| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | monoatomic ion transmembrane transporter activity | SLC6A6 BEST1 ATP7B SLC24A4 BEST2 BEST4 PKD1L1 SLC6A20 PKD1 KCNMB1 BEST3 ATP13A5 PANX1 NIPA1 ANO10 SLC5A12 SLC5A8 SLC1A3 SLC30A10 ANO3 PANX3 RYR1 RYR2 RYR3 KCNH3 | 9.39e-19 | 793 | 65 | 25 | GO:0015075 |
| GeneOntologyMolecularFunction | inorganic molecular entity transmembrane transporter activity | SLC6A6 BEST1 ATP7B SLC24A4 BEST2 BEST4 PKD1L1 SLC6A20 PKD1 KCNMB1 BEST3 PANX1 NIPA1 ANO10 SLC5A12 SLC5A8 SLC1A3 SLC30A10 ANO3 PANX3 RYR1 RYR2 RYR3 KCNH3 | 5.12e-18 | 758 | 65 | 24 | GO:0015318 |
| GeneOntologyMolecularFunction | transporter activity | SLC6A6 BEST1 ATP7B SLC24A4 BEST2 BEST4 PKD1L1 SLC6A20 SLC6A19 PKD1 KCNMB1 BEST3 ATP13A5 PANX1 APOB NIPA1 ANO10 SLC5A12 SLC5A8 SLC1A3 SLC30A10 ANO3 PANX3 RYR1 RYR2 RYR3 KCNH3 | 7.56e-16 | 1289 | 65 | 27 | GO:0005215 |
| GeneOntologyMolecularFunction | transmembrane transporter activity | SLC6A6 BEST1 ATP7B SLC24A4 BEST2 BEST4 PKD1L1 SLC6A20 SLC6A19 PKD1 KCNMB1 BEST3 ATP13A5 PANX1 NIPA1 ANO10 SLC5A12 SLC5A8 SLC1A3 SLC30A10 ANO3 PANX3 RYR1 RYR2 RYR3 KCNH3 | 9.50e-16 | 1180 | 65 | 26 | GO:0022857 |
| GeneOntologyMolecularFunction | monoatomic cation transmembrane transporter activity | SLC6A6 ATP7B SLC24A4 BEST2 PKD1L1 SLC6A20 PKD1 KCNMB1 ATP13A5 PANX1 NIPA1 ANO10 SLC5A12 SLC5A8 SLC1A3 SLC30A10 PANX3 RYR1 RYR2 RYR3 KCNH3 | 1.02e-15 | 664 | 65 | 21 | GO:0008324 |
| GeneOntologyMolecularFunction | metal ion transmembrane transporter activity | SLC6A6 ATP7B SLC24A4 PKD1L1 SLC6A20 PKD1 KCNMB1 PANX1 NIPA1 SLC5A12 SLC5A8 SLC1A3 SLC30A10 PANX3 RYR1 RYR2 RYR3 KCNH3 | 5.32e-15 | 465 | 65 | 18 | GO:0046873 |
| GeneOntologyMolecularFunction | passive transmembrane transporter activity | BEST1 SLC24A4 BEST2 BEST4 PKD1L1 PKD1 KCNMB1 BEST3 PANX1 ANO10 SLC5A8 ANO3 PANX3 RYR1 RYR2 RYR3 KCNH3 | 6.37e-13 | 526 | 65 | 17 | GO:0022803 |
| GeneOntologyMolecularFunction | inorganic cation transmembrane transporter activity | SLC6A6 ATP7B SLC24A4 PKD1L1 SLC6A20 PKD1 KCNMB1 PANX1 NIPA1 SLC5A12 SLC5A8 SLC1A3 SLC30A10 PANX3 RYR1 RYR2 RYR3 KCNH3 | 8.71e-13 | 627 | 65 | 18 | GO:0022890 |
| GeneOntologyMolecularFunction | monoatomic ion channel activity | BEST1 SLC24A4 BEST2 BEST4 PKD1L1 PKD1 KCNMB1 BEST3 PANX1 ANO10 ANO3 PANX3 RYR1 RYR2 RYR3 KCNH3 | 1.08e-12 | 459 | 65 | 16 | GO:0005216 |
| GeneOntologyMolecularFunction | olfactory receptor activity | OR5P3 OR6V1 OR10H5 OR9K2 OR10H2 OR10H1 OR2G3 OR6J1 OR52E4 OR4C46 OR1K1 OR5A2 OR5H14 OR2T10 OR6T1 | 6.25e-12 | 431 | 65 | 15 | GO:0004984 |
| GeneOntologyMolecularFunction | channel activity | BEST1 SLC24A4 BEST2 BEST4 PKD1L1 PKD1 KCNMB1 BEST3 PANX1 ANO10 ANO3 PANX3 RYR1 RYR2 RYR3 KCNH3 | 8.21e-12 | 525 | 65 | 16 | GO:0015267 |
| GeneOntologyMolecularFunction | G protein-coupled receptor activity | OR5P3 OR6V1 OR10H5 DRD3 OR9K2 OR10H2 OR10H1 OR2G3 OR6J1 GPR82 OR52E4 OR4C46 OR1K1 OR5A2 OR5H14 OR2T10 OR6T1 GPR176 OPRK1 | 2.80e-11 | 884 | 65 | 19 | GO:0004930 |
| GeneOntologyMolecularFunction | ligand-gated monoatomic ion channel activity | 6.36e-10 | 193 | 65 | 10 | GO:0015276 | |
| GeneOntologyMolecularFunction | ligand-gated channel activity | 7.77e-10 | 197 | 65 | 10 | GO:0022834 | |
| GeneOntologyMolecularFunction | monoatomic cation channel activity | SLC24A4 BEST2 PKD1L1 PKD1 KCNMB1 PANX1 ANO10 PANX3 RYR1 RYR2 RYR3 KCNH3 | 9.70e-10 | 343 | 65 | 12 | GO:0005261 |
| GeneOntologyMolecularFunction | calcium ion transmembrane transporter activity | 1.42e-09 | 151 | 65 | 9 | GO:0015085 | |
| GeneOntologyMolecularFunction | intracellularly calcium-gated channel activity | 4.66e-09 | 20 | 65 | 5 | GO:0141147 | |
| GeneOntologyMolecularFunction | intracellularly calcium-gated chloride channel activity | 4.66e-09 | 20 | 65 | 5 | GO:0005229 | |
| GeneOntologyMolecularFunction | transmembrane signaling receptor activity | OR5P3 OR6V1 OR10H5 DRD3 OR9K2 OR10H2 OR10H1 OR2G3 OR6J1 GPR82 PKD1 OR52E4 OR4C46 OR1K1 OR5A2 OR5H14 OR2T10 OR6T1 GPR176 OPRK1 | 5.41e-09 | 1353 | 65 | 20 | GO:0004888 |
| GeneOntologyMolecularFunction | calcium channel activity | 9.03e-09 | 129 | 65 | 8 | GO:0005262 | |
| GeneOntologyMolecularFunction | gated channel activity | BEST1 BEST2 BEST4 KCNMB1 BEST3 ANO10 ANO3 RYR1 RYR2 RYR3 KCNH3 | 9.74e-09 | 334 | 65 | 11 | GO:0022836 |
| GeneOntologyMolecularFunction | ligand-gated monoatomic anion channel activity | 1.33e-08 | 50 | 65 | 6 | GO:0099095 | |
| GeneOntologyMolecularFunction | monoatomic anion transmembrane transporter activity | 3.11e-08 | 151 | 65 | 8 | GO:0008509 | |
| GeneOntologyMolecularFunction | bicarbonate channel activity | 3.29e-08 | 3 | 65 | 3 | GO:0160133 | |
| GeneOntologyMolecularFunction | monoatomic anion channel activity | 4.31e-08 | 103 | 65 | 7 | GO:0005253 | |
| GeneOntologyMolecularFunction | organic acid:sodium symporter activity | 9.41e-08 | 35 | 65 | 5 | GO:0005343 | |
| GeneOntologyMolecularFunction | ryanodine-sensitive calcium-release channel activity | 1.31e-07 | 4 | 65 | 3 | GO:0005219 | |
| GeneOntologyMolecularFunction | chloride transmembrane transporter activity | 1.64e-07 | 125 | 65 | 7 | GO:0015108 | |
| GeneOntologyMolecularFunction | chloride channel activity | 3.60e-07 | 86 | 65 | 6 | GO:0005254 | |
| GeneOntologyMolecularFunction | organic anion transmembrane transporter activity | SLC6A6 BEST1 BEST2 BEST4 SLC6A20 PANX1 SLC5A12 SLC5A8 SLC1A3 | 4.34e-07 | 293 | 65 | 9 | GO:0008514 |
| GeneOntologyMolecularFunction | active monoatomic ion transmembrane transporter activity | SLC6A6 ATP7B SLC24A4 SLC6A20 ATP13A5 SLC5A12 SLC5A8 SLC1A3 SLC30A10 | 5.44e-07 | 301 | 65 | 9 | GO:0022853 |
| GeneOntologyMolecularFunction | symporter activity | 5.67e-07 | 150 | 65 | 7 | GO:0015293 | |
| GeneOntologyMolecularFunction | calcium-induced calcium release activity | 6.54e-07 | 6 | 65 | 3 | GO:0048763 | |
| GeneOntologyMolecularFunction | inorganic anion transmembrane transporter activity | 1.37e-06 | 171 | 65 | 7 | GO:0015103 | |
| GeneOntologyMolecularFunction | active transmembrane transporter activity | SLC6A6 ATP7B SLC24A4 SLC6A20 SLC6A19 ATP13A5 SLC5A12 SLC5A8 SLC1A3 SLC30A10 | 3.04e-06 | 477 | 65 | 10 | GO:0022804 |
| GeneOntologyMolecularFunction | intracellularly ligand-gated monoatomic ion channel activity | 3.90e-06 | 33 | 65 | 4 | GO:0005217 | |
| GeneOntologyMolecularFunction | secondary active transmembrane transporter activity | SLC6A6 SLC24A4 SLC6A20 SLC6A19 SLC5A12 SLC5A8 SLC1A3 SLC30A10 | 5.15e-06 | 296 | 65 | 8 | GO:0015291 |
| GeneOntologyMolecularFunction | ligand-gated monoatomic cation channel activity | 6.27e-06 | 140 | 65 | 6 | GO:0099094 | |
| GeneOntologyMolecularFunction | solute:sodium symporter activity | 6.62e-06 | 81 | 65 | 5 | GO:0015370 | |
| GeneOntologyMolecularFunction | neutral L-amino acid transmembrane transporter activity | 9.46e-06 | 41 | 65 | 4 | GO:0015175 | |
| GeneOntologyMolecularFunction | monocarboxylate:sodium symporter activity | 1.46e-05 | 15 | 65 | 3 | GO:0140161 | |
| GeneOntologyMolecularFunction | sodium ion transmembrane transporter activity | 1.96e-05 | 171 | 65 | 6 | GO:0015081 | |
| GeneOntologyMolecularFunction | intracellularly gated calcium channel activity | 2.59e-05 | 18 | 65 | 3 | GO:0015278 | |
| GeneOntologyMolecularFunction | secondary active monocarboxylate transmembrane transporter activity | 3.07e-05 | 19 | 65 | 3 | GO:0015355 | |
| GeneOntologyMolecularFunction | solute:monoatomic cation symporter activity | 4.29e-05 | 119 | 65 | 5 | GO:0015294 | |
| GeneOntologyMolecularFunction | amino acid:sodium symporter activity | 5.57e-05 | 23 | 65 | 3 | GO:0005283 | |
| GeneOntologyMolecularFunction | odorant binding | 5.85e-05 | 127 | 65 | 5 | GO:0005549 | |
| GeneOntologyMolecularFunction | amino acid:monoatomic cation symporter activity | 1.13e-04 | 29 | 65 | 3 | GO:0005416 | |
| GeneOntologyMolecularFunction | ligand-gated calcium channel activity | 1.39e-04 | 31 | 65 | 3 | GO:0099604 | |
| GeneOntologyMolecularFunction | bicarbonate transmembrane transporter activity | 1.53e-04 | 32 | 65 | 3 | GO:0015106 | |
| GeneOntologyMolecularFunction | lactate transmembrane transporter activity | 1.55e-04 | 6 | 65 | 2 | GO:0015129 | |
| GeneOntologyMolecularFunction | gap junction hemi-channel activity | 2.17e-04 | 7 | 65 | 2 | GO:0055077 | |
| GeneOntologyMolecularFunction | amino acid transmembrane transporter activity | 3.82e-04 | 105 | 65 | 4 | GO:0015171 | |
| GeneOntologyMolecularFunction | carboxylic acid transmembrane transporter activity | 5.69e-04 | 207 | 65 | 5 | GO:0046943 | |
| GeneOntologyMolecularFunction | organic acid transmembrane transporter activity | 5.81e-04 | 208 | 65 | 5 | GO:0005342 | |
| GeneOntologyMolecularFunction | calcium:monoatomic cation antiporter activity | 7.95e-04 | 13 | 65 | 2 | GO:0015368 | |
| GeneOntologyMolecularFunction | phospholipid scramblase activity | 2.53e-03 | 23 | 65 | 2 | GO:0017128 | |
| GeneOntologyMolecularFunction | gap junction channel activity | 2.98e-03 | 25 | 65 | 2 | GO:0005243 | |
| GeneOntologyMolecularFunction | monocarboxylic acid transmembrane transporter activity | 3.16e-03 | 90 | 65 | 3 | GO:0008028 | |
| GeneOntologyMolecularFunction | calcium-activated cation channel activity | 3.47e-03 | 27 | 65 | 2 | GO:0005227 | |
| GeneOntologyMolecularFunction | lipid transporter activity | 3.82e-03 | 196 | 65 | 4 | GO:0005319 | |
| GeneOntologyMolecularFunction | monoatomic ion-gated channel activity | 4.57e-03 | 31 | 65 | 2 | GO:0022839 | |
| GeneOntologyMolecularFunction | P-type transmembrane transporter activity | 6.12e-03 | 36 | 65 | 2 | GO:0140358 | |
| GeneOntologyMolecularFunction | P-type ion transporter activity | 6.12e-03 | 36 | 65 | 2 | GO:0015662 | |
| GeneOntologyMolecularFunction | wide pore channel activity | 6.46e-03 | 37 | 65 | 2 | GO:0022829 | |
| GeneOntologyMolecularFunction | calmodulin binding | 6.71e-03 | 230 | 65 | 4 | GO:0005516 | |
| GeneOntologyMolecularFunction | metal cation:monoatomic cation antiporter activity | 8.65e-03 | 43 | 65 | 2 | GO:0140828 | |
| GeneOntologyMolecularFunction | transition metal ion transmembrane transporter activity | 9.04e-03 | 44 | 65 | 2 | GO:0046915 | |
| GeneOntologyMolecularFunction | intramembrane lipid transporter activity | 1.20e-02 | 51 | 65 | 2 | GO:0140303 | |
| GeneOntologyBiologicalProcess | monoatomic ion transport | SLC6A6 BEST1 DRD3 ATP7B ZMPSTE24 SLC24A4 BEST2 BEST4 PKD1L1 SLC6A20 SLC6A19 PKD1 KCNMB1 BEST3 ATP13A5 PANX1 NIPA1 ANO10 SLC5A12 SLC5A8 LCK HEPHL1 SLC1A3 SLC30A10 ANO3 PANX3 RYR1 RYR2 RYR3 KCNH3 OPRK1 | 9.13e-20 | 1374 | 65 | 31 | GO:0006811 |
| GeneOntologyBiologicalProcess | inorganic ion transmembrane transport | SLC6A6 BEST1 DRD3 ATP7B SLC24A4 BEST2 BEST4 PKD1L1 SLC6A20 SLC6A19 PKD1 KCNMB1 BEST3 PANX1 NIPA1 ANO10 SLC5A8 LCK SLC1A3 SLC30A10 ANO3 PANX3 RYR1 RYR2 RYR3 KCNH3 OPRK1 | 8.76e-19 | 1017 | 65 | 27 | GO:0098660 |
| GeneOntologyBiologicalProcess | monoatomic cation transport | SLC6A6 BEST1 DRD3 ATP7B ZMPSTE24 SLC24A4 BEST2 PKD1L1 SLC6A20 SLC6A19 PKD1 KCNMB1 ATP13A5 PANX1 NIPA1 ANO10 SLC5A12 SLC5A8 LCK HEPHL1 SLC1A3 SLC30A10 PANX3 RYR1 RYR2 RYR3 KCNH3 OPRK1 | 1.80e-18 | 1157 | 65 | 28 | GO:0006812 |
| GeneOntologyBiologicalProcess | monoatomic ion transmembrane transport | SLC6A6 BEST1 DRD3 ATP7B SLC24A4 BEST2 BEST4 PKD1L1 SLC6A20 SLC6A19 PKD1 KCNMB1 BEST3 ATP13A5 PANX1 NIPA1 ANO10 LCK SLC1A3 SLC30A10 ANO3 PANX3 RYR1 RYR2 RYR3 KCNH3 OPRK1 | 9.02e-18 | 1115 | 65 | 27 | GO:0034220 |
| GeneOntologyBiologicalProcess | metal ion transport | SLC6A6 BEST1 DRD3 ATP7B ZMPSTE24 SLC24A4 PKD1L1 SLC6A20 SLC6A19 PKD1 KCNMB1 PANX1 NIPA1 SLC5A12 SLC5A8 LCK HEPHL1 SLC1A3 SLC30A10 PANX3 RYR1 RYR2 RYR3 KCNH3 OPRK1 | 1.05e-16 | 1000 | 65 | 25 | GO:0030001 |
| GeneOntologyBiologicalProcess | detection of stimulus | OR5P3 BEST1 OR6V1 OR10H5 SLC24A4 OR9K2 OR10H2 OR10H1 PKD1L1 OR2G3 OR6J1 PKD1 KCNMB1 OR52E4 OR4C46 OR1K1 OR5A2 OR5H14 OR2T10 OR6T1 ANO3 RYR2 | 2.01e-16 | 722 | 65 | 22 | GO:0051606 |
| GeneOntologyBiologicalProcess | monoatomic cation transmembrane transport | SLC6A6 DRD3 ATP7B SLC24A4 BEST2 PKD1L1 SLC6A20 SLC6A19 PKD1 KCNMB1 ATP13A5 PANX1 NIPA1 ANO10 LCK SLC1A3 SLC30A10 PANX3 RYR1 RYR2 RYR3 KCNH3 OPRK1 | 4.16e-15 | 942 | 65 | 23 | GO:0098655 |
| GeneOntologyBiologicalProcess | detection of chemical stimulus | OR5P3 OR6V1 OR10H5 SLC24A4 OR9K2 OR10H2 OR10H1 OR2G3 OR6J1 KCNMB1 OR52E4 OR4C46 OR1K1 OR5A2 OR5H14 OR2T10 OR6T1 RYR2 | 2.40e-14 | 524 | 65 | 18 | GO:0009593 |
| GeneOntologyBiologicalProcess | sensory perception of smell | OR5P3 OR6V1 OR10H5 SLC24A4 OR9K2 OR10H2 OR10H1 BEST2 OR2G3 OR6J1 OR52E4 OR4C46 OR1K1 OR5A2 OR5H14 OR2T10 OR6T1 | 5.19e-14 | 465 | 65 | 17 | GO:0007608 |
| GeneOntologyBiologicalProcess | detection of chemical stimulus involved in sensory perception of smell | OR5P3 OR6V1 OR10H5 SLC24A4 OR9K2 OR10H2 OR10H1 OR2G3 OR6J1 OR52E4 OR4C46 OR1K1 OR5A2 OR5H14 OR2T10 OR6T1 | 2.64e-13 | 432 | 65 | 16 | GO:0050911 |
| GeneOntologyBiologicalProcess | sensory perception of chemical stimulus | OR5P3 OR6V1 OR10H5 SLC24A4 OR9K2 OR10H2 OR10H1 BEST2 OR2G3 OR6J1 OR52E4 OR4C46 OR1K1 OR5A2 OR5H14 OR2T10 OR6T1 | 7.14e-13 | 547 | 65 | 17 | GO:0007606 |
| GeneOntologyBiologicalProcess | detection of chemical stimulus involved in sensory perception | OR5P3 OR6V1 OR10H5 SLC24A4 OR9K2 OR10H2 OR10H1 OR2G3 OR6J1 OR52E4 OR4C46 OR1K1 OR5A2 OR5H14 OR2T10 OR6T1 | 1.54e-12 | 485 | 65 | 16 | GO:0050907 |
| GeneOntologyBiologicalProcess | detection of stimulus involved in sensory perception | OR5P3 BEST1 OR6V1 OR10H5 SLC24A4 OR9K2 OR10H2 OR10H1 OR2G3 OR6J1 OR52E4 OR4C46 OR1K1 OR5A2 OR5H14 OR2T10 OR6T1 | 1.92e-12 | 582 | 65 | 17 | GO:0050906 |
| GeneOntologyBiologicalProcess | inorganic cation transmembrane transport | SLC6A6 DRD3 ATP7B SLC24A4 PKD1L1 SLC6A20 SLC6A19 PKD1 KCNMB1 PANX1 NIPA1 LCK SLC1A3 SLC30A10 PANX3 RYR1 RYR2 RYR3 KCNH3 OPRK1 | 3.48e-12 | 922 | 65 | 20 | GO:0098662 |
| GeneOntologyBiologicalProcess | sensory perception | OR5P3 BEST1 OR6V1 OR10H5 SLC24A4 OR9K2 OR10H2 OR10H1 BEST2 OR2G3 OR6J1 OR52E4 OR4C46 OR1K1 OR5A2 OR5H14 OR2T10 OR6T1 SLC1A3 OPRK1 | 5.27e-11 | 1072 | 65 | 20 | GO:0007600 |
| GeneOntologyBiologicalProcess | G protein-coupled receptor signaling pathway | OR5P3 OR6V1 OR10H5 DRD3 SLC24A4 OR9K2 OR10H2 OR10H1 OR2G3 OR6J1 GPR82 OR52E4 OR4C46 OR1K1 OR5A2 OR5H14 OR2T10 OR6T1 GPR176 OPRK1 | 5.25e-09 | 1395 | 65 | 20 | GO:0007186 |
| GeneOntologyBiologicalProcess | monoatomic anion transport | 5.83e-09 | 183 | 65 | 9 | GO:0006820 | |
| GeneOntologyBiologicalProcess | chloride transport | 6.62e-09 | 128 | 65 | 8 | GO:0006821 | |
| GeneOntologyBiologicalProcess | inorganic anion transmembrane transport | 9.50e-09 | 134 | 65 | 8 | GO:0098661 | |
| GeneOntologyBiologicalProcess | monoatomic anion transmembrane transport | 2.69e-08 | 153 | 65 | 8 | GO:0098656 | |
| GeneOntologyBiologicalProcess | calcium ion transport | BEST1 DRD3 ZMPSTE24 SLC24A4 PKD1L1 PKD1 PANX1 LCK PANX3 RYR1 RYR2 RYR3 | 5.50e-08 | 509 | 65 | 12 | GO:0006816 |
| GeneOntologyBiologicalProcess | chloride transmembrane transport | 6.19e-08 | 112 | 65 | 7 | GO:1902476 | |
| GeneOntologyBiologicalProcess | inorganic anion transport | 9.51e-08 | 180 | 65 | 8 | GO:0015698 | |
| GeneOntologyBiologicalProcess | calcium ion transmembrane transport | 3.87e-07 | 392 | 65 | 10 | GO:0070588 | |
| GeneOntologyBiologicalProcess | response to alkaloid | 2.71e-06 | 125 | 65 | 6 | GO:0043279 | |
| GeneOntologyBiologicalProcess | intracellular monoatomic cation homeostasis | DRD3 ATP7B SLC24A4 ATP13A5 LCK HEPHL1 SLC1A3 SLC30A10 RYR1 RYR2 RYR3 | 2.95e-06 | 611 | 65 | 11 | GO:0030003 |
| GeneOntologyBiologicalProcess | inorganic ion homeostasis | DRD3 ATP7B SLC24A4 ATP13A5 LCK HEPHL1 SLC1A3 SLC30A10 RYR1 RYR2 RYR3 | 3.50e-06 | 622 | 65 | 11 | GO:0098771 |
| GeneOntologyBiologicalProcess | intracellular monoatomic ion homeostasis | DRD3 ATP7B SLC24A4 ATP13A5 LCK HEPHL1 SLC1A3 SLC30A10 RYR1 RYR2 RYR3 | 3.50e-06 | 622 | 65 | 11 | GO:0006873 |
| GeneOntologyBiologicalProcess | organic anion transport | SLC6A6 BEST1 DRD3 BEST2 BEST4 SLC6A20 PANX1 SLC5A12 SLC5A8 SLC1A3 | 4.51e-06 | 515 | 65 | 10 | GO:0015711 |
| GeneOntologyBiologicalProcess | cellular response to caffeine | 4.84e-06 | 11 | 65 | 3 | GO:0071313 | |
| GeneOntologyBiologicalProcess | cellular response to alkaloid | 7.54e-06 | 40 | 65 | 4 | GO:0071312 | |
| GeneOntologyBiologicalProcess | cellular response to purine-containing compound | 1.06e-05 | 14 | 65 | 3 | GO:0071415 | |
| GeneOntologyBiologicalProcess | sarcoplasmic reticulum calcium ion transport | 1.11e-05 | 44 | 65 | 4 | GO:0070296 | |
| GeneOntologyBiologicalProcess | monoatomic cation homeostasis | DRD3 ATP7B SLC24A4 ATP13A5 LCK HEPHL1 SLC1A3 SLC30A10 RYR1 RYR2 RYR3 | 1.15e-05 | 705 | 65 | 11 | GO:0055080 |
| GeneOntologyBiologicalProcess | response to mechanical stimulus | 1.25e-05 | 247 | 65 | 7 | GO:0009612 | |
| GeneOntologyBiologicalProcess | monoatomic ion homeostasis | DRD3 ATP7B SLC24A4 ATP13A5 LCK HEPHL1 SLC1A3 SLC30A10 RYR1 RYR2 RYR3 | 1.34e-05 | 717 | 65 | 11 | GO:0050801 |
| GeneOntologyBiologicalProcess | intracellular chemical homeostasis | DRD3 ATP7B SLC24A4 ATP13A5 LCK HEPHL1 SLC1A3 SLC30A10 RYR1 RYR2 RYR3 OPRK1 | 1.44e-05 | 866 | 65 | 12 | GO:0055082 |
| GeneOntologyBiologicalProcess | response to abiotic stimulus | RHBDD1 BEST1 DRD3 ZMPSTE24 SLC24A4 PKD1L1 KIAA0319L PKD1 KCNMB1 LCK SLC1A3 ANO3 RYR1 RYR2 TP53BP1 | 1.63e-05 | 1361 | 65 | 15 | GO:0009628 |
| GeneOntologyBiologicalProcess | intracellular calcium ion homeostasis | 1.66e-05 | 359 | 65 | 8 | GO:0006874 | |
| GeneOntologyBiologicalProcess | calcium ion homeostasis | 2.94e-05 | 389 | 65 | 8 | GO:0055074 | |
| GeneOntologyBiologicalProcess | response to caffeine | 3.81e-05 | 21 | 65 | 3 | GO:0031000 | |
| GeneOntologyBiologicalProcess | neutral amino acid transport | 3.84e-05 | 60 | 65 | 4 | GO:0015804 | |
| GeneOntologyBiologicalProcess | cellular homeostasis | DRD3 ATP7B SLC24A4 ATP13A5 LCK HEPHL1 SLC1A3 SLC30A10 RYR1 RYR2 RYR3 OPRK1 | 4.90e-05 | 981 | 65 | 12 | GO:0019725 |
| GeneOntologyBiologicalProcess | negative regulation of cytosolic calcium ion concentration | 6.54e-05 | 25 | 65 | 3 | GO:0051481 | |
| GeneOntologyBiologicalProcess | chemical homeostasis | DRD3 ATP7B SLC24A4 ATP13A5 APOB LCK HEPHL1 SLC1A3 SLC30A10 RYR1 RYR2 RYR3 OPRK1 | 1.19e-04 | 1249 | 65 | 13 | GO:0048878 |
| GeneOntologyBiologicalProcess | sequestering of calcium ion | 1.21e-04 | 153 | 65 | 5 | GO:0051208 | |
| GeneOntologyBiologicalProcess | organic acid transmembrane transport | 1.83e-04 | 167 | 65 | 5 | GO:1903825 | |
| GeneOntologyBiologicalProcess | calcium-mediated signaling | 1.90e-04 | 266 | 65 | 6 | GO:0019722 | |
| GeneOntologyBiologicalProcess | potassium ion transport | 2.14e-04 | 272 | 65 | 6 | GO:0006813 | |
| GeneOntologyBiologicalProcess | release of sequestered calcium ion into cytosol by sarcoplasmic reticulum | 2.15e-04 | 37 | 65 | 3 | GO:0014808 | |
| GeneOntologyBiologicalProcess | detection of external stimulus | 2.15e-04 | 173 | 65 | 5 | GO:0009581 | |
| GeneOntologyBiologicalProcess | detection of abiotic stimulus | 2.27e-04 | 175 | 65 | 5 | GO:0009582 | |
| GeneOntologyBiologicalProcess | sodium ion transport | 2.27e-04 | 275 | 65 | 6 | GO:0006814 | |
| GeneOntologyBiologicalProcess | bicarbonate transport | 2.33e-04 | 38 | 65 | 3 | GO:0015701 | |
| GeneOntologyBiologicalProcess | release of sequestered calcium ion into cytosol by endoplasmic reticulum | 2.52e-04 | 39 | 65 | 3 | GO:1903514 | |
| GeneOntologyBiologicalProcess | response to ATP | 2.72e-04 | 40 | 65 | 3 | GO:0033198 | |
| GeneOntologyBiologicalProcess | carboxylic acid transport | 3.01e-04 | 410 | 65 | 7 | GO:0046942 | |
| GeneOntologyBiologicalProcess | organic acid transport | 3.10e-04 | 412 | 65 | 7 | GO:0015849 | |
| GeneOntologyBiologicalProcess | response to metal ion | 3.23e-04 | 415 | 65 | 7 | GO:0010038 | |
| GeneOntologyBiologicalProcess | lactate transport | 3.47e-04 | 9 | 65 | 2 | GO:0015727 | |
| GeneOntologyBiologicalProcess | lactate transmembrane transport | 3.47e-04 | 9 | 65 | 2 | GO:0035873 | |
| GeneOntologyBiologicalProcess | amino acid transport | 3.74e-04 | 195 | 65 | 5 | GO:0006865 | |
| GeneOntologyBiologicalProcess | transition metal ion transport | 4.47e-04 | 113 | 65 | 4 | GO:0000041 | |
| GeneOntologyBiologicalProcess | amino acid transmembrane transport | 5.61e-04 | 120 | 65 | 4 | GO:0003333 | |
| GeneOntologyBiologicalProcess | calcium ion transmembrane import into cytosol | 6.09e-04 | 217 | 65 | 5 | GO:0097553 | |
| GeneOntologyBiologicalProcess | manganese ion transmembrane transport | 6.32e-04 | 12 | 65 | 2 | GO:0071421 | |
| GeneOntologyBiologicalProcess | detection of calcium ion | 7.46e-04 | 13 | 65 | 2 | GO:0005513 | |
| GeneOntologyBiologicalProcess | amino acid import across plasma membrane | 8.14e-04 | 58 | 65 | 3 | GO:0089718 | |
| GeneOntologyBiologicalProcess | potassium ion transmembrane transport | 8.23e-04 | 232 | 65 | 5 | GO:0071805 | |
| GeneOntologyBiologicalProcess | manganese ion transport | 8.68e-04 | 14 | 65 | 2 | GO:0006828 | |
| GeneOntologyBiologicalProcess | organic hydroxy compound transport | 9.15e-04 | 358 | 65 | 6 | GO:0015850 | |
| GeneOntologyBiologicalProcess | response to radiation | 1.01e-03 | 503 | 65 | 7 | GO:0009314 | |
| GeneOntologyBiologicalProcess | regulation of eating behavior | 1.14e-03 | 16 | 65 | 2 | GO:1903998 | |
| GeneOntologyBiologicalProcess | release of sequestered calcium ion into cytosol | 1.17e-03 | 146 | 65 | 4 | GO:0051209 | |
| GeneOntologyBiologicalProcess | negative regulation of sequestering of calcium ion | 1.20e-03 | 147 | 65 | 4 | GO:0051283 | |
| GeneOntologyBiologicalProcess | regulation of sequestering of calcium ion | 1.26e-03 | 149 | 65 | 4 | GO:0051282 | |
| GeneOntologyBiologicalProcess | maintenance of location in cell | 1.34e-03 | 259 | 65 | 5 | GO:0051651 | |
| GeneOntologyBiologicalProcess | response to cocaine | 1.47e-03 | 71 | 65 | 3 | GO:0042220 | |
| GeneOntologyBiologicalProcess | maintenance of location | 1.53e-03 | 396 | 65 | 6 | GO:0051235 | |
| GeneOntologyBiologicalProcess | response to calcium ion | 1.67e-03 | 161 | 65 | 4 | GO:0051592 | |
| GeneOntologyBiologicalProcess | detection of mechanical stimulus | 1.72e-03 | 75 | 65 | 3 | GO:0050982 | |
| GeneOntologyBiologicalProcess | carboxylic acid transmembrane transport | 1.75e-03 | 163 | 65 | 4 | GO:1905039 | |
| GeneOntologyBiologicalProcess | copper ion transport | 1.79e-03 | 20 | 65 | 2 | GO:0006825 | |
| GeneOntologyBiologicalProcess | intracellular copper ion homeostasis | 1.79e-03 | 20 | 65 | 2 | GO:0006878 | |
| GeneOntologyBiologicalProcess | response to purine-containing compound | 1.87e-03 | 166 | 65 | 4 | GO:0014074 | |
| GeneOntologyBiologicalProcess | response to nitrogen compound | RHBDD1 DRD3 SLC24A4 UMODL1 PANX1 SLC1A3 SLC30A10 RYR1 RYR2 RYR3 OPRK1 | 1.94e-03 | 1272 | 65 | 11 | GO:1901698 |
| GeneOntologyBiologicalProcess | cellular response to ATP | 1.98e-03 | 21 | 65 | 2 | GO:0071318 | |
| GeneOntologyBiologicalProcess | catecholamine secretion | 1.99e-03 | 79 | 65 | 3 | GO:0050432 | |
| GeneOntologyBiologicalProcess | circulatory system process | 2.07e-03 | 733 | 65 | 8 | GO:0003013 | |
| GeneOntologyBiologicalProcess | copper ion homeostasis | 2.37e-03 | 23 | 65 | 2 | GO:0055070 | |
| GeneOntologyBiologicalProcess | acidic amino acid transport | 2.37e-03 | 84 | 65 | 3 | GO:0015800 | |
| GeneOntologyBiologicalProcess | protein complex oligomerization | 2.41e-03 | 296 | 65 | 5 | GO:0051259 | |
| GeneOntologyBiologicalProcess | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway | 2.54e-03 | 86 | 65 | 3 | GO:0007193 | |
| GeneOntologyBiologicalProcess | behavioral response to cocaine | 2.58e-03 | 24 | 65 | 2 | GO:0048148 | |
| GeneOntologyBiologicalProcess | transport across blood-brain barrier | 2.62e-03 | 87 | 65 | 3 | GO:0150104 | |
| GeneOntologyBiologicalProcess | vascular transport | 2.71e-03 | 88 | 65 | 3 | GO:0010232 | |
| GeneOntologyBiologicalProcess | response to magnesium ion | 2.80e-03 | 25 | 65 | 2 | GO:0032026 | |
| GeneOntologyBiologicalProcess | export across plasma membrane | 2.98e-03 | 91 | 65 | 3 | GO:0140115 | |
| GeneOntologyCellularComponent | monoatomic ion channel complex | BEST1 BEST2 BEST4 PKD1L1 PKD1 KCNMB1 BEST3 RYR1 RYR2 RYR3 KCNH3 | 2.18e-08 | 378 | 65 | 11 | GO:0034702 |
| GeneOntologyCellularComponent | transmembrane transporter complex | BEST1 BEST2 BEST4 PKD1L1 PKD1 KCNMB1 BEST3 RYR1 RYR2 RYR3 KCNH3 | 5.71e-07 | 523 | 65 | 11 | GO:1902495 |
| GeneOntologyCellularComponent | transporter complex | BEST1 BEST2 BEST4 PKD1L1 PKD1 KCNMB1 BEST3 RYR1 RYR2 RYR3 KCNH3 | 9.37e-07 | 550 | 65 | 11 | GO:1990351 |
| GeneOntologyCellularComponent | calcium channel complex | 3.17e-06 | 73 | 65 | 5 | GO:0034704 | |
| GeneOntologyCellularComponent | smooth endoplasmic reticulum | 1.26e-05 | 46 | 65 | 4 | GO:0005790 | |
| GeneOntologyCellularComponent | chloride channel complex | 2.97e-05 | 57 | 65 | 4 | GO:0034707 | |
| GeneOntologyCellularComponent | cation channel complex | 8.99e-05 | 235 | 65 | 6 | GO:0034703 | |
| GeneOntologyCellularComponent | brush border membrane | 1.30e-04 | 83 | 65 | 4 | GO:0031526 | |
| GeneOntologyCellularComponent | sarcoplasmic reticulum | 1.63e-04 | 88 | 65 | 4 | GO:0016529 | |
| GeneOntologyCellularComponent | membrane protein complex | SLC6A6 OSTC BEST1 BEST2 BEST4 PKD1L1 PKD1 KCNMB1 BEST3 SLC1A3 RYR1 RYR2 RYR3 KCNH3 | 1.69e-04 | 1498 | 65 | 14 | GO:0098796 |
| GeneOntologyCellularComponent | sarcolemma | 3.12e-04 | 190 | 65 | 5 | GO:0042383 | |
| GeneOntologyCellularComponent | junctional membrane complex | 3.38e-04 | 9 | 65 | 2 | GO:0030314 | |
| GeneOntologyCellularComponent | sarcoplasmic reticulum membrane | 3.71e-04 | 45 | 65 | 3 | GO:0033017 | |
| GeneOntologyCellularComponent | cell projection membrane | 3.75e-04 | 431 | 65 | 7 | GO:0031253 | |
| GeneOntologyCellularComponent | junctional sarcoplasmic reticulum membrane | 4.22e-04 | 10 | 65 | 2 | GO:0014701 | |
| GeneOntologyCellularComponent | sarcoplasm | 4.40e-04 | 114 | 65 | 4 | GO:0016528 | |
| GeneOntologyCellularComponent | basolateral plasma membrane | 4.75e-04 | 320 | 65 | 6 | GO:0016323 | |
| GeneOntologyCellularComponent | apical part of cell | 4.81e-04 | 592 | 65 | 8 | GO:0045177 | |
| GeneOntologyCellularComponent | endoplasmic reticulum membrane | OSTC RHBDD1 ZMPSTE24 PEMT PGAP2 PANX1 APOB PANX3 RYR1 RYR2 RYR3 RHEB | 5.66e-04 | 1293 | 65 | 12 | GO:0005789 |
| GeneOntologyCellularComponent | endoplasmic reticulum subcompartment | OSTC RHBDD1 ZMPSTE24 PEMT PGAP2 PANX1 APOB PANX3 RYR1 RYR2 RYR3 RHEB | 5.90e-04 | 1299 | 65 | 12 | GO:0098827 |
| GeneOntologyCellularComponent | nuclear outer membrane-endoplasmic reticulum membrane network | OSTC RHBDD1 ZMPSTE24 PEMT PGAP2 PANX1 APOB PANX3 RYR1 RYR2 RYR3 RHEB | 7.12e-04 | 1327 | 65 | 12 | GO:0042175 |
| GeneOntologyCellularComponent | basal plasma membrane | 8.05e-04 | 354 | 65 | 6 | GO:0009925 | |
| GeneOntologyCellularComponent | basal part of cell | 1.13e-03 | 378 | 65 | 6 | GO:0045178 | |
| GeneOntologyCellularComponent | brush border | 1.29e-03 | 152 | 65 | 4 | GO:0005903 | |
| GeneOntologyCellularComponent | apical plasma membrane | 4.01e-03 | 487 | 65 | 6 | GO:0016324 | |
| GeneOntologyCellularComponent | cluster of actin-based cell projections | 5.13e-03 | 223 | 65 | 4 | GO:0098862 | |
| GeneOntologyCellularComponent | gap junction | 5.91e-03 | 37 | 65 | 2 | GO:0005921 | |
| GeneOntologyCellularComponent | Golgi membrane | 6.93e-03 | 721 | 65 | 7 | GO:0000139 | |
| MousePheno | increased circulating copper level | 9.24e-06 | 2 | 43 | 2 | MP:0006350 | |
| MousePheno | abnormal behavioral response to xenobiotic | 3.92e-05 | 309 | 43 | 7 | MP:0009745 | |
| MousePheno | abnormal circulating copper level | 5.52e-05 | 4 | 43 | 2 | MP:0006348 | |
| Domain | 7tm_1 | OR5P3 OR6V1 OR10H5 DRD3 OR9K2 OR10H2 OR10H1 OR2G3 OR6J1 GPR82 OR52E4 OR4C46 OR1K1 OR5A2 OR5H14 OR2T10 OR6T1 GPR176 OPRK1 | 8.51e-13 | 677 | 65 | 19 | PF00001 |
| Domain | G_PROTEIN_RECEP_F1_1 | OR5P3 OR6V1 OR10H5 DRD3 OR9K2 OR10H2 OR10H1 OR2G3 OR6J1 GPR82 OR52E4 OR4C46 OR1K1 OR5A2 OR5H14 OR2T10 OR6T1 GPR176 OPRK1 | 1.05e-12 | 685 | 65 | 19 | PS00237 |
| Domain | G_PROTEIN_RECEP_F1_2 | OR5P3 OR6V1 OR10H5 DRD3 OR9K2 OR10H2 OR10H1 OR2G3 OR6J1 GPR82 OR52E4 OR4C46 OR1K1 OR5A2 OR5H14 OR2T10 OR6T1 GPR176 OPRK1 | 1.22e-12 | 691 | 65 | 19 | PS50262 |
| Domain | GPCR_Rhodpsn | OR5P3 OR6V1 OR10H5 DRD3 OR9K2 OR10H2 OR10H1 OR2G3 OR6J1 GPR82 OR52E4 OR4C46 OR1K1 OR5A2 OR5H14 OR2T10 OR6T1 GPR176 OPRK1 | 1.25e-12 | 692 | 65 | 19 | IPR000276 |
| Domain | Olfact_rcpt | OR5P3 OR6V1 OR10H5 OR9K2 OR10H2 OR10H1 OR2G3 OR6J1 OR52E4 OR4C46 OR1K1 OR5A2 OR5H14 OR2T10 OR6T1 | 4.29e-12 | 393 | 65 | 15 | IPR000725 |
| Domain | GPCR_Rhodpsn_7TM | OR5P3 OR6V1 OR10H5 DRD3 OR9K2 OR10H2 OR10H1 OR2G3 GPR82 OR52E4 OR4C46 OR1K1 OR5A2 OR5H14 OR2T10 OR6T1 GPR176 OPRK1 | 7.95e-12 | 670 | 65 | 18 | IPR017452 |
| Domain | Bestrophin/UPF0187 | 1.34e-10 | 4 | 65 | 4 | IPR021134 | |
| Domain | Bestrophin | 1.34e-10 | 4 | 65 | 4 | IPR000615 | |
| Domain | Bestrophin | 1.34e-10 | 4 | 65 | 4 | PF01062 | |
| Domain | RyR | 4.02e-08 | 3 | 65 | 3 | PF02026 | |
| Domain | Ryanodine_rcpt | 4.02e-08 | 3 | 65 | 3 | IPR003032 | |
| Domain | RR_TM4-6 | 4.02e-08 | 3 | 65 | 3 | PF06459 | |
| Domain | Ryanrecept_TM4-6 | 4.02e-08 | 3 | 65 | 3 | IPR009460 | |
| Domain | Ryan_recept | 4.02e-08 | 3 | 65 | 3 | IPR013333 | |
| Domain | REJ | 7.99e-07 | 6 | 65 | 3 | PF02010 | |
| Domain | RIH_assoc | 7.99e-07 | 6 | 65 | 3 | PF08454 | |
| Domain | RIH_assoc-dom | 7.99e-07 | 6 | 65 | 3 | IPR013662 | |
| Domain | RYDR_ITPR | 7.99e-07 | 6 | 65 | 3 | PF01365 | |
| Domain | RIH_dom | 7.99e-07 | 6 | 65 | 3 | IPR000699 | |
| Domain | Ins145_P3_rcpt | 7.99e-07 | 6 | 65 | 3 | IPR014821 | |
| Domain | Ryanodine_recept-rel | 7.99e-07 | 6 | 65 | 3 | IPR015925 | |
| Domain | PKD/REJ-like | 7.99e-07 | 6 | 65 | 3 | IPR002859 | |
| Domain | Ins145_P3_rec | 7.99e-07 | 6 | 65 | 3 | PF08709 | |
| Domain | - | 7.99e-07 | 6 | 65 | 3 | 1.25.10.30 | |
| Domain | PKD | 3.33e-06 | 9 | 65 | 3 | SM00089 | |
| Domain | PKD/Chitinase_dom | 3.33e-06 | 9 | 65 | 3 | IPR022409 | |
| Domain | MIR | 4.74e-06 | 10 | 65 | 3 | PS50919 | |
| Domain | MIR | 4.74e-06 | 10 | 65 | 3 | PF02815 | |
| Domain | MIR | 4.74e-06 | 10 | 65 | 3 | SM00472 | |
| Domain | MIR_motif | 4.74e-06 | 10 | 65 | 3 | IPR016093 | |
| Domain | PKD | 6.51e-06 | 11 | 65 | 3 | PS50093 | |
| Domain | PKD_dom | 6.51e-06 | 11 | 65 | 3 | IPR000601 | |
| Domain | - | 6.51e-06 | 11 | 65 | 3 | 2.60.40.670 | |
| Domain | Innexin | 3.57e-05 | 3 | 65 | 2 | PF00876 | |
| Domain | Innexin | 3.57e-05 | 3 | 65 | 2 | IPR000990 | |
| Domain | PANNEXIN | 3.57e-05 | 3 | 65 | 2 | PS51013 | |
| Domain | NA_NEUROTRAN_SYMP_3 | 3.75e-05 | 19 | 65 | 3 | PS50267 | |
| Domain | SNF | 3.75e-05 | 19 | 65 | 3 | PF00209 | |
| Domain | Na/ntran_symport | 3.75e-05 | 19 | 65 | 3 | IPR000175 | |
| Domain | NA_NEUROTRAN_SYMP_1 | 3.75e-05 | 19 | 65 | 3 | PS00610 | |
| Domain | REJ | 7.12e-05 | 4 | 65 | 2 | PS51111 | |
| Domain | REJ_dom | 7.12e-05 | 4 | 65 | 2 | IPR014010 | |
| Domain | Na/ntran_symport_orphan | 1.18e-04 | 5 | 65 | 2 | IPR002438 | |
| Domain | Bax_inhibitor_1-related | 1.77e-04 | 6 | 65 | 2 | IPR006214 | |
| Domain | Frag1/DRAM/Sfk1 | 1.77e-04 | 6 | 65 | 2 | IPR019402 | |
| Domain | Frag1 | 1.77e-04 | 6 | 65 | 2 | PF10277 | |
| Domain | PKD | 2.48e-04 | 7 | 65 | 2 | PF00801 | |
| Domain | Anoctamin | 5.27e-04 | 10 | 65 | 2 | PF04547 | |
| Domain | Anoctamin | 5.27e-04 | 10 | 65 | 2 | IPR007632 | |
| Domain | NA_SOLUT_SYMP_1 | 6.43e-04 | 11 | 65 | 2 | PS00456 | |
| Domain | PKD1_2_channel | 6.43e-04 | 11 | 65 | 2 | IPR013122 | |
| Domain | PKD_channel | 6.43e-04 | 11 | 65 | 2 | PF08016 | |
| Domain | Ion_trans_dom | 6.69e-04 | 114 | 65 | 4 | IPR005821 | |
| Domain | Ion_trans | 6.69e-04 | 114 | 65 | 4 | PF00520 | |
| Domain | NA_SOLUT_SYMP_2 | 7.70e-04 | 12 | 65 | 2 | PS00457 | |
| Domain | SSF | 7.70e-04 | 12 | 65 | 2 | PF00474 | |
| Domain | Na/solute_symporter | 7.70e-04 | 12 | 65 | 2 | IPR001734 | |
| Domain | NA_SOLUT_SYMP_3 | 7.70e-04 | 12 | 65 | 2 | PS50283 | |
| Domain | Gal_mutarotase_SF_dom | 1.57e-03 | 17 | 65 | 2 | IPR011013 | |
| Domain | LH2 | 1.76e-03 | 18 | 65 | 2 | SM00308 | |
| Domain | NA_NEUROTRAN_SYMP_2 | 1.76e-03 | 18 | 65 | 2 | PS00754 | |
| Domain | Tetraspanin_CS | 2.40e-03 | 21 | 65 | 2 | IPR018503 | |
| Domain | PLAT | 2.40e-03 | 21 | 65 | 2 | PF01477 | |
| Domain | PLAT | 2.40e-03 | 21 | 65 | 2 | PS50095 | |
| Domain | PLAT/LH2_dom | 2.40e-03 | 21 | 65 | 2 | IPR001024 | |
| Domain | - | 2.40e-03 | 21 | 65 | 2 | 2.60.60.20 | |
| Domain | SPRY | 3.46e-03 | 87 | 65 | 3 | SM00449 | |
| Pathway | REACTOME_TRANSPORT_OF_SMALL_MOLECULES | SLC6A6 BEST1 ATP7B SLC24A4 BEST2 BEST4 SLC6A20 SLC6A19 BEST3 ATP13A5 APOB NIPA1 ANO10 SLC5A12 SLC5A8 SLC1A3 SLC30A10 ANO3 RYR1 RYR2 RYR3 | 3.21e-13 | 736 | 57 | 21 | M27287 |
| Pathway | REACTOME_TRANSPORT_OF_SMALL_MOLECULES | SLC6A6 BEST1 ATP7B SLC24A4 BEST2 SLC6A20 SLC6A19 BEST3 ATP13A5 APOB NIPA1 ANO10 SLC5A12 SLC5A8 SLC1A3 SLC30A10 ANO3 RYR1 RYR2 RYR3 | 8.17e-13 | 681 | 57 | 20 | MM14985 |
| Pathway | REACTOME_OLFACTORY_SIGNALING_PATHWAY | OR5P3 OR6V1 OR10H5 OR9K2 OR10H2 OR10H1 OR2G3 OR6J1 OR52E4 OR4C46 OR1K1 OR5A2 OR5H14 OR2T10 OR6T1 | 6.41e-11 | 417 | 57 | 15 | M4072 |
| Pathway | REACTOME_ION_CHANNEL_TRANSPORT | BEST1 ATP7B BEST2 BEST4 BEST3 ATP13A5 ANO10 ANO3 RYR1 RYR2 RYR3 | 1.43e-10 | 183 | 57 | 11 | M997 |
| Pathway | REACTOME_SENSORY_PERCEPTION | OR5P3 OR6V1 OR10H5 OR9K2 OR10H2 OR10H1 OR2G3 OR6J1 KCNMB1 OR52E4 OR4C46 OR1K1 OR5A2 OR5H14 APOB OR2T10 OR6T1 | 2.78e-10 | 636 | 57 | 17 | M41834 |
| Pathway | REACTOME_STIMULI_SENSING_CHANNELS | 3.63e-10 | 106 | 57 | 9 | M27200 | |
| Pathway | REACTOME_ION_CHANNEL_TRANSPORT | 1.85e-09 | 176 | 57 | 10 | MM15718 | |
| Pathway | KEGG_OLFACTORY_TRANSDUCTION | OR5P3 OR6V1 OR10H5 OR9K2 OR10H2 OR10H1 OR2G3 OR52E4 OR4C46 OR1K1 OR5A2 OR2T10 OR6T1 | 3.59e-09 | 389 | 57 | 13 | M14091 |
| Pathway | REACTOME_STIMULI_SENSING_CHANNELS | 5.53e-09 | 99 | 57 | 8 | MM14910 | |
| Pathway | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | 2.46e-07 | 108 | 57 | 7 | M823 | |
| Pathway | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | 2.62e-07 | 109 | 57 | 7 | MM15074 | |
| Pathway | REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT | SLC6A6 SLC24A4 SLC6A20 SLC6A19 SLC5A12 SLC5A8 SLC1A3 SLC30A10 | 4.75e-06 | 238 | 57 | 8 | MM15076 |
| Pathway | REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT | SLC6A6 SLC24A4 SLC6A20 SLC6A19 SLC5A12 SLC5A8 SLC1A3 SLC30A10 | 6.63e-06 | 249 | 57 | 8 | M5988 |
| Pathway | KEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY | 1.01e-05 | 11 | 57 | 3 | M47958 | |
| Pathway | WP_CELLTYPE_DEPENDENT_SELECTIVITY_OF_CCK2R_SIGNALING | 1.74e-05 | 13 | 57 | 3 | M39589 | |
| Pathway | REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS | 5.80e-05 | 19 | 57 | 3 | M27362 | |
| Pathway | KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 5.80e-05 | 19 | 57 | 3 | M47760 | |
| Pathway | REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS | 5.80e-05 | 19 | 57 | 3 | MM15107 | |
| Pathway | REACTOME_OLFACTORY_SIGNALING_PATHWAY | 1.81e-04 | 70 | 57 | 4 | MM14984 | |
| Pathway | REACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS | 2.48e-04 | 76 | 57 | 4 | MM15072 | |
| Pathway | WP_NRF2_PATHWAY | 2.57e-04 | 141 | 57 | 5 | M39454 | |
| Pathway | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | 2.86e-04 | 32 | 57 | 3 | MM14957 | |
| Pathway | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | 3.14e-04 | 33 | 57 | 3 | M188 | |
| Pathway | REACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS | 3.64e-04 | 84 | 57 | 4 | M27334 | |
| Pathway | WP_AMINO_ACID_TRANSPORT_DEFECTS_IEMS | 5.68e-04 | 9 | 57 | 2 | M48047 | |
| Pathway | REACTOME_SLC_TRANSPORTER_DISORDERS | 6.80e-04 | 99 | 57 | 4 | M27474 | |
| Pathway | REACTOME_SENSORY_PERCEPTION | 1.00e-03 | 190 | 57 | 5 | MM15687 | |
| Pathway | REACTOME_INDUCTION_OF_CELL_CELL_FUSION | 1.22e-03 | 13 | 57 | 2 | M46426 | |
| Pathway | REACTOME_ION_HOMEOSTASIS | 1.34e-03 | 54 | 57 | 3 | M27460 | |
| Pathway | REACTOME_ION_HOMEOSTASIS | 1.34e-03 | 54 | 57 | 3 | MM15202 | |
| Pathway | WP_PROXIMAL_TUBULE_TRANSPORT | 1.57e-03 | 57 | 57 | 3 | M39812 | |
| Pubmed | Three novel human VMD2-like genes are members of the evolutionary highly conserved RFP-TM family. | 1.11e-11 | 4 | 65 | 4 | 12032738 | |
| Pubmed | Bestrophin expression and function in the human pancreatic duct cell line, CFPAC-1. | 1.11e-11 | 4 | 65 | 4 | 19237432 | |
| Pubmed | Structure-function analysis of the bestrophin family of anion channels. | 1.11e-11 | 4 | 65 | 4 | 12907679 | |
| Pubmed | 1.11e-11 | 4 | 65 | 4 | 9700209 | ||
| Pubmed | OR5P3 OR6V1 OR10H5 OR9K2 OR10H2 OR10H1 OR2G3 OR52E4 OR5A2 OR5H14 OR2T10 OR6T1 | 3.39e-10 | 541 | 65 | 12 | 14983052 | |
| Pubmed | 6.23e-09 | 3 | 65 | 3 | 18403125 | ||
| Pubmed | 6.23e-09 | 3 | 65 | 3 | 18400985 | ||
| Pubmed | 6.23e-09 | 3 | 65 | 3 | 18434746 | ||
| Pubmed | SPRY domains in ryanodine receptors (Ca(2+)-release channels). | 6.23e-09 | 3 | 65 | 3 | 9204703 | |
| Pubmed | 6.23e-09 | 3 | 65 | 3 | 7876312 | ||
| Pubmed | 6.23e-09 | 3 | 65 | 3 | 21881589 | ||
| Pubmed | Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors). | 6.23e-09 | 3 | 65 | 3 | 12213830 | |
| Pubmed | Cloning and characterization of the murine Vmd2 RFP-TM gene family. | 6.23e-09 | 3 | 65 | 3 | 15218265 | |
| Pubmed | 6.23e-09 | 3 | 65 | 3 | 9242641 | ||
| Pubmed | 6.23e-09 | 3 | 65 | 3 | 22948152 | ||
| Pubmed | Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain. | 6.23e-09 | 3 | 65 | 3 | 10788707 | |
| Pubmed | 6.23e-09 | 3 | 65 | 3 | 25239916 | ||
| Pubmed | Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor. | 6.23e-09 | 3 | 65 | 3 | 7621815 | |
| Pubmed | 6.23e-09 | 3 | 65 | 3 | 18643873 | ||
| Pubmed | 6.23e-09 | 3 | 65 | 3 | 11159936 | ||
| Pubmed | Molecular identification of the ryanodine receptor pore-forming segment. | 6.23e-09 | 3 | 65 | 3 | 10473538 | |
| Pubmed | 6.23e-09 | 3 | 65 | 3 | 7959768 | ||
| Pubmed | The organization of proteins in the human red blood cell membrane. A review. | 6.23e-09 | 3 | 65 | 3 | 4600883 | |
| Pubmed | 6.23e-09 | 3 | 65 | 3 | 7635066 | ||
| Pubmed | 2.49e-08 | 4 | 65 | 3 | 18206662 | ||
| Pubmed | Ryanodine receptor calcium release channels: lessons from structure-function studies. | 2.49e-08 | 4 | 65 | 3 | 23413940 | |
| Pubmed | 2.49e-08 | 4 | 65 | 3 | 9384575 | ||
| Pubmed | 2.49e-08 | 4 | 65 | 3 | 9607712 | ||
| Pubmed | 2.49e-08 | 4 | 65 | 3 | 23482488 | ||
| Pubmed | 6.21e-08 | 5 | 65 | 3 | 23918386 | ||
| Pubmed | Protein kinase C-epsilon regulates local calcium signaling in airway smooth muscle cells. | 6.21e-08 | 5 | 65 | 3 | 19011160 | |
| Pubmed | 1.24e-07 | 6 | 65 | 3 | 19549818 | ||
| Pubmed | Rectification of muscle and nerve deficits in paralyzed ryanodine receptor type 1 mutant embryos. | 1.24e-07 | 6 | 65 | 3 | 26025922 | |
| Pubmed | 1.24e-07 | 6 | 65 | 3 | 23463619 | ||
| Pubmed | FKBP12.6 and cADPR regulation of Ca2+ release in smooth muscle cells. | 1.24e-07 | 6 | 65 | 3 | 14592808 | |
| Pubmed | 1.24e-07 | 6 | 65 | 3 | 20519450 | ||
| Pubmed | Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging. | 1.24e-07 | 6 | 65 | 3 | 25966694 | |
| Pubmed | 1.24e-07 | 6 | 65 | 3 | 19009018 | ||
| Pubmed | IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1. | 1.24e-07 | 6 | 65 | 3 | 16844763 | |
| Pubmed | 2.17e-07 | 7 | 65 | 3 | 11860456 | ||
| Pubmed | 2.17e-07 | 7 | 65 | 3 | 20962236 | ||
| Pubmed | Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death. | 3.47e-07 | 8 | 65 | 3 | 19033399 | |
| Pubmed | 3.47e-07 | 8 | 65 | 3 | 11784029 | ||
| Pubmed | 1.35e-06 | 12 | 65 | 3 | 19095005 | ||
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 25239622 | ||
| Pubmed | Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease. | 3.44e-06 | 2 | 65 | 2 | 21531043 | |
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 16678258 | ||
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 17925379 | ||
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 12565913 | ||
| Pubmed | Diverse subcellular distribution profiles of pannexin 1 and pannexin 3. | 3.44e-06 | 2 | 65 | 2 | 18649185 | |
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 9489997 | ||
| Pubmed | Bestrophin 1 and 2 are components of the Ca(2+) activated Cl(-) conductance in mouse airways. | 3.44e-06 | 2 | 65 | 2 | 18652850 | |
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 17259277 | ||
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 9192302 | ||
| Pubmed | The block of ryanodine receptors selectively inhibits fetal myoblast differentiation. | 3.44e-06 | 2 | 65 | 2 | 12640042 | |
| Pubmed | Ryanodine receptor oligomeric interaction: identification of a putative binding region. | 3.44e-06 | 2 | 65 | 2 | 14722100 | |
| Pubmed | Structural and functional interactions within ryanodine receptor. | 3.44e-06 | 2 | 65 | 2 | 26009179 | |
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 7556644 | ||
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 16707793 | ||
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 32899693 | ||
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 14592949 | ||
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 8898078 | ||
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 17692818 | ||
| Pubmed | Structures and gating mechanisms of human bestrophin anion channels. | 3.44e-06 | 2 | 65 | 2 | 35789156 | |
| Pubmed | Ryanodine receptors in muscarinic receptor-mediated bronchoconstriction. | 3.44e-06 | 2 | 65 | 2 | 15894801 | |
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 30542613 | ||
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 14550562 | ||
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 29222846 | ||
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 15280431 | ||
| Pubmed | Expression of the ryanodine receptor isoforms in immune cells. | 3.44e-06 | 2 | 65 | 2 | 11673493 | |
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 11673462 | ||
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 9799464 | ||
| Pubmed | A variant of the Ca2+-activated Cl channel Best3 is expressed in mouse exocrine glands. | 3.44e-06 | 2 | 65 | 2 | 18414923 | |
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 9817784 | ||
| Pubmed | Lineage-specific expression of bestrophin-2 and bestrophin-4 in human intestinal epithelial cells. | 3.44e-06 | 2 | 65 | 2 | 24223998 | |
| Pubmed | Inhibition of pannexin-1 does not restore electrolyte balance in precystic Pkd1 knockout mice. | 3.44e-06 | 2 | 65 | 2 | 38561249 | |
| Pubmed | Regulation of Skeletal Muscle Myoblast Differentiation and Proliferation by Pannexins. | 3.44e-06 | 2 | 65 | 2 | 27518505 | |
| Pubmed | Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain. | 3.44e-06 | 2 | 65 | 2 | 25370123 | |
| Pubmed | The vitelliform macular dystrophy protein defines a new family of chloride channels. | 3.44e-06 | 2 | 65 | 2 | 11904445 | |
| Pubmed | Double deletion of Panx1 and Panx3 affects skin and bone but not hearing. | 3.44e-06 | 2 | 65 | 2 | 30918989 | |
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 14985349 | ||
| Pubmed | Ryanodine receptors in human pancreatic beta cells: localization and effects on insulin secretion. | 3.44e-06 | 2 | 65 | 2 | 15033925 | |
| Pubmed | Regulation of bestrophins by Ca2+: a theoretical and experimental study. | 3.44e-06 | 2 | 65 | 2 | 19262692 | |
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 19398034 | ||
| Pubmed | Thermodynamics of calmodulin binding to cardiac and skeletal muscle ryanodine receptor ion channels. | 3.44e-06 | 2 | 65 | 2 | 18618700 | |
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 17591909 | ||
| Pubmed | Expression and functional activity of ryanodine receptors (RyRs) during skeletal muscle development. | 3.44e-06 | 2 | 65 | 2 | 17118445 | |
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 22947051 | ||
| Pubmed | RyR3 amplifies RyR1-mediated Ca(2+)-induced Ca(2+) release in neonatal mammalian skeletal muscle. | 3.44e-06 | 2 | 65 | 2 | 11500519 | |
| Pubmed | DEFOG: a practical scheme for deciphering families of genes. | 3.53e-06 | 219 | 65 | 6 | 12213199 | |
| Pubmed | 7.42e-06 | 143 | 65 | 5 | 20424473 | ||
| Pubmed | The repertoire of solute carriers of family 6: identification of new human and rodent genes. | 8.09e-06 | 21 | 65 | 3 | 16125675 | |
| Pubmed | 1.03e-05 | 3 | 65 | 2 | 11171121 | ||
| Pubmed | The mammalian pannexin family is homologous to the invertebrate innexin gap junction proteins. | 1.03e-05 | 3 | 65 | 2 | 15028292 | |
| Pubmed | Differential effects of pannexins on noise-induced hearing loss. | 1.03e-05 | 3 | 65 | 2 | 27784763 | |
| Pubmed | The role of Pannexin gene variants in schizophrenia: systematic analysis of phenotypes. | 1.03e-05 | 3 | 65 | 2 | 26223428 | |
| Pubmed | 1.03e-05 | 3 | 65 | 2 | 18313230 | ||
| Pubmed | Control of Neuronal Ryanodine Receptor-Mediated Calcium Signaling by Calsenilin. | 1.03e-05 | 3 | 65 | 2 | 29730765 | |
| Pubmed | 1.03e-05 | 3 | 65 | 2 | 29357945 | ||
| Pubmed | 1.03e-05 | 3 | 65 | 2 | 24123915 | ||
| Interaction | NPLOC4 interactions | 1.67e-05 | 199 | 55 | 6 | int:NPLOC4 | |
| Interaction | PKMYT1 interactions | 3.96e-05 | 140 | 55 | 5 | int:PKMYT1 | |
| Interaction | AUP1 interactions | 4.14e-05 | 234 | 55 | 6 | int:AUP1 | |
| Cytoband | 11p14.2 | 4.13e-05 | 7 | 65 | 2 | 11p14.2 | |
| Cytoband | 11q21 | 1.80e-03 | 44 | 65 | 2 | 11q21 | |
| Cytoband | 19p13.1 | 2.13e-03 | 48 | 65 | 2 | 19p13.1 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr11p14 | 3.31e-03 | 60 | 65 | 2 | chr11p14 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr11q21 | 3.65e-03 | 63 | 65 | 2 | chr11q21 | |
| Cytoband | 12q13 | 4.61e-03 | 71 | 65 | 2 | 12q13 | |
| GeneFamily | Bestrophins | 7.66e-11 | 4 | 55 | 4 | 866 | |
| GeneFamily | Ryanodine receptors|Protein phosphatase 1 regulatory subunits | 2.66e-08 | 3 | 55 | 3 | 287 | |
| GeneFamily | Solute carriers | SLC6A6 SLC24A4 SLC6A20 SLC6A19 SLC5A12 SLC5A8 SLC1A3 SLC30A10 | 2.40e-05 | 395 | 55 | 8 | 752 |
| GeneFamily | Pannexins | 2.72e-05 | 3 | 55 | 2 | 288 | |
| GeneFamily | Transmembrane BAX inhibitor motif containing | 1.35e-04 | 6 | 55 | 2 | 1215 | |
| GeneFamily | Anoctamins | 4.03e-04 | 10 | 55 | 2 | 865 | |
| GeneFamily | Olfactory receptors, family 6 | 5.00e-04 | 51 | 55 | 3 | 153 | |
| GeneFamily | Olfactory receptors, family 10 | 1.06e-03 | 66 | 55 | 3 | 157 | |
| GeneFamily | CD molecules|Tetraspanins | 4.52e-03 | 33 | 55 | 2 | 768 | |
| GeneFamily | Olfactory receptors, family 5 | 4.80e-03 | 112 | 55 | 3 | 152 | |
| ToppCell | Globus_pallidus-Neuronal-Excitatory|Globus_pallidus / BrainAtlas - Mouse McCarroll V32 | 3.71e-06 | 160 | 65 | 5 | f843287ed57d2d5a3b3f6dfb03b6934e330e6645 | |
| ToppCell | Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32 | 3.83e-06 | 161 | 65 | 5 | ebcd5066e82b7760b9da6adc02d11258d1309dab | |
| ToppCell | facs-Brain_Non-Myeloid-Striatum|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 9.24e-06 | 193 | 65 | 5 | d8ccfb780a75bdf9141f41fb29a076958601ebb4 | |
| ToppCell | Monocytes-NUPR1+_Monocytes|Monocytes / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues | 1.02e-05 | 197 | 65 | 5 | 8a058c9d9285acd7cf2fb8e34f7602a86b5d6c89 | |
| Computational | Vesicular transport / synapse genes. | 1.23e-04 | 82 | 34 | 4 | MODULE_274 | |
| Drug | IAA-94 | 3.42e-10 | 61 | 63 | 7 | CID000003667 | |
| Drug | 2-hydroxycarbazole | 2.02e-08 | 3 | 63 | 3 | CID000093551 | |
| Drug | cis-diammineplatinum(II | 2.02e-08 | 3 | 63 | 3 | CID000159790 | |
| Drug | 2-hydroxyheptanoic acid | 2.02e-08 | 3 | 63 | 3 | CID002750949 | |
| Drug | Ryanodyl 3-(pyridine-3-carboxylate | 2.02e-08 | 3 | 63 | 3 | CID005748312 | |
| Drug | 8N3-cADPR | 2.02e-08 | 3 | 63 | 3 | CID000127713 | |
| Drug | aminodantrolene | 2.02e-08 | 3 | 63 | 3 | CID009570289 | |
| Drug | PCB74 | 8.06e-08 | 4 | 63 | 3 | CID000036218 | |
| Drug | 148504-47-6 | 8.06e-08 | 4 | 63 | 3 | CID006444275 | |
| Drug | SC 38249 | 8.06e-08 | 4 | 63 | 3 | CID000134834 | |
| Drug | AC1L1U7A | 8.06e-08 | 4 | 63 | 3 | CID000035682 | |
| Drug | kazinol B | 1.23e-07 | 17 | 63 | 4 | CID000480869 | |
| Drug | MBED | 4.01e-07 | 6 | 63 | 3 | CID000129958 | |
| Drug | chloro-m-cresol | 4.01e-07 | 6 | 63 | 3 | CID000012008 | |
| Drug | AC1O528X | 4.01e-07 | 6 | 63 | 3 | CID006475857 | |
| Drug | NSC114784 | 4.01e-07 | 6 | 63 | 3 | CID000419425 | |
| Drug | Azumoleno | 7.01e-07 | 7 | 63 | 3 | CID000056259 | |
| Drug | Br2BAPTA | 7.01e-07 | 7 | 63 | 3 | CID003081001 | |
| Drug | [[(2R,3S,4R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methyl hydrogen phosphate | 7.01e-07 | 7 | 63 | 3 | CID009547999 | |
| Drug | 2,4-xylidinothiazoline | 1.38e-06 | 30 | 63 | 4 | CID000099296 | |
| Drug | pimozide | 1.40e-06 | 127 | 63 | 6 | CID000016362 | |
| Drug | sodium | SLC6A6 ATP7B SLC24A4 SLC6A20 PKD1 KCNMB1 SLC5A12 SLC5A8 LCK SLC1A3 RYR1 RYR2 RYR3 | 1.50e-06 | 944 | 63 | 13 | CID000000923 |
| Drug | CAS 298-57-7 | 1.79e-06 | 73 | 63 | 5 | CID000002761 | |
| Drug | CNS 1145 | 2.05e-06 | 33 | 63 | 4 | CID000190902 | |
| Drug | IHC-64 | 2.05e-06 | 33 | 63 | 4 | CID000162753 | |
| Drug | CsCl | 2.09e-06 | 136 | 63 | 6 | CID000024293 | |
| Drug | PCB 95 | 2.39e-06 | 10 | 63 | 3 | CID000038012 | |
| Drug | PCB 66 | 3.28e-06 | 11 | 63 | 3 | CID000036185 | |
| Drug | R 478 | 3.28e-06 | 11 | 63 | 3 | CID000084223 | |
| Drug | 8-amino-cADPR | 3.28e-06 | 11 | 63 | 3 | CID003081323 | |
| Drug | Ryanodine | 4.36e-06 | 12 | 63 | 3 | ctd:D012433 | |
| Drug | gamma-aminobutyric acid | 5.95e-06 | 474 | 63 | 9 | CID000000119 | |
| Drug | isotetrandrine | 7.31e-06 | 97 | 63 | 5 | CID000005422 | |
| Drug | 5'-adenylyl (beta,gamma-methylene)diphosphonate | 7.54e-06 | 2 | 63 | 2 | ctd:C005147 | |
| Drug | FPL 64176 | 8.97e-06 | 15 | 63 | 3 | CID000003423 | |
| Drug | Gvapspat amide | 8.97e-06 | 15 | 63 | 3 | CID000125015 | |
| Drug | ts M | 9.45e-06 | 48 | 63 | 4 | CID000428025 | |
| Drug | Trp-Trp | 1.03e-05 | 49 | 63 | 4 | CID000088656 | |
| Drug | loperamide | 1.08e-05 | 105 | 63 | 5 | CID000003954 | |
| Drug | baclofen | 1.47e-05 | 191 | 63 | 6 | CID000002284 | |
| Drug | AC1L1KF5 | 1.54e-05 | 113 | 63 | 5 | CID000005470 | |
| Drug | creatine | 1.56e-05 | 193 | 63 | 6 | CID000000586 | |
| Drug | methylcoumarin | 1.60e-05 | 18 | 63 | 3 | CID000007092 | |
| Drug | Cinildipine | 1.75e-05 | 56 | 63 | 4 | CID000002752 | |
| Drug | AC1L380G | 1.90e-05 | 19 | 63 | 3 | CID000084698 | |
| Drug | AC1MW7VF | 1.90e-05 | 19 | 63 | 3 | CID000414699 | |
| Drug | Baclofen | 2.23e-05 | 20 | 63 | 3 | ctd:D001418 | |
| Drug | 1,1'-diheptyl-4,4'-bipyridinium | 2.26e-05 | 3 | 63 | 2 | CID000080262 | |
| Drug | flubendiamide | 2.26e-05 | 3 | 63 | 2 | CID011193251 | |
| Drug | nilvadipine | 2.31e-05 | 60 | 63 | 4 | CID000004494 | |
| Drug | niflumic acid | 2.51e-05 | 125 | 63 | 5 | CID000004488 | |
| Drug | indo-1/AM | 2.59e-05 | 21 | 63 | 3 | CID000123918 | |
| Drug | lercanidipine | 2.80e-05 | 63 | 63 | 4 | CID000065866 | |
| Drug | gallopamil | 3.58e-05 | 67 | 63 | 4 | CID000001234 | |
| Drug | lanthanum | 3.76e-05 | 136 | 63 | 5 | CID000023926 | |
| Drug | AC1L2AC7 | 4.02e-05 | 69 | 63 | 4 | CID000068733 | |
| Drug | T0702 | 4.45e-05 | 25 | 63 | 3 | CID000005908 | |
| Drug | A-30 | 4.51e-05 | 4 | 63 | 2 | CID003028528 | |
| Drug | Bastadin 10 | 4.51e-05 | 4 | 63 | 2 | CID009589366 | |
| Drug | ethosuximide | 5.30e-05 | 74 | 63 | 4 | CID000003291 | |
| Drug | nisoldipine | 6.51e-05 | 78 | 63 | 4 | CID000004499 | |
| Drug | N-cyclopentyl-N-cyclobutylformamide | 6.84e-05 | 79 | 63 | 4 | CID005287890 | |
| Drug | caged InsP3 | 7.01e-05 | 29 | 63 | 3 | CID000122248 | |
| Drug | myo-inositol | 7.19e-05 | 811 | 63 | 10 | CID000000892 | |
| Drug | AC1NSZ76 | 7.50e-05 | 5 | 63 | 2 | CID005320215 | |
| Drug | A 68930 | 7.50e-05 | 5 | 63 | 2 | ctd:C065380 | |
| Drug | N-methyl-DL-aspartic acid | 7.55e-05 | 655 | 63 | 9 | CID000004376 | |
| Drug | CHAPS detergent | 7.67e-05 | 158 | 63 | 5 | CID000107670 | |
| Drug | LOPAC | 7.77e-05 | 30 | 63 | 3 | CID000062696 | |
| Drug | M-HN | 8.59e-05 | 31 | 63 | 3 | CID000015450 | |
| Drug | M3/M4 | 9.46e-05 | 32 | 63 | 3 | CID000486507 | |
| Drug | lavendustin A | 1.11e-04 | 171 | 63 | 5 | CID000003894 | |
| Drug | NSC692750 | 1.12e-04 | 6 | 63 | 2 | CID000078910 | |
| Drug | riluzole | 1.21e-04 | 174 | 63 | 5 | CID000005070 | |
| Drug | AC1NUZ8M | 1.24e-04 | 92 | 63 | 4 | CID000073211 | |
| Drug | manidipine | 1.40e-04 | 95 | 63 | 4 | CID000004008 | |
| Drug | 1,2-dichlorohexafluorocyclobutane | 1.47e-04 | 37 | 63 | 3 | CID000009643 | |
| Drug | mag-fura-2 | 1.47e-04 | 37 | 63 | 3 | CID000123839 | |
| Drug | 4-chloro-m-cresol | 1.47e-04 | 37 | 63 | 3 | CID000001732 | |
| Drug | mag-indo-1 | 1.57e-04 | 7 | 63 | 2 | CID000131881 | |
| Drug | CHEBI:564108 | 1.57e-04 | 7 | 63 | 2 | CID006400637 | |
| Drug | nitrendipine | 1.58e-04 | 98 | 63 | 4 | CID000004507 | |
| Drug | AC1L98DX | 1.59e-04 | 38 | 63 | 3 | CID000439957 | |
| Drug | isradipine | 1.71e-04 | 100 | 63 | 4 | CID000003784 | |
| Drug | NAADP | 1.72e-04 | 39 | 63 | 3 | CID000123952 | |
| Drug | dipyrone | 1.85e-04 | 40 | 63 | 3 | CID000003110 | |
| Drug | NSC759576 | 1.87e-04 | 191 | 63 | 5 | CID000003075 | |
| Drug | Dantrolene | 2.00e-04 | 41 | 63 | 3 | ctd:D003620 | |
| Drug | Acrylamide | 2.26e-04 | 199 | 63 | 5 | ctd:D020106 | |
| Drug | betaine | 2.31e-04 | 200 | 63 | 5 | CID000000247 | |
| Drug | escina | 2.47e-04 | 44 | 63 | 3 | CID006433489 | |
| Drug | fentanyl | 2.55e-04 | 111 | 63 | 4 | CID000003345 | |
| Drug | 4,4'-dithiodipyridine | 2.64e-04 | 45 | 63 | 3 | CID000075846 | |
| Drug | 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid | 2.65e-04 | 206 | 63 | 5 | CID000040600 | |
| Drug | C13932 | 2.65e-04 | 206 | 63 | 5 | CID000168297 | |
| Drug | lactosyl lysosphingolipid | 2.68e-04 | 9 | 63 | 2 | CID006439268 | |
| Drug | FLA 365 | 2.68e-04 | 9 | 63 | 2 | CID000072776 | |
| Drug | pioglitazone | 2.82e-04 | 326 | 63 | 6 | CID000004829 | |
| Drug | KB-R7943 | 3.00e-04 | 47 | 63 | 3 | CID004534086 | |
| Drug | lamotrigine | 3.02e-04 | 116 | 63 | 4 | CID000003878 | |
| Disease | congenital myopathy 1A (implicated_via_orthology) | 6.47e-09 | 3 | 56 | 3 | DOID:3529 (implicated_via_orthology) | |
| Disease | malignant hyperthermia (implicated_via_orthology) | 6.47e-09 | 3 | 56 | 3 | DOID:8545 (implicated_via_orthology) | |
| Disease | HYPERGLYCINURIA (disorder) | 1.06e-05 | 3 | 56 | 2 | C0543541 | |
| Disease | Iminoglycinuria | 2.12e-05 | 4 | 56 | 2 | C0268654 | |
| Disease | polyunsaturated fatty acids to monounsaturated fatty acids ratio | 1.26e-04 | 51 | 56 | 3 | EFO_0022302 | |
| Disease | Parkinson's disease (implicated_via_orthology) | 2.28e-04 | 157 | 56 | 4 | DOID:14330 (implicated_via_orthology) | |
| Disease | monounsaturated fatty acids; 16:1, 18:1 measurement | 4.45e-04 | 78 | 56 | 3 | EFO_0022187 | |
| Disease | Dystonia, Limb | 4.72e-04 | 17 | 56 | 2 | C0751093 | |
| Disease | Dystonia, Diurnal | 4.72e-04 | 17 | 56 | 2 | C0393610 | |
| Disease | pulmonary hypertension (biomarker_via_orthology) | 4.80e-04 | 80 | 56 | 3 | DOID:6432 (biomarker_via_orthology) | |
| Disease | alcohol use disorder (implicated_via_orthology) | 5.19e-04 | 195 | 56 | 4 | DOID:1574 (implicated_via_orthology) | |
| Disease | Dystonia, Paroxysmal | 5.31e-04 | 18 | 56 | 2 | C0393588 | |
| Disease | Dyslipidemias | 9.51e-04 | 24 | 56 | 2 | C0242339 | |
| Disease | Anhedonia | 9.51e-04 | 24 | 56 | 2 | C0178417 | |
| Disease | Dyslipoproteinemias | 9.51e-04 | 24 | 56 | 2 | C0598784 | |
| Disease | Liver Failure, Acute | 9.51e-04 | 24 | 56 | 2 | C0162557 | |
| Disease | cholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement | 1.00e-03 | 103 | 56 | 3 | EFO_0008595, EFO_0020944 | |
| Disease | Liver Cirrhosis | 1.00e-03 | 103 | 56 | 3 | C0023890 | |
| Disease | Fibrosis, Liver | 1.06e-03 | 105 | 56 | 3 | C0239946 | |
| Disease | congestive heart failure (is_implicated_in) | 1.20e-03 | 27 | 56 | 2 | DOID:6000 (is_implicated_in) | |
| Disease | sleep duration, high density lipoprotein cholesterol measurement | 1.59e-03 | 121 | 56 | 3 | EFO_0004612, EFO_0005271 | |
| Disease | hypertension (implicated_via_orthology) | 1.87e-03 | 128 | 56 | 3 | DOID:10763 (implicated_via_orthology) |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| GYVVLIVVAIFVLVA | 1271 | Q5DID0 | |
| LLVFVTEVVVVVLGY | 91 | O60637 | |
| GIPLVYTQVVTLAVY | 231 | Q8N1M1 | |
| SIPLVYTQVVTIAVY | 231 | Q8NFU0 | |
| SVPLVYTQVVTIALY | 231 | Q8NFU1 | |
| QGYIEYSVAIIILTV | 221 | Q4VNC0 | |
| VLIVLATSIAYVYSL | 731 | P35670 | |
| ATSIAYVYSLVILVV | 736 | P35670 | |
| SIPLVYTQVVTVAVY | 231 | O76090 | |
| VITAVFGVVVYRLVV | 561 | Q9BYT9 | |
| DSVYYTISVIVLIVF | 206 | Q8NFF2 | |
| LVVVSYFLITGGIIY | 36 | Q9NRP0 | |
| VTMVVCAVITYYILV | 21 | Q16558 | |
| CAVITYYILVTTVLP | 26 | Q16558 | |
| ILLATLYVAVTVPYS | 231 | Q9ULD8 | |
| SVLLYVPSIIYAIVI | 356 | Q9NW15 | |
| VCGVVYTLLQSIISY | 131 | Q8N682 | |
| IIVIIVSYMYIVSTV | 236 | Q8NGE7 | |
| SYIIVDVILIASSYV | 206 | Q8NGH9 | |
| IGTVLISYIFVLYTI | 211 | A6NHG9 | |
| GVYTIFAILEYTVVL | 211 | Q9UHJ9 | |
| LTVVVVHYGFASVIY | 246 | Q8NGA6 | |
| LIVVIVHYGFASVIY | 246 | O60403 | |
| IIIPVTVYYSVIEAT | 166 | Q96P67 | |
| LVTGIVTSIVLYFQY | 231 | Q969X1 | |
| TVAVVVTFYDVYIIL | 111 | Q9HC24 | |
| GHLVYVLVYNITTVI | 201 | Q14439 | |
| LYVIIATFVIVVALG | 931 | Q8IZA0 | |
| VIYIITVVGYVLIVV | 31 | A6NHA9 | |
| SVLVVLISYGYIVAA | 211 | Q8NGI9 | |
| VRLYAVVTQEPIYII | 301 | P06239 | |
| LVVYVLLAPVVVYTL | 281 | Q96RD7 | |
| LAVVSLFYGTVIAVY | 246 | Q8NGR3 | |
| VTVISVSYYYIILTI | 211 | Q8NGZ9 | |
| SVAIYTILVPVIIYN | 276 | Q96QZ0 | |
| TVLVALTYIVALLYE | 166 | Q9UBM1 | |
| VTLISYGYIVTTVLR | 211 | Q8N148 | |
| IDINGYILVYSVTSI | 76 | Q15382 | |
| LSLVGQVYSTLVTYI | 2536 | P04114 | |
| YYMTTTIIAVVIGII | 126 | P43003 | |
| LVGTVTRTYYIGIVE | 21 | Q6MZM0 | |
| TYLATAYILVVAGTV | 56 | P48509 | |
| VVSLVLVTIYADYIA | 206 | O75844 | |
| TVGLLAVVVYLYTVV | 4841 | P21817 | |
| VGLLAVVVYLYTVVA | 4771 | Q92736 | |
| GAIYYVVFTTLVLLA | 261 | Q7RTP0 | |
| LELSVVGVSLTYYAV | 2561 | Q8TDX9 | |
| IAETSLTIDGIYYVV | 841 | Q14562 | |
| FGVTVLVYARIYVVL | 201 | P35462 | |
| GLVSSVVVYPVYLAI | 3326 | P98161 | |
| LTVVVVHYGFASVIY | 246 | Q9Y4A9 | |
| IITAVYSVVFVVGLV | 61 | P41145 | |
| TVVIIFYGTIIYVYL | 246 | Q8NGZ4 | |
| GFTSVYVAIVVYSVI | 311 | Q695T7 | |
| YVAIVVYSVIGFRAT | 316 | Q695T7 | |
| ASVVIVSLLNVYYIV | 126 | P31641 | |
| YVITAFSVLTGVVYL | 106 | Q8TEB9 | |
| IVQTILYTGIVIYAP | 136 | Q8N695 | |
| TVVVIIYGSSIFLYI | 246 | Q8NGN1 | |
| IIVATVCVIAISYIY | 206 | Q8WZ94 | |
| VCVIAISYIYILITI | 211 | Q8WZ94 | |
| VLVAYSYTYIILTIV | 211 | Q8NGC5 | |
| LIVLVETIAVCYVYG | 471 | Q9NP91 | |
| GSVVVVITAIIFYVL | 251 | Q6XR72 | |
| VLTVGLLAVVVYLYT | 4671 | Q15413 | |
| VVGSELVDTYTVYII | 21 | Q9Y2I1 | |
| VRTLVTRVITDVYYV | 1246 | Q12888 | |
| AATVIYIVQTILYTG | 126 | Q1EHB4 | |
| YVLRVGGLVYTITDV | 186 | Q9UBP6 |