Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionphosphatidylserine transfer activity

OSBPL5 OSBPL8

1.67e-052822GO:0140343
GeneOntologyMolecularFunctionlow voltage-gated calcium channel activity

CACNA1I CACNA1G

4.98e-053822GO:0008332
GeneOntologyMolecularFunctionhistone H3K4me/H3K4me2/H3K4me3 demethylase activity

KDM5A KDM5D

2.47e-046822GO:0034647
GeneOntologyMolecularFunctionhistone H3K4 demethylase activity

KDM5A KDM5D

4.59e-048822GO:0032453
DomainTPR-contain_dom

TMTC1 FICD P3H1 TTC21B ZFC3H1 CABIN1

5.14e-05150826IPR013026
DomainHist_deacetylase_Gln_rich_N

HDAC9 HDAC5

5.70e-053822IPR024643
DomainHDAC4_Gln

HDAC9 HDAC5

5.70e-053822PF12203
DomainVDCC_T_a1

CACNA1I CACNA1G

5.70e-053822IPR005445
DomainTPR-like_helical_dom

TMTC1 FICD P3H1 TTC21B ZFC3H1 CABIN1 P3H4

7.38e-05233827IPR011990
DomainTPR_REGION

TMTC1 FICD P3H1 TTC21B ZFC3H1 CABIN1

8.73e-05165826PS50293
DomainTPR

TMTC1 FICD P3H1 TTC21B ZFC3H1 CABIN1

8.73e-05165826PS50005
DomainLys_sp_deMease-like_dom

KDM5A KDM5D

1.14e-044822IPR013637
DomainPLU-1

KDM5A KDM5D

1.14e-044822PF08429
DomainHistone_deAcase_II_euk

HDAC9 HDAC5

1.14e-044822IPR017320
Domainzf-C5HC2

KDM5A KDM5D

1.89e-045822PF02928
DomainZnf_C5HC2

KDM5A KDM5D

1.89e-045822IPR004198
Domain-

TMTC1 FICD P3H1 TTC21B CABIN1 P3H4

3.00e-042078261.25.40.10
DomainJmjN

KDM5A KDM5D

8.38e-0410822SM00545
DomainJMJN

KDM5A KDM5D

8.38e-0410822PS51183
DomainJmjN

KDM5A KDM5D

8.38e-0410822PF02375
DomainVDCCAlpha1

CACNA1I CACNA1G

8.38e-0410822IPR002077
DomainHAT

TMTC1 ZFC3H1

8.38e-0410822IPR003107
DomainJmjN

KDM5A KDM5D

8.38e-0410822IPR003349
DomainHAT

TMTC1 ZFC3H1

8.38e-0410822SM00386
DomainHist_deacetyl

HDAC9 HDAC5

1.02e-0311822PF00850
DomainHis_deacetylse_dom

HDAC9 HDAC5

1.02e-0311822IPR023801
Domain-

HDAC9 HDAC5

1.02e-03118223.40.800.20
DomainHis_deacetylse

HDAC9 HDAC5

1.02e-0311822IPR000286
DomainOxysterol-bd

OSBPL5 OSBPL8

1.22e-0312822IPR000648
DomainOxysterol-bd_CS

OSBPL5 OSBPL8

1.22e-0312822IPR018494
DomainOxysterol_BP

OSBPL5 OSBPL8

1.22e-0312822PF01237
DomainOSBP

OSBPL5 OSBPL8

1.22e-0312822PS01013
Domain-

PLEKHH1 MTMR7 EPB41L4B ITSN1 OSBPL5 OSBPL8 ARAP1

1.65e-033918272.30.29.30
Domain-

KDM5A KDM5D

1.93e-03158221.10.150.60
DomainBRIGHT

KDM5A KDM5D

1.93e-0315822SM00501
DomainARID_dom

KDM5A KDM5D

1.93e-0315822IPR001606
DomainARID

KDM5A KDM5D

1.93e-0315822PS51011
DomainARID

KDM5A KDM5D

1.93e-0315822PF01388
DomainPH_dom-like

PLEKHH1 MTMR7 EPB41L4B ITSN1 OSBPL5 OSBPL8 ARAP1

2.67e-03426827IPR011993
DomainTPR_repeat

TMTC1 FICD TTC21B CABIN1

2.80e-03133824IPR019734
DomainPH

PLEKHH1 ITSN1 OSBPL5 OSBPL8 ARAP1

3.37e-03229825PF00169
DomainJmjC

KDM5A KDM5D

4.94e-0324822PF02373
DomainPH

PLEKHH1 ITSN1 OSBPL5 OSBPL8 ARAP1

7.58e-03278825SM00233
DomainPH_DOMAIN

PLEKHH1 ITSN1 OSBPL5 OSBPL8 ARAP1

7.69e-03279825PS50003
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

ZNF462 HDAC5 OSBPL8 CACNA1G UNC80 ARAP1 DOP1B

1.28e-0622584712168954
Pubmed

Toll-Like Receptor 2-Tpl2-Dependent ERK Signaling Drives Inverse Interleukin 12 Regulation in Dendritic Cells and Macrophages.

MAP3K8 TLR2

5.76e-06284233077627
Pubmed

INTRACELLULAR TRANSPORT. PI4P/phosphatidylserine countertransport at ORP5- and ORP8-mediated ER-plasma membrane contacts.

OSBPL5 OSBPL8

5.76e-06284226206935
Pubmed

FBXW10 promotes hepatocarcinogenesis in male patients and mice.

FBXW10B FBXW10

5.76e-06284231400758
Pubmed

Contribution of postsynaptic T-type calcium channels to parallel fibre-Purkinje cell synaptic responses.

CACNA1I CACNA1G

5.76e-06284226627919
Pubmed

Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice.

FBXW10B FBXW10

5.76e-06284237450367
Pubmed

Oxysterol-binding protein related-proteins (ORPs) 5 and 8 regulate calcium signaling at specific cell compartments.

OSBPL5 OSBPL8

5.76e-06284229748134
Pubmed

ORP5/ORP8 localize to endoplasmic reticulum-mitochondria contacts and are involved in mitochondrial function.

OSBPL5 OSBPL8

5.76e-06284227113756
Pubmed

ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P 2) and regulate its level at the plasma membrane.

OSBPL5 OSBPL8

5.76e-06284228970484
Pubmed

Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli.

HDAC9 HDAC5

5.76e-06284217988634
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PLEKHH1 ZNF462 AGO2 EPB41L4B VPS45 TUSC3 OSBPL5 TTC21B PPHLN1 CPD CHD1L CSMD1 LRRC8D ARAP1

1.25e-051489841428611215
Pubmed

PI(4,5)P2 controls plasma membrane PI4P and PS levels via ORP5/8 recruitment to ER-PM contact sites.

OSBPL5 OSBPL8

1.73e-05384229472386
Pubmed

Ethanol inhibition of a T-type Ca²+ channel through activity of protein kinase C.

CACNA1I CACNA1G

1.73e-05384223488970
Pubmed

T-type channels: release a brake, engage a gear.

CACNA1I CACNA1G

1.73e-05384226488564
Pubmed

Differential interactions of Na+ channel toxins with T-type Ca2+ channels.

CACNA1I CACNA1G

1.73e-05384218591418
Pubmed

Identification of the t-type calcium channel (Ca(v)3.1d) in developing mouse heart.

CACNA1I CACNA1G

1.73e-05384211230107
Pubmed

Prognostic relevance of a T-type calcium channels gene signature in solid tumours: A correlation ready for clinical validation.

CACNA1I CACNA1G

1.73e-05384228846697
Pubmed

Homeostatic plasticity and burst activity are mediated by hyperpolarization-activated cation currents and T-type calcium channels in neuronal cultures.

CACNA1I CACNA1G

1.73e-05384233547341
Pubmed

Calmodulin regulates Cav3 T-type channels at their gating brake.

CACNA1I CACNA1G

1.73e-05384228972185
Pubmed

Global genetic deletion of CaV3.3 channels facilitates anaesthetic induction and enhances isoflurane-sparing effects of T-type calcium channel blockers.

CACNA1I CACNA1G

1.73e-05384233299036
Pubmed

Specific contribution of human T-type calcium channel isotypes (alpha(1G), alpha(1H) and alpha(1I)) to neuronal excitability.

CACNA1I CACNA1G

1.73e-05384211927664
Pubmed

Effects of TLR-2/NF-κB signaling pathway on the occurrence of degenerative knee osteoarthritis: an in vivo and in vitro study.

TLR2 MMP13

1.73e-05384228418842
Pubmed

Dephosphorylation at a conserved SP motif governs cAMP sensitivity and nuclear localization of class IIa histone deacetylases.

HDAC9 HDAC5

1.73e-05384223297420
Pubmed

Growth differentiation factor-15 promotes glutamate release in medial prefrontal cortex of mice through upregulation of T-type calcium channels.

CACNA1I CACNA1G

1.73e-05384227353765
Pubmed

Alpha(1H) mRNA in single skeletal muscle fibres accounts for T-type calcium current transient expression during fetal development in mice.

CACNA1I CACNA1G

1.73e-05384211897840
Pubmed

Toll-like receptor 2-dependent extracellular signal-regulated kinase signaling in Mycobacterium tuberculosis-infected macrophages drives anti-inflammatory responses and inhibits Th1 polarization of responding T cells.

MAP3K8 TLR2

1.73e-05384225776754
Pubmed

FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.

TMEM230 ABCC1 MBOAT7 ALG9 OSBPL8 CPD PIGU LRRC8D

1.81e-0546884831056421
Pubmed

Defining the membrane proteome of NK cells.

ABCC1 AGO2 MBOAT7 P3H1 ALG9 OSBPL5 PEX16 OSBPL8 CPD PIGU LRRC8D CYFIP2

2.37e-051168841219946888
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ZNF462 HDAC9 KCTD12 TTC21B OSBPL8 RICTOR ZFC3H1 UNC80

2.62e-0549384815368895
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

MBOAT7 VPS45 DIAPH2 OSBPL8 CPD EIF3C PIGU DOP1B

3.06e-0550484834432599
Pubmed

LMK235, a small molecule inhibitor of HDAC4/5, protects dopaminergic neurons against neurotoxin- and α-synuclein-induced degeneration in cellular models of Parkinson's disease.

HDAC9 HDAC5

3.45e-05484234119632
Pubmed

Novel JARID1C/SMCX mutations in patients with X-linked mental retardation.

KDM5A KDM5D

3.45e-05484216541399
Pubmed

Small RNAs Recruit Chromatin-Modifying Enzymes MMSET and Tip60 to Reconfigure Damaged DNA upon Double-Strand Break and Facilitate Repair.

AGO2 KAT5

3.45e-05484226822153
Pubmed

Pharmacogenetics of antiepileptic drug efficacy in childhood absence epilepsy.

CACNA1I CACNA1G

3.45e-05484228165634
Pubmed

Identification of a transcriptional repressor related to the noncatalytic domain of histone deacetylases 4 and 5.

HDAC9 HDAC5

3.45e-05484210655483
Pubmed

Class IIa histone deacetylases: conducting development and differentiation.

HDAC9 HDAC5

3.45e-05484219412888
Pubmed

mHDA1/HDAC5 histone deacetylase interacts with and represses MEF2A transcriptional activity.

HDAC9 HDAC5

3.45e-05484210748098
Pubmed

FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression.

HDAC9 KAT5

3.45e-05484217360565
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

KAT5 HDAC5 KDM5A MAP3K8 CHD1L FOXH1 ADNP CABIN1 P3H4 CYFIP2

4.17e-05857841025609649
Pubmed

Mirk/dyrk1B decreases the nuclear accumulation of class II histone deacetylases during skeletal muscle differentiation.

HDAC9 HDAC5

5.74e-05584215546868
Pubmed

Functional interaction between class II histone deacetylases and ICP0 of herpes simplex virus type 1.

HDAC9 HDAC5

5.74e-05584215194749
Pubmed

FBXW10-S6K1 promotes ANXA2 polyubiquitination and KRAS activation to drive hepatocellular carcinoma development in males.

FBXW10B FBXW10

5.74e-05584237277019
Pubmed

Protein kinase C-related kinase targets nuclear localization signals in a subset of class IIa histone deacetylases.

HDAC9 HDAC5

5.74e-05584220188095
Pubmed

Myocyte enhancer factor 2 and class II histone deacetylases control a gender-specific pathway of cardioprotection mediated by the estrogen receptor.

HDAC9 HDAC5

5.74e-05584219893013
Pubmed

Histone deacetylase 5 acquires calcium/calmodulin-dependent kinase II responsiveness by oligomerization with histone deacetylase 4.

HDAC9 HDAC5

5.74e-05584218332106
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

PLEKHH1 HDAC9 KDM5A CORO2A VPS45 ENPP2 ITSN1 OSBPL8 EIF3C ZFC3H1 CABIN1 DOP1B

5.96e-051285841235914814
Pubmed

Calcium regulates transcriptional repression of myocyte enhancer factor 2 by histone deacetylase 4.

HDAC9 CABIN1

8.59e-05684210825153
Pubmed

Control of MEF2 transcriptional activity by coordinated phosphorylation and sumoylation.

HDAC9 HDAC5

8.59e-05684216356933
Pubmed

HDAC5 is a repressor of angiogenesis and determines the angiogenic gene expression pattern of endothelial cells.

HDAC9 HDAC5

8.59e-05684219351956
Pubmed

Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

HDAC9 ADNP ADGRL3 ARAP1

1.08e-041018449872452
Pubmed

Genome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases.

FICD CACNA1I CSMD1

1.17e-043984324709693
Pubmed

Association of COOH-terminal-binding protein (CtBP) and MEF2-interacting transcription repressor (MITR) contributes to transcriptional repression of the MEF2 transcription factor.

HDAC9 HDAC5

1.20e-04784211022042
Pubmed

A novel view of the transcriptome revealed from gene trapping in mouse embryonic stem cells.

ABCC1 ITSN1 TUSC3

1.26e-044084317540781
Pubmed

Histone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibers.

HDAC9 HDAC5

1.60e-04884217786239
Pubmed

Association of class II histone deacetylases with heterochromatin protein 1: potential role for histone methylation in control of muscle differentiation.

HDAC9 HDAC5

1.60e-04884212242305
Pubmed

Evolutionary insights into T-type Ca2+ channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue.

CACNA1I CACNA1G

1.60e-04884228330839
Pubmed

The mammalian oxysterol-binding protein-related proteins (ORPs) bind 25-hydroxycholesterol in an evolutionarily conserved pocket.

OSBPL5 OSBPL8

1.60e-04884217428193
Pubmed

Neuroepithelial progenitors generate and propagate non-neuronal action potentials across the spinal cord.

CACNA1I CACNA1G

1.60e-04884234478646
Pubmed

Intracellular calcium plays an essential role in cardiac development.

CACNA1I CACNA1G

1.60e-04884212761855
Pubmed

Congenital Disorders of N-Linked Glycosylation and Multiple Pathway Overview

ALG9 TUSC3 GMPPA

1.68e-044484320301507
Pubmed

Impaired Spermatogenesis, Muscle, and Erythrocyte Function in U12 Intron Splicing-Defective Zrsr1 Mutant Mice.

TUSC3 DIAPH2 TMEM80

2.04e-044784329617656
Pubmed

Periphilin is strongly expressed in the murine nervous system and is indispensable for murine development.

MTMR7 PPHLN1

2.05e-04984219621438
Pubmed

Human HDAC7 histone deacetylase activity is associated with HDAC3 in vivo.

HDAC9 HDAC5

2.05e-04984211466315
Pubmed

ARAP1 association with CIN85 affects epidermal growth factor receptor endocytic trafficking.

KCTD12 ARAP1

2.05e-04984221275903
Pubmed

Histone deacetylases 5 and 9 govern responsiveness of the heart to a subset of stress signals and play redundant roles in heart development.

HDAC9 HDAC5

2.05e-04984215367668
Pubmed

Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein.

KAT5 HDAC5

2.05e-04984212150997
Pubmed

International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.

CACNA1I CACNA1G

2.05e-04984216382099
Pubmed

ORP/Osh mediate cross-talk between ER-plasma membrane contact site components and plasma membrane SNAREs.

OSBPL5 OSBPL8

2.05e-04984232734583
Pubmed

The DnaJ-related factor Mrj interacts with nuclear factor of activated T cells c3 and mediates transcriptional repression through class II histone deacetylase recruitment.

HDAC9 HDAC5

2.05e-04984216260608
Pubmed

Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph.

TMEM230 HDAC5 TLR2 MMP13 PIGU

2.49e-0423184521048031
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

EPB41L4B SMCHD1 LAMA5 CACNA1G DYSF CABIN1

2.54e-0436384614691545
Pubmed

Class II histone deacetylases: versatile regulators.

HDAC9 HDAC5

2.56e-041084212711221
Pubmed

Isolation of novel mouse genes that were differentially expressed in W/W(V) mouse fundus.

KAT5 MBOAT7

2.56e-041084215065000
Pubmed

Cav3.2 T-type calcium channel is required for the NFAT-dependent Sox9 expression in tracheal cartilage.

CACNA1I CACNA1G

2.56e-041084224778262
Pubmed

Histone Deacetylase 1 Is Essential for Rod Photoreceptor Differentiation by Regulating Acetylation at Histone H3 Lysine 9 and Histone H4 Lysine 12 in the Mouse Retina.

HDAC9 HDAC5

2.56e-041084228028172
Pubmed

Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.

KCTD12 ABCC1 FICD AGO2 TUSC3 TLR2

2.86e-0437184615747579
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

AGO2 SMCHD1 OSBPL5 LAMA5 CACNA1G ADNP ARAP1

2.99e-0452984714621295
Pubmed

MAPT/Tau accumulation represses autophagy flux by disrupting IST1-regulated ESCRT-III complex formation: a vicious cycle in Alzheimer neurodegeneration.

HDAC9 HDAC5

3.13e-041184231223056
Pubmed

The OSBP-related protein family in humans.

OSBPL5 OSBPL8

3.13e-041184211483621
Pubmed

Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects.

HDAC9 PPHLN1 CSMD1 DYSF

3.20e-0413484424324551
Pubmed

New nomenclature for chromatin-modifying enzymes.

KAT5 KDM5A KDM5D

3.62e-045784318022353
Pubmed

Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity.

LRRC8D CYFIP2

3.75e-041284232277911
Pubmed

A family of 12 human genes containing oxysterol-binding domains.

OSBPL5 OSBPL8

3.75e-041284211735225
Pubmed

Kinase signalling in excitatory neurons regulates sleep quantity and depth.

HDAC9 HDAC5

3.75e-041284236477539
Pubmed

An oxysterol-binding protein family identified in the mouse.

OSBPL5 OSBPL8

3.75e-041284212215260
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

FBXW10B MTMR7 FBXW10 KAT5 CORO2A CPD EIF3C MMP13

3.89e-0473084834857952
Pubmed

Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development.

KDM5A KDM5D

4.42e-041384224619213
Pubmed

Analysis of BCL6-interacting proteins by tandem mass spectrometry.

HDAC9 HDAC5 CSMD1

4.64e-046284316147992
Pubmed

Histone deacetylase expression patterns in developing murine optic nerve.

HDAC9 HDAC5

5.15e-041484225011550
Pubmed

Modulation of smooth muscle gene expression by association of histone acetyltransferases and deacetylases with myocardin.

HDAC9 HDAC5

5.15e-041484215601857
Pubmed

Loss of all 3 Extended Synaptotagmins does not affect normal mouse development, viability or fertility.

OSBPL5 OSBPL8

5.15e-041484227399837
Pubmed

Identification of the ankyrin repeat proteins ANKRA and RFXANK as novel partners of class IIa histone deacetylases.

HDAC9 HDAC5

5.15e-041484215964851
Pubmed

Specific control of pancreatic endocrine β- and δ-cell mass by class IIa histone deacetylases HDAC4, HDAC5, and HDAC9.

HDAC9 HDAC5

5.15e-041484221953612
Pubmed

Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis.

HDAC9 HDAC5

5.15e-041484215537544
Pubmed

The laminin alpha chains: expression, developmental transitions, and chromosomal locations of alpha1-5, identification of heterotrimeric laminins 8-11, and cloning of a novel alpha3 isoform.

MAP3K8 LAMA5

5.15e-04148429151674
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ZNF462 KCTD12 AGO2 KDM5A ITSN1 DIAPH2 ADNP CABIN1 CYFIP2

5.30e-0496384928671696
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

ABCC1 EPB41L4B OSBPL8 RICTOR CPD CYFIP2

5.57e-0442184636976175
Pubmed

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

HDAC9 HDAC5 KDM5A KDM5D

5.82e-0415784430186101
Pubmed

Characterization of size-fractionated cDNA libraries generated by the in vitro recombination-assisted method.

TTC21B RICTOR

5.93e-041584212056414
Pubmed

The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.

SMCHD1 OSBPL8 DYSF CABIN1 GMPPA

6.09e-0428184524163370
GeneFamilyHistone deacetylases, class IIA

HDAC9 HDAC5

5.04e-054532992
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

PLEKHH1 ITSN1 OSBPL5 OSBPL8 ARAP1

3.37e-04206535682
GeneFamilyWD repeat domain containing|F-box and WD repeat domain containing

FBXW10B FBXW10

4.56e-0411532559
GeneFamilyOxysterol binding proteins|Pleckstrin homology domain containing

OSBPL5 OSBPL8

5.46e-0412532670
GeneFamilyAT-rich interaction domain containing

KDM5A KDM5D

8.64e-0415532418
GeneFamilyPHD finger proteins|Lysine demethylases

KDM5A KDM5D

2.23e-0324532485
GeneFamilyCalcium voltage-gated channel subunits

CACNA1I CACNA1G

2.62e-0326532253
CoexpressionIWANAGA_CARCINOGENESIS_BY_KRAS_PTEN_DN

TMTC1 ST6GALNAC3 ENPP2 SMCHD1 TTC21B PEX16 RICTOR FOXH1

2.19e-05363848M6315
CoexpressionIWANAGA_CARCINOGENESIS_BY_KRAS_PTEN_DN

TMTC1 ST6GALNAC3 ENPP2 SMCHD1 TTC21B PEX16 RICTOR FOXH1

2.60e-05372848MM1043
CoexpressionGSE8835_HEALTHY_VS_CLL_CD4_TCELL_UP

OGFRL1 TMTC1 KAT5 ITSN1 MMP13 DOP1B

4.41e-05199846M6260
CoexpressionGSE14769_UNSTIM_VS_60MIN_LPS_BMDM_DN

KCTD12 RNF103 MAP3K8 TLR2 STIL MMP13

4.54e-05200846M3499
CoexpressionGSE7852_TREG_VS_TCONV_UP

OGFRL1 ABCC1 CORO2A MAP3K8 CPD DNAH7

4.54e-05200846M5751
CoexpressionGSE7460_TCONV_VS_TREG_LN_DN

HDAC9 MTMR7 CORO2A MAP3K8 ASNS DNAH7

4.54e-05200846M5674
ToppCellCF|World / Disease state, Lineage and Cell class

MBOAT7 ST6GALNAC3 TLR2 CPD DYSF CYFIP2

1.48e-06187846eec4d4e4a658e3a61c05745167a1a5e3d39bb43e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HDAC9 OGFRL1 RIN3 MAP3K8 ITSN1 TLR2

1.83e-06194846c95d5c4ad0210ebd672926558cc8331e6396a854
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TMTC1 ST6GALNAC3 TUSC3 ANXA10 DYSF EPHX4

2.06e-0619884688b4662be9cc933a402c52673fa5e00fa979c0db
ToppCell3'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCTD12 TMTC1 ENPP2 LAMA5 C7 DYSF

2.12e-06199846f5c8ad751d21ea0b199a02846faecd04bf100033
ToppCellsevere-Neutrophil|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ROPN1L MBOAT7 SMCHD1 TLR2 CPD DYSF

2.18e-06200846f9af7e77a8483ab4ae708b55514e64f5420fa0c1
ToppCellsevere-Neutrophil|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ROPN1L MBOAT7 SMCHD1 TLR2 CPD DYSF

2.18e-06200846f04d5951bac4dee47c22aaf7973312ca797f322e
ToppCellCOVID-19-COVID-19_Severe-Myeloid-Neutrophil|COVID-19_Severe / Disease, condition lineage and cell class

ROPN1L MBOAT7 SMCHD1 TLR2 CPD DYSF

2.18e-06200846fec2660c9a9977b3b3a2eaed063b9049c0b07ff2
ToppCellLA-16._Neuronal|LA / Chamber and Cluster_Paper

KCTD12 OGFRL1 ST6GALNAC3 FAM135B ADGRL3

1.66e-05168845c55bbfbde8bb954f1cb9af82007bdd1f8070fee3
ToppCellCTRL-Myeloid-Neutrophil|Myeloid / Disease state, Lineage and Cell class

MBOAT7 SMCHD1 TLR2 CPD DYSF

1.76e-05170845151dabe1d240dde414c881bf4fa816c69fa1c32d
ToppCellCTRL-Myeloid-Neutrophil|CTRL / Disease state, Lineage and Cell class

MBOAT7 SMCHD1 TLR2 CPD DYSF

1.86e-05172845ef3a6fe3b7300959f9f71130200c7fb8741c42b0
ToppCellCF-Myeloid-Neutrophil|Myeloid / Disease state, Lineage and Cell class

ST6GALNAC3 SMCHD1 CPD DYSF CYFIP2

2.02e-051758458020c3a34f77e68e8149f87481fb1dddd2ac675e
ToppCellCOVID-19-Endothelial_cells-Endothelial_cells_(other)|COVID-19 / group, cell type (main and fine annotations)

TMTC1 ST6GALNAC3 TUSC3 LAMA5 ADGRL3

2.38e-0518184526eb4ee57a70dbf54e096b73129fda9dfda1f6ec
ToppCell3'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCTD12 TMTC1 ENPP2 LAMA5 C7

2.44e-05182845d996ceb77c83591df4cef144ca72862f31d9777f
ToppCellCF-Myeloid-Neutrophil|CF / Disease state, Lineage and Cell class

ST6GALNAC3 TLR2 CPD DYSF CYFIP2

2.51e-05183845da43827952e6fdee2ce94648c316182f272b321c
ToppCellCOPD-Myeloid-cMonocyte|World / Disease state, Lineage and Cell class

RIN3 MAP3K8 ST6GALNAC3 TLR2 CSMD1

2.57e-05184845ceec41ed5636032aaf7716d1203816ea58bd39bd
ToppCellCOVID-19-Endothelial_cells-Arterial_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

TMTC1 ST6GALNAC3 ENPP2 TUSC3 CSMD1

2.57e-051848450f19494789f38ab1a420545e15e748ca7eb345c3
ToppCellIPF-Myeloid-DC_Langerhans|IPF / Disease state, Lineage and Cell class

HDAC9 NAALADL1 ENPP2 CACNA1G CYFIP2

2.64e-05185845f8ee3cb2aa9ec70f9ce8797be2b155da27ef6464
ToppCellCOVID_non-vent-Myeloid-Monocytic-Neutrophil|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

ROPN1L MBOAT7 SMCHD1 OSBPL8 DYSF

2.64e-051858452c89af7cdf5306b900a5b8ec4fdfb8210e5667ed
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KCTD12 RIN3 CACNA1G C7 CABIN1

2.64e-051858451ac6a32cc56d5d819649bdd99518e2ead0eead4c
ToppCell3'-Adult-Appendix-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCTD12 TMTC1 ENPP2 LAMA5 EPHX4

2.78e-0518784537d8ee5c8bd6324749e5a2adef1d0482c75da80c
ToppCell3'-Adult-Appendix-Endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCTD12 TMTC1 ENPP2 LAMA5 EPHX4

2.78e-05187845ec98d5e480b08854dfd0ba6b1dc6610455f90640
ToppCellpdx-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ZNF462 ABCC1 LAMA5 CACNA1I CABIN1

2.78e-051878457e376831a11ee72ed87abcdac631ca46ae29c250
ToppCelldroplet-Pancreas|droplet / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PNLIPRP1 ENPP2 ASNS UNC80 CYFIP2

2.78e-051878455f4df092452d8672bda4059c794e099ba3f5a8fa
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ROPN1L MBOAT7 SMCHD1 TLR2 CPD

2.78e-0518784575bc05a0ba2727fecc236903ace792a28f3d3c9a
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ROPN1L MBOAT7 SMCHD1 TLR2 CPD

2.78e-05187845a0d59bf1043ff5a1e8110b39ecc2d3932675edd4
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TMTC1 ENPP2 TUSC3 MMP13 P3H4

2.85e-05188845ed92cddf47defea2f904d36c7ae05ffa323349a9
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ROPN1L MBOAT7 SMCHD1 TLR2 DYSF

2.85e-05188845aa46073e2940dc1d2020b2e259bf0fc06cb990ee
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ROPN1L MBOAT7 SMCHD1 TLR2 DYSF

2.85e-0518884504814b78da936a51a497e23060d19ca0d619e250
ToppCellCOPD-Myeloid-cMonocyte|COPD / Disease state, Lineage and Cell class

RIN3 MAP3K8 ST6GALNAC3 TLR2 DYSF

2.93e-05189845d29f3a0bd23e6eb46389e6eb7ef21851c7b57545
ToppCellCOVID-19_Severe-Myeloid_G-Neutrophil|COVID-19_Severe / Disease group, lineage and cell class

ROPN1L MBOAT7 SMCHD1 TLR2 DYSF

2.93e-05189845a62f4c445ede00d15b74bee65f4e4fb54cfd4d32
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ROPN1L MBOAT7 SMCHD1 TLR2 DYSF

2.93e-05189845f6b2b4824505f0119a017fdb73c55418fb651645
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ROPN1L MBOAT7 SMCHD1 TLR2 DYSF

2.93e-05189845db8e314ce95c32542bb4015a77032a33211fea0b
ToppCellIPF-Myeloid-ncMonocyte|Myeloid / Disease state, Lineage and Cell class

TMTC1 RIN3 ST6GALNAC3 SMCHD1 CYFIP2

2.93e-051898455c22d2d935f7bb270260b8bc6be67b565ec401bf
ToppCellCOPD-Myeloid-ncMonocyte|Myeloid / Disease state, Lineage and Cell class

TMTC1 RIN3 ST6GALNAC3 SMCHD1 CYFIP2

3.00e-05190845ed978cd5d9da87b49878a330e362762c487f849f
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-AEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TMTC1 ST6GALNAC3 ENPP2 TUSC3 CSMD1

3.08e-0519184550601ef0a5a8f2c2120922989e08e85bf2d9b4ab
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ROPN1L MBOAT7 TLR2 CPD DYSF

3.08e-05191845b9b091d6b352d5128bb864ff52d2e5fb3387b766
ToppCellControl-Myeloid-ncMonocyte|Myeloid / Disease state, Lineage and Cell class

TMTC1 RIN3 ST6GALNAC3 SMCHD1 CYFIP2

3.23e-051938453479c01aaae7afd7e02d00e0cb21951c0106a0fd
ToppCellCOVID-19-Endothelial_cells-Inflamed_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

ST6GALNAC3 TUSC3 LAMA5 DYSF ADGRL3

3.23e-05193845979ebefa527f86bebeea5d94e626ee6c1cc7d53b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KCTD12 TMTC1 ST6GALNAC3 ENPP2 DYSF

3.23e-051938456a623acd1adad9a78eddc32ffedb16352ad3fdfa
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HDAC9 TMTC1 ST6GALNAC3 ENPP2 DYSF

3.23e-05193845287e756d5fd3bd2931c168da24beaa0d02a350ae
ToppCellsevere-Myeloid-Neutrophils_3|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

ROPN1L MBOAT7 OSBPL8 CPD DYSF

3.32e-051948451f8edab1c8ba48bc0114429ea47aab378b5830b7
ToppCellmild-Myeloid-Neutrophils_1|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

OGFRL1 MBOAT7 SMCHD1 DYSF ARAP1

3.32e-05194845ccd911ce3251cd1c60f1fb2ce00650fbe7a379bb
ToppCellCOVID-19-kidney-PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

TMTC1 RIN3 ST6GALNAC3 SMCHD1 DYSF

3.40e-05195845a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

EPB41L4B CPD CSMD1 DYSF UNC80

3.40e-05195845d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellChildren_(3_yrs)-Immune-monocyte-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

HDAC9 RIN3 ST6GALNAC3 TLR2 DYSF

3.40e-0519584581a28289eda1a8a1a31b7357106f64ac5000e172
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

EPB41L4B CPD CSMD1 DYSF UNC80

3.40e-0519584519853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCellCF-Myeloid|CF / Disease state, Lineage and Cell class

MBOAT7 ST6GALNAC3 TLR2 CPD DYSF

3.40e-05195845ecf604de496f389a49429d0bb211e1db6019cc8b
ToppCelltumor_Lung-Endothelial_cells-Stalk-like_ECs|Endothelial_cells / Location, Cell class and cell subclass

HDAC9 KCTD12 TMTC1 MAP3K8 C7

3.40e-0519584556f88ce95495260360bf08f9c76cc36e395dc6a9
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FICD ENPP2 ASNS UQCC2 CYFIP2

3.40e-0519584558b769da05a8f6b05aeb08d4f8b112941087ad00
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TMTC1 ST6GALNAC3 ENPP2 TUSC3 DYSF

3.48e-05196845915e4a7422058be246b54760df31e8a607310625
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TMTC1 RIN3 ST6GALNAC3 ENPP2 DYSF

3.48e-05196845b8f89a50114932c08fc5daac4b549adfe9df8e66
ToppCellmild-Myeloid-Neutrophils_3|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

ROPN1L MBOAT7 SMCHD1 OSBPL8 DYSF

3.48e-051968459c351306b6aae68ed47d4cb1911957bf67f9e1ae
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HDAC9 OGFRL1 RIN3 MAP3K8 TLR2

3.48e-05196845cbc727b55b6433a701b1a331028a49960fcee6ee
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TMTC1 RIN3 ST6GALNAC3 ENPP2 DYSF

3.48e-05196845145fcf73deba9638b391a1af6c39fa205dc9829f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TMTC1 RIN3 ST6GALNAC3 ENPP2 DYSF

3.48e-05196845d0ff1082898d2db47c88d2678466514e9e9193d3
ToppCellPBMC-Control-cDC_3|Control / Compartment, Disease Groups and Clusters

KCTD12 KDM5A CHD1L EIF3C CYFIP2

3.48e-0519684509d197b321ff9f13c0672ea059c850845b0dbbd5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HDAC9 OGFRL1 RIN3 MAP3K8 TLR2

3.57e-051978456ca6e17b7cc5f7ea8d4b6ca1ff670969bee65a45
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ST6GALNAC3 ENPP2 LAMA5 FAM135B ADGRL3

3.57e-05197845ea746772adb9df4ddb0508d4ef35f2027bf09c35
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MBOAT7 SMCHD1 TLR2 CPD DYSF

3.57e-05197845340ce4fef244176fb52e38ffbcbdfda5ac3467dd
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HDAC9 OGFRL1 RIN3 MAP3K8 TLR2

3.57e-05197845dea1d29154c585ab588e50b83c7c8de7fe24d2d4
ToppCellbackground-Kupffer_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

HDAC9 KCTD12 RIN3 MAP3K8 TLR2

3.57e-051978458b45c7ecc18d188abc8c172d9bf881c95617a46a
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KCTD12 OGFRL1 MBOAT7 TLR2 DYSF

3.57e-05197845928d70af7b990300be69a4debce6e66b556e5d9f
ToppCellCOVID-19_Moderate-cDC|COVID-19_Moderate / disease group, cell group and cell class

HDAC9 KCTD12 OGFRL1 MBOAT7 MAP3K8

3.57e-05197845ff45a212434a1b128e1a217c6abdec6380938da9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HDAC9 OGFRL1 RIN3 MAP3K8 TLR2

3.57e-0519784572cd61b868d57862ec9c230ea68913d3829b0f2b
ToppCellmild-Myeloid|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

KCTD12 OGFRL1 MBOAT7 TLR2 DYSF

3.65e-05198845908746384e10c6b833bb3bc124045d7b0bfd73b5
ToppCellTracheal-NucSeq-Endothelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KCTD12 TMTC1 ST6GALNAC3 ENPP2 DYSF

3.65e-0519884577e31b6edeeb5ccd5cd3f080898c96bf9ab9f98d
ToppCellCOVID-19-lung-Capillary_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

TMTC1 ST6GALNAC3 LAMA5 CSMD1 DYSF

3.65e-0519884545419f2804b4be79bae6632e71c54e1af482d115
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TMTC1 ST6GALNAC3 ENPP2 TUSC3 DYSF

3.65e-05198845002424b24dacac553e02d0f764a6e8a1e567b9df
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_venous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HDAC9 TMTC1 ST6GALNAC3 NMRK2 DYSF

3.74e-05199845e2d5c5cab102e67b0131b02392d81adaedc15965
ToppCellControl-Control-Myeloid-Neutrophil|Control / Disease, condition lineage and cell class

OGFRL1 ROPN1L MBOAT7 SMCHD1 DYSF

3.83e-0520084595c41f147a1594d49e73cb56d86d301c3115ce20
ToppCellParenchyma_COVID-19-Endothelial-TX-Artery|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

KCTD12 TMTC1 ST6GALNAC3 ENPP2 TUSC3

3.83e-0520084534b279804475ea58fbb052b96f44128c082627a9
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Artery|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

KCTD12 TMTC1 ST6GALNAC3 ENPP2 TUSC3

3.83e-052008458552cc7a439449b30b59760c3e8667217b9852b5
ToppCellcellseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

HDAC9 KCTD12 TMTC1 ENPP2 C7

3.83e-05200845a1f5684fe3815642159dd201b7ecc39f09bee1e8
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MBOAT7 SMCHD1 TLR2 CPD DYSF

3.83e-052008456beabd5bad042d4d65c89c2f537c7376230f7c08
ToppCellInfluenza|World / Disease, condition lineage and cell class

KCTD12 MBOAT7 MAP3K8 TLR2 DYSF

3.83e-05200845df996c35907a1c9194b9e2ca30e81f520ca067f0
ToppCellsevere-HLA-DR-_S100A+_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

KCTD12 MAP3K8 TLR2 CPD DYSF

3.83e-05200845db7046741706376682d164c385c4701aebefc2e6
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MBOAT7 SMCHD1 TLR2 CPD DYSF

3.83e-05200845026495aa7f1e7528a01d9199475cfc393677fc60
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Artery-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KCTD12 TMTC1 ST6GALNAC3 ENPP2 TUSC3

3.83e-0520084545c08f1befe78553bbadcc2fcffb6138306638f3
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-MyoFB-3|PND07-28-samps / Age Group, Lineage, Cell class and subclass

P3H1 OSBPL5 CACNA1G GMPPA

1.47e-041418447ae8ead02e5aeb4106c4a30c08a7a061da3a5d6a
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

KCTD12 CACNA1G LRRC8D P3H4

1.81e-0414984413b445c13bb8f31ff0876addd1baf969ae220ea3
ToppCellRV-16._Neuronal|World / Chamber and Cluster_Paper

KCTD12 OGFRL1 FAM135B ADGRL3

1.81e-041498443a2f8c4173dcf9e3f8d3b8ffddbc597098adf7a9
ToppCellRV-16._Neuronal|RV / Chamber and Cluster_Paper

KCTD12 OGFRL1 FAM135B ADGRL3

2.01e-04153844bed8bbf5c5cbfbf46a816066da472c3fdddecb5d
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

ABCC1 PNLIPRP1 SMCHD1 RICTOR

2.16e-041568441545169694f686d28648a68b552c2ae606599d66
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAALADL1 CSMD1 MMP13 CWF19L1

2.22e-041578441f21d78a467fe22c5ab75d0917b840c1ac93f32c
ToppCell356C-Lymphocytic-NK_cells-NK_cell_A2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

HDAC9 TMPRSS9 TLR2 LAMA5

2.44e-041618448ec923c230a7a3cce5edf2a736b3a00d607c698a
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

MBOAT7 TPRG1 ZFC3H1 STIL

2.44e-0416184458381131e651744b5141b202f9d6063f55432db5
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel|Children_(3_yrs) / Lineage, Cell type, age group and donor

ST6GALNAC3 ENPP2 DYSF ADGRL3

2.56e-04163844977a970b1296234c22178420294cea73506ee02f
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid-neutrophil|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCTD12 OGFRL1 AGO2 CYFIP2

2.62e-041648448e6dbddacd56a07769163813e3ebfad13302bb62
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TMTC1 NAALADL1 ENPP2 DYSF

2.74e-04166844ec719368295133da2f7ff587c5329ed6db1dd56d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TMTC1 ST6GALNAC3 ENPP2 DYSF

2.74e-041668448e2faca6a2e76a625de04d6098aa6f98911945c6
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

HDAC9 TMTC1 ST6GALNAC3 C7

2.80e-04167844d7fe24cdc4b55a9555ce9e20699f5036b88148e9
ToppCellLA-16._Neuronal|World / Chamber and Cluster_Paper

KCTD12 OGFRL1 FAM135B ADGRL3

2.87e-041688442fd1fd2a16ac1c5eb028f93cc3a2477c7747693e
ToppCellhealthy_donor-Myeloid-Monocytic-Neutrophil|healthy_donor / Disease condition, Lineage, Cell class and subclass

ROPN1L MBOAT7 SMCHD1 DYSF

2.87e-0416884404259f5a9b067cd1b5619e34591e4b2fccc18535
ToppCellInfluenza_Severe-Neutrophil|World / Disease group and Cell class

PLEKHH1 ROPN1L MBOAT7 TLR2

2.93e-041698446e8e2580e19c96bcf7fa6a6d8c183df65f428396
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

TMTC1 ST6GALNAC3 ENPP2 CSMD1

3.07e-041718441597459c971d6befa991d59dc66b41b6a522f797
ToppCell368C-Endothelial_cells-Endothelial-B_(Artery)-|368C / Donor, Lineage, Cell class and subclass (all cells)

TMTC1 ENPP2 TUSC3 LAMA5

3.21e-04173844ec88e871b49331fca59bc610a8ae58e2d5e76bc1
ToppCell368C-Endothelial_cells-Endothelial-B_(Artery)|368C / Donor, Lineage, Cell class and subclass (all cells)

TMTC1 ENPP2 TUSC3 LAMA5

3.21e-0417384422200fe74e33e2beae0eed289ca8476bbc0b1b2d
ToppCell3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMTC1 ENPP2 C7 DYSF

3.21e-04173844b57d14e2c2368304cb903562d06ce8228f53857c
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Chat_Htr1f|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HDAC9 KCTD12 ENPP2 LAMA5

3.28e-04174844a5f2a4e3b25e6084bd7003a53da86a44f6fcf294
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TMTC1 ST6GALNAC3 ENPP2 DYSF

3.28e-041748443d4c05ea5719ca65e85d1f15198453034791087c
Druganacardic acid

HDAC9 KAT5 HDAC5 CACNA1I CACNA1G

8.03e-0830845CID000167551
DrugChloroprene

ZNF462 HDAC9 ABCC1 ROPN1L TMTC1 RIN3 AGO2 PNLIPRP1 KDM5A CORO2A ST6GALNAC3 SMCHD1 PPHLN1 CPD EIF3C STIL ADGRL3

7.11e-0613488417ctd:D002737
Diseasesyndromic X-linked intellectual disability Claes-Jensen type (implicated_via_orthology)

KDM5A KDM5D

4.67e-054832DOID:0060809 (implicated_via_orthology)
Diseasecis-4-decenoylcarnitine (C10:1) measurement

ABCC1 ST6GALNAC3

2.16e-048832EFO_0800311
DiseaseLiver Cirrhosis, Experimental

PLEKHH1 MTMR7 MAP3K8 ENPP2 TUSC3 ASNS C7 MMP13 DYSF

3.27e-04774839C0023893
Diseasecystic kidney disease (implicated_via_orthology)

TTC21B LAMA5

3.47e-0410832DOID:2975 (implicated_via_orthology)
Diseaseserum selenium measurement

MTMR7 CSMD1 FAM135B

4.54e-0453833EFO_0005266
Diseasedecanoylcarnitine measurement

ABCC1 ST6GALNAC3

5.07e-0412832EFO_0021039
Diseaseovarian carcinoma (is_implicated_in)

MMP13 CABIN1

8.02e-0415832DOID:4001 (is_implicated_in)
Diseasesyndromic intellectual disability (implicated_via_orthology)

KDM5A KDM5D

9.14e-0416832DOID:0050888 (implicated_via_orthology)
Diseaseproliferative diabetic retinopathy (is_marker_for)

MAP3K8 ENPP2

9.14e-0416832DOID:13207 (is_marker_for)
Diseaseintellectual disability (implicated_via_orthology)

KDM5A ITSN1 KDM5D

1.25e-0375833DOID:1059 (implicated_via_orthology)
Diseaseresponse to methotrexate, juvenile idiopathic arthritis

CACNA1I CSMD1

1.30e-0319832EFO_0002609, GO_0031427
Diseasephosphatidylethanolamine measurement

ANO9 PNLIPRP1 TUSC3 MMP13

1.46e-03173834EFO_0010228
Diseasefeeling nervous measurement

ASNS CSMD1 PIGU

1.92e-0387833EFO_0009597
Diseaseresponse to peginterferon alfa-2a

HDAC9 CORO2A

2.25e-0325832EFO_0010103
Diseasepsychosis predisposition measurement

ABCC1 CSMD1

2.43e-0326832EFO_0008337
DiseasePR interval

HDAC9 PPHLN1 CACNA1G DYSF P3H4 ADGRL3

2.75e-03495836EFO_0004462

Protein segments in the cluster

PeptideGeneStartEntry
KRYGSDPVFRFYHAY

TTC21B

31

Q7Z4L5
TYRDPLYEIVRKHIY

ADNP

171

Q9H2P0
LRVPFLDHRFSSYYL

ASNS

416

P08243
RDKPAYFAYRLYSAI

ANXA10

246

Q9UJ72
LSGFAFYLYKHRTRP

CSMD1

3501

Q96PZ7
SPAYAIRSYAYLLLH

ALG9

106

Q9H6U8
FSKYRDFIRYLPIHL

FBXW10

271

Q5XX13
ESEHSRRKYFYLVGY

ADGRL3

961

Q9HAR2
PDYKLRPYQHSYLRS

ANO9

316

A1A5B4
HFLLIRNDYYIRPQY

DIAPH2

431

O60879
APAYYAHLVAFRARY

AGO2

801

Q9UKV8
SYFRLDTPLYFSYSH

P3H1

551

Q32P28
FSKYRDFIRYLPIHL

FBXW10B

271

O95170
RSFYAARDLYKYRHQ

OGFRL1

91

Q5TC84
KRYLRHDKPPYTYLA

FOXH1

26

O75593
RRFPVLSYYYKDNHA

MTMR7

186

Q9Y216
RHPAQLLKSSYYYFF

EPHX4

206

Q8IUS5
YFYYKFRTRPSLLSA

SLC66A1

116

Q6ZP29
SFLRSYYPCYLKVSH

DOP1B

1321

Q9Y3R5
ISRLLYYVFPYLRNH

DOP1B

1926

Q9Y3R5
YLYTRALTISPYHEK

FICD

161

Q9BVA6
HKTLYYDTDPFLFYV

KAT5

326

Q92993
SLLRSHYERIIYPYE

KDM5D

151

Q9BY66
ALEKTYYERLPYRNH

CWF19L1

196

Q69YN2
YPRSAYPSYLYIIHK

MAP3K8

331

P41279
HLRSYKYYLESILNP

PNLIPRP1

281

P54315
LQFAERYLRSYYHPT

MMP13

36

P45452
YIYKSAPARSYVLRS

MBOAT7

331

Q96N66
KALRDPTVTRRYYYS

LAMA5

276

O15230
KPLNIAYSHIYSSYR

CYFIP2

916

Q96F07
HRFVRRLLYFYKPSS

RICTOR

571

Q6R327
RREYYLTHGLYLTAK

PIGU

411

Q9H490
SLLKSHYERILYPYE

KDM5A

156

P29375
EPRSFLDKLSDYYYH

OSBPL8

431

Q9BZF1
RIYLLRILHTYYKFD

EIF3C

501

Q99613
YASRLYLSRYQDTHP

GMPPA

256

Q96IJ6
SRFPQHYKSLYRLAF

CABIN1

1521

Q9Y6J0
YRLAFLYTYSKTHRN

CABIN1

1531

Q9Y6J0
KPYYSDYSRFRLLVH

CACNA1G

1591

O43497
RLPYYATYCHTRLLI

CACNA1I

1466

Q9P0X4
YSLPYKHTPYRVLRN

GUCY2F

286

P51841
KVVYYRALYPFESRS

ITSN1

741

Q15811
KHLAARGIPTYIYYF

CHD1L

861

Q86WJ1
YIYYFPRSKSAVLHS

CHD1L

871

Q86WJ1
SHLPSLYDYSAYRRL

C7

281

P10643
RYYEVSADKPHLSYL

CORO2A

296

Q92828
DFRFYITTKLRNPHY

DNAH7

3076

Q8WXX0
YRYHSYKDLSEFLRG

CPD

931

O75976
LDPKEHSYYYRPART

C5orf49

36

A4QMS7
PRFRYYLNKLHTFLS

FAM135B

1231

Q49AJ0
FYNDPSVLYISLHRY

HDAC5

881

Q9UQL6
FYADPSILYISLHRY

HDAC9

831

Q9UKV0
PYLDSFYEYSLKLLR

RNF103

381

O00237
YALHFRVKYYSSEPN

EPB41L4B

156

Q9H329
YLRRRKYSLFAAFYS

DYSF

586

O75923
RPPERYTSRYYLKFN

KCTD12

261

Q96CX2
FYSSHYARERSPYKR

PPHLN1

111

Q8NEY8
RPAVLYRTRYDILYH

ENPP2

601

Q13822
YSKYFPYLALIHTII

LRRC8D

161

Q7L1W4
YLLRSEPKRDFHFVY

RIN3

946

Q8TB24
PRSFLNKLSDYYYHA

OSBPL5

396

Q9H0X9
PFYFLYLSRHDRGYI

ABCC1

51

P33527
SYKPLVDLYSRRYFL

NMRK2

106

Q9NPI5
LLYYLLRSPFYDRFS

PEX16

281

Q9Y5Y5
IIRYHPFLYDRETYP

SMCHD1

426

A6NHR9
YKSQVFSYPHRYLVL

TMEM80

116

Q96HE8
AADLSLYPHLYSRAY

UPF3A

101

Q9H1J1
LYPHLYSRAYINFRN

UPF3A

106

Q9H1J1
SYTYRRPLRTHYGYI

ST6GALNAC3

51

Q8NDV1
RYLYFSSTKLRAPNY

MTRES1

41

Q9P0P8
EAKYREGKYRRYHPL

ARAP1

641

Q96P48
DFIYLHLSYYRNPKL

STIL

41

Q15468
SIFRSKYHGYPYSDL

TUSC3

331

Q13454
IHYNKTYVRDIYPFR

UNC80

2051

Q8N2C7
EAIYHYRTALKLYPR

TMTC1

501

Q8IUR5
ARIPFKTFSYVYRYL

ROPN1L

161

Q96C74
PVDSKRYRYVYHSSQ

TBX22

146

Q9Y458
LRDFQSRLPYQYLHY

P3H4

136

Q92791
SRLPYQYLHYALFKA

P3H4

141

Q92791
PYHQPYISRKYFATR

TPRG1

56

Q6ZUI0
ERVARIYKHPFYNLY

TMPRSS9

896

Q7Z410
NYYKHKYPRPRDTSF

UQCC2

66

Q9BRT2
SFLSQYRYYTPAKRK

SPATA7

251

Q9P0W8
LRRPKYTIYFIYFSN

VPS45

86

Q9NRW7
GKIFYYYRSHEDKRP

PLEKHH1

711

Q9ULM0
NAHLTYKFLTPYLYD

TTC30A

346

Q86WT1
SYTSPYFYALRKHIK

ZNF462

1271

Q96JM2
RLHIPRFYLFYDLST

TLR2

316

O60603
LPGFYHLRIAYYASK

TMEM230

91

Q96A57
LVFKSYRFSPYYRTK

ZFC3H1

1151

O60293
YDRSKTSARIYPTYH

NAALADL1

531

Q9UQQ1