Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH8 DNAH9 DYNC1H1 DNAH17

4.32e-05182264GO:0008569
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAAF5 DNAH8 DNAH9 DYNC1H1 DNAH17

5.76e-05372265GO:0045505
GeneOntologyMolecularFunctionmethionine-tRNA ligase activity

MARS1 MARS2

1.28e-0422262GO:0004825
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH8 DNAH9 DYNC1H1 DNAH17

2.64e-04282264GO:0051959
GeneOntologyBiologicalProcesscell projection morphogenesis

DHX36 NES CLSTN3 LZTS3 UNC5B CNTN6 DIP2A PTPRF FGFR3 RASAL1 PLXNB3 VIL1 CNTN4 HDAC6 FN1 SEMA7A LAMB3 ATP9A CASK SPTBN4 KLF7 TNN NR2E1 MACF1 SMO PLEKHO1 MAPK8IP2 EPHA7 SOS1

2.96e-0882622529GO:0048858
GeneOntologyBiologicalProcesscell morphogenesis

DHX36 NES ZNF135 CLSTN3 LZTS3 UNC5B CNTN6 DIP2A PTPRF FGFR3 RASAL1 PLXNB3 SOX6 VIL1 CNTN4 HDAC6 FN1 SEMA7A LAMB3 ATP9A SLC1A3 CASK CDC42EP1 SPTBN4 SHROOM1 KLF7 TNN NR2E1 MACF1 SMO PLEKHO1 ZRANB1 MAPK8IP2 EPHA7 SOS1

8.81e-08119422535GO:0000902
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

DHX36 CLSTN3 LZTS3 UNC5B CNTN6 DIP2A PTPRF FGFR3 RASAL1 PLXNB3 VIL1 CNTN4 HDAC6 FN1 SEMA7A LAMB3 ATP9A CASK SPTBN4 KLF7 TNN NR2E1 MACF1 SMO PLEKHO1 MAPK8IP2 EPHA7 SOS1

9.11e-0881922528GO:0120039
GeneOntologyBiologicalProcessneuron projection morphogenesis

DHX36 CLSTN3 LZTS3 UNC5B CNTN6 DIP2A PTPRF FGFR3 RASAL1 PLXNB3 CNTN4 HDAC6 FN1 SEMA7A LAMB3 ATP9A CASK SPTBN4 KLF7 TNN NR2E1 MACF1 SMO MAPK8IP2 EPHA7 SOS1

7.47e-0780222526GO:0048812
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

DHX36 LZTS3 UNC5B CNTN6 DIP2A PTPRF FGFR3 PLXNB3 CNTN4 HDAC6 FN1 SEMA7A LAMB3 SLC1A3 CASK SPTBN4 KLF7 TNN NR2E1 MACF1 SMO MAPK8IP2 EPHA7 SOS1

2.45e-0674822524GO:0048667
GeneOntologyBiologicalProcessregulation of cell morphogenesis

DHX36 ZNF135 PTPRF RASAL1 PLXNB3 VIL1 HDAC6 FN1 CASK CDC42EP1 MACF1 PLEKHO1 ZRANB1

2.94e-0530222513GO:0022604
GeneOntologyBiologicalProcessmicrotubule-based movement

NEK10 NPHP4 IFT43 CFAP65 DNAAF5 DNAH8 DNAH9 DDX4 DYNC1H1 HDAC6 IFT57 DYNC2I1 MADD RGN NPHP3 DNAH17 CFAP46

3.14e-0549322517GO:0007018
GeneOntologyBiologicalProcesscilium movement

NEK10 NPHP4 CFAP65 DNAAF5 DNAH8 DNAH9 DDX4 DYNC1H1 RGN NPHP3 DNAH17 CFAP46

3.15e-0526122512GO:0003341
GeneOntologyBiologicalProcesscilium assembly

TBC1D19 IFT43 CFAP65 DNAAF5 CCDC66 WDR90 DNAH8 FOXJ1 HDAC6 IFT57 DYNC2I1 NPHP3 DNAH17 TRAPPC14 CFAP46

1.16e-0444422515GO:0060271
GeneOntologyBiologicalProcesspositive regulation of tubulin deacetylation

HDAC6 FNTA

1.18e-0422252GO:0090044
GeneOntologyBiologicalProcessmethionyl-tRNA aminoacylation

MARS1 MARS2

1.18e-0422252GO:0006431
GeneOntologyBiologicalProcessorganelle assembly

TBC1D19 KNTC1 SYNPO2L OBSCN IFT43 CFAP65 DNAAF5 CCDC66 MDN1 BRCA1 RRS1 RAB3GAP2 PACS2 WDR90 DNAH8 DYNC1H1 FOXJ1 VIL1 HDAC6 IFT57 DYNC2I1 NPHP3 DNAH17 CHEK2 BSCL2 TRAPPC14 CFAP46

1.24e-04113822527GO:0070925
GeneOntologyBiologicalProcessaxonogenesis

UNC5B CNTN6 FGFR3 PLXNB3 CNTN4 HDAC6 FN1 SEMA7A LAMB3 SPTBN4 KLF7 TNN NR2E1 MACF1 SMO EPHA7 SOS1

1.69e-0456622517GO:0007409
GeneOntologyCellularComponentouter dynein arm

DNAH8 DNAH9 DNAH17

2.59e-04122273GO:0036157
GeneOntologyCellularComponentdynein complex

DNAH8 DNAH9 DYNC1H1 DYNC2I1 DNAH17

2.96e-04542275GO:0030286
GeneOntologyCellularComponentRZZ complex

KNTC1 ZWILCH

3.50e-0432272GO:1990423
GeneOntologyCellularComponentmicrotubule associated complex

KATNAL2 DNAH8 DNAH9 DYNC1H1 HDAC6 FNTA DYNC2I1 DNAH17

3.87e-041612278GO:0005875
Domain-

MARS1 MARS2 IARS1 LARS2

5.69e-061121941.10.730.10
DomainATPase_dyneun-rel_AAA

MDN1 DNAH8 DNAH9 DYNC1H1

1.68e-05142194IPR011704
DomainAAA_5

MDN1 DNAH8 DNAH9 DYNC1H1

1.68e-05142194PF07728
DomaintRNAsynth_Ia_anticodon-bd

MARS1 MARS2 IARS1 LARS2

2.27e-05152194IPR009080
Domainaa-tRNA-synth_I_CS

MARS1 MARS2 IARS1 LARS2

4.95e-05182194IPR001412
Domainaa-tRNA-synth_Ia

MARS2 IARS1 LARS2

5.38e-0572193IPR002300
DomaintRNA-synt_1

MARS2 IARS1 LARS2

5.38e-0572193PF00133
DomainAA_TRNA_LIGASE_I

MARS1 MARS2 IARS1 LARS2

6.21e-05192194PS00178
DomainDHC_N1

DNAH8 DNAH9 DYNC1H1

8.53e-0582193PF08385
DomainDynein_heavy_dom-1

DNAH8 DNAH9 DYNC1H1

8.53e-0582193IPR013594
DomainSpectrin

SPTB DRP2 SPTBN4 MACF1

1.37e-04232194PF00435
DomainMFS_1_like

MFSD6 MFSD6L

1.37e-0422192PF12832
DomainMet-tRNA_synth

MARS1 MARS2

1.37e-0422192IPR014758
DomainMFS_assoc_dom

MFSD6 MFSD6L

1.37e-0422192IPR024989
DomainMetRS_core

MARS1 MARS2

1.37e-0422192IPR033911
DomainMethionyl/Leucyl_tRNA_Synth

MARS1 MARS2

1.37e-0422192IPR015413
DomaintRNA-synt_1g

MARS1 MARS2

1.37e-0422192PF09334
DomainSpectrin_repeat

SPTB DRP2 SPTBN4 MACF1

3.47e-04292194IPR002017
DomainSPEC

SPTB DRP2 SPTBN4 MACF1

5.11e-04322194SM00150
DomainSpectrin/alpha-actinin

SPTB DRP2 SPTBN4 MACF1

5.11e-04322194IPR018159
DomainDynein_heavy_chain_D4_dom

DNAH8 DNAH9 DYNC1H1

5.26e-04142193IPR024317
DomainDynein_HC_stalk

DNAH8 DNAH9 DYNC1H1

5.26e-04142193IPR024743
DomainDynein_heavy_dom-2

DNAH8 DNAH9 DYNC1H1

5.26e-04142193IPR013602
DomainDHC_N2

DNAH8 DNAH9 DYNC1H1

5.26e-04142193PF08393
DomainMT

DNAH8 DNAH9 DYNC1H1

5.26e-04142193PF12777
DomainAAA_8

DNAH8 DNAH9 DYNC1H1

5.26e-04142193PF12780
DomainDHC_fam

DNAH8 DNAH9 DYNC1H1

6.52e-04152193IPR026983
DomainDynein_heavy

DNAH8 DNAH9 DYNC1H1

6.52e-04152193PF03028
DomainDynein_heavy_dom

DNAH8 DNAH9 DYNC1H1

6.52e-04152193IPR004273
Domainfn3

OBSCN CNTN6 PTPRF CDON CNTN4 FN1 TNN EPHA7

6.63e-041622198PF00041
DomainFumarylacetoacetase_C-rel

FAHD2B FAHD2A

8.09e-0442192IPR011234
DomainFAA_hydrolase

FAHD2B FAHD2A

8.09e-0442192PF01557
Domain-

FAHD2B FAHD2A

8.09e-04421923.90.850.10
DomainFAM86

FAM86B2 EEF2KMT

8.09e-0442192IPR029426
DomainSpectrin_bsu

SPTB SPTBN4

8.09e-0442192IPR016343
DomainFAM86

FAM86B2 EEF2KMT

8.09e-0442192PF14904
DomainDefensin_propep

DEFA1 DEFA3

1.34e-0352192PF00879
DomainAlpha-defensin

DEFA1 DEFA3

1.34e-0352192IPR006081
DomainAlpha-defensin_pro

DEFA1 DEFA3

1.34e-0352192IPR016327
DomainDEFENSIN

DEFA1 DEFA3

1.34e-0352192PS00269
DomainDefensin_propep

DEFA1 DEFA3

1.34e-0352192IPR002366
DomainDefensin_1

DEFA1 DEFA3

1.34e-0352192PF00323
DomainDMAP_binding

DIP2A DIP2C

1.34e-0352192PF06464
DomainIG

TARM1 UNC5B OSCAR OBSCN CNTN6 PTPRF VSIG10L FGFR3 CDON CNTN4 SEMA7A LY9 FCAMR

1.46e-0342121913SM00409
DomainIg_sub

TARM1 UNC5B OSCAR OBSCN CNTN6 PTPRF VSIG10L FGFR3 CDON CNTN4 SEMA7A LY9 FCAMR

1.46e-0342121913IPR003599
DomainFN3

OBSCN CNTN6 PTPRF CDON CNTN4 FN1 TNN EPHA7

1.56e-031852198SM00060
DomainRossmann-like_a/b/a_fold

MARS1 MARS2 IARS1 LARS2

1.59e-03432194IPR014729
Domain-

MARS1 MARS2 IARS1 LARS2

1.59e-034321943.40.50.620
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

VWA5B2 PIEZO1 OBSCN EXTL3 NPHP4 GGA3 ITPR3 DIP2A MDN1 PTPRF SH3TC1 RRS1 RIPOR1 WDR90 GCN1 DYNC1H1 RASAL1 SEMA7A ATP13A1 POLE LAMB3 CHD8 LARS2 MADD ANO8 CNPPD1 MYOF TKFC KANK3 ZNF500 DIP2C HMGXB3 CEP170B ATPAF2

6.46e-1411052273435748872
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

CLSTN3 SPTB SRPK2 EXTL3 USP9Y DIP2A SACS DYNC1H1 PLXNB3 SOX6 CNTN4 BIN1 HDAC6 FN1 ATP13A1 POLR2C DYNC2I1 INTS8 WDR26 MADD RBCK1 CASK SPTBN4 CNPPD1 GMCL1 MACF1 MAPK8IP2 SOS1 SOS2

6.94e-0912852272935914814
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

TBC1D19 WWOX MARS1 SPTB OBSCN SRPK2 ZP3 DNAAF5 SH3TC1 TECPR2 OSBPL9 RIPOR1 PRUNE2 NPEPPS LARP1 DYNC2I1 INTS8 SFMBT2 ANO8 CASK SPTBN4 KLF7 SETBP1 DIP2C MACF1 BSCL2 MCTP2 ZRANB1 CEP170B SOS2

4.69e-0814892273028611215
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

SACS FGFR3 ADGRL2 DYNC1H1 ANK1 IARS1 LARP1 CHD8 LARS2 MYOF ZBED6 MACF1 HMGXB3 EIF3B

4.70e-083322271437433992
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

DHX36 NES ATP6AP1 LZTS3 MARS1 SPTB SRPK2 DIP2A HSPA12A SACS OSBPL9 PACS2 DYNC1H1 RASAL1 BIN1 FN1 NPEPPS IARS1 LARP1 ATP9A SLC1A3 MADD CASK SPTBN4 MTHFD1 MACF1 PLCH1 CEP170B MAPK8IP2

7.10e-0814312272937142655
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

LZTS3 BIN1 FAHD2B FN1 FAHD2A LARP1 DYNC2I1 ATP9A SLC1A3 CASK MTHFD1 TPH2 MACF1 CEP170B MAPK8IP2

1.82e-074302271532581705
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

KNTC1 NPHP4 SACS TXNDC16 PRUNE2 CNTN4 SEC16B ATP13A1 ANO8 MYOF NPHP3 DNAH17 DIP2C MACF1 PLCH1

1.02e-064932271515368895
Pubmed

A new member of the amphiphysin family connecting endocytosis and signal transduction pathways.

BIN1 SOS1 SOS2

1.09e-06422739182529
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

KATNAL2 ATP6AP1 MARS1 PIEZO1 SRPK2 CCNK MDN1 BRCA1 RRS1 DNAJC1 NOL8 NRDE2 TENT4B ATP13A1 POLR2C CHD8 ATP9A INTS8 CASK MYOF MTHFD1 ZBED6 EXD2 MACF1 EIF3B CEP170B STX6

1.95e-0614972272731527615
Pubmed

Skn-1a/Pou2f3 is required for the generation of Trpm5-expressing microvillous cells in the mouse main olfactory epithelium.

ITPR3 PLCB2 VIL1 TAS1R3

2.28e-0615227424428937
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TOB2 CLSTN3 GGA3 RRS1 RAB3GAP2 PACS2 RIPOR1 DYNC1H1 PLXNB3 ATP9A MADD MACF1 CEP170B

3.21e-064072271312693553
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

ATP6AP1 SRPK2 RRS1 FGFR3 DYNC1H1 HDAC6 IARS1 POLR2C LARP1 CASK MACF1 EPHA7

4.74e-063582271232460013
Pubmed

Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions.

BRCA1 FGFR3 HDAC6 FNTA CHEK2 SMO

7.27e-0671227628319113
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

ATP6AP1 EXTL3 NCAPG2 QSOX1 MDN1 PTPRF UBL3 ATP13A1 SLC26A2 NPEPPS PYROXD2 CHD8 INTS8 TGFBI MYOF TKFC MTHFD1 MACF1 BSCL2 CEP170B STX6

7.28e-0610612272133845483
Pubmed

Frontline Science: TNF-α and GM-CSF1 priming augments the role of SOS1/2 in driving activation of Ras, PI3K-γ, and neutrophil proinflammatory responses.

PLCB2 SOS1 SOS2

9.42e-067227330720883
Pubmed

Mammalian homologues of the Drosophila Son of sevenless gene map to murine chromosomes 17 and 12 and to human chromosomes 2 and 14, respectively.

SPTB SOS1 SOS2

9.42e-06722738276400
Pubmed

The folate metabolic enzyme ALDH1L1 is restricted to the midline of the early CNS, suggesting a role in human neural tube defects.

NES SLC1A3 MTHFD1

9.42e-067227317111379
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH8 DNAH9 DNAH17

9.42e-067227331178125
Pubmed

The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.

MARS1 CD109 MDN1 PTPRF BRCA1 RRS1 GCN1 SFXN4 MTHFD1 EXD2

9.71e-062622271036880596
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

EXTL3 BRCA1 FOXH1 FOXJ1 BIN1 HDAC6 SEMA7A PCDHA11 ZKSCAN3 SOS1 SOS2

1.21e-053292271117474147
Pubmed

Gastric tuft cells express DCLK1 and are expanded in hyperplasia.

PLCB2 VIL1 TAS1R3

1.50e-058227321688022
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

CLSTN3 MARS1 NCAPG2 ITPR3 DNAAF5 PTPRF SC5D RAB3GAP2 ADGRL2 GCN1 DYNC1H1 SFXN4 HECTD3 ATP13A1 IARS1 POLE ATP9A INTS8 EXD2

1.56e-059422271931073040
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

WWOX MARS1 UNC5B CCNK RAB3GAP2 ADGRL2 GCN1 DYNC1H1 HDAC6 IARS1 LARP1 XPNPEP1 CDC42EP1 MTHFD1 MACF1 PLCH1

1.92e-057082271639231216
Pubmed

Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2.

SPTB SPTBN4 SOS1 SOS2

2.01e-052522748493579
Pubmed

A catalogue of gene expression in the developing kidney.

CAPN5 TGFBI SMO

2.24e-059227314531791
Pubmed

MADD, a splice variant of IG20, is indispensable for MAPK activation and protection against apoptosis upon tumor necrosis factor-alpha treatment.

MADD SOS1 SOS2

2.24e-059227319289468
Pubmed

The Catalytically Inactive Mutation of the Ubiquitin-Conjugating Enzyme CDC34 Affects its Stability and Cell Proliferation.

MARS1 MDN1 GCN1 DYNC1H1 NPEPPS LARP1 LARS2 MTHFD1 EIF3B

2.83e-05237227929564676
Pubmed

Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.

MARS1 NCAPG2 DNAAF5 GCN1 IARS1 WDR26 SOS1 SOS2

2.92e-05183227823956138
Pubmed

Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice.

KATNAL2 CLSTN3 DNAH9 CHD8 LARS2

3.30e-0556227530104731
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

DHX36 CLSTN3 ZKSCAN8 PHF1 PAOX DIP2A HSPA12A CCDC66 WDR90 ZWILCH HDAC6 ATP13A1 IARS1 MADD CASK USP6 EXD2 EIF3B

4.17e-059252271828986522
Pubmed

Loss of cerebellar glutamate transporters EAAT4 and GLAST differentially affects the spontaneous firing pattern and survival of Purkinje cells.

SLC1A3 SLC1A6

4.24e-052227229741614
Pubmed

Neutrophil defensins enhance lung epithelial wound closure and mucin gene expression in vitro.

DEFA1 DEFA3

4.24e-052227212871849
Pubmed

Localization of ank1.5 in the sarcoplasmic reticulum precedes that of SERCA and RyR: relationship with the organization of obscurin in developing sarcomeres.

OBSCN ANK1

4.24e-052227219002483
Pubmed

Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair.

BRCA1 CHEK2

4.24e-052227214701743
Pubmed

[Prevalence of mutations BRCA1 5382insC, and CHEK2 1100delC in the population of Siberian region].

BRCA1 CHEK2

4.24e-052227222946335
Pubmed

Prevalence of Germline Mutations in Genes Engaged in DNA Damage Repair by Homologous Recombination in Patients with Triple-Negative and Hereditary Non-Triple-Negative Breast Cancers.

BRCA1 CHEK2

4.24e-052227226083025
Pubmed

Cloning, genomic organization and expression pattern of a novel Drosophila gene, the disco-interacting protein 2 (dip2), and its murine homolog.

DIP2A DIP2C

4.24e-052227212137943
Pubmed

Mutational characteristics of ANK1 and SPTB genes in hereditary spherocytosis.

SPTB ANK1

4.24e-052227226830532
Pubmed

Human Neutrophil Peptides 1-3--early markers in development of colorectal adenomas and carcinomas.

DEFA1 DEFA3

4.24e-052227218957723
Pubmed

Expression of Nestin associates with BRCA1 mutations, a basal-like phenotype and aggressive breast cancer.

NES BRCA1

4.24e-052227228439082
Pubmed

Salivary levels of HNP 1-3 are related to oral ulcer activity in Behçet's disease.

DEFA1 DEFA3

4.24e-052227222861387
Pubmed

A homologue of the Drosophila Son of sevenless gene maps to mouse chromosome 17.

SOS1 SOS2

4.24e-05222728307589
Pubmed

Checking in on Cds1 (Chk2): A checkpoint kinase and tumor suppressor.

BRCA1 CHEK2

4.24e-052227212111733
Pubmed

Differential roles of glial and neuronal glutamate transporters in Purkinje cell synapses.

SLC1A3 SLC1A6

4.24e-052227216177048
Pubmed

Defensins: antimicrobial and cytotoxic peptides of mammalian cells.

DEFA1 DEFA3

4.24e-05222728476558
Pubmed

Obscurin is a ligand for small ankyrin 1 in skeletal muscle.

OBSCN ANK1

4.24e-052227212631729
Pubmed

Novel protein RGPR-p117: its role as the regucalcin gene transcription factor.

SEC16B RGN

4.24e-052227219214710
Pubmed

Spectrin and ankyrin-based pathways: metazoan inventions for integrating cells into tissues.

SPTB ANK1

4.24e-052227211427698
Pubmed

Glutamate transporters GLAST and EAAT4 regulate postischemic Purkinje cell death: an in vivo study using a cardiac arrest model in mice lacking GLAST or EAAT4.

SLC1A3 SLC1A6

4.24e-052227216647773
Pubmed

Highly accurate two-gene classifier for differentiating gastrointestinal stromal tumors and leiomyosarcomas.

OBSCN PRUNE2

4.24e-052227217360660
Pubmed

Localization of human neutrophil peptide (HNP) and its messenger RNA in neutrophil series.

DEFA1 DEFA3

4.24e-05222728080882
Pubmed

Mapping the binding site on small ankyrin 1 for obscurin.

OBSCN ANK1

4.24e-052227217720975
Pubmed

Alpha-defensins secreted by dysplastic granulocytes inhibit the differentiation of monocytes in chronic myelomonocytic leukemia.

DEFA1 DEFA3

4.24e-052227219864642
Pubmed

A high-resolution genetic map of the nervous locus on mouse chromosome 8.

ANK1 FNTA

4.24e-05222729545640
Pubmed

Multidrug-resistant tuberculosis is associated with low plasma concentrations of human neutrophil peptides 1-3.

DEFA1 DEFA3

4.24e-052227221333105
Pubmed

Critical Requirement of SOS1 for Development of BCR/ABL-Driven Chronic Myelogenous Leukemia.

SOS1 SOS2

4.24e-052227236010887
Pubmed

A familial case of severe infantile nephronophthisis explained by oligogenic inheritance.

NPHP4 NPHP3

4.24e-052227228392475
Pubmed

BRCA1 is regulated by Chk2 in response to spindle damage.

BRCA1 CHEK2

4.24e-052227218804494
Pubmed

Alpha-defensin overexpression in patients with Bell's palsy and Ramsay Hunt syndrome.

DEFA1 DEFA3

4.24e-052227222737966
Pubmed

Midpregnancy vaginal fluid defensins, bacterial vaginosis, and risk of preterm delivery.

DEFA1 DEFA3

4.24e-052227218757648
Pubmed

Differential expression of murine CGI-105 gene in 3T3-L1 cells by adrenocorticotropic hormones.

FAHD2B FAHD2A

4.24e-052227215774318
Pubmed

Ankyrin binds to two distinct cytoplasmic domains of Na,K-ATPase alpha subunit.

SPTB ANK1

4.24e-05222728159688
Pubmed

alpha-Defensins 1, 2, and 3 are expressed by granulocytes in lymphoid tissues of HIV-1-seropositive and -seronegative individuals.

DEFA1 DEFA3

4.24e-052227216837860
Pubmed

Regulation of neovascularization by human neutrophil peptides (alpha-defensins): a link between inflammation and angiogenesis.

DEFA1 DEFA3

4.24e-052227215208269
Pubmed

Plasma human neutrophil proteins-1, -2, and -3 levels in patients with bladder cancer.

DEFA1 DEFA3

4.24e-052227223011762
Pubmed

Rotavirus enterotoxin NSP4 binds to the extracellular matrix proteins laminin-beta3 and fibronectin.

FN1 LAMB3

4.24e-052227215331737
Pubmed

Expression of α-defensin 1-3 in T cells from severe cutaneous drug-induced hypersensitivity reactions.

DEFA1 DEFA3

4.24e-052227220880148
Pubmed

Breast cancer sensitivity to neoadjuvant therapy in BRCA1 and CHEK2 mutation carriers and non-carriers.

BRCA1 CHEK2

4.24e-052227225414026
Pubmed

Increased alpha-defensins 1-3 production by dendritic cells in HIV-infected individuals is associated with slower disease progression.

DEFA1 DEFA3

4.24e-052227220195543
Pubmed

Effect of CHEK2 missense variant I157T on the risk of breast cancer in carriers of other CHEK2 or BRCA1 mutations.

BRCA1 CHEK2

4.24e-052227218930998
Pubmed

The involvement of ankyrin in the regulation of inositol 1,4,5-trisphosphate receptor-mediated internal Ca2+ release from Ca2+ storage vesicles in mouse T-lymphoma cells.

ITPR3 ANK1

4.24e-05222728385102
Pubmed

Unveiling the relationship between WWOX and BRCA1 in mammary tumorigenicity and in DNA repair pathway selection.

WWOX BRCA1

4.24e-052227238499540
Pubmed

[Clinical characteristics and genetic analysis of hereditary spherocytosis caused by mutations of ANK1 and SPTB genes].

SPTB ANK1

4.24e-052227231014431
Pubmed

Wwox-Brca1 interaction: role in DNA repair pathway choice.

WWOX BRCA1

4.24e-052227227869163
Pubmed

The putative role of human peritoneal adipocytes in the fight against bacteria: synthesis of the antimicrobial active peptide DEFA1-3.

DEFA1 DEFA3

4.24e-052227220424487
Pubmed

FN1 and TGFBI are key biomarkers of macrophage immune injury in diabetic kidney disease.

FN1 TGFBI

4.24e-052227237960829
Pubmed

Detection of colorectal disease by stool defensin assay: an exploratory study.

DEFA1 DEFA3

4.24e-052227217531545
Pubmed

Absence of both Sos-1 and Sos-2 in peripheral CD4(+) T cells leads to PI3K pathway activation and defects in migration.

SOS1 SOS2

4.24e-052227225973715
Pubmed

Low-Copy Number Polymorphism in DEFA1/DEFA3 Is Associated with Susceptibility to Hospital-Acquired Infections in Critically Ill Patients.

DEFA1 DEFA3

4.24e-052227229950924
Pubmed

Increased levels of human neutrophil alpha-defensins in chronic venous leg ulcers.

DEFA1 DEFA3

4.24e-052227218472248
Pubmed

Crystal structure of defensin HNP-3, an amphiphilic dimer: mechanisms of membrane permeabilization.

DEFA1 DEFA3

4.24e-05222722006422
Pubmed

Uterus hyperplasia and increased carcinogen-induced tumorigenesis in mice carrying a targeted mutation of the Chk2 phosphorylation site in Brca1.

BRCA1 CHEK2

4.24e-052227215485917
Pubmed

Identification of murine homologues of the Drosophila son of sevenless gene: potential activators of ras.

SOS1 SOS2

4.24e-05222721631150
Pubmed

Wwox Binding to the Murine Brca1-BRCT Domain Regulates Timing of Brip1 and CtIP Phospho-Protein Interactions with This Domain at DNA Double-Strand Breaks, and Repair Pathway Choice.

WWOX BRCA1

4.24e-052227235409089
Pubmed

Structural and functional versatility of the FHA domain in DNA-damage signaling by the tumor suppressor kinase Chk2.

BRCA1 CHEK2

4.24e-052227212049740
Pubmed

Structural insight into an ankyrin-sensitive lipid-binding site of erythroid beta-spectrin.

SPTB ANK1

4.24e-052227217520478
Pubmed

The capsule sensitizes Streptococcus pneumoniae to alpha-defensins human neutrophil proteins 1 to 3.

DEFA1 DEFA3

4.24e-052227218474654
Pubmed

SOS2 Comes to the Fore: Differential Functionalities in Physiology and Pathology.

SOS1 SOS2

4.24e-052227234205562
Pubmed

The Ras-specific exchange factors mouse Sos1 (mSos1) and mSos2 are regulated differently: mSos2 contains ubiquitination signals absent in mSos1.

SOS1 SOS2

4.24e-05222729372945
Pubmed

Increased levels of alpha-defensin (-1, -2 and -3) in type 1 diabetic patients with nephropathy.

DEFA1 DEFA3

4.24e-052227218003664
Pubmed

Human neutrophil peptides 1-3 as gastric cancer tissue markers measured by MALDI-imaging mass spectrometry: implications for infiltrated neutrophils as a tumor target.

DEFA1 DEFA3

4.24e-052227222297599
Pubmed

Chromosomal localization of two genes encoding human ras exchange factors: SOS1 maps to the 2p22-->p16 region and SOS2 to the 14q21-->q22 region of the human genome.

SOS1 SOS2

4.24e-05222728275713
Pubmed

Upregulated expression of human alpha-defensins 1, 2 and 3 in hypercholesteremia and its relationship with serum lipid levels.

DEFA1 DEFA3

4.24e-052227225300997
Pubmed

The CHK2-BRCA1 tumour suppressor pathway ensures chromosomal stability in human somatic cells.

BRCA1 CHEK2

4.24e-052227220364141
Pubmed

Homeobox genes and connective tissue patterning.

SPTB SOS1 SOS2

4.36e-051122737720577
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

DHX36 CLSTN3 ATP6AP1 PIEZO1 CD109 EXTL3 NCAPG2 SIAE BPNT2 PTPRF SC5D OSBPL9 TXNDC16 DNAJC1 CDON LAMB3 ATP9A MADD TGFBI MYOF BSCL2

4.50e-0512012272135696571
Pubmed

Chemosensory Cell-Derived Acetylcholine Drives Tracheal Mucociliary Clearance in Response to Virulence-Associated Formyl Peptides.

ITPR3 PLCB2 TAS1R3

5.78e-0512227332294408
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

MDN1 TECPR2 DNAH9 DYNC1H1 PRUNE2 MADD

6.44e-0510422769205841
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

MARS1 MDN1 PACS2 GCN1 DYNC1H1 NPEPPS IARS1 LARP1 CHD8 XPNPEP1 MYOF MTHFD1 MACF1 ZNF561 BSCL2 EIF3B

9.03e-058072271630575818
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH8 DYNC1H1 DNAH17

9.47e-051422739373155
InteractionTOP3B interactions

VWA5B2 PIEZO1 SPTB OBSCN EXTL3 NPHP4 GGA3 ITPR3 DIP2A MDN1 PTPRF SH3TC1 RRS1 RIPOR1 WDR90 GCN1 DYNC1H1 RASAL1 SEMA7A ATP13A1 IARS1 POLE LAMB3 CHD8 LARS2 MADD ANO8 CNPPD1 MYOF TKFC KANK3 ZNF500 DIP2C HMGXB3 CEP170B ATPAF2

4.45e-06147022136int:TOP3B
GeneFamilyAminoacyl tRNA synthetases, Class I

MARS1 MARS2 IARS1 LARS2

1.82e-05191554131
GeneFamilyFibronectin type III domain containing

OBSCN CNTN6 PTPRF CDON CNTN4 FN1 TNN EPHA7

7.23e-051601558555
GeneFamilyDyneins, axonemal

DNAH8 DNAH9 DNAH17

3.85e-04171553536
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

UNC5B OBSCN CNTN6 PTPRF FGFR3 CDON CNTN4

4.81e-041611557593
GeneFamilyFerlin family

MYOF FER1L4

1.07e-0361552828
GeneFamilyImmunoglobulin like domain containing

TARM1 OSCAR VSIG10L CDON CNTN4 SEMA7A LY9

1.40e-031931557594
GeneFamilyEF-hand domain containing|Spectrins

SPTB SPTBN4

1.49e-03715521113
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

SPTB OSBPL9 RASAL1 SPTBN4 PLEKHO1 SOS1 SOS2

2.02e-032061557682
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical|TCGA-Thryoid / Sample_Type by Project: Shred V9

GABRB2 UNC5B QSOX1 PTPRF FN1 SLC27A6 LAMB3 CDC42EP1 MCTP2 CEP170B

6.42e-0819422710b46c54802b8d1e0a0a17f9ed8e82eaf5e7f4849d
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIP2A MFSD14B TXNDC16 PACS2 PLXNB3 UBL3 ATP9A LARS2 CDC42EP1 EIF3B

8.54e-0820022710f0c338877e39226a90c4effe12f6501d33542a73
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VWA5B2 NEK10 CFAP65 HSPA12A NPAP1 WDR90 DNAH9 DYNC2I1 CFAP46

8.14e-07197227974a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellfacs-Brain_Non-Myeloid-Hippocampus|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIP2A MFSD14B TXNDC16 PACS2 PLXNB3 ATP9A LARS2 CDC42EP1 EIF3B

9.23e-072002279fc28f71ca1cd0fdae66009ae5afe175d22f2bd8c
ToppCellControl-Myeloid-Monocytes,_Macrophages-Mast-cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NEK10 PACS2 CACNA1I PLCB2 IFT57 EEF2KMT MTHFD1 MCTP2

1.64e-06159227881782e9e370558d61af5e0c760ac9759d69fb725
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR90 FGFR3 DRP2 DYNC2I1 SLC1A3 NR2E1 SMO

3.28e-061232277a45d6907c041ad3f3218cd46dccfc25d4bd961cb
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr-Polydendrocyte.Tnr.Tmem2_(Tmem2)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

BRCA1 ERP27 SLC49A3 UBL3 SLC27A6 SLC5A2

3.40e-06802276b95e4456adb7f7d42825351f010376c10bb35380
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

BRCA1 ERP27 SLC49A3 UBL3 SLC27A6 SLC5A2

3.40e-068022760d02b242164d27f38f70ed77b106612fc7a3abca
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_2|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

BRCA1 ERP27 SLC49A3 UBL3 SLC27A6 SLC5A2

3.40e-06802276313344cf7309bc17ca131b92a91b24489df577e2
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 MAB21L4 PTPRF PRUNE2 RFX6 ATP9A SPTBN4 MAPK8IP2

3.95e-061792278f2e8fc975c30992611630197b79daaeef7c4211d
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRB2 MYO7B OBSCN DNAH9 DRP2 ANK1 PLCH1 EPHA7

4.84e-0618422782cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRB2 MYO7B OBSCN DNAH9 DRP2 ANK1 PLCH1 EPHA7

4.84e-0618422782b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRB2 MYO7B OBSCN DNAH9 DRP2 ANK1 PLCH1 EPHA7

4.84e-061842278ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P1-Tnr|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

BRCA1 ERP27 SLC49A3 PLXNB3 UBL3 SLC27A6

4.84e-06852276159b3ac93490c3e4918ea61f8ede7add9e63ca40
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRB2 CLSTN3 SPTB PRUNE2 ANK1 SLC1A6 SPTBN4 MAPK8IP2

5.90e-061892278f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCellTCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Endometrioid-1|TCGA-Endometrium / Sample_Type by Project: Shred V9

UNC5B EXTL3 NCAPG2 BRCA1 ZWILCH XPNPEP1 MTHFD1 EPHA7

6.87e-061932278c2673d86f7d7b849788036032a93a6d136a70040
ToppCellwk_08-11-Epithelial-Airway_epithelial_progenitor-epi-prox-progenitor_intermediate_|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PTPRF ERP27 OSBPL9 FGFR3 FOXJ1 CPXM2 SLC27A6 LAMB3

8.28e-0619822781eb49b853a9e144e840c660060473fc7873f6478
ToppCellControl-Control-Lymphocyte-T/NK-NK_activated|Control / Disease, condition lineage and cell class

KATNAL2 ERP27 SOX6 DDX60 POLE LAMB3 SETBP1 MACF1

8.28e-06198227876d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCellNon-neuronal-Dividing-IPC-IPC-new|World / Primary Cells by Cluster

NES BRCA1 FGFR3 DNAJC1 CDON SLC1A3 MTHFD1 NR2E1

8.28e-06198227811d2d4d179bc31ef2897d7ceeaf9bed1b20cbdc0
ToppCellNon-neuronal-Dividing-IPC-IPC-new-9|World / Primary Cells by Cluster

NES BRCA1 FGFR3 DNAJC1 CDON SLC1A3 MTHFD1 NR2E1

8.28e-061982278c724ef958e14e17a7d8c02b9f842510c0780f635
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf-Oligodendrocyte.Tfr.Tmem2_(Tmem2)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PKDREJ BRCA1 ERP27 PLXNB3 UBL3 SLC27A6

1.47e-051032276287e945ef2f9646f1ff4a4c50fe6e8a5e7fe0d92
ToppCellCOVID-19_Severe-NK_CD56bright|COVID-19_Severe / disease group, cell group and cell class

ZNF135 DIP2A PYROXD2 RGN KANK3 CEP170B MYBL1

1.77e-0515922779e2067f0d76769717f7048dab505fadd36bbb83e
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular-6|TCGA-Stomach / Sample_Type by Project: Shred V9

ITPR3 WDR90 GCN1 ATP13A1 LARP1 FER1L4 CEP170B

1.77e-051592277655c0749c238bd68cb797adb83e25a23b8a3cc9d
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal-Intermediate|GW26 / Sample Type, Dataset, Time_group, and Cell type.

NEK10 CNTN6 SH3TC1 PACS2 CPXM2 TNN

2.03e-05109227648f675d36fece070410eb9cfe64805f4629e290f
ToppCellControl-APC-like-Monocytes|Control / group, cell type (main and fine annotations)

OSCAR EME2 TRABD2A DDX60 CHEK2 SMO LY9

2.07e-0516322774bc80a2c741d462724b6f3902377d48c57478932
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKDREJ TENT4B RFX6 SPTBN4 C1orf226 CEP170B SOS1

2.07e-051632277132aece9c79499b4bb3c2bde68d3d7202e1d8772
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-M/X_cells_(MLN/GHRL+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 MAB21L4 NPHP4 CFAP65 RFX6 AMER3 MAPK8IP2

2.33e-051662277f0912ce0df5ede3bc5e7c99ccfe4decc16c6064e
ToppCelldroplet-Heart-nan-24m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUP210L NCAPG2 BRCA1 ZWILCH POLE MADD SHROOM1

2.42e-051672277bad33497ceeab968a7eb8a48b921c6f936390743
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD109 VSIG10L ADGRL2 DNAH8 DDX60 TSPY26P CDC42EP1

2.52e-05168227755c9de7b3a1d6cf7b02b020ff92ab4ede8d195cc
ToppCellfacs-Marrow-T-cells-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP9Y SH3TC1 PACS2 FN1 CASK TGFBI MTMR4

2.72e-051702277a78d9789c3e7c84a36e1bd380192d7aba4a4d443
ToppCellfacs-Marrow-T-cells-3m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP9Y SH3TC1 PACS2 FN1 CASK TGFBI MTMR4

2.72e-051702277ff68600b945b3a5437b14e5411b3db800d0ccbe5
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

NES CD109 OBSCN ZP3 PAOX ADGRL2 ZWILCH

2.82e-0517122771ae4b6a25bc9c1065cf5d95998ebcc70aee21ab5
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-epithelial_progenitor_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GABRB2 MFSD6L VIL1 TRABD2A SLC26A2 TPH2 FCAMR

2.82e-051712277f2b31c97bbcc5164fc279ed0362007878887ad5e
ToppCell356C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|356C / Donor, Lineage, Cell class and subclass (all cells)

NES UNC5B CPT1C HFM1 ADGRL2 CST2 DIP2C

3.04e-05173227726e2e674f5d312fa8f61c11b553dc6101f063b16
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GABRB2 PTPRF FGFR3 VIL1 MARS2 SLC26A2 FCAMR

3.04e-05173227781c36b9fe02c59099f080b2db02f4eaf2783911f
ToppCell356C-Fibroblasts-Fibroblast-B_(Myofibroblast)|356C / Donor, Lineage, Cell class and subclass (all cells)

NES UNC5B CPT1C HFM1 ADGRL2 CST2 DIP2C

3.04e-05173227775e26a65071b0d2f30ed0b2aa9859c488f5cf362
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KNTC1 NCAPG2 BRCA1 TLCD3B KCTD19 POLE MYBL1

3.15e-05174227784da9faff088d05233183b425385beb054c92d1b
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial-N_cells_(NTS+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 MAB21L4 CFAP65 FOXH1 RFX6 SPTBN4 MAPK8IP2

3.27e-05175227797a58bc6ed2e8e359283d4214172c990c6e3755e
ToppCellP03-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MAB21L4 PTPRF AMHR2 FN1 LAMB3 MTHFD1 MACF1

3.39e-051762277f3a54038cde58326f1caed96ecca33c141bcc8b3
ToppCellAdult-Immune-enucleated_erythrocyte-D231|Adult / Lineage, Cell type, age group and donor

NUP210L SPTB PCDH12 ANK1 SEMA7A TPH2 LY9

3.51e-05177227715ee303fb6caea1fd645c3b777666196ce500a1c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYO7B PRUNE2 VIL1 CNTN4 SEC16B BIN1 EPHA7

3.78e-05179227758ae5a97fe2a14e1c6fdeb886397eb06fdaf0428
ToppCellfacs-Marrow-B-cells-18m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAOX DNAAF5 CAPN5 NOL8 SEMA7A SPTBN4 C1orf226

3.91e-0518022777368ab31c3273374ef260f0d710d4eea83cbc4a2
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXH1 SLC5A2 TGFBI FER1L4 CHEK2 PLCH1 CFAP46

4.05e-051812277c26d3cbbc592299786d79d1b15fc6bead2aafb9a
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES UNC5B FGFR3 ADGRL2 BIN1 SEMA7A KLF7

4.05e-051812277cd81bc307e2bc42c1e9b24d5645ab65fa18c6133
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

EXTL3 CPT1C PLCB2 POLR2C RBCK1 MCTP2 PLEKHO1

4.20e-051822277d486b0213bd3cf20965cb4e38e95981c4aaff259
ToppCelldroplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KNTC1 NCAPG2 DDX4 PLXNB3 PRUNE2 ZWILCH CHEK2

4.34e-051832277e91f00b75d43ee6293fdd4a129b789cd95f8d11a
ToppCellnormal-na-Lymphocytic-lymphocyte-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

BRCA1 ZWILCH PYROXD2 LARS2 UBOX5 ZNF557 EEF2KMT

4.50e-0518422772c286712428662bc4589dc5ac4011bf7ed403cb5
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-EECs|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GGA3 VSIG10L CCDC163 VIL1 AMHR2 RFX6 AMER3

4.65e-051852277d42f6722a6771752cd744146a09e2ead9b7252bc
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD109 SH3TC1 NRDE2 POLR2C TSPY26P KANK3 SMO

4.98e-0518722773699d5e71d779da922920aa3160895db187bf81b
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD109 SH3TC1 NRDE2 POLR2C TSPY26P KANK3 SMO

4.98e-051872277033ba52c0c2f9978784947098fa697368ae44834
ToppCellAdult-Mesenchymal-pericyte_cell|Adult / Lineage, Cell type, age group and donor

GABRB2 NES SPTB OBSCN ADGRL2 CNTN4 RGN

4.98e-05187227762759efb660179402fb574ce5701c89a2e17bcfe
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CNTN6 PTPRF OVCH2 UBL3 IFT57 LAMB3 MYOF

5.15e-051882277eea652bab161f19148a883e7e3fe2523b36b3cea
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA5B2 PTPRF PRUNE2 SEC16B RFX6 MADD SPTBN4

5.15e-051882277a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellMacrophages-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

MYO7B OSCAR TLR7 QSOX1 PLCB2 FN1 TGFBI

5.33e-051892277c05b4b565c0ce56dbb45fc9503654a2ec1a7e1e9
ToppCellBAL-Control-Lymphocyte-B-B_cell|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CLSTN3 ITPR3 SACS ANK1 SEMA7A ZBED6 LY9

5.51e-051902277da7341a8a423e5fe4d8e733d8e50c10a3318ac1c
ToppCellBAL-Control-Lymphocyte-B-B_cell-B_cell|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CLSTN3 ITPR3 SACS ANK1 SEMA7A ZBED6 LY9

5.51e-05190227742312f7d79fe889397d32910b625793e2535cc26
ToppCellBAL-Control-Lymphocyte-B-B_cell-B_cell-B_activate-7|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CLSTN3 ITPR3 SACS ANK1 SEMA7A ZBED6 LY9

5.51e-051902277682418a7a2096743112eae3790d40e7e600612c0
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

VWA5B2 MAB21L4 CFAP65 PRUNE2 RFX6 AMER3 MAPK8IP2

5.51e-051902277b1095b2a7467c152d16e4f19a9515aeb61fc9e3d
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NES UNC5B FGFR3 ADGRL2 BIN1 SEMA7A KLF7

5.69e-05191227740e617d3c93f03ae87baf6c0b2304b617f5fe782
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-NK|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NCAPG2 BRCA1 POLE LARP1 XPNPEP1 MACF1 MYBL1

5.88e-051922277930319cbd82b9e54864147ffcdc8bd0ea7b937be
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-NK-NK|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NCAPG2 BRCA1 POLE LARP1 XPNPEP1 MACF1 MYBL1

5.88e-051922277c7bcebcb88a25b2c97d798120efa9d5958e7f798
ToppCellfacs-Aorta-Heart-3m-Mesenchymal|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRF CDON FN1 LARS2 MYOF SMO EPHA7

5.88e-0519222770dc1f46e40346ed0b286e53b106a812441575100
ToppCelldroplet-Lung-nan-21m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES RIPOR1 FGFR3 ADGRL2 SEMA7A KLF7 KANK3

6.08e-051932277ffdcbc5caff7fd4cc2e83dd21a05d43b0593d542
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRB2 CLSTN3 SPTB PRUNE2 ANK1 SLC1A6 MAPK8IP2

6.08e-0519322775fb7808dd971c1cc64c2bd4f8f1de646fb2d77f4
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MAB21L4 USP9Y PHF1 TRABD2A CASK LY9 MYBL1

6.08e-051932277c3cffafc1d40c3d7cf81034d5c51f1c78f5eb0a9
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^medium_distal_(2)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PTPRF FOXJ1 AMHR2 KCTD19 LAMB3 RFX6 PLCH1

6.08e-0519322774b8202fcfe639a73f69a13f48fc3601ade256346
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_2|Thalamus / BrainAtlas - Mouse McCarroll V32

MYO7B PIEZO1 ITPR3 SH3TC1 FN1 MYOF

6.21e-05133227629b0c2c682c6b97823e7d8d8ba1f5114044b30ba
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^medium_distal_(2)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ITPR3 ERP27 FOXJ1 AMHR2 KCTD19 RFX6 PLCH1

6.28e-051942277413112ee8df7407fd418d57c2ff11aad3a6ec259
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KATNAL2 RIPOR1 DNAH8 ANK1 IFT57 SLC1A6 SETBP1

6.28e-05194227787604c93d20f9171e0a1279bdb6ad73fe5fed356
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

VWA5B2 MAB21L4 CFAP65 LAMB3 RFX6 AMER3 MCTP2

6.28e-051942277b30379f8dc41c86c746af9930541fbb4819d8fa0
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRF DYNC1H1 HDAC6 RFX6 MADD MACF1 MAPK8IP2

6.49e-0519522773e519cffa6144a62b06124642a14c9ff39b76554
ToppCell11.5-Distal-Epithelial-Neuroendocrine|Distal / Age, Tissue, Lineage and Cell class

VWA5B2 MFSD6L CFAP65 PRUNE2 RFX6 AMER3 MAPK8IP2

6.49e-051952277eda6ebe52c48bd6a9044886e75f584f46c2556e7
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

DNAH9 FOXJ1 ATP9A MACF1 PLCH1 MCTP2 CFAP46

6.70e-0519622776d02d494196e3f857d53eea46d9419690d43beca
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

DNAH9 FOXJ1 ATP9A MACF1 PLCH1 MCTP2 CFAP46

6.70e-051962277af4cdc61830685a888a1209826c23bcf54a43084
ToppCellAT2_cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

GABRB2 SIAE PTPRF ERP27 LAMB3 ATP9A CASK

6.92e-0519722775e0d222872a25bb9e9069d3dffda2844bb69874a
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TBC1D19 NEK10 USP9Y DIP2A CACNA1I MCTP2 MYBL1

6.92e-051972277e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellwk_20-22-Epithelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

NEK10 CFAP65 PTPRF DNAH9 FOXJ1 LAMB3 CFAP46

6.92e-051972277468071c1911cdf8e8806a78dbceb95379e28ae91
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NEK10 CFAP65 FOXH1 FOXJ1 TLCD3B PLCH1 CFAP46

6.92e-0519722776e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG|World / Primary Cells by Cluster

FGFR3 CDON FOXJ1 SOX6 SLC1A3 CDC42EP1 NR2E1

6.92e-05197227761749ccafeb938c310cff1de5ff924a1c794325a
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG-25|World / Primary Cells by Cluster

FGFR3 CDON FOXJ1 SOX6 SLC1A3 CDC42EP1 NR2E1

6.92e-0519722779d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

GABRB2 MFSD6L EME2 DDX4 RASAL1 ZNF114 ANK1

7.14e-05198227762059185afdf66126a6fbc899ce611c47e7a0feb
ToppCellLPS_only-Epithelial_airway-airway_epithelial-Ciliated|LPS_only / Treatment groups by lineage, cell group, cell type

KATNAL2 NEK10 CFAP65 DNAH9 FOXJ1 ZNF2 PLCH1

7.14e-0519822776d90b541fde357fbb40f8f7d4e8628a48b679718
ToppCellwk_08-11-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ITPR3 PTPRF FOXJ1 TRABD2A AMHR2 LAMB3 PLCH1

7.14e-05198227784697f316d9195ebe838cf57f4dbdd9feea43bec
ToppCellwk_08-11-Epithelial-Distal_epithelial_progenitor|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ITPR3 PTPRF FOXJ1 TRABD2A AMHR2 LAMB3 PLCH1

7.14e-051982277eda85a592527992b51a00f288cff0c3239c47e6f
ToppCellTransverse-T_cell-Tfh|T_cell / Region, Cell class and subclass

OBSCN NCAPG2 QSOX1 SH3TC1 CAPN5 KLF7 ZNF561

7.37e-05199227733ffea12b8228e0b5bd8942531c3b21d24224725
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MAB21L4 CNTN6 PTPRF SOX6 LAMB3 MYOF FCAMR

7.37e-051992277d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC5B DIP2A TXNDC16 PACS2 PLXNB3 BIN1 ATP9A

7.37e-05199227767d8c7e5356f5d409d4f98e8338cf6c499fd7aee
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

NES GBP6 PCDH12 ADGRL2 DYNC1H1 CDC42EP1 MACF1

7.60e-05200227779e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Macroglial-Astrocyte|3m / Sample Type, Dataset, Time_group, and Cell type.

NES FGFR3 DNAJC1 SOX6 SLC1A3 CDC42EP1 NR2E1

7.60e-05200227798d7f577b31a603bf835bf9b4ea31999445cf0e5
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Macroglial|3m / Sample Type, Dataset, Time_group, and Cell type.

NES FGFR3 DNAJC1 SOX6 SLC1A3 CDC42EP1 NR2E1

7.60e-05200227738b51f337e183011e3ff32997ec26d8a424c6b78
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

USP9Y PRUNE2 SETBP1 DIP2C PLCH1 EPHA7

9.27e-0514322767a7a9829ba63468c9745904d9e993590051207ab
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr-Polydendrocyte.Tnr.Pdgfa_(Pdgfa)|Hippocampus / BrainAtlas - Mouse McCarroll V32

MAB21L4 BRCA1 ERP27 PLXNB3 SLC27A6

1.02e-049122754d84281e8e3236c687b910cd76de836b70dafdb7
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P1-P1_2|Hippocampus / BrainAtlas - Mouse McCarroll V32

MAB21L4 BRCA1 ERP27 PLXNB3 SLC27A6

1.02e-0491227583564e9e4122c176a28c30b0c2546c82185ddaa6
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr|Hippocampus / BrainAtlas - Mouse McCarroll V32

MAB21L4 BRCA1 ERP27 PLXNB3 SLC27A6

1.02e-04912275ff6022b23e9bd8af24bcb658ae2b48eae6bf1e28
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF135 BRCA1 ERP27 SFXN4 SFMBT2 TKFC

1.30e-041522276aa88084ba1851d879ece82baa516f6b46cbd2eb8
ToppCellClub_cells-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

MAB21L4 MFSD6L ERP27 PYROXD2 SETBP1 SMO

1.34e-04153227677030b0e033f3635b1bbe7552a28c074ea7bb106
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA5B2 NEK10 DRP2 KCTD19 SLC5A2 TPH2

1.44e-0415522768fdda4e3657ac56188ae88ed3caf145f4d9d1567
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NEK10 SACS DNAH8 FOXJ1 BIN1 SETBP1

1.49e-041562276a5930b455e5c8586c43c50106ab4d8a1e5e9e3d6
ToppCell356C-Fibroblasts-Fibroblast-B_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

UNC5B HFM1 ZNF557 CST2 DIP2C MCTP2

1.55e-041572276f6210be2362d833c6d869ff921188bfc85dda11d
ToppCell356C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

UNC5B HFM1 ZNF557 CST2 DIP2C MCTP2

1.55e-04157227643a6b423fd70479822a564ff4225a1e4951ae5ed
Drugxenognosin B

WWOX DEFA1 DEFA3

3.78e-0642253CID005280551
DrugFlecainide acetate [54143-56-5]; Down 200; 8.4uM; MCF7; HT_HG-U133A

TBC1D19 MAB21L4 EXTL3 GGA3 RIPOR1 FGFR3 CDON BIN1 TRAPPC14 PLCH1 CEP170B

4.50e-06197225113937_DN
DiseaseColorectal Carcinoma

CLSTN3 CD109 OBSCN SH3TC1 SACS NPAP1 FGFR3 FOXH1 DNAH8 CNTN4 FN1 ZNF560 POLE LAMB3 CNPPD1 SETBP1 ZKSCAN3 CHEK2 DIP2C EPHA7

3.36e-0770221920C0009402
DiseaseBipolar Disorder

GABRB2 SRPK2 CNTN6 BRD1 DNAH8 CNTN4 LARS2 SLC1A3 SLC1A6 MTHFD1 NR2E1 TPH2 HTR3B PLEKHO1

1.48e-0547721914C0005586
DiseaseIntellectual Disability

GABRB2 PCDH12 BRCA1 SC5D SACS PACS2 DYNC1H1 CHD8 WDR26 KLF7 SETBP1 MACF1

1.41e-0444721912C3714756
DiseaseCiliopathies

GDF1 NPHP4 IFT43 FOXH1 DNAH8 NPHP3

1.76e-041102196C4277690
DiseasePolydactyly

IFT43 SC5D FGFR3 DYNC2I1 NPHP3 SMO

2.46e-041172196C0152427
Diseasespinocerebellar ataxia type 5 (implicated_via_orthology)

SPTB SPTBN4

3.26e-0442192DOID:0050882 (implicated_via_orthology)
Diseasehereditary spherocytosis (is_implicated_in)

SPTB ANK1

5.40e-0452192DOID:12971 (is_implicated_in)
Diseasearecaidine measurement

PYROXD2 MYOF

5.40e-0452192EFO_0801112
DiseaseHereditary spherocytosis

SPTB ANK1

5.40e-0452192cv:C0037889
DiseaseAnemia, hereditary spherocytic hemolytic

SPTB ANK1

5.40e-0452192C0221409
Diseaseglucose metabolism measurement, age-related hearing impairment

WWOX ATP9A ZNF557 EPHA7

6.05e-04522194EFO_0005782, EFO_0009367
Diseasemonoclonal gammopathy

HFM1 CNTN4 SFMBT2 SETBP1

6.50e-04532194EFO_0000203
Diseasestroke

PTPRF SFXN4 MARS2 C4orf54 TGFBI EPHA7

7.43e-041442196EFO_0000712
Diseasenephronophthisis (is_implicated_in)

NPHP4 NPHP3

8.07e-0462192DOID:12712 (is_implicated_in)
Diseaseepisodic ataxia type 6 (implicated_via_orthology)

SLC1A3 SLC1A6

8.07e-0462192DOID:0050994 (implicated_via_orthology)
Diseasecognitive function measurement

GABRB2 KNTC1 WWOX NUP210L PIEZO1 SRPK2 ZP3 CCDC66 PTPRF CACNA1I SLC49A3 FOXH1 CNTN4 SEC16B CXorf38 PYROXD2 RFX6 TGFBI EXD2 SETBP1 EPHA7 SOS1

1.07e-03143421922EFO_0008354
Diseaselimb-girdle muscular dystrophy (implicated_via_orthology)

MYOF FER1L4

1.12e-0372192DOID:11724 (implicated_via_orthology)
Diseaseaspartate aminotransferase measurement

PIEZO1 OBSCN HSPA12A BRCA1 SH3TC1 GCN1 SOX6 BIN1 SLC26A2 PYROXD2 MADD NPHP3 CHEK2 HMGXB3 SOS1 SOS2

1.25e-0390421916EFO_0004736
DiseaseHereditary spherocytosis

SPTB ANK1

1.49e-0382192C0037889
DiseaseMicrocephaly

PCDH12 DYNC1H1 IARS1 CASK

1.57e-03672194C0025958
DiseaseNephronophthisis

NPHP4 NPHP3

1.91e-0392192cv:C0687120
DiseaseKartagener Syndrome

DNAAF5 DNAH9 FOXJ1

2.22e-03352193C0022521
DiseaseCiliary Dyskinesia, Primary, 1, With Or Without Situs Inversus

DNAAF5 DNAH9 FOXJ1

2.22e-03352193C4551906
DiseasePolynesian Bronchiectasis

DNAAF5 DNAH9 FOXJ1

2.22e-03352193C4317124
Diseasesensory perception of sweet taste

GABRB2 PTPRF UBL3 DIP2C

3.29e-03822194GO_0050916
DiseaseRenal dysplasia and retinal aplasia (disorder)

NPHP4 NPHP3

3.45e-03122192C0403553
DiseaseAnorectal Malformations

SOX6 RFX6 CASK

3.49e-03412193C3495676
DiseaseCharcot-Marie-Tooth disease

MARS1 DYNC1H1 DRP2

3.74e-03422193cv:C0007959
DiseaseNephronophthisis

NPHP4 NPHP3

4.05e-03132192C0687120
Diseaseneurodegenerative disease (implicated_via_orthology)

GGA3 DYNC1H1 MARS2 SLC1A3 SLC1A6

4.63e-031452195DOID:1289 (implicated_via_orthology)
Disease1-methylurate measurement

PTPRF CNTN4

4.71e-03142192EFO_0021173
DiseaseHereditary Breast and Ovarian Cancer Syndrome

BRCA1 CHEK2

4.71e-03142192C0677776
DiseaseColorectal Neoplasms

CD109 SH3TC1 FGFR3 POLE CNPPD1 ZKSCAN3 CHEK2

4.81e-032772197C0009404
DiseasePrimary Ciliary Dyskinesia

DNAAF5 DNAH9 FOXJ1

5.14e-03472193C4551720
DiseaseNeurodevelopmental Disorders

GABRB2 KATNAL2 CASK SETBP1

5.15e-03932194C1535926
DiseaseSitus ambiguus

GDF1 DNAH9

5.40e-03152192C0266642
DiseaseAlobar Holoprosencephaly

FOXH1 CDON

5.40e-03152192C0431363
Diseasehemoglobin A1 measurement

PIEZO1 SPTB MFSD14B SOX6 ANK1 LARP1 WDR26 MADD MACF1 SOS2

5.74e-0352021910EFO_0007629
Diseaseinsomnia measurement

MFSD6 ITPR3 PHF1 WDR90 IFT57 TGFBI KLF7 PLCH1 EPHA7

6.11e-034432199EFO_0007876
DiseaseTetralogy of Fallot

GDF1 FOXH1

6.14e-03162192C0039685
DiseaseLobar Holoprosencephaly

FOXH1 CDON

6.14e-03162192C0431362
DiseaseSemilobar Holoprosencephaly

FOXH1 CDON

6.14e-03162192C0751617
DiseaseSchizophrenia

GABRB2 CFAP65 HSPA12A BRCA1 BRD1 LARS2 SLC1A3 SLC1A6 CNPPD1 MTHFD1 NR2E1 TPH2 HTR3B MCTP2

6.50e-0388321914C0036341
DiseaseAdenoid Cystic Carcinoma

CNTN6 BRCA1 BRD1 MYBL1

6.64e-031002194C0010606
DiseaseHoloprosencephaly

FOXH1 CDON

6.93e-03172192C0079541
DiseaseCharcot-Marie-Tooth disease type 2

MARS1 DYNC1H1

6.93e-03172192cv:C0270914

Protein segments in the cluster

PeptideGeneStartEntry
EAWASLPAEVLDSLV

TGFBI

146

Q15582
AWASVEDQPLQLSTE

AMER3

766

Q8N944
DAAASVLEPLKVVWA

BRD1

921

O95696
SEIDIWFPVVDQLEV

CHD8

1606

Q9HCK8
DTQDDPQAIIIWDIL

EIF3B

396

P55884
ETCDEPLWNIQATIE

CLSTN3

271

Q9BQT9
TDAQQDVPAWLEEIA

DDX4

661

Q9NQI0
LAISVALQWLDPSED

C2orf80

46

Q0P641
TWEPEENILDSRLIA

CBX6

41

O95503
SAIWAPDIIINEFVD

HTR3B

111

O95264
WNEVAVLDAIPLAAT

ANK1

1541

P16157
SSWVQIPEAALLVLA

ATP13A1

91

Q9HD20
TLSLQWEPEIIAVAV

CCNK

196

O75909
ECNWSDPLVELQTLT

CFAP46

926

Q8IYW2
LVITWETVPEELQNG

CNTN4

716

Q8IWV2
DTVDNLLRPEALESW

ADGRL2

611

O95490
WVDVVIDDRLPTVNN

CAPN5

131

O15484
ETKVADWLVQNDPSL

CEP170B

311

Q9Y4F5
NFIPEVWAEVSEKAL

CHEK2

446

O96017
STAVTPAVLWEESEI

CCDC163

61

A0A0D9SF12
QAPEWTEEDLSQLTR

DNAJC1

326

Q96KC8
NTPTSDELWALAVQE

AMHR2

446

Q16671
WLSPEAAIVSVVVLE

ANO8

836

Q9HCE9
QTWASPAEVVDLTLD

C18orf25

381

Q96B23
IAIPEWFLSENATVA

CPXM2

481

Q8N436
ARIIEQDAVVPSEWL

GMCL1

346

Q96IK5
SDIVSDSPVWQDQIL

CHM

66

P24386
IDSWINLSRVDPDAE

RASAL1

101

O95294
RLDVPVWDVEATLNF

QSOX1

516

O00391
WVVSSLENLPEALTD

RFX6

356

Q8HWS3
DIVNDITAEHISIWP

INTS8

786

Q75QN2
TWIQSTNVPIDIEEE

ITPR3

396

Q14573
PSLVTEDNLLWLAET

KCTD19

186

Q17RG1
VWVSLLDANDNAPEV

PCDH12

551

Q9NPG4
WTLPNDTEENTELVS

OSBPL9

466

Q96SU4
NRIESVIKELWPSAD

TENT4B

146

Q8NDF8
QVPVLDTEDAWLSVE

RAB3GAP2

1121

Q9H2M9
WVDAEALLIEEPEAT

MAB21L4

86

Q08AI8
WVEILDTNDNSPEVA

PCDHA11

336

Q9Y5I1
LEEAVELVCTAPQWV

CASK

906

O14936
SASLPDLDSENWIEV

LARP1

546

Q6PKG0
LDSPRVTVAQLDWDV

FAM86B2

216

P0C5J1
PETLSDALRQWFELV

MDN1

5576

Q9NU22
PDDVWLVDLDSNRVI

MADD

391

Q8WXG6
VWDEIVVLPIQSLDQ

MCTP2

241

Q6DN12
SPSALIQELEERLWE

LZTS3

316

O60299
SCVPEEVIWEVLSAI

MAGEC3

561

Q8TD91
VPSEALAIAVATEWD

ATPAF2

81

Q8N5M1
NFWAVDVSLIPAEAL

FOXH1

106

O75593
PTQDIRLWVSVEDAQ

RBCK1

51

Q9BYM8
PSDQRIDVELWAEQA

CFAP65

1206

Q6ZU64
EQTLSPLWDELLVFE

FER1L4

801

A9Z1Z3
EWTVVFDLSAVEPAE

GDF1

126

P27539
LSEDADSPWLLSNLV

MAPK8IP2

341

Q13387
VLLEEDRLAAEPSWN

DYNC2I1

601

Q8WVS4
SLDESGVLNVWVVVE

DYNC2I1

801

Q8WVS4
DFIPDTWQRELLDVV

DDX60

761

Q8IY21
TVSQEAEWDQIEPLL

EXD2

81

Q9NVH0
ENVLALKSVEFTWPE

HMGXB3

901

Q12766
WELLTAPLEQVADDS

MFSD6L

256

Q8IWD5
DVVQRPLLSVWLEAD

PLXNB3

1041

Q9ULL4
PLLSVWLEADAEVQA

PLXNB3

1046

Q9ULL4
IVWILVQVCEDPETS

NEK10

311

Q6ZWH5
EDLVFVLAASNLPWE

KATNAL2

391

Q8IYT4
LDSPRVTVAQLDWDV

EEF2KMT

216

Q96G04
PVDAIWIENLNSVLD

DNAH8

2206

Q96JB1
VKDLEDAAPVTTWLN

NRDE2

256

Q9H7Z3
ELPQSADVQRWEDTV

NES

941

P48681
IVNPEWAVAIAISLA

KNTC1

1681

P50748
WAVAIAISLAQDIPE

KNTC1

1686

P50748
PWIARTLDNLADELT

GBP6

591

Q6ZN66
SPQEWEALQALTVLE

GGA3

56

Q9NZ52
TLDNRVADQLWVPDT

GABRB2

106

P47870
ITIPDLTDVNAIDRW

GABRB2

476

P47870
PQSQEVDWEVELAVV

FAHD2A

151

Q96GK7
PVVLEESWDALNAIT

GCN1

2206

Q92616
PSLEETWQQTCLELE

KLF7

26

O75840
QASSPDEVALVQWTE

ATP9A

496

O75110
ESQDLTPTVPWQEIL

POLE

1241

Q07864
EFENSDVRWVITVPA

HSPA12A

191

O43301
IVWQEDPRLQDSSSE

NOL8

1071

Q76FK4
AAEIWIASLSSQPID

PACS2

166

Q86VP3
LFALIQWLAVPDEEE

MFSD6

616

Q6ZSS7
WSIIENLAIFPDTVT

EPHA7

206

Q15375
AESVTVWIDPLDATQ

BPNT2

166

Q9NX62
ELSPWIEETRALIAQ

MACF1

5791

Q9UPN3
PVWITDKELENVASF

MTMR4

196

Q9NYA4
NPELSVIVDSQEWRD

NPHP4

1011

O75161
VWSQPSDVLELLVTE

OSCAR

111

Q8IYS5
VSATIPNAEDIAEWL

HFM1

456

A2PYH4
AEWVATPELTVADVA

OBSCN

566

Q5VST9
DTEDVPWITLNSSIQ

BRCA1

366

P38398
RPILSDEDFDWTAVL

CPT1C

191

Q8TCG5
TDPREIFEVLSWLES

CNPPD1

176

Q9BV87
LSDSWQPRSLDIEVA

CD109

1131

Q6YHK3
LVSETLAWEILPQAT

FCAMR

336

Q8WWV6
TEVSSEVLTEWDPLQ

IFT43

181

Q96FT9
AAEWSLEVERVLPQL

IFT57

236

Q9NWB7
IAADIPEVVVSLAWD

DEFA1

36

P59665
IAADIPEVVVSLAWD

DEFA3

36

P59666
PLSLLTDDADVATWN

DNAH17

3401

Q9UFH2
PQSQEVDWEVELAVV

FAHD2B

151

Q6P2I3
EVVAATPTSLLISWD

FN1

1546

P02751
AAPEAWLEDERSVLQ

C1orf226

96

A1L170
ETIAVDEWIVFQSPA

DHX36

926

Q9H2U1
PTDDITLIIAVDWFL

SLC1A3

461

P43003
PWNEIETEAILSIDD

EXTL3

731

O43909
PAQENLWLDSVSLII

CACNA1I

1796

Q9P0X4
ETEINIVSWNALILP

CDON

1241

Q4KMG0
VEVLPQARASWESLD

CDC42EP1

341

Q00587
AIENEWKPADIFSTL

CCDC66

236

A2RUB6
AAVDVRTWPLILDTD

DIP2C

1101

Q9Y2E4
PDALDDSLTSLQWLQ

FOXJ1

26

Q92949
ELVITWESIPEELQN

CNTN6

716

Q9UQ52
PTEDITLIIAVDWFL

SLC1A6

486

P48664
PLNISVDTEIENVIW

LY9

66

Q9HBG7
QTLDDEWDTLPTAEV

ERP27

226

Q96DN0
DVDPEWVENLNSVLD

DYNC1H1

2306

Q14204
PETVEADAWVTEALL

KANK3

331

Q6NY19
EVSEAVLALWLPTDS

LAMB3

911

Q13751
EQLLTSDWAVHIPEE

CXorf38

206

Q8TB03
EVAVSWPEVEEALVL

EME2

211

A4GXA9
PTWVDDTRIDADAIV

FAM102A

316

Q5T9C2
VWTDLNPKAVTNDEL

DNAH9

2176

Q9NYC9
AVALAWSPQEEDRII

CST2

16

P09228
DEVPEVRQLAASLWE

DNAAF5

296

Q86Y56
AAVDIRTWPTILDTD

DIP2A

1116

Q14689
LEPFWEVLVRSTETV

HDAC6

431

Q9UBN7
SAWLVVLPAEEELVE

FGFR3

351

P22607
SWEDAALLTEANLPA

BSCL2

351

Q96G97
VDLQEELPSLWNSRV

BIN1

221

O00499
NWEVVAAVAAVPTAL

C4orf54

86

D6RIA3
PTFDIVVDTLKDWAL

SACS

3266

Q9NZJ4
WDEPAIKATFDISLV

NPEPPS

191

P55786
LDIDPETITWQRVLD

MTHFD1

521

P11586
IEPLLQDSSIWELSS

MFSD14B

481

Q5SR56
TLELIESDPVAWSDV

MYBL1

361

P10243
PVIEASQFLEWVNLE

DRP2

571

Q13474
AQWAIPVDANTLLAV

NR2E1

231

Q9Y466
ALNPVEVALVTWQSV

NUP210L

656

Q5VU65
EVESDTRIQLSWLLP

PTPRF

521

P10586
CQLIQLVWEDTSPLE

PAOX

336

Q6QHF9
EILPFTSENWDSLLL

PHF1

276

O43189
AATTLDEPIWRTELA

SYNPO2L

911

Q9H987
EATLPSPAVVAQELW

UBOX5

146

O94941
PIDKWAIADAQSAIE

SOS2

81

Q07890
NILSPSNVDWEVETD

PRUNE2

2476

Q8WUY3
WTELLDPTNVFISVE

SFXN4

46

Q6P4A7
KEALVNWDPVDQTVL

LARS2

201

Q15031
DWDIAVASLLQVTPL

NPHP3

276

Q7Z494
EVNLPILTWEECVAA

OVCH2

196

Q7RTZ1
TWAVVLELTTFNPDI

PKDREJ

1911

Q9NTG1
VEWLRDPSQELEFIA

FNTA

176

P49354
LEDLVAVDLQWSKPT

SIAE

166

Q9HAT2
TWPSQCLEELVQELA

SHROOM1

536

Q2M3G4
LLQDPSTATREEIDW

STX6

31

O43752
FWLLLPSEEEETAIQ

SH3TC1

176

Q8TE82
PLEEDETVSLVAWTT

IARS1

211

P41252
VWEEVSNSLLFVDIP

RGN

21

Q15493
PIDKWAIADAQSAIE

SOS1

81

Q07889
IPATLLEETEVWAQE

NPAP1

141

Q9NZP6
IFLAVSPEEKESWIN

PLEKHO1

111

Q53GL0
EVPIIAIDWVQIDAN

POLR2C

41

P19387
EIIIPFAISQVSESW

SLC36A3

351

Q495N2
LPTLVSTIQQDADWD

SOX6

56

P35712
VLLESPVDGWQVVEA

NCAPG2

61

Q86XI2
PNLLTLDEADATWTL

C11orf42

6

Q8N5U0
LWLSFAPVADVIAED

SLC49A3

46

Q6UXD7
VAVDFTPEEWALLDT

ZNF561

46

Q8N587
QVWRIENLELVPVDS

VIL1

401

P09327
VAVEFTPEEWALLDT

ZNF562

46

Q6V9R5
PSDQAIIEENLVLWL

TXNDC16

706

Q9P2K2
RPWNEVEDSLQAIVA

TEX13D

41

A0A0J9YY54
AEIFVESELPLSWAD

TAS1R3

656

Q7RTX0
DAVFLWDVLAPTESD

WDR90

991

Q96KV7
ALDISWSPVDEILQI

ZWILCH

226

Q9H900
VVFTDEEWSRLVPIQ

ZNF2

21

Q9BSG1
QEALEWLIRETQPIS

XPNPEP1

606

Q9NQW7
LEQEAELWAVESRLP

ZNF135

66

P52742
EDISEDPSWARVVNL

SLC5A2

641

P31639
EDTATVSWDPVQAVI

TNN

456

Q9UQP3
DIDSPQNLVTDWVTE

TNN

796

Q9UQP3
SSQEEISIWDIRILP

TRAPPC14

246

Q8WVR3
WLPEEFLERISQLDT

PYROXD2

356

Q8N2H3
WNLIPSVAVDAIAIS

SLC26A2

376

P50443
DWEEEQVSSPNILRL

UBL3

46

O95164
LWQLPTERVEEAIVA

RRS1

76

Q15050
VDQELANIDPTWIES

SRPK2

366

P78362
VLESNPLEWTVTDVV

SFMBT2

816

Q5VUG0
PEAQSEETARTLWAL

WWOX

386

Q9NZC7
SDLWVRLEESDIVPQ

TRABD2A

436

Q86V40
SQWEVSQVPLDLCEV

SEMA7A

481

O75326
EAVVADAWLTAQEPL

SPTBN4

2056

Q9H254
LPQAVFVALSDDTAW

TECPR2

891

O15040
AEQQVPLVLWSSDRD

ATP6AP1

41

Q15904
TLWVEERLPLAQSAD

SPTB

1491

P11277
RDASVAEAWLIAQEP

SPTB

2016

P11277
LLWNLAQSDDVPVDI

USP9Y

511

O00507
VVLQWLDEELPDLSV

MARS2

241

Q96GW9
WEEVVTLDEETLNTP

UNC5B

646

Q8IZJ1
QANLWLVEAEISPEL

SMO

651

Q99835
DPAVTEWVLAELVAK

TLR7

901

Q9NYK1
WDDETTVASPVILRV

PLCB2

26

Q00722
TIVTLNPPENIWTEE

TPH2

131

Q8IWU9
LDLITSNPEEARTWI

PLCH1

106

Q4KWH8
ANLINLTDEDWPVLS

SEC16B

406

Q96JE7
DISVDWFVPDTVEAL

VWA5B2

526

Q8N398
STLVLSWDPEQNEVV

ZBED6

956

P86452
PEVISQLEQGTELWV

ZNF8

71

P17098
LPQLRWEEADAVIVS

TLCD3B

26

Q71RH2
VEDVALTLTPEWTQQ

ZKSCAN3

216

Q9BRR0
WAESPAALTEVTVAD

PIEZO1

541

Q92508
ADITWSLADPAEAAV

VSIG10L

436

Q86VR7
DTTVIIWQVDPDTHL

WDR26

376

Q9H7D7
VEEILPSLSENISVW

SLC27A6

166

Q9Y2P4
TWPEDDIFRQAISLL

SC5D

21

O75845
LIDAETTAAAWPNVA

TKFC

326

Q3LXA3
VDPLEAIQWEAEAVS

TSPY26P

146

Q9H489
VAVEFTQEEWALLDP

ZNF557

41

Q8N988
QVWDSEETIFLPLLT

RIPOR1

251

Q6ZS17
DVISQTIPNPDLDWV

SETBP1

341

Q9Y6X0
WALILNISSQPEDVL

TBC1D19

261

Q8N5T2
LDEEVLQNVLELPTW

UHRF1BP1

41

Q6BDS2
VEQWALPSDTSVVLL

ZP3

376

P21754
EWEATELQPALSAAL

MARS1

86

P56192
DVRANVPEELSVWID

TOB2

81

Q14106
PEEDAFWALVQLLAS

USP6

201

P35125
LEEESPIINWSLELA

ZRANB1

411

Q9UGI0
LSAWSQVPVNLEDVA

ZNF500

216

O60304
AVSLIREEWLLDPSQ

ZKSCAN8

226

Q15776
AVEFTQEEWTLLDPA

ZNF560

116

Q96MR9
WASEPSDQLEILVTV

TARM1

206

B6A8C7
VAVNFTKEEWTLLDP

ZNF114

11

Q8NC26
DTEADVSIIALNQWP

HERV-K104

26

P63124
VPQAVLDLLTWQELE

HECTD3

726

Q5T447
AWPTLELTDQIFTLA

MYO7B

1686

Q6PIF6
WIVDPERSLLTEADA

MYOF

911

Q9NZM1