Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpropionate-CoA ligase activity

ACSM3 ACSS2

1.22e-054292GO:0050218
GeneOntologyMolecularFunctionshort-chain fatty acid-CoA ligase activity

ACSM3 ACSS2

1.22e-054292GO:0031955
GeneOntologyMolecularFunctionpotassium ion leak channel activity

KCNK6 KCNK1

2.41e-0416292GO:0022841
GeneOntologyMolecularFunctionnarrow pore channel activity

KCNK6 KCNK1

3.43e-0419292GO:0022842
GeneOntologyMolecularFunctionleak channel activity

KCNK6 KCNK1

3.43e-0419292GO:0022840
GeneOntologyMolecularFunctionfatty acid ligase activity

ACSM3 ACSS2

6.48e-0426292GO:0015645
GeneOntologyMolecularFunctionCoA-ligase activity

ACSM3 ACSS2

6.99e-0427292GO:0016405
GeneOntologyMolecularFunctionoutward rectifier potassium channel activity

KCNK6 KCNK1

6.99e-0427292GO:0015271
GeneOntologyMolecularFunctioninward rectifier potassium channel activity

KCNK6 KCNK1

7.52e-0428292GO:0005242
GeneOntologyMolecularFunctionacid-thiol ligase activity

ACSM3 ACSS2

9.23e-0431292GO:0016878
GeneOntologyMolecularFunctionligase activity, forming carbon-sulfur bonds

ACSM3 ACSS2

1.61e-0341292GO:0016877
GeneOntologyMolecularFunctionATP-dependent activity

PEX1 ATP11C ACSM3 ACSS2 MCM9

1.74e-03614295GO:0140657
GeneOntologyMolecularFunctionsodium channel activity

SCN8A KCNK1

2.58e-0352292GO:0005272
GeneOntologyMolecularFunctioncalcium-dependent phospholipid binding

PLA2G4D DYSF

3.42e-0360292GO:0005544
Domain2pore_dom_K_chnl_TWIK

KCNK6 KCNK1

6.50e-063282IPR005408
DomainAB_hydrolase_lipase

LIPF LIPJ

3.24e-056282IPR006693
DomainAbhydro_lipase

LIPF LIPJ

3.24e-056282PF04083
DomainLipase_euk

LIPF LIPJ

3.24e-056282IPR025483
Domain2pore_dom_K_chnl_TASK

KCNK6 KCNK1

7.75e-059282IPR003092
Domain2pore_dom_K_chnl

KCNK6 KCNK1

2.25e-0415282IPR003280
DomainAMP-bd_C

ACSM3 ACSS2

2.91e-0417282IPR025110
DomainAMP-binding_C

ACSM3 ACSS2

2.91e-0417282PF13193
DomainK_chnl_dom

KCNK6 KCNK1

4.47e-0421282IPR013099
DomainIon_trans_2

KCNK6 KCNK1

4.47e-0421282PF07885
DomainAMP-binding_CS

ACSM3 ACSS2

6.89e-0426282IPR020845
DomainLIPASE_SER

LIPF LIPJ

6.89e-0426282PS00120
DomainAMP_BINDING

ACSM3 ACSS2

8.00e-0428282PS00455
DomainAMP-binding

ACSM3 ACSS2

9.19e-0430282PF00501
DomainAMP-dep_Synth/Lig

ACSM3 ACSS2

9.19e-0430282IPR000873
DomainAbhydrolase_1

LIPF LIPJ

9.81e-0431282PF00561
DomainAB_hydrolase_1

LIPF LIPJ

1.11e-0333282IPR000073
PathwayREACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS

KCNK6 KCNK1

1.51e-0411242MM14547
PathwayREACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS

KCNK6 KCNK1

1.81e-0412242M1071
PathwayREACTOME_MUSCLE_CONTRACTION

KCNK6 DYSF SCN8A KCNK1

3.54e-04203244M5485
PathwayREACTOME_PHASE_4_RESTING_MEMBRANE_POTENTIAL

KCNK6 KCNK1

4.67e-0419242M27452
PathwayREACTOME_PHASE_4_RESTING_MEMBRANE_POTENTIAL

KCNK6 KCNK1

4.67e-0419242MM15194
PathwayREACTOME_DIGESTION

LIPF CHIA

5.72e-0421242MM15526
PathwayREACTOME_DIGESTION

LIPF CHIA

6.88e-0423242M27790
PathwayREACTOME_DIGESTION_AND_ABSORPTION

LIPF CHIA

8.14e-0425242MM15557
PathwayREACTOME_DIGESTION_AND_ABSORPTION

LIPF CHIA

1.02e-0328242M27837
PathwayREACTOME_CARDIAC_CONDUCTION

KCNK6 SCN8A KCNK1

1.35e-03130243M27454
PathwayWP_FATTY_ACID_BETAOXIDATION

LIPF ACSS2

1.51e-0334242M39596
PathwayWP_FATTY_ACID_BETAOXIDATION

LIPF ACSS2

1.51e-0334242MM15937
Pubmed

A role for two-pore K⁺ channels in modulating Na⁺ absorption and Cl⁻ secretion in normal human bronchial epithelial cells.

KCNK6 KCNK1

4.02e-06429221964404
Pubmed

Potassium leak channels and the KCNK family of two-P-domain subunits.

KCNK6 KCNK1

4.41e-051229211256078
Pubmed

International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels.

KCNK6 KCNK1

6.07e-051429216382106
Pubmed

Human gingiva transcriptome during wound healing.

TSPEAR MEDAG DYSF

9.76e-0510729328005267
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

KCNK6 SCN8A KCNK1

2.12e-0413929316985003
Pubmed

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.

CYLD ATP11C ATF6 CHIA RAB3GAP2

2.36e-0468629529987050
Pubmed

Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms.

SCN8A KCNK1

6.50e-044529225979088
Cytoband10q23.31

LIPF LIPJ

2.13e-043429210q23.31
GeneFamilyPotassium two pore domain channel subfamily K

KCNK6 KCNK1

1.34e-0415212277
GeneFamilyLipases|Arylacetamide deacetylase family

LIPF LIPJ

2.93e-0422212464
GeneFamilyAcyl-CoA synthetase family

ACSM3 ACSS2

4.11e-042621240
CoexpressionGSE11864_CSF1_IFNG_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP

CD302 PRPF6 CHIA ACSM3

6.34e-05197294M3144
CoexpressionGSE14308_NAIVE_CD4_TCELL_VS_NATURAL_TREG_DN

MEDAG KCNK6 RAB3GAP2 MCM9

6.73e-05200294M3394
CoexpressionGSE39820_CTRL_VS_IL1B_IL6_IL23A_CD4_TCELL_UP

ATP11C KCNK6 MCM9 IPO11

6.73e-05200294M5602
CoexpressionAtlasDevelopingKidney_e15.5_Endothelial cells_emap-29977_k-means-cluster#3_top-relative-expression-ranked_100

THSD1 DYSF IPO11

3.34e-0546293DevelopingKidney_e15.5_Endothelial cells_emap-29977_k3_100
CoexpressionAtlasDevelopingKidney_e15.5_Endothelial cells_emap-29977_k-means-cluster#5_top-relative-expression-ranked_500

KCNK6 THSD1 DYSF IPO11

1.32e-04193294DevelopingKidney_e15.5_Endothelial cells_emap-29977_k5_500
CoexpressionAtlasDevelopingKidney_e15.5_Endothelial cells_emap-29977_k-means-cluster#3_top-relative-expression-ranked_200

THSD1 DYSF IPO11

1.69e-0479293DevelopingKidney_e15.5_Endothelial cells_emap-29977_k3_200
CoexpressionAtlasDevelopingKidney_e15.5_Endothelial cells_emap-29977_top-relative-expression-ranked_100

THSD1 DYSF IPO11

2.03e-0484293DevelopingKidney_e15.5_Endothelial cells_emap-29977_100
CoexpressionAtlasDevelopingKidney_e15.5_Endothelial cells_emap-29965_k-means-cluster#4_top-relative-expression-ranked_500

KCNK6 THSD1 DYSF IPO11

2.06e-04217294gudmap_developingKidney_e15.5_Endothelial cells_500_k4
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UROC1 ACSM3 ACSS2 KCNK1

3.59e-061622946972d45f4bd4b6522bf93295f7e9dca7c6cba1f3
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UROC1 ACSM3 ACSS2 KCNK1

3.59e-06162294de0fde4310a56dc96bfc134c44d104993526d9bc
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UROC1 ACSM3 ACSS2 KCNK1

4.14e-0616829435ce3b2b9c9997d4c101da5949c7271d6a6b8f12
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ECRG4 PDE6D DYSF SCN8A

4.87e-061752948b498eea1ec1c1f27b171025c3d08adf3687bafc
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte-Chondrocyte_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ECRG4 PDE6D DYSF SCN8A

4.87e-06175294a5db428b078938627e61b7e944c1e0c1d61ac2da
ToppCellfacs-Brain_Myeloid-Cortex-24m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHIA ACSM3 SCN8A KCNK1

5.32e-06179294bc93883c2094f2e5bfed79facd4994a23968d875
ToppCellfacs-Brain_Myeloid-Cortex-24m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHIA ACSM3 SCN8A KCNK1

5.32e-061792940cef6d2eab2015cac0dd340532b24bfec9707330
ToppCellPCW_10-12-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TSPEAR MEDAG THSD1 DYSF

5.32e-0617929435fe9961e228ce255e3317fc244efa35b5adbf8b
ToppCellPCW_10-12-Endothelial-Endothelial_mature-lymphatic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TSPEAR MEDAG THSD1 DYSF

5.32e-06179294ab3d08b51cd7a37582305615ee221c7a2af83b40
ToppCellfacs-Brain_Myeloid-Cortex-24m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHIA ACSM3 SCN8A KCNK1

5.32e-06179294bb2410b3934fcc53396b96b48e0d9843df159b89
ToppCellfacs-Brain_Myeloid-Cortex-24m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHIA ACSM3 SCN8A KCNK1

5.32e-06179294065241799cea30da62cb3b6f2f1970bd1b0f4e2b
ToppCell3'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPEAR MEDAG PLA2G4D IPO11

5.81e-06183294a90ffd9c50caa65f537a2e441e37655e1b622327
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPEAR MEDAG THSD1 DYSF

5.81e-06183294764ea07621f77fbd13a877aed5806ae2b3dfb43e
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPEAR MEDAG THSD1 DYSF

5.81e-0618329438a54216458ad57f356bb4ddf272e1af8036ddeb
ToppCell3'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPEAR MEDAG PLA2G4D IPO11

5.81e-0618329413ad20ec140ef5b96fdace3369b5befc0f40bb76
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MEDAG THSD1 DYSF IPO11

6.60e-061892941d660bceee449aebf12fc9af4c74af246837b27a
ToppCell3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LIPF THSD1 DYSF IPO11

6.60e-06189294b5fa3a619e3b554a1a45a551c9b6369075fe5615
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MEDAG THSD1 DYSF IPO11

6.74e-06190294b2bd2cb384bb8a5662064ed1aee68e905e1f780d
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MEDAG THSD1 DYSF IPO11

6.74e-0619029432400c62cb9de4c2b24af4206c21a0215ab12212
ToppCellwk_15-18-Endothelial-Lymph_endothelial-Intermediate_lymphatic_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

MEDAG THSD1 DYSF IPO11

6.88e-06191294d25ac3206fe205a100cfee26431ff32c14c1938f
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPEAR MEDAG THSD1 IPO11

7.02e-061922945388f3115ab285f3f3001af1d71543ed64b9e044
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPEAR MEDAG THSD1 IPO11

7.17e-06193294ef007b736da56529ec628fc3df86a335e7ec3f18
ToppCellTCGA-Head_and_Esophagus-Solid_Tissue_Normal-Esophagus_normal_tissue-Esophagus_normal_tissue|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

LIPF CHIA LIPJ

6.75e-051222934f091144530ac1e85f7a8296847ec08753156d71
ToppCellTCGA-Head_and_Esophagus-Solid_Tissue_Normal-Esophagus_normal_tissue|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

LIPF CHIA LIPJ

6.75e-051222939f48ba786d913182021b3e42349fb84934b855b8
ToppCellTCGA-Head_and_Esophagus-Solid_Tissue_Normal-Esophagus_normal_tissue-Esophagus_normal_tissue-2|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

LIPF CHIA LIPJ

8.15e-051302933450b9edc7360f8494b5e2ded3132c508bbc971b
ToppCellLPS-antiTNF-Endothelial-Mes-Like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ECRG4 KCNK6 MAK

1.45e-0415829350df52d64d07178975563abd98ce4fddb9f2f7ef
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ECRG4 MAK ACSM3

1.56e-0416229322f1abd20f43bc7e7fc46969da9962faf70ae5d2
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ECRG4 MAK ACSM3

1.56e-04162293966df4558140c3d541999ab553f201ae76a1c401
ToppCellE12.5-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

THSD1 DYSF IPO11

1.59e-04163293c21114826bee1b05b411984326fef6b6e0d05316
ToppCellE12.5-Endothelial-lymphatic_endothelial_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

THSD1 DYSF IPO11

1.59e-041632935d49414432db259a19df50d7944581d00b69f537
ToppCellfacs-Aorta-Heart-24m-Endothelial-coronary_vascular_endothelial_cell|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP11C ACSM3 ACSS2

1.62e-041642935ee3729fab794d7acb172d14ec5d91aa1a61cd61
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UROC1 ACSM3 KCNK1

1.74e-04168293b14fd50232887b6dca1f39014d43c6f66e5c3b5c
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)-|368C / Donor, Lineage, Cell class and subclass (all cells)

THSD1 DYSF IPO11

1.74e-04168293dae37b316ce80dfe4236c4ed7f0d4e7c340fa7b6
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)|368C / Donor, Lineage, Cell class and subclass (all cells)

THSD1 DYSF IPO11

1.74e-04168293a74c8a9e3299183fba31ce3053ef325b5dbcd104
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ECRG4 MEDAG KCNK1

1.77e-041692936937c46b119d4ce382fc8c2fa5925ede5ae89c81
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-mesothelial_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ECRG4 MEDAG KCNK1

1.77e-041692930cece9b2bb1f58e465c20ec8735a4fc3c1021f03
ToppCellLymphoid-Lymphoid-B_cells_(cycle)|Lymphoid / shred on cell class and cell subclass (v4)

ATP11C MCM9 SCN8A

1.86e-04172293f39822afcc35f0fbf68b8ffd1894e4b6c8d7a80c
ToppCellmetastatic_Lymph_Node-Endothelial_cells-Lymphatic_ECs|metastatic_Lymph_Node / Location, Cell class and cell subclass

MEDAG THSD1 IPO11

1.93e-04174293d551bc29afef071adf4c9bb80345352ec33441d8
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPEAR SCML2 DYSF

1.96e-0417529343be63976da5ad0764d24d90919a77ce46068f52
ToppCellEndothelial-B-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

TSPEAR MEDAG IPO11

2.00e-04176293b288116a4588a1f9db9d49af92cea118937c9201
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LIPF CD302 MAK

2.00e-04176293b0b87eebcf5c994386b39ca607e17f10e9d9de74
ToppCellmetastatic_Lymph_Node-Endothelial_cells|metastatic_Lymph_Node / Location, Cell class and cell subclass

MEDAG THSD1 IPO11

2.03e-0417729371bf5d4bc67bda37a0499e5ec01af7dd5254041d
ToppCell3'-GW_trimst-1-LargeIntestine-Endothelial-lymphatic_endothelial|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPEAR MEDAG DYSF

2.06e-041782934ef6344d0ffc9c55b1240bee94b741382f1427bb
ToppCell3'-GW_trimst-1-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPEAR MEDAG DYSF

2.06e-04178293c65932cbedbbfacb6f0299280663fe7c88dba72b
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-lymphatic_endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPEAR DYSF IPO11

2.10e-04179293abc6797bd3884aa75dca58fcb2523ee321243ab1
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPEAR DYSF IPO11

2.10e-041792930b996d6e881f31e6b80d359f7caac70ecdeb9982
ToppCell3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDE6D THSD1 DYSF

2.10e-04179293ec1d7017da325647b629de703135a404bbdc627d
ToppCell15-Distal-Epithelial-Neuroendocrine|Distal / Age, Tissue, Lineage and Cell class

LIPF TSPEAR PLA2G4D

2.10e-04179293bc04789f0fbd293fdcea66acba8cf227af251b7a
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ECRG4 CD302 LIPJ

2.20e-04182293af65f0fc3f9e5d9ce69ee5faaf5b6cb7f8412e0c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ECRG4 CD302 LIPJ

2.20e-04182293b7d532feb73167e05475855061b35a209583f44c
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MEDAG DYSF IPO11

2.20e-04182293fc020d784ab81af80d9331cc322b7c259284eaef
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ECRG4 MEDAG CD302

2.24e-041832937e5c467fd1b156b928f1611a12ab4affb9f714b7
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ECRG4 MEDAG CD302

2.24e-0418329363294d66e3ccf152ffe5d1237106764c14390b62
ToppCellP07-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ECRG4 MEDAG CD302

2.27e-0418429301257e5c12e38b849fd3d9496c43ded666249ba5
ToppCell(6)_Endothelial-F_(Lymphatics)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

THSD1 DYSF IPO11

2.27e-0418429303ea613e00b45c81b752c14505a0538d698f551e
ToppCell5'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCNK6 THSD1 DYSF

2.27e-0418429397e97de52daaff8840f4ee76a94ba5e3f79de7ce
ToppCelldroplet-Lung-21m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LIPF CD302 MAK

2.27e-0418429315ea746c77785120f69f9ab370fb7eb9b70692f8
ToppCelldroplet-Lung-21m-Hematologic-myeloid-alveolar_macrophage|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LIPF CD302 MAK

2.27e-04184293bd5e8fc453a6393b8778734a2c3c2f1281769bcd
ToppCell3'-Child09-12-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPEAR MEDAG IPO11

2.31e-041852939de1db2ce9e44956b1214daf6e1e161334679c88
ToppCellPCW_13-14-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TSPEAR MEDAG DYSF

2.31e-041852933be9e05b929ac4d956b1d53284072f668a6c1959
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THSD1 DYSF IPO11

2.31e-04185293241ea1e178fffef9e7df971de739e794332d5173
ToppCell3'-Child09-12-SmallIntestine-Endothelial-lymphatic_endothelial|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPEAR MEDAG IPO11

2.31e-0418529318f5d9438c76e37988a7d17aa2a080af6bedbfc4
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TSPEAR THSD1 DYSF

2.31e-04185293f9f48251bc33eb6bf2cff580d1a3207d21450aa0
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIPF CD302 MAK

2.31e-04185293afbb88325e4a81c15ac1d0a004e3e1f4ba2ee87b
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPEAR MEDAG DYSF

2.31e-04185293fb84fcf7f51f53489bcb3962fa9cb483e48257ed
ToppCellPCW_13-14-Endothelial-Endothelial_mature-lymphatic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TSPEAR MEDAG DYSF

2.31e-04185293c3dd64a726cb8a1fe048683c266b7532a714a52e
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THSD1 DYSF IPO11

2.35e-04186293e9d12f2fcd346fc8d00f7178324ea5997628df8a
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPEAR MEDAG DYSF

2.35e-041862939d250d5ae7cf9129be05b41d70cb6c3a046c5f1e
ToppCell356C-Endothelial_cells-Endothelial-E-|356C / Donor, Lineage, Cell class and subclass (all cells)

SCML2 THSD1 DYSF

2.35e-041862932e024097ee361eeb1d855a4edb8ac8cdad35da06
ToppCell356C-Endothelial_cells-Endothelial-E|356C / Donor, Lineage, Cell class and subclass (all cells)

SCML2 THSD1 DYSF

2.35e-04186293c3449e54454009973818fc1101933c6f0168258c
ToppCellfacs-Heart-LA-24m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEDAG CD302 CHIA

2.35e-04186293ed0a91f47e77fe21d4c7678d0f2a7c5f97d63dda
ToppCellPCW_07-8.5-Endothelial-Endothelial_mature-lymphatic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TSPEAR THSD1 DYSF

2.35e-041862935d94e6dd2c92e0c46badeb1e6eb54b69af855a66
ToppCellPCW_07-8.5-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TSPEAR THSD1 DYSF

2.35e-041862931da52e13096dfe4eb08bd0e7461cb3809b3b3deb
ToppCellControl-Endothelial-Endothelial-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP11C THSD1 DYSF

2.38e-04187293ea9d34bcd3bd1f36745846309ede349773de501a
ToppCellfacs-Heart-LA-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEDAG CD302 CHIA

2.38e-041872931669df899b1759c338ffce196fe009840123cfcd
ToppCellfacs-Heart-LA-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEDAG CD302 CHIA

2.38e-04187293f3ef3f5a761f8306edc39bf16e76e44aae6fa7f6
ToppCellE12.5-Endothelial|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

THSD1 DYSF IPO11

2.38e-04187293b8ed57b3c39ffbf750cd08a3e03ec11dae43d00e
ToppCell368C-Lymphocytic-NK_cells-NK_cell_D3|368C / Donor, Lineage, Cell class and subclass (all cells)

CYLD PEX1 MCM9

2.42e-04188293ecc2364d946f97ae0212fd6739960c9fc75e4919
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPEAR THSD1 DYSF

2.42e-04188293524a12f433c7b6f33fad36c0716afa06cd3235e9
ToppCellEndothelial-endothelial_cell_of_lymph_vessel|World / Lineage, Cell type, age group and donor

TSPEAR THSD1 DYSF

2.42e-0418829380910dcbb51990f2baed240f319456c0d3fa2065
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPEAR THSD1 DYSF

2.42e-04188293d2610b81b3c7f22977b5e2137b1f61410fc4ef16
ToppCellControl-Endothelial-Endothelial-Alv_Gen_Intermediate|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP11C THSD1 DYSF

2.46e-041892935d7ae1ead7f4fbaeec26f651833c9c2106e1e4d1
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TSPEAR THSD1 DYSF

2.46e-0418929355a1776a4ce049959b3f13a43744c7314bc1f00a
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

UROC1 THSD1 DYSF

2.46e-041892939e58411e51019ca59e78d3e737d65d2bcbbea2be
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THSD1 DYSF IPO11

2.46e-04189293a34f008dfcee4012977bbc5b60de6f0329ca2f65
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THSD1 DYSF IPO11

2.46e-0418929328b9e96a5206b7fdae9b17daf05c8f5d24b6c5ec
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-cycling_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THSD1 DYSF IPO11

2.50e-04190293d4aefae2d3164db6a9e953c54af0151501e9d1da
ToppCellwk_20-22-Endothelial-Lymph_endothelial-Intermediate_lymphatic_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

MEDAG DYSF IPO11

2.50e-04190293103e78c2233c3ee0c215a9dafe70705477e9ee5e
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ECRG4 MEDAG CD302

2.54e-041912931b26056df078674f37a6c06f6256b30cfcec21a7
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPEAR DYSF IPO11

2.58e-041922934e63d95f75fe6eb3f817e84528883e95093c5bbd
ToppCell3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THSD1 DYSF IPO11

2.58e-041922931f35efb0765e05f7f9c881849953bef3965be25a
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPEAR DYSF IPO11

2.58e-04192293fa0ef05a32c661bdd59b5a9b6f75fd647ee937f3
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THSD1 DYSF IPO11

2.58e-041922935a0615fdc217554ccd611504b16e5d97628e207d
ToppCell3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THSD1 DYSF IPO11

2.62e-04193293807fa1443b3c883cb318c71f4fca3c41d58f4910
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TSPEAR DYSF IPO11

2.62e-04193293040f6bb42aa41d0921371fdda1cc0912c4fe1930
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TSPEAR DYSF IPO11

2.62e-04193293e468287c8b30c56d1de65e8347ade233ba6cf584
ToppCellfacs-Heart-LA-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ECRG4 MEDAG CD302

2.62e-04193293124364adb3ded77282d449dd2cb039e6f2403a39
ToppCell3'-Child04-06-SmallIntestine-Epithelial-goblet-Goblet_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCNK6 ACSS2 KCNK1

2.66e-0419429349cc5f5de4380302100e8cd937f08abe317ac75e
ToppCell3'-Child04-06-SmallIntestine-Epithelial-goblet|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCNK6 ACSS2 KCNK1

2.66e-04194293fb935df966c451e659b8bde281f8aebcb632f6cf
ToppCellwk_15-18-Endothelial-Lymph_endothelial-Lymphatic_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TSPEAR DYSF IPO11

2.66e-04194293bc03d0f8dca9f4ba10db2f2274293f8b119e8951
Drug9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2; Down 200; 10uM; MCF7; HT_HG-U133A

PEX1 ATF6 MAK THSD1 KCNK1

3.95e-061982857500_DN
DrugQuinidine

KCNK6 KCNK1

8.74e-064282DB00908
Drugagrocinopine

ACSS2 KCNK1

2.18e-056282CID000127539
DrugRG-4

PDE6D STT3A

5.22e-059282CID000050370
DrugIbutilide

KCNK6 KCNK1

6.52e-0510282DB00308
DrugEstrone [53-16-7]; Down 200; 14.8uM; PC3; HT_HG-U133A

CYLD SCML2 THSD1 SCN8A

8.91e-051942846647_DN
DrugThioguanosine [85-31-4]; Down 200; 12.6uM; HL60; HT_HG-U133A

CYLD PEX1 PRPF6 RAB3GAP2

8.91e-051942841264_DN
Drug2-methyl-1-butanol

ACSM3 STT3A

9.55e-0512282CID000008723
DrugTalampicillin hydrochloride [39878-70-1]; Up 200; 7.8uM; MCF7; HT_HG-U133A

CYLD MAK DYSF RAB3GAP2

9.65e-051982843515_UP
DrugPrenylamine lactate [69-43-2]; Down 200; 9.6uM; HL60; HG-U133A

PDE6D THSD1 DYSF MCM9

9.84e-051992841737_DN
DrugNiacin [59-67-6]; Down 200; 32.4uM; PC3; HT_HG-U133A

ACSM3 THSD1 RAB3GAP2 SCN8A

9.84e-051992846702_DN
DiseaseTremor, Rubral

UROC1 SCN8A

1.11e-0416292C0750940
DiseaseAtaxia, Appendicular

UROC1 SCN8A

1.11e-0416292C0750937
DiseaseAtaxia, Truncal

UROC1 SCN8A

1.11e-0416292C0427190
DiseaseAtaxia, Motor

UROC1 SCN8A

1.11e-0416292C0278161
DiseaseAbnormal coordination

UROC1 SCN8A

1.11e-0416292C0520966
DiseaseAtaxia, Sensory

UROC1 SCN8A

1.11e-0416292C0240991
DiseaseRetinitis Pigmentosa

ATF6 PRPF6 MAK

1.45e-04104293C0035334
DiseaseAtaxia

UROC1 SCN8A

2.76e-0425292C0004134
Diseasereading and spelling ability

LIPF TSPEAR UROC1

5.74e-04166293EFO_0005301

Protein segments in the cluster

PeptideGeneStartEntry
HFLDEWLYKFSADEF

ZBTB8OS

91

Q8IWT0
GFDEAKFEDDITYWL

ECRG4

91

Q9H1Z8
LGMFYDTDDASFKWF

CD302

91

Q8IX05
FLRQYEFDGLDFDWE

CHIA

126

Q9BZP6
DWDSALFAELGYFTD

ATF6

26

P18850
FKYVFDFHAEDVFWC

ACSS2

341

Q9NR19
EEAWSFLDAFYFCFI

KCNK6

196

Q9Y257
EEEYVALGSFFFWKC

RAB3GAP2

731

Q9H2M9
FWAFSFDEMAKYDLP

LIPJ

106

Q5W064
AYELFDSVDFDQWFK

IPO11

461

Q9UI26
LEDDWNFLESFYFCF

KCNK1

206

O00180
EFWAFSFDEMAKYDL

LIPF

136

P07098
YFKGQCLEEWFFEFG

PDE6D

81

O43924
FKADALFDFFYWFGL

MEDAG

196

Q5VYS4
FKSGDSWEELEDYDF

MAK

401

P20794
VKYGKDDSAWLFFDS

CYLD

876

Q9NQC7
WDNDKFSFDDFLGSL

DYSF

1911

O75923
SEDDWKNFAELYESF

PEX1

1246

O43933
DFKEWVEFSPYEVGF

PLA2G4D

476

Q86XP0
KEFEDFWEYYKSDPF

MCM9

286

Q9NXL9
DSDLGDAWAFFYKFE

PRPF6

871

O94906
AEEGFYKFHNWFDDR

STT3A

61

P46977
DKDGYFWFVARADDV

ACSM3

466

Q53FZ2
FLGSFFISWDKDFYD

ATP11C

371

Q8NB49
FDGWSGAFDYWCKYD

SCML2

206

Q9UQR0
EKFFFWDYGNAFLLE

UROC1

396

Q96N76
LKFECFYFKEAGDYW

THSD1

86

Q9NS62
SEDDFETFYEIWEKF

SCN8A

1781

Q9UQD0
ALDWEFFSVGEDYFL

TSPEAR

586

Q8WU66