Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioninositol 1,4,5-trisphosphate-gated calcium channel activity

ITPR1 ITPR2 ITPR3

1.77e-083533GO:0005220
GeneOntologyMolecularFunctioninositol 1,4,5 trisphosphate binding

ITPR1 ITPR2 ITPR3

6.30e-0614533GO:0070679
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

ITPR1 ITPR2 ITPR3

1.40e-0518533GO:0015278
GeneOntologyMolecularFunctionligand-gated calcium channel activity

ITPR1 ITPR2 ITPR3

7.53e-0531533GO:0099604
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

ITPR1 ITPR2 ITPR3

9.11e-0533533GO:0005217
GeneOntologyMolecularFunctionalcohol binding

OSBPL10 ITPR1 ITPR2 ITPR3

1.55e-04102534GO:0043178
GeneOntologyMolecularFunctionmicrotubule motor activity

KIF26B DNAH9 KIF11

8.52e-0470533GO:0003777
GeneOntologyMolecularFunctionmicrotubule binding

KIF26B FES GOLGA8A KLC3 KIF11

1.32e-03308535GO:0008017
GeneOntologyMolecularFunctionphosphatidylinositol binding

FES EEA1 ITPR1 ITPR2 ITPR3

1.48e-03316535GO:0035091
GeneOntologyBiologicalProcessmicrotubule-based process

SLK ANK3 KIF26B TTC21A FES KLC4 GOLGA8A DNAH9 LYST KLC3 KIF11 CFAP46 DCTN3

1.96e-0610585313GO:0007017
GeneOntologyBiologicalProcessmicrotubule-based movement

ANK3 KIF26B TTC21A KLC4 DNAH9 KLC3 KIF11 CFAP46

3.47e-05493538GO:0007018
GeneOntologyCellularComponentplatelet dense tubular network membrane

ITPR1 ITPR2 ITPR3

1.28e-069533GO:0031095
GeneOntologyCellularComponentplatelet dense tubular network

ITPR1 ITPR2 ITPR3

2.50e-0611533GO:0031094
GeneOntologyCellularComponentmicrotubule associated complex

KLC4 DNAH9 KLC3 KIF11 DCTN3

5.42e-05161535GO:0005875
GeneOntologyCellularComponentsarcoplasmic reticulum

ANK3 ITPR1 ITPR2 ITPR3

7.33e-0588534GO:0016529
GeneOntologyCellularComponentsarcoplasm

ANK3 ITPR1 ITPR2 ITPR3

2.00e-04114534GO:0016528
GeneOntologyCellularComponentkinesin complex

KLC4 KLC3 KIF11

2.61e-0449533GO:0005871
GeneOntologyCellularComponentmicrotubule

KIF26B KLC4 GOLGA8A DNAH9 KLC3 KIF11 DCTN3

3.76e-04533537GO:0005874
HumanPhenoBilateral facial palsy

SYNE1 ITPR1

2.77e-053162HP:0430025
DomainInsP3_rcpt-bd

ITPR1 ITPR2 ITPR3

2.04e-083523IPR000493
DomainRIH_assoc

ITPR1 ITPR2 ITPR3

4.05e-076523PF08454
DomainRIH_assoc-dom

ITPR1 ITPR2 ITPR3

4.05e-076523IPR013662
DomainRYDR_ITPR

ITPR1 ITPR2 ITPR3

4.05e-076523PF01365
DomainRIH_dom

ITPR1 ITPR2 ITPR3

4.05e-076523IPR000699
DomainIns145_P3_rcpt

ITPR1 ITPR2 ITPR3

4.05e-076523IPR014821
DomainRyanodine_recept-rel

ITPR1 ITPR2 ITPR3

4.05e-076523IPR015925
DomainIns145_P3_rec

ITPR1 ITPR2 ITPR3

4.05e-076523PF08709
Domain-

ITPR1 ITPR2 ITPR3

4.05e-0765231.25.10.30
DomainMIR

ITPR1 ITPR2 ITPR3

2.41e-0610523PS50919
DomainMIR

ITPR1 ITPR2 ITPR3

2.41e-0610523PF02815
DomainMIR

ITPR1 ITPR2 ITPR3

2.41e-0610523SM00472
DomainMIR_motif

ITPR1 ITPR2 ITPR3

2.41e-0610523IPR016093
DomainKinesin_light

KLC4 KLC3

4.55e-054522IPR002151
DomainRabaptin_Rab5-bd_dom

KLC4 KLC3

1.13e-046522IPR015390
DomainRab5-bind

KLC4 KLC3

1.13e-046522PF09311
DomainBIR

NAIP BIRC6

2.11e-048522SM00238
DomainBIR_REPEAT_2

NAIP BIRC6

2.11e-048522PS50143
Domain-

NAIP BIRC6

2.11e-0485221.10.1170.10
DomainBIR_rpt

NAIP BIRC6

2.11e-048522IPR001370
DomainBIR_REPEAT_1

NAIP BIRC6

2.11e-048522PS01282
DomainBIR

NAIP BIRC6

2.11e-048522PF00653
DomainTPR

TTC21A KLC4 KLC3 CFAP46

1.14e-03165524PS50005
DomainTPR_REGION

TTC21A KLC4 KLC3 CFAP46

1.14e-03165524PS50293
DomainNACHT

NAIP NLRP4

1.85e-0323522PS50837
DomainNACHT_NTPase

NAIP NLRP4

1.85e-0323522IPR007111
DomainTPR_1

TTC21A KLC4 KLC3

2.02e-0390523PF00515
DomainTPR_1

TTC21A KLC4 KLC3

2.02e-0390523IPR001440
DomainARM-type_fold

ZNFX1 LYST CLHC1 ITPR1 ITPR2

2.47e-03339525IPR016024
Domain-

TTC21A KLC4 KLC3 CFAP46

2.62e-032075241.25.40.10
DomainIon_trans_dom

ITPR1 ITPR2 ITPR3

3.94e-03114523IPR005821
DomainIon_trans

ITPR1 ITPR2 ITPR3

3.94e-03114523PF00520
DomainTPR-like_helical_dom

TTC21A KLC4 KLC3 CFAP46

4.00e-03233524IPR011990
DomainCYCLIN

BRF1 CCND2

5.01e-0338522SM00385
Domain-

BRF1 CCND2

5.54e-03405221.10.472.10
DomainTPR

TTC21A KLC4 KLC3

5.56e-03129523SM00028
DomainTPR_repeat

TTC21A KLC4 KLC3

6.05e-03133523IPR019734
DomainCyclin-like

BRF1 CCND2

6.38e-0343522IPR013763
DomainKinesin-like_fam

KIF26B KIF11

6.38e-0343522IPR027640
DomainKINESIN_MOTOR_1

KIF26B KIF11

6.67e-0344522PS00411
Domain-

KIF26B KIF11

6.67e-03445223.40.850.10
DomainKinesin_motor_dom

KIF26B KIF11

6.67e-0344522IPR001752
DomainKinesin

KIF26B KIF11

6.67e-0344522PF00225
DomainKISc

KIF26B KIF11

6.67e-0344522SM00129
DomainKINESIN_MOTOR_2

KIF26B KIF11

6.67e-0344522PS50067
DomainSer-Thr/Tyr_kinase_cat_dom

NEK5 NEK8 FES

6.70e-03138523IPR001245
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKN_TO_MGLUR1_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

1.66e-075373M49000
PathwayKEGG_MEDICUS_REFERENCE_CA2_PLCD_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

3.31e-076373M47960
PathwayKEGG_MEDICUS_REFERENCE_BCR_PLCG_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

1.38e-069373M47852
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SPTBN2_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

1.97e-0610373M47661
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PRKCG_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

2.71e-0611373M49033
PathwayREACTOME_CLEC7A_DECTIN_1_INDUCES_NFAT_ACTIVATION

ITPR1 ITPR2 ITPR3

2.71e-0611373M27466
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN1_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

4.68e-0613373M47696
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_SIGMAR1_TO_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

4.68e-0613373M47751
PathwayKEGG_MEDICUS_REFERENCE_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

4.68e-0613373M47656
PathwayREACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS

ITPR1 ITPR2 ITPR3

4.68e-0613373MM14553
PathwayREACTOME_INTRA_GOLGI_AND_RETROGRADE_GOLGI_TO_ER_TRAFFIC

KIF26B KLC4 TRIP11 KLC3 KIF11 DCTN3

8.83e-06189376MM15356
PathwayREACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS

ITPR1 ITPR2 ITPR3

9.10e-0616373M26945
PathwayREACTOME_INTRA_GOLGI_AND_RETROGRADE_GOLGI_TO_ER_TRAFFIC

KIF26B KLC4 TRIP11 KLC3 KIF11 DCTN3

1.33e-05203376M27654
PathwayREACTOME_KINESINS

KIF26B KLC4 KLC3 KIF11

1.44e-0557374MM15714
PathwayREACTOME_VEGFR2_MEDIATED_CELL_PROLIFERATION

ITPR1 ITPR2 ITPR3

1.57e-0519373M27423
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

1.57e-0519373M47760
PathwayKEGG_MEDICUS_REFERENCE_TCR_PLCG_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

1.57e-0519373M47733
PathwayKEGG_MEDICUS_REFERENCE_MACHR_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

1.84e-0520373M47688
PathwayREACTOME_KINESINS

KIF26B KLC4 KLC3 KIF11

1.88e-0561374M977
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MACHR_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

2.14e-0521373M47689
PathwayREACTOME_GOLGI_TO_ER_RETROGRADE_TRANSPORT

KIF26B KLC4 KLC3 KIF11 DCTN3

2.20e-05131375MM15497
PathwayREACTOME_GOLGI_TO_ER_RETROGRADE_TRANSPORT

KIF26B KLC4 KLC3 KIF11 DCTN3

2.46e-05134375M27751
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

2.48e-0522373M47690
PathwayKEGG_MEDICUS_REFERENCE_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

2.48e-0522373M47675
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

2.84e-0523373M47676
PathwayREACTOME_EFFECTS_OF_PIP2_HYDROLYSIS

ITPR1 ITPR2 ITPR3

3.68e-0525373MM14511
PathwayREACTOME_EFFECTS_OF_PIP2_HYDROLYSIS

ITPR1 ITPR2 ITPR3

4.66e-0527373M12123
PathwayREACTOME_PLATELET_CALCIUM_HOMEOSTASIS

ITPR1 ITPR2 ITPR3

4.66e-0527373MM15053
PathwayREACTOME_PLATELET_CALCIUM_HOMEOSTASIS

ITPR1 ITPR2 ITPR3

5.21e-0528373M924
PathwayREACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION

ITPR1 ITPR2 ITPR3

7.83e-0532373MM14983
PathwaySIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES

ITPR1 ITPR2 ITPR3

1.12e-0436373M1315
PathwayWP_VITAMIN_DSENSITIVE_CALCIUM_SIGNALING_IN_DEPRESSION

ITPR1 ITPR2 ITPR3

1.12e-0436373M39831
PathwayREACTOME_COPI_DEPENDENT_GOLGI_TO_ER_RETROGRADE_TRAFFIC

KIF26B KLC4 KLC3 KIF11

1.22e-0498374MM15352
PathwayREACTOME_COPI_DEPENDENT_GOLGI_TO_ER_RETROGRADE_TRAFFIC

KIF26B KLC4 KLC3 KIF11

1.32e-04100374M27650
PathwayREACTOME_DAG_AND_IP3_SIGNALING

ITPR1 ITPR2 ITPR3

1.66e-0441373M512
PathwayREACTOME_INTEGRATION_OF_ENERGY_METABOLISM

MLXIPL ITPR1 ITPR2 ITPR3

1.77e-04108374M17034
PathwayREACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION

ITPR1 ITPR2 ITPR3

1.78e-0442373M791
PathwayREACTOME_MEMBRANE_TRAFFICKING

ANK3 KIF26B ANKRD28 KLC4 TRIP11 KLC3 KIF11 DCTN3

1.86e-04630378M11480
PathwayWP_RENINANGIOTENSINALDOSTERONE_SYSTEM_RAAS

ITPR1 ITPR2 ITPR3

2.05e-0444373M39845
PathwayKEGG_OOCYTE_MEIOSIS

SLK ITPR1 ITPR2 ITPR3

2.11e-04113374M16817
PathwayREACTOME_VESICLE_MEDIATED_TRANSPORT

KIF26B ANKRD28 KLC4 GOLGA8A TRIP11 KLC3 KIF11 DCTN3

2.18e-04645378MM15232
PathwaySIG_CHEMOTAXIS

ITPR1 ITPR2 ITPR3

2.19e-0445373M5193
PathwayREACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION

KLC4 KLC3 KIF11 DCTN3

2.33e-04116374MM14855
PathwayREACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION

KIF26B KLC4 KLC3 KIF11

2.33e-04116374MM15715
PathwaySIG_BCR_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

2.34e-0446373M8626
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN1_TO_ANTEROGRADE_AXONAL_TRANSPORT

KLC4 KLC3

2.39e-049372M47699
PathwayKEGG_MEDICUS_REFERENCE_GPCR_PLCB_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

3.00e-0450373M47951
PathwayREACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION

KLC4 KLC3 KIF11 DCTN3

3.20e-04126374M705
PathwayREACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_BCR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS

ITPR1 ITPR2 ITPR3

3.56e-0453373MM15716
PathwayREACTOME_RHO_GTPASES_ACTIVATE_KTN1

KLC4 KLC3

3.63e-0411372M27490
PathwayREACTOME_RHO_GTPASES_ACTIVATE_KTN1

KLC4 KLC3

3.63e-0411372MM15218
PathwayREACTOME_ION_HOMEOSTASIS

ITPR1 ITPR2 ITPR3

3.76e-0454373M27460
PathwayREACTOME_ION_HOMEOSTASIS

ITPR1 ITPR2 ITPR3

3.76e-0454373MM15202
PathwayREACTOME_G_PROTEIN_MEDIATED_EVENTS

ITPR1 ITPR2 ITPR3

3.76e-0454373M26911
PathwayKEGG_MEDICUS_REFERENCE_RTK_PLCG_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

3.98e-0455373M47952
PathwayREACTOME_ADAPTIVE_IMMUNE_SYSTEM

KLC4 FBXO30 KLC3 KIF11 DCTN3 ITPR1 ITPR2 ITPR3

4.55e-04719378MM14540
PathwayREACTOME_VESICLE_MEDIATED_TRANSPORT

ANK3 KIF26B ANKRD28 KLC4 TRIP11 KLC3 KIF11 DCTN3

4.81e-04725378M27507
PathwayKEGG_MEDICUS_VARIANT_OLIGOMERIC_CONFORMATION_PRPC_TO_ANTEROGRADE_AXONAL_TRANSPORT

KLC4 KLC3

5.13e-0413372M47763
PathwayREACTOME_REGULATION_OF_INSULIN_SECRETION

ITPR1 ITPR2 ITPR3

5.39e-0461373MM15071
PathwayWP_ALZHEIMERS_DISEASE

KLC4 KLC3 ITPR1 ITPR2 ITPR3

5.62e-04261375M42565
PathwayREACTOME_CA2_PATHWAY

ITPR1 ITPR2 ITPR3

5.66e-0462373M27321
PathwayREACTOME_HEMOSTASIS

KIF26B KLC4 KLC3 KIF11 ITPR1 ITPR2 ITPR3

6.15e-04571377MM14472
PathwayKEGG_LONG_TERM_POTENTIATION

ITPR1 ITPR2 ITPR3

8.07e-0470373M3115
PathwayKEGG_LONG_TERM_DEPRESSION

ITPR1 ITPR2 ITPR3

8.07e-0470373M8232
PathwayREACTOME_INTEGRATION_OF_ENERGY_METABOLISM

ITPR1 ITPR2 ITPR3

8.76e-0472373MM14631
PathwayWP_AFFECTED_PATHWAYS_IN_DUCHENNE_MUSCULAR_DYSTROPHY

ITPR1 ITPR2 ITPR3

9.49e-0474373M48080
PathwayWP_ALZHEIMERS_DISEASE

ITPR1 ITPR2 ITPR3

9.49e-0474373MM15962
PathwayREACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION

KIF26B KLC4 KLC3 KIF11

9.88e-04170374M941
PathwayREACTOME_PLATELET_HOMEOSTASIS

ITPR1 ITPR2 ITPR3

1.03e-0376373MM15051
PathwayKEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM

ITPR1 ITPR2 ITPR3

1.03e-0376373M9052
PathwayREACTOME_REGULATION_OF_INSULIN_SECRETION

ITPR1 ITPR2 ITPR3

1.11e-0378373M1921
PathwayWP_KCNQ2RELATED_EPILEPSIES

ANK3 ITPR1

1.11e-0319372M48320
PathwayREACTOME_ADAPTIVE_IMMUNE_SYSTEM

KLC4 FBXO30 KLC3 KIF11 DCTN3 ITPR1 ITPR2 ITPR3

1.15e-03828378M1058
PathwayREACTOME_ROLE_OF_PHOSPHOLIPIDS_IN_PHAGOCYTOSIS

ITPR1 ITPR2 ITPR3

1.28e-0382373M27110
PathwayREACTOME_FCERI_MEDIATED_CA_2_MOBILIZATION

ITPR1 ITPR2 ITPR3

1.47e-0386373M27206
PathwayREACTOME_PLATELET_HOMEOSTASIS

ITPR1 ITPR2 ITPR3

1.47e-0386373M916
PathwayREACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_BCR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS

ITPR1 ITPR2 ITPR3

1.47e-0386373M601
PathwayWP_ALZHEIMERS_DISEASE_AND_MIRNA_EFFECTS

KLC4 KLC3 ITPR1 ITPR2 ITPR3

1.52e-03326375M39379
PathwayKEGG_GAP_JUNCTION

ITPR1 ITPR2 ITPR3

1.67e-0390373M4013
PathwayREACTOME_OPIOID_SIGNALLING

ITPR1 ITPR2 ITPR3

1.67e-0390373M6467
PathwayREACTOME_HEMOSTASIS

KIF26B KLC4 KLC3 KIF11 ITPR1 ITPR2 ITPR3

1.70e-03679377M8395
PathwayKEGG_MEDICUS_REFERENCE_ANTEROGRADE_AXONAL_TRANSPORT

KLC4 KLC3

1.78e-0324372M47671
PathwayKEGG_MEDICUS_PATHOGEN_SALMONELLA_SIFA_TO_MICROTUBULE_PLUS_END_DIRECTED_TRANSPORT

KLC4 KLC3

1.94e-0325372M47775
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_ANTEROGRADE_AXONAL_TRANSPORT

KLC4 KLC3

1.94e-0325372M47710
PathwayREACTOME_FCGR3A_MEDIATED_IL10_SYNTHESIS

ITPR1 ITPR2 ITPR3

1.95e-0395373M29842
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_ANTEROGRADE_AXONAL_TRANSPORT

KLC4 KLC3

2.09e-0326372M47672
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH9 DCTN3

2.26e-0327372M47755
PathwayREACTOME_CLEC7A_DECTIN_1_SIGNALING

ITPR1 ITPR2 ITPR3

2.26e-03100373M27467
PathwayKEGG_GNRH_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

2.32e-03101373M1979
PathwayREACTOME_CARDIAC_CONDUCTION

ITPR1 ITPR2 ITPR3

2.46e-03103373MM15196
PathwayREACTOME_SIGNALING_BY_VEGF

ITPR1 ITPR2 ITPR3

2.67e-03106373M27077
PathwayKEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION

ITPR1 ITPR2 ITPR3

3.36e-03115373M9387
PathwayKEGG_MEDICUS_REFERENCE_ARL8_REGULATED_MICROTUBULE_PLUS_END_DIRECTED_TRANSPORT

KLC4 KLC3

3.78e-0335372M47774
PathwayREACTOME_CARDIAC_CONDUCTION

ITPR1 ITPR2 ITPR3

4.74e-03130373M27454
PathwayREACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR

ITPR1 ITPR2 ITPR3

4.84e-03131373MM15717
PathwayREACTOME_ANTI_INFLAMMATORY_RESPONSE_FAVOURING_LEISHMANIA_PARASITE_INFECTION

ITPR1 ITPR2 ITPR3

5.15e-03134373M29840
PathwayWP_NUCLEOTIDEBINDING_OLIGOMERIZATION_DOMAIN_NOD_PATHWAY

NAIP NLRP4

5.15e-0341372M39698
PathwayKEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT

DNAH9 DCTN3

5.66e-0343372M47669
PathwayREACTOME_C_TYPE_LECTIN_RECEPTORS_CLRS

ITPR1 ITPR2 ITPR3

5.82e-03140373M27484
PathwayREACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS

ITPR1 ITPR2 ITPR3

6.17e-03143373M27107
Pubmed

Type 3 Inositol 1,4,5-Trisphosphate Receptor is a Crucial Regulator of Calcium Dynamics Mediated by Endoplasmic Reticulum in HEK Cells.

ITPR1 ITPR2 ITPR3

3.34e-09353331979185
Pubmed

Evidence that type I, II, and III inositol 1,4,5-trisphosphate receptors can occur as integral plasma membrane proteins.

ITPR1 ITPR2 ITPR3

3.34e-09353310874040
Pubmed

Expression of inositol 1,4,5-trisphosphate receptors in mouse oocytes and early embryos: the type I isoform is upregulated in oocytes and downregulated after fertilization.

ITPR1 ITPR2 ITPR3

3.34e-0935339808793
Pubmed

Tsg101 regulates PI(4,5)P2/Ca(2+) signaling for HIV-1 Gag assembly.

ITPR1 ITPR2 ITPR3

3.34e-09353324904548
Pubmed

Abnormal distribution of inositol 1,4,5-trisphosphate receptors in human muscle can be related to altered calcium signals and gene expression in Duchenne dystrophy-derived cells.

ITPR1 ITPR2 ITPR3

3.34e-09353320395455
Pubmed

Molecular basis of the isoform-specific ligand-binding affinity of inositol 1,4,5-trisphosphate receptors.

ITPR1 ITPR2 ITPR3

3.34e-09353317327232
Pubmed

Inositol 1,4,5-trisphosphate receptors are autoantibody target antigens in patients with Sjögren's syndrome and other systemic rheumatic diseases.

ITPR1 ITPR2 ITPR3

3.34e-09353317437169
Pubmed

Nuclear inositol 1,4,5-trisphosphate receptors regulate local Ca2+ transients and modulate cAMP response element binding protein phosphorylation.

ITPR1 ITPR2 ITPR3

3.34e-09353316014380
Pubmed

Type 2 and type 3 inositol 1,4,5-trisphosphate (IP3) receptors promote the differentiation of granule cell precursors in the postnatal cerebellum.

ITPR1 ITPR2 ITPR3

3.34e-09353318194433
Pubmed

Knockdown of the type 2 and 3 inositol 1,4,5-trisphosphate receptors suppresses muscarinic antinociception in mice.

ITPR1 ITPR2 ITPR3

3.34e-09353317890015
Pubmed

Decreased olfactory mucus secretion and nasal abnormality in mice lacking type 2 and type 3 IP3 receptors.

ITPR1 ITPR2 ITPR3

3.34e-09353318547250
Pubmed

Inositol 1,4,5-trisphosphate receptor gene variants are related to the risk of breast cancer in a Chinese population.

ITPR1 ITPR2 ITPR3

3.34e-09353336350267
Pubmed

IP3 receptors regulate vascular smooth muscle contractility and hypertension.

ITPR1 ITPR2 ITPR3

3.34e-09353327777977
Pubmed

The versatility and universality of calcium signalling.

ITPR1 ITPR2 ITPR3

3.34e-09353311413485
Pubmed

Inositol 1, 4, 5-trisphosphate receptors and human left ventricular myocytes.

ITPR1 ITPR2 ITPR3

3.34e-09353323983250
Pubmed

Differential distribution of inositol trisphosphate receptor isoforms in mouse oocytes.

ITPR1 ITPR2 ITPR3

3.34e-0935339858485
Pubmed

Using concatenated subunits to investigate the functional consequences of heterotetrameric inositol 1,4,5-trisphosphate receptors.

ITPR1 ITPR2 ITPR3

3.34e-09353326009177
Pubmed

Differential inositol 1,4,5-trisphosphate receptor signaling in a neuronal cell line.

ITPR1 ITPR2 ITPR3

3.34e-09353317581770
Pubmed

Activation of the inositol (1,4,5)-triphosphate calcium gate receptor is required for HIV-1 Gag release.

ITPR1 ITPR2 ITPR3

3.34e-09353320427533
Pubmed

Predominant role of type 1 IP3 receptor in aortic vascular muscle contraction.

ITPR1 ITPR2 ITPR3

3.34e-09353318241669
Pubmed

Receptor-activated single channels in intact human platelets.

ITPR1 ITPR2 ITPR3

3.34e-0935331693919
Pubmed

Granulosa cells express three inositol 1,4,5-trisphosphate receptor isoforms: cytoplasmic and nuclear Ca2+ mobilization.

ITPR1 ITPR2 ITPR3

3.34e-09353319068129
Pubmed

Functional inositol 1,4,5-trisphosphate receptors assembled from concatenated homo- and heteromeric subunits.

ITPR1 ITPR2 ITPR3

3.34e-09353323955339
Pubmed

Loss of IP3R-dependent Ca2+ signalling in thymocytes leads to aberrant development and acute lymphoblastic leukemia.

ITPR1 ITPR2 ITPR3

1.34e-08453325215520
Pubmed

Inositol 1, 4, 5-trisphosphate receptor interacts with the SNARE domain of syntaxin 1B.

ITPR1 ITPR2 ITPR3

1.34e-08453321424589
Pubmed

IP3R-mediated Ca2+ signals govern hematopoietic and cardiac divergence of Flk1+ cells via the calcineurin-NFATc3-Etv2 pathway.

ITPR1 ITPR2 ITPR3

1.34e-08453328419336
Pubmed

Alternative splice variants of hTrp4 differentially interact with the C-terminal portion of the inositol 1,4,5-trisphosphate receptors.

ITPR1 ITPR2 ITPR3

1.34e-08453311163362
Pubmed

IP3R-mediated Ca2+ signaling controls B cell proliferation through metabolic reprogramming.

ITPR1 ITPR2 ITPR3

1.34e-08453335494252
Pubmed

Loss of IP3 Receptor-Mediated Ca2+ Release in Mouse B Cells Results in Abnormal B Cell Development and Function.

ITPR1 ITPR2 ITPR3

1.34e-08453328615414
Pubmed

Distinct localization and function of (1,4,5)IP(3) receptor subtypes and the (1,3,4,5)IP(4) receptor GAP1(IP4BP) in highly purified human platelet membranes.

ITPR1 ITPR2 ITPR3

1.34e-08453310828023
Pubmed

InsP₃receptors and Orai channels in pancreatic acinar cells: co-localization and its consequences.

ITPR1 ITPR2 ITPR3

3.33e-08553321568942
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

ANK3 SND1 NEK5 NEK8 TTC21A CCDC150 ANKRD28 EEA1 KLC4 TRIP11 FBXO30 KLC3 DCTN3

6.59e-081321531327173435
Pubmed

Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.

ITPR1 ITPR2 ITPR3

6.66e-08653323463619
Pubmed

Sprouty2 regulates PI(4,5)P2/Ca2+ signaling and HIV-1 Gag release.

ITPR1 ITPR2 ITPR3

6.66e-08653321762810
Pubmed

IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.

ITPR1 ITPR2 ITPR3

6.66e-08653316844763
Pubmed

A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.

ITPR1 ITPR2 ITPR3

6.66e-08653320519450
Pubmed

Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.

ITPR1 ITPR2 ITPR3

6.66e-08653325966694
Pubmed

Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.

ITPR1 ITPR2 ITPR3

1.16e-07753311860456
Pubmed

Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes.

ITPR1 ITPR2 ITPR3

1.16e-07753322495310
Pubmed

Ca2+ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+ uniporter gene MCU.

ITPR1 ITPR2 ITPR3

2.79e-07953325737585
Pubmed

Type 1 and 3 inositol trisphosphate receptors are required for extra-embryonic vascular development.

ITPR1 ITPR2 ITPR3

5.47e-071153327514653
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

MLXIPL HIVEP1 KIF26B OSBPL10 EDC4 KLC4 TRIP11 LYST KLC3 KIF11

6.11e-07861531036931259
Pubmed

Evidence That ITPR2-Mediated Intracellular Calcium Release in Oligodendrocytes Regulates the Development of Carbonic Anhydrase II + Type I/II Oligodendrocytes and the Sizes of Myelin Fibers.

ITPR1 ITPR2 ITPR3

1.20e-061453334630045
Pubmed

Synergistic Signaling by Light and Acetylcholine in Mouse Iris Sphincter Muscle.

ITPR1 ITPR2 ITPR3

1.50e-061553328578927
Pubmed

Isoform diversity of the inositol trisphosphate receptor in cell types of mouse origin.

ITPR2 ITPR3

2.28e-0625329065779
Pubmed

Expression of IP3 receptor isoforms at the nodes of Ranvier in rat sciatic nerve.

ITPR2 ITPR3

2.28e-06253217496801
Pubmed

IP3 receptor types 2 and 3 mediate exocrine secretion underlying energy metabolism.

ITPR2 ITPR3

2.28e-06253216195467
Pubmed

Mutational analysis of the ligand binding site of the inositol 1,4,5-trisphosphate receptor.

ITPR1 ITPR3

2.28e-0625328663526
Pubmed

The Pro335 --> Leu polymorphism of type 3 inositol 1,4,5-trisphosphate receptor found in mouse inbred lines results in functional change.

ITPR1 ITPR3

2.28e-06253215890645
Pubmed

Mice lacking inositol 1,4,5-trisphosphate receptors exhibit dry eye.

ITPR2 ITPR3

2.28e-06253224901844
Pubmed

Fbxo30 Regulates Mammopoiesis by Targeting the Bipolar Mitotic Kinesin Eg5.

FBXO30 KIF11

2.28e-06253227117404
Pubmed

Molecular cloning of mouse type 2 and type 3 inositol 1,4,5-trisphosphate receptors and identification of a novel type 2 receptor splice variant.

ITPR2 ITPR3

2.28e-06253215632133
Pubmed

Adrenergic inhibition facilitates normalization of extracellular potassium after cortical spreading depolarization.

ITPR2 ITPR3

2.28e-06253233854148
Pubmed

Tyr-167/Trp-168 in type 1/3 inositol 1,4,5-trisphosphate receptor mediates functional coupling between ligand binding and channel opening.

ITPR1 ITPR3

2.28e-06253220813840
Pubmed

Inositol (1,4,5)-trisphosphate receptor links to filamentous actin are important for generating local Ca2+ signals in pancreatic acinar cells.

ITPR2 ITPR3

2.28e-06253215713744
Pubmed

Heteroligomers of type-I and type-III inositol trisphosphate receptors in WB rat liver epithelial cells.

ITPR1 ITPR3

2.28e-0625327559486
Pubmed

Structural studies of inositol 1,4,5-trisphosphate receptor: coupling ligand binding to channel gating.

ITPR1 ITPR3

2.28e-06253220843799
Pubmed

Type 1 and 2 IP3 receptors respond differently to catecholamines and stress.

ITPR1 ITPR2

2.28e-06253219120126
Pubmed

An antidepressant behaviour in mice carrying a gene-specific InsP3R1, InsP3R2 and InsP3R3 protein knockdown.

ITPR1 ITPR2

2.28e-06253218708078
Pubmed

Immunolocalization of type 2 inositol 1,4,5-trisphosphate receptors in cardiac myocytes from newborn mice.

ITPR1 ITPR2

2.28e-06253215201137
Pubmed

Pancreatic protease activation by alcohol metabolite depends on Ca2+ release via acid store IP3 receptors.

ITPR2 ITPR3

2.28e-06253219528657
Pubmed

Determination of relative amounts of inositol trisphosphate receptor mRNA isoforms by ratio polymerase chain reaction.

ITPR2 ITPR3

2.28e-0625328063813
Pubmed

Cloning and characterization of human type 2 and type 3 inositol 1,4,5-trisphosphate receptors.

ITPR2 ITPR3

2.28e-0625328081734
Pubmed

Sulphide signalling potentiates apoptosis through the up-regulation of IP3 receptor types 1 and 2.

ITPR1 ITPR2

2.28e-06253223582047
Pubmed

Three additional inositol 1,4,5-trisphosphate receptors: molecular cloning and differential localization in brain and peripheral tissues.

ITPR1 ITPR3

2.28e-0625321374893
Pubmed

Distinct roles of inositol 1,4,5-trisphosphate receptor types 1 and 3 in Ca2+ signaling.

ITPR1 ITPR3

2.28e-06253214707143
Pubmed

The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity.

ITPR1 ITPR2 ITPR3

5.04e-062253311696558
Pubmed

Release of calcium from inositol 1,4,5-trisphosphate receptor-regulated stores by HIV-1 Tat regulates TNF-alpha production in human macrophages.

ITPR1 ITPR2 ITPR3

6.61e-062453310843712
Pubmed

Rescue of calcineurin Aα(-/-) mice reveals a novel role for the α isoform in the salivary gland.

ITPR2 ITPR3

6.83e-06353221435446
Pubmed

Ubiquitination and proteasomal degradation of endogenous and exogenous inositol 1,4,5-trisphosphate receptors in alpha T3-1 anterior pituitary cells.

ITPR1 ITPR3

6.83e-06353212421829
Pubmed

Identification of KRAP-expressing cells and the functional relevance of KRAP to the subcellular localization of IP3R in the stomach and kidney.

ITPR1 ITPR3

6.83e-06353222992961
Pubmed

Type 1 inositol (1,4,5)-trisphosphate receptor activates ryanodine receptor 1 to mediate calcium spark signaling in adult mammalian skeletal muscle.

ITPR1 ITPR2

6.83e-06353223223241
Pubmed

Identification of a family of calcium sensors as protein ligands of inositol trisphosphate receptor Ca(2+) release channels.

ITPR1 ITPR3

6.83e-06353212032348
Pubmed

Phosphorylation of inositol 1,4,5-trisphosphate receptors by protein kinase B/Akt inhibits Ca2+ release and apoptosis.

ITPR1 ITPR3

6.83e-06353218250332
Pubmed

Inositol 1,4,5-trisphosphate receptors are essential for fetal-maternal connection and embryo viability.

ITPR1 ITPR2

6.83e-06353232320395
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

MLXIPL SLK ANK3 SND1 SYNE1 TTC21A OSBPL10 ZNFX1 EDC4 TRIP11 ITPR2

8.54e-061431531137142655
Pubmed

Atm deficiency in the DNA polymerase β null cerebellum results in cerebellar ataxia and Itpr1 reduction associated with alteration of cytosine methylation.

ITPR1 ITPR2 ITPR3

1.19e-052953332123907
Pubmed

Regulation of InsP3 receptor activity by neuronal Ca2+-binding proteins.

ITPR1 ITPR3

1.36e-05453214685260
Pubmed

Abnormal taste perception in mice lacking the type 3 inositol 1,4,5-trisphosphate receptor.

ITPR2 ITPR3

1.36e-05453217925404
Pubmed

IAPs: more than just inhibitors of apoptosis proteins.

NAIP BIRC6

1.36e-05453218414036
Pubmed

Ins(1,4,5)P3 receptor-mediated Ca2+ signaling and autophagy induction are interrelated.

ITPR1 ITPR3

1.36e-05453222082873
Pubmed

Selective regulation of IP3-receptor-mediated Ca2+ signaling and apoptosis by the BH4 domain of Bcl-2 versus Bcl-Xl.

ITPR1 ITPR2

1.36e-05453221818117
Pubmed

IRE1α/XBP1-mediated branch of the unfolded protein response regulates osteoclastogenesis.

ITPR2 ITPR3

1.36e-05453226193638
Pubmed

Hypoxia differently modulates gene expression of inositol 1,4,5-trisphosphate receptors in mouse kidney and HEK 293 cell line.

ITPR1 ITPR2

1.36e-05453219120137
Pubmed

A combination of SILAC and nucleotide acyl phosphate labelling reveals unexpected targets of the Rsk inhibitor BI-D1870.

SLK MST1L

1.36e-05453227919044
Pubmed

Stabilization of cortical actin induces internalization of transient receptor potential 3 (Trp3)-associated caveolar Ca2+ signaling complex and loss of Ca2+ influx without disruption of Trp3-inositol trisphosphate receptor association.

ITPR1 ITPR3

1.36e-05453211524429
Pubmed

The Bcl-2 protein family member Bok binds to the coupling domain of inositol 1,4,5-trisphosphate receptors and protects them from proteolytic cleavage.

ITPR1 ITPR3

1.36e-05453223884412
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

SLK ANK3 SYNE1 ANKRD28 ZNFX1 EDC4 GOLGA8A TRIP11 KIF11

1.37e-0596353928671696
Pubmed

BANK regulates BCR-induced calcium mobilization by promoting tyrosine phosphorylation of IP(3) receptor.

ITPR1 ITPR2

2.27e-05553211782428
Pubmed

The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor.

ITPR1 ITPR3

2.27e-05553219706527
Pubmed

Widespread expression of inositol 1,4,5-trisphosphate receptor type 1 gene (Insp3r1) in the mouse central nervous system.

ITPR1 ITPR3

2.27e-0555328081710
Pubmed

Calmodulin protects against alcohol-induced pancreatic trypsinogen activation elicited via Ca2+ release through IP3 receptors.

ITPR2 ITPR3

2.27e-05553221436055
Pubmed

Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum.

ITPR1 ITPR3

2.27e-05553215613488
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

ITPR1 ITPR2 ITPR3

2.71e-053853330786075
Pubmed

Genetic evidence supporting caveolae microdomain regulation of calcium entry in endothelial cells.

ITPR1 ITPR3

3.40e-05653217416589
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

SLK SND1 KIF26B USP1 KIF11

4.47e-0525653533397691
Pubmed

The inhibitors of apoptosis (IAPs) and their emerging role in cancer.

NAIP BIRC6

4.76e-0575329916987
Pubmed

IAP family proteins--suppressors of apoptosis.

NAIP BIRC6

4.76e-0575329990849
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

SLK REXO4 HIVEP1 SND1 SYNE1 EEA1 GALNT5 EDC4 MED23 KIF11

5.04e-051425531030948266
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

SND1 ASCC2 MED23 ITPR1 ITPR2 ITPR3

5.50e-0544053634244565
InteractionIRAG1 interactions

ITPR1 ITPR2 ITPR3

5.45e-0614513int:IRAG1
InteractionTESPA1 interactions

ITPR1 ITPR2 ITPR3

8.35e-0616513int:TESPA1
InteractionTRPC4 interactions

ITPR1 ITPR2 ITPR3

2.61e-0523513int:TRPC4
InteractionRASEF interactions

ITPR1 ITPR2 ITPR3

3.38e-0525513int:RASEF
InteractionBBOX1 interactions

ITPR1 ITPR2 ITPR3

5.33e-0529513int:BBOX1
InteractionTRPC1 interactions

ITPR1 ITPR2 ITPR3

5.33e-0529513int:TRPC1
InteractionSGF29 interactions

EDC4 CLHC1 ITPR1 ITPR2 ITPR3

5.83e-05164515int:SGF29
InteractionTRPC2 interactions

ITPR1 ITPR3

6.25e-055512int:TRPC2
InteractionINSYN1 interactions

KLC4 BIRC6 TRIP11 KIF11 DCTN3

6.72e-05169515int:INSYN1
InteractionVCL interactions

SLK ASCC2 EDC4 BIRC6 FBXO30 KIF11

1.16e-04305516int:VCL
InteractionC2orf69 interactions

KLC3 KIF11

1.31e-047512int:C2orf69
InteractionCHRNA3 interactions

KLC3 ITPR2 ITPR3

1.31e-0439513int:CHRNA3
InteractionSSR1 interactions

SND1 SYNE1 NEK8 MED23 ITPR1 ITPR2 ITPR3

1.36e-04453517int:SSR1
Cytoband12p13

KLRF2 CCND2

2.52e-036453212p13
GeneFamilyInositol 1,4,5-triphosphate receptors|Protein phosphatase 1 regulatory subunits

ITPR1 ITPR2 ITPR3

8.57e-093383297
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

TTC21A KLC4 KLC3 CFAP46

9.70e-05115384769
GeneFamilyRing finger proteins|Baculoviral IAP repeat containing|Caspase recruitment domain containing

NAIP BIRC6

1.19e-048382419
GeneFamilyNLR family

NAIP NLRP4

1.25e-0325382666
GeneFamilyKinesins|Pleckstrin homology domain containing

KIF26B KIF11

4.20e-0346382622
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

ANKRD28 ITPR1 ITPR3

6.44e-03181383694
ToppCellEpithelial-Epithelial-D_(Ciliated)|Epithelial / shred on cell class and cell subclass (v4)

CCDC30 NEK5 SYNE1 TTC21A DNAH9 CFAP46

9.58e-081885368f30535a32968a81a304315a49c0d90a77d36948
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ANK3 CCDC30 NEK5 TTC21A DNAH9 CFAP46

1.12e-07193536ea345d34440b25f65358a53dc72831998d1c3620
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC30 NEK5 SYNE1 TTC21A DNAH9 CFAP46

1.26e-0719753674a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellBronchus_Control_(B.)-Epithelial-TX-Ciliated|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

CCDC30 NEK5 SYNE1 TTC21A DNAH9 CFAP46

1.38e-072005366a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC30 NEK5 TTC21A DNAH9 CFAP46

1.75e-06169535fba841664939c771881ba97f14ef1df6635c04ff
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC30 NEK5 TTC21A DNAH9 CFAP46

1.75e-0616953514aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NFE2L3 CCDC30 NEK5 CFAP46 CCND2

1.85e-061715354f2a83d8091f1fd29542d2e5add57fd482e921b5
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC30 NEK5 TTC21A CLHC1 CFAP46

2.38e-0618053592fb01b91261b3103454924cde56add337b41844
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GOT1L1 NEK5 TTC21A DNAH9 CFAP46

2.51e-06182535587636c0f127231de21acd8aa632b74ff22ca8c2
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GOT1L1 NEK5 TTC21A DNAH9 CFAP46

2.51e-06182535adfadd7893e74b3002f13f00875e3667d3493e0c
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 NEK5 TTC21A DNAH9 CFAP46

2.65e-06184535797b6a6d6f6aafae98f75ca8bffe8263f8d3ff9b
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 NEK5 TTC21A DNAH9 CFAP46

2.65e-0618453577d5b60a20b277f589b18f7a131142a7ef2dac17
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CCDC30 NEK5 TTC21A DNAH9 CFAP46

2.72e-061855355e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 NEK5 TTC21A DNAH9 CFAP46

3.02e-06189535057d7a03fdbe779122b203619a6f947f49b84d28
ToppCelldroplet-Lung-immune-endo-depleted-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC30 NEK5 TTC21A DNAH9 CFAP46

3.02e-0618953528c750ac56e3861fe7280e32839a4d8ce8bd8692
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 NEK5 TTC21A DNAH9 CFAP46

3.02e-0618953502c6128a9ab5818e0881dcadafdad5f08b9a67cf
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 NEK5 TTC21A DNAH9 CFAP46

3.02e-06189535164ea92ff6a1aa2ead1c9b8f64f99a9d65437232
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 NEK5 TTC21A DNAH9 CFAP46

3.02e-061895359f57a131902d23494bf389baf6e6e2d99f88b2c8
ToppCelldroplet-Lung-immune-endo-depleted-3m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC30 NEK5 TTC21A DNAH9 CFAP46

3.02e-06189535efee01edd171bf569267b672fab05c421de6c92d
ToppCellPND10-Epithelial-Epithelial_Airway|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 NEK5 TTC21A DNAH9 CFAP46

3.02e-06189535407d8a59969d83f014600aae1a55092283a13970
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 NEK5 TTC21A DNAH9 CFAP46

3.02e-06189535a85099bd598a27ee64ee0664d051d89fa8d62fc9
ToppCellEpithelial-D_(Ciliated)|World / shred on cell class and cell subclass (v4)

CCDC30 NEK5 TTC21A DNAH9 CFAP46

3.02e-061895350bf560b595c7a8450a46bc821b742b67965bd9f9
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 NEK5 TTC21A DNAH9 CFAP46

3.02e-06189535e443b02502edaefa94567a9e8af5756e8e11ff30
ToppCellNasal_Brush-Epithelial-Ciliated_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

CCDC30 NEK5 SYNE1 DNAH9 CFAP46

3.10e-061905359ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCellE18.5-Epithelial-Epithelial_Airway|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 NEK5 TTC21A CFAP46 CCND2

3.10e-061905355c012935ea5e35a2d0d08ea7dc04ffbe3c2a10ac
ToppCellNasal_Brush-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

CCDC30 NEK5 SYNE1 DNAH9 CFAP46

3.10e-06190535833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 NEK5 TTC21A DNAH9 CFAP46

3.18e-06191535acd844b477a069b2dcf07b2998e1b5c87dc0eb94
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 NEK5 TTC21A DNAH9 CFAP46

3.18e-06191535bda8faf92495c8b362850c0aff4fc6fbdd9c563b
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 NEK5 TTC21A DNAH9 CFAP46

3.18e-061915356880fb348bb0915db9a5da4f3566ca9ff93ed258
ToppCellCiliated-cil-3|World / Class top

CCDC30 NEK5 SYNE1 TTC21A DNAH9

3.26e-061925354989ebb8812b8af1870599acd932849122c05a29
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

CCDC30 NEK5 SYNE1 DNAH9 CFAP46

3.26e-06192535be592e661367affced9ebe80849b466e6adb3a34
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 NEK5 TTC21A DNAH9 CFAP46

3.26e-06192535b5cdc2dae3154b1e4ade88f841f38584402ffe33
ToppCellPND03-Epithelial-Epithelial_Airway|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 NEK5 TTC21A DNAH9 CFAP46

3.26e-061925352d8d5a38e205339eda9c8aca1ca9ba3dcbe5ae56
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

CCDC30 NEK5 SYNE1 DNAH9 CFAP46

3.35e-061935350b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

CCDC30 NEK5 SYNE1 DNAH9 CFAP46

3.35e-06193535ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

CCDC30 NEK5 SYNE1 DNAH9 CFAP46

3.43e-061945357a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC30 SYNE1 TTC21A DNAH9 CFAP46

3.43e-061945354a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

CCDC30 NEK5 SYNE1 DNAH9 CFAP46

3.43e-06194535b4ce60c06568123008b1081d644733cb91c28f51
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

ANK3 NEK5 SYNE1 DNAH9 CFAP46

3.52e-06195535fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC30 NEK5 TTC21A DNAH9 CFAP46

3.52e-06195535649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

ANK3 NEK5 SYNE1 DNAH9 CFAP46

3.52e-06195535eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC30 NEK5 TTC21A DNAH9 CFAP46

3.52e-06195535129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC30 NEK5 TTC21A DNAH9 CFAP46

3.52e-061955353e70ee987d66d450062d5df3d7c733ccc7344470
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CCDC30 SYNE1 TTC21A DNAH9 CFAP46

3.52e-061955353486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CCDC30 SYNE1 TTC21A DNAH9 CFAP46

3.61e-06196535d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC30 NEK5 SYNE1 DNAH9 CFAP46

3.70e-0619753587db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCellPSB-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CCDC30 NEK5 SYNE1 DNAH9 CFAP46

3.70e-061975356865f4831eb23794fb88a8649d48d497bbae3f44
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC30 NEK5 SYNE1 DNAH9 CFAP46

3.70e-0619753591637bdeab85024b5a02d1066f76cb803a2d6420
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CCDC30 SYNE1 TTC21A DNAH9 CFAP46

3.70e-0619753571fea4aa6ce96c7693fa94792d08770622873850
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC30 NEK5 SYNE1 DNAH9 CFAP46

3.70e-0619753522c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC30 NEK5 SYNE1 DNAH9 CFAP46

3.70e-061975353bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CCDC30 SYNE1 TTC21A DNAH9 CFAP46

3.70e-06197535d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CCDC30 SYNE1 TTC21A DNAH9 CFAP46

3.70e-06197535e453d085182364ca347cbcc9dc995c62c3353016
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC30 NEK5 TTC21A DNAH9 CFAP46

3.98e-06200535cc906ff02fd335ff633b3b97afceb670494f910a
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC30 NEK5 TTC21A DNAH9 CFAP46

3.98e-0620053579e59ab31d3d3385b1b072dc75508af9546c2e1b
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CCDC30 NEK5 TTC21A DNAH9 CFAP46

3.98e-06200535ddd39b754bfaa98249d497dfb7e97ec58617a11a
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC30 NEK5 TTC21A DNAH9 CFAP46

3.98e-06200535873def69bf55ccbfc944bc10c5afc06be019c312
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CCDC30 NEK5 TTC21A DNAH9 CFAP46

3.98e-0620053531d75c26055177d656df1fbb10b764cebd61e122
ToppCellParenchyma_Control_(B.)-Epithelial-TX-Ciliated|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

CCDC30 NEK5 TTC21A DNAH9 CFAP46

3.98e-06200535a521cf837cadf280505ff9d7e641a205af7d6513
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CCDC30 NEK5 TTC21A DNAH9 CFAP46

3.98e-06200535918b576fd9491d23c2bb9d663fa5fb3505cb1c7e
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CCDC30 NEK5 TTC21A DNAH9 CFAP46

3.98e-06200535e1dce91c6c531bb212002a14705e496d77ad3490
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NEK5 KLC4 KLC3 KIF11

1.64e-051285342cf0384240a4a663869cf6b27d954236f6214a9a
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MLXIPL NAIP XKR4 ITPR2

3.06e-051505346c39e73a0b05d4b26589f333ce13924e3d373b8d
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HIVEP1 NEK8 KLRF2 NLRP4

5.10e-051715344fd2c7977c512c51507f055fc74b111c0228ed8b
ToppCelldroplet-Fat-Gat-18m-Epithelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GOT1L1 NEK5 CCDC150 DNAH9

5.34e-05173534a40a52d8041d45dc3bef74fe55945ae07aa018d6
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GOT1L1 CCDC30 NEK5 CLHC1

5.34e-05173534a7cc63bb3ab41feb9e4072700d44dbbbc62c47c6
ToppCelldroplet-Fat-Gat-18m-Epithelial-epithelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GOT1L1 NEK5 CCDC150 DNAH9

5.34e-05173534f0b4dd1cf41d6ee6abb0e1968b8b39f4fabebcb5
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GOT1L1 CCDC30 NEK5 CLHC1

5.34e-05173534e3e3a67a5a93ef4475224a256d45ae24526383cc
ToppCelldroplet-Fat-Gat-18m-Epithelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GOT1L1 NEK5 CCDC150 DNAH9

5.34e-05173534f3f67531f72d6d52e19c7f1f2db1ab4026fb70da
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma|PND07-28-samps / Age Group, Lineage, Cell class and subclass

NEK5 TTC21A DNAH9 CFAP46

5.46e-05174534f41d05a3703d7092bd3c4a97c15ae13069aaa4ad
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NFE2L3 CCDC30 CLHC1 CFAP46

5.46e-05174534179a52d77899a929396b98d4ab2c270dd2ec708e
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NFE2L3 CCDC30 CLHC1 CFAP46

5.46e-051745349165a1094d345328e58962f4b2a20334c3e93ead
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar|PND07-28-samps / Age Group, Lineage, Cell class and subclass

NEK5 TTC21A DNAH9 CFAP46

5.58e-05175534c01a15b2084da4a18f8ff3623f44eb9dfe499f10
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NEK5 TTC21A DNAH9 CFAP46

5.96e-051785343b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCellT_cells-ISG-high_CD4+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

ANK3 TTC21A ZNFX1 DNAH9

6.09e-05179534af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCellCOVID-19-kidney-Epi_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

KIF26B SYNE1 OSBPL10 CCND2

6.09e-05179534e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TTC21A DNAH9 CLHC1 CFAP46

6.09e-051795345e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCellCiliated_cells-B-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

CCDC30 NEK5 DNAH9 CFAP46

6.23e-05180534bdea5ec6b60fc8c7cce4d71db5da74ac8675e211
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC30 NEK5 DNAH9 CFAP46

6.23e-051805341f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KIF26B SYNE1 OSBPL10 XKR4

6.36e-051815345f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KIF26B SYNE1 OSBPL10 XKR4

6.36e-05181534c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

CCDC30 NEK5 DNAH9 CFAP46

6.50e-05182534fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellChildren_(3_yrs)-Immune-enucleated_erythrocyte-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

MLXIPL KIF26B CCDC150 GOLGA8A

6.50e-051825343fddadb2ff75013ec6eeb415872667a6bae1da2d
ToppCellCiliated_cells-B-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

CCDC30 NEK5 DNAH9 CFAP46

6.50e-05182534e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

CCDC30 NEK5 DNAH9 CFAP46

6.92e-0518553430f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NEK8 MED23 USP1 ITPR3

6.92e-0518553487151ab95530e70d61328b336518df58db584acb
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF26B SYNE1 OSBPL10 XKR4

6.92e-0518553434fcfd635c828dad9643bbf1c908d79282d6f5d9
ToppCellCiliated_cells-B-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CCDC30 NEK5 DNAH9 CFAP46

6.92e-05185534f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF26B SYNE1 OSBPL10 XKR4

6.92e-051855348816f2909ed11833ff3d0ed96b9cb6d6fe9e1578
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CCDC30 NEK5 DNAH9 CFAP46

7.07e-0518653476033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellNS-moderate-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CCDC30 NEK5 DNAH9 CFAP46

7.07e-0518653485787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC30 NEK5 DNAH9 CFAP46

7.07e-0518653402fbb02c495e7d64c4ab50e42e5197782f2c0816
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC30 SYNE1 OSBPL10 XKR4

7.07e-05186534f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellPND14-Epithelial-Epithelial_Airway|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 NEK5 TTC21A DNAH9

7.22e-051875341399c703505211c510b3f14c7a2aa9930566c473
ToppCellhuman_hepatoblastoma-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

MLXIPL PRODH2 LYST ITPR2

7.22e-05187534f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCellCiliated_cells-B-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

NEK5 TTC21A DNAH9 CFAP46

7.37e-05188534606907c865bd2f11bb6474932716550f7723d858
ToppCell(7)_Epithelial_cells-(7)_Epithelial-F_(Ciliated)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

NEK5 TTC21A DNAH9 CFAP46

7.37e-051885345ba5cbb403518026e9040379fb5d99339ea977d8
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 NEK5 TTC21A DNAH9

7.52e-05189534b55de812043b670cbde810d7d42f45909b6d66ef
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

NEK5 TTC21A DNAH9 CFAP46

7.52e-05189534a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

CCDC30 NEK5 DNAH9 CFAP46

7.52e-05189534dc440015949a768188c67661b6be63b1ead1a0f0
Drugadenophostin A

ITPR2 ITPR3

5.12e-062522ctd:C085029
DrugIsocaffeine

ITPR1 ITPR3

5.12e-062522CID000001326
Drugadenophostin B

ITPR1 ITPR3

5.12e-062522CID000656722
Drugbenzene 1,2,4-trisphosphate

ITPR1 ITPR3

5.12e-062522CID000192376
Drug5-deoxy-5-fluoro-myo-inositol

ITPR1 ITPR3

1.53e-053522CID000195110
DrugCHEBI:697555

ITPR1 ITPR3

3.06e-054522CID009578246
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

ITPR1 ITPR2 ITPR3

1.19e-0612533DOID:1441 (implicated_via_orthology)
DiseaseAnoxic Encephalopathy

ITPR1 ITPR2

3.17e-062532C0003132
DiseaseBrain Hypoxia

ITPR1 ITPR2

3.17e-062532C1527348
DiseaseAnoxia of brain

ITPR1 ITPR2

3.17e-062532C0995195
DiseaseHypoxic Brain Damage

ITPR1 ITPR2

3.17e-062532C1140716
DiseaseAlzheimer's disease 1 (implicated_via_orthology)

KLC4 KLC3

6.61e-057532DOID:0080348 (implicated_via_orthology)
DiseaseSpastic Paraplegia

KLC4 LYST

1.13e-049532C0037772
Diseasecoffee consumption measurement

MLXIPL SND1 FES BIRC6

3.24e-04182534EFO_0006781
Diseasebirth weight, parental genotype effect measurement

SND1 FES ITPR2 CCND2

3.97e-04192534EFO_0004344, EFO_0005939
Diseaseage at onset, smoking initiation

JOSD2 ITPR2

5.31e-0419532EFO_0004847, EFO_0005670
Diseasediet measurement

MLXIPL RPAP1 ANK3 SND1 KIF26B ASCC2 EEA1 ITPR1

5.32e-041049538EFO_0008111
Diseasevery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio

NFE2L3 MLXIPL USP1 CCND2

6.84e-04222534EFO_0008317, EFO_0020943
Diseaseperiodontitis

MLXIPL CRACR2A OSBPL10 CCND2

6.96e-04223534EFO_0000649
Diseasebirth weight

MLXIPL SND1 FES ITPR2 CCND2

7.42e-04399535EFO_0004344
Diseasevery low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

NFE2L3 MLXIPL USP1 CCND2

9.00e-04239534EFO_0008317, EFO_0020945
DiseaseDrug habituation

SLK SYNE1 XKR4

1.17e-03115533C0013170
DiseaseSubstance-Related Disorders

SLK SYNE1 XKR4

1.17e-03115533C0236969
DiseaseDrug abuse

SLK SYNE1 XKR4

1.17e-03115533C0013146
DiseaseDrug Use Disorders

SLK SYNE1 XKR4

1.17e-03115533C0013222
DiseaseDrug Dependence

SLK SYNE1 XKR4

1.17e-03115533C1510472
DiseaseSubstance Dependence

SLK SYNE1 XKR4

1.17e-03115533C0038580
DiseaseSubstance Use Disorders

SLK SYNE1 XKR4

1.17e-03115533C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

SLK SYNE1 XKR4

1.17e-03115533C0029231
DiseasePrescription Drug Abuse

SLK SYNE1 XKR4

1.17e-03115533C4316881
DiseaseSubstance abuse problem

SLK SYNE1 XKR4

1.20e-03116533C0740858
Diseasebipolar disorder (is_implicated_in)

ANK3 SYNE1

1.25e-0329532DOID:3312 (is_implicated_in)
Diseasecholesterol:total lipids ratio, intermediate density lipoprotein measurement

NFE2L3 MLXIPL USP1

1.36e-03121533EFO_0008595, EFO_0020943
Diseasetriglycerides:total lipids ratio, intermediate density lipoprotein measurement

NFE2L3 MLXIPL USP1

1.56e-03127533EFO_0008595, EFO_0020947

Protein segments in the cluster

PeptideGeneStartEntry
VAKLIIQQCQQLHCL

NAIP

1251

Q13075
DCIQLQLQLNLAHNA

BIRC6

1976

Q9NR09
VNNQQLLCVLSQLEG

GOT1L1

266

Q8NHS2
ILQVFSNILQHCGLQ

ASCC2

201

Q9H1I8
VECLQLLLSHNAQVN

ANKRD28

836

O15084
SQLAALLQLQHQLRC

CFAP46

2111

Q8IYW2
QQLESLQQEACKLHQ

CRACR2A

331

Q9BSW2
NLQVSCLNAEQNQHL

PRODH2

276

Q9UF12
CQAQQAHILQLLQQG

EDC4

1261

Q6P2E9
QLLCENHNRELQNFL

ITPR2

1926

Q14571
FLQLLCENHNRDLQN

ITPR3

1876

Q14573
CQEQIEAVLLNSLQQ

CCND2

246

P30279
VAKQLNNLALLCQNQ

KLC4

336

Q9NSK0
LQLLCENHNRDLQNF

ITPR1

1981

Q14643
ALLNVISNQECNIKH

MST1L

626

Q2TV78
ILCNNLHELQENTIC

KIF11

681

P52732
ICATHLNQLKQEAIQ

KIF26B

186

Q2KJY2
LELCAVHALNNVLQQ

JOSD2

21

Q8TAC2
GNNLQQLVLKICQAH

NEK5

206

Q6P3R8
QDVNLHEAILLCPNN

NFE2L3

311

Q9Y4A8
AAVAQTNQNQLHLCV

MED23

631

Q9ULK4
QAAQNECQVLKLLNH

NEK8

46

Q86SG6
DVAKQLNNLALLCQN

KLC3

331

Q6P597
FQLSQEIKQQIHQCL

NLRP4

521

Q96MN2
LQRLAQIHIQQQDQC

DCTN3

126

O75935
QATLHQKDLDCQQLQ

EEA1

336

Q15075
CTQLQAHLLVIQNLD

KLRF2

106

D3W0D1
HILQQNCIALRDSIQ

CCDC150

256

Q8NCX0
NHIVFENNQQLLCLE

GALNT5

896

Q7Z7M9
VQQLHQNLHRLQILC

CCDC30

241

Q5VVM6
QNLHRLQILCNSAEN

CCDC30

246

Q5VVM6
DINICNQNGLNALHL

ANK3

66

Q12955
LHSIQIANHICNLIQ

LYST

706

Q99698
IANHICNLIQKGNIV

LYST

711

Q99698
LLQEICNLLIQQASN

DNAH9

361

Q9NYC9
NICTQVIDQNQNLHG

FBXO30

291

Q8TB52
LCSQAKLQAQQELLQ

FES

371

P07332
ELQAQVENNQCISLL

GOLGA8A

341

A7E2F4
ILGLQVQQAEHCSIQ

REXO4

371

Q9GZR2
LQCEANVRELHQLQN

SLK

1136

Q9H2G2
QRQVHECLTQLELIN

SYNE1

8046

Q8NF91
VQIILESCHNQNILG

SND1

261

Q7KZF4
IQNTQCLLNVEHLSA

SND1

821

Q7KZF4
AQIQKVNICLQNLIH

SAPCD1

101

Q5SSQ6
IEELNAAINLCQQQL

MLXIPL

721

Q9NP71
ECLNLLQQSVHQAGQ

OSBPL10

291

Q9BXB5
VILLNCAQHLSQRLQ

SLC36A3

91

Q495N2
LQFCHQRLQIISQAL

CLHC1

231

Q8NHS4
QLCIIVQTHSLQALQ

XKR4

321

Q5GH76
QHLVAALLAQLCQPQ

RPAP1

1176

Q9BWH6
LCEQHCAILLQTEQN

TTC21A

941

Q8NDW8
LGNQLQLNQHCLDTA

BRF1

96

Q92994
IVQLCFNEQSQQLLA

ZNFX1

481

Q9P2E3
QELAQVQHSIGQLCN

TRIP11

1286

Q15643
HQQQKLALQDFLELC

nan

31

Q9H521
VQQLCDINLLNQIHA

HIVEP1

1506

P15822
LQHDAQEVLQCILGN

USP1

196

O94782