Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmicrofilament motor activity

MYH1 MYH2 MYH4 MYH8 MYO1D MYO19

5.79e-07381626GO:0000146
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYH1 MYH2 MYH4 MYH8 MYO1D MYO19 KIF13A

5.04e-051181627GO:0003774
GeneOntologyMolecularFunctionGTP-dependent protein kinase activity

LRRK2 BRD4

6.54e-0521622GO:0034211
GeneOntologyMolecularFunctioncytoskeletal protein binding

MAGI1 MYH1 MYH2 MYH4 MYH8 MYO1D SYNE1 MYO19 LRRK2 TUBGCP2 OPHN1 WASH6P WASH3P PTPN4 CCDC66 BRCA1 CLTC CCSER2 FES KIF13A MX2

2.27e-04109916221GO:0008092
GeneOntologyMolecularFunctionATP-dependent activity

ACSL6 MYH1 MYH2 MYH4 MYH8 MYO1D ZGRF1 MYO19 MCM2 FANCM DDX46 KIF13A ACSM6 ACSL5

4.94e-0461416214GO:0140657
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

CCNL2 DRC1 NCKAP5 TUBGCP2 TBC1D32 WASH6P NCOR1 WASH3P CCDC66 AUNIP AKAP9 BRCA1 CCNL1 CLTC CCSER2 FES OCLN ZMYND12

1.51e-0572016218GO:0000226
GeneOntologyCellularComponentmuscle myosin complex

MYH1 MYH2 MYH4 MYH8

6.18e-06161644GO:0005859
GeneOntologyCellularComponentmyosin complex

MYH1 MYH2 MYH4 MYH8 MYO1D MYO19

6.80e-06591646GO:0016459
GeneOntologyCellularComponentmyosin filament

MYH1 MYH2 MYH4 MYH8

4.06e-05251644GO:0032982
GeneOntologyCellularComponentmyosin II complex

MYH1 MYH2 MYH4 MYH8

6.46e-05281644GO:0016460
GeneOntologyCellularComponentspecific granule lumen

DOCK2 ERP44 CHIT1 PDXK LRRC7

1.26e-04621645GO:0035580
GeneOntologyCellularComponentRQC complex

NEMF LTN1

1.83e-0431642GO:1990112
GeneOntologyCellularComponentBRCA1-B complex

TOPBP1 BRCA1

3.63e-0441642GO:0070532
GeneOntologyCellularComponentactin cytoskeleton

MYH1 MYH2 MYH4 MYH8 MYO1D MYO19 TOPBP1 ANKRD62 ARHGAP35 OPHN1 RAPGEF3 CD274 LRRC7

6.36e-0457616413GO:0015629
DomainMyosin_head_motor_dom

MYH1 MYH2 MYH4 MYH8 MYO1D MYO19

6.33e-07381546IPR001609
DomainMYOSIN_MOTOR

MYH1 MYH2 MYH4 MYH8 MYO1D MYO19

6.33e-07381546PS51456
DomainMyosin_head

MYH1 MYH2 MYH4 MYH8 MYO1D MYO19

6.33e-07381546PF00063
DomainMYSc

MYH1 MYH2 MYH4 MYH8 MYO1D MYO19

6.33e-07381546SM00242
DomainIQ

MYH1 MYH2 MYH4 MYH8 MYO1D MYO19 INVS

4.72e-06811547SM00015
DomainMyosin_N

MYH1 MYH2 MYH4 MYH8

5.65e-06151544PF02736
DomainMyosin_N

MYH1 MYH2 MYH4 MYH8

5.65e-06151544IPR004009
DomainIQ_motif_EF-hand-BS

MYH1 MYH2 MYH4 MYH8 MYO1D MYO19 INVS

9.52e-06901547IPR000048
DomainIQ

MYH1 MYH2 MYH4 MYH8 MYO1D MYO19 INVS

1.18e-05931547PS50096
DomainMyosin_tail_1

MYH1 MYH2 MYH4 MYH8

1.24e-05181544PF01576
DomainMyosin_tail

MYH1 MYH2 MYH4 MYH8

1.24e-05181544IPR002928
DomainMyosin-like_IQ_dom

MYH1 MYH2 MYH4 MYH8

1.56e-05191544IPR027401
Domain-

MYH1 MYH2 MYH4 MYH8

1.56e-051915444.10.270.10
DomainIQ

MYH1 MYH2 MYH4 MYH8 MYO1D INVS

2.62e-05711546PF00612
DomainPhosphofurin_acidic_CS-1

PACS1 PACS2

6.75e-0521542IPR019381
DomainPacs-1

PACS1 PACS2

6.75e-0521542PF10254
DomainP-loop_NTPase

MAGI1 MYH1 MYH2 MYH4 MYH8 MYO1D ZGRF1 MYO19 LRRK2 MCM2 ARHGAP35 FANCM RAB28 DDX46 DLG3 COASY KIF13A MX2

2.22e-0484815418IPR027417
Pubmed

Developmental pattern of mouse skeletal myosin heavy chain gene transcripts in vivo and in vitro.

MYH1 MYH2 MYH4 MYH8

2.49e-09516643829126
Pubmed

Myosin heavy chain isoforms of the murine masseter muscle during pre- and post-natal development.

MYH1 MYH2 MYH4 MYH8

2.49e-095166412919077
Pubmed

Sequential accumulation of mRNAs encoding different myosin heavy chain isoforms during skeletal muscle development in vivo detected with a recombinant plasmid identified as coding for an adult fast myosin heavy chain from mouse skeletal muscle.

MYH1 MYH2 MYH4 MYH8

2.49e-09516646196357
Pubmed

Distinct myogenic programs of embryonic and fetal mouse muscle cells: expression of the perinatal myosin heavy chain isoform in vitro.

MYH1 MYH2 MYH4 MYH8

7.45e-09616641728586
Pubmed

Organization of human and mouse skeletal myosin heavy chain gene clusters is highly conserved.

MYH1 MYH2 MYH4 MYH8

7.45e-096166410077619
Pubmed

Spatial and temporal changes in myosin heavy chain gene expression in skeletal muscle development.

MYH1 MYH2 MYH4 MYH8

7.45e-096166410588881
Pubmed

A fast Myosin super enhancer dictates muscle fiber phenotype through competitive interactions with Myosin genes.

MYH1 MYH2 MYH4 MYH8

1.73e-087166435210422
Pubmed

Diversity in transcriptional start site selection and alternative splicing affects the 5'-UTR of mouse striated muscle myosin transcripts.

MYH1 MYH2 MYH4 MYH8

1.73e-087166416819597
Pubmed

Transition of myosin heavy chain isoforms in human laryngeal abductors following denervation.

MYH1 MYH2 MYH4

1.07e-073166326059207
Pubmed

Modulation of contractile protein gene expression in fetal murine crural muscles: emergence of muscle diversity.

MYH1 MYH2 MYH4 MYH8

1.61e-071116648136524
Pubmed

Contractile protein gene expression in primary myotubes of embryonic mouse hindlimb muscles.

MYH1 MYH2 MYH4 MYH8

3.46e-071316648404542
Pubmed

Evaluation of embryonic and perinatal myosin gene mutations and the etiology of congenital idiopathic clubfoot.

MYH1 MYH2 MYH8

4.26e-074166320357587
Pubmed

Three linked myosin heavy chain genes clustered within 370 kb of each other show independent transcriptional and post-transcriptional regulation during differentiation of a mouse muscle cell line.

MYH1 MYH4 MYH8

4.26e-07416631985022
Pubmed

Smooth muscle myosin light chain kinase expression in cardiac and skeletal muscle.

MYH1 MYH2 MYH4

4.26e-074166311029314
Pubmed

Modulation of skeletal muscle fiber type by mitogen-activated protein kinase signaling.

MYH1 MYH2 MYH4

4.26e-074166318417546
Pubmed

Comparative sequence analysis of the complete human sarcomeric myosin heavy chain family: implications for functional diversity.

MYH1 MYH2 MYH4

4.26e-074166310388558
Pubmed

A human YAC transgene rescues craniofacial and neural tube development in PDGFRalpha knockout mice and uncovers a role for PDGFRalpha in prenatal lung growth.

MYH1 MYH2 MYH4

4.26e-074166311023856
Pubmed

Defective excitation-contraction coupling is partially responsible for impaired contractility in hindlimb muscles of Stac3 knockout mice.

MYH1 MYH2 MYH4 MYH8

4.83e-0714166427184118
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

NCAPD3 MCM2 ARHGAP35 WTAP PACS1 NCOR1 DDX46 BRD4 CCNL1 CLTC PACS2 PLCB3 COASY BUB3 ANXA9 BAG6

1.06e-067741661615302935
Pubmed

Detection of Gene and Protein Expression in Mouse Embryos and Tissue Sections.

MYH1 MYH2 MYH4

1.06e-065166330737693
Pubmed

Characterization of the murine orthologue of a novel human subtelomeric multigene family.

WASH6P WASH3P WASH4P

1.06e-065166311701968
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

MAGI1 NCAPD3 VPS37A ERP44 POLA1 MRPL19 TUBGCP2 ARHGAP35 WTAP MRPS30 NCOR1 AKAP9 SKOR2 BUB3 IPO11

1.24e-066891661536543142
Pubmed

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

NCAPD3 RBM45 TOPBP1 FANCM DSN1 WTAP HIRA DDX46 BRCA1 DTWD2 ZNF827 BUB3

2.06e-064531661229656893
Pubmed

A hypoplastic model of skeletal muscle development displaying reduced foetal myoblast cell numbers, increased oxidative myofibres and improved specific tension capacity.

MYH1 MYH2 MYH4

2.11e-066166320417199
Pubmed

Human subtelomeric WASH genes encode a new subclass of the WASP family.

WASH6P WASH3P WASH4P

2.11e-066166318159949
Pubmed

A role for Insulin-like growth factor 2 in specification of the fast skeletal muscle fibre.

MYH1 MYH2 MYH4

2.11e-066166317559643
Pubmed

A new role for the calcineurin/NFAT pathway in neonatal myosin heavy chain expression via the NFATc2/MyoD complex during mouse myogenesis.

MYH1 MYH2 MYH4 MYH8

3.42e-0622166424301466
Pubmed

ANKK1 is found in myogenic precursors and muscle fibers subtypes with glycolytic metabolism.

MYH1 MYH2 MYH4

3.69e-067166329758057
Pubmed

WASH maintains NKp46+ ILC3 cells by promoting AHR expression.

WASH6P WASH3P RORC

3.69e-067166328589939
Pubmed

Cell lineage- and expression-based inference of the roles of forkhead box transcription factor Foxc2 in craniofacial development.

MYH1 MYH2 MYH4

5.88e-068166333667029
Pubmed

A Tcf4-positive mesodermal population provides a prepattern for vertebrate limb muscle patterning.

MYH1 MYH2 MYH4

5.88e-068166314667415
Pubmed

Neuromuscular junction immaturity and muscle atrophy are hallmarks of the ColQ-deficient mouse, a model of congenital myasthenic syndrome with acetylcholinesterase deficiency.

MYH1 MYH2 MYH4

5.88e-068166326993635
Pubmed

Genes for skeletal muscle myosin heavy chains are clustered and are not located on the same mouse chromosome as a cardiac myosin heavy chain gene.

MYH1 MYH4 MYH8

5.88e-06816633864153
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

NCAPD3 WDR33 POLA1 TUBGCP2 HIRA NCOR1 DDX46 FDPS TRMT5 IPO11

6.19e-063411661032971831
Pubmed

GASP-2 overexpressing mice exhibit a hypermuscular phenotype with contrasting molecular effects compared to GASP-1 transgenics.

MYH1 MYH2 MYH4

8.78e-069166331960486
Pubmed

Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

TCAF1 MYO1D SYNE1 DDX46 AKAP9 LTN1

9.41e-0610116669872452
Pubmed

The E3 ubiquitin ligase UBR5 interacts with the H/ACA ribonucleoprotein complex and regulates ribosomal RNA biogenesis in embryonic stem cells.

CCNL2 NHP2 DDX46 CCNL1 BUB3 IPO11

1.11e-05104166631365120
Pubmed

During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation.

MYH1 MYH4 MYH8

1.25e-0510166319506036
Pubmed

Acceleration of somitic myogenesis in embryos of myogenin promoter-MRF4 transgenic mice.

MYH1 MYH2 MYH8

1.25e-051016638950513
Pubmed

Placing the HIRA histone chaperone complex in the chromatin landscape.

MCM2 E2F6 POLR3A HIRA

1.42e-0531166423602572
Pubmed

Deletion of the protein kinase A/protein kinase G target SMTNL1 promotes an exercise-adapted phenotype in vascular smooth muscle.

MYH1 MYH2 MYH4

1.71e-0511166318310078
Pubmed

Calcineurin is necessary for the maintenance but not embryonic development of slow muscle fibers.

MYH1 MYH2 MYH4

1.71e-0511166316024798
Pubmed

Extracellular matrix protein composition dynamically changes during murine forelimb development.

MYH1 MYH2 MYH4

1.71e-0511166338303699
Pubmed

The histone code reader Spin1 controls skeletal muscle development.

MYH1 MYH2 MYH4

1.71e-0511166329168801
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

ZGRF1 SYNE1 FAT3 LAMA1 OTOF CLTC ANXA9 KIF13A

1.80e-05234166836243803
Pubmed

Myosin heavy chain-embryonic regulates skeletal muscle differentiation during mammalian development.

MYH1 MYH2 MYH4 MYH8

1.84e-0533166432094117
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

ZSWIM8 DOCK11 TUBGCP2 OPHN1 WASH6P NCOR1 WASH3P DDX46 NEMF SMU1 PLCB3

1.94e-054751661131040226
Pubmed

Direct interaction with the BRD4 carboxyl-terminal motif (CTM) and TopBP1 is required for human papillomavirus 16 E2 association with mitotic chromatin and plasmid segregation function.

TOPBP1 BRD4

2.26e-052166237712702
Pubmed

Myosin heavy chains IIa and IId are functionally distinct in the mouse.

MYH1 MYH2

2.26e-05216629585413
Pubmed

Expression and clinical value of PD-L1 which is regulated by BRD4 in tongue squamous cell carcinoma.

BRD4 CD274

2.26e-052166231633227
Pubmed

Structure and assembly pathway of the ribosome quality control complex.

NEMF LTN1

2.26e-052166225578875
Pubmed

Differential effects of testosterone and TGF-β3 on endocytic vesicle-mediated protein trafficking events at the blood-testis barrier.

CLTC OCLN

2.26e-052166220682309
Pubmed

Analysis of mouse conceptuses with uniparental duplication/deficiency for distal chromosome 12: comparison with chromosome 12 uniparental disomy and implications for genomic imprinting.

MYH1 MYH2

2.26e-052166216575183
Pubmed

Both DNA topoisomerase II-binding protein 1 and BRCA1 regulate the G2-M cell cycle checkpoint.

TOPBP1 BRCA1

2.26e-052166212810625
Pubmed

The BRCA1 Methylation and PD-L1 Expression in Sporadic Ovarian Cancer.

BRCA1 CD274

2.26e-052166230045136
Pubmed

Growth and muscle defects in mice lacking adult myosin heavy chain genes.

MYH1 MYH4

2.26e-05216629382868
Pubmed

Postnatal myosin heavy chain isoform expression in normal mice and mice null for IIb or IId myosin heavy chains.

MYH1 MYH4

2.26e-052166211150240
Pubmed

Myosin heavy chain composition of the human genioglossus muscle.

MYH1 MYH2

2.26e-052166222337492
Pubmed

Sox11 regulates mammary tumour-initiating and metastatic capacity in Brca1-deficient mouse mammary tumour cells.

SOX11 BRCA1

2.26e-052166233969421
Pubmed

Induction of tight junctions in human connexin 32 (hCx32)-transfected mouse hepatocytes: connexin 32 interacts with occludin.

GJB1 OCLN

2.26e-052166210581193
Pubmed

AKAP9 regulation of microtubule dynamics promotes Epac1-induced endothelial barrier properties.

AKAP9 RAPGEF3

2.26e-052166220952690
Pubmed

E2F6 negatively regulates BRCA1 in human cancer cells without methylation of histone H3 on lysine 9.

E2F6 BRCA1

2.26e-052166212909625
Pubmed

An interdomain binding site on HIV-1 Nef interacts with PACS-1 and PACS-2 on endosomes to down-regulate MHC-I.

PACS1 PACS2

2.26e-052166222496420
Pubmed

Different pathways regulate expression of the skeletal myosin heavy chain genes.

MYH1 MYH2

2.26e-052166211551968
Pubmed

Caught in the act - protein adaptation and the expanding roles of the PACS proteins in tissue homeostasis and disease.

PACS1 PACS2

2.26e-052166228476937
Pubmed

High-Level Expression and Prognostic Significance of Matrix Metalloprotease-19 and Matrix Metalloprotease-20 in Human Pancreatic Ductal Adenocarcinoma.

MMP20 MMP19

2.26e-052166226692439
Pubmed

Tight junction protein MAGI-1 is up-regulated by transfection with connexin 32 in an immortalized mouse hepatic cell line: cDNA microarray analysis.

MAGI1 GJB1

2.26e-052166215558322
Pubmed

Evidence supporting a role for TopBP1 and Brd4 in the initiation but not continuation of human papillomavirus 16 E1/E2-mediated DNA replication.

TOPBP1 BRD4

2.26e-052166225694599
Pubmed

Five skeletal myosin heavy chain genes are organized as a multigene complex in the human genome.

MYH4 MYH8

2.26e-05216628518795
Pubmed

Type IIx myosin heavy chain transcripts are expressed in type IIb fibers of human skeletal muscle.

MYH1 MYH2

2.26e-05216627545970
Pubmed

BRD4 inhibition suppresses PD-L1 expression in triple-negative breast cancer.

BRD4 CD274

2.26e-052166232339606
Pubmed

Temporal spatial expression and function of non-muscle myosin II isoforms IIA and IIB in scar remodeling.

MYH2 MYH4

2.26e-052166221102503
Pubmed

FANCM regulates repair pathway choice at stalled replication forks.

FANCM BRCA1

2.26e-052166233882298
Pubmed

Skeletal muscle adaptations in response to voluntary wheel running in myosin heavy chain null mice.

MYH1 MYH4

2.26e-052166211744674
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

MYH2 MYH4 TCAF1 ERP44 RBM45 POLA1 MCM2 TUBGCP2 NHP2 POLR3A BRCA1 SMU1 PAN2 BUB3 BAG6 CPNE7

2.77e-0510051661619615732
Pubmed

The inhibition of differentiation caused by TGFbeta in fetal myoblasts is dependent upon selective expression of PKCtheta: a possible molecular basis for myoblast diversification during limb histogenesis.

MYH1 MYH2 MYH8

2.95e-051316638948582
Pubmed

Temporal regulation of the Mediator complex during muscle proliferation, differentiation, regeneration, aging, and disease.

MYH1 MYH2 MYH4 MYH8

3.61e-0539166438690566
Pubmed

Myopathy associated LDB3 mutation causes Z-disc disassembly and protein aggregation through PKCα and TSC2-mTOR downregulation.

MYH1 MYH2 MYH4

3.74e-0514166333742095
Pubmed

Loss of Prox1 in striated muscle causes slow to fast skeletal muscle fiber conversion and dilated cardiomyopathy.

MYH1 MYH2 MYH4

3.74e-0514166324938781
Pubmed

The IgCAM CLMP regulates expression of Connexin43 and Connexin45 in intestinal and ureteral smooth muscle contraction in mice.

GJB1 CLTC OCLN

3.74e-0514166329361518
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR4N2 OR4S2 OR4C11 OR8K5 OR5AL1 OR4C3 OR5H2 OR4C5 OR10A5

4.05e-05340166911875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR4N2 OR4S2 OR4C11 OR8K5 OR5AL1 OR4C3 OR5H2 OR4C5 OR10A5

4.05e-05340166911802173
Pubmed

A Y2H-seq approach defines the human protein methyltransferase interactome.

VPS37A NHP2 ZBTB24 AUNIP AKAP9 BRD4 CCNL1 BAG6 SMYD3

4.24e-05342166923455924
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR4N2 OR4S2 OR4C11 OR8K5 OR5AL1 OR4C3 OR5H2 OR4C5 OR10A5

4.33e-05343166932295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR4N2 OR4S2 OR4C11 OR8K5 OR5AL1 OR4C3 OR5H2 OR4C5 OR10A5

4.63e-05346166914611657
Pubmed

Six homeoproteins and a Iinc-RNA at the fast MYH locus lock fast myofiber terminal phenotype.

MYH1 MYH2 MYH4

4.66e-0515166324852826
Pubmed

Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1.

ANGPT1 MCM2 FDPS CLTC

5.34e-054316647584026
Pubmed

MusTRD can regulate postnatal fiber-specific expression.

MYH1 MYH2 MYH4

5.71e-0516166316494860
Pubmed

A family of microRNAs encoded by myosin genes governs myosin expression and muscle performance.

MYH1 MYH2 MYH4

5.71e-0516166319922871
Pubmed

Elucidation of the Fanconi Anemia Protein Network in Meiosis and Its Function in the Regulation of Histone Modifications.

TOPBP1 FANCM BRCA1

5.71e-0516166327760317
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

ERP44 RBM45 WDR33 SYNE1 MRPL19 ARHGAP35 WTAP HIRA DDX46 BRD4 NEMF CLTC SMU1 PAN2 BUB3 ZNF292

6.64e-0510821661638697112
Pubmed

Mapping the Genetic Landscape of Human Cells.

POLA1 MRPL19 POLR3A MRPS30 DDX46 FDPS NEMF LTN1 BUB3 TRMT5

6.70e-054511661030033366
Pubmed

Many sequence variants affecting diversity of adult human height.

FRS2 ZBTB24 DDX46 GOLIM4 UQCC1 KIF13A

6.72e-05143166618391951
Pubmed

Simultaneous loss of skeletal muscle myosin heavy chain IIx and IIb causes severe skeletal muscle hypoplasia in postnatal mice.

MYH1 MYH4

6.77e-053166236515178
Pubmed

Phosphorylation of claudin-5 and occludin by rho kinase in brain endothelial cells.

GRK1 OCLN

6.77e-053166218187566
Pubmed

HIRA-mediated loading of histone variant H3.3 controls androgen-induced transcription by regulation of AR/BRD4 complex assembly at enhancers.

HIRA BRD4

6.77e-053166237638746
Pubmed

FANCM, BRCA1, and BLM cooperatively resolve the replication stress at the ALT telomeres.

FANCM BRCA1

6.77e-053166228673972
Pubmed

Molecular determinants of force production in human skeletal muscle fibers: effects of myosin isoform expression and cross-sectional area.

MYH1 MYH2

6.77e-053166225567808
Pubmed

WASH Regulates Glucose Homeostasis by Facilitating Glut2 Receptor Recycling in Pancreatic β-Cells.

WASH6P WASH3P

6.77e-053166230425062
Pubmed

BET proteins regulate homologous recombination-mediated DNA repair: BRCAness and implications for cancer therapy.

BRCA1 BRD4

6.77e-053166230259975
InteractionUBR5 interactions

CCNL2 MYH4 TOPBP1 MCM2 NHP2 DSN1 WTAP DDX46 BRCA1 BRD4 CCNL1 SMU1 BUB3 MMP19 BAG6 IPO11

4.02e-0653315616int:UBR5
InteractionRSPH6A interactions

MYH1 MYH2 MYH4 MYH8 TCAF1

6.05e-06341565int:RSPH6A
InteractionSLC39A3 interactions

MYH1 MYH2 MYH4 MYH8 NCOR1 B3GNT2

1.70e-05701566int:SLC39A3
GeneFamilyMyosin heavy chains

MYH1 MYH2 MYH4 MYH8

2.08e-061511641098
GeneFamilyWiskott-Aldrich Syndrome protein family

WASH6P WASH3P WASH4P

1.36e-0416116314
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

GPR12 MYO1D NCOR1 AKAP9 BRCA1 DLG3 OCLN

1.67e-041811167694
GeneFamilyOlfactory receptors, family 4

OR4N2 OR4S2 OR4C11 OR4C3 OR4S1 OR4C5

1.83e-041291166151
GeneFamilyAnkyrin repeat domain containing|BRCA1 B complex

TOPBP1 BRCA1

2.43e-04411621335
CoexpressionHUMMERICH_BENIGN_SKIN_TUMOR_DN

MYH1 MYH2 MYH4 MYH8

6.46e-06201634M1123
CoexpressionHUMMERICH_BENIGN_SKIN_TUMOR_DN

MYH1 MYH2 MYH4 MYH8

7.94e-06211634MM1102
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500_k-means-cluster#5

MAGI1 POLA1 FAT3 CCDC66 DDX46 AKAP9 BRCA1 LRRC1 NEMF IPO11

7.33e-0623215310Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500_K5
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

MAGI1 SOX11 TCAF1 POLA1 NCOR1 CCDC66 DDX46 AKAP9 BRCA1 NEMF ZNF292

1.64e-0531115311Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
ToppCellH1299-infected|H1299 / Cell line, Condition and Strain

CCNL2 ANKRD62 NCOR1 AKAP9 BRD4 CCNL1 RNF216 ANKRD18A CPNE7 ZNF292

2.63e-09192164109cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Grp_(Neuron.Slc17a6.Grp)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYH1 MYH2 MYH8 DSC3 SKOR2 PAH

1.48e-07651646b7bc23af54d6d2f7afd584f4df42c24d7c49e344
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Grp_(Neuron.Slc17a6.Grp)|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYH1 MYH2 MYH8 DSC3 SKOR2 PAH

1.48e-076516463b3630253f5713c4a688c74c4ea0f98c1fe42594
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NCAPD3 POLA1 ZGRF1 TOPBP1 MCM2 DSN1 AUNIP BRCA1

2.78e-07174164866555c610251ea04f968c258e312d720c18e7cde
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

RBL1 POLA1 ZGRF1 MYO19 MCM2 DSN1 AUNIP BRCA1

6.61e-071951648b65463a804fed2d9a3be9e528ca8b9c98469bc86
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

CCNL2 ANKRD62 DDX46 AKAP9 CCNL1 NEMF ANKRD18A ZNF292

7.14e-0719716480fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCellStriatum-Neuronal-Inhibitory-iN2(Gad1Gad2)-Inhibitory_Neuron.Gad1Gad2.Pnoc_(Fast-spiking_interneuron,_Pvalb+/Pnoc+)-|Striatum / BrainAtlas - Mouse McCarroll V32

MYH1 MYH8 C4orf54 ELMO3 DISP3 CPNE7

3.35e-0611016465496c92932195386025254b9129d69b12c8e3340
ToppCellStriatum-Neuronal-Inhibitory-iN2(Gad1Gad2)-Inhibitory_Neuron.Gad1Gad2.Pnoc_(Fast-spiking_interneuron,_Pvalb+/Pnoc+)--|Striatum / BrainAtlas - Mouse McCarroll V32

MYH1 MYH8 C4orf54 ELMO3 DISP3 CPNE7

3.35e-06110164641306a2d4a5a39569437eb123e47f98ef8afab24
ToppCellStriatum-Neuronal-Inhibitory-iN2(Gad1Gad2)-Inhibitory_Neuron.Gad1Gad2.Pnoc_(Fast-spiking_interneuron,_Pvalb+/Pnoc+)|Striatum / BrainAtlas - Mouse McCarroll V32

MYH1 MYH8 C4orf54 ELMO3 DISP3 CPNE7

3.35e-0611016461fe08060248b25329f73b80d74435c108bee1359
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RBL1 POLA1 RADX TOPBP1 MCM2 AUNIP BRCA1

3.68e-06173164715af4a0f7516dbf5c93ba66a19aca073ebe30d04
ToppCell356C-Lymphocytic-NK_cells-NK_cell_E|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

MYO1D SPATA21 B3GNT2 GOLIM4 POGLUT2 KIF13A CPNE7

3.68e-061731647090dc3c5bd2652a65c2490fc889da858c3af368f
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NCAPD3 RBL1 POLA1 ZGRF1 MCM2 AUNIP BRCA1

3.83e-061741647c988471207ba06195bc3e41056435e8c31c20bbe
ToppCell356C-Lymphocytic-NK_cells-NK_cell_E|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MYO1D SPATA21 B3GNT2 GOLIM4 POGLUT2 KIF13A CPNE7

3.83e-061741647a79ebb01a5849c314e02594a9c95009dbb03cb8c
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

KIAA0319L LRRK2 E2F6 DSN1 ZBTB24 SMU1 ACSL5

6.82e-061901647651a1d3ae286e40f9d9f60e438211c6148d24143
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SYNE1 SESN3 TBC1D32 AKAP9 OCLN ZNF292 BRWD1

7.55e-0619316479337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellhuman_hepatoblastoma-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

NCAPD3 RBL1 POLA1 ZGRF1 FANCM DSN1 BRCA1

7.55e-0619316474b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

RBL1 POLA1 ZGRF1 MYO19 MCM2 DSN1 BRCA1

8.08e-06195164756d8734d020b3da08a5aa9e67999706a9e023a99
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

RBL1 POLA1 ZGRF1 TOPBP1 MCM2 DSN1 BRCA1

8.35e-061961647df366d76ea55f49e349d622effa57c1535df8400
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Nonmucinous_Lepidic_Adenocarcinoma|TCGA-Lung / Sample_Type by Project: Shred V9

KIAA0319L STEAP4 DLG3 OCLN CFAP99 ACSL5

1.51e-051431646510e0410544f78ebc5bb597e87f01a00ce48b39b
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NCAPD3 MYO19 ANKRD62 CCSER2 PAN2 BRWD1

2.96e-0516116465fba13f0aa5002f7eefe219e2c6a07e163f1a50d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYH1 MYH2 MYH4 MYH8 DOCK11 LRRK2

3.28e-051641646382e42701779d12a7948690b3be72d06dd75c8b4
ToppCelldroplet-Lung-nan-21m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZGRF1 MCM2 ARHGAP35 DSN1 GRHL1 BRCA1

3.51e-05166164621ba5fd755c0fb31ada42a1b5d60bede0153323d
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCNL2 FAT3 NCKAP5 GJB1 PAH LRRC7

4.56e-051741646165e14cad57e90aa247dcecfaa3c2e8ff2a470ad
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCNL2 FAT3 NCKAP5 GJB1 PAH LRRC7

4.56e-0517416464289dfc7613db4bb3d706b9b65d06e84c0c53558
ToppCelldroplet-Lung-21m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RBL1 ZGRF1 ARHGAP35 DSN1 GRHL1 BRCA1

4.71e-0517516466751ee4b312d7f87275f2c35e5878cfc3be3ebe3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1D DOCK11 SYNE1 FAT3 SESN3 PDXK

5.02e-051771646da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

VPS37A GRIN2D RAB28 OTOF B3GNT2 CCSER2

5.18e-051781646be4976bbfd9ebbc568155ede99a07670c43aa372
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI1 MYO1D DOCK11 LRRK2 PDXK OPHN1

5.18e-051781646c20f050344a2e120e685e2a7fe36c6dfc1dc37b6
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

VPS37A GRIN2D RAB28 OTOF B3GNT2 CCSER2

5.18e-05178164691bf3c7c05d2e67ee590389a1b36c517d0ed7ebf
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX11 NCKAP5 ARHGAP35 BRCA1 POGLUT2 MPPED1

5.68e-0518116464e81ec1580e9acb22c32c465eb46f83d1e9e424e
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX11 NCKAP5 ARHGAP35 BRCA1 POGLUT2 MPPED1

5.68e-051811646ad30c01290fb98adbd0caed301a584761212c977
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX11 NCKAP5 ARHGAP35 BRCA1 POGLUT2 MPPED1

5.68e-0518116463a3268a4dff8ffcb79e09f46490e138c96f8d916
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX11 MYH1 FAT3 LAMA1 PTPRQ DISP3

6.22e-0518416462cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX11 MYH1 FAT3 LAMA1 PTPRQ DISP3

6.22e-051841646ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX11 MYH1 FAT3 LAMA1 PTPRQ DISP3

6.22e-0518416462b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellEpithelial-alveolar_epithelial_cell_type_1|World / Lineage, Cell type, age group and donor

MAGI1 MYO1D NCKAP5 LRRC1 PTPRQ OCLN

6.61e-05186164609d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX11 RBM45 RADX MCM2 BRCA1 SLITRK6

6.80e-05187164638ee33295a21db4aae5ba085df033db9693e41c6
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX11 RBM45 RADX MCM2 BRCA1 SLITRK6

6.80e-051871646dbcec24d2c852964736c78e9d81650bff5c455ae
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MAGI1 MYO1D NCKAP5 LRRC1 PTPRQ OCLN

7.01e-051881646eea652bab161f19148a883e7e3fe2523b36b3cea
ToppCellcontrol-immature_Neutrophil|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MYO19 KIAA0319L VIPAS39 PACS2 RORC ACSL5

7.22e-051891646bdfd120900ba58d5e54765f7b576e1f8cc2401bf
ToppCellPBMC-Mild-cDC_12|Mild / Compartment, Disease Groups and Clusters

RBL1 POLA1 MCM2 BRCA1 RORC POGLUT2

7.22e-051891646946c95d2ecc36b241f58e8c4ad6455fe47c762fa
ToppCellPBMC-Severe-cDC_12|Severe / Compartment, Disease Groups and Clusters

NCAPD3 RBL1 TOPBP1 MCM2 DSN1 BRCA1

7.43e-05190164684ee185939bdefb10705b621a70da27701eadcee
ToppCellnucseq-Epithelial-Epithelial_Alveolar|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MAGI1 SYNE1 LRRK2 STEAP4 NCKAP5 SMYD3

8.33e-05194164653f3e49e91b1096f3226010e2de767efb490dfe4
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

RBL1 POLA1 ZGRF1 MCM2 DSN1 BRCA1

8.57e-051951646cec7df321f372d05c94f97d6bb18891a5cc3dec3
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MAGI1 MYO1D SYNE1 LRRK2 NCKAP5 SMYD3

8.57e-0519516469406866f99555198a9be311fbd65751b70f35446
ToppCellcontrol-immature_Neutrophil|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MYO19 KIAA0319L CHIT1 PACS2 RORC ACSL5

8.82e-051961646e34fd3e7a5b1c22a81fd3208e6d58bdb846d51c4
ToppCellLPS_IL1RA_TNF|World / Treatment groups by lineage, cell group, cell type

ANGPT1 SYNE1 LRRK2 AKAP9 SPARCL1 SLITRK6

9.06e-0519716460a6550dce156fc81f15b1e7830d331ca50d87d06
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

LRRK2 STEAP4 PGM3 AKAP9 CCNL1 ACSL5

9.32e-051981646285f729140b1df029c24f6ca1d2438470ac51794
ToppCellAT2_cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

MAGI1 SYNE1 LRRK2 STEAP4 FDPS OCLN

9.32e-0519816468a1f984e46f4fa5be33027b9dbaa2ca060a2245d
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

MAGI1 MYO1D OPHN1 PTPRG KIF13A SMYD3

9.32e-0519816461996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-35|World / Primary Cells by Cluster

SOX11 TCAF1 PTPN4 AKAP9 LRRC7 ZNF292

9.32e-051981646de5214a85fe017eb23d4aa8af624464f062ec57e
ToppCell(02)_MMP9/10+-(2)_GFP_FOXI1|(02)_MMP9/10+ / shred by cell type by condition

FAT3 SESN3 AKAP9 BRD4 CCSER2 GOLIM4

9.58e-05199164618a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

STEAP4 NCOR1 AKAP9 BRD4 ZNF292 BRWD1

9.58e-051991646c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCellmild-T/NK_proliferative|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

NCAPD3 RBL1 POLA1 TOPBP1 MCM2 BRCA1

9.85e-05200164663cc57b9331459efbb73051d174d198a3568b938
ToppCellSepsis-ICU-NoSEP-Lymphocyte-T/NK-MAIT|ICU-NoSEP / Disease, condition lineage and cell class

CCNL2 POLA1 ELMO3 RORC OCLN CPNE7

9.85e-0520016464f03b5f4110ed1637ffe17cb6ff309265a3af9a8
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Htr1a_(Neuron.Slc17a6.Htr1a)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYH1 MYH2 ASB14 OTOF

1.09e-04671644be6853b5bf254063f02a4c478fd4c3fef68cb77a
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Htr1a_(Neuron.Slc17a6.Htr1a)|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYH1 MYH2 ASB14 OTOF

1.09e-046716447483b85423d9d07b01b60927d0fe1b7ccb241d7f
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Bcl11b-Inhibitory_Gad1Gad2_Id2.Bcl11b_(Interneuron,_Neurogliaform2)|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYH1 MYH8 C4orf54 SKOR2

1.16e-04681644cfd75c373e10b3761666ccd445ba74755efeb95f
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Bcl11b|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYH1 MYH8 C4orf54 SKOR2

1.16e-04681644c25fb921dc83eecdc337353894829ae6b5192353
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Bcl11b-Inhibitory_Gad1Gad2_Id2.Bcl11b_(Interneuron,_Neurogliaform2)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYH1 MYH8 C4orf54 SKOR2

1.16e-04681644712f5f4d3a1e0c0db1a340332876206b93bdac31
Diseaseautosomal dominant hyaline body myopathy (implicated_via_orthology)

MYH1 MYH2 MYH4 MYH8

1.54e-07101564DOID:0111269 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2B3 (implicated_via_orthology)

MYH1 MYH2 MYH4 MYH8

1.54e-07101564DOID:0111602 (implicated_via_orthology)
Diseasedistal arthrogryposis type 1 (implicated_via_orthology)

MYH1 MYH2 MYH4 MYH8

1.54e-07101564DOID:0111596 (implicated_via_orthology)
Diseasedilated cardiomyopathy 1S (implicated_via_orthology)

MYH1 MYH2 MYH4 MYH8

1.54e-07101564DOID:0110454 (implicated_via_orthology)
Diseasecongenital myopathy 6 (implicated_via_orthology)

MYH1 MYH2 MYH4 MYH8

1.54e-07101564DOID:0080719 (implicated_via_orthology)
Diseaseinclusion body myositis (implicated_via_orthology)

MYH1 MYH2 MYH4 MYH8

1.54e-07101564DOID:3429 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2A (implicated_via_orthology)

MYH1 MYH2 MYH4 MYH8

1.54e-07101564DOID:0111605 (implicated_via_orthology)
Diseasefamilial hypertrophic cardiomyopathy (implicated_via_orthology)

MYH1 MYH2 MYH4 MYH8

1.54e-07101564DOID:0080326 (implicated_via_orthology)
Diseasedistal myopathy (implicated_via_orthology)

MYH1 MYH2 MYH4 MYH8

3.60e-07121564DOID:11720 (implicated_via_orthology)
Diseasemyotonia congenita (implicated_via_orthology)

MYH1 MYH2 MYH4 MYH8

3.60e-07121564DOID:2106 (implicated_via_orthology)
Diseaserestrictive cardiomyopathy (implicated_via_orthology)

MYH1 MYH2 MYH4 MYH8

5.18e-07131564DOID:397 (implicated_via_orthology)
Diseasedistal arthrogryposis (implicated_via_orthology)

MYH1 MYH2 MYH4 MYH8

9.81e-07151564DOID:0050646 (implicated_via_orthology)
Diseasecardiomyopathy (implicated_via_orthology)

MYH1 MYH2 MYH4 MYH8 SPARCL1

3.81e-05711565DOID:0050700 (implicated_via_orthology)
Diseasemyopathy (implicated_via_orthology)

MYH1 MYH2 MYH4 MYH8

1.22e-04481564DOID:423 (implicated_via_orthology)
DiseaseIntellectual Disability

SYNE1 LAMA1 GRIN2D ZBTB24 PGM3 PACS1 BRCA1 BRD4 PACS2 ZNF292

1.41e-0444715610C3714756
Diseasephenylketonuria (implicated_via_orthology)

HNF1A PAH

1.65e-0441562DOID:9281 (implicated_via_orthology)
Diseasearthrogryposis multiplex congenita (is_implicated_in)

MYH8 SYNE1

1.65e-0441562DOID:0080954 (is_implicated_in)
Diseaseanxiety, vitamin D measurement

TMCO3 SMYD3

5.73e-0471562EFO_0004631, EFO_0005230
Diseasebenign neoplasm (implicated_via_orthology)

LRRC1 DLG3

7.62e-0481562DOID:0060072 (implicated_via_orthology)
Diseasedilated cardiomyopathy (implicated_via_orthology)

MYH1 MYH2 MYH4 MYH8

8.70e-04801564DOID:12930 (implicated_via_orthology)
DiseaseAbnormality of the face

BRD4 ZNF292

9.76e-0491562C4025871
DiseaseAlzheimer disease, fasting blood glucose measurement

OR4C3 OR4S1

9.76e-0491562EFO_0004465, MONDO_0004975
DiseaseMalignant neoplasm of breast

MYH1 DSC3 SYNE1 MRPL19 GRIN2D NCOR1 AKAP9 BRCA1 OTOF SPATA21 GOLIM4 UQCC1 LRRC7 OCLN

1.74e-03107415614C0006142
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

GRIN2D NCOR1 DLG3

2.23e-03491563DOID:0060037 (implicated_via_orthology)
Diseaseresponse to cisplatin

MRPL19 ARHGAP35 SLITRK6

2.51e-03511563GO_0072718
Diseaseextrahepatic cholestasis (biomarker_via_orthology)

HNF1A GJB1

3.59e-03171562DOID:13619 (biomarker_via_orthology)
Diseasediet measurement, HOMA-B

MAGI1 FAT3

4.48e-03191562EFO_0004469, EFO_0008111

Protein segments in the cluster

PeptideGeneStartEntry
VKSVEYLRNNFRPQQ

PTPRG

296

P23470
RYPNLVLILEAKDQQ

TMEM184C

136

Q9NVA4
NIAIRIKLNQPASLY

ACSM6

416

Q6P461
VDRYIAIKKPIQANQ

HTR2B

151

P41595
KPSQELLEYNIQQKQ

AKAP9

3116

Q99996
DALYTDLPNRQLKVQ

PGM3

441

O95394
RPDTNIQVLLDLKYN

DISP3

761

Q9P2K9
TYLKNVINPIQQLRA

CCDC148

121

Q8NFR7
KPLFTLNTYNEQQII

CCDC148

531

Q8NFR7
VENLNSIELNRKYIP

ANKRD18A

951

Q8IVF6
AIYELVRNQDLPNKT

TBC1D32

801

Q96NH3
IQKRLQEDPNYSPQR

BAG6

1106

P46379
PKRQTNQLQYLLRVV

BRD4

56

O60885
INPVIYAFRNQEIQK

GPR12

296

P47775
QNDQPILEKYVRKQQ

ANKRD62

756

A6NC57
LKENNIEQIYPVNAI

BUB3

226

O43684
QTYIIQELEKQLNRA

ANGPT1

226

Q15389
TQLIIQQSLQDIYKP

ASB14

16

A6NK59
SPLILDQNYINTKNQ

CCNL1

166

Q9UK58
KNNYIQETLLRPLQA

DTWD2

236

Q8NBA8
QRVVKADIVNYNQEP

RAB28

191

P51157
VRYLKPSQAAQAIEN

RBM45

166

Q8IUH3
NAPYNKINQRILVVD

CD274

131

Q9NZQ7
ELTQDFLPYKQQLQL

OPHN1

216

O60890
PPITSDQQRQLYKRN

OCLN

421

Q16625
NQEKNESRPLTQIQY

PTPN4

801

P29074
QNYQRIRIQESPGKV

MCM2

371

P49736
RLVADQKTNLPEYLQ

LTN1

1366

O94822
VRNDNQVPKLLYLTT

RADX

446

Q6NSI4
QPPKEQQQLETVKRY

CFAP99

221

D6REC4
RIQDQKVPYIFRDNQ

CHIT1

316

Q13231
LNSRYNLNIKNPIEA

PAN2

926

Q504Q3
NPLIYSLRNEEVKNA

OR8K5

286

Q8NH50
LSLQNNQLEKIYPEE

PODN

101

Q7Z5L7
INRKTQYENPVLEAK

MAGI1

381

Q96QZ7
DQQQNEIIVKRYLTP

NEMF

546

O60524
REQQPYEGNINKVTI

LRRC7

1391

Q96NW7
EQTYRNVKSLIEPVN

MYO19

111

Q96H55
LPKNEVQLNAYVLQE

KIAA0319L

321

Q8IZA0
LQRATPEQYQILKEN

FDPS

341

P14324
NQLLPELQVIHNRYK

IPO11

476

Q9UI26
IPNLTKYQIILARDQ

FANCM

326

Q8IYD8
LKYVRGLLQTEPQNN

FIS1

91

Q9Y3D6
INQQLDTKQPRQYFI

MYH8

446

P13535
LNQQLRVEKGYPRNI

MMP19

451

Q99542
LLNPVIYTLRNQEVK

OR4N2

281

Q8NGD1
NPLIYTLRNNDVKNA

OR4S1

281

Q8NGB4
NPLIYTLRNAEVKNA

OR4S2

281

Q8NH73
NPIIYSLRNKQVIDS

OR5H2

291

Q8NGV7
INQQLDTKQPRQYFI

MYH2

446

Q9UKX2
RQKNIPFYISVLEEN

GLYATL1

256

Q969I3
VKAVQQYPENAALQI

LRRK2

296

Q5S007
QQILFQAYERQKNPS

HNF1A

211

P20823
RYTIVQQQIPSFLQK

TUBGCP2

431

Q9BSJ2
INQQLDTKQPRQYFI

MYH1

446

P12882
QALQETEPNYQVLIR

ANXA9

281

O76027
NPLIYTLRNAEVKNA

OR4C11

281

Q6IEV9
LQIPRKTVYDQLNHI

PACS2

466

Q86VP3
LKPENYENVQSLLTN

MPPED1

176

O15442
QQYLNSKINSELQVP

DRC1

716

Q96MC2
RAYAPEQLQKQDNLT

POLA1

1191

P09884
PYTQRIEVLDNTQQL

PAH

416

P00439
NQLRELPEQFFQLVK

LRRC1

46

Q9BTT6
TQIPRKVVYDQLNQI

PACS1

541

Q6VY07
PYNNNRVKLIADASV

PTPRQ

2071

Q9UMZ3
IKFQSPYEEQLEQQR

GOLIM4

401

O00461
QARLLIEKYEPNQQF

PLCB3

271

Q01970
SLQNRNYPSQEELIK

BRCA1

1516

P38398
RAVDLTKPYQNQQLS

CCSER2

246

Q9H7U1
PIVLQEREFLKNYVQ

PIKFYVE

726

Q9Y2I7
NYITNAVQQKRPTAL

PIKFYVE

1896

Q9Y2I7
DNKRPVLVLQNEALY

GRHL1

6

Q9NZI5
LPSKIRINLEDNVQY

E2F6

36

O75461
ENVIAQRKTQIYSDP

DOCK11

46

Q5JSL3
PKLQRVQDSNLEYSL

DOCK11

1091

Q5JSL3
DPNKQTVISENYLVR

DOCK2

246

Q92608
VLSVVKPLNYEENRQ

DSC3

416

Q14574
KPLNYEENRQVNLEI

DSC3

421

Q14574
VPLLLDQDYVNLKNQ

CCNL2

161

Q96S94
RDAPSVNKLVYENIN

FRS2

296

Q8WU20
VQELQPYKVLQLEQL

CCDC166

141

P0CW27
QLVYRTEVVKNNLNP

CPNE7

266

Q9UBL6
EVLNTKPDYQKILQN

DSN1

266

Q9H410
RKNYSRNNITLVQDP

FAT3

4181

Q8TDW7
LYLNSISNQPKDENI

CCDC66

186

A2RUB6
IQKIYQELAFSRPQQ

CYP11B1

271

P15538
EKIENIYNRSQPVLQ

ACSL5

556

Q9ULC5
VPDKQQVLQEAYRVL

AS3MT

161

Q9HBK9
LDPYSQEQREQLQVL

ELMO3

301

Q96BJ8
NAIKRLQQAQLYPIA

DLG3

726

Q92796
QVLVQELEQYQLLPK

BRWD1

36

Q9NSI6
PEYKQNEINKLLSEQ

GJB1

241

P08034
ALADYIRQQKSDPIQ

ERP44

131

Q9BS26
YLEQVKRQRGDPQTQ

FPGS

61

Q05932
QLSQALRKPEYEQKV

KIAA1210

1296

Q9ULL0
IENPEMLKYQRRQQQ

HIRA

396

P54198
YLKQVQQPSVAQLRS

WTAP

96

Q15007
EELIRLQNSYQPTNK

DDX46

1011

Q7L014
DLQPQKAQTILAQYL

GRK1

101

Q15835
YESVELTQQLLRQPQ

HINFP

396

Q9BQA5
NEPSNVRAKQNIIYA

C4orf54

531

D6RIA3
ERTYQELLVNQNPIA

NHP2

21

Q9NX24
SAKENRQAPVLLQTY

AUNIP

236

Q9H7T9
DSVVRKQYVQQPTDL

FAM126B

401

Q8IXS8
IRDKENYISKQLNPV

OTOF

1526

Q9HC10
LNPIIYSLRNSEVKN

OR10A5

286

Q9H207
ILIENKINPNVQDYA

INVS

441

Q9Y283
VQQIDAAVYLREPQK

MMP20

391

O60882
NPLIYTLRNEEVKNA

OR4C3

281

Q8NH37
NPLIYTLRNTEVKNA

OR4C5

296

Q8NGB2
YPNLSNQQTREFVEK

FES

761

P07332
DPVQNVVQVLEKQYL

KIF13A

596

Q9H1H9
YQIDDKPNNQIRISK

MRPS30

231

Q9NP92
QQPSQLLRRYNVAKV

SOX11

261

P35716
QLNVSPQISKYNLEL

TRMT5

161

Q32P41
QIFQQITENLVYEKP

TEX55

511

Q96M34
ITEYLRKNIAQLQPD

SLITRK6

771

Q9H5Y7
IDSQNNQYILTKPRD

TMCO3

246

Q6UWJ1
RQEPEEQSLQKLYQN

SPATA21

196

Q7Z572
YEPQLNRLKEKAQQL

SYNE1

3226

Q8NF91
VLEQEQEQVLYSRPN

SYNE1

6316

Q8NF91
EYRNQTNLPTENVDK

TCAF1

851

Q9Y4C2
NNRRTPQDIYNQLKI

NCKAP5

1586

O14513
PQDIYNQLKIEPRNR

NCKAP5

1591

O14513
SIPREVVAYNKNIND

RBL1

886

P28749
LNPLIYSLRNQEVKN

OR5AL1

301

P0C617
EDLLSQIQENYQKPL

LAMA1

1726

P25391
VVKANQAENDPTRQY

NCOR1

1996

O75376
QKYVPGLQTQNIQLD

GUCY1B2

216

O75343
EYIEALNTGKLQQQP

POLR3A

726

O14802
INQQLDTKQPRQYFI

MYH4

446

Q9Y623
LLPAVQQEQEFYEQK

RNF216

471

Q9NWF9
IIPYFEALKQQSQQI

ARHGAP35

256

Q9NRY4
DIVQELKQQNPRLVY

PDXK

96

O00764
NSERLPDINIYQLKV

SMYD3

316

Q9H7B4
REQEKLNRQYNPILS

B3GNT2

61

Q9NY97
EKIENIYIRSQPVAQ

ACSL6

571

Q9UKU0
LSVYLRANVPNKVIQ

CLTC

476

Q00610
LPDQSKQQQIYQELT

CLEC4M

241

Q9H2X3
VTQARALNQAKYIPE

NCAPD3

261

P42695
LDGSQYNPVKQQLVR

COASY

121

Q13057
LYNPRVQEIQVVKLE

MRPL19

166

P49406
YVQQLKVIDNQRELS

RAPGEF3

901

O95398
PGLQEKRKVEQLQYN

RORC

431

P51449
LKQTQPERYIHLENL

SMU1

106

Q2TAY7
EYVPQRLKNLNEINK

SESN3

146

P58005
SITKREENQEQPRNY

SPARCL1

156

Q14515
ISKREQLEQQVPENY

WASH4P

231

A8MWX3
KLQQRVEPSIQVYLE

ZNF292

301

O60281
NENVERYTQFLQKPQ

TTC41P

6

Q6P2S7
ISKREQLEQQVPENY

WASH3P

216

C4AMC7
LVDISNNLKINQYPE

STEAP4

101

Q687X5
LYPSSEIQLNNKVAR

STAM2

191

O75886
KNNAPVQILQEYVNL

VIPAS39

416

Q9H9C1
SEQIPGIDIQLNRKY

UQCC1

56

Q9NVA1
QEYANLQVSEPQIRE

POGLUT2

461

Q6UW63
QQLQIIPYAASLIRK

SKOR2

991

Q2VWA4
VREIQRLYNQGKPVN

ARHGAP8

271

P85298
GLQQLQQRQKYLIEF

ZMYND12

76

Q9H0C1
EEVRNILQLQPYQLS

ZBTB24

531

O43167
RKLAEKQEQNDQYTP

ZNF827

171

Q17R98
RPEQYIKNSFQQVIL

ZNF708

86

P17019
QLQKFAQYLISELPQ

ZSWIM8

231

A7E2V4
NILADPENIVTYKNR

ZGRF1

171

Q86YA3
LALVNNTQPKRIDLY

TTC37

1286

Q6PGP7
ATLQYTNPQLLEQLK

WDR33

546

Q9C0J8
KQYIFQLSSLNPQER

TOPBP1

1266

Q92547
SKREQLEQQVPENYF

WASH6P

201

Q9NQA3
IGDNYQTQLIPVQKA

ZP4

391

Q12836
IQKDVEYRLPFTINN

VPS37A

46

Q8NEZ2
LNKDPSYSLQVQRQV

SIGLEC16

16

A6NMB1
KYIQRQQTINLVVVP

MX2

251

P20592
INNYLLEKSRVIVQQ

MYO1D

181

O94832
YNQPRVEEALTQLKA

GRIN2D

736

O15399