Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesshead development

FOXO3 HSPG2 KIF26A GATA2 AKNA MECOM POU3F1 POU3F2 SRGAP2 STIL NR2F2 FOXB1 TTBK1 CDK2AP1 ZIC5 SEC24B LHX5 TBR1 NEUROD6 ATP2B2 TBX1

4.28e-0991910321GO:0060322
GeneOntologyBiologicalProcessbrain development

FOXO3 HSPG2 KIF26A GATA2 AKNA MECOM POU3F1 POU3F2 SRGAP2 STIL NR2F2 FOXB1 TTBK1 ZIC5 SEC24B LHX5 TBR1 NEUROD6 ATP2B2

4.39e-0885910319GO:0007420
GeneOntologyBiologicalProcessforebrain development

KIF26A GATA2 AKNA MECOM POU3F1 POU3F2 SRGAP2 STIL NR2F2 FOXB1 ZIC5 LHX5 TBR1 NEUROD6

1.47e-0748910314GO:0030900
GeneOntologyBiologicalProcesscentral nervous system development

FOXO3 HSPG2 KIF26A GATA2 AKNA MECOM POU3F1 POU3F2 SRGAP2 PPP1R17 STIL NR2F2 FOXB1 TTBK1 ZIC5 SEC24B LHX5 TBR1 NEUROD6 ATP2B2 TBX1

3.87e-07119710321GO:0007417
Domain-

ASF1B ASF1A

3.01e-05210322.60.40.1490
DomainASF1_hist_chap

ASF1B ASF1A

3.01e-0521032PF04729
DomainASF1-like

ASF1B ASF1A

3.01e-0521032IPR006818
DomainTF_POU_3

POU3F1 POU3F2

1.79e-0441032IPR016362
Domain-

HSPG2 TMPRSS13 MALRD1

2.08e-034610334.10.400.10
DomainLDLRA_1

HSPG2 TMPRSS13 MALRD1

2.35e-03481033PS01209
DomainLDLRA_2

HSPG2 TMPRSS13 MALRD1

2.50e-03491033PS50068
DomainLDrepeatLR_classA_rpt

HSPG2 TMPRSS13 MALRD1

2.50e-03491033IPR002172
DomainLDLa

HSPG2 TMPRSS13 MALRD1

2.50e-03491033SM00192
DomainPOU

POU3F1 POU3F2

3.44e-03161032SM00352
DomainPOU_2

POU3F1 POU3F2

3.44e-03161032PS00465
DomainPOU_dom

POU3F1 POU3F2

3.44e-03161032IPR000327
DomainPOU_3

POU3F1 POU3F2

3.44e-03161032PS51179
DomainPou

POU3F1 POU3F2

3.44e-03161032PF00157
DomainPOU_1

POU3F1 POU3F2

3.44e-03161032PS00035
DomainHomeobox_CS

POU3F1 POU3F2 IRX1 NKX2-4 LHX5

3.70e-031861035IPR017970
DomainTF_T-box

TBR1 TBX1

3.88e-03171032IPR001699
DomainTBOX

TBR1 TBX1

3.88e-03171032SM00425
DomainTF_T-box_CS

TBR1 TBX1

3.88e-03171032IPR018186
Domain-

TBR1 TBX1

3.88e-031710322.60.40.820
DomainPOU

POU3F1 POU3F2

3.88e-03171032IPR013847
DomainTBOX_3

TBR1 TBX1

3.88e-03171032PS50252
DomainT-box

TBR1 TBX1

3.88e-03171032PF00907
DomainTBOX_1

TBR1 TBX1

3.88e-03171032PS01283
DomainTBOX_2

TBR1 TBX1

3.88e-03171032PS01264
DomainCation_ATPase_N

ATP13A4 ATP2B2

4.35e-03181032PF00690
DomainCation_ATPase_N

ATP13A4 ATP2B2

4.35e-03181032SM00831
DomainPept_M10A_stromelysin-type

MMP25 MMP15

4.35e-03181032IPR016293
DomainATPase_P-typ_cation-transptr_N

ATP13A4 ATP2B2

4.84e-03191032IPR004014
DomainPG_binding_1

MMP25 MMP15

5.36e-03201032PF01471
DomainPeptidoglycan-bd-like

MMP25 MMP15

5.36e-03201032IPR002477
DomainFA58C

F8 CPXM1

5.91e-03211032SM00231
DomainFA58C_3

F8 CPXM1

5.91e-03211032PS50022
DomainFA58C_1

F8 CPXM1

5.91e-03211032PS01285
DomainFA58C_2

F8 CPXM1

5.91e-03211032PS01286
PathwayWP_WHITE_FAT_CELL_DIFFERENTIATION

GATA2 SREBF1 MECOM NR2F2

1.70e-0532694M39333
PathwayWP_WHITE_FAT_CELL_DIFFERENTIATION

GATA2 SREBF1 MECOM NR2F2

1.93e-0533694MM15869
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

HSPG2 COL15A1 ADAMTS4 MMP25 CD44 MMP15

6.18e-05140696M587
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

COL15A1 ADAMTS4 MMP25 CD44 MMP15

2.36e-04114695MM14571
Pubmed

A census of human transcription factors: function, expression and evolution.

FOXO3 KLF11 GATA2 SREBF1 AKNA POU3F1 POU3F2 IRX1 NR2F2 FOXB1 NKX2-4 LHX5 TBR1 NEUROD6 TBX1

1.29e-079081071519274049
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FOXO3 HSPG2 SYNRG KIF26A SPEG GATA2 SREBF1 DYRK1A AKNA SRGAP2 ATG2A ITGB4 NR2F2 RHPN1 URB1 TMCC2

2.79e-0711051071635748872
Pubmed

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

FOXO3 KLF11 GATA2 SREBF1 POU3F1 POU3F2 IRX1 FOXB1 ZIC5 LHX5 TBX1

9.93e-075441071128473536
Pubmed

The Transcription Factor Pou3f1 Sheds Light on the Development and Molecular Diversity of Glutamatergic Cerebellar Nuclear Neurons in the Mouse.

POU3F1 POU3F2 TBR1

1.57e-068107335935334
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

FOXO3 SYNRG FAM184A MIA3 L3MBTL2 ACOT9 DYRK1A ATG2A STIL KIF7 SEC24B USP54 PPP6R2

2.30e-068531071328718761
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

HSPG2 KLF11 NOXA1 SREBF1 TNIP1 ITGB4 ARID5A RNF220 USP54 R3HDM1 PPP6R2

2.90e-066081071116713569
Pubmed

Olig3 regulates early cerebellar development.

SREBF1 POU3F2 TBR1 NEUROD6

7.11e-0640107433591268
Pubmed

Characterization of Olig2 expression during cerebellar development.

POU3F2 LHX5 TBR1

7.92e-0613107324594479
Pubmed

FOXO3 is essential for CD44 expression in pancreatic cancer cells.

FOXO3 CD44

9.38e-062107227893718
Pubmed

A single oncogenic enhancer rearrangement causes concomitant EVI1 and GATA2 deregulation in leukemia.

GATA2 MECOM

9.38e-062107224703711
Pubmed

A remote GATA2 hematopoietic enhancer drives leukemogenesis in inv(3)(q21;q26) by activating EVI1 expression.

GATA2 MECOM

9.38e-062107224703906
Pubmed

Evi-1 promotes para-aortic splanchnopleural hematopoiesis through up-regulation of GATA-2 and repression of TGF-b signaling.

GATA2 MECOM

9.38e-062107218452556
Pubmed

Distinct role of histone chaperone Asf1a and Asf1b during fertilization and pre-implantation embryonic development in mice.

ASF1B ASF1A

9.38e-062107234906203
Pubmed

Striated muscle preferentially expressed genes alpha and beta are two serine/threonine protein kinases derived from the same gene as the aortic preferentially expressed gene-1.

KLF11 SPEG

9.38e-062107210973969
Pubmed

EVI1 and GATA2 misexpression induced by inv(3)(q21q26) contribute to megakaryocyte-lineage skewing and leukemogenesis.

GATA2 MECOM

9.38e-062107232330245
Pubmed

Regulation of replication fork progression through histone supply and demand.

ASF1B ASF1A

9.38e-062107218096807
Pubmed

GATA2 haploinsufficiency accelerates EVI1-driven leukemogenesis.

GATA2 MECOM

9.38e-062107228630119
Pubmed

Cav1.2 calcium channels modulate the spiking pattern of hippocampal pyramidal cells.

CACNA1C NEUROD6

9.38e-062107218045623
Pubmed

Elevated expression of ASF1B correlates with poor prognosis in human lung adenocarcinoma.

ASF1B ASF1A

9.38e-062107233576264
Pubmed

Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1.

ASF1B ASF1A

9.38e-062107224413054
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

FOXO3 MIA3 MPDZ SRGAP2 GTF3C4 KIF7 USP54 R3HDM1 PPP6R2

1.02e-05446107924255178
Pubmed

Satb2 is a postmitotic determinant for upper-layer neuron specification in the neocortex.

POU3F1 POU3F2 TBR1

1.25e-0515107318255031
Pubmed

Single-cell transcriptomic analysis of mouse neocortical development.

GATA2 POU3F1 CD44 LHX5 TBR1 NEUROD6

1.50e-05170107630635555
Pubmed

The winged helix gene, Mf3, is required for normal development of the diencephalon and midbrain, postnatal growth and the milk-ejection reflex.

POU3F1 POU3F2 FOXB1

1.54e-051610739118797
Pubmed

A stream of cells migrating from the caudal telencephalon reveals a link between the amygdala and neocortex.

POU3F1 TBR1 NEUROD6

1.87e-0517107317694053
Pubmed

Spatially restricted and developmentally dynamic expression of engrailed genes in multiple cerebellar cell types.

POU3F2 LHX5 TBR1

1.87e-0517107321431469
Pubmed

Fstl1 is involved in the regulation of radial glial scaffold development.

POU3F2 NR2F2 TBR1

1.87e-0517107326382033
Pubmed

Transcriptional repression by FEZF2 restricts alternative identities of cortical projection neurons.

KIF26A TBR1 NEUROD6

2.23e-0518107334161768
Pubmed

PRDM16 regulates a temporal transcriptional program to promote progression of cortical neural progenitors.

POU3F1 POU3F2 TBR1

2.65e-0519107333597191
Pubmed

Sim1-expressing cells illuminate the origin and course of migration of the nucleus of the lateral olfactory tract in the mouse amygdala.

POU3F2 TBR1 NEUROD6

2.65e-0519107333492553
Pubmed

Single-cell transcriptomics of the early developing mouse cerebral cortex disentangle the spatial and temporal components of neuronal fate acquisition.

NR2F2 LHX5 TBR1 NEUROD6

2.75e-0556107434170322
Pubmed

Cacna1c deficiency in forebrain glutamatergic neurons alters behavior and hippocampal plasticity in female mice.

CACNA1C NEUROD6

2.81e-053107239370418
Pubmed

Leukocyte Cytoskeleton Polarization Is Initiated by Plasma Membrane Curvature from Cell Attachment.

SRGAP2 RPH3A

2.81e-053107230930167
Pubmed

Tachypacing-induced CREB/CD44 signaling contributes to the suppression of L-type calcium channel expression and the development of atrial remodeling.

CACNA1C CD44

2.81e-053107234023501
Pubmed

Structural plasticity of histones H3-H4 facilitates their allosteric exchange between RbAp48 and ASF1.

ASF1B ASF1A

2.81e-053107223178455
Pubmed

RIF1-ASF1-mediated high-order chromatin structure safeguards genome integrity.

ASF1B ASF1A

2.81e-053107235177609
Pubmed

Transcriptional regulation of human chromatin assembly factor ASF1.

ASF1B ASF1A

2.81e-053107217328667
Pubmed

Critical role of miR-9 in myelopoiesis and EVI1-induced leukemogenesis.

FOXO3 MECOM

2.81e-053107223509296
Pubmed

Tousled-like kinases phosphorylate Asf1 to promote histone supply during DNA replication.

ASF1B ASF1A

2.81e-053107224598821
Pubmed

In vivo study of the nucleosome assembly functions of ASF1 histone chaperones in human cells.

ASF1B ASF1A

2.81e-053107218378699
Pubmed

Tousled-like kinase 2 targets ASF1 histone chaperones through client mimicry.

ASF1B ASF1A

2.81e-053107235136069
Pubmed

TLK1B promotes repair of UV-damaged DNA through chromatin remodeling by Asf1.

ASF1B ASF1A

2.81e-053107217054786
Pubmed

Memo1-Mediated Tiling of Radial Glial Cells Facilitates Cerebral Cortical Development.

POU3F2 TBR1 NEUROD6

3.11e-0520107331277925
Pubmed

Loss of BAF Complex in Developing Cortex Perturbs Radial Neuronal Migration in a WNT Signaling-Dependent Manner.

POU3F2 TBR1 NEUROD6

3.11e-0520107334220450
Pubmed

Bcl11a (Ctip1) Controls Migration of Cortical Projection Neurons through Regulation of Sema3c.

POU3F2 TBR1 NEUROD6

4.18e-0522107326182416
Pubmed

Olig2 regulates Purkinje cell generation in the early developing mouse cerebellum.

POU3F2 LHX5 TBR1

4.18e-0522107327469598
Pubmed

The Epigenetic State of PRDM16-Regulated Enhancers in Radial Glia Controls Cortical Neuron Position.

POU3F2 TBR1 NEUROD6

4.18e-0522107329779941
Pubmed

Zic deficiency in the cortical marginal zone and meninges results in cortical lamination defects resembling those in type II lissencephaly.

HSPG2 POU3F1 TBR1

4.18e-0522107318448648
Pubmed

The doublesex homolog Dmrt5 is required for the development of the caudomedial cerebral cortex in mammals.

POU3F1 LHX5 TBR1 NEUROD6

4.39e-0563107422923088
Pubmed

Serum response factor is required for cortical axon growth but is dispensable for neurogenesis and neocortical lamination.

LHX5 TBR1 NEUROD6

4.79e-0523107322090492
Pubmed

Local regulation of fat metabolism in peripheral nerves.

SREBF1 POU3F1 ITGB4

4.79e-0523107314522948
Pubmed

Sequential phases of cortical specification involve Neurogenin-dependent and -independent pathways.

POU3F1 TBR1 NEUROD6

4.79e-0523107315229646
Pubmed

Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development.

POU3F1 POU3F2 TBR1 NEUROD6

4.96e-0565107426655900
Pubmed

Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways.

FOXO3 POU3F1 POU3F2 TBR1 NEUROD6

5.29e-05130107519386638
Pubmed

TLK1B promotes repair of DSBs via its interaction with Rad9 and Asf1.

ASF1B ASF1A

5.60e-054107220021694
Pubmed

A POU factor binding site upstream of the Chx10 homeobox gene is required for Chx10 expression in subsets of retinal progenitor cells and bipolar cells.

POU3F1 POU3F2

5.60e-054107215893976
Pubmed

Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway.

ASF1B ASF1A

5.60e-054107211897662
Pubmed

Role of hippocampal Cav1.2 Ca2+ channels in NMDA receptor-independent synaptic plasticity and spatial memory.

CACNA1C NEUROD6

5.60e-054107216251435
Pubmed

Acetylation of lysine 564 adjacent to the C-terminal binding protein-binding motif in EVI1 is crucial for transcriptional activation of GATA2.

GATA2 MECOM

5.60e-054107220363750
Pubmed

Replication stress interferes with histone recycling and predeposition marking of new histones.

ASF1B ASF1A

5.60e-054107220227376
Pubmed

Cortical and thalamic axon pathfinding defects in Tbr1, Gbx2, and Pax6 mutant mice: evidence that cortical and thalamic axons interact and guide each other.

MPDZ TBR1

5.60e-054107211967891
Pubmed

Alpha 6 integrins participate in pro-T cell homing to the thymus.

ITGB4 F8

5.60e-05410727621877
Pubmed

Metabotropic regulation of RhoA/Rho-associated kinase by L-type Ca2+ channels: new mechanism for depolarization-evoked mammalian arterial contraction.

CACNA1C ASF1A

5.60e-054107221493898
Pubmed

An RNA interference screen uncovers a new molecule in stem cell self-renewal and long-term regeneration.

ITGB4 TBX1

5.60e-054107222495305
Pubmed

Selective influence of Sox2 on POU transcription factor binding in embryonic and neural stem cells.

POU3F1 POU3F2

5.60e-054107226265007
Pubmed

Comprehensive prediction of robust synthetic lethality between paralog pairs in cancer cell lines.

ASF1B ASF1A

5.60e-054107234529928
Pubmed

Gbx2 directly restricts Otx2 expression to forebrain and midbrain, competing with class III POU factors.

POU3F1 POU3F2

5.60e-054107222566684
Pubmed

Structure and evolution of four POU domain genes expressed in mouse brain.

POU3F1 POU3F2

5.60e-05410721565620
Pubmed

Identification of a novel LIM domain gene, LMCD1, and chromosomal localization in human and mouse.

GATA2 ATP2B2

5.60e-054107210662546
Pubmed

Structure of a human ASF1a-HIRA complex and insights into specificity of histone chaperone complex assembly.

ASF1B ASF1A

5.60e-054107216980972
Pubmed

Identification of human Asf1 chromatin assembly factors as substrates of Tousled-like kinases.

ASF1B ASF1A

5.60e-054107211470414
Pubmed

Phosphorylation-mediated control of histone chaperone ASF1 levels by Tousled-like kinases.

ASF1B ASF1A

5.60e-054107220016786
Pubmed

Molecular architecture of the developing mouse brain.

COL15A1 POU3F1 IRX1 LHX5 TBR1

5.69e-05132107534321664
Pubmed

Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways.

POU3F1 POU3F2 NR2F2 TBR1 NEUROD6

6.11e-05134107519030180
Pubmed

Zbtb20 modulates the sequential generation of neuronal layers in developing cortex.

POU3F2 TBR1 NEUROD6

6.20e-0525107327282384
Pubmed

Ccm3, a gene associated with cerebral cavernous malformations, is required for neuronal migration.

POU3F1 TBR1 NEUROD6

6.20e-0525107324595293
Pubmed

A Dynamic Unfolded Protein Response Contributes to the Control of Cortical Neurogenesis.

POU3F2 TBR1 NEUROD6

6.99e-0526107326651292
Pubmed

Cerebellar dysfunction and schizophrenia-like behavior in Ebp1-deficient mice.

MEA1 LHX5 ATP2B2

6.99e-0526107335165395
Pubmed

Role of neuroepithelial Sonic hedgehog in hypothalamic patterning.

FOXB1 LHX5 TBR1

8.77e-0528107319474326
Pubmed

COUP-TFII controls amygdala patterning by regulating neuropilin expression.

NR2F2 LHX5 TBR1

8.77e-0528107322492355
Pubmed

Chromatin regulation by BAF170 controls cerebral cortical size and thickness.

POU3F2 TBR1 NEUROD6

8.77e-0528107323643363
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

MIA3 L3MBTL2 MPDZ MECOM SRGAP2 GTF3C4 TMEM131L USP54 R3HDM1 CDC20

9.10e-057331071034672954
Pubmed

Cooperative function of POU proteins and SOX proteins in glial cells.

POU3F1 POU3F2

9.32e-05510729632656
Pubmed

FoxO1 inhibits sterol regulatory element-binding protein-1c (SREBP-1c) gene expression via transcription factors Sp1 and SREBP-1c.

FOXO3 SREBF1

9.32e-055107222511764
Pubmed

The subventricular zone is the developmental milestone of a 6-layered neocortex: comparisons in metatherian and eutherian mammals.

POU3F2 NEUROD6

9.32e-055107219726493
Pubmed

The PU.1-Modulated MicroRNA-22 Is a Regulator of Monocyte/Macrophage Differentiation and Acute Myeloid Leukemia.

GATA2 MECOM

9.32e-055107227617961
Pubmed

The class III POU factor Brn-4 interacts with other class III POU factors and the heterogeneous nuclear ribonucleoprotein U.

POU3F1 POU3F2

9.32e-05510729105675
Pubmed

The POU proteins Brn-2 and Oct-6 share important functions in Schwann cell development.

POU3F1 POU3F2

9.32e-055107212782656
Pubmed

Transcription initiation factor IID-interactive histone chaperone CIA-II implicated in mammalian spermatogenesis.

ASF1B ASF1A

9.32e-055107212842904
Pubmed

Tousled-like kinase in a microbial eukaryote regulates spindle assembly and S-phase progression by interacting with Aurora kinase and chromatin assembly factors.

ASF1B ASF1A

9.32e-055107217940067
Pubmed

Development, maturation, and necessity of transcription factors in the mouse suprachiasmatic nucleus.

POU3F1 POU3F2 NR2F2 LHX5

9.64e-0577107421525287
Pubmed

Sip1 regulates sequential fate decisions by feedback signaling from postmitotic neurons to progenitors.

POU3F2 TBR1 NEUROD6

1.20e-0431107319838179
Pubmed

Corticothalamic Projection Neuron Development beyond Subtype Specification: Fog2 and Intersectional Controls Regulate Intraclass Neuronal Diversity.

GATA2 NR2F2 TBR1

1.20e-0431107327321927
Pubmed

Single-cell transcriptomic analysis reveals diversity within mammalian spinal motor neurons.

MECOM POU3F1 NR2F2

1.32e-0432107336596814
Pubmed

Lengthening Neurogenic Period during Neocortical Development Causes a Hallmark of Neocortex Expansion.

POU3F2 TBR1

1.40e-046107232888487
Pubmed

Expression of a large family of POU-domain regulatory genes in mammalian brain development.

POU3F1 POU3F2

1.40e-04610722739723
Pubmed

L-type calcium channels play a critical role in maintaining lens transparency by regulating phosphorylation of aquaporin-0 and myosin light chain and expression of connexins.

CACNA1C MIP

1.40e-046107223734214
Pubmed

Sox12 deletion in the mouse reveals nonreciprocal redundancy with the related Sox4 and Sox11 transcription factors.

POU3F1 POU3F2

1.40e-046107218505825
Pubmed

Pharmacological Rescue of the Brain Cortex Phenotype of Tbx1 Mouse Mutants: Significance for 22q11.2 Deletion Syndrome.

TBR1 TBX1

1.40e-046107234552467
Pubmed

The Pou5f1/Pou3f-dependent but SoxB-independent regulation of conserved enhancer N2 initiates Sox2 expression during epiblast to neural plate stages in vertebrates.

POU3F1 POU3F2

1.40e-046107221185279
GeneFamilyBlood group antigens|CD molecules|Proteoglycans

HSPG2 CD44

3.42e-047742570
CoexpressionDESCARTES_FETAL_THYMUS_VASCULAR_ENDOTHELIAL_CELLS

COL15A1 MPDZ MECOM PKHD1L1 RNF220 CAVIN2

1.41e-051311046M40316
CoexpressionGSE13411_NAIVE_VS_MEMORY_BCELL_DN

FOXO3 MIA3 TNIP1 ATG2A MEA1 RNF220 CDK2AP1

1.44e-051981047M3246
ToppCell5'-Adult-LymphNode-Endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GATA2 MPDZ PKHD1L1 F8 NR2F2 BACE2 TBX1 CAVIN2

2.55e-081981068d7e15e61b6018e4c36461c9471ee29601929925c
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MPDZ PKHD1L1 F8 NR2F2 CATSPERB TBX1 CAVIN2

1.95e-0717310677dc988fc0ba29990567bf1bcdeb3faeeee507eb1
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D122|Adult / Lineage, Cell type, age group and donor

ATP13A4 CPAMD8 FAM184A MECOM MALRD1 USP54 SLC22A31

2.19e-0717610673fee8a367bb9755aca1b7fcc968b08e51b6e9436
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor_MEMP|lymph-node_spleen / Manually curated celltypes from each tissue

HSPG2 GATA2 MECOM MALRD1 CDK2AP1 CPXM1 CAVIN2

2.19e-07176106723a8ec42ebd42c539865a12d09773af90f3f8848
ToppCell5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS4 PKHD1L1 F8 CATSPERB BACE2 TBX1 CAVIN2

2.75e-071821067fd786c88826ad3d5cc5c3d80f8e392d6be1b5267
ToppCelldroplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 MECOM F8 NR2F2 TMCC2 BACE2 CAVIN2

2.85e-071831067709a486154b3157427deb3b8886b63ac39ea42dd
ToppCelldroplet-Liver-nan-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 MECOM F8 NR2F2 TMCC2 BACE2 CAVIN2

2.85e-071831067dc06f19f6f80f4c7f13f1f990c1fe0f91ba64ea7
ToppCell5'-Adult-Appendix-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS4 PKHD1L1 F8 CATSPERB BACE2 TBX1 CAVIN2

2.96e-071841067453295362888c9a59d0e73c7a5b15914c50ff591
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Adult / Lineage, Cell type, age group and donor

ATP13A4 CPAMD8 FAM184A MECOM MALRD1 USP54 SLC22A31

3.07e-071851067673f0c688ae6984bc8027df2da335787924f4137
ToppCellCOVID-19-Neuronal_cells-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

PKHD1L1 F8 NR2F2 CATSPERB BACE2 TBX1 CAVIN2

3.07e-0718510674a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCellCOVID-19-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

PKHD1L1 F8 NR2F2 CATSPERB BACE2 TBX1 CAVIN2

3.07e-07185106736ce23893915f5c380cca39b2c33a516edf31c3a
ToppCellEndothelial-endothelial_cell_of_lymph_vessel|World / Lineage, Cell type, age group and donor

PKHD1L1 F8 NR2F2 CATSPERB BACE2 TBX1 CAVIN2

3.42e-07188106780910dcbb51990f2baed240f319456c0d3fa2065
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel|Children_(3_yrs) / Lineage, Cell type, age group and donor

PKHD1L1 F8 NR2F2 CATSPERB BACE2 TBX1 CAVIN2

3.42e-071881067c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CPAMD8 PKHD1L1 F8 NR2F2 TBX1 CAVIN2 CFAP46

3.42e-071881067524a12f433c7b6f33fad36c0716afa06cd3235e9
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CPAMD8 PKHD1L1 F8 NR2F2 TBX1 CAVIN2 CFAP46

3.42e-071881067d2610b81b3c7f22977b5e2137b1f61410fc4ef16
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

MPDZ PKHD1L1 F8 NR2F2 CATSPERB BACE2 TBX1

3.42e-071881067aeecbc057dc823f8fcea8a98f18d213bacc7f4db
ToppCellEndothelial-endothelial_cell_of_artery|World / Lineage, Cell type, age group and donor

HSPG2 CPAMD8 GATA2 MECOM ITGB4 F8 TBX1

3.54e-071891067fdd89c71113ac99b7c800c6def8888e512ff1128
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ATP13A4 CPAMD8 FAM184A MECOM RNF220 KIAA1328 USP54

3.67e-0719010678aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 KIF26A MECOM F8 TMCC2 BACE2 CAVIN2

3.67e-071901067a08c5929b05a4969852e351a93c4e4deb4c8d5b6
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF26A GATA2 PKHD1L1 F8 BACE2 TBX1 CAVIN2

3.67e-07190106732400c62cb9de4c2b24af4206c21a0215ab12212
ToppCellnormal_Lung-Endothelial_cells-Lymphatic_ECs|normal_Lung / Location, Cell class and cell subclass

PKHD1L1 ITGB4 F8 NR2F2 BACE2 TBX1 CAVIN2

3.67e-0719010672185db6007404a2b22325f91460dd17635be9bba
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 KIF26A MECOM F8 TMCC2 BACE2 CAVIN2

3.67e-07190106725525fee1da8a808034d9c916159fd0b6b26bce8
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

ATP13A4 CPAMD8 FAM184A MECOM MALRD1 USP54 SLC22A31

3.80e-071911067d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor_Erythro-Mega|bone_marrow / Manually curated celltypes from each tissue

HSPG2 POLE2 GATA2 MECOM CDK2AP1 CPXM1 CAVIN2

3.94e-071921067cbc304c704e8524eee24a1619d0fbb2cf96c4976
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 KIF26A MECOM F8 TMCC2 BACE2 CAVIN2

4.08e-071931067d485634c564b268e344b6a2863c26f6adaec9e38
ToppCell356C-Endothelial_cells-Endothelial-A_(Artery)|356C / Donor, Lineage, Cell class and subclass (all cells)

HSPG2 COL15A1 ADAMTS4 KIF26A ITGB4 F8 CAVIN2

4.23e-0719410672e5b195e02dcd5e9432b9a98b22e0478e65b9ba2
ToppCellnucseq-Endothelial-Endothelial_Lymphatic-LEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PKHD1L1 F8 NR2F2 CATSPERB BACE2 TBX1 CAVIN2

4.23e-071941067f772a9f9ef8635aeaeb8b022dbb94e9672b36ead
ToppCellnucseq-Endothelial-Endothelial_Lymphatic-LEC-LEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PKHD1L1 F8 NR2F2 CATSPERB BACE2 TBX1 CAVIN2

4.23e-0719410673b73f2d305a7566f7ab567e5f18c82cd3d80e32c
ToppCell356C-Endothelial_cells-Endothelial-A_(Artery)-|356C / Donor, Lineage, Cell class and subclass (all cells)

HSPG2 COL15A1 ADAMTS4 KIF26A ITGB4 F8 CAVIN2

4.23e-071941067b6b5b0ab506b05a005ba8a05a3c7f4c725ba9200
ToppCellnucseq-Endothelial-Endothelial_Lymphatic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PKHD1L1 F8 NR2F2 CATSPERB BACE2 TBX1 CAVIN2

4.23e-0719410675d2b3ed5374e2ab10c1c7eb3a03139fc95036a48
ToppCellControl-Endothelial|Control / Disease state, Lineage and Cell class

ADAMTS4 GATA2 PKHD1L1 NR2F2 BACE2 TBX1 CAVIN2

4.23e-071941067485fe5538fabec457b9a51feb641f2a91cbf4e18
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HSPG2 COL15A1 ADAMTS4 PKHD1L1 F8 NR2F2 CAVIN2

4.85e-07198106768ee0baa2f5cf239f2356cc59fee9041a7732bba
ToppCellSkin-Mesangial|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.

SPEG MPDZ ARID5A NR2F2 TTBK1 ZIC5 CFAP46

5.01e-071991067bcb78838a91cc7828680fb413fbacdb091c5fac0
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 KIF26A GATA2 MECOM ITGB4 NR2F2 CAVIN2

5.01e-071991067a8f2eb00c3e4267a174bc9eff307dc2e5d18c76e
ToppCell10x5'v1-week_14-16-Endothelial-stroma-tip_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

HSPG2 COL15A1 ADAMTS4 MPDZ NR2F2 MMP15 TBX1

5.19e-07200106777ac1aa73c16a4f595ff01c6b4e171e0b8fed1e6
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Adult / Lineage, Cell type, age group and donor

ATP13A4 CPAMD8 FAM184A MECOM USP54 SLC22A31

2.61e-061631066e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)-|356C / Donor, Lineage, Cell class and subclass (all cells)

KIF26A GATA2 F8 NR2F2 TBX1 CAVIN2

2.90e-0616610665ba45407a47207ff01e4a3f9f5d91d8247fe9b6f
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_bronchial_vessel-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL15A1 KIF26A ITGB4 ARID5A RHPN1 RP1L1

2.90e-061661066a697460dfe72e08fbf7d8e734a16b7dd2c6d86f9
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)|356C / Donor, Lineage, Cell class and subclass (all cells)

KIF26A GATA2 F8 NR2F2 TBX1 CAVIN2

2.90e-0616610666bd5aa205b6e4b88ba9f8cd0999e2191d7d1d16c
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D122|Adult / Lineage, Cell type, age group and donor

CPAMD8 KIF26A SPEG GATA2 F8 TBX1

3.10e-0616810668c3e1e45b422813bcdfa4273b1167db649a312f5
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor_Erythro-Mega|lymph-node_spleen / Manually curated celltypes from each tissue

GATA2 MPDZ MECOM CDK2AP1 CPXM1 CAVIN2

3.44e-0617110663ecd0a074344179c57eb2d9a857ba594904d00fa
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MPDZ PKHD1L1 F8 NR2F2 TBX1 CAVIN2

4.33e-061781066ad3de3e03a401dac64431a541899445262246347
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GATA2 PKHD1L1 F8 NR2F2 TBX1 CAVIN2

4.47e-06179106640c65e8623547aeb80f9cd2366e29072467ce069
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-OMD+_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

HSPG2 CPAMD8 MARCHF10 GATA2 MECOM TBX1

4.47e-0617910668c9ed247e1c4d655b81ce2f24a9936a7cade718a
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKHD1L1 ITGB4 NR2F2 BACE2 TBX1 CAVIN2

4.77e-061811066cef034030e6b029a49ae56be37ea1fac1a5c350e
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 KIF26A GATA2 MECOM ITGB4 CAVIN2

4.92e-061821066d0e3663f7d39f22a3ebd7fde56ab3504773598f4
ToppCell5'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PKHD1L1 F8 NR2F2 BACE2 TBX1 CAVIN2

5.08e-0618310662d0d3b486498a7903fa9a1f48b189291da49c430
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADAMTS4 PKHD1L1 ITGB4 CATSPERB BACE2 TBX1

5.08e-061831066bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCellPBMC-Severe-Hematopoietic-HSPC-HSPC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HSPG2 GATA2 MPDZ MECOM MALRD1 CPXM1

5.24e-06184106651d0447699e3b8f01abbde83f26b748bc9f3c723
ToppCellPBMC-Severe-Hematopoietic-HSPC-HSPC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HSPG2 GATA2 MPDZ MECOM MALRD1 CPXM1

5.24e-061841066f7b0bb45a9055ab34e98b251217f6ec38c75ca22
ToppCellPBMC-Severe-Hematopoietic-HSPC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

HSPG2 GATA2 MPDZ MECOM MALRD1 CPXM1

5.24e-06184106626edbf84216538b80f1ffcc079ee6e385a71fbf9
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

ATP13A4 CPAMD8 FAM184A MECOM USP54 SLC22A31

5.41e-06185106698b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PKHD1L1 ITGB4 F8 NR2F2 TBX1 CAVIN2

5.41e-061851066f9f48251bc33eb6bf2cff580d1a3207d21450aa0
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ATP13A4 CPAMD8 FAM184A MECOM USP54 SLC22A31

5.57e-0618610662ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCell(8)_CD34_progenitor|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

HSPG2 GATA2 MPDZ MECOM CPXM1 CAVIN2

5.57e-061861066943c604a7cd873faf510096d094100512ba2d6bc
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HSPG2 ATP13A4 NOXA1 IRX1 USP54 SLC22A31

5.57e-0618610663aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCell3'_v3-blood-Hematopoietic_progenitors-Progenitor_Erythro-Mega|blood / Manually curated celltypes from each tissue

HSPG2 GATA2 MPDZ MECOM CDK2AP1 CPXM1

5.57e-06186106659c115bbbb4bca4ad80be1809d8a0422b8438ea3
ToppCell(8)_CD34_progenitor|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

HSPG2 GATA2 MPDZ MECOM CPXM1 CAVIN2

5.57e-061861066e69a986b8618effd61875fda528a2e44aab11868
ToppCellLV-10._Endothelium_II|World / Chamber and Cluster_Paper

HSPG2 GATA2 MECOM PKHD1L1 ITGB4 F8

5.75e-0618710667876dcb4800c2e54874df3d933efb79307a64a97
ToppCellEpithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|World / Lineage, Cell type, age group and donor

ATP13A4 CPAMD8 FAM184A MECOM USP54 SLC22A31

5.75e-06187106681cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-bladder_urothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS13 GATA2 SREBF1 MECOM BACE2 MMP15

5.75e-061871066aa336fb568a24e12c0454265ddd71ed10a6614cf
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D175|Adult / Lineage, Cell type, age group and donor

ADAMTS4 PKHD1L1 NR2F2 CATSPERB BACE2 TBX1

5.75e-0618710661e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCellControl-Endothelial-VE_Peribronchial|Endothelial / Disease state, Lineage and Cell class

HSPG2 COL15A1 ADAMTS4 AKNA MECOM BACE2

5.75e-0618710665429ae85942b8ec3895cceb63c663de3c24ca064
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 COL15A1 KIF26A MECOM ITGB4 CAVIN2

6.11e-061891066db09d591b885ce2bc9e353f08b6694e2192582e1
ToppCellCOVID-19-lung-Lymphatic_EC|lung / Disease (COVID-19 only), tissue and cell type

PKHD1L1 NR2F2 CATSPERB BACE2 TBX1 CAVIN2

6.11e-061891066c8db9aaf54ea3cc96c4a2f777c3389e0f31f67f3
ToppCellCOVID-19_Severe-HSPC|World / disease group, cell group and cell class

HSPG2 GATA2 MPDZ MECOM MALRD1 CPXM1

6.11e-061891066555c0b13f1508b9e3712b36d77144e73e828bc76
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GATA2 RSC1A1 PKHD1L1 ITGB4 TBX1 CAVIN2

6.11e-0618910660739baad9a7da511dd3d7249f84299aee88370a1
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PKHD1L1 ITGB4 F8 NR2F2 TBX1 CAVIN2

6.11e-06189106655a1776a4ce049959b3f13a43744c7314bc1f00a
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 COL15A1 GATA2 MECOM TBX1 CAVIN2

6.11e-061891066a34f008dfcee4012977bbc5b60de6f0329ca2f65
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PKHD1L1 ITGB4 NR2F2 CATSPERB BACE2 TBX1

6.30e-0619010666e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel|Adult / Lineage, Cell type, age group and donor

PKHD1L1 F8 NR2F2 CATSPERB BACE2 TBX1

6.30e-06190106691bf3b7e9148589757436a53a4f58e0ebfe54400
ToppCellIPF-Endothelial-Lymphatic|World / Disease state, Lineage and Cell class

PKHD1L1 NR2F2 CATSPERB BACE2 TBX1 CAVIN2

6.30e-061901066ac029e73da5995221c9b9af551d85e4b835e21d6
ToppCellwk_20-22-Endothelial-Lymph_endothelial-Intermediate_lymphatic_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PKHD1L1 ITGB4 F8 BACE2 TBX1 CAVIN2

6.30e-061901066103e78c2233c3ee0c215a9dafe70705477e9ee5e
ToppCell5'-Adult-LymphNode-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PKHD1L1 F8 NR2F2 BACE2 TBX1 CAVIN2

6.30e-0619010666b704deeb44e1ffa10e604d0e5612b022f6cd9a6
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ATP13A4 CPAMD8 FAM184A MECOM RNF220 USP54

6.49e-06191106634cc997e4e5c727495f321e6807a84aa124da486
ToppCell10x5'v1-week_12-13-Endothelial-stroma-tip_EC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

HSPG2 COL15A1 ADAMTS4 NR2F2 MMP15 TBX1

6.49e-061911066cf1a67b7c0d5c0dc5d4d59faf9d9b1a3a1fb00e0
ToppCellwk_15-18-Endothelial-Lymph_endothelial-Intermediate_lymphatic_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

GATA2 PKHD1L1 ITGB4 F8 TBX1 CAVIN2

6.49e-061911066d25ac3206fe205a100cfee26431ff32c14c1938f
ToppCellControl-Endothelial-VE_Venous|Control / Disease state, Lineage and Cell class

HSPG2 ADAMTS4 GATA2 PKHD1L1 NR2F2 CAVIN2

6.49e-061911066617546cf4883dedf3323e03a53ba5adec334cf8e
ToppCellIPF-Endothelial-Lymphatic|IPF / Disease state, Lineage and Cell class

PKHD1L1 NR2F2 CATSPERB BACE2 TBX1 CAVIN2

6.69e-0619210662496edd8f3a41146d418879de9ee2ccc7857431f
ToppCellControl-Endothelial-Lymphatic|World / Disease state, Lineage and Cell class

PKHD1L1 NR2F2 CATSPERB BACE2 TBX1 CAVIN2

6.69e-061921066f95fb188aa642f3d0618242a770e7c4b70544adb
ToppCellCOVID-19-lung-Lymphatic_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PKHD1L1 NR2F2 CATSPERB BACE2 TBX1 CAVIN2

6.69e-061921066cbe57cda44232b183821ac633b60a2668265e616
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 F8 NR2F2 TMCC2 BACE2 CAVIN2

6.69e-0619210662bfac6b3956265205ca47d06888851ed68b65999
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ATP13A4 FAM184A MECOM MALRD1 USP54 SLC22A31

6.69e-06192106629f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCelldroplet-Pancreas-Exocrine-18m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 COL15A1 ASF1B CDC20 TBX1 CAVIN2

6.69e-061921066a42aed9e563f5f4af029b8804c104f11ad227a8f
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 F8 NR2F2 TMCC2 BACE2 CAVIN2

6.69e-0619210665890076929598e88fe9d59a4e4e858b446746ce9
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 F8 NR2F2 TMCC2 BACE2 CAVIN2

6.69e-061921066d525f7f088a53110912600a7c9f6d33b9270d534
ToppCellCOPD-Endothelial-Lymphatic|World / Disease state, Lineage and Cell class

PKHD1L1 NR2F2 CATSPERB BACE2 TBX1 CAVIN2

6.89e-06193106625bdc557055b5bce6a21f8696b48e991c696b979
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 MECOM F8 NR2F2 TMCC2 CAVIN2

6.89e-061931066826b8dd801298b3e0cd76232feae5a14026b8806
ToppCellLAM-Endothelial-LymEndo|LAM / Condition, Lineage and Cell class

ADAMTS4 PKHD1L1 F8 NR2F2 TBX1 CAVIN2

6.89e-06193106668eadc91c2d89edd2412e86dfe134dd7c0ef6ee9
ToppCellCOPD-Endothelial-Lymphatic|COPD / Disease state, Lineage and Cell class

HSPG2 PKHD1L1 NR2F2 BACE2 TBX1 CAVIN2

6.89e-06193106618bcf08068a236c4575c7a07181ac893dfdcbeeb
ToppCelldroplet-Heart-HEART-1m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GATA2 PKHD1L1 ITGB4 NR2F2 BACE2 TBX1

6.89e-061931066d0a5f212f8e8a13dbbe3e41df92548ef82eef70b
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 F8 NR2F2 TMCC2 BACE2 CAVIN2

6.89e-0619310664a8c97ff2dffc5c06351d1cb107e21e58250aa55
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 MECOM F8 NR2F2 TMCC2 CAVIN2

6.89e-06193106687d3a577d37fb0cb4b6313c596310de452bc3872
ToppCellControl-Endothelial-Lymphatic|Control / Disease state, Lineage and Cell class

PKHD1L1 NR2F2 CATSPERB BACE2 TBX1 CAVIN2

6.89e-06193106664d19be73e5432d491436a01da5de5c926b615a9
ToppCellfacs-MAT-Fat-3m-Endothelial|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF26A GATA2 MECOM ITGB4 TBX1 CAVIN2

6.89e-061931066b32533afeff1905e188becaa09079e9699722e4b
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 F8 NR2F2 TMCC2 BACE2 CAVIN2

6.89e-061931066d5f6d6e2c36d4e80af4d39cdfc0b18df295a587b
ToppCellfacs-MAT-Fat-3m-Endothelial-nan|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF26A GATA2 MECOM ITGB4 TBX1 CAVIN2

6.89e-0619310662ff573ba2c74583ed1cb071a3bbc01bb71117e5f
ToppCellfacs-MAT-Fat-3m-Endothelial-endothelial_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF26A GATA2 MECOM ITGB4 TBX1 CAVIN2

6.89e-061931066e164f6403a8b541ced08a6feec915d2e855036ea
ToppCell3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 ACP5 GATA2 MECOM NR2F2 CAVIN2

6.89e-0619310660f2967afbbf4e538b63f985c0acc2e5d9aab7589
ToppCellFetal_29-31_weeks-Epithelial|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ATP13A4 CPAMD8 FAM184A MECOM USP54 SLC22A31

6.89e-061931066a0ca3231992f14abcf1a6129573bace320e89d2a
DiseaseMyelodysplasia

GATA2 MECOM

1.18e-0521022C0026985
Diseasedisease prognosis measurement

FOXO3 CCDC201

1.76e-0461022EFO_0007936
DiseaseLynch Syndrome

MLH3 CD44

4.19e-0491022C4552100
Diseasediastolic blood pressure, systolic blood pressure

CACNA1C BRPF3 SPEG MECOM RNF220 MALRD1 CDK2AP1 ZIC5 CCDC201

5.33e-046701029EFO_0006335, EFO_0006336
Diseasecongenital diaphragmatic hernia (implicated_via_orthology)

NR2F2 KIF7

7.64e-04121022DOID:3827 (implicated_via_orthology)
Diseaseextrapulmonary tuberculosis

FOXO3 CACNA1C

7.64e-04121022MONDO_0000368
Diseasemean platelet volume

DYRK1A MECOM STIL YIF1B TMCC2 PCDHGB4 TMEM131L CATSPERB ASF1A CAVIN2 FERMT3

8.08e-04102010211EFO_0004584
Diseaseresting heart rate

CACNA1C SPEG SREBF1 RNF220

1.81e-031491024EFO_0004351
DiseaseCraniofacial Abnormalities

HSPG2 GATA2 ZIC5 TBX1

2.14e-031561024C0376634
Diseasecitrulline measurement

MECOM RP1L1

2.16e-03201022EFO_0009777
DiseaseParkinson's disease (implicated_via_orthology)

FOXO3 ATP13A4 SSTR5 YIF1B

2.19e-031571024DOID:14330 (implicated_via_orthology)
DiseaseAntihypertensive use measurement

CACNA1C HSPG2 MECOM IRX1 ATP2B2

2.31e-032651025EFO_0009927
Diseasemyeloperoxidase (MPO)-DNA complex measurement

ATP13A4 CATSPERB

2.61e-03221022EFO_0011039
Diseaseotitis media (implicated_via_orthology)

MECOM TBX1

2.61e-03221022DOID:10754 (implicated_via_orthology)
Diseasefemale reproductive system disease

PPP1R17 GREB1

2.86e-03231022EFO_0009549
Diseasecongenital heart disease (is_implicated_in)

IRX1 TBX1

3.11e-03241022DOID:1682 (is_implicated_in)
Diseaseserum alanine aminotransferase measurement

FOXO3 DYRK1A AKNA RPH3A MMP25 CDK2AP1 RP1L1 PCDHGB4 MMP15

3.19e-038691029EFO_0004735
Diseaseneuroimaging measurement, brain volume measurement

FOXO3 KLF11 TMCC2 CATSPERB NEUROD6

3.20e-032861025EFO_0004346, EFO_0006930

Protein segments in the cluster

PeptideGeneStartEntry
MEPAAALHFSRPASL

BTN2A3P

1

Q96KV6
PALASPAGAANFLAM

BACE2

66

Q9Y5Z0
AHFLATAGPSPMAAG

ARID5A

536

Q03989
AGPAPSPMRAANRSH

CDC20

36

Q12834
PDMGFETALAPQHTS

CATSPERB

531

Q9H7T0
ALNSAFGLTPDHPLM

ATP13A4

96

Q4VNC1
PAGRHMFVFQADAPN

ASF1A

66

Q9Y294
MRPNAFHSPLDAGAT

CFAP46

811

Q8IYW2
HSSGMDAVFPANSDP

CPXM1

221

Q96SM3
LDGQRHFNSMSGPAT

ACOT9

416

Q9Y305
SFHLPQPSFRMVDSG

BRPF3

111

Q9ULD4
AAPLFMSNDLRHISP

GLA

291

P06280
MTNHPAPNLFGTPRD

POLE2

111

P56282
RLAPSFSFHAAGLQM

DYRK1A

16

Q13627
LGHCDFMNRPAPESL

DHX32

441

Q7L7V1
APSPATAQLAGHSMD

FAM184A

21

Q8NB25
MFQIDSGRNAPLHSP

ATP2B2

976

Q01814
RLSAQAHPAGKMAPN

ATG2A

401

Q2TAZ0
AGMNPARSFAPAILT

MIP

181

P30301
MALSPGANLVFHEDP

MROH7

1

Q68CQ1
MSLARQPSADGSDPH

R3HDM1

551

Q15032
QPSADGSDPHAAMFQ

R3HDM1

556

Q15032
PGANHDARSLIMDSP

NOXA1

226

Q86UR1
VPLSPATNMSAHFRG

HSPG2

4061

P98160
AAAGLHASPMSADRV

NR2F2

271

P24468
DPQRNALLHMFSGKP

FAM90A7

111

A6NKC0
GPDGSALFDMVPHAA

PCDHGB4

566

Q9UN71
SDGSLQHARPTPFFM

MECOM

811

Q03112
LGHSSAPNSIMRPFY

MMP25

241

Q9NPA2
AAAAAATYHMPPGVS

NKX2-4

86

Q9H2Z4
QAGPASDHPSLNAAM

GREB1

256

Q4ZG55
SDHPSLNAAMGPAVF

GREB1

261

Q4ZG55
AAPSRLFNMDCPNHG

L3MBTL2

521

Q969R5
SAEMLPPNFRSAAAG

PPFIA3

1146

O75145
GLEHSSNPNAIMAPF

MMP15

266

P51511
PASSPARHTYGTMNN

TMEM63C

756

Q9P1W3
SARLPANRPDMSSHG

FAM90A27P

221

A6NNH2
ANRPDMSSHGALQPA

FAM90A27P

226

A6NNH2
AAPRSFHPPAAMSER

FAM104A

56

Q969W3
FQCAHGRPSMLPLAD

MLH3

1391

Q9UHC1
FRNSFLMGPVTPAHA

KIR3DL3

76

Q8N743
APGPATASAAAAMRL

KIF7

391

Q2M1P5
PLMHPDAAAAAAAAA

POU3F1

21

Q03052
AGPHAADNPRFTDMI

LHX5

331

Q9H2C1
LPPAMGRTALFHHSG

KIF26A

1641

Q9ULI4
FRPQLHHSGDMVFTP

F8

856

P00451
RMDFAFPGSTNSLHR

ITGB4

1446

P16144
MADVAGPSRPSAAAF

KIAA1328

1

Q86T90
LGPAFDDSQPSLHEM

FAM131B

221

Q86XD5
AASGTHLPQMPAAAY

FOXB1

141

Q99853
HVAFRPPASVGMSLN

MEIS3P2

336

A8K0S8
PPRDHSLNASQGHFM

MALRD1

691

Q5VYJ5
SPFSAAALAGHMAPV

GATA2

426

P23769
PAGRHMFVFQADAPN

ASF1B

66

Q9NVP2
NHRTDLFKSFPGPMD

ADAMTS4

591

O75173
QGAAKPDAHFRTMPC

C2orf92

166

A0A1B0GVN3
GSPRPAHANMNANAA

CACNA1C

21

Q13936
TDFFNPISHPMGRGH

CD44

451

P16070
ARHFLESAAPLAMDP

CPAMD8

1296

Q8IZJ3
DNSHLRSMPASFLPP

SQLE

381

Q14534
MPAAALNAAGSVHSP

CDK2AP1

11

O14519
KPPGFQASLARDGHM

AKNA

841

Q7Z591
PATLSATFQGHPMND

GLMP

166

Q8WWB7
HPMNDPTRTFANGSL

GLMP

176

Q8WWB7
NPPASFMHSALRDDI

MARCHF10

471

Q8NA82
PTPHFNDGRAMAKSL

EFHB

451

Q8N7U6
MHTPDFAGPDDARAV

KLF11

1

O14901
GSPMPAHFSQDLASH

CCDC201

56

A0A1B0GTI1
FQHPGSDMRQEKPSS

CAVIN2

11

O95810
PALHLAALNMPFSGD

COL15A1

1216

P39059
MSSLPTSDGFNHPAR

RSC1A1

1

Q92681
MSAPAGSSHPAASAR

SEC24B

1

O95487
PPHRLAFSMGAGLFS

SLC22A31

211

A6NKX4
MARPRFGAPHASESC

PPP6R2

651

O75170
GATALNNHSSIPMDP

MEA1

121

Q16626
SANLPVMGHEKFPSD

FOXO3

596

O43524
EDRMSHPSGPYSQAS

RPH3A

346

Q9Y2J0
PNSAAAAARMAGANP

TBR1

566

Q16650
MSLHDLPARPTAFNR

TMCC2

136

O75069
KPMVDAQHFLPAGDS

TMEM131L

1336

A2VDJ0
LDGFSRDAKMHPTPA

SYNRG

176

Q9UMZ2
SVPAAPAAYHGRSML

SAMD7

131

Q7Z3H4
PLMGDDHPNASRDSV

MIA3

581

Q5JRA6
LNMRSFLGVGAPHAA

IRX1

386

P78414
NMIPAHDSPLAALAF

WIPI2

196

Q9Y4P8
MLNHSGVGAFRPFAS

RNF220

111

Q5VTB9
AAAAAHLPPSMGASN

POU3F2

171

P20265
ATPPAHRAAANGLMQ

SSTR5

346

P35346
LRENFSHAPSPDMSA

RHPN1

256

Q8TCX5
VAAQGRAGSPFHPAM

URB1

2181

O60287
RAGSPFHPAMEALSL

URB1

2186

O60287
FLHEATARLMAGASP

SREBF1

1036

P36956
PESSSHANAMALGPL

TNIP1

136

Q15025
RKDTPALHMSPFAAG

PPP1R17

116

O96001
PHDFVFSPHNSGRPM

STIL

571

Q15468
MHPAGLAAAAAGTPR

YIF1B

1

Q5BJH7
PTPHAAFLADPVSNM

YIF1B

66

Q5BJH7
RFPQAAPLAHEIMSG

TEX13D

151

A0A0J9YY54
MPVAAQQPASRSHGA

TTBK1

1166

Q5TCY1
MERDSHGNASPARTP

TMPRSS13

1

Q9BYE2
PPSAFAEMGSDHTQS

MPDZ

1301

O75970
DPRMARAASSEAAPH

SPEG

2101

Q15772
LPDLGSHAMTENFTP

RP1L1

1181

Q8IWN7
GRSKSFNNHRPMDPE

SRGAP2

926

O75044
GVPNAPFHTAREMAN

ACP5

36

P13686
ALFRGMPAHFSDSAQ

FERMT3

176

Q86UX7
FASAHNMAPRKPHAG

PKHD1L1

3581

Q86WI1
AADAAPGPSAAFRLM

GTF3C4

36

Q9UKN8
ENFPMLHNSAPAGET

ZNF121

46

P58317
NHRPGALPLMSAFAR

TBX1

306

O43435
ASLASDHPQAGPSLM

TRIM66

726

O15016
EAAKGFNPHPSRFMD

USP54

766

Q70EL1
RDLSATAPAAAMHGA

ZIC5

201

Q96T25
GQGAMFRLPTDSHFP

NEUROD6

301

Q96NK8