Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainConA-like_dom

BTN2A2 CELSR3

7.02e-03219112IPR013320
PathwayWP_MECP2_AND_ASSOCIATED_RETT_SYNDROME

YBX1 CEBPD

3.70e-044692MM15949
Pubmed

Proteomic analysis reveals that MAEL, a component of nuage, interacts with stress granule proteins in cancer cells.

EIF4B YBX1

9.53e-061511224189637
Pubmed

Downregulation of HERC5 E3 ligase attenuates the ubiquitination of CtBP1 to inhibit apoptosis in colorectal cancer cells.

USP19 YBX1

6.02e-053711234147029
Pubmed

The N-terminal domain of the Schaaf-Yang syndrome protein MAGEL2 likely has a role in RNA metabolism.

EIF4B YBX1

9.34e-054611234265304
Pubmed

EIF3H Orchestrates Hippo Pathway-Mediated Oncogenesis via Catalytic Control of YAP Stability.

EIF4B YBX1

1.34e-045511232269044
Pubmed

Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells.

EIF4B YBX1

1.44e-045711217932509
Pubmed

The SARS-CoV-2 RNA interactome.

EIF4B YBX1

2.43e-047411233989516
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

UBN2 EIF4B YBX1 CEBPD

2.78e-04110311434189442
Cytoband3p21.31

USP19 CELSR3

2.55e-041001123p21.31
CytobandEnsembl 112 genes in cytogenetic band chr3p21

USP19 CELSR3

2.49e-03316112chr3p21
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-cortical_neurons_2|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

YBX1 SHB

5.34e-04142112435f39976841438690fcbf85bfa8e7f5b9e43916
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNJ9 CELSR3

6.11e-04152112b61d2f6ee819c8dd4b4b601a8bc8388b1983de58
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ZNF324B SHB

6.27e-04154112ba55a63cfa5e0fb9dfec794f80078a2f0d03d0ad
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CEBPD SHB

6.85e-041611124362fe0c151f49eae7372b9673bac64d980a8389
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma|TCGA-Brain / Sample_Type by Project: Shred V9

KCNJ9 CELSR3

6.85e-041611125f6b2d7f80a8ee16651e304481d2da3fae313824
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

UBN2 ZNF324B

7.28e-04166112c11dcf9705b85ac3da6ae86358f5ffd64ae8327e
ToppCellfacs-Marrow-Granulocytes-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPT1 CEBPD

7.37e-04167112528493896aebe7d03d4b6ad2341b12927859e2e4
ToppCellfacs-Marrow-Granulocytes-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPT1 CEBPD

7.37e-04167112a82e85caf79395baa48380786d9df32a86dfd1ce
ToppCell10x5'-lymph-node_spleen-Lymphocytic_B-ABC_aged-B_naive|lymph-node_spleen / Manually curated celltypes from each tissue

BTN2A2 YBX1

7.46e-04168112494d5a11154ff22fedb25f4036d730cef376da60
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

YBX1 CEBPD

8.09e-041751121c7725f917f3d6b9e0a31ede9524690f408a5ea1
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

UBN2 TRPT1

8.09e-04175112dbd9dac129fb6ae5f55e7b96d04b37585458dc4a
ToppCellfacs-Tongue-nan-24m-Epithelial-basal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

YBX1 CEBPD

8.36e-04178112c92d7493853a717e2e7a76526e4e803564d182b7
ToppCellBL-critical-LOC-Lymphoid-NKT|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EIF4B YBX1

8.64e-04181112e3add2412c9f8eddfb77e0fbcd66fe57b23ae513
ToppCell343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

UBN2 CEBPD

8.93e-041841122c2125b8030af83f7a6d59a7102d4de8e0ac1988
ToppCelldroplet-Tongue-nan-24m-Epithelial-basal_cell|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EIF4B CEBPD

9.22e-0418711213056622d9921ee0b03325701d94df82ffbaa5d4
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CEBPD SHB

9.22e-041871125917bdfe84cf5941e21b415aebbab3090cc5d576
ToppCellGlobus_pallidus-Neuronal|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

KCNJ9 CELSR3

9.52e-04190112416de85d8841dac883faa6f5339b2fb461a09e82
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CEBPD SHB

9.62e-041911121eef30384cb6721974f318daf0b8bdd25d1b8206
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBN2 CEBPD

9.72e-041921121304e69c92cef3bd8c82e3c035a7562f5440139a
ToppCellEntopeduncular-Neuronal|Entopeduncular / BrainAtlas - Mouse McCarroll V32

KCNJ9 CELSR3

9.72e-041921124c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCellCOVID-mDC2-|COVID / Condition, Cell_class and T cell subcluster

BTN2A2 CEBPD

1.01e-031961126d02a4c5c19be7e036150cf945585cf5a773bc87
ToppCellCOVID-mDC2|COVID / Condition, Cell_class and T cell subcluster

BTN2A2 CEBPD

1.01e-03196112bb13926bb664be917017edb0ce7f184abe31744b
ToppCelldroplet-Tongue-TONGUE-1m-Epithelial-basal_cell_of_epidermis|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EIF4B YBX1

1.01e-03196112d4df86ce289835e76763213641989fde77935a16
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CEBPD SHB

1.01e-03196112279f43deeba4528cd63f5217a8441b5452bf0b16
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_2|COVID-19_Mild / Disease condition and Cell class

EIF4B CEBPD

1.02e-03197112e844f660010d114d65bd814f3d3fccd8e4a6b8da
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CEBPD SHB

1.02e-03197112ec7b7cebf60beab1d6dbafb8d6bb832fd8380098
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CEBPD SHB

1.03e-03198112eaeb70c0f7f7ca21f7d5bc5ea6c7c1a49a293c45
ToppCellTransverse-T_cell-Th17|T_cell / Region, Cell class and subclass

YBX1 CEBPD

1.03e-03198112918068ffd682c896c11d576072bde270630539d9
ToppCellPBMC_fresh-frozen|World / Compartment, severity and other cell annotations on 10x 3' data (130k)

EIF4B YBX1

1.03e-03198112dcc223a0396b8b673e4ed8c6733ec6cd74e9a03a
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

YBX1 CEBPD

1.03e-031981126b18e18ed88b6043d6a18bd0f4264ec785781e57
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CEBPD SHB

1.03e-031981129ec0ed556860e5543d327f4bf2370efc571ad75e
ToppCellSmart-seq2-thymus_(Smart-seq2)-myeloid|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

YBX1 CEBPD

1.03e-031981122e470249edc7cf85bed550795ff84cbef22895c0
ToppCellPBMC|World / Compartment, Disease Groups and Clusters

EIF4B CEBPD

1.03e-0319811284f5b43dad0c57556171dbc0b799735654582ecf
ToppCellBrain_organoid-organoid_Velasco_nature-3_mon-Neuronal-Immature_CPNs|3_mon / Sample Type, Dataset, Time_group, and Cell type.

YBX1 SHB

1.03e-0319811232d58379a89be19b6b1a494bf033416546771c19
ToppCell(6)_Endothelial_cells-(6)_Endothelial-A_(Artery)|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

EIF4B CEBPD

1.04e-03199112fc68b42b25efc985d9204b1ab372fad10fddafe7
ToppCelllymphoid-T_cell-CD8+_Naive_T_cell|World / Lineage, cell class and subclass

EIF4B YBX1

1.04e-031991124de81f29c4d79868fd6254ceb81b4ddad22ae7d0
ToppCellmyeloid-Dendritic_cell|myeloid / Lineage, cell class and subclass

EIF4B YBX1

1.04e-03199112b81c0a40481f1006ac4aa8759af95448cb5fc2e6
ToppCellmyeloid-Dendritic_cell-Conventional_dendritic_cell|Dendritic_cell / Lineage, cell class and subclass

YBX1 CEBPD

1.04e-03199112688fc273c51a957e2e1f2c7d273376bd7971139d
ToppCell(0)_NK/T_cells-(0)_T_CD4|(0)_NK/T_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

EIF4B YBX1

1.04e-03199112a4bffbb9587829f0f52716d6939315a1aa1ae9b3
ToppCellmild-Lymphocytic|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

EIF4B YBX1

1.04e-0319911257a429b4c98decbd0bffb67733eaae1f907898a3
ToppCellmyeloid-Dendritic_cell-Conventional_dendritic_cell|myeloid / Lineage, cell class and subclass

EIF4B YBX1

1.04e-031991121e7ce1a1d6a7af18351d64b7a5334efa6dd9abc5
ToppCelllymphoid-T_cell-CD8+_Naive_T_cell|lymphoid / Lineage, cell class and subclass

EIF4B YBX1

1.04e-0319911222926327c93ede9f3408c99a0d56e373a33240ef
ToppCell367C-Endothelial_cells-Endothelial-A_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

EIF4B CEBPD

1.04e-0319911262936fb64b33f7ad671f9c610bed665f17d3145e
ToppCellSigmoid-T_cell-Th17|T_cell / Region, Cell class and subclass

YBX1 CEBPD

1.04e-03199112622f2ae4b1850b25f723a0385da49147dfec8285
ToppCell367C-Endothelial_cells-Endothelial-A_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

EIF4B CEBPD

1.04e-03199112f53e0e4c34e6aec81ab07593aa11e045ba04df06
ToppCelllymphoid-T_cell-CD8+_Naive_T_cell|T_cell / Lineage, cell class and subclass

EIF4B YBX1

1.04e-031991129ee40563e840a7fe97e7592539d42e19db438c64
ToppCellCOVID-19_Severe-Classical_Monocyte-cMono_3|COVID-19_Severe / Disease condition and Cell class

YBX1 CEBPD

1.04e-03199112ffb2ef9b7006cbed0f43637af040719b9776cbd5
ToppCell343B-Epithelial_cells-Epithelial-D_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

YBX1 CEBPD

1.05e-0320011205e61fa111f0f87f660cea2e69485fab553d3861
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Type_2_alveolar|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

YBX1 CEBPD

1.05e-03200112e6fea85df357731aad343e412672b5828403029f
ToppCellSepsis-ICU-NoSEP|Sepsis / Disease, condition lineage and cell class

EIF4B YBX1

1.05e-03200112173b74bd83c5018035ec73f33896d4058a2fff87
ToppCellcontrol-Myeloid-CD14_Monocytes_1|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

EIF4B YBX1

1.05e-032001126defe58adacae88a16c59506a2029d98173ada71
ToppCell343B-Epithelial_cells-Epithelial-D_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

YBX1 CEBPD

1.05e-0320011246d0ce6a747e7daa70ae27ea7fd519624a7e279b
ComputationalPhosphate metabolism.

YBX1 CEBPD

4.75e-045272MODULE_273
DrugCefsulodin sodium salt [52152-93-9]; Down 200; 7.2uM; PC3; HT_HG-U133A

BTN2A2 USP19 CELSR3

9.41e-051931134067_DN
DrugDantrolene sodium salt [14663-23-1]; Down 200; 11.8uM; PC3; HT_HG-U133A

BTN2A2 USP19 CELSR3

1.00e-041971133786_DN
DrugGalanthamine hydrobromide [1953-04-4]; Down 200; 10.8uM; HL60; HT_HG-U133A

USP19 ZNF324B SHB

1.00e-041971132131_DN
Drug(+,-)-Octopamine hydrochloride [770-05-8]; Up 200; 21uM; HL60; HT_HG-U133A

BTN2A2 SHB CELSR3

1.00e-041971133112_UP
Drugalpha-estradiol; Down 200; 0.01uM; MCF7; HG-U133A

BTN2A2 ZNF324B SHB

1.03e-04199113122_DN
Diseasehepatocyte growth factor-like protein measurement

USP19 CELSR3

7.22e-0538102EFO_0008154

Protein segments in the cluster

PeptideGeneStartEntry
GQEEPPRRRGRQRYV

KCNJ9

11

Q92806
GPDRGSPEYRQRRER

CEBPD

186

P49716
DRGSTLPRRQPPRDY

CELSR3

3116

Q9NYQ7
RRSVRRGPYRQRVPD

BTN2A2

346

Q8WVV5
RGPYRQRVPDNPERF

BTN2A2

351

Q8WVV5
YRRDDRGPPQRPKLN

EIF4B

321

P23588
QPPRPDYREQRRRGE

SHB

21

Q15464
DYREQRRRGERPSQP

SHB

26

Q15464
GRRAPRPREQDRDVQ

TRPT1

16

Q86TN4
YRRRNSPVERPPRAG

USP19

1211

O94966
RRREAEYPGPEREPE

UBN2

16

Q6ZU65
RRYPRRRGPPRNYQQ

YBX1

146

P67809
NYRRRRPENPKPQDG

YBX1

286

P67809
EYRVPGRQPRTPERQ

ZNF324B

181

Q6AW86