Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionactive transmembrane transporter activity

ABCG1 SLC12A1 CLCN4 SLC12A3 SLC35E2A SLC6A17 SLC5A6 UCP2 ABCB8 SLC28A1 SLC17A7 SLC35E2B ABCG5 SLC29A4 SLC12A5

2.43e-094778815GO:0022804
GeneOntologyMolecularFunctiontransmembrane transporter activity

ABCG1 SLC25A20 PIEZO2 SLC12A1 CLCN4 SLC12A3 RHBG SLC35E2A SLC6A17 SLC5A6 UCP2 ABCB8 SLC28A1 SLC17A7 GRIN2B SLC35E2B ABCG5 SLC29A4 RHAG MFSD3 SLC12A5

2.96e-0811808821GO:0022857
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC12A1 CLCN4 SLC12A3 SLC35E2A SLC6A17 SLC5A6 UCP2 SLC28A1 SLC17A7 SLC35E2B SLC12A5

7.34e-082968811GO:0015291
GeneOntologyMolecularFunctiontransporter activity

ABCG1 SLC25A20 PIEZO2 SLC12A1 CLCN4 SLC12A3 RHBG SLC35E2A SLC6A17 SLC5A6 UCP2 ABCB8 SLC28A1 SLC17A7 GRIN2B SLC35E2B ABCG5 SLC29A4 RHAG MFSD3 SLC12A5

1.33e-0712898821GO:0005215
GeneOntologyMolecularFunctionsymporter activity

SLC12A1 SLC12A3 SLC6A17 SLC5A6 SLC28A1 SLC17A7 SLC12A5

4.48e-06150887GO:0015293
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

SLC12A1 CLCN4 SLC12A3 SLC5A6 UCP2 SLC17A7 SLC12A5

4.68e-06151887GO:0008509
GeneOntologyMolecularFunctionpotassium:chloride symporter activity

SLC12A1 SLC12A3 SLC12A5

6.82e-069883GO:0015379
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

SLC12A1 CLCN4 SLC12A3 SLC5A6 UCP2 SLC17A7 SLC12A5

1.06e-05171887GO:0015103
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC12A1 SLC12A3 SLC5A6 SLC28A1 SLC17A7 SLC12A5

1.44e-05119886GO:0015294
GeneOntologyMolecularFunctionammonium channel activity

RHBG RHAG SLC12A5

1.77e-0512883GO:0008519
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

SLC12A1 CLCN4 SLC12A3 UCP2 SLC17A7 SLC12A5

1.90e-05125886GO:0015108
GeneOntologyMolecularFunctionphosphate ion uniporter activity

UCP2 SLC17A7

1.92e-052882GO:0140787
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC12A1 SLC12A3 SLC5A6 SLC28A1 SLC17A7

2.92e-0581885GO:0015370
GeneOntologyMolecularFunctionsodium:potassium:chloride symporter activity

SLC12A1 SLC12A3

5.74e-053882GO:0008511
GeneOntologyMolecularFunctionpotassium:sodium symporter activity

SLC12A1 SLC12A3

5.74e-053882GO:0009674
GeneOntologyMolecularFunctioncarbon dioxide transmembrane transporter activity

RHBG RHAG

1.15e-044882GO:0035379
GeneOntologyMolecularFunctionchloride:monoatomic cation symporter activity

SLC12A1 SLC12A3 SLC12A5

1.37e-0423883GO:0015377
GeneOntologyMolecularFunctionbeta-catenin binding

CARM1 CSNK2A1 GRIN2B MED12 CDH13

1.90e-04120885GO:0008013
GeneOntologyMolecularFunctionmembrane potential driven uniporter activity

UCP2 SLC17A7

1.90e-045882GO:0022810
GeneOntologyMolecularFunctionmonoatomic anion:monoatomic cation symporter activity

SLC12A1 SLC12A3 SLC12A5

2.00e-0426883GO:0015296
GeneOntologyMolecularFunctionpoly(A) binding

PABPC3 ELAVL4 PABPC1

2.78e-0429883GO:0008143
GeneOntologyMolecularFunctionantiporter activity

CLCN4 SLC35E2A UCP2 SLC17A7 SLC35E2B

3.63e-04138885GO:0015297
GeneOntologyMolecularFunctionextracellularly glutamate-gated ion channel activity

SLC17A7 GRIN2B

3.97e-047882GO:0005234
GeneOntologyMolecularFunctioncytochrome-b5 reductase activity, acting on NAD(P)H

CYB5R3 CYB5R2

3.97e-047882GO:0004128
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC12A1 SLC12A3 RHBG SLC5A6 UCP2 SLC28A1 SLC17A7 GRIN2B RHAG SLC12A5

4.33e-046278810GO:0022890
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC12A1 CLCN4 SLC12A3 RHBG SLC5A6 UCP2 SLC28A1 SLC17A7 GRIN2B RHAG SLC12A5

4.90e-047588811GO:0015318
GeneOntologyMolecularFunctionpoly-purine tract binding

PABPC3 ELAVL4 PABPC1

5.77e-0437883GO:0070717
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

PIEZO2 SLC12A1 SLC12A3 SLC5A6 UCP2 SLC28A1 SLC17A7 GRIN2B SLC29A4 SLC12A5

6.75e-046648810GO:0008324
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

PIEZO2 SLC12A1 CLCN4 SLC12A3 SLC5A6 UCP2 SLC28A1 SLC17A7 GRIN2B SLC29A4 SLC12A5

7.13e-047938811GO:0015075
GeneOntologyMolecularFunctionnucleoside transmembrane transporter activity

SLC28A1 SLC29A4

8.44e-0410882GO:0005337
GeneOntologyMolecularFunctionuniporter activity

UCP2 SLC17A7

8.44e-0410882GO:0015292
GeneOntologyMolecularFunctionchromatin DNA binding

SOX2 TOX4 TOX3 RUNX2 CREBBP

8.63e-04167885GO:0031490
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC12A1 SLC12A3 SLC5A6 SLC28A1 SLC17A7

9.59e-04171885GO:0015081
GeneOntologyMolecularFunctionFAD binding

CYB5R3 MICAL3 CYB5R2

9.61e-0444883GO:0071949
GeneOntologyMolecularFunctionDNA-binding transcription factor binding

SOX2 CARM1 GBX2 TAF4 RUNX2 RUNX1 FOXA1 CREBBP MED12

1.05e-03582889GO:0140297
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H, heme protein as acceptor

CYB5R3 CYB5R2

1.23e-0312882GO:0016653
GeneOntologyMolecularFunctiontoxin transmembrane transporter activity

ABCG1 SLC29A4

1.23e-0312882GO:0019534
GeneOntologyMolecularFunctionarginine N-methyltransferase activity

CARM1 PRMT7

1.23e-0312882GO:0016273
GeneOntologyMolecularFunctionprotein-arginine N-methyltransferase activity

CARM1 PRMT7

1.23e-0312882GO:0016274
GeneOntologyMolecularFunctionABC-type transporter activity

ABCG1 ABCB8 ABCG5

1.32e-0349883GO:0140359
GeneOntologyMolecularFunctionchromatin binding

SOX2 TOX4 TOX3 SREBF2 RUNX2 RUNX1 FOXA1 CREBBP MED12 CBX2

1.52e-037398810GO:0003682
GeneOntologyMolecularFunctiontranscription factor binding

SOX2 CARM1 ATF7 GBX2 TAF4 RUNX2 RUNX1 FOXA1 CREBBP MED12

1.74e-037538810GO:0008134
GeneOntologyMolecularFunctiontranscription coactivator binding

ATF7 RUNX1 CREBBP

1.74e-0354883GO:0001223
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC12A1 SLC12A3 SLC5A6 SLC28A1 SLC17A7 SLC12A5

2.15e-03301886GO:0022853
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC5A6 UCP2 SLC17A7 GRIN2B SLC29A4

2.27e-03208885GO:0005342
GeneOntologyMolecularFunctionnuclear receptor coactivator activity

CARM1 ZMIZ2 MED12

2.48e-0361883GO:0030374
GeneOntologyMolecularFunctionsodium:chloride symporter activity

SLC12A1 SLC12A3

2.50e-0317882GO:0015378
GeneOntologyMolecularFunctionmonoatomic anion:sodium symporter activity

SLC12A1 SLC12A3

3.13e-0319882GO:0015373
GeneOntologyMolecularFunctionacidic amino acid transmembrane transporter activity

UCP2 SLC17A7

3.46e-0320882GO:0015172
GeneOntologyMolecularFunctionneurotransmitter transmembrane transporter activity

SLC17A7 SLC29A4

3.82e-0321882GO:0005326
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC12A1 SLC12A3 SLC5A6 SLC28A1 SLC17A7 GRIN2B SLC12A5

4.46e-03465887GO:0046873
GeneOntologyMolecularFunctionankyrin binding

RHBG RHAG

4.57e-0323882GO:0030506
GeneOntologyMolecularFunctionphosphate transmembrane transporter activity

UCP2 SLC17A7

4.98e-0324882GO:0005315
GeneOntologyMolecularFunctioncholesterol transfer activity

ABCG1 ABCG5

4.98e-0324882GO:0120020
GeneOntologyMolecularFunctionsterol transfer activity

ABCG1 ABCG5

5.39e-0325882GO:0120015
GeneOntologyMolecularFunctionorganic cation transmembrane transporter activity

SLC25A20 SLC29A4 RHAG

5.89e-0383883GO:0015101
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

SLC12A1 SLC12A3 SLC17A7 SLC12A5

6.38e-03167884GO:0015079
GeneOntologyMolecularFunctionflavin adenine dinucleotide binding

CYB5R3 MICAL3 CYB5R2

8.31e-0394883GO:0050660
GeneOntologyMolecularFunctionchannel activity

PIEZO2 CLCN4 RHBG SLC17A7 GRIN2B RHAG SLC12A5

8.48e-03525887GO:0015267
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H

CYB5R3 NNT CYB5R2

8.55e-0395883GO:0016651
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

PIEZO2 CLCN4 RHBG SLC17A7 GRIN2B RHAG SLC12A5

8.57e-03526887GO:0022803
GeneOntologyBiologicalProcessinorganic anion transmembrane transport

SLC12A1 CLCN4 SLC12A3 SLC5A6 UCP2 SLC17A7 SLC12A5

1.46e-06134867GO:0098661
GeneOntologyBiologicalProcessmonoatomic anion transmembrane transport

SLC12A1 CLCN4 SLC12A3 SLC5A6 UCP2 SLC17A7 SLC12A5

3.54e-06153867GO:0098656
GeneOntologyBiologicalProcesschloride transmembrane transport

SLC12A1 CLCN4 SLC12A3 UCP2 SLC17A7 SLC12A5

7.40e-06112866GO:1902476
GeneOntologyBiologicalProcessinorganic anion transport

SLC12A1 CLCN4 SLC12A3 SLC5A6 UCP2 SLC17A7 SLC12A5

1.03e-05180867GO:0015698
GeneOntologyBiologicalProcessmonoatomic anion transport

SLC12A1 CLCN4 SLC12A3 SLC5A6 UCP2 SLC17A7 SLC12A5

1.15e-05183867GO:0006820
GeneOntologyBiologicalProcesschloride transport

SLC12A1 CLCN4 SLC12A3 UCP2 SLC17A7 SLC12A5

1.59e-05128866GO:0006821
GeneOntologyBiologicalProcessammonium transmembrane transport

RHBG RHAG SLC12A5

1.94e-0513863GO:0072488
GeneOntologyBiologicalProcesscell volume homeostasis

SLC12A1 SLC12A3 ABCB8 SLC12A5

2.79e-0542864GO:0006884
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

SOX2 CARM1 ATF7 ZNF827 ZMIZ2 TOX3 SREBF2 GBX2 TAF4 RUNX2 CAMTA1 RUNX1 FOXA1 RFX2 CREBBP MED12 CDH13

5.16e-0513908617GO:0045944
GeneOntologyBiologicalProcessorganic acid transmembrane transport

SLC25A20 SLC5A6 UCP2 AGT SLC17A7 SLC29A4

7.09e-05167866GO:1903825
GeneOntologyBiologicalProcesscarbon dioxide transmembrane transport

RHBG RHAG

1.03e-044862GO:0035378
GeneOntologyBiologicalProcesschloride ion homeostasis

SLC12A1 SLC12A3 SLC12A5

1.51e-0425863GO:0055064
GeneOntologyBiologicalProcesschemical homeostasis

ABCG1 SLC12A1 SLC12A3 RHBG UCP2 AGT NAGLU SREBF2 SLC17A7 GRIN2B FOXA1 NNT ABCG5 RHAG SLC12A5

1.86e-0412498615GO:0048878
GeneOntologyBiologicalProcesscellular homeostasis

ABCG1 SLC12A1 PLAA SLC12A3 UCP2 AGT ABCB8 NAGLU SLC17A7 GRIN2B NNT RHAG SLC12A5

2.04e-049818613GO:0019725
GeneOntologyBiologicalProcessmonoatomic anion homeostasis

SLC12A1 SLC12A3 SLC12A5

2.13e-0428863GO:0055081
GeneOntologyBiologicalProcesssterol biosynthetic process

ABCG1 CYB5R3 SREBF2 CYB5R2

2.33e-0472864GO:0016126
GeneOntologyBiologicalProcessammonium homeostasis

RHBG RHAG

2.55e-046862GO:0097272
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SLC12A1 CLCN4 SLC12A3 RHBG SLC6A17 SLC5A6 UCP2 ABCB8 SLC17A7 GRIN2B NNT RHAG SLC12A5

2.89e-0410178613GO:0098660
GeneOntologyBiologicalProcessorganic anion transport

SLC25A20 SLC6A17 SLC5A6 UCP2 AGT SLC17A7 GRIN2B CYB5R2 RHAG

2.94e-04515869GO:0015711
GeneOntologyBiologicalProcessorganic acid transport

SLC25A20 SLC6A17 SLC5A6 UCP2 AGT SLC17A7 GRIN2B SLC29A4

3.23e-04412868GO:0015849
GeneOntologyBiologicalProcessone-carbon compound transport

SLC12A1 RHBG RHAG

3.49e-0433863GO:0019755
GeneOntologyBiologicalProcessorganic cation transport

SLC25A20 SLC6A17 AGT SLC29A4 RHAG

3.53e-04145865GO:0015695
GeneOntologyBiologicalProcessimport across plasma membrane

SLC12A1 SLC12A3 SLC5A6 AGT SLC28A1 SLC12A5

4.03e-04230866GO:0098739
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

SLC12A1 SLC12A3 RHBG SLC6A17 SLC5A6 UCP2 ABCB8 SLC17A7 GRIN2B NNT RHAG SLC12A5

4.30e-049228612GO:0098662
GeneOntologyBiologicalProcesspeptidyl-arginine methylation, to asymmetrical-dimethyl arginine

CARM1 PRMT7

4.73e-048862GO:0019919
GeneOntologyBiologicalProcessnucleoside transmembrane transport

SLC28A1 SLC29A4

4.73e-048862GO:1901642
GeneOntologyBiologicalProcesspotassium ion homeostasis

SLC12A1 SLC12A3 SLC12A5

4.91e-0437863GO:0055075
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

PIEZO2 SLC12A1 SLC12A3 SLC6A17 SLC5A6 UCP2 ABCB8 SLC17A7 GRIN2B NNT SLC29A4 SLC12A5

5.21e-049428612GO:0098655
GeneOntologyCellularComponentmCRD-mediated mRNA stability complex

PABPC3 PABPC1

2.54e-046872GO:0106002
GeneOntologyCellularComponentATP-binding cassette (ABC) transporter complex

ABCB8 ABCG5

2.54e-046872GO:0043190
DomainSLC12A_fam

SLC12A1 SLC12A3 SLC12A5

3.26e-067863IPR004842
DomainSLC12_C

SLC12A1 SLC12A3 SLC12A5

5.19e-068863IPR018491
DomainSLC12

SLC12A1 SLC12A3 SLC12A5

5.19e-068863PF03522
DomainRunt

RUNX2 RUNX1

6.27e-053862PF00853
DomainRunt_dom

RUNX2 RUNX1

6.27e-053862IPR013524
DomainAA_permease_N

SLC12A1 SLC12A3

6.27e-053862IPR013612
DomainRunxI_C_dom

RUNX2 RUNX1

6.27e-053862IPR013711
DomainRUNT

RUNX2 RUNX1

6.27e-053862PS51062
DomainRunx_central_dom

RUNX2 RUNX1

6.27e-053862IPR027384
Domain-

RUNX2 RUNX1

6.27e-0538624.10.770.10
DomainTF_Runt-rel_RUNX

RUNX2 RUNX1

6.27e-053862IPR016554
DomainAA_permease_N

SLC12A1 SLC12A3

6.27e-053862PF08403
DomainRunxI

RUNX2 RUNX1

6.27e-053862PF08504
DomainAML1_Runt

RUNX2 RUNX1

6.27e-053862IPR000040
DomainAA-permease/SLC12A_dom

SLC12A1 SLC12A3 SLC12A5

1.36e-0422863IPR004841
DomainAA_permease

SLC12A1 SLC12A3 SLC12A5

1.36e-0422863PF00324
DomainFAD_binding_6

CYB5R3 CYB5R2

2.08e-045862PF00970
DomainABC_2_trans

ABCG1 ABCG5

2.08e-045862IPR013525
DomainPolyA

PABPC3 PABPC1

2.08e-045862SM00517
DomainNADH-Cyt_B5_reductase

CYB5R3 CYB5R2

2.08e-045862IPR001834
DomainOxRdtase_FAD-bd_dom

CYB5R3 CYB5R2

2.08e-045862IPR008333
Domain-

PABPC3 PABPC1

2.08e-0458621.10.1900.10
DomainPABP

PABPC3 PABPC1

2.08e-045862PF00658
DomainAmmonium_transpt

RHBG RHAG

2.08e-045862IPR001905
DomainPABC

PABPC3 PABPC1

2.08e-045862PS51309
DomainAmmonium_transp

RHBG RHAG

2.08e-045862PF00909
DomainPABP_1234

PABPC3 PABPC1

2.08e-045862IPR006515
DomainNH4_transpt_AmtB-like_dom

RHBG RHAG

2.08e-045862IPR024041
DomainPABP_HYD

PABPC3 PABPC1

2.08e-045862IPR002004
DomainRhesusRHD

RHBG RHAG

2.08e-045862IPR002229
DomainABC2_membrane

ABCG1 ABCG5

2.08e-045862PF01061
Domainp53/RUNT-type_TF_DNA-bd

RUNX2 RUNX1

3.11e-046862IPR012346
Domain-

RUNX2 RUNX1

3.11e-0468622.60.40.720
Domain-

RHBG RHAG

4.34e-0478621.10.3430.10
DomainAmmonium/urea_transptr

RHBG RHAG

4.34e-047862IPR029020
DomainSAM_MT_PRMT

CARM1 PRMT7

7.39e-049862PS51678
DomainArg_MeTrfase

CARM1 PRMT7

7.39e-049862IPR025799
DomainSugar_P_trans_dom

SLC35E2A SLC35E2B

9.21e-0410862IPR004853
DomainFlavoprot_Pyr_Nucl_cyt_Rdtase

CYB5R3 CYB5R2

9.21e-0410862IPR001709
DomainTPT

SLC35E2A SLC35E2B

9.21e-0410862PF03151
DomainOxRdtase_FAD/NAD-bd

CYB5R3 CYB5R2

1.34e-0312862IPR001433
DomainNAD_binding_1

CYB5R3 CYB5R2

1.34e-0312862PF00175
DomainABC_tran

ABCG1 ABCB8 ABCG5

1.40e-0348863PF00005
DomainABC_TRANSPORTER_2

ABCG1 ABCB8 ABCG5

1.40e-0348863PS50893
DomainABC_TRANSPORTER_1

ABCG1 ABCB8 ABCG5

1.49e-0349863PS00211
DomainABC_transporter-like

ABCG1 ABCB8 ABCG5

1.58e-0350863IPR003439
DomainSEA

MUC16 MUC3A

1.84e-0314862SM00200
DomainHMG_box

SOX2 TOX4 TOX3

1.87e-0353863PF00505
DomainHMG_BOX_2

SOX2 TOX4 TOX3

1.97e-0354863PS50118
DomainHMG

SOX2 TOX4 TOX3

1.97e-0354863SM00398
Domain-

SOX2 TOX4 TOX3

2.08e-03558631.10.30.10
DomainHMG_box_dom

SOX2 TOX4 TOX3

3.35e-0365863IPR009071
DomainFd_Rdtase_FAD-bd

CYB5R3 CYB5R2

3.41e-0319862IPR017927
DomainFAD_FR

CYB5R3 CYB5R2

3.41e-0319862PS51384
DomainRiboflavin_synthase-like_b-brl

CYB5R3 CYB5R2

3.41e-0319862IPR017938
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC12A1 SLC12A3 RHBG SLC5A6 SLC28A1 SLC17A7 RUNX1 SLC29A4 RHAG SLC12A5

2.92e-072496810M5988
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ABCG1 SLC12A1 CLCN4 SLC12A3 RHBG SLC5A6 ABCB8 SLC28A1 SLC17A7 RUNX1 ABCG5 SLC29A4 CYB5R2 RHAG SLC12A5

1.68e-067366815M27287
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC12A1 SLC12A3 RHBG SLC5A6 SLC28A1 SLC17A7 SLC29A4 RHAG SLC12A5

1.98e-06238689MM15076
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ABCG1 SLC12A1 CLCN4 SLC12A3 RHBG SLC5A6 ABCB8 SLC28A1 SLC17A7 ABCG5 SLC29A4 CYB5R2 RHAG SLC12A5

3.60e-066816814MM14985
PathwayREACTOME_CATION_COUPLED_CHLORIDE_COTRANSPORTERS

SLC12A1 SLC12A3 SLC12A5

3.71e-067683M27339
PathwayREACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_MYELOID_CELLS

RUNX2 RUNX1 CREBBP

3.71e-067683M27799
PathwayREACTOME_CATION_COUPLED_CHLORIDE_COTRANSPORTERS

SLC12A1 SLC12A3 SLC12A5

3.71e-067683MM15081
PathwayREACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PPARALPHA

CARM1 AGT SREBF2 CHD9 CREBBP MED12

2.17e-05118686M27316
PathwayREACTOME_ACTIVATION_OF_GENE_EXPRESSION_BY_SREBF_SREBP

CARM1 SREBF2 CHD9 CREBBP

4.83e-0542684M27172
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION

CARM1 SREBF2 CHD9 CREBBP MED12

5.17e-0584685M1008
PathwayREACTOME_RORA_ACTIVATES_GENE_EXPRESSION

CARM1 CHD9 CREBBP

8.32e-0518683M26942
PathwayREACTOME_REGULATION_OF_CHOLESTEROL_BIOSYNTHESIS_BY_SREBP_SREBF

CARM1 SREBF2 CHD9 CREBBP

1.40e-0455684M27001
PathwayREACTOME_ADIPOGENESIS

CARM1 SREBF2 CHD9 CREBBP MED12

1.86e-04110685M48259
PathwayREACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_GENE_EXPRESSION

CARM1 CHD9 CREBBP

2.89e-0427683M26943
PathwayWP_KETOGENESIS_AND_KETOLYSIS

SLC25A20 UCP2

6.30e-048682M39836
PathwayREACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN

CSNK2A1 RUNX1 CBX2

7.42e-0437683M27797
PathwayREACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES

SLC5A6 SLC28A1 SLC29A4

1.00e-0341683MM15075
PathwayREACTOME_FORMATION_OF_THE_POSTERIOR_NEURAL_PLATE

SOX2 GBX2

1.01e-0310682M48036
PathwayREACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES

SLC5A6 SLC28A1 SLC29A4

1.15e-0343683M881
PathwayBIOCARTA_CARM1_PATHWAY

CARM1 CREBBP

1.23e-0311682MM1521
PathwayREACTOME_FORMATION_OF_THE_ANTERIOR_NEURAL_PLATE

SOX2 GBX2

1.23e-0311682M48031
PathwayREACTOME_TRANSPORT_OF_NUCLEOSIDES_AND_FREE_PURINE_AND_PYRIMIDINE_BASES_ACROSS_THE_PLASMA_MEMBRANE

SLC28A1 SLC29A4

1.23e-0311682MM15471
PathwayKEGG_ABC_TRANSPORTERS

ABCG1 ABCB8 ABCG5

1.23e-0344683M11911
PathwayREACTOME_TRANSPORT_OF_NUCLEOSIDES_AND_FREE_PURINE_AND_PYRIMIDINE_BASES_ACROSS_THE_PLASMA_MEMBRANE

SLC28A1 SLC29A4

1.47e-0312682M27728
PathwayBIOCARTA_CARM1_PATHWAY

CARM1 CREBBP

1.47e-0312682M7968
Pubmed

Interaction of HuDA and PABP at 5'UTR of mouse insulin2 regulates insulin biosynthesis.

PABPC3 ELAVL4 PABPC1

1.56e-07588329590218
Pubmed

Physical and functional link of the leukemia-associated factors AML1 and PML.

RUNX2 RUNX1 CREBBP

5.44e-07788315331439
Pubmed

Similar effects of all WNK3 variants on SLC12 cotransporters.

SLC12A1 SLC12A3 SLC12A5

8.69e-07888321613606
Pubmed

Cation-chloride cotransporters and neuronal function.

SLC12A1 SLC12A3 SLC12A5

1.30e-06988319323993
Pubmed

Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.

CARM1 ABCG1 UCP2 AGT SREBF2 CREBBP ABCG5

3.53e-0625088718660489
Pubmed

The arginine methyltransferase CARM1 regulates the coupling of transcription and mRNA processing.

CARM1 PABPC3 PABPC1

4.40e-061388317218272
Pubmed

E protein silencing by the leukemogenic AML1-ETO fusion protein.

TAF4 RUNX1 CREBBP

5.58e-061488315333839
Pubmed

Proteomic Analysis of Mouse Oocytes Identifies PRMT7 as a Reprogramming Factor that Replaces SOX2 in the Induction of Pluripotent Stem Cells.

SOX2 PRMT7

6.33e-06288227225728
Pubmed

The cDNA cloning of the transcripts of human PEBP2alphaA/CBFA1 mapped to 6p12.3-p21.1, the locus for cleidocranial dysplasia.

RUNX2 RUNX1

6.33e-0628829233771
Pubmed

Induction of Fc gammaRIIA expression in myeloid PLB cells during differentiation depends on cytosolic phospholipase A2 activity and is regulated via activation of CREB by PGE2.

FCGR2A CREBBP

6.33e-06288216709925
Pubmed

Breast cancer risk-associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression.

TOX3 FOXA1

6.33e-06288223001124
Pubmed

Mylk3 null C57BL/6N mice develop cardiomyopathy, whereas Nnt null C57BL/6J mice do not.

MYLK3 NNT

6.33e-06288232213617
Pubmed

Dysregulation of glucose homeostasis in nicotinamide nucleotide transhydrogenase knockout mice is independent of uncoupling protein 2.

UCP2 NNT

6.33e-06288219539600
Pubmed

The promoter of the Poly(A) binding protein 2 (Pabp2) retroposon is derived from the 5'-untranslated region of the Pabp1 progenitor gene.

PABPC3 PABPC1

6.33e-06288210534404
Pubmed

Urinary exosomes in the diagnosis of Gitelman and Bartter syndromes.

SLC12A1 SLC12A3

6.33e-06288225422309
Pubmed

Nucleotide sequence of a mouse testis poly(A) binding protein cDNA.

PABPC3 PABPC1

6.33e-0628821630930
Pubmed

Developmental expression of poly(A) binding protein mRNAs during spermatogenesis in the mouse.

PABPC3 PABPC1

6.33e-0628827893484
Pubmed

Runx1/AML1/Cbfa2 mediates onset of mesenchymal cell differentiation toward chondrogenesis.

RUNX2 RUNX1

6.33e-06288216059634
Pubmed

The transcriptional regulation of SOX2 on FOXA1 gene and its application in diagnosis of human breast and lung cancers.

SOX2 FOXA1

6.33e-06288225016694
Pubmed

Characterization of two cytoplasmic poly(A)-binding proteins, PABPC1 and PABPC2, in mouse spermatogenic cells.

PABPC3 PABPC1

6.33e-06288219020299
Pubmed

RUNX1 and RUNX2 transcription factors function in opposing roles to regulate breast cancer stem cells.

RUNX2 RUNX1

6.33e-06288232180230
Pubmed

Disease mutations in RUNX1 and RUNX2 create nonfunctional, dominant-negative, or hypomorphic alleles.

RUNX2 RUNX1

6.33e-06288217290219
Pubmed

SLC35E2 promoter mutation as a prognostic marker of esophageal squamous cell carcinoma.

SLC35E2A SLC35E2B

6.33e-06288235247439
Pubmed

CARM1 regulates proliferation of PC12 cells by methylating HuD.

CARM1 ELAVL4

6.33e-06288216508003
Pubmed

CARM1 mediates modulation of Sox2.

SOX2 CARM1

6.33e-06288222046437
Pubmed

Functional compensation for the loss of testis-specific poly(A)-binding protein, PABPC2, during mouse spermatogenesis.

PABPC3 PABPC1

6.33e-06288226971890
Pubmed

Runx1 and Runx2 inhibit fibrotic conversion of cellular niches for hematopoietic stem cells.

RUNX2 RUNX1

6.33e-06288235551452
Pubmed

Prospective evaluation of gene mutations and minimal residual disease in patients with core binding factor acute myeloid leukemia.

RUNX2 RUNX1

6.33e-06288223321257
Pubmed

Levels of free PABP are limited by newly polyadenylated mRNA in early Spisula embryogenesis.

PABPC3 PABPC1

6.33e-06288210954604
Pubmed

The mouse gene encoding the testis-specific isoform of Poly(A) binding protein (Pabp2) is an expressed retroposon: intimations that gene expression in spermatogenic cells facilitates the creation of new genes.

PABPC3 PABPC1

6.33e-0628829732454
Pubmed

Control of CBP co-activating activity by arginine methylation.

CARM1 CREBBP

6.33e-06288212374746
Pubmed

Expression of AML/Runx and ETO/MTG family members during hematopoietic differentiation of embryonic stem cells.

RUNX2 RUNX1

6.33e-06288217533052
Pubmed

A microRNA/Runx1/Runx2 network regulates prostate tumor progression from onset to adenocarcinoma in TRAMP mice.

RUNX2 RUNX1

6.33e-06288227634876
Pubmed

From Fish Physiology to Human Disease: The Discovery of the NCC, NKCC2, and the Cation-Coupled Chloride Cotransporters.

SLC12A1 SLC12A3

6.33e-06288237968800
Pubmed

Foxa1-deficient mice exhibit impaired insulin secretion due to uncoupled oxidative phosphorylation.

UCP2 FOXA1

6.33e-06288217003337
Pubmed

Molecular cloning, primary structure, and characterization of two members of the mammalian electroneutral sodium-(potassium)-chloride cotransporter family expressed in kidney.

SLC12A1 SLC12A3

6.33e-0628828021284
Pubmed

Identification and expression of a novel 3'-exon of mouse Runx1/Pebp2alphaB/Cbfa2/AML1 gene.

RUNX2 RUNX1

6.33e-06288210903914
Pubmed

Thalamo-cortical axons regulate the radial dispersion of neocortical GABAergic interneurons.

SLC17A7 GBX2 SLC12A5

8.56e-061688327935475
Pubmed

JAKMIP1, a Novel Regulator of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse.

PABPC3 GRIN2B PABPC1

1.04e-051788326627310
Pubmed

Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort.

CARM1 FOXA1 CREBBP

1.04e-051788319183483
Pubmed

Comprehensive analysis of low-abundance proteins in human urinary exosomes using peptide ligand library technology, peptide OFFGEL fractionation and nanoHPLC-chip-MS/MS.

SLC12A1 SLC12A3 NAGLU

1.04e-051788321082674
Pubmed

An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis.

SREBF2 CREBBP MED12

1.47e-051988316799563
Pubmed

A census of human transcription factors: function, expression and evolution.

SOX2 ATF7 TOX4 TOX3 SREBF2 GBX2 RUNX2 CAMTA1 RUNX1 FOXA1 RFX2

1.86e-05908881119274049
Pubmed

Co-activator activator (CoAA) prevents the transcriptional activity of Runt domain transcription factors.

RUNX2 RUNX1

1.90e-05388219585539
Pubmed

TOX3 regulates neural progenitor identity.

SOX2 TOX3

1.90e-05388227080130
Pubmed

Embryonic Poly(A)-Binding Protein Is Required During Early Stages of Mouse Oocyte Development for Chromatin Organization, Transcriptional Silencing, and Meiotic Competence.

PABPC3 PABPC1

1.90e-05388226134869
Pubmed

Expression of Runx1, -2 and -3 during tooth, palate and craniofacial bone development.

RUNX2 RUNX1

1.90e-05388214516670
Pubmed

Human testis expresses a specific poly(A)-binding protein.

PABPC3 PABPC1

1.90e-05388211328870
Pubmed

Role of FOXA and Sp1 in mitochondrial acylcarnitine carrier gene expression in different cell lines.

SLC25A20 FOXA1

1.90e-05388221130740
Pubmed

Cardiovascular expression of the mouse WNK1 gene during development and adulthood revealed by a BAC reporter assay.

SLC12A1 SLC12A3

1.90e-05388216816365
Pubmed

Enforced expression of Runx2 perturbs T cell development at a stage coincident with beta-selection.

RUNX2 RUNX1

1.90e-05388212218099
Pubmed

Superovulation alters embryonic poly(A)-binding protein (Epab) and poly(A)-binding protein, cytoplasmic 1 (Pabpc1) gene expression in mouse oocytes and early embryos.

PABPC3 PABPC1

1.90e-05388225034140
Pubmed

SIRT1 Functions as a Negative Regulator of Eukaryotic Poly(A)RNA Transport.

PABPC3 PABPC1

1.90e-05388228756945
Pubmed

The poly(A)-binding protein genes, EPAB, PABPC1, and PABPC3 are differentially expressed in infertile men with non-obstructive azoospermia.

PABPC3 PABPC1

1.90e-05388226843391
Pubmed

Mechanisms of ammonia and ammonium transport by rhesus-associated glycoproteins.

RHBG RHAG

1.90e-05388226354748
Pubmed

Nuclear relocalisation of cytoplasmic poly(A)-binding proteins PABP1 and PABP4 in response to UV irradiation reveals mRNA-dependent export of metazoan PABPs.

PABPC3 PABPC1

1.90e-05388221940797
Pubmed

Glutamine rich and basic region/leucine zipper (bZIP) domains stabilize cAMP-response element-binding protein (CREB) binding to chromatin.

TAF4 CREBBP

1.90e-05388215703171
Pubmed

RUNX1 (AML-1) and RUNX2 (AML-3) cooperate with prostate-derived Ets factor to activate transcription from the PSA upstream regulatory region.

RUNX2 RUNX1

1.90e-05388216237704
Pubmed

Contributions of rare coding variants in hypotension syndrome genes to population blood pressure variation.

SLC12A1 SLC12A3

1.90e-05388230113482
Pubmed

Downregulation of NCC and NKCC2 cotransporters by kidney-specific WNK1 revealed by gene disruption and transgenic mouse models.

SLC12A1 SLC12A3

1.90e-05388221131289
Pubmed

Relative CO₂/NH₃ permeabilities of human RhAG, RhBG and RhCG.

RHBG RHAG

1.90e-05388224077989
Pubmed

Neurobeachin and the Kinesin KIF21B Are Critical for Endocytic Recycling of NMDA Receptors and Regulate Social Behavior.

NBEA GRIN2B

1.90e-05388229847800
Pubmed

AML1, AML2, and AML3, the human members of the runt domain gene-family: cDNA structure, expression, and chromosomal localization.

RUNX2 RUNX1

1.90e-0538827835892
Pubmed

The mouse Y-box protein, MSY2, is associated with a kinase on non-polysomal mouse testicular mRNAs.

PABPC3 PABPC1

1.90e-05388210076007
Pubmed

Cloning and characterization of subunits of the T-cell receptor and murine leukemia virus enhancer core-binding factor.

RUNX2 RUNX1

1.90e-0538828497254
Pubmed

Epab and Pabpc1 are differentially expressed during male germ cell development.

PABPC3 PABPC1

1.90e-05388222814100
Pubmed

AML3/CBFalpha1 is required for androgen-specific activation of the enhancer of the mouse sex-limited protein (Slp) gene.

RUNX2 RUNX1

1.90e-05388210521447
Pubmed

Antagonistic Functions of USAG-1 and RUNX2 during Tooth Development.

SOX2 RUNX2

1.90e-05388227518316
Pubmed

Clusterin/apolipoprotein J attenuates angiotensin II-induced renal fibrosis.

AGT SLC12A5

1.90e-05388225148511
Pubmed

De novo variants in the PABP domain of PABPC1 lead to developmental delay.

PABPC3 PABPC1

1.90e-05388235511136
Pubmed

Mediator modulates Gli3-dependent Sonic hedgehog signaling.

CREBBP MED12

1.90e-05388217000779
Pubmed

Glucose-stimulated PGC-1α couples with CBP and Runx2 to mediate intervertebral disc degeneration through transactivation of ADAMTS4/5 in diet-induced obesity mice.

RUNX2 CREBBP

1.90e-05388236403758
Pubmed

Inhibition of CK2 mitigates Alzheimer's tau pathology by preventing NR2B synaptic mislocalization.

CSNK2A1 GRIN2B

1.90e-05388235246269
Pubmed

Non-association of the thiazide-sensitive Na,Cl-cotransporter gene with polygenic hypertension in both rats and humans.

SLC12A1 SLC12A3

1.90e-05388211564973
Pubmed

Epab is dispensable for mouse spermatogenesis and male fertility.

PABPC3 PABPC1

1.90e-05388224599567
Pubmed

Lipopolysaccharide inhibits colonic biotin uptake via interference with membrane expression of its transporter: a role for a casein kinase 2-mediated pathway.

CSNK2A1 SLC5A6

1.90e-05388228052864
Pubmed

Differential 3' Processing of Specific Transcripts Expands Regulatory and Protein Diversity Across Neuronal Cell Types.

PABPC3 PABPC1

1.90e-05388229578408
Pubmed

Domain-functional analyses of PIWIL1 and PABPC1 indicate their synergistic roles in protein translation via 3'-UTRs of meiotic mRNAs.

PABPC3 PABPC1

1.90e-05388229701755
Pubmed

The murine myeloperoxidase promoter contains several functional elements, one of which binds a cell type-restricted transcription factor, myeloid nuclear factor 1 (MyNF1).

RUNX2 RUNX1

1.90e-0538828384306
Pubmed

Translation repression via modulation of the cytoplasmic poly(A)-binding protein in the inflammatory response.

PABPC3 PABPC1

1.90e-05388228635594
Pubmed

Aberrant activation of CYR61 enhancers in colorectal cancer development.

FOXA1 CREBBP

1.90e-05388231118064
Pubmed

The RUNX1 Runt domain at 1.25A resolution: a structural switch and specifically bound chloride ions modulate DNA binding.

RUNX2 RUNX1

1.90e-05388212217689
Pubmed

Interplay among coactivator-associated arginine methyltransferase 1, CBP, and CIITA in IFN-gamma-inducible MHC-II gene expression.

CARM1 CREBBP

1.90e-05388216254053
Pubmed

Shared and distinct roles mediated through C-terminal subdomains of acute myeloid leukemia/Runt-related transcription factor molecules in murine development.

RUNX2 RUNX1

1.90e-05388215713794
Pubmed

Metastatic breast cancer cells inhibit osteoblast differentiation through the Runx2/CBFβ-dependent expression of the Wnt antagonist, sclerostin.

RUNX2 RUNX1

1.90e-05388222032690
Pubmed

Genetic regulation of the RUNX transcription factor family has antitumor effects.

RUNX2 RUNX1

1.90e-05388228530640
Pubmed

Epab and Pabpc1 are differentially expressed in the postnatal mouse ovaries.

PABPC3 PABPC1

1.90e-05388225370180
Pubmed

FNDC5/irisin facilitates muscle-adipose-bone connectivity through ubiquitination-dependent activation of runt-related transcriptional factors RUNX1/2.

RUNX2 RUNX1

1.90e-05388235124008
Pubmed

Regulation of tissue inhibitor of metalloproteinase 1 gene transcription by RUNX1 and RUNX2.

RUNX2 RUNX1

1.90e-05388215051730
Pubmed

Identification and comparative analysis of a second runx3 promoter.

RUNX2 RUNX1

1.90e-05388211483356
Pubmed

Cytoplasmic poly(A)-binding protein 1 (PABPC1) interacts with the RNA-binding protein hnRNPLL and thereby regulates immunoglobulin secretion in plasma cells.

PABPC3 PABPC1

1.90e-05388228611064
Pubmed

OS9 Protein Interacts with Na-K-2Cl Co-transporter (NKCC2) and Targets Its Immature Form for the Endoplasmic Reticulum-associated Degradation Pathway.

SLC12A1 SLC12A3

1.90e-05388226721884
Pubmed

A twin UGUA motif directs the balance between gene isoforms through CFIm and the mTORC1 signaling pathway.

PABPC3 PABPC1

1.90e-05388237665675
Pubmed

PEBP2/CBF, the murine homolog of the human myeloid AML1 and PEBP2 beta/CBF beta proto-oncoproteins, regulates the murine myeloperoxidase and neutrophil elastase genes in immature myeloid cells.

RUNX2 RUNX1

1.90e-0538828035830
Pubmed

Human Rhesus B and Rhesus C glycoproteins: properties of facilitated ammonium transport in recombinant kidney cells.

RHBG RHAG

1.90e-05388215929723
Pubmed

ABCG1 and ABCG4 are coexpressed in neurons and astrocytes of the CNS and regulate cholesterol homeostasis through SREBP-2.

ABCG1 SREBF2

1.90e-05388217916878
Pubmed

RUNX1 and RUNX2 upregulate Galectin-3 expression in human pituitary tumors.

RUNX2 RUNX1

1.90e-05388219020999
Pubmed

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

CARM1 ZNF827 RUNX1 NSMCE3 CREBBP MED12 CDH13 CBX2

2.01e-0545388829656893
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TKFC ZNF827 ZMIZ2 KHNYN NAGLU ZNRF1 GBX2 MICAL3 SLC35E2B MED12 CYB5R2 CBX2

2.22e-051105881235748872
Pubmed

Identification of Modifier Genes in a Mouse Model of Gaucher Disease.

TOX3 GRIN2B TRUB1

2.33e-052288327568557
InteractionCREB1 interactions

SOX2 CARM1 ATF7 TOX4 CSNK2A1 SREBF2 TAF4 FOXA1 CREBBP

1.13e-06254849int:CREB1
GeneFamilySolute carriers

SLC25A20 SLC12A1 SLC12A3 RHBG SLC35E2A SLC6A17 SLC5A6 UCP2 SLC28A1 SLC17A7 SLC35E2B SLC29A4 RHAG SLC12A5

3.98e-113956114752
GeneFamilyBlood group antigens|CD molecules|ATP binding cassette subfamily G

ABCG1 ABCG5

1.11e-045612811
GeneFamilyProtein arginine methyltransferases

CARM1 PRMT7

3.97e-049612691
GeneFamilyCD molecules|Mucins

MUC16 MUC3A

2.26e-0321612648
GeneFamilyAtaxins|Trinucleotide repeat containing

TOX3 MED12

3.20e-0325612775
GeneFamilyRNA binding motif containing

PABPC3 RAVER2 ELAVL4 PABPC1

5.79e-03213614725
GeneFamilyOlfactory receptors, family 2

OR2T35 OR2C3 OR2T2

6.58e-03113613149
GeneFamilySerpin peptidase inhibitors

AGT SERPINA10

6.91e-0337612739
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TKFC AGT SERPINA10 NNT ABCG5 ITIH1

7.84e-07160886c42bcc6c7d113f0db43febb088b75ca4ac7cb7a3
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TKFC AGT SERPINA10 NNT ITIH1

2.09e-05168885b98af4043dfa5dfa4413e482879fad88de484675
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TKFC AGT SERPINA10 NNT ITIH1

2.09e-05168885073b53d4cee6bc8c5c6fce51cf6cd9c316478f69
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Rxfp1_Eya1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CDH13 CYB5R2 RHAG OTOG

2.13e-058288442017b8ace6f142a8358213c95a2632226c3a867
ToppCelldroplet-Liver-HEPATOCYTES|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TKFC AGT SERPINA10 NNT ITIH1

2.15e-05169885f195467438c589f87224bde7da720dea072d110c
ToppCelldroplet-Liver-HEPATOCYTES-1m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TKFC AGT SERPINA10 NNT ITIH1

2.15e-051698857785cab967a33560830c394c918d6ce625103858
ToppCell5'-Adult-LargeIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ELAVL4 GBX2 SERPINA10 SLC29A4 SLC12A5

2.40e-051738859a3500b06d00d1d4ee42910a3a73327b21beab52
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TKFC AGT NNT ABCG5 ITIH1

2.54e-051758855c38d4b6c03473d841e6203a7efaa6dcb2d59386
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TOX3 SREBF2 NBEA RUNX2 FOXA1

2.61e-051768853bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 SLC6A17 ELAVL4 GRIN2B OTOG

3.22e-051848852cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 SLC6A17 ELAVL4 GRIN2B OTOG

3.22e-05184885ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 SLC6A17 ELAVL4 GRIN2B OTOG

3.22e-051848852b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell18-Distal-Epithelial-Secretory_progenitor|Distal / Age, Tissue, Lineage and Cell class

SOX2 FCGR2A UCP2 RUNX1 FOXA1

3.95e-051928859fae988ecd2ef1231bfd42a678a4903517694cbe
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A17 SLC17A7 ELAVL4 GRIN2B SLC12A5

4.05e-05193885461919ab422bc9d1fcff7a3a4757c75239041d7e
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A17 SLC17A7 ELAVL4 GRIN2B SLC12A5

4.05e-051938850dd810ad900d3e586551622b2c1de39d76fd6a7f
ToppCellPosterior_cortex-Neuronal|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SLC6A17 ELAVL4 NBEA GRIN2B SLC12A5

4.05e-05193885b4989e3436e84dbec3789b46057e0f7a0ebf09d4
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage1_(2)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ABCG1 FCGR2A UCP2 ELAVL4 RUNX1

4.15e-05194885846b4170544cdf58b536fb7a5fd34b79b0b17993
ToppCellBrain_organoid-organoid_Velasco_nature-3_mon-Neuronal-CFuPNs|3_mon / Sample Type, Dataset, Time_group, and Cell type.

CLCN4 SLC17A7 NBEA GRIN2B ARMH4

4.25e-05195885574354ef4bcefeb9856b65d19bb92e2cffe5dc7a
ToppCell15-Trachea|15 / Age, Tissue, Lineage and Cell class

SOX2 UCP2 MUC16 RUNX1 FOXA1

4.36e-05196885fd17403422cf95c24f6be1c2d78764bb352f7f2e
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon|organoid_Paulsen_bioRxiv / Sample Type, Dataset, Time_group, and Cell type.

CLCN4 SLC17A7 ELAVL4 NBEA GRIN2B

4.46e-05197885a97556e9fbb24272de51f54ecda6ab9ccb97a61e
ToppCellFetal_29-31_weeks-Epithelial-club_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TOX3 SREBF2 NBEA RUNX2 FOXA1

4.57e-051988855fc25b008a4d8d6bec83923a16f64dd9e1ff1f2d
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-cortical_neurons_1|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

CLCN4 SLC17A7 ELAVL4 NBEA GRIN2B

4.57e-05198885d81f35c0066558ff96dd06f58fca72cd82e681e8
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

UCP2 TOX3 MUC16 NBEA FOXA1

4.68e-051998857223f853335492ca617dbec3e4b6872a8a463a45
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCG1 FCGR2A KIF16B SLC28A1 OSBPL11

4.68e-05199885fde8e3ba19d19069a4d3b8db55bfe6220cf634d5
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Goblet|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

UCP2 TOX3 MUC16 NBEA FOXA1

4.68e-05199885e03bdc7cb825e287f41b834ec6061d23c1c03b04
ToppCellFrontal_cortex-Neuronal|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ELAVL4 NBEA GRIN2B CAMTA1 SLC12A5

4.68e-05199885f88039d862f3bfa01dc39d2de4f3f548dc5a0e61
ToppCellParenchyma_Control_(B.)-Immune-TX-TRAM-2|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

ABCG1 FCGR2A UCP2 KIF16B OSBPL11

4.79e-052008857c56935446f10d202eafa1f9ee7cb0aae4c2607e
ToppCellParenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TOX3 MUC16 NBEA RUNX2 RUNX1

4.79e-05200885b992eeddee38e6fe3564e9b1850f6b20b89bf47d
ToppCellTracheal|World / Cell types per location group and 10X technology with lineage, and cell group designations

SOX2 RAVER2 TOX3 MUC16 NBEA

4.79e-05200885682960e28542a3d6c119047cd0131941932cfdea
ToppCellTracheal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RAVER2 TOX3 SREBF2 MUC16 NBEA

4.79e-05200885d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Macroglial-Astrocyte|GW10 / Sample Type, Dataset, Time_group, and Cell type.

SOX2 RAVER2 TOX3 GRIN2B PRMT7

4.79e-0520088598a994692440cb4f505b050276f0c8022c814a21
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Macroglial|GW10 / Sample Type, Dataset, Time_group, and Cell type.

SOX2 RAVER2 TOX3 GRIN2B PRMT7

4.79e-05200885ef222dc4a205d670172dae74990bdb952ac92e5b
Diseasecarotid artery disease (is_implicated_in)

UCP2 AGT SREBF2

3.18e-0522833DOID:3407 (is_implicated_in)
DiseaseSeizures

CSNK2A1 SLC5A6 AGT SLC17A7 NBEA SLC12A5

3.57e-05218836C0036572
Diseasebreast cancer (is_implicated_in)

SOX2 AGT CYB5R3 FOXA1 CDH13

6.70e-05150835DOID:1612 (is_implicated_in)
Diseasehemolytic anemia (is_implicated_in)

FCGR2A RHAG

2.16e-048832DOID:583 (is_implicated_in)
DiseaseAmyotrophic Lateral Sclerosis, Familial

GBX2 CREBBP OTOG

3.39e-0448833C4551993
DiseaseAmyotrophic Lateral Sclerosis, Sporadic

GBX2 CREBBP OTOG

3.39e-0448833C1862941
DiseaseProstatic Neoplasms

SOX2 NAGLU RUNX1 FOXA1 CREBBP ABCG5 MED12 CDH13

3.44e-04616838C0033578
DiseaseMalignant neoplasm of prostate

SOX2 NAGLU RUNX1 FOXA1 CREBBP ABCG5 MED12 CDH13

3.44e-04616838C0376358
DiseaseAMYOTROPHIC LATERAL SCLEROSIS 1

GBX2 CREBBP OTOG

3.82e-0450833C1862939
DiseaseHerpes Zoster, response to tofacitinib

TOX3 ACSF3

5.07e-0412832EFO_0006510, EFO_0600024
Diseasemigraine disorder

ATF7 NBEA CAMTA1 RUNX1 CDH13 ARMH4

5.19e-04357836MONDO_0005277
Diseasemean platelet volume

TOX4 ZMIZ2 UCP2 KIF16B CYB5R3 CHD9 CAMTA1 RUNX1 RFX2 NNT

5.77e-0410208310EFO_0004584
Diseasepallidum volume change measurement

SLC28A1 CDH13

5.98e-0413832EFO_0021494
Disease3-hydroxyphenylacetic acid measurement

PIEZO2 RUNX1

6.96e-0414832EFO_0010448
Diseaserheumatoid arthritis, ACPA-positive rheumatoid arthritis, rheumatoid factor seropositivity measurement

FCGR2A ACSF3 RUNX1

7.55e-0463833EFO_0000685, EFO_0007791, EFO_0009459
Diseasecholangiocarcinoma (is_marker_for)

SOX2 MUC16 MUC3A

7.90e-0464833DOID:4947 (is_marker_for)
DiseaseSchizophrenia

PLAA UCP2 SREBF2 SLC17A7 ESAM GRIN2B MED12 ITIH1 SLC12A5

8.40e-04883839C0036341
DiseaseMalignant neoplasm of breast

ABCB8 TOX3 KIF16B SREBF2 SLC28A1 OSBPL11 FOXA1 RFX2 PABPC1 MED12

8.58e-0410748310C0006142
Diseasenon-word reading

SLC12A3 ZMIZ2 CDH13

9.03e-0467833EFO_0005299
DiseaseHypercholesterolemia, Familial

SREBF2 ABCG5

1.16e-0318832C0020445
Diseaseepilepsy (implicated_via_orthology)

SLC12A1 SLC12A3 GRIN2B SLC12A5

1.17e-03163834DOID:1826 (implicated_via_orthology)
DiseaseEsophageal Neoplasms

SOX2 CDH13 MAP3K3

1.40e-0378833C0014859
DiseaseOsteoarthritis of hip

RUNX2 ITIH1

1.44e-0320832C0029410
DiseaseAllodynia

AGT GRIN2B SLC12A5

1.74e-0384833C0458247
DiseaseMechanical Allodynia

AGT GRIN2B SLC12A5

1.74e-0384833C2936719
DiseaseHyperalgesia, Secondary

AGT GRIN2B SLC12A5

1.74e-0384833C0751212
DiseaseHyperalgesia, Primary

AGT GRIN2B SLC12A5

1.74e-0384833C0751211
DiseaseHyperalgesia, Thermal

AGT GRIN2B SLC12A5

1.74e-0384833C0751214
DiseaseTactile Allodynia

AGT GRIN2B SLC12A5

1.74e-0384833C0751213
DiseaseHyperalgesia

AGT GRIN2B SLC12A5

1.74e-0384833C0020429
Diseasebreast cancer (is_marker_for)

SOX2 CSNK2A1 AGT CDH13

1.87e-03185834DOID:1612 (is_marker_for)
DiseaseRenal glomerular disease

SLC12A3 CREBBP

1.90e-0323832C0268731
DiseaseGlomerulopathy Assessment

SLC12A3 CREBBP

1.90e-0323832C4521256
DiseaseC-reactive protein measurement

CARM1 ZMIZ2 SLC5A6 RAVER2 NAGLU MICAL3 SERPINA10 TAF4 CAMTA1 ARMH4

2.03e-0312068310EFO_0004458
DiseaseParkinson disease

FCGR2A RTL9 NAGLU ITIH1 CDH13

2.15e-03321835MONDO_0005180
Diseasechronic myeloid leukemia (is_marker_for)

FCGR2A AGT

2.62e-0327832DOID:8552 (is_marker_for)
Diseasesciatic neuropathy (biomarker_via_orthology)

SLC17A7 ELAVL4 GRIN2B

2.77e-0399833DOID:11446 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
PVVTGVSGMAVASVM

CAMTA1

376

Q9Y6Y1
IMGPSGAGKSTLMNI

ABCG1

116

P45844
MSGMLVPVGVGIAGA

ARMH4

711

Q86TY3
QVPSMGSSSPMGIIV

FCGR2A

206

P12318
TGMGTPGSQMAPVSL

CREBBP

1986

Q92793
MTSLVGMNIPGHTGT

ELAVL4

286

P26378
GMTEIGMALSGPLTT

ACSF3

356

Q4G176
GMVVGTASTMVTARP

ATF7

276

P17544
PSMAVGAIAGRMVGI

CLCN4

471

P51793
IGHVMEGSPTGTTVM

CDH13

251

P55290
STSVSVPMLSGMGTF

AGT

296

P01019
STMVGTGMAPEGISQ

NAGLU

436

P54802
TMMGNSGDSGLIPRI

KIF16B

111

Q96L93
PTQTTITAGMGMLPF

RAVER2

476

Q9HCJ3
GMIAGGTGITPMLQV

CYB5R3

176

P00387
GMIAGGTGITPMLQL

CYB5R2

151

Q6BCY4
GGVVMCSGPSMEPTI

IMMP1L

31

Q96LU5
PFGTITSAKVMMEGG

PABPC1

316

P11940
SMAGTMGLLVTSAPG

MUC16

1676

Q8WXI7
TESGGMILAMQTSPP

MUC16

4086

Q8WXI7
VGGSLDGFMLTPVTM

OR2T2

151

Q6IF00
GISPIMTGKEMASVG

MICAL3

591

Q7RTP6
GFVTPLTSMSIRGMA

ITIH1

601

P19827
VISLGTGPQLTPGMM

GAPVD1

516

Q14C86
MGSIMSTGIVQGSSG

CARM1

551

Q86X55
MMSPDLPIGQTVGST

DSG4

1006

Q86SJ6
ITPSSVGISGSLPMM

MUC3A

826

Q02505
VGISGSLPMMTDLTS

MUC3A

831

Q02505
GEMLMTGRGSLGPTL

MYLK3

346

Q32MK0
AGMLSGVFTTGIMTP

SLC25A20

116

O43772
GVLPTTMTGVMGLEP

MED12

1876

Q93074
GGSLDGFMLTPVTMS

OR2T35

151

Q8NGX2
LGGLTTSMVGSTLTM

OR2C3

151

Q8N628
LGGLVTTVTFTGMMR

MFSD3

331

Q96ES6
PFGTITSAKVMMEGG

PABPC3

316

Q9H361
MTAAGVTAMGTALSP

FOXA1

96

P55317
VTAMGTALSPSGMGA

FOXA1

101

P55317
QVTAGLMGMPTGLPS

CHD9

2686

Q3L8U1
QGMALTSTLMATLPG

GBX2

96

P52951
MAAPGALLVMGVSGS

IDNK

1

Q5T6J7
SLMKGMASSPGRGGI

CBX2

236

Q14781
IGTGTGLLSMMAVTA

PRMT7

71

Q9NVM4
MGDLSSLTPGGSMGL

ABCG5

1

Q9H222
GGSTPVSSANMMSGI

CSNK2A1

341

P68400
SSSGLSRMGAVPVMV

ESAM

366

Q96AP7
PGSLMISGLTEAFVM

KHNYN

116

O15037
MTQPPASTSGIMGTL

CA5BP1

1

Q8WTZ4
TICMSGTGMRSVTGT

MAP3K3

516

Q99759
GMSIGVTMVGEGILS

OSBPL11

541

Q9BXB4
GMTSVGLADGTPIDM

SLC12A5

396

Q9H2X9
LQTPTPGMVSGAMET

OTOG

1586

Q6ZRI0
ATPALMGVGTLMGSG

ABCB8

301

Q9NUT2
PARMATVVLGGDTMG

MEA1

11

Q16626
MSGAMALGGTIGLTI

NNT

676

Q13423
GAAMSPATGAMSIAT

GARIN3

286

Q8TC56
TPVTSGIGIGMSAMG

RUNX1

331

Q01196
TPPVTSGMSLGMSAT

RUNX2

401

Q13950
GALSMPQMTDTASGG

RTL9

651

Q8NET4
ASMVIGPTMQGALPS

TAF4

371

O00268
GTPGMALGSMGSVVK

SOX2

231

P48431
MQVSGGGPSISLVMK

TAPBPL

146

Q9BX59
SMVGITMDVGGSPIV

RFX2

131

P48378
GIGSIVTSMGSSMPP

SLC5A6

471

Q9Y289
RGASGSGSVMLPAGM

NBEA

46

Q8NFP9
SGSVMLPAGMINPSV

NBEA

51

Q8NFP9
GGEPSMLGAVQMLST

SLC35E2A

101

P0CK97
MSMVSGFGPLITAGI

SLC12A1

486

Q13621
ILMGISNGVGTLSGM

SLC17A7

436

Q9P2U7
AVMGTVPGTGSIQMS

BRS3

366

P32247
LDTVLTGMMGGARPG

CDCA4

191

Q9BXL8
GVMGTILTMVRTEGP

UCP2

61

P55851
GVVVGTSSEMMLTPF

RHBG

291

Q9H310
LVGSSGTILTTMPVM

SREBF2

291

Q12772
VPGSASMGTTMAGVD

PLAA

501

Q9Y263
LGSSGMMLPSLTSSV

PIEZO2

231

Q9H5I5
SMIIGSIAGMVSVLG

RHAG

296

Q02094
TMSMVSGFAPLITAG

SLC12A3

446

P55017
GGEPSMLGAVQMLST

SLC35E2B

101

P0CK96
IGAPLISSMGTTMVG

TOX3

411

O15405
APLASGMMTGTIETT

TIGIT

16

Q495A1
EMRGDQGTPTTGLLM

NSMCE3

166

Q96MG7
SIGIMLGGLTSMVPQ

SLC28A1

546

O00337
SMMPGVAGGSSALTS

ZMIZ2

71

Q8NF64
SLAMTGLMLGATGPT

SERPINA10

106

Q9UK55
EGGGTELVGTMMTSN

ZNF827

491

Q17R98
GIGSGTKMLTSMLSG

TRUB1

131

Q8WWH5
GVMTGESTAGVMISL

SLC29A4

201

Q7RTT9
LGSMIGTMAGITTPI

SLC6A17

471

Q9H1V8
GTFMSALEMPGISLT

TKFC

301

Q3LXA3
PSSITMSQGGMVTVI

TOX4

376

O94842
VSSVAGMGMDPSTAG

ZNRF1

51

Q8ND25
TPILGIHGGSSMIMA

GRIN2B

121

Q13224