Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	peptidyltransferase activity	GGTLC2 GGT1 GGT3P	2.64e-06	6	103	3	GO:0000048
GeneOntologyMolecularFunction	leukotriene-C(4) hydrolase	GGTLC2 GGT1 GGT3P	2.64e-06	6	103	3	GO:0002951
GeneOntologyMolecularFunction	leukotriene C4 gamma-glutamyl transferase activity	GGTLC2 GGT1 GGT3P	7.33e-06	8	103	3	GO:0103068
GeneOntologyMolecularFunction	glutathione hydrolase activity	GGTLC2 GGT1 GGT3P	1.09e-05	9	103	3	GO:0036374
GeneOntologyMolecularFunction	omega peptidase activity	GGTLC2 GGT1 GGT3P	7.11e-05	16	103	3	GO:0008242
GeneOntologyMolecularFunction	threonine-type peptidase activity	GGTLC2 GGT1 GGT3P	1.43e-04	20	103	3	GO:0070003
GeneOntologyMolecularFunction	aminoacyltransferase activity	UBE2L6 NEDD4L HECTD3 RC3H1 GGTLC2 DCST1 HDAC7 GGT1 GGT3P TGM7	4.25e-04	532	103	10	GO:0016755
GeneOntologyMolecularFunction	catalytic activity, acting on a nucleic acid	SGIP1 POLR1A DIS3L NOB1 DDX56 CHD1 GGTLC2 GGT1 GGT3P DNA2 TRMT12	4.95e-04	645	103	11	GO:0140640
GeneOntologyMolecularFunction	structural constituent of presynaptic active zone	ERC2 RIMS1	7.23e-04	8	103	2	GO:0098882
GeneOntologyBiologicalProcess	cysteine biosynthetic process	GGTLC2 GGT1 GGT3P	7.25e-06	8	106	3	GO:0019344
GeneOntologyBiologicalProcess	peptide modification	GGTLC2 GGT1 GGT3P	1.54e-05	10	106	3	GO:0031179
GeneOntologyBiologicalProcess	leukotriene D4 biosynthetic process	GGTLC2 GGT1 GGT3P	1.54e-05	10	106	3	GO:1901750
GeneOntologyBiologicalProcess	glutathione catabolic process	GGTLC2 GGT1 GGT3P	2.11e-05	11	106	3	GO:0006751
GeneOntologyBiologicalProcess	regulation of postsynaptic membrane neurotransmitter receptor levels	TNIK NEDD4L GIT1 ZDHHC5 DAG1 VAC14 SCRIB	2.23e-05	164	106	7	GO:0099072
GeneOntologyBiologicalProcess	leukotriene D4 metabolic process	GGTLC2 GGT1 GGT3P	2.81e-05	12	106	3	GO:1901748
GeneOntologyBiologicalProcess	leukotriene metabolic process	GGTLC2 GGT1 GGT3P ABCC10	5.76e-05	41	106	4	GO:0006691
GeneOntologyBiologicalProcess	cysteine metabolic process	GGTLC2 GGT1 GGT3P	7.04e-05	16	106	3	GO:0006534
GeneOntologyBiologicalProcess	glutathione biosynthetic process	GGTLC2 GGT1 GGT3P	1.41e-04	20	106	3	GO:0006750
GeneOntologyBiologicalProcess	sulfur amino acid biosynthetic process	GGTLC2 GGT1 GGT3P	1.64e-04	21	106	3	GO:0000097
GeneOntologyBiologicalProcess	nonribosomal peptide biosynthetic process	GGTLC2 GGT1 GGT3P	1.89e-04	22	106	3	GO:0019184
GeneOntologyBiologicalProcess	leukotriene biosynthetic process	GGTLC2 GGT1 GGT3P	1.89e-04	22	106	3	GO:0019370
MousePheno	abnormal circulating glutathione level	GGTLC2 GGT1 GGT3P	1.66e-06	5	78	3	MP:0030652
MousePheno	increased circulating glutathione level	GGTLC2 GGT1 GGT3P	1.66e-06	5	78	3	MP:0030653
MousePheno	glutathionuria	GGTLC2 GGT1 GGT3P	1.66e-06	5	78	3	MP:0013730
MousePheno	increased glutathione level	GGTLC2 GGT1 GGT3P	1.66e-06	5	78	3	MP:0012606
MousePheno	decreased circulating cysteine level	GGTLC2 GGT1 GGT3P	5.76e-06	7	78	3	MP:0030626
MousePheno	decreased cysteine level	GGTLC2 GGT1 GGT3P	9.17e-06	8	78	3	MP:0030623
MousePheno	epididymis hypoplasia	GGTLC2 GGT1 GGT3P	9.17e-06	8	78	3	MP:0004932
MousePheno	nervous	GGTLC2 GGT1 GGT3P	1.37e-05	9	78	3	MP:0008912
MousePheno	failure of copulatory plug deposition	GGTLC2 GGT1 GGT3P	1.95e-05	10	78	3	MP:0030983
MousePheno	seminal vesicle hypoplasia	GGTLC2 GGT1 GGT3P	1.95e-05	10	78	3	MP:0005148
MousePheno	ovary hypoplasia	GGTLC2 GGT1 GGT3P	1.95e-05	10	78	3	MP:0005158
MousePheno	abnormal circulating cysteine level	GGTLC2 GGT1 GGT3P	2.67e-05	11	78	3	MP:0030624
MousePheno	absent tertiary ovarian follicles	GGTLC2 GGT1 GGT3P	2.67e-05	11	78	3	MP:0011130
MousePheno	abnormal cysteine level	GGTLC2 GGT1 GGT3P	4.59e-05	13	78	3	MP:0030621
MousePheno	decreased glutathione level	GGTLC2 GGT1 GGT3P	4.59e-05	13	78	3	MP:0012604
MousePheno	abnormal glutathione level	GGTLC2 GGT1 GGT3P	4.59e-05	13	78	3	MP:0012603
MousePheno	priapism	GGTLC2 GGT1 GGT3P	5.82e-05	14	78	3	MP:0003415
MousePheno	abnormal copulatory plug deposition	GGTLC2 GGT1 GGT3P	8.88e-05	16	78	3	MP:0030982
MousePheno	decreased spleen red pulp amount	GGTLC2 GGT1 GGT3P	8.88e-05	16	78	3	MP:0008477
MousePheno	absent lens vesicle	MAB21L2 MAB21L1	9.19e-05	3	78	2	MP:0009725
MousePheno	failure of superovulation	GGTLC2 GGT1 GGT3P	1.28e-04	18	78	3	MP:0031422
MousePheno	abnormal penile erection	GGTLC2 GGT1 GGT3P	1.28e-04	18	78	3	MP:0001379
MousePheno	oocyte degeneration	GGTLC2 GGT1 GGT3P	1.28e-04	18	78	3	MP:0009093
MousePheno	increased circulating growth hormone level	GGTLC2 GGT1 GGT3P	1.52e-04	19	78	3	MP:0005123
MousePheno	abnormal copulation physiology	GGTLC2 GGT1 GGT3P	1.52e-04	19	78	3	MP:0031627
MousePheno	abnormal sexual interaction	MAOA LAMA2 GGTLC2 GGT1 GGT3P	1.77e-04	94	78	5	MP:0002566
MousePheno	small vertebrae	GGTLC2 GGT1 GGT3P	2.38e-04	22	78	3	MP:0004610
MousePheno	increased growth hormone level	GGTLC2 GGT1 GGT3P	2.73e-04	23	78	3	MP:0005137
MousePheno	uterus hypoplasia	GGTLC2 GGT1 GGT3P	2.73e-04	23	78	3	MP:0001121
MousePheno	abnormal copulation behavior	GGTLC2 GGT1 GGT3P	3.11e-04	24	78	3	MP:0009697
MousePheno	nuclear cataract	GGTLC2 GGT1 GGT3P	3.96e-04	26	78	3	MP:0010254
MousePheno	diluted coat color	GGTLC2 GGT1 GGT3P VAC14	4.42e-04	64	78	4	MP:0000371
MousePheno	aminoaciduria	GGTLC2 GGT1 GGT3P	5.50e-04	29	78	3	MP:0003311
MousePheno	pigmentation phenotype	MON2 CARMIL2 MAB21L2 GGTLC2 TNRC6C NPHP4 HDAC7 GGT1 GGT3P VAC14 MAB21L1	6.56e-04	624	78	11	MP:0001186
MousePheno	anovulation	GGTLC2 GGT1 GGT3P	8.08e-04	33	78	3	MP:0008869
MousePheno	decreased circulating follicle stimulating hormone level	GGTLC2 GGT1 GGT3P	8.83e-04	34	78	3	MP:0002790
MousePheno	hindlimb paralysis	LAMA2 GGTLC2 GGT1 GGT3P	9.82e-04	79	78	4	MP:0000755
Domain	GGT_peptidase	GGTLC2 GGT1 GGT3P	5.61e-06	7	103	3	IPR000101
Domain	G_GLU_TRANSPEPTIDASE	GGTLC2 GGT1 GGT3P	5.61e-06	7	103	3	PS00462
Domain	G_glu_transpept	GGTLC2 GGT1 GGT3P	5.61e-06	7	103	3	PF01019
Domain	K_chnl_volt-dep_ERG	KCNH6 KCNH2	9.00e-05	3	103	2	IPR003967
Domain	Leu-rich_rpt	CARMIL2 FBXL15 LRRC70 CPN2 LRRC30 CEP72 LRRC8B SCRIB	1.28e-04	271	103	8	IPR001611
Domain	DC_STAMP-like	DCSTAMP DCST1	1.79e-04	4	103	2	IPR012858
Domain	DC_STAMP	DCSTAMP DCST1	1.79e-04	4	103	2	PF07782
Domain	Mab-21-like_1/2	MAB21L2 MAB21L1	2.98e-04	5	103	2	IPR020950
Domain	-	CARMIL2 FBXL15 LRRC70 CPN2 LRRC30 CEP72 LRRC8B SCRIB	4.03e-04	321	103	8	3.80.10.10
Domain	Leu-rich_rpt_typical-subtyp	LRRC70 CPN2 LRRC30 CEP72 LRRC8B SCRIB	4.45e-04	177	103	6	IPR003591
Domain	LRR_TYP	LRRC70 CPN2 LRRC30 CEP72 LRRC8B SCRIB	4.45e-04	177	103	6	SM00369
Domain	L_dom-like	CARMIL2 FBXL15 LRRC70 CPN2 LRRC30 CEP72 LRRC8B SCRIB	4.65e-04	328	103	8	IPR032675
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MON2 HIVEP2 ATP13A1 NOB1 ZDHHC5 DDX56 TNRC6C NPHP4 PRAG1 HDAC7 FZR1 VAC14 LLGL2 KCNH2 RPTOR SEC16A PXN ABCC10	8.92e-09	1105	108	18	35748872
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	HIVEP2 CARMIL2 NEDD4L GIT1 PRAG1 HDAC7 ARAF DENND4C RPTOR SRGAP1 SEC16A KIF14 PLEKHA5 SCRIB MAP4K4	7.36e-08	861	108	15	36931259
Pubmed	Lung lining fluid glutathione attenuates IL-13-induced asthma.	GGTLC2 GGT1 GGT3P	2.90e-07	5	108	3	18063838
Pubmed	Gamma-glutamyltranspeptidase knockout mice as a model for understanding the consequences of diminished glutathione on T cell-dependent immune responses.	GGTLC2 GGT1 GGT3P	2.90e-07	5	108	3	10940879
Pubmed	Cataract development in gamma-glutamyl transpeptidase-deficient mice.	GGTLC2 GGT1 GGT3P	2.90e-07	5	108	3	11095909
Pubmed	Expression of gamma-glutamyl transpeptidase in midgestation mouse yolk sac and mouse visceral yolk sac carcinoma cells.	GGTLC2 GGT1 GGT3P	2.90e-07	5	108	3	7641802
Pubmed	Phenotypic characterization of Ggt1(dwg/dwg) mice,a mouse model for hereditary γ-glutamyltransferase deficiency.	GGTLC2 GGT1 GGT3P	2.90e-07	5	108	3	23615310
Pubmed	The mouse skin carcinogenesis model.	GGTLC2 GGT1 GGT3P	2.90e-07	5	108	3	9627710
Pubmed	Gamma-glutamyl transpeptidase and its role in melanogenesis: redox reactions and regulation of tyrosinase.	GGTLC2 GGT1 GGT3P	2.90e-07	5	108	3	12453183
Pubmed	gamma-glutamyltranspeptidase-deficient knockout mice as a model to study the relationship between glutathione status, mitochondrial function, and cellular function.	GGTLC2 GGT1 GGT3P	2.90e-07	5	108	3	11003618
Pubmed	Gamma-glutamyl transpeptidase gene organization and expression: a comparative analysis in rat, mouse, pig and human species.	GGTLC2 GGT1 GGT3P	2.90e-07	5	108	3	10392451
Pubmed	Immunocytochemical localization of gamma-glutamyltranspeptidase during fetal development of mouse kidney.	GGTLC2 GGT1 GGT3P	2.90e-07	5	108	3	2891746
Pubmed	Hyperoxia-induced lung injury in gamma-glutamyl transferase deficiency is associated with alterations in nitrosative and nitrative stress.	GGTLC2 GGT1 GGT3P	2.90e-07	5	108	3	19850887
Pubmed	Reversible skeletal abnormalities in gamma-glutamyl transpeptidase-deficient mice.	GGTLC2 GGT1 GGT3P	2.90e-07	5	108	3	12810527
Pubmed	Growth retardation and cysteine deficiency in gamma-glutamyl transpeptidase-deficient mice.	GGTLC2 GGT1 GGT3P	2.90e-07	5	108	3	8755578
Pubmed	Reproductive defects in gamma-glutamyl transpeptidase-deficient mice.	GGTLC2 GGT1 GGT3P	2.90e-07	5	108	3	11089562
Pubmed	Liver-Specific Overexpression of Gamma-Glutamyltransferase Ameliorates Insulin Sensitivity of Male C57BL/6 Mice.	GGTLC2 GGT1 GGT3P	2.90e-07	5	108	3	28660214
Pubmed	Bleomycin-induced pulmonary fibrosis is attenuated in gamma-glutamyl transpeptidase-deficient mice.	GGTLC2 GGT1 GGT3P	2.90e-07	5	108	3	12468440
Pubmed	N-acetyl-cysteine prevents age-related hearing loss and the progressive loss of inner hair cells in γ-glutamyl transferase 1 deficient mice.	GGTLC2 GGT1 GGT3P	2.90e-07	5	108	3	26977590
Pubmed	Gamma-glutamyl transferase deficiency results in lung oxidant stress in normoxia.	GGTLC2 GGT1 GGT3P	2.90e-07	5	108	3	12225953
Pubmed	Identification of a sixth promoter that directs the transcription of gamma-glutamyl transpeptidase type III RNA in mouse.	GGTLC2 GGT1 GGT3P	2.90e-07	5	108	3	7775425
Pubmed	Cloning of cDNA and genomic structure of the mouse gamma-glutamyl transpeptidase-encoding gene.	GGTLC2 GGT1 GGT3P	2.90e-07	5	108	3	8566783
Pubmed	Therapeutic Effect of GGsTop, Selective Gamma-glutamyl Transpeptidase Inhibitor, on a Mouse Model of 5-Fluorouracil-induced Oral Mucositis.	GGTLC2 GGT1 GGT3P	2.90e-07	5	108	3	30591459
Pubmed	Mice with genetic gamma-glutamyl transpeptidase deficiency exhibit glutathionuria, severe growth failure, reduced life spans, and infertility.	GGTLC2 GGT1 GGT3P	2.90e-07	5	108	3	9139708
Pubmed	Analysis of site-specific glycosylation of renal and hepatic γ-glutamyl transpeptidase from normal human tissue.	GGTLC2 GGT1 GGT3P	2.90e-07	5	108	3	20622017
Pubmed	Accelerated methylmercury elimination in gamma-glutamyl transpeptidase-deficient mice.	GGTLC2 GGT1 GGT3P	2.90e-07	5	108	3	9546365
Pubmed	In vivo reversal of glutathione deficiency and susceptibility to in vivo dexamethasone-induced apoptosis by N-acetylcysteine and L-2-oxothiazolidine-4-carboxylic acid, but not ascorbic acid, in thymocytes from gamma-glutamyltranspeptidase-deficient knockout mice.	GGTLC2 GGT1 GGT3P	2.90e-07	5	108	3	11795900
Pubmed	gamma-Glutamyl transpeptidase. What does the organization and expression of a multipromoter gene tell us about its functions?	GGTLC2 GGT1 GGT3P	2.90e-07	5	108	3	7485380
Pubmed	Accumulation of DNA damage in the organs of mice deficient in gamma-glutamyltranspeptidase.	GGTLC2 GGT1 GGT3P	2.90e-07	5	108	3	10751614
Pubmed	Type VI RNA is the major gamma-glutamyl transpeptidase RNA in the mouse small intestine.	GGTLC2 GGT1 GGT3P	2.90e-07	5	108	3	7523374
Pubmed	Cardio-reno-hepatic interactions in acute heart failure: the role of γ-glutamyl transferase.	GGTLC2 GGT1 GGT3P	2.90e-07	5	108	3	24698228
Pubmed	Inhibiting lung lining fluid glutathione metabolism with GGsTop as a novel treatment for asthma.	GGTLC2 GGT1 GGT3P	2.90e-07	5	108	3	25132819
Pubmed	Characterization of the dwg mutations: dwg and dwg(Bayer) are new mutant alleles of the Ggt1 gene.	GGTLC2 GGT1 GGT3P	2.90e-07	5	108	3	19760322
Pubmed	gamma-Glutamyl transferase (GGT) deficiency in the GGTenu1 mouse results from a single point mutation that leads to a stop codon in the first coding exon of GGT mRNA.	GGTLC2 GGT1 GGT3P	2.90e-07	5	108	3	10474818
Pubmed	The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.	TNIK TNRC6C PRAG1 TRAP1 PLPPR4 SRGAP1 ERC2 MAP4K4	4.31e-07	218	108	8	33378226
Pubmed	Gamma-glutamyltranspeptidase stimulates receptor activator of nuclear factor-kappaB ligand expression independent of its enzymatic activity and serves as a pathological bone-resorbing factor.	GGTLC2 GGT1 GGT3P	5.78e-07	6	108	3	14634009
Pubmed	Overexpression of gamma-glutamyltransferase in transgenic mice accelerates bone resorption and causes osteoporosis.	GGTLC2 GGT1 GGT3P	5.78e-07	6	108	3	17363454
Pubmed	Six mRNAs with different 5' ends are encoded by a single gamma-glutamyltransferase gene in mouse.	GGTLC2 GGT1 GGT3P	5.78e-07	6	108	3	8101000
Pubmed	Four distinct membrane-bound dipeptidase RNAs are differentially expressed and show discordant regulation with gamma-glutamyl transpeptidase.	GGTLC2 GGT1 GGT3P	5.78e-07	6	108	3	8663190
Pubmed	Mapping of human gamma-glutamyl transpeptidase genes on chromosome 22 and other human autosomes.	GGTLC2 GGT1 GGT3P	5.78e-07	6	108	3	8104871
Pubmed	Disruption of gamma-glutamyl leukotrienase results in disruption of leukotriene D(4) synthesis in vivo and attenuation of the acute inflammatory response.	GGTLC2 GGT1 GGT3P	5.78e-07	6	108	3	11463821
Pubmed	Effect of atorvastatin on the expression of gamma-glutamyl transferase in aortic atherosclerotic plaques of apolipoprotein E-knockout mice.	GGTLC2 GGT1 GGT3P	5.78e-07	6	108	3	25326709
Pubmed	Gamma-glutamyl leukotrienase, a novel endothelial membrane protein, is specifically responsible for leukotriene D(4) formation in vivo.	GGTLC2 GGT1 GGT3P	5.78e-07	6	108	3	12163373
Pubmed	Ablation of Mrds1/Ofcc1 induces hyper-γ-glutamyl transpeptidasemia without abnormal head development and schizophrenia-relevant behaviors in mice.	GGTLC2 GGT1 GGT3P	5.78e-07	6	108	3	22242126
Pubmed	γ-Glutamyltranspeptidase is an endogenous activator of Toll-like receptor 4-mediated osteoclastogenesis.	GGTLC2 GGT1 GGT3P	1.01e-06	7	108	3	27775020
Pubmed	Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation.	GGTLC2 GGT1 GGT3P	1.01e-06	7	108	3	32284594
Pubmed	Defective epidermal growth factor gene expression in mice with polycystic kidney disease.	GGTLC2 GGT1 GGT3P	1.01e-06	7	108	3	1968405
Pubmed	m6A eraser FTO modulates autophagy by targeting SQSTM1/P62 in the prevention of canagliflozin against renal fibrosis.	GGTLC2 GGT1 GGT3P	1.01e-06	7	108	3	36685533
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	MON2 DNAJB11 HECTD3 P3H3 DIS3L DDX56 ARAF RSBN1 FBN2 RPTOR SEC16A LRRC8B SCRIB DNA2 VAV1	1.93e-06	1116	108	15	31753913
Pubmed	Renalase regulates renal dopamine and phosphate metabolism.	GGTLC2 GGT1 GGT3P	3.44e-06	10	108	3	23863468
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	TNIK NEDD4L DIS3L NOB1 DDX56 TNRC6C ARAF DENND4C VAC14 RPTOR SEC16A PXN PLEKHA5 MAP4K4	4.21e-06	1038	108	14	26673895
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	TNIK TNRC6C CEP72 SEC16A ERC2 PLEKHA5 SCRIB	6.92e-06	225	108	7	12168954
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	TNIK NEDD4L ZDHHC5 DAG1 LLGL2 SEC16A PLEKHA5 SCRIB MAP4K4	6.97e-06	421	108	9	36976175
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TNIK SGIP1 NEDD4L GIT1 NHSL2 PLPPR4 RPTOR SEC16A ERC2 PLEKHA5 RIMS1 SCRIB MAP4K4	9.44e-06	963	108	13	28671696
Pubmed	FOXM1 evokes 5-fluorouracil resistance in colorectal cancer depending on ABCC10.	FOXM1 ABCC10	9.55e-06	2	108	2	28051999
Pubmed	The extracellular matrix protein laminin α2 regulates the maturation and function of the blood-brain barrier.	LAMA2 DAG1	9.55e-06	2	108	2	25392494
Pubmed	The Male Abnormal Gene Family 21 (Mab21) Members Regulate Eye Development.	MAB21L2 MAB21L1	9.55e-06	2	108	2	27558071
Pubmed	FoxM1 is degraded at mitotic exit in a Cdh1-dependent manner.	FOXM1 FZR1	9.55e-06	2	108	2	18758239
Pubmed	Muscarinic receptor activation increases hERG channel expression through phosphorylation of ubiquitin ligase Nedd4-2.	NEDD4L KCNH2	9.55e-06	2	108	2	24688054
Pubmed	Both laminin and Schwann cell dystroglycan are necessary for proper clustering of sodium channels at nodes of Ranvier.	LAMA2 DAG1	9.55e-06	2	108	2	16221851
Pubmed	Dystroglycan is a dual receptor for agrin and laminin-2 in Schwann cell membrane.	LAMA2 DAG1	9.55e-06	2	108	2	8798547
Pubmed	Genomic cloning and chromosomal localization of the mouse Mab21l2 locus.	MAB21L2 MAB21L1	9.55e-06	2	108	2	10516425
Pubmed	Novel interactions between FOXM1 and CDC25A regulate the cell cycle.	FOXM1 CDC25A	9.55e-06	2	108	2	23240008
Pubmed	Depletion of Mab21l1 and Mab21l2 messages in mouse embryo arrests axial turning, and impairs notochord and neural tube differentiation.	MAB21L2 MAB21L1	9.55e-06	2	108	2	11857508
Pubmed	DC-STAMP, a novel multimembrane-spanning molecule preferentially expressed by dendritic cells.	DCSTAMP DCST1	9.55e-06	2	108	2	11169400
Pubmed	Identification of alpha-dystroglycan binding sequences in the laminin alpha2 chain LG4-5 module.	LAMA2 DAG1	9.55e-06	2	108	2	19800000
Pubmed	FOXM1 mediates GDF-15 dependent stemness and intrinsic drug resistance in breast cancer.	FOXM1 GDF15	9.55e-06	2	108	2	35066766
Pubmed	Linker molecules between laminins and dystroglycan ameliorate laminin-alpha2-deficient muscular dystrophy at all disease stages.	LAMA2 DAG1	9.55e-06	2	108	2	17389231
Pubmed	The human gamma-glutamyltransferase gene family.	GGTLC2 GGT1 GGT3P	1.03e-05	14	108	3	18357469
Pubmed	Gene dosage in the developing and adult brain in a mouse model of 22q11 deletion syndrome.	GGTLC2 GGT1 GGT3P	2.30e-05	18	108	3	17097888
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	MON2 DCAKD DIS3L ATP13A1 GDF15 ZDHHC5 TNRC6C FBN2 CEP72 PLEKHA5 DNA2	2.37e-05	754	108	11	33060197
Pubmed	Nedd4-2 modulates renal Na+-Cl- cotransporter via the aldosterone-SGK1-Nedd4-2 pathway.	NEDD4L SLC12A3	2.86e-05	3	108	2	21852580
Pubmed	Mammalian Scribble forms a tight complex with the betaPIX exchange factor.	GIT1 SCRIB	2.86e-05	3	108	2	15182672
Pubmed	Anaphase-promoting complex/cyclosome-CDH1-mediated proteolysis of the forkhead box M1 transcription factor is critical for regulated entry into S phase.	FOXM1 FZR1	2.86e-05	3	108	2	18573889
Pubmed	Developmentally regulated expression of the mouse homologues of the potassium channel encoding genes m-erg1, m-erg2 and m-erg3.	KCNH6 KCNH2	2.86e-05	3	108	2	14643686
Pubmed	Distribution of dystroglycan in normal adult mouse tissues.	LAMA2 DAG1	2.86e-05	3	108	2	9524190
Pubmed	Renal tubular NEDD4-2 deficiency causes NCC-mediated salt-dependent hypertension.	NEDD4L SLC12A3	2.86e-05	3	108	2	23348737
Pubmed	Coupling of PAK-interacting exchange factor PIX to GIT1 promotes focal complex disassembly.	GIT1 PXN	2.86e-05	3	108	2	10938112
Pubmed	Dystroglycan is not required for localization of dystrophin, syntrophin, and neuronal nitric-oxide synthase at the sarcolemma but regulates integrin alpha 7B expression and caveolin-3 distribution.	LAMA2 DAG1	2.86e-05	3	108	2	11741881
Pubmed	The anaphase-promoting complex/cyclosome co-activator, Cdh1, is a novel target of human papillomavirus 16 E7 oncoprotein in cervical oncogenesis.	FOXM1 FZR1	2.86e-05	3	108	2	35738876
Pubmed	Cell surface expression of human ether-a-go-go-related gene (hERG) channels is regulated by caveolin-3 protein via the ubiquitin ligase Nedd4-2.	NEDD4L KCNH2	2.86e-05	3	108	2	22879586
Pubmed	Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma.	GIT1 SCRIB	2.86e-05	3	108	2	19041750
Pubmed	GIT1 phosphorylation on serine 46 by PKD3 regulates paxillin trafficking and cellular protrusive activity.	GIT1 PXN	2.86e-05	3	108	2	22893698
Pubmed	Potassium Ion Channel Protein (KCNH) Levels in Patients with Fibromyalgia Syndrome.	KCNH6 KCNH2	2.86e-05	3	108	2	35818223
Pubmed	Dystrophin-associated proteins are greatly reduced in skeletal muscle from mdx mice.	LAMA2 DAG1	2.86e-05	3	108	2	1757468
Pubmed	Human lung expresses unique gamma-glutamyl transpeptidase transcripts.	GGTLC2 GGT1	2.86e-05	3	108	2	7689219
Pubmed	Identification of an intramolecular interaction important for the regulation of GIT1 functions.	GIT1 PXN	2.86e-05	3	108	2	17898078
Pubmed	Cast: a novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and munc13-1.	ERC2 RIMS1	2.86e-05	3	108	2	12163476
Pubmed	Dystroglycan is a binding protein of laminin and merosin in peripheral nerve.	LAMA2 DAG1	2.86e-05	3	108	2	7925941
Pubmed	Laminin alpha1 chain mediated reduction of laminin alpha2 chain deficient muscular dystrophy involves integrin alpha7beta1 and dystroglycan.	LAMA2 DAG1	2.86e-05	3	108	2	16504180
Pubmed	Different gamma-glutamyl transpeptidase mRNAs are expressed in human liver and kidney.	GGT1 GGT3P	2.86e-05	3	108	2	2573352
Pubmed	HERG K(+) currents in human prolactin-secreting adenoma cells.	KCNH6 KCNH2	2.86e-05	3	108	2	12634931
Pubmed	Regulation of the human ether-a-go-go-related gene (hERG) channel by Rab4 protein through neural precursor cell-expressed developmentally down-regulated protein 4-2 (Nedd4-2).	NEDD4L KCNH2	2.86e-05	3	108	2	23792956
Pubmed	USP39 facilitates breast cancer cell proliferation through stabilization of FOXM1.	FOXM1 FZR1	2.86e-05	3	108	2	36119839
Pubmed	A cell based screening approach for identifying protein degradation regulators.	FBXL15 FZR1	2.86e-05	3	108	2	28296622
Pubmed	Brain alpha-dystroglycan displays unique glycoepitopes and preferential binding to laminin-10/11.	LAMA2 DAG1	2.86e-05	3	108	2	16709410
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	MON2 TNIK NEDD4L TNRC6C RSBN1 SEC16A ERC2 SCRIB	4.17e-05	407	108	8	12693553
Pubmed	The RNF146 and tankyrase pathway maintains the junctional Crumbs complex through regulation of angiomotin.	LLGL2 PXN SCRIB	4.30e-05	22	108	3	27521426
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	MON2 TNIK DNAJB11 SGIP1 NEDD4L GIT1 ATP13A1 DAG1 TRAP1 PLPPR4 RPTOR RIMS1 MAP4K4	5.39e-05	1139	108	13	36417873
Pubmed	An alpha4 integrin-paxillin-Arf-GAP complex restricts Rac activation to the leading edge of migrating cells.	GIT1 PXN	5.71e-05	4	108	2	15793570
Interaction	YWHAH interactions	HIVEP2 CARMIL2 NEDD4L GIT1 NHSL2 PRAG1 HDAC7 ARAF DENND4C FZR1 KCNH2 RPTOR SRGAP1 SEC16A KIF14 PLEKHA5 RIMS1 SCRIB CDC25A MAP4K4	3.95e-07	1102	100	20	int:YWHAH
Interaction	YWHAG interactions	HIVEP2 CARMIL2 UBE2L6 NEDD4L GIT1 NHSL2 RC3H1 MAB21L2 PRAG1 HDAC7 ARAF DENND4C FZR1 RPTOR SRGAP1 SEC16A KIF14 PLEKHA5 SCRIB CDC25A MAP4K4	6.64e-07	1248	100	21	int:YWHAG
Interaction	ERC2 interactions	TNIK GIT1 FZR1 ERC2 RIMS1	2.00e-06	42	100	5	int:ERC2
Interaction	AP2A2 interactions	TNIK SGIP1 RC3H1 MAB21L2 WDFY4 FZR1 PXN KIF14	6.72e-06	199	100	8	int:AP2A2
Interaction	RAC1 interactions	TNIK CARMIL2 GIT1 ATP13A1 ZDHHC5 DAG1 DDX56 BRINP1 HDAC7 DENND4C LLGL2 SRGAP1 KIF14 PLEKHA5 SCRIB MAP4K4 VAV1	1.76e-05	1063	100	17	int:RAC1
Interaction	TOP3B interactions	MON2 HIVEP2 ATP13A1 NOB1 ZDHHC5 DDX56 TNRC6C NPHP4 PRAG1 HDAC7 FZR1 VAC14 LLGL2 KCNH2 RPTOR SEC16A PXN KIF14 DNA2 ABCC10	3.04e-05	1470	100	20	int:TOP3B
Interaction	LIMA1 interactions	ZDHHC5 NPHP4 WDFY4 HDAC7 DENND4C PHF1 RPTOR SEC16A KIF14 PLEKHA5	5.40e-05	429	100	10	int:LIMA1
Interaction	EPHA2 interactions	TNIK NEDD4L GIT1 ZDHHC5 DAG1 NPHP4 ARAF FZR1 LLGL2 SEC16A PLEKHA5 SCRIB MAP4K4	5.56e-05	719	100	13	int:EPHA2
Interaction	BAG2 interactions	TNIK DNAJB11 UBE2L6 RC3H1 NPHP4 ARAF XAB2 FZR1 KCNH2 RPTOR PXN KIF14	5.93e-05	622	100	12	int:BAG2
Interaction	GGTLC2 interactions	GGTLC2 GGT1	7.29e-05	3	100	2	int:GGTLC2
Interaction	TEC interactions	POLR1A FZR1 SEC16A PXN VAV1	8.56e-05	90	100	5	int:TEC
Interaction	MAGI1 interactions	DAG1 ESAM HDAC7 DENND4C RPTOR PLEKHA5	9.23e-05	147	100	6	int:MAGI1
Interaction	ARID5A interactions	MAB21L2 HDAC7 PHF1 VAC14 TGM7 CYSRT1	9.23e-05	147	100	6	int:ARID5A
Interaction	NTRK3 interactions	MON2 TNIK DNAJB11 GDF15 DENND4C RPTOR PLEKHA5 SCRIB MAP4K4	1.02e-04	374	100	9	int:NTRK3
Interaction	BORA interactions	DNAJB11 PHF1 FZR1 DNA2	1.10e-04	50	100	4	int:BORA
Cytoband	Ensembl 112 genes in cytogenetic band chr16q22	NRN1L CARMIL2 NOB1 VAC14 TLE7	7.62e-05	183	108	5	chr16q22
GeneFamily	CD molecules\|Gamma-glutamyltransferases	GGTLC2 GGT1 GGT3P	1.07e-05	13	62	3	564
GeneFamily	Membrane associated guanylate kinases\|PDZ domain containing\|Scribble complex	LLGL2 SCRIB	6.91e-05	4	62	2	1224
CoexpressionAtlas	dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_200	SGIP1 MAOA MAB21L2 ERC2 MAB21L1	6.35e-06	55	101	5	gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k1_200
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#2_top-relative-expression-ranked_1000	TNIK SGIP1 CHD1 BRINP1 IRX3 TNRC6C DACH2 ERC2 RGS17 MAB21L1	1.26e-05	377	101	10	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000_k2
CoexpressionAtlas	dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k-means-cluster#3_top-relative-expression-ranked_1000	TNIK SGIP1 MAOA MAB21L2 ERC2 LRRC8B MAB21L1	5.13e-05	202	101	7	gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k3_1000
ToppCell	368C-Myeloid-Dendritic-cDC1\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	WDFY4 VAC14 KIF14 PLEKHA5 TTC22 CDC25A	2.43e-06	161	106	6	1011094c54381d52566e24c92f89f2efc2aa3eea
ToppCell	wk_20-22-Hematologic_Lymphocytic-T_&_ILC-T_entry\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CHD1 TNRC6C HDAC7 RPTOR PPP1R1C KIF14	2.52e-06	162	106	6	a27750117e7f16a0bd07cc5f58a56becb39e800b
ToppCell	343B-Lymphocytic-CD4_T-cell-Treg_cell_4\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	NEDD4L HDAC7 FZR1 VAC14 LRRC8B TRMT12	5.08e-06	183	106	6	3cbe0175d05fd39bc430de1ef471ff2c5b56460e
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	KCNH6 DACH2 KCNH2 ERC2 RGS17 RIMS1	5.57e-06	186	106	6	b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCell	MS-CD8-antiviral_CD4\|MS / Condition, Cell_class and T cell subcluster	MON2 HECTD3 TTC16 PHF1 FZR1 VAC14	6.30e-06	190	106	6	8c831c4560b8e70f92b4c15644fea39f7f7afcf2
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HIVEP2 NEDD4L BRINP1 ERC2 PLEKHA5 RIMS1	7.30e-06	195	106	6	2e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCell	Adult-Mesenchymal-chondrocyte\|Adult / Lineage, Cell type, age group and donor	SGIP1 NHSL2 LAMA2 KCNH2 CYSRT1	3.93e-05	159	106	5	3f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCell	ICU-SEP-Lymphocyte-T_NK-MAIT\|ICU-SEP / Disease, Lineage and Cell Type	FOXM1 CEP72 SCRIB MAB21L1 TRMT12	4.56e-05	164	106	5	db863a44fc0dad5518c47fdbf64ea21d6f36f089
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXM1 HIVEP2 GDF15 NPHP4 RSBN1	5.87e-05	173	106	5	a5172dee859bf6c2eed46c48bd64dfef0ff9f28f
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXM1 HIVEP2 GDF15 NPHP4 RSBN1	5.87e-05	173	106	5	639b5b0b33ce5aa0bc26363c059717012ddc14c0
ToppCell	E18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NEDD4L HECTD3 SRGAP1 ABCC10 TRMT12	6.20e-05	175	106	5	711ace94fa9a763c6ae48171a690953f25deebe4
ToppCell	5'-Adult-Appendix-Mesenchymal-myocytic-myofibroblast\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBN2 PLPPR4 KCNH2 PLEKHA5 RGS17	6.55e-05	177	106	5	e65c0568dc5852108e9802273499bc7cf88fafab
ToppCell	droplet-Lung-nan-3m-Myeloid-Proliferating_Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPHP4 PRAG1 CEP72 CDC25A DNA2	6.72e-05	178	106	5	de6cd81e6d58e7687386df163471bf1901b9c0aa
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_3\|368C / Donor, Lineage, Cell class and subclass (all cells)	GDF15 APLP1 RFNG NPHP4 WDFY4	6.72e-05	178	106	5	536a601abcc60867949ea06e9aafb6c7b799b56b
ToppCell	wk_20-22-Hematologic-Myeloid-aDC_1\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	WDFY4 VAC14 SLC12A3 PPP1R1C ERC2	6.72e-05	178	106	5	fd2bdb4796e86c8cff2d25f0c730ffea21db8787
ToppCell	Epithelial-lung_neuroendocrine_cell_(PNEC)\|World / Lineage, Cell type, age group and donor	KCNH6 DACH2 KCNH2 RGS17 RIMS1	7.47e-05	182	106	5	57bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	LAMA2 PLPPR4 DACH2 KCNH2 RIMS1	7.66e-05	183	106	5	e84539978ab4de42e19186aed00f24bb50cbc21f
ToppCell	Control-Epithelial-Club\|Epithelial / Disease state, Lineage and Cell class	NEDD4L GDF15 SRGAP1 RGS17 RIMS1	8.06e-05	185	106	5	6814b3c94c7558443c038a227b5c8563d2cfeac4
ToppCell	facs-Brain_Non-Myeloid-Cerebellum\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAB21L2 WDFY4 KCNH2 RIMS1 MAB21L1	8.06e-05	185	106	5	c083a4974590b9ed3ecafedd3e9cdebc5047fe39
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMA2 DAG1 APLP1 PPP1R1C MAB21L1	8.27e-05	186	106	5	6f88b68735d0f7c9904eb8413e6007910d556185
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-Granular_Neuron_CB_Gabra6\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARMIL2 PLK5 MAB21L2 KCNH2 MAB21L1	8.27e-05	186	106	5	d6c8ce2a32c218dcc63d861cc247152430ed3c8c
ToppCell	15-Airway-Epithelial-Neuroendocrine\|Airway / Age, Tissue, Lineage and Cell class	APLP1 KCNH6 LLGL2 KCNH2 RGS17	8.48e-05	187	106	5	a7d2f30fe0f19e63d44603ece9890acd11b45e52
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FOXM1 WDFY4 KIF14 TGM7 VAV1	8.48e-05	187	106	5	73931a5ea73799095daff100b5f18853c57c74dc
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	KCNH6 DACH2 KCNH2 RGS17 RIMS1	8.70e-05	188	106	5	c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	LAMA2 PLPPR4 DACH2 KCNH2 RIMS1	8.92e-05	189	106	5	b6d5dec55bf352f6ae19d8f488ae70aa10fb9a8f
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	LAMA2 PLPPR4 DACH2 KCNH2 RIMS1	8.92e-05	189	106	5	f75cebd4c3e54e297557449ba67ccc8d1a2a14f5
ToppCell	kidney_cells-Adult_normal_reference-Immune-Lymphocytic_T/NK-Cycling_Natural_Killer_Cell_/_Natural_Killer_T_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FOXM1 TTC16 KIF14 CDC25A VAV1	9.14e-05	190	106	5	b65383e256b04122500b742caeed0b807793851e
ToppCell	kidney_cells-Adult_normal_reference-Immune-Lymphocytic_T/NK-Cycling_Natural_Killer_Cell_/_Natural_Killer_T_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FOXM1 TTC16 KIF14 CDC25A VAV1	9.14e-05	190	106	5	89095d3e023269d89c82e3a73550f869e3f34201
ToppCell	PCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	FOXM1 IRX3 PPP1R1C KIF14 ERC2	9.37e-05	191	106	5	39220f4a345e328f7fa4fd462a0abeea821b3e02
ToppCell	E15.5-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	NEDD4L MAOA DAG1 IRX3 FBN2	9.37e-05	191	106	5	402c341b00f98e8215458766b3c219fff8dcb447
ToppCell	cellseq-Epithelial-Epithelial_Neuro-Secretory-PNEC-PNEC\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	APLP1 KCNH6 DACH2 KCNH2 RGS17	9.37e-05	191	106	5	146cfd4daa2878536b4f381564c787919ad855a8
ToppCell	cellseq-Epithelial-Epithelial_Neuro-Secretory-PNEC\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	APLP1 KCNH6 DACH2 KCNH2 RGS17	9.37e-05	191	106	5	12ea07565dc0e62cade9fbab4a2d763e47a341e3
ToppCell	Thalamus-Neuronal\|Thalamus / BrainAtlas - Mouse McCarroll V32	CARMIL2 KCNH2 ERC2 RGS17 RIMS1	9.84e-05	193	106	5	712a4acd1167e43543950bc819ff11984e6f718d
ToppCell	cellseq-Epithelial-Epithelial_Neuro-Secretory\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	APLP1 KCNH6 DACH2 KCNH2 RGS17	9.84e-05	193	106	5	25b1e5a04724023918c8939109a92b35582d5e5c
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	FOXM1 PRAG1 PLPPR4 DACH2 DNA2	1.01e-04	194	106	5	590a9d4f054e6a3685daf752c9354650fcc7d18a
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	LAMA2 PRAG1 PLPPR4 DACH2 RIMS1	1.01e-04	194	106	5	fb80a0271ccb1cb3f954ebcf2c5945cb6adb6b8c
ToppCell	COVID-19-Fibroblasts-Alveolar_FB\|COVID-19 / group, cell type (main and fine annotations)	SGIP1 NHSL2 LAMA2 SRGAP1 PLEKHA5	1.03e-04	195	106	5	603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-midbrain/hindbrain_cells\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	TNIK APLP1 IRX3 MAB21L2 MAB21L1	1.06e-04	196	106	5	0767581b69bc7e6334d580ca02ed1e831b7b55da
ToppCell	Bronchial-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	HECTD3 P3H3 PLK5 LAMA2 MAB21L1	1.08e-04	197	106	5	6806ec223e542f0475303698eb78c1cc527f5c6b
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GIT1 NOB1 RFNG CIAO3 SCRIB	1.11e-04	198	106	5	dd0465b45b02cb8edf0914d19afb52fcaaeb012c
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HIVEP2 BRINP1 ERC2 PLEKHA5 RIMS1	1.11e-04	198	106	5	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	Biopsy_Other_PF-Immune-Mast_cells\|Biopsy_Other_PF / Sample group, Lineage and Cell type	TNIK KCNH2 RGS17 ATP1A4 MAB21L1	1.11e-04	198	106	5	9f015553598d4c6774b2f9759e8c0f0f93e51c67
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	APLP1 BRINP1 DACH2 SRGAP1 RGS17	1.14e-04	199	106	5	0cd3e4e0fba000c996feaf012ff32198e1048c9d
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-DC-DC3-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DCST1 WDFY4 LLGL2 SLC12A3 EIF2AK4	1.14e-04	199	106	5	7271dbeca9aa838b88ad44d00059263a29c0316b
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3_mon-Neuronal\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	HIVEP2 APLP1 BRINP1 SRGAP1 RGS17	1.14e-04	199	106	5	1029f3458b7fda464aa0e7ef06e081e2618c1388
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3_mon-Neuronal-PNs\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	HIVEP2 APLP1 BRINP1 SRGAP1 RGS17	1.14e-04	199	106	5	8a04398653a1794921d73a6a950c1fb6fdf68c85
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_\|World / Primary Cells by Cluster	TNIK HIVEP2 APLP1 SRGAP1 RGS17	1.14e-04	199	106	5	058373b4ac3cec2108cb24265628ff0a50646e33
ToppCell	Sigmoid-T_cell-cycling_gd_T\|T_cell / Region, Cell class and subclass	FOXM1 DAG1 KIF14 RGS17 DNA2	1.16e-04	200	106	5	4e489ecf472857357d45e9f6c7a812aa48b72ebf
ToppCell	Bronchial-10x5prime-Immune_Myeloid-Mast_cell\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TNIK KCNH2 RGS17 ATP1A4 MAB21L1	1.16e-04	200	106	5	96540be0e906bbc626049a41978be3dc051d2024
ToppCell	Parenchymal-10x5prime-Immune_Myeloid-Mast_cell-Mast_cell\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TNIK KCNH2 RGS17 ATP1A4 MAB21L1	1.16e-04	200	106	5	8943278190f42016ee914e584d1b6b9aeaf7c73f
ToppCell	Bronchial-10x5prime-Immune_Myeloid-Mast_cell-Mast_cell\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TNIK KCNH2 RGS17 ATP1A4 MAB21L1	1.16e-04	200	106	5	41d7736427494cb30a2f23722ea2b86ff308cfd8
ToppCell	Sigmoid-(1)_T_cell-(18)_cycling_gd_T\|Sigmoid / shred on region, Cell_type, and subtype	FOXM1 DAG1 KIF14 RGS17 DNA2	1.16e-04	200	106	5	6e367abd1a4b87e20eb9095b8337723163e8bbae
ToppCell	Sigmoid-T_cell-cycling_gd_T\|Sigmoid / Region, Cell class and subclass	FOXM1 DAG1 KIF14 RGS17 DNA2	1.16e-04	200	106	5	9769185abae084ffac36420c749625e679b70ca8
ToppCell	Parenchymal-10x5prime-Immune_Myeloid-Mast_cell\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TNIK KCNH2 RGS17 ATP1A4 MAB21L1	1.16e-04	200	106	5	ea52df18400550b65de142d03b3b0963436e03d9
Drug	Epivincamine [6835-99-0]; Up 200; 11.2uM; HL60; HG-U133A	MAOA GIT1 HECTD3 LAMA2 FBXL15 NPHP4 PHF1 SLC12A3	2.47e-06	194	101	8	1783_UP
Disease	aflatoxins-related hepatocellular carcinoma (biomarker_via_orthology)	GGTLC2 GGT1 GGT3P	1.35e-06	7	101	3	DOID:5022 (biomarker_via_orthology)
Disease	alcohol dependence (biomarker_via_orthology)	GGTLC2 GGT1 GGT3P	2.15e-06	8	101	3	DOID:0050741 (biomarker_via_orthology)
Disease	gamma-glutamylglutamate measurement	GGT1 EIF2AK4 ABCC10	1.38e-05	14	101	3	EFO_0021137
Disease	epilepsy (implicated_via_orthology)	TNIK KCNH6 SLC12A3 KCNH2 ATP1A4 MAP4K4	2.13e-05	163	101	6	DOID:1826 (implicated_via_orthology)
Disease	short QT syndrome (implicated_via_orthology)	KCNH6 KCNH2	3.47e-05	3	101	2	DOID:0050793 (implicated_via_orthology)
Disease	juvenile idiopathic arthritis	LAMA2 NPHP4 RSBN1 PPP1R1C	1.24e-04	74	101	4	EFO_0002609
Disease	Congenital muscular dystrophy (disorder)	LAMA2 DAG1	1.72e-04	6	101	2	C0699743
Disease	growth differentiation factor 15 measurement	GDF15 WDFY4	2.41e-04	7	101	2	EFO_0009181
Disease	gamma-glutamylisoleucine measurement	LAMA2 GGT1	4.11e-04	9	101	2	EFO_0021139
Disease	long QT syndrome (implicated_via_orthology)	KCNH6 KCNH2	5.13e-04	10	101	2	DOID:2843 (implicated_via_orthology)
Disease	kidney cancer (implicated_via_orthology)	LLGL2 SCRIB	6.25e-04	11	101	2	DOID:263 (implicated_via_orthology)
Disease	TPE interval measurement	SGIP1 PRAG1 KCNH2	7.62e-04	52	101	3	EFO_0004644
Disease	Cakut	TRAP1 SRGAP1	8.83e-04	13	101	2	C1968949
Disease	protein-glutamine gamma-glutamyltransferase e measurement	NEDD4L GGT1 PXN	1.16e-03	60	101	3	EFO_0020690
Disease	plasma protease C1 inhibitor measurement	UBE2L6 ZDHHC5	1.53e-03	17	101	2	EFO_0008261
Disease	Antihypertensive use measurement	HIVEP2 NEDD4L PPP1R1C CDC25A ABCC10	2.21e-03	265	101	5	EFO_0009927
Disease	muscular dystrophy (implicated_via_orthology)	LAMA2 DAG1	2.33e-03	21	101	2	DOID:9884 (implicated_via_orthology)
Disease	diaphragmatic hernia	PHF1 ERC2	2.33e-03	21	101	2	EFO_0008561
Disease	airway responsiveness measurement	WDFY4 RPTOR	3.05e-03	24	101	2	EFO_0006897
Disease	apolipoprotein L1 measurement	CPN2 TLE7	3.31e-03	25	101	2	EFO_0021854

Protein segments in the cluster

Peptide	Gene	Start	Entry
QLQALPRRLFQPLTH	CPN2	156	P22792
PLLLPRNRQIYEHNE	EIF2AK4	1086	Q9P2K8
SIPRAHLRPDLGQQL	CYSRT1	16	A8MQ03
RHNPNHQLPRERTIQ	BRINP1	371	O60477
DQLQAPAERPLRLQR	CARMIL2	1366	Q6F5E8
ATDPQQLLRLIPHVQ	ATP13A1	821	Q9HD20
LLDQNPHLAQELRPQ	APLP1	466	P51693
PHLAQELRPQIQELL	APLP1	471	P51693
IHKLQAENLQLRQPP	GIT1	461	Q9Y2X7
HLLPKLQQLDDRPVR	CEP72	126	Q9P209
PLQQNHLLTNRLDLP	DACH2	301	Q96NX9
NLNPHVIRNPDVERL	CHD1	1516	O14646
QRVQDPPLQLRDAVL	GMEB2	266	Q9UKD1
HIQEPRARQVALLPV	MROH7	756	Q68CQ1
DPANLNRLRPHLELL	RC3H1	346	Q5TC82
NRLRPHLELLANIDP	RC3H1	351	Q5TC82
REVINRNLLDPNPHM	RGS17	156	Q9UGC6
HLENLQRLPPDTLLQ	RFNG	261	Q9Y644
VPDFLPNQLRRLHEA	P3H3	311	Q8IVL6
RPRQQDPQRNALLHM	FAM90A7	106	A6NKC0
ENAFPVLIQLLRNHP	ANKAR	1081	Q7Z5J8
IHFRPELPAERNQLI	MAOA	281	P21397
RAVEEPRLHNKLLPN	GGT3P	496	A6NGU5
LRQPQDICRLPHRLQ	ABCC10	241	Q5T3U5
HPFIRDQPNERQVRI	MAP4K4	286	O95819
ENGQRKQPLRVREHP	KIF14	511	Q15058
RNPLPNIDHELQELL	NOB1	161	Q9ULX3
INPHLTEDQRFPQLR	NOB1	336	Q9ULX3
NRRLLPDAPNALHIL	PIP5KL1	321	Q5T9C9
VEALQEHPRDPNQIL	LLGL2	191	Q6P1M3
LRELLRDQAHLQPLP	ELF4	566	Q99607
LRNLENEQPVHLLRP	NFKBID	276	Q8NI38
REFIRFHQIPNPLRQ	KCNH2	681	Q12809
IRFHQIPNPLRQRLE	KCNH6	536	Q9H252
DNPRDLQLLRHDLPL	DDX56	466	Q9NY93
GEPNQRPELKNHIDR	DAG1	491	Q14118
ERERHQQRPCVLPLN	DCSTAMP	256	Q9H295
ANARRLIVHLLAPNP	PLK5	36	Q496M5
RAVEEPRLHNQLLPN	GGTLC2	146	Q14390
HLLSPQRAPERLIQL	LAMA2	1621	P24043
ARPQLELHLRPQAAR	GDF15	176	Q99988
LREELHRRSQLQPEP	ERC2	356	O15083
HDPPLSQNQRLQLLL	MON2	851	Q7Z3U7
VNDHAPRFPRQQLDL	PCDHGC4	126	Q9Y5F7
LRNADTLPRLPNAAH	DPRX	101	A6NFQ7
RRLSLSHNPIEAIQP	LRRC70	231	Q7Z2Q7
PLPLPLRIQNDLHRQ	LRRC8B	86	Q6P9F7
ALLHPLLQDPAEQNR	NPHP4	161	O75161
NVPLQRSLDEIHPTR	RIMS1	971	Q86UR5
DRLLLELNAVQHNPP	PXN	146	P49023
PPLQSERRLQGHRQE	FZR1	301	Q9UM11
RQHEAPSNRPLNELL	ARAF	166	P10398
QPDRRQLLNAITHPE	DCAKD	76	Q8WVC6
RERQQKAPRHPLADI	DCST1	616	Q5T197
ANDPHDPIVNRLLRS	DIS3L	746	Q8TF46
RNQRLRQEPHYLLPA	GPR148	76	Q8TDV2
PQRPRILVQLSVHDA	DENND4C	361	Q5VZ89
RKLALQLHPDRNPDD	DNAJB11	46	Q9UBS4
PSRAQLQLHLPANRL	ESAM	26	Q96AP7
TLRDRHLELPGQPLN	MAB21L2	256	Q9Y586
EHLESQQKRPNPELR	FOXM1	336	Q08050
EPTLLALQRPQRLHH	HDAC7	16	Q8WUI4
EHILELRPAIQPLNN	FBN2	2816	P35556
GDHQQLPPLVLNREA	DNA2	786	P51530
RLPQLDHPNLIQRKA	FAM166A	201	Q6J272
LNLSHNQLRVLPPEV	LRRC30	76	A6NM36
ENLENPMRRIHSLPQ	CDC25A	96	P30304
VPRRPQNHLDAALVL	IRX3	481	P78415
QPEPQEQRERAHLQR	PHF1	396	O43189
EARQAPRPNNLHTLC	NRN1L	101	Q496H8
VQRLQLDLHEPPVSQ	RSBN1	631	Q5VWQ0
QLLSHRLQCVPNPEL	VAC14	711	Q08AM6
RPLLLNSVLLRQNPH	XAB2	341	Q9HCS7
HIQLPRNDLDPRVLS	TNRC6C	431	Q9HCJ0
DILLLNRQPTLHRPS	POLR1A	546	O95602
PLHNVALRSSEPQIR	SRGAP1	1011	Q7Z6B7
TLRDRHLELPGQPLN	MAB21L1	256	Q13394
RNPPQQLAELRDVSH	NHSL2	16	Q5HYW2
LEPLINPERHDRRLN	FAM183A	96	A6NL82
QLEIRNSPLFIHIPN	PKDREJ	281	Q9NTG1
DVLLPHVLNRVPLRQ	FBXL15	26	Q9H469
RRPTPASLVILNEHN	PPP1R1C	31	Q8WVI7
RPRQQDPQRKALLHI	FAM90A26	106	D6RGX4
LEPREVPLLHQQQGQ	PPP1R32	146	Q7Z5V6
VPLLHQQQGQDPLER	PPP1R32	151	Q7Z5V6
NLNVDRNHLEALPPE	SCRIB	316	Q14160
ICLEQLNDPHPLLRQ	RPTOR	561	Q8N122
RVLHQVTPNRDPQNR	B3GALT9	211	A8MXE2
LPRNPKTDNLVNHRL	ATP1A4	841	Q13733
LQAPDRPSRELLQHV	CIAO3	406	Q9H6Q4
VRVEAHPENNRPIIQ	PLPPR4	621	Q7Z2D5
HPFIRDQPNERQVRI	TNIK	286	Q9UKE5
GVPPLQERRHLLQEA	SEC16A	2006	O15027
INFSRLEHVLPNPQL	SGIP1	616	Q9BQI5
LPHAINLREVNLRPQ	VAV1	51	P15498
EALNVLVNRPNIREP	UBE2L6	106	O14933
RPRQQDPQRKALLHI	FAM90A2P	106	Q658T7
HLLEILQSPREGPRN	WDFY4	1486	Q6ZS81
PRAQLDLQHPQDRVV	TLE7	196	A0A1W2PR48
HEVHILPDINQNPRA	SLC12A3	891	P55017
LLRLARQDPQLHPED	MRPL28	166	Q13084
HQPNPFEVRAQLRER	PRAG1	1266	Q86YV5
LAQQREAERHPRLVP	ZDHHC5	506	Q9C0B5
QLLQPTLEINPRHAL	TRAP1	636	Q12931
QRAPEQLLALTPLHQ	STRCP1	1286	A6NGW2
LPEQHLQELRNRVAP	TRMT12	66	Q53H54
LQRINRAIENNPLDP	TTC16	271	Q8NEE8
RLPQGQARALHLLPE	PRR30	301	Q53SZ7
NNIPNHRVLIKPEIQ	PLEKHA5	291	Q9HAU0
RDQPAQLQLHLARIP	TGM7	486	Q96PF1
TQPRLVRQHNIQVPE	HIVEP2	876	P31629
ELQLAAAPQRPAVRH	TTC22	56	Q5TAA0
KRAVEEPRLHNQLLP	GGT1	496	P19440
RLVPIDTPNHLQRQQ	HECTD3	151	Q5T447
NSNNHLIEPQIRRPR	NEDD4L	431	Q96PU5