Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
MousePheno	abnormal sperm fibrous sheath morphology	TMEM232 CCDC38 LZTFL1	3.43e-05	32	28	3	MP:0030590
MousePheno	abnormal sperm principal piece morphology	TMEM232 CCDC38 LZTFL1	9.65e-05	45	28	3	MP:0009836
Domain	VWA	COL28A1 CFB	4.39e-03	56	33	2	PF00092
Domain	Ank_2	RAI14 ANK3 TRPC6	6.36e-03	215	33	3	PF12796
Domain	Ank	RAI14 ANK3 TRPC6	7.48e-03	228	33	3	PF00023
Domain	-	COL28A1 CFB	7.55e-03	74	33	2	3.40.50.410
Domain	-	COLGALT2 GALNT1	8.99e-03	81	33	2	3.90.550.10
Domain	VWFA	COL28A1 CFB	9.20e-03	82	33	2	PS50234
Domain	-	RAI14 ANK3 TRPC6	9.41e-03	248	33	3	1.25.40.20
Domain	VWA	COL28A1 CFB	9.64e-03	84	33	2	SM00327
Domain	ANK	RAI14 ANK3 TRPC6	9.72e-03	251	33	3	SM00248
Domain	ANK_REPEAT	RAI14 ANK3 TRPC6	9.93e-03	253	33	3	PS50088
Domain	Ankyrin_rpt-contain_dom	RAI14 ANK3 TRPC6	1.00e-02	254	33	3	IPR020683
Domain	ANK_REP_REGION	RAI14 ANK3 TRPC6	1.00e-02	254	33	3	PS50297
Domain	Nucleotide-diphossugar_trans	COLGALT2 GALNT1	1.05e-02	88	33	2	IPR029044
Domain	Ankyrin_rpt	RAI14 ANK3 TRPC6	1.09e-02	262	33	3	IPR002110
Domain	VWF_A	COL28A1 CFB	1.32e-02	99	33	2	IPR002035
Domain	Ion_trans_dom	TRPC6 SCN4A	1.72e-02	114	33	2	IPR005821
Domain	Ion_trans	TRPC6 SCN4A	1.72e-02	114	33	2	PF00520
Pubmed	HLA-association of serum levels of natural antibodies.	HSPA2 CFB	4.93e-05	10	37	2	19167759
Pubmed	QKI is a critical pre-mRNA alternative splicing regulator of cardiac myofibrillogenesis and contractile function.	RAI14 ANK3	2.07e-04	20	37	2	33397958
Pubmed	Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data.	TMEM232 SMG6	2.99e-04	24	37	2	19584346
Pubmed	Structure and evolution of the Smith-Magenis syndrome repeat gene clusters, SMS-REPs.	CCDC144CP CCDC144A	4.39e-04	29	37	2	11997339
Pubmed	Altered expression of genes involved in regulation of vitamin A metabolism, solute transportation, and cytoskeletal function in the androgen-insensitive tfm mouse testis.	RAI14 LZTFL1	5.35e-04	32	37	2	17332066
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	YEATS2 COLGALT2 ZNF227 GCC2 USP47	5.49e-04	638	37	5	31182584
Pubmed	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.	CUL5 RGS7 GCC2 ALPK2 TRPC6	7.61e-04	686	37	5	29987050
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	CUL5 RALGAPA1 YEATS2 RAI14 ANK3 GCC2 SMG6	8.65e-04	1489	37	7	28611215
Pubmed	FBXO42 facilitates Notch signaling activation and global chromatin relaxation by promoting K63-linked polyubiquitination of RBPJ.	YEATS2 USP47 POLR3C	9.76e-04	183	37	3	36129980
GeneFamily	Ankyrin repeat domain containing	RAI14 ANK3	2.89e-02	242	20	2	403
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPA2 TRPC6 SCN4A SULT1E1	1.21e-05	171	37	4	285533ca2a6a411773313166bee35542f34d1a3c
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RAI14 HSPA2 TRPC6 SULT1E1	1.71e-05	187	37	4	d52f7bc0afcdc366b20d199ab33c4ec60ed22a68
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RAI14 ANK3 HSPA2 TRPC6	1.79e-05	189	37	4	d0c7549be4f77520c23dddf4f94d0fcad0081e37
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RAI14 HSPA2 TRPC6 SULT1E1	1.82e-05	190	37	4	a7f6c38bbf451f166febb21e6719d4afced4035e
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RAI14 HSPA2 TRPC6 SULT1E1	1.86e-05	191	37	4	239c1e68eb1cbe3e137a99fbd6eeb8d64c919ffd
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RAI14 HSPA2 TRPC6 SULT1E1	1.90e-05	192	37	4	5995bae840c0b3f420288f557634d0ae9a12a6ae
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RAI14 HSPA2 TRPC6 SULT1E1	2.10e-05	197	37	4	15a08b04acb1cb7e84aeb072c650ce07374181f5
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RAI14 HSPA2 TRPC6 SULT1E1	2.10e-05	197	37	4	b7e399b8e1a1ffc2b359f14929f199b93d9bbcce
Disease	posterior urethral valve	ALPK2 SMG6	6.08e-04	29	37	2	MONDO_0019640
Disease	dehydroepiandrosterone sulphate measurement	CYP3A43 TRPC6	3.31e-03	68	37	2	EFO_0007001

Protein segments in the cluster

Peptide	Gene	Start	Entry
KAEQMEKKQHEEFDL	SMG6	816	Q86US8
HEQNIQELMKHFKKE	CEP128	711	Q6ZU80
KVSEDLNQAFKEMHK	CUL5	501	Q93034
QEEKQLKMDHTAFFK	ALPK2	1376	Q86TB3
HEQKQQMEDFLRKQK	ANKRD26P1	191	Q6NSI1
HEKQKFDMIKDQFLK	TENT2	446	Q6PIY7
LHEELQQDMQKFKNE	CCDC144CP	441	Q8IYA2
VIENMNKEKAFLFEK	RAI14	586	Q9P0K7
KAQDFMKKFTQVLED	PDS5B	541	Q9NTI5
FEEKFQKFLENEDMH	LRRC9	446	Q6ZRR7
KDNEQHVFKVKDMEN	CFB	446	P00751
QEQLHMAEKELEKKF	LZTFL1	251	Q9NQ48
KKMNDFHISDDEEKN	MAP9	71	Q49MG5
RNQMAEKDEYEHKQK	HSPA2	586	P54652
HKLKVQEEMLKEEFQ	GBP4	566	Q96PP9
DQFFRDKIMEKKQDH	ALAS2	146	P22557
DQEKMKEMFKINQFN	GALNT1	71	Q10472
KKNDPNFEIFHKEMN	COL28A1	936	Q2UY09
LKDKQKHRVDFFQQM	CYP3A43	261	Q9HB55
KDDFINKLKNSHEEM	GCC2	596	Q8IWJ2
LHEELQQDMQKFKNE	CCDC144B	491	Q3MJ40
QKDFMVLKTKDEHAQ	ANK3	2781	Q12955
FRDEKMKEKQRHQQE	CCDC38	496	Q502W7
LHEELQQDMQKFKNE	CCDC144A	491	A2RUR9
EDDVRFEHQFKKKLM	COLGALT2	436	Q8IYK4
FIFMQAEAQAKVDKK	RGS7	166	P49802
EEFQQMLEKFKKHQE	SCN4A	466	P35499
KQEDEKVVNMHPQDF	TFB2M	356	Q9H5Q4
IHQDKMNFIKEENLD	CCDC110	286	Q8TBZ0
EIEKHYQQNEDKMRK	C10orf67	151	Q8IYJ2
EEKEFVEKHFNDLNM	RALGAPA1	1731	Q6GYQ0
QKKHIEQKQVEDFAM	POLR3C	371	Q9BUI4
LNEKFDKHYEQQMKE	SULT1E1	271	P49888
EKNHFQEVMKKREEK	TMEM232	626	C9JQI7
QNIFDEMKKKFLQIE	USP47	21	Q96K76
DVKNNLQIHEDFMKK	ZNF227	196	Q86WZ6
HKKGFQEDAEMNKIN	TRPC6	791	Q9Y210
IKEQFALEMKNKEHE	YEATS2	46	Q9ULM3