Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
HumanPheno	Cerebellar ataxia associated with quadrupedal gait	VLDLR ATP8A2 ITPR1	6.60e-08	4	14	3	HP:0009878
Domain	Aquaporin_12	AQP12A AQP12B	6.20e-06	2	47	2	IPR023265
Domain	SMR-like	SMR3A SMR3B	1.86e-05	3	47	2	IPR026288
Domain	PROL5-SMR	SMR3A SMR3B	1.86e-05	3	47	2	PF15621
Domain	Aquaporin_11/12	AQP12A AQP12B	1.86e-05	3	47	2	IPR016697
Domain	Cyt_P450_E_grp-IV	CYP8B1 CYP26C1	2.75e-04	10	47	2	IPR002403
Domain	CYTOCHROME_P450	CYP2E1 CYP8B1 CYP26C1	3.97e-04	57	47	3	PS00086
Domain	-	CYP2E1 CYP8B1 CYP26C1	4.18e-04	58	47	3	1.10.630.10
Domain	p450	CYP2E1 CYP8B1 CYP26C1	4.18e-04	58	47	3	PF00067
Domain	Cyt_P450	CYP2E1 CYP8B1 CYP26C1	4.62e-04	60	47	3	IPR001128
Domain	MIP	AQP12A AQP12B	5.53e-04	14	47	2	PS00221
Domain	MIP	AQP12A AQP12B	5.53e-04	14	47	2	PF00230
Domain	P_typ_ATPase_c	ATP9A ATP8A2	5.53e-04	14	47	2	IPR032630
Domain	P-type_ATPase_N	ATP9A ATP8A2	5.53e-04	14	47	2	IPR032631
Domain	P-type_ATPase_IV	ATP9A ATP8A2	5.53e-04	14	47	2	IPR006539
Domain	PhoLip_ATPase_C	ATP9A ATP8A2	5.53e-04	14	47	2	PF16212
Domain	PhoLip_ATPase_N	ATP9A ATP8A2	5.53e-04	14	47	2	PF16209
Domain	MIP	AQP12A AQP12B	6.37e-04	15	47	2	IPR000425
Domain	-	AQP12A AQP12B	6.37e-04	15	47	2	1.20.1080.10
Domain	Aquaporin-like	AQP12A AQP12B	6.37e-04	15	47	2	IPR023271
Domain	-	ATP9A ATP8A2	2.93e-03	32	47	2	3.40.1110.10
Domain	-	ATP9A ATP8A2	2.93e-03	32	47	2	2.70.150.10
Domain	ATPase_P-typ_cyto_domN	ATP9A ATP8A2	3.50e-03	35	47	2	IPR023299
Domain	P_typ_ATPase	ATP9A ATP8A2	3.70e-03	36	47	2	IPR001757
Domain	ATPase_P-typ_P_site	ATP9A ATP8A2	3.70e-03	36	47	2	IPR018303
Domain	ATPASE_E1_E2	ATP9A ATP8A2	3.70e-03	36	47	2	PS00154
Domain	ATPase_P-typ_transduc_dom_A	ATP9A ATP8A2	3.90e-03	37	47	2	IPR008250
Domain	E1-E2_ATPase	ATP9A ATP8A2	3.90e-03	37	47	2	PF00122
Domain	-	VLDLR NHLRC2	4.33e-03	39	47	2	2.120.10.30
Domain	6-blade_b-propeller_TolB-like	VLDLR NHLRC2	5.98e-03	46	47	2	IPR011042
Domain	Cyt_P450_CS	CYP2E1 CYP26C1	7.87e-03	53	47	2	IPR017972
Domain	-	PLXNA4 CORO7 RBBP4 NBEAL2	9.69e-03	333	47	4	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	PLXNA4 CORO7 RBBP4 NBEAL2	9.89e-03	335	47	4	IPR015943
Domain	-	ATP9A ATP8A2	1.13e-02	64	47	2	3.40.50.1000
Domain	Ig_I-set	SDK2 ISLR CEACAM20	1.21e-02	190	47	3	IPR013098
Domain	I-set	SDK2 ISLR CEACAM20	1.21e-02	190	47	3	PF07679
Pubmed	Granulocyte colony-stimulating factor promotes neovascularization by releasing vascular endothelial growth factor from neutrophils.	CSF3 VEGFA	1.87e-06	2	48	2	16223785
Pubmed	Postinfarction Cardiac Remodeling Proceeds Normally in Granulocyte Colony-Stimulating Factor Knockout Mice.	CSF3 VEGFA	1.87e-06	2	48	2	25976246
Pubmed	Identification of a novel aquaporin, AQP12, expressed in pancreatic acinar cells.	AQP12A AQP12B	1.87e-06	2	48	2	15809071
Pubmed	Temporal alteration of serum G-CSF and VEGF levels in perinatal asphyxia treated with head cooling.	CSF3 VEGFA	1.87e-06	2	48	2	22944463
Pubmed	Pancreas-specific aquaporin 12 null mice showed increased susceptibility to caerulein-induced acute pancreatitis.	AQP12A AQP12B	1.87e-06	2	48	2	19726746
Pubmed	Genetic analysis of the aquaporin water channels AQP12A and AQP12B in patients with chronic pancreatitis.	AQP12A AQP12B	1.87e-06	2	48	2	36167651
Pubmed	Plexin-A4 promotes tumor progression and tumor angiogenesis by enhancement of VEGF and bFGF signaling.	PLXNA4 VEGFA	5.59e-06	3	48	2	21832283
Pubmed	Retinal lipid and glucose metabolism dictates angiogenesis through the lipid sensor Ffar1.	VLDLR VEGFA	5.59e-06	3	48	2	26974308
Pubmed	Copy number variation of age-related macular degeneration relevant genes in the Korean population.	VLDLR VEGFA	5.59e-06	3	48	2	22355348
Pubmed	Use of FMF algorithm for prediction of preeclampsia in high risk pregnancies: a single center longitudinal study.	PAPPA VEGFA	5.59e-06	3	48	2	33979553
Pubmed	The granulocyte colony-stimulating factor (G-CSF) upregulates metalloproteinase-2 and VEGF through PI3K/Akt and Erk1/2 activation in human trophoblast Swan 71 cells.	CSF3 VEGFA	5.59e-06	3	48	2	25249155
Pubmed	Characterization of P4 ATPase Phospholipid Translocases (Flippases) in Human and Rat Pancreatic Beta Cells: THEIR GENE SILENCING INHIBITS INSULIN SECRETION.	ATP9A ATP8A2	1.12e-05	4	48	2	26240149
Pubmed	Splicing variations in the ligand-binding domain of ApoER2 results in functional differences in the binding properties to Reelin.	VLDLR ITPR1	1.86e-05	5	48	2	19167437
Pubmed	Retinal microglia are critical for subretinal neovascular formation.	VLDLR VEGFA	1.86e-05	5	48	2	32437334
Pubmed	Functional candidate genes in age-related macular degeneration: significant association with VEGF, VLDLR, and LRP6.	VLDLR VEGFA	5.19e-05	8	48	2	16384981
Pubmed	Identification of cis- and trans-acting genetic variants explaining up to half the variation in circulating vascular endothelial growth factor levels.	VLDLR VEGFA	5.19e-05	8	48	2	21757650
Pubmed	The type 4 subfamily of P-type ATPases, putative aminophospholipid translocases with a role in human disease.	ATP9A ATP8A2	8.33e-05	10	48	2	15919184
Pubmed	Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants.	CYP2E1 CYP8B1 CYP26C1	1.27e-04	70	48	3	15128046
Pubmed	Differential expression of putative transbilayer amphipath transporters.	ATP9A ATP8A2	1.44e-04	13	48	2	11015572
Pubmed	Restored expression of major histocompatibility class I molecules by gene transfer of a putative peptide transporter.	VLDLR PAPPA	1.68e-04	14	48	2	2034277
Pubmed	Polymorphisms in C2, CFB and C3 are associated with progression to advanced age related macular degeneration associated with visual loss.	VLDLR VEGFA	1.68e-04	14	48	2	19015224
Pubmed	Aquaporins 8 and 9 as Possible Markers for Adult Murine Lacrimal Gland Cells.	AQP12A AQP12B	1.94e-04	15	48	2	34540996
Pubmed	Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex.	RBBP4 PCNT	1.94e-04	15	48	2	9804427
Pubmed	Discovery and refinement of loci associated with lipid levels.	VLDLR SETD2 SNX13 VEGFA	2.08e-04	211	48	4	24097068
Pubmed	Identification of RanBP 9/10 as interacting partners for protein kinase C (PKC) gamma/delta and the D1 dopamine receptor: regulation of PKC-mediated receptor phosphorylation.	DYNC1H1 ITPR1	2.50e-04	17	48	2	20395553
Pubmed	Polyhydramnios in Lrp4 knockout mice with bilateral kidney agenesis: Defects in the pathways of amniotic fluid clearance.	AQP12A AQP12B	2.50e-04	17	48	2	26847765
Pubmed	Expression patterns of the aquaporin gene family during renal development: influence of genetic variability.	AQP12A AQP12B	3.14e-04	19	48	2	19367412
Pubmed	Control of TurboID-dependent biotinylation intensity in proximity ligation screens.	ATP8A2 NBEAL2 ITPR1	3.63e-04	100	48	3	36966971
Pubmed	Report of the sixth international workshop on human chromosome 3 mapping 1995.	SLC6A6 ITPR1	3.85e-04	21	48	2	8641130
Pubmed	Distinct dynein complexes defined by DYNLRB1 and DYNLRB2 regulate mitotic and male meiotic spindle bipolarity.	DYNC1H1 PCNT	4.63e-04	23	48	2	36973253
Pubmed	PLAA Mutations Cause a Lethal Infantile Epileptic Encephalopathy by Disrupting Ubiquitin-Mediated Endolysosomal Degradation of Synaptic Proteins.	VLDLR ITPR1	5.05e-04	24	48	2	28413018
Pubmed	PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.	PLXNA4 SDK2 ISLR	5.75e-04	117	48	3	17145500
Pubmed	DNA polymerase POLD1 promotes proliferation and metastasis of bladder cancer by stabilizing MYC.	RBBP4 PCNT ITPR1	5.89e-04	118	48	3	37105989
Pubmed	The c-Ski family member and transcriptional regulator Corl2/Skor2 promotes early differentiation of cerebellar Purkinje cells.	VLDLR ITPR1	6.89e-04	28	48	2	24491816
Pubmed	Differential gene expression profiling of the molar tooth germ in peroxisome proliferator-activated receptor-alpha (PPAR-alpha) knockout mouse and in wild-type mouse: molar tooth phenotype of PPAR-alpha knockout mouse.	VLDLR VEGFA	9.01e-04	32	48	2	19320717
Pubmed	Polymorphisms in the estrogen receptor 1 and vitamin C and matrix metalloproteinase gene families are associated with susceptibility to lymphoma.	FCER2 CYP2E1 VEGFA	9.87e-04	141	48	3	18636124
Pubmed	CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice.	DYNC1H1 PTH2R VEGFA	1.09e-03	146	48	3	29688375
Pubmed	Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.	RBBP4 DYNC1H1 PCNT ITPR1	1.24e-03	340	48	4	29478914
Cytoband	4q13.3	SMR3A SMR3B	8.97e-04	42	48	2	4q13.3
GeneFamily	Aquaporins	AQP12A AQP12B	3.46e-04	14	36	2	305
GeneFamily	ATPase phospholipid transporting	ATP9A ATP8A2	3.98e-04	15	36	2	1210
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	SDK2 ISLR CEACAM20	3.99e-03	161	36	3	593
GeneFamily	WD repeat domain containing	CORO7 RBBP4 NBEAL2	1.51e-02	262	36	3	362
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PLXNA4 PAPPA SDK2 CSF3 VEGFA	2.36e-06	199	48	5	8b86c69aaf60feff53aa782559cfece7342a23de
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_ALM_Olfr111_Nxph1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SDK2 NBEAL2 PTH2R GADL1	9.13e-06	122	48	4	dba1c647172a11381efcb178a23808161908daa3
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3\|GI_small-bowel / Manually curated celltypes from each tissue	PDE1C SDK2 CYP26C1 VEGFA	3.06e-05	166	48	4	773673a5d0430640439845b264740bfbbdad0cb2
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like\|GI_small-bowel / Manually curated celltypes from each tissue	PDE1C SDK2 CYP26C1 VEGFA	3.14e-05	167	48	4	3ae46c6363da76c8e1f5579e6027bf88ed637a44
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PAPPA B3GNT9 SDK2 ATP8A2	4.11e-05	179	48	4	a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l1\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VLDLR B3GNT9 ISLR GADL1	4.58e-05	184	48	4	e33e2a887aafba7b6a31f00bb0dbe974b4359fd6
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PLXNA4 PAPPA SDK2 VEGFA	5.18e-05	190	48	4	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-fibroblast\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VLDLR B3GNT9 ISLR GADL1	5.29e-05	191	48	4	9214655dca96d766737c9f30b624d7fe7050342e
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PLXNA4 PAPPA SDK2 VEGFA	5.40e-05	192	48	4	ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCell	proximal-Epithelial-Serous\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SMR3A SPDEF PTH2R SMR3B	5.73e-05	195	48	4	cb62f04f0e45bfb36eed2e7a3fc54d6d390b2ed1
ToppCell	proximal-Epithelial-Serous-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SMR3A SPDEF PTH2R SMR3B	5.73e-05	195	48	4	06b73abc1f32543f2a51db52dc6424a2a398fe0f
ToppCell	proximal-3-Epithelial-Serous\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SMR3A SPDEF PTH2R SMR3B	5.73e-05	195	48	4	24a6a566143b04e37ad002e4c55037a0460ac2ef
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VLDLR B3GNT9 ISLR VEGFA	5.85e-05	196	48	4	2029f58ce6a7b8c35d3a7496c3341391990909ce
ToppCell	proximal-Epithelial-Ionocyte\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PDE1C SDK2 CORO7 CYP26C1	5.97e-05	197	48	4	e5d5accefaacea5ed2e22f906f5bcbc75083f287
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PAPPA SDK2 ISLR VEGFA	5.97e-05	197	48	4	fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell	proximal-Epithelial-Ionocyte-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PDE1C SDK2 CORO7 CYP26C1	5.97e-05	197	48	4	f65c35761da7c168d5c6e4d7edf5dafa26652fe4
ToppCell	proximal-3-Epithelial-Ionocyte\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PDE1C SDK2 CORO7 CYP26C1	5.97e-05	197	48	4	288492fc67d8e81349d38e82caf1f1890276b299
ToppCell	Bronchial-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Serous\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SMR3A SPDEF PTH2R SMR3B	5.97e-05	197	48	4	92a66e3b5ddc3d55527c31e0d9cff15c2203ecfc
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PLXNA4 SDK2 ISLR VEGFA	6.20e-05	199	48	4	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	PLXNA4 SDK2 ISLR VEGFA	6.33e-05	200	48	4	a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
Disease	neutrophil count	SPPL3 VLDLR RIOK3 SETD2 NHLRC2 CSF3 FCER2 CYP8B1 NBEAL2 SNX13 PCNT VEGFA	7.25e-07	1382	45	12	EFO_0004833
Disease	Cerebellar Ataxia, Mental Retardation, And Dysequilibrium Syndrome 1	VLDLR ATP8A2	2.27e-06	2	45	2	C4551552
Disease	acoustic neuroma (is_implicated_in)	CYP2E1 VEGFA	6.82e-06	3	45	2	DOID:12689 (is_implicated_in)
Disease	myeloid white cell count	SPPL3 VLDLR RIOK3 SETD2 NHLRC2 CSF3 CYP8B1 SNX13 VEGFA	1.00e-05	937	45	9	EFO_0007988
Disease	cerebellar ataxia, mental retardation and dysequlibrium syndrome (is_implicated_in)	VLDLR ATP8A2	1.36e-05	4	45	2	DOID:0050997 (is_implicated_in)
Disease	Dysequilibrium syndrome	VLDLR ATP8A2	2.27e-05	5	45	2	C0394006
Disease	very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	SPDEF NHLRC2 CEACAM20 SNX13 VEGFA	5.03e-05	264	45	5	EFO_0008317, EFO_0020944
Disease	Malignant neoplasm of liver	CSF3 CYP2E1 TMEM132D GADL1	6.57e-05	142	45	4	C0345904
Disease	Liver neoplasms	CSF3 CYP2E1 TMEM132D GADL1	6.57e-05	142	45	4	C0023903
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	SPDEF NHLRC2 CEACAM20 SNX13 VEGFA	7.97e-05	291	45	5	EFO_0008317, EFO_0020946
Disease	vascular endothelial growth factor A, isoform 121 measurement	VLDLR VEGFA	8.13e-05	9	45	2	EFO_0020847
Disease	vascular endothelial growth factor A measurement	VLDLR VEGFA	1.49e-04	12	45	2	EFO_0010804
Disease	extrinsic allergic alveolitis (is_marker_for)	CYP2E1 VEGFA	2.05e-04	14	45	2	DOID:841 (is_marker_for)
Disease	obesity (implicated_via_orthology)	ADAMTS20 SDK2 CORO7 ITPR1	3.23e-04	215	45	4	DOID:9970 (implicated_via_orthology)
Disease	Hemangiosarcoma	CSF3 VEGFA	3.43e-04	18	45	2	C0018923
Disease	Drug-Induced Liver Disease	CSF3 CYP2E1 CYP8B1 ITPR1 VEGFA	3.66e-04	404	45	5	C0860207
Disease	Drug-Induced Acute Liver Injury	CSF3 CYP2E1 CYP8B1 ITPR1 VEGFA	3.66e-04	404	45	5	C3658290
Disease	Chemical and Drug Induced Liver Injury	CSF3 CYP2E1 CYP8B1 ITPR1 VEGFA	3.66e-04	404	45	5	C4277682
Disease	Hepatitis, Drug-Induced	CSF3 CYP2E1 CYP8B1 ITPR1 VEGFA	3.66e-04	404	45	5	C1262760
Disease	Hepatitis, Toxic	CSF3 CYP2E1 CYP8B1 ITPR1 VEGFA	3.66e-04	404	45	5	C0019193
Disease	Chemically-Induced Liver Toxicity	CSF3 CYP2E1 CYP8B1 ITPR1 VEGFA	3.66e-04	404	45	5	C4279912
Disease	triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement	SPDEF NHLRC2 CEACAM20 VEGFA	3.84e-04	225	45	4	EFO_0008317, EFO_0020947
Disease	middle cerebral artery infarction (biomarker_via_orthology)	CSF3 CYP2E1 VEGFA	3.91e-04	93	45	3	DOID:3525 (biomarker_via_orthology)
Disease	ethylmalonate measurement	SPPL3 TMEM132D	4.25e-04	20	45	2	EFO_0020009
Disease	Low Grade Lymphoma (neoplasm)	CSF3 CYP2E1	4.69e-04	21	45	2	C0079747
Disease	Lymphoma, Intermediate-Grade	CSF3 CYP2E1	4.69e-04	21	45	2	C0079741
Disease	High Grade Lymphoma (neoplasm)	CSF3 CYP2E1	4.69e-04	21	45	2	C0079740
Disease	Diffuse Mixed-Cell Lymphoma	CSF3 CYP2E1	4.69e-04	21	45	2	C0079757
Disease	Lymphoma, Undifferentiated	CSF3 CYP2E1	4.69e-04	21	45	2	C0024306
Disease	Reticulosarcoma	CSF3 CYP2E1	4.69e-04	21	45	2	C0024302
Disease	Lymphoma, Mixed-Cell	CSF3 CYP2E1	4.69e-04	21	45	2	C0024304
Disease	Lymphoma, Diffuse	CSF3 CYP2E1	4.69e-04	21	45	2	C3714542
Disease	very low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	SPDEF NHLRC2 CEACAM20 VEGFA	4.82e-04	239	45	4	EFO_0008317, EFO_0020945
Disease	Lymphoma, Non-Hodgkin, Familial	CSF3 CYP2E1	5.15e-04	22	45	2	C4721532
Disease	Lymphoma, Small Noncleaved-Cell	CSF3 CYP2E1	5.15e-04	22	45	2	C0079770
Disease	Head Neoplasms	CSF3 VEGFA	6.14e-04	24	45	2	C0018675
Disease	Upper Aerodigestive Tract Neoplasms	CSF3 VEGFA	6.14e-04	24	45	2	C0887900
Disease	Cancer of Head	CSF3 VEGFA	6.14e-04	24	45	2	C0751177
Disease	Neck Neoplasms	CSF3 VEGFA	6.67e-04	25	45	2	C0027533
Disease	Cancer of Neck	CSF3 VEGFA	6.67e-04	25	45	2	C0746787
Disease	cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement	NHLRC2 CEACAM20 SNX13 VEGFA	8.25e-04	276	45	4	EFO_0004612, EFO_0020943
Disease	cholesterol:total lipids ratio, intermediate density lipoprotein measurement	CEACAM20 SNX13 VEGFA	8.42e-04	121	45	3	EFO_0008595, EFO_0020943
Disease	triglycerides:total lipids ratio, intermediate density lipoprotein measurement	CEACAM20 SNX13 VEGFA	9.68e-04	127	45	3	EFO_0008595, EFO_0020947
Disease	Lymphoma, Non-Hodgkin	CSF3 CYP2E1	1.10e-03	32	45	2	C0024305
Disease	eating disorder	ATP8A2 GADL1	1.10e-03	32	45	2	EFO_0005203
Disease	Head and Neck Neoplasms	CSF3 VEGFA	1.17e-03	33	45	2	C0018671
Disease	type 2 diabetes mellitus (is_marker_for)	PAPPA CYP2E1 VEGFA	1.18e-03	136	45	3	DOID:9352 (is_marker_for)
Disease	phospholipids:total lipids ratio, high density lipoprotein cholesterol measurement	NHLRC2 CEACAM20 SNX13 VEGFA	1.22e-03	307	45	4	EFO_0004612, EFO_0020946
Disease	sexual dimorphism measurement	USP49 SPDEF RIOK3 PAPPA ISLR SNX13 VEGFA	1.33e-03	1106	45	7	EFO_0021796

Protein segments in the cluster

Peptide	Gene	Start	Entry
LCLHSMSLWGSWGSR	nan	276	Q6ZR03
WAWELSDLHLLQSLM	AQP12A	121	Q8IXF9
QLHLLSSFLWLEMVW	HTR3E	81	A5X5Y0
SWGHHWMGILLSASL	CEACAM20	6	Q6UY09
MHLALTTVLLWAWGL	FAM187A	1	A6NFU0
WAWELSDLHLLQSLM	AQP12B	121	A6NM10
FSHLAVWGSMLTWLV	ATP8A2	1026	Q9NTI2
MWVAKWLTGLLYHLS	ADAMTS20	1	P59510
FLLLVSMWRQVHSSW	CYP2E1	16	P05181
GTLEPHWSGLLWTAM	ITPR1	2311	Q14643
HWSGLLWTAMLISLA	ITPR1	2316	Q14643
SRLAWMGTWEHLVST	CORO7	216	P57737
MQELHLLWWALLLGL	ISLR	1	O14498
WNWTCLLSHLLMVGM	PLXNA4	6	Q9HCM2
MVILLHLRTWSSEGW	OR4X2	211	Q8NGF9
AKAWDLHHRWTMSLL	PDE1C	381	Q14123
AGLLTLLLLWHWDTT	FCER2	36	P06734
LLMVALTIQTWHWLM	ATP9A	966	O75110
WHWLMTVAELLSLAC	ATP9A	976	O75110
MRLWSWVLHLGLLSA	PAPPA	1	Q13219
SLWPMASAHLLESSW	PCNT	2096	O95613
LWIAMAGTHQIWALL	NHLRC2	356	Q8NBF2
MTHALEWPSLTAQWL	RBBP4	36	Q09028
MSSAAADHWAWLLVL	GET1	1	O00258
LSLAQHLWTLRWMLS	CYP26C1	26	Q6V0L0
MSLGIHRVWKDLLLW	COQ5	86	Q5HYK3
KLMALQLLLWHSALW	CSF3	11	P09919
WMRTLHTTASNWLHL	DYNC1H1	4376	Q14204
LWLHVDASWGGSALM	GADL1	296	Q6ZQY3
TLHGSNMKWSAAVLW	MT-CO1	326	P00395
MWGLLIWTLLALHQI	SDK2	1	Q58EX2
MLTSKGWSLDASCWH	CYP8B1	151	Q9UNU6
IMLWHMTNHLTTWLA	TAS2R42	86	Q7RTR8
MLTEASLSIWGWGSL	SNX13	1	Q9Y5W8
WAIGLGWSLALSSML	SLC6A6	541	P31641
MGTLWHHWSPVLISL	TMEM132D	6	Q14C87
LWAHGTVLRNLTEMW	TMEM170B	21	Q5T4T1
HSMALLHWGALWRQL	NBEAL2	1796	Q6ZNJ1
MKSLTWILGLWALAA	SMR3B	1	P02814
GLSAADIWLMWRLLH	B3GNT9	366	Q6UX72
NMLWHAGKVWLIDVS	RIOK3	411	O14730
LSISLHVWVMNLRWK	TMEM138	91	Q9NPI0
VLHAHLDIWKSAAWM	SPDEF	201	O95238
IWVLTGHWLLMDALA	SPPL3	156	Q8TCT6
SLGHTDWARLWVQLM	SPIRE2	236	Q8WWL2
MKSLTWILGLWALAA	SMR3A	1	Q99954
LHTLFRVMWSGKWAL	USP49	361	Q70CQ1
ASLHVWGWLMLGSCL	PTH2R	6	P49190
LERHGLSLLWIWMAE	SETD2	1771	Q9BYW2
WLLAGASMSSLNKWI	SLC35E4	56	Q6ICL7
MNFLLSWVHWSLALL	VEGFA	1	P15692
MGTSALWALWLLLAL	VLDLR	1	P98155