e-03	16	146	2	C0042656
Disease	Glycogen storage disease	PHKA1 PHKA2	3.15e-03	17	146	2	cv:C0017919
Disease	Cannabis use, age at onset	SLC28A3 RYR2	3.93e-03	19	146	2	EFO_0004847, EFO_0007585
Disease	Epstein-Barr virus infection	WWOX SLC6A5 DLEC1	4.32e-03	66	146	3	EFO_0000769

Protein segments in the cluster

Peptide	Gene	Start	Entry
VYRGMELLRSARTQS	UMODL1	346	Q5DID0
GTATLLIVRYQRMNG	UMODL1	1286	Q5DID0
GSEGDYMVLPRRTLS	ADGRB2	1346	O60241
RRLLQMDSGYASIEG	CBARP	496	Q8N350
DNTRRFMPLSDVLYG	BST1	121	Q10588
RSYNLQERRRIGSMT	SLC4A2	231	P04920
PMYTGRERVNREGSL	CEACAM18	86	A8MTB9
NGYSVLGMERNEPLR	ANKRD13D	466	Q6ZTN6
RNMGYLNSSPLSRRA	CFAP97	466	Q9P2B7
NRREREAMILSSYAG	C2orf80	81	Q0P641
ERRTYLAEMSQGSGL	CCDC169	146	A6NNP5
RDDGLMYVTRLRNTG	AADAC	346	P22760
FEGLMRTLDNLGYRT	ADD3	371	Q9UEY8
PAELRGVRRYLDSAM	CLIC3	196	O95833
LRPDRELSNRSVYGM	A2ML1	601	A8K2U0
REPGSYTGRRTMQSI	HTR2A	301	P28223
QQDRSLMELSERYGP	CYP2W1	51	Q8TAV3
TGMAYQGLLLSDRRR	DMXL2	2286	Q8TDJ6
RRREPGGYDSSSTLM	DVL3	166	Q92997
GAMTDQLSRRQIREY	FGF17	41	O60258
RRIPEEYSLGRMAEG	MROH7	996	Q68CQ1
QRRGRSSSMGLQEYH	RAB11FIP3	641	O75154
MGTRRAYLGVAALND	IPP	471	Q9Y573
RYNRSDIMPSGRSRL	PUM2	696	Q8TB72
LRLDRGGMIQTAEQY	PTPN7	326	P35236
EVMLLETSRRYNPGS	NR1H3	296	Q13133
DQMLSYNLGRRLPAD	HECW2	296	Q9P2P5
LLYRDGEQTEPSRMG	NCOR2	2241	Q9Y618
RMHRVGELSGDNYLR	IL17RA	546	Q96F46
PTYSRRLTGLSEMDL	HYAL2	296	Q12891
RAMRNRGLEIYISGE	MDN1	2301	Q9NU22
AYQLGLDESREMTRG	LIN52	91	Q52LA3
ADPGMYQLDITLRRG	MCTP1	256	Q6DN14
EYNMSGIILRRNGDL	MOV10L1	551	Q9BXT6
NAMRYINGTRLDDRI	NCBP2	96	P52298
RRYGLLANTEDPTEM	FAM174C	101	Q9BVV8
LQLGRARLSDSGMYT	HMCN2	3001	Q8NDA2
KSPYGRRQGDLMESL	CHUK	546	O15111
MRSRSNSGVRLDGYA	PHKA1	1	P46020
YSMQGEEARAALLRP	ATXN1L	656	P0C7T5
QRGRDMGLPSYSQAL	DUOX2	431	Q9NRD8
TYRTLLEGEESRMSG	KRT1	481	P04264
SDQTALYIRMLGDVR	PDE7A	56	Q13946
MTDGGLNLYTRSLNR	NAV3	841	Q8IVL0
MRRYQSRVTQGLVAG	GNLY	111	P22749
RYGGNLSLQSAMSVR	DCAF5	226	Q96JK2
GLRGTEEMTRRYNIN	DNAJC16	306	Q9Y2G8
IRRLRQGMGSVIDYS	PEG10	171	Q86TG7
SRLYDAVLRGPMDSD	NAXD	211	Q8IW45
RRNRVLAGLYMGRSD	GCN1	1881	Q92616
TYDRRLSDDQGMPKT	MAGEA13P	181	A6NCF6
YGTLTDDEMRRLNIP	METTL3	406	Q86U44
AGRLRNMSFVLYREG	OSCAR	151	Q8IYS5
VDSRYRNRALMSPAG	ICOSLG	76	O75144
RFNMELYRLSGRRSG	NTN3	321	O00634
LYERLSQRMLDISGD	FKBP6	21	O75344
QSLGRMLADYRARGG	PIKFYVE	1146	Q9Y2I7
SRVSTLGLYMEANRQ	EIF2B3	311	Q9NR50
QDMRGRYEASQDLLG	CROCC	536	Q5TZA2
MLLGRNREEGYRTRN	GPR135	396	Q8IZ08
SGTSRGYQRQMVPRE	CCDC141	1376	Q6ZP82
ILRGRMVSGQKDRYT	CR2	356	P20023
SYGMSGREQLNRNLI	SDR42E1	81	Q8WUS8
EDMRGILYAAPQLRS	CD19	501	P15391
MARPGIDRQASYGDL	CTTNBP2	351	Q8WZ74
RMYNLVSRIQDGLGE	CUL1	321	Q13616
SGRKMNYVPLTRDER	FNDC1	201	Q4ZHG4
EALRRTGSPLAARYM	IFIH1	81	Q9BYX4
AMAIASLNGYRLGDR	ELAVL2	331	Q12926
RGQERLSSSMIPGYT	FAM166B	81	A8MTA8
LMGRTSGYDARIRPN	GLRA2	51	P23416
IDRDSYRRILMGSTL	PRKAR1A	226	P10644
EITTRYRNTMSNGGL	KLB	21	Q86Z14
IDRDSYRRILMGSTL	PRKAR1B	226	P31321
GMRRLLNDSTGRIYQ	BEND7	61	Q8N7W2
ELLRQLARGGTMVTY	MECR	271	Q9BV79
EAPGRSMRVATGLYE	CCDC177	121	Q9NQR7
VLGSRRMPYESETNQ	ENAM	521	Q9NRM1
IGIAYNRLIRMDAST	FERMT2	586	Q96AC1
MRGRYEASQDLLGTL	CROCCP3	1	Q8IVE0
TLRLRGQGSYDERYM	DLEC1	1736	Q9Y238
EVTELRRLTGSYNTM	SAMM50	121	Q9Y512
RGQYSAETSRLMLPE	SDK1	751	Q7Z5N4
GLRTQDLSYFRDMPR	SPACA6	191	W5XKT8
RTREGDSMALYNRTR	RYR2	2791	Q92736
YRTQLSIGMRELGSR	COL6A6	1356	A6NMZ7
YGEAARMDSRRTLPA	FTCD	126	O95954
MRSRSNSGVRLDGYA	PHKA2	1	P46019
LRRISAARYGEVGMS	TMEM67	206	Q5HYA8
MATNRGITRIRGTSY	RUVBL2	326	Q9Y230
SMARNGDYRSLVIGL	SYN1	191	P17600
LPNADMETRRGAYLN	USP9X	1136	Q93008
ETARRRAMLDSGIYP	SNAPIN	116	O95295
RGERYKNMIDPLGTS	SLC6A5	766	Q9Y345
PERARLAYSLGMTES	NKX6-2	176	Q9C056
GPERARLAYSLGMTE	NKX6-3	166	A6NJ46
GMTLPYDTLDQVRNR	NDUFS1	631	P28331
SGKGAELYARRQSRM	SYNPO	721	Q8N3V7
SQGYLSSRSPQEMLR	NBEAL2	2046	Q6ZNJ1
GRNRTGLEAIMETYA	TBX15	306	Q96SF7
RVQGILAMSRSLGDY	PPM1L	256	Q5SGD2
EYTSIRRSRIMGLSE	SCN9A	446	Q15858
RRYLLTGQANGSLAM	SHKBP1	561	Q8TBC3
MRYADPSANRDLLGS	ST8SIA5	1	O15466
IRMNDAPTRGYGRDV	ST6GALNAC5	121	Q9BVH7
MELRSTAAPRAEGYS	SLC28A3	1	Q9HAS3
GMYSEPLRQFRDSSV	STARD9	3106	Q9P2P6
IGGLSREEIRQMYES	IMPG2	1191	Q9BZV3
GDGSIRVYDRRMALS	RPTOR	1186	Q8N122
MDGYRRILNLLSPSD	GTF3C3	271	Q9Y5Q9
GYMNEDDLPRSRRSR	CDCA7	216	Q9BWT1
SIRTGMRERYHIQGS	CNFN	71	Q9BYD5
KMGNRRTANIRSLGY	CNGA2	531	Q16280
QAGMLAPGTRRDIYD	CNN3	216	Q15417
MRERGQDSLAGLVLY	SHC4	1	Q6S5L8
RGPELKQASRRDMYT	SUPT6H	511	Q7KZ85
QRTVEGIRSAMRYLT	TEX44	366	Q53QW1
MRRESNRLSAPSYLA	SAV1	86	Q9H4B6
LDSSQRGLYRDVMLE	ZNF30	31	P17039
RSYSQEGSRERAQGM	TEX13D	596	A0A0J9YY54
VAMVNLGRLYRSLGE	TMTC1	651	Q8IUR5
LGRLYRSLGENSMAE	TMTC1	656	Q8IUR5
LESDGYRGERNRMPS	REV3L	421	O60673
RYTLAAQDLVMRARG	PPM1H	466	Q9ULR3
TPLDYNRRGTSLMED	STAG2	1151	Q8N3U4
RDMYRILLSQTTGVA	TPR	611	P12270
RRMRGRYNNTISELS	ILDR2	326	Q71H61
SGRNRMGLEALVESY	TBX18	331	O95935
YESVTRGLSDRVNMR	SCN10A	1921	Q9Y5Y9
NGMELDGRRIRVDYS	TRA2A	181	Q13595
SDYPMTDGQLRSKRD	UBTD2	41	Q8WUN7
QSSDEMRSPEGYLRG	ZNF768	16	Q9H5H4
SKGRRYPDMDTESRL	NDST2	831	P52849
MENRALDPGTRDSYG	PHF19	1	Q5T6S3
RYDGSTTAMEILQGR	WWOX	106	Q9NZC7
TEDLRMRQSANYGRL	SLC4A5	256	Q9BY07
GGPSDIIYADLRRMN	SH2D7	236	A6NKC9
NGRYGSLGMSRRAEL	VASH2	201	Q86V25
MDRQGVTQVLSRLSY	POLR3B	431	Q9NW08
GSRVSDQLEMRSYLD	USF3	1691	Q68DE3
FLPNTDMETRRGAYL	USP9Y	1136	O00507
QDRISRLMGDYLLRG	ZNRD2	31	O60232
NVLYMRGQIAELRGS	TTC7B	731	Q86TV6
ELVYASRRMGNPALS	TRAPPC9	466	Q96Q05
REAGASLYQGLMRTA	PIEZO1	1631	Q92508
SPRSMLGYDRDGRQV	WNK2	1686	Q9Y3S1
VEYPNSAALRMLGSR	VWA5B1	916	Q5TIE3
DMTLARNTYGRLNSG	ZNF324B	66	Q6AW86
LRPGFMEDRGRENYS	ZNF326	141	Q5BKZ1
RALYRSGMREALSQE	KLHL42	31	Q9P2K6
YRQLLEGEESRMSGE	KRT77	466	Q7Z794
TGMLETVRIRRSGYS	MYO9B	876	Q13459
RQYLGGRDSLMSQAP	PDE4DIP	681	Q5VU43
AGRRDNMRSYEDQSP	MYT1L	456	Q9UL68