Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	acetylcholine receptor regulator activity	SPDYE1 SPDYE11 SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16	5.17e-13	27	98	8	GO:0030548
GeneOntologyMolecularFunction	neurotransmitter receptor regulator activity	SPDYE1 SPDYE11 SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16	7.21e-13	28	98	8	GO:0099602
GeneOntologyMolecularFunction	Delta4-3-oxosteroid 5beta-reductase activity	AKR1D1 AKR1C4 AKR1C2 AKR1C3	2.72e-09	5	98	4	GO:0047787
GeneOntologyMolecularFunction	ketosteroid monooxygenase activity	AKR1D1 AKR1C4 AKR1C2 AKR1C3	2.72e-09	5	98	4	GO:0047086
GeneOntologyMolecularFunction	protein kinase binding	SPDYE1 SPDYE17 SPDYE10 NBEAL1 ATG13 PFKFB2 SPDYE18 SPDYE12 SPDYE11 SPDYE15 SPDYE3 SPDYE2 SPDYE8 SPDYE21 SPDYE5 SPDYE2B MUSK SPDYE6 SPDYE14 SPDYE16	7.10e-09	873	98	20	GO:0019901
GeneOntologyMolecularFunction	kinase binding	SPDYE1 SPDYE17 SPDYE10 NBEAL1 ATG13 PFKFB2 SPDYE18 SPDYE12 SPDYE11 SPDYE15 SPDYE3 SPDYE2 SPDYE8 SPDYE21 SPDYE5 PLG SPDYE2B MUSK SPDYE6 SPDYE14 SPDYE16	7.43e-09	969	98	21	GO:0019900
GeneOntologyMolecularFunction	enone reductase activity	AKR1D1 AKR1C4 AKR1C2 AKR1C3	3.76e-08	8	98	4	GO:0035671
GeneOntologyMolecularFunction	androsterone dehydrogenase (B-specific) activity	AKR1C4 AKR1C2 AKR1C3	4.57e-07	4	98	3	GO:0047042
GeneOntologyMolecularFunction	ketoreductase activity	AKR1C4 AKR1C2 AKR1C3	4.57e-07	4	98	3	GO:0045703
GeneOntologyMolecularFunction	chlordecone reductase activity	AKR1C4 AKR1C2 AKR1C3	4.57e-07	4	98	3	GO:0047743
GeneOntologyMolecularFunction	aldose reductase (NADPH) activity	AKR1D1 AKR1C4 AKR1C2 AKR1C3	5.26e-07	14	98	4	GO:0004032
GeneOntologyMolecularFunction	trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity	AKR1C4 AKR1C2 AKR1C3	1.14e-06	5	98	3	GO:0047115
GeneOntologyMolecularFunction	15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity	AKR1C4 AKR1C2 AKR1C3	1.14e-06	5	98	3	GO:0047020
GeneOntologyMolecularFunction	17-beta-ketosteroid reductase (NADPH) activity	AKR1C4 AKR1C2 AKR1C3	1.14e-06	5	98	3	GO:0072555
GeneOntologyMolecularFunction	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity	AKR1C4 AKR1C2 AKR1C3	1.14e-06	5	98	3	GO:0047006
GeneOntologyMolecularFunction	lithocholic acid binding	AKR1C4 AKR1C2 AKR1C3	1.14e-06	5	98	3	GO:1902121
GeneOntologyMolecularFunction	geranylgeranyl reductase activity	AKR1C4 AKR1C2 AKR1C3	2.27e-06	6	98	3	GO:0045550
GeneOntologyMolecularFunction	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	AKR1C4 AKR1C2 AKR1C3	3.96e-06	7	98	3	GO:0072582
GeneOntologyMolecularFunction	5alpha-androstane-3beta,17beta-diol dehydrogenase activity	AKR1C4 AKR1C2 AKR1C3	6.31e-06	8	98	3	GO:0047024
GeneOntologyMolecularFunction	androsterone dehydrogenase activity	AKR1C4 AKR1C2 AKR1C3	6.31e-06	8	98	3	GO:0047023
GeneOntologyMolecularFunction	alcohol dehydrogenase (NADP+) activity	AKR1D1 AKR1C4 AKR1C2 AKR1C3	8.78e-06	27	98	4	GO:0008106
GeneOntologyMolecularFunction	androstan-3-alpha,17-beta-diol dehydrogenase activity	AKR1C4 AKR1C2 AKR1C3	9.43e-06	9	98	3	GO:0047044
GeneOntologyMolecularFunction	NADP+ binding	AKR1C4 AKR1C2 AKR1C3	9.43e-06	9	98	3	GO:0070401
GeneOntologyMolecularFunction	testosterone 17-beta-dehydrogenase (NADP+) activity	AKR1C4 AKR1C2 AKR1C3	1.34e-05	10	98	3	GO:0047045
GeneOntologyMolecularFunction	bile acid binding	AKR1C4 AKR1C2 AKR1C3	1.34e-05	10	98	3	GO:0032052
GeneOntologyMolecularFunction	aldo-keto reductase (NADPH) activity	AKR1D1 AKR1C4 AKR1C2 AKR1C3	1.77e-05	32	98	4	GO:0004033
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	AKR1D1 AKR1C4 AKR1C2 AKR1C3	2.26e-05	34	98	4	GO:0016628
GeneOntologyMolecularFunction	steroid dehydrogenase activity	AKR1D1 AKR1C4 AKR1C2 AKR1C3	3.93e-05	39	98	4	GO:0016229
GeneOntologyMolecularFunction	retinal dehydrogenase activity	AKR1C4 AKR1C2 AKR1C3	4.01e-05	14	98	3	GO:0001758
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	AKR1D1 AKR1C4 AKR1C2 AKR1C3	4.35e-05	40	98	4	GO:0016709
GeneOntologyMolecularFunction	Pyrin domain binding	NLRP7 NLRP2	7.13e-05	3	98	2	GO:0032090
GeneOntologyMolecularFunction	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	AKR1C4 AKR1C2 AKR1C3	1.23e-04	20	98	3	GO:0004303
GeneOntologyMolecularFunction	all-trans-retinol dehydrogenase (NAD+) activity	AKR1C4 AKR1C2 AKR1C3	2.15e-04	24	98	3	GO:0004745
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the CH-CH group of donors	AKR1D1 AKR1C4 AKR1C2 AKR1C3	2.45e-04	62	98	4	GO:0016627
GeneOntologyMolecularFunction	alcohol dehydrogenase (NAD+) activity	AKR1C4 AKR1C2 AKR1C3	2.75e-04	26	98	3	GO:0004022
GeneOntologyMolecularFunction	NADPH binding	AKR1C4 AKR1C2 AKR1C3	2.75e-04	26	98	3	GO:0070402
GeneOntologyMolecularFunction	alcohol dehydrogenase [NAD(P)+] activity	AKR1C4 AKR1C2 AKR1C3	4.23e-04	30	98	3	GO:0018455
GeneOntologyMolecularFunction	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	AKR1C4 AKR1C2 AKR1C3	5.62e-04	33	98	3	GO:0033764
GeneOntologyMolecularFunction	testosterone dehydrogenase (NAD+) activity	AKR1C4 AKR1C3	8.39e-04	9	98	2	GO:0047035
GeneOntologyMolecularFunction	aspartic-type endopeptidase inhibitor activity	NLRP7 NLRP2	8.39e-04	9	98	2	GO:0019828
GeneOntologyMolecularFunction	testosterone dehydrogenase [NAD(P)+] activity	AKR1C4 AKR1C3	1.27e-03	11	98	2	GO:0030283
GeneOntologyMolecularFunction	voltage-gated chloride channel activity	CLCN3 CLCN4	1.27e-03	11	98	2	GO:0005247
GeneOntologyMolecularFunction	interleukin-1 binding	NLRP7 NLRP2	1.52e-03	12	98	2	GO:0019966
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	AKR1C4 AKR1C2 AKR1C3	1.69e-03	48	98	3	GO:0016620
GeneOntologyMolecularFunction	monocarboxylic acid binding	AKR1C4 AKR1C2 SH3GLB1 AKR1C3	1.91e-03	107	98	4	GO:0033293
GeneOntologyMolecularFunction	monooxygenase activity	AKR1D1 AKR1C4 AKR1C2 AKR1C3	2.49e-03	115	98	4	GO:0004497
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the aldehyde or oxo group of donors	AKR1C4 AKR1C2 AKR1C3	2.63e-03	56	98	3	GO:0016903
GeneOntologyMolecularFunction	caspase binding	NLRP7 NLRP2	2.74e-03	16	98	2	GO:0089720
GeneOntologyMolecularFunction	voltage-gated monoatomic anion channel activity	CLCN3 CLCN4	3.09e-03	17	98	2	GO:0008308
GeneOntologyMolecularFunction	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	AKR1C4 AKR1C2 AKR1C3	3.20e-03	60	98	3	GO:0016655
GeneOntologyMolecularFunction	signaling receptor regulator activity	SPDYE1 SEMA5A SPDYE11 SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16	3.28e-03	616	98	9	GO:0030545
GeneOntologyMolecularFunction	NADP binding	AKR1C4 AKR1C2 AKR1C3	3.52e-03	62	98	3	GO:0050661
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	AKR1D1 AKR1C4 AKR1C2 AKR1C3	3.56e-03	127	98	4	GO:0016616
GeneOntologyMolecularFunction	steroid binding	AKR1D1 AKR1C4 AKR1C2 AKR1C3	4.19e-03	133	98	4	GO:0005496
GeneOntologyMolecularFunction	oxidoreductase activity, acting on CH-OH group of donors	AKR1D1 AKR1C4 AKR1C2 AKR1C3	4.78e-03	138	98	4	GO:0016614
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	DOCK2 ARFGEF2 ARFGEF1 HERC1 PREX1	5.64e-03	231	98	5	GO:0005085
GeneOntologyMolecularFunction	protein kinase A regulatory subunit binding	ARFGEF2 ARFGEF1	6.65e-03	25	98	2	GO:0034237
GeneOntologyMolecularFunction	cullin family protein binding	DCUN1D5 DCUN1D4	7.18e-03	26	98	2	GO:0097602
GeneOntologyMolecularFunction	myosin binding	ARFGEF2 ARFGEF1 SPTBN5	8.47e-03	85	98	3	GO:0017022
GeneOntologyBiologicalProcess	positive regulation of cyclin-dependent protein serine/threonine kinase activity	SPDYE1 SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16	1.07e-11	25	90	7	GO:0045737
GeneOntologyBiologicalProcess	positive regulation of cyclin-dependent protein kinase activity	SPDYE1 SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16	2.61e-11	28	90	7	GO:1904031
GeneOntologyBiologicalProcess	regulation of cyclin-dependent protein serine/threonine kinase activity	SPDYE1 SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16	2.07e-07	96	90	7	GO:0000079
GeneOntologyBiologicalProcess	regulation of cyclin-dependent protein kinase activity	SPDYE1 SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16	2.74e-07	100	90	7	GO:1904029
GeneOntologyBiologicalProcess	response to jasmonic acid	AKR1C4 AKR1C2 AKR1C3	3.20e-07	4	90	3	GO:0009753
GeneOntologyBiologicalProcess	progesterone catabolic process	AKR1C4 AKR1C2 AKR1C3	3.20e-07	4	90	3	GO:0006709
GeneOntologyBiologicalProcess	cellular response to jasmonic acid stimulus	AKR1C4 AKR1C2 AKR1C3	3.20e-07	4	90	3	GO:0071395
GeneOntologyBiologicalProcess	C21-steroid hormone catabolic process	AKR1C4 AKR1C2 AKR1C3	3.20e-07	4	90	3	GO:0008208
GeneOntologyBiologicalProcess	farnesol metabolic process	AKR1C4 AKR1C2 AKR1C3	7.98e-07	5	90	3	GO:0016487
GeneOntologyBiologicalProcess	farnesol catabolic process	AKR1C4 AKR1C2 AKR1C3	7.98e-07	5	90	3	GO:0016488
GeneOntologyBiologicalProcess	negative regulation of isoprenoid metabolic process	AKR1C4 AKR1C2 AKR1C3	7.98e-07	5	90	3	GO:0045827
GeneOntologyBiologicalProcess	sesquiterpenoid catabolic process	AKR1C4 AKR1C2 AKR1C3	7.98e-07	5	90	3	GO:0016107
GeneOntologyBiologicalProcess	olefinic compound catabolic process	AKR1C4 AKR1C2 AKR1C3	7.98e-07	5	90	3	GO:0120256
GeneOntologyBiologicalProcess	negative regulation of retinoic acid biosynthetic process	AKR1C4 AKR1C2 AKR1C3	7.98e-07	5	90	3	GO:1900053
GeneOntologyBiologicalProcess	sesquiterpenoid metabolic process	AKR1C4 AKR1C2 AKR1C3	1.59e-06	6	90	3	GO:0006714
GeneOntologyBiologicalProcess	polyprenol catabolic process	AKR1C4 AKR1C2 AKR1C3	1.59e-06	6	90	3	GO:0016095
GeneOntologyBiologicalProcess	response to prostaglandin D	AKR1C4 AKR1C2 AKR1C3	2.78e-06	7	90	3	GO:0071798
GeneOntologyBiologicalProcess	cellular response to prostaglandin D stimulus	AKR1C4 AKR1C2 AKR1C3	2.78e-06	7	90	3	GO:0071799
GeneOntologyBiologicalProcess	regulation of retinoic acid biosynthetic process	AKR1C4 AKR1C2 AKR1C3	2.78e-06	7	90	3	GO:1900052
GeneOntologyBiologicalProcess	daunorubicin metabolic process	AKR1C4 AKR1C2 AKR1C3	6.62e-06	9	90	3	GO:0044597
GeneOntologyBiologicalProcess	doxorubicin metabolic process	AKR1C4 AKR1C2 AKR1C3	9.43e-06	10	90	3	GO:0044598
GeneOntologyBiologicalProcess	regulation of isoprenoid metabolic process	AKR1C4 AKR1C2 AKR1C3	9.43e-06	10	90	3	GO:0019747
GeneOntologyBiologicalProcess	negative regulation of vitamin metabolic process	AKR1C4 AKR1C2 AKR1C3	9.43e-06	10	90	3	GO:0046137
GeneOntologyBiologicalProcess	polyketide metabolic process	AKR1C4 AKR1C2 AKR1C3	9.43e-06	10	90	3	GO:0030638
GeneOntologyBiologicalProcess	aminoglycoside antibiotic metabolic process	AKR1C4 AKR1C2 AKR1C3	9.43e-06	10	90	3	GO:0030647
GeneOntologyBiologicalProcess	regulation of testosterone biosynthetic process	AKR1C4 AKR1C2 AKR1C3	1.29e-05	11	90	3	GO:2000224
GeneOntologyBiologicalProcess	terpenoid catabolic process	AKR1C4 AKR1C2 AKR1C3	1.29e-05	11	90	3	GO:0016115
GeneOntologyBiologicalProcess	steroid catabolic process	AKR1D1 AKR1C4 AKR1C2 AKR1C3	1.42e-05	34	90	4	GO:0006706
GeneOntologyBiologicalProcess	organic hydroxy compound catabolic process	MAOA AKR1D1 AKR1C4 AKR1C2 AKR1C3	1.68e-05	73	90	5	GO:1901616
GeneOntologyBiologicalProcess	positive regulation of protein serine/threonine kinase activity	SPDYE1 SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16	2.18e-05	193	90	7	GO:0071902
GeneOntologyBiologicalProcess	retinoic acid biosynthetic process	AKR1C4 AKR1C2 AKR1C3	2.82e-05	14	90	3	GO:0002138
GeneOntologyBiologicalProcess	isoprenoid catabolic process	AKR1C4 AKR1C2 AKR1C3	2.82e-05	14	90	3	GO:0008300
GeneOntologyBiologicalProcess	diterpenoid biosynthetic process	AKR1C4 AKR1C2 AKR1C3	3.52e-05	15	90	3	GO:0016102
GeneOntologyBiologicalProcess	testosterone biosynthetic process	AKR1C4 AKR1C2 AKR1C3	4.32e-05	16	90	3	GO:0061370
GeneOntologyBiologicalProcess	negative regulation of hormone metabolic process	AKR1C4 AKR1C2 AKR1C3	4.32e-05	16	90	3	GO:0032351
GeneOntologyBiologicalProcess	C21-steroid hormone metabolic process	AKR1D1 AKR1C4 AKR1C2 AKR1C3	4.40e-05	45	90	4	GO:0008207
GeneOntologyBiologicalProcess	alcohol catabolic process	AKR1D1 AKR1C4 AKR1C2 AKR1C3	5.24e-05	47	90	4	GO:0046164
GeneOntologyBiologicalProcess	positive regulation of Rac protein signal transduction	DOCK2 MUSK TNS3	6.25e-05	18	90	3	GO:0035022
GeneOntologyBiologicalProcess	regulation of vitamin metabolic process	AKR1C4 AKR1C2 AKR1C3	6.25e-05	18	90	3	GO:0030656
GeneOntologyBiologicalProcess	hormone catabolic process	AKR1C4 AKR1C2 AKR1C3	1.01e-04	21	90	3	GO:0042447
GeneOntologyBiologicalProcess	terpenoid biosynthetic process	AKR1C4 AKR1C2 AKR1C3	1.01e-04	21	90	3	GO:0016114
GeneOntologyBiologicalProcess	regulation of retinoic acid receptor signaling pathway	AKR1C4 AKR1C2 AKR1C3	1.01e-04	21	90	3	GO:0048385
GeneOntologyBiologicalProcess	retinal metabolic process	AKR1C4 AKR1C2 AKR1C3	1.01e-04	21	90	3	GO:0042574
GeneOntologyBiologicalProcess	ketone catabolic process	AKR1C4 AKR1C2 AKR1C3	1.01e-04	21	90	3	GO:0042182
GeneOntologyBiologicalProcess	parturition	AKR1C4 AKR1C2 AKR1C3	1.17e-04	22	90	3	GO:0007567
GeneOntologyBiologicalProcess	glycoside metabolic process	AKR1C4 AKR1C2 AKR1C3	1.17e-04	22	90	3	GO:0016137
GeneOntologyBiologicalProcess	progesterone metabolic process	AKR1C4 AKR1C2 AKR1C3	1.17e-04	22	90	3	GO:0042448
GeneOntologyBiologicalProcess	tertiary alcohol metabolic process	AKR1C4 AKR1C2 AKR1C3	1.17e-04	22	90	3	GO:1902644
GeneOntologyBiologicalProcess	cellular response to prostaglandin stimulus	AKR1C4 AKR1C2 AKR1C3	1.34e-04	23	90	3	GO:0071379
GeneOntologyBiologicalProcess	primary alcohol catabolic process	AKR1C4 AKR1C2 AKR1C3	1.34e-04	23	90	3	GO:0034310
GeneOntologyBiologicalProcess	positive regulation of protein neddylation	DCUN1D5 DCUN1D4	1.87e-04	5	90	2	GO:2000436
GeneOntologyBiologicalProcess	regulation of ketone biosynthetic process	AKR1C4 AKR1C2 AKR1C3	1.94e-04	26	90	3	GO:0010566
GeneOntologyBiologicalProcess	response to fatty acid	AKR1C4 AKR1C2 AACS AKR1C3	2.36e-04	69	90	4	GO:0070542
GeneOntologyBiologicalProcess	negative regulation of mRNA splicing, via spliceosome	AKR1C4 AKR1C2 AKR1C3	2.43e-04	28	90	3	GO:0048025
GeneOntologyBiologicalProcess	polyprenol metabolic process	AKR1C4 AKR1C2 AKR1C3	2.70e-04	29	90	3	GO:0016093
GeneOntologyBiologicalProcess	negative regulation of mRNA processing	AKR1C4 AKR1C2 AKR1C3	2.70e-04	29	90	3	GO:0050686
GeneOntologyBiologicalProcess	regulation of endothelial cell apoptotic process	SEMA5A AKR1C4 AKR1C2 AKR1C3	3.09e-04	74	90	4	GO:2000351
GeneOntologyBiologicalProcess	positive regulation of endothelial cell apoptotic process	AKR1C4 AKR1C2 AKR1C3	3.64e-04	32	90	3	GO:2000353
GeneOntologyBiologicalProcess	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	ARFGEF1 SEMA5A AKR1C4 AKR1C2 AKR1C3 MUSK	3.78e-04	217	90	6	GO:0051897
GeneOntologyBiologicalProcess	positive regulation of kinase activity	SPDYE1 SPDYE3 SPDYE2 SPDYE5 SPDYE2B MUSK SPDYE6 SPDYE16	3.93e-04	405	90	8	GO:0033674
GeneOntologyBiologicalProcess	endothelial cell apoptotic process	SEMA5A AKR1C4 AKR1C2 AKR1C3	3.97e-04	79	90	4	GO:0072577
GeneOntologyBiologicalProcess	negative regulation of RNA splicing	AKR1C4 AKR1C2 AKR1C3	3.99e-04	33	90	3	GO:0033119
GeneOntologyBiologicalProcess	positive regulation of cell cycle	SPDYE1 SPDYE3 SPDYE2 SPDYE5 TBX20 SPDYE2B SPDYE6 SPDYE16	4.06e-04	407	90	8	GO:0045787
GeneOntologyBiologicalProcess	olefinic compound biosynthetic process	AKR1C4 AKR1C2 AKR1C3	4.75e-04	35	90	3	GO:0120255
GeneOntologyBiologicalProcess	regulation of Rac protein signal transduction	DOCK2 MUSK TNS3	4.75e-04	35	90	3	GO:0035020
GeneOntologyBiologicalProcess	small molecule catabolic process	AMT UPB1 AKR1D1 AKR1C4 PFKFB2 AKR1C2 AKR1C3 ABCD1	5.07e-04	421	90	8	GO:0044282
GeneOntologyBiologicalProcess	response to prostaglandin	AKR1C4 AKR1C2 AKR1C3	5.17e-04	36	90	3	GO:0034694
GeneOntologyBiologicalProcess	isoprenoid biosynthetic process	AKR1C4 AKR1C2 AKR1C3	5.17e-04	36	90	3	GO:0008299
GeneOntologyBiologicalProcess	retinoic acid receptor signaling pathway	AKR1C4 AKR1C2 AKR1C3	6.07e-04	38	90	3	GO:0048384
GeneOntologyBiologicalProcess	positive regulation of reactive oxygen species metabolic process	AKR1C4 AKR1C2 CLCN3 AKR1C3	6.24e-04	89	90	4	GO:2000379
GeneOntologyBiologicalProcess	endomembrane system organization	STAM2 ARFGEF2 ARFGEF1 SEC31A TRIP11 SPTBN5 SH3GLB1 CLCN3 ABCD1 ZW10	6.91e-04	672	90	10	GO:0010256
GeneOntologyBiologicalProcess	retinoic acid metabolic process	AKR1C4 AKR1C2 AKR1C3	7.06e-04	40	90	3	GO:0042573
GeneOntologyBiologicalProcess	cellular response to fatty acid	AKR1C4 AKR1C2 AKR1C3	8.15e-04	42	90	3	GO:0071398
GeneOntologyBiologicalProcess	glycosyl compound metabolic process	UPB1 AKR1C4 AKR1C2 AKR1C3	8.29e-04	96	90	4	GO:1901657
GeneOntologyBiologicalProcess	positive regulation of protein kinase activity	SPDYE1 SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16	8.54e-04	350	90	7	GO:0045860
GeneOntologyBiologicalProcess	regulation of protein serine/threonine kinase activity	SPDYE1 SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16	9.74e-04	358	90	7	GO:0071900
GeneOntologyBiologicalProcess	regulation of actin polymerization or depolymerization	SPTBN2 ARFGEF1 SEMA5A SPTBN5 PREX1	1.07e-03	177	90	5	GO:0008064
GeneOntologyBiologicalProcess	regulation of actin filament length	SPTBN2 ARFGEF1 SEMA5A SPTBN5 PREX1	1.16e-03	180	90	5	GO:0030832
GeneOntologyBiologicalProcess	positive regulation of transferase activity	SPDYE1 SPDYE3 SPDYE2 SPDYE5 SPDYE2B MUSK SPDYE6 SPDYE16	1.35e-03	490	90	8	GO:0051347
GeneOntologyBiologicalProcess	regulation of reactive oxygen species metabolic process	AKR1C4 AKR1C2 CLCN3 AKR1C3 ABCD1	1.40e-03	188	90	5	GO:2000377
GeneOntologyBiologicalProcess	intraciliary transport	MAK CILK1 DAW1	1.61e-03	53	90	3	GO:0042073
GeneOntologyBiologicalProcess	reactive oxygen species metabolic process	AKR1C4 AKR1C2 CLCN3 AKR1C3 ABCD1 PREX1	1.73e-03	291	90	6	GO:0072593
GeneOntologyBiologicalProcess	prostaglandin metabolic process	AKR1C4 AKR1C2 AKR1C3	1.88e-03	56	90	3	GO:0006693
GeneOntologyBiologicalProcess	prostanoid metabolic process	AKR1C4 AKR1C2 AKR1C3	1.98e-03	57	90	3	GO:0006692
GeneOntologyBiologicalProcess	ketone biosynthetic process	AKR1C4 AKR1C2 AKR1C3	1.98e-03	57	90	3	GO:0042181
GeneOntologyBiologicalProcess	regulation of actin filament organization	SPTBN2 ARFGEF1 SEMA5A SPTBN5 RHPN2P1 PREX1	2.02e-03	300	90	6	GO:0110053
GeneOntologyBiologicalProcess	regulation of hormone metabolic process	AKR1C4 AKR1C2 AKR1C3	2.08e-03	58	90	3	GO:0032350
GeneOntologyBiologicalProcess	positive regulation of epithelial cell apoptotic process	AKR1C4 AKR1C2 AKR1C3	2.30e-03	60	90	3	GO:1904037
GeneOntologyBiologicalProcess	Rac protein signal transduction	DOCK2 MUSK TNS3	2.30e-03	60	90	3	GO:0016601
MousePheno	parturition failure	AKR1C4 AKR1C2 AKR1C3	1.73e-05	10	75	3	MP:0012010
MousePheno	hypermyelination	AKR1C4 AKR1C2 AKR1C3	2.37e-05	11	75	3	MP:0010050
MousePheno	increased oligodendrocyte number	AKR1C4 AKR1C2 AKR1C3	4.08e-05	13	75	3	MP:0010160
MousePheno	increased circulating progesterone level	AKR1C4 AKR1C2 AKR1C3	6.44e-05	15	75	3	MP:0005186
MousePheno	long stride length	AKR1C4 AKR1C2 AKR1C3	6.44e-05	15	75	3	MP:0010540
MousePheno	long gestation period	AKR1C4 AKR1C2 AKR1C3	6.44e-05	15	75	3	MP:0002293
MousePheno	decreased vocalization	AKR1C4 AKR1C2 AKR1C3 PREX1	1.05e-04	46	75	4	MP:0020351
MousePheno	abnormal gestational length	AKR1C4 AKR1C2 AKR1C3	1.14e-04	18	75	3	MP:0002292
MousePheno	dysmyelination	AKR1C4 AKR1C2 AKR1C3	1.58e-04	20	75	3	MP:0013438
MousePheno	decreased litter size	MAK BRIP1 NLRP7 AKR1C4 NLRP2 AKR1C2 RNF141 AKR1C3 TNS1	1.90e-04	380	75	9	MP:0001935
MousePheno	abnormal litter size	MAK BRIP1 NLRP7 AKR1C4 NLRP2 AKR1C2 RNF141 AKR1C3 TNS1	2.73e-04	399	75	9	MP:0001933
MousePheno	decreased oligodendrocyte number	AKR1C4 AKR1C2 AKR1C3	3.13e-04	25	75	3	MP:0009808
MousePheno	abnormal cerebral cortex morphology	MAOA ARFGEF2 ARFGEF1 CLCN3 STXBP3 SUZ12 WDFY3 DNAH5	3.63e-04	328	75	8	MP:0000788
Domain	Spy1	SPDYE1 SPDYE3 SPDYE2 SPDYE21 SPDYE5 SPDYE2B SPDYE6 SPDYE16	3.45e-17	11	90	8	PF11357
Domain	Speedy	SPDYE1 SPDYE3 SPDYE2 SPDYE21 SPDYE5 SPDYE2B SPDYE6 SPDYE16	3.45e-17	11	90	8	IPR020984
Domain	ALDOKETO_REDUCTASE_1	AKR1D1 AKR1C4 AKR1C2 AKR1C3	1.04e-07	10	90	4	PS00798
Domain	Aldo/ket_reductase_CS	AKR1D1 AKR1C4 AKR1C2 AKR1C3	1.04e-07	10	90	4	IPR018170
Domain	Aldo/keto_reductase	AKR1D1 AKR1C4 AKR1C2 AKR1C3	1.04e-07	10	90	4	IPR020471
Domain	ALDOKETO_REDUCTASE_2	AKR1D1 AKR1C4 AKR1C2 AKR1C3	1.04e-07	10	90	4	PS00062
Domain	ALDOKETO_REDUCTASE_3	AKR1D1 AKR1C4 AKR1C2 AKR1C3	1.04e-07	10	90	4	PS00063
Domain	-	AKR1D1 AKR1C4 AKR1C2 AKR1C3	8.78e-07	16	90	4	3.20.20.100
Domain	NADP_OxRdtase_dom	AKR1D1 AKR1C4 AKR1C2 AKR1C3	1.14e-06	17	90	4	IPR023210
Domain	Aldo_ket_red	AKR1D1 AKR1C4 AKR1C2 AKR1C3	1.14e-06	17	90	4	PF00248
Domain	Aldo/ket_red/Kv-b	AKR1D1 AKR1C4 AKR1C2 AKR1C3	1.14e-06	17	90	4	IPR001395
Domain	WD40	NBEAL1 WDR46 SEC31A WDR38 DAW1 WDFY3 PAK1IP1 HERC1 WDR17	4.38e-06	259	90	9	PF00400
Domain	-	NBEAL1 WDR46 SEMA5A SEC31A WDR38 DAW1 WDFY3 PAK1IP1 HERC1 WDR17	4.59e-06	333	90	10	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	NBEAL1 WDR46 SEMA5A SEC31A WDR38 DAW1 WDFY3 PAK1IP1 HERC1 WDR17	4.84e-06	335	90	10	IPR015943
Domain	WD40	NBEAL1 WDR46 SEC31A WDR38 DAW1 WDFY3 PAK1IP1 HERC1 WDR17	5.78e-06	268	90	9	SM00320
Domain	WD40_repeat	NBEAL1 WDR46 SEC31A WDR38 DAW1 WDFY3 PAK1IP1 HERC1 WDR17	6.51e-06	272	90	9	IPR001680
Domain	WD_REPEATS_1	NBEAL1 WDR46 SEC31A WDR38 DAW1 WDFY3 PAK1IP1 HERC1 WDR17	7.76e-06	278	90	9	PS00678
Domain	WD_REPEATS_2	NBEAL1 WDR46 SEC31A WDR38 DAW1 WDFY3 PAK1IP1 HERC1 WDR17	7.99e-06	279	90	9	PS50082
Domain	WD_REPEATS_REGION	NBEAL1 WDR46 SEC31A WDR38 DAW1 WDFY3 PAK1IP1 HERC1 WDR17	7.99e-06	279	90	9	PS50294
Domain	WD40_repeat_dom	NBEAL1 WDR46 SEC31A WDR38 DAW1 WDFY3 PAK1IP1 HERC1 WDR17	1.32e-05	297	90	9	IPR017986
Domain	TF_homeodomain_male	PHTF2 PHTF1	2.30e-05	2	90	2	IPR021980
Domain	Phtf-FEM1B_bdg	PHTF2 PHTF1	2.30e-05	2	90	2	PF12129
Domain	DUF1981	ARFGEF2 ARFGEF1	1.37e-04	4	90	2	PF09324
Domain	Sec7_N	ARFGEF2 ARFGEF1	1.37e-04	4	90	2	IPR032691
Domain	Sec7_N	ARFGEF2 ARFGEF1	1.37e-04	4	90	2	PF12783
Domain	DCB_dom	ARFGEF2 ARFGEF1	1.37e-04	4	90	2	IPR032629
Domain	Tensin_PTB	TNS1 TNS3	1.37e-04	4	90	2	IPR033929
Domain	DCB	ARFGEF2 ARFGEF1	1.37e-04	4	90	2	PF16213
Domain	Sec7_C	ARFGEF2 ARFGEF1	1.37e-04	4	90	2	IPR015403
Domain	WD40_repeat_CS	WDR38 DAW1 WDFY3 PAK1IP1 HERC1 WDR17	1.42e-04	164	90	6	IPR019775
Domain	PH_dom-like	NBEAL1 SPTBN2 PLEKHH1 SPTBN5 TBC1D1 WDFY3 TNS1 PREX1 TNS3	2.12e-04	426	90	9	IPR011993
Domain	DCN-prot	DCUN1D5 DCUN1D4	2.27e-04	5	90	2	IPR014764
Domain	PONY_dom	DCUN1D5 DCUN1D4	2.27e-04	5	90	2	IPR005176
Domain	DUF4704	NBEAL1 WDFY3	2.27e-04	5	90	2	IPR031570
Domain	DCUN1	DCUN1D5 DCUN1D4	2.27e-04	5	90	2	PS51229
Domain	DUF4704	NBEAL1 WDFY3	2.27e-04	5	90	2	PF15787
Domain	Cullin_binding	DCUN1D5 DCUN1D4	2.27e-04	5	90	2	PF03556
Domain	PH_BEACH	NBEAL1 WDFY3	3.40e-04	6	90	2	PF14844
Domain	PH-BEACH_dom	NBEAL1 WDFY3	6.31e-04	8	90	2	IPR023362
Domain	PTEN_C2	TNS1 TNS3	6.31e-04	8	90	2	SM01326
Domain	PTEN_C2	TNS1 TNS3	6.31e-04	8	90	2	PF10409
Domain	PTB	TNS1 TNS3	6.31e-04	8	90	2	PF08416
Domain	PTB	TNS1 TNS3	6.31e-04	8	90	2	IPR013625
Domain	C2_TENSIN	TNS1 TNS3	6.31e-04	8	90	2	PS51182
Domain	-	NBEAL1 WDFY3	6.31e-04	8	90	2	2.30.29.40
Domain	Tensin_lipid_phosphatase_dom	TNS1 TNS3	6.31e-04	8	90	2	IPR029023
Domain	PH_BEACH	NBEAL1 WDFY3	6.31e-04	8	90	2	PS51783
Domain	Tensin_C2-dom	TNS1 TNS3	6.31e-04	8	90	2	IPR014020
Domain	G-protein_beta_WD-40_rep	WDR38 DAW1 PAK1IP1 WDR17	7.58e-04	85	90	4	IPR020472
Domain	Cl-channel_core	CLCN3 CLCN4	8.09e-04	9	90	2	IPR014743
Domain	BEACH_dom	NBEAL1 WDFY3	8.09e-04	9	90	2	IPR000409
Domain	PPASE_TENSIN	TNS1 TNS3	8.09e-04	9	90	2	PS51181
Domain	-	CLCN3 CLCN4	8.09e-04	9	90	2	1.10.3080.10
Domain	PH_dom-spectrin-type	SPTBN2 SPTBN5	8.09e-04	9	90	2	IPR001605
Domain	Voltage_CLC	CLCN3 CLCN4	8.09e-04	9	90	2	PF00654
Domain	BEACH	NBEAL1 WDFY3	8.09e-04	9	90	2	PS50197
Domain	Cl-channel_volt-gated	CLCN3 CLCN4	8.09e-04	9	90	2	IPR001807
Domain	Beach	NBEAL1 WDFY3	8.09e-04	9	90	2	PF02138
Domain	-	NBEAL1 WDFY3	8.09e-04	9	90	2	1.10.1540.10
Domain	Beach	NBEAL1 WDFY3	8.09e-04	9	90	2	SM01026
Domain	PTB	TBC1D1 TNS1 TNS3	9.40e-04	40	90	3	SM00462
Domain	PTB/PI_dom	TBC1D1 TNS1 TNS3	1.01e-03	41	90	3	IPR006020
Domain	-	ARFGEF2 ARFGEF1	2.31e-03	15	90	2	1.10.1000.11
Domain	Sec7	ARFGEF2 ARFGEF1	2.31e-03	15	90	2	PF01369
Domain	Sec7_alpha_orthog	ARFGEF2 ARFGEF1	2.31e-03	15	90	2	IPR023394
Domain	Sec7	ARFGEF2 ARFGEF1	2.64e-03	16	90	2	SM00222
Domain	CBS	CLCN3 CLCN4	2.64e-03	16	90	2	SM00116
Domain	SEC7	ARFGEF2 ARFGEF1	2.64e-03	16	90	2	PS50190
Domain	Sec7_dom	ARFGEF2 ARFGEF1	2.64e-03	16	90	2	IPR000904
Domain	-	SPTBN2 PLEKHH1 SPTBN5 TBC1D1 TNS1 PREX1 TNS3	2.81e-03	391	90	7	2.30.29.30
Domain	CBS_dom	CLCN3 CLCN4	4.12e-03	20	90	2	IPR000644
Domain	CBS	CLCN3 CLCN4	4.12e-03	20	90	2	PF00571
Domain	CBS	CLCN3 CLCN4	4.12e-03	20	90	2	PS51371
Pathway	REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL	AKR1D1 AKR1C4 AKR1C2 AKR1C3	3.04e-07	13	66	4	M17842
Pathway	REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL	AKR1D1 AKR1C4 AKR1C2 AKR1C3	3.04e-07	13	66	4	MM14747
Pathway	WP_GLUCOCORTICOID_BIOSYNTHESIS	AKR1D1 AKR1C4 AKR1C2 AKR1C3	4.23e-07	14	66	4	M46449
Pathway	REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_27_HYDROXYCHOLESTEROL	AKR1D1 AKR1C4 AKR1C2 AKR1C3	4.23e-07	14	66	4	M27074
Pathway	WP_MINERALOCORTICOID_BIOSYNTHESIS	AKR1D1 AKR1C4 AKR1C2 AKR1C3	4.23e-07	14	66	4	M46453
Pathway	REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_27_HYDROXYCHOLESTEROL	AKR1D1 AKR1C4 AKR1C2 AKR1C3	4.23e-07	14	66	4	MM14748
Pathway	REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL	AKR1D1 AKR1C4 AKR1C2 AKR1C3	3.63e-06	23	66	4	M1926
Pathway	REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL	AKR1D1 AKR1C4 AKR1C2 AKR1C3	3.63e-06	23	66	4	MM14741
Pathway	WP_BENZOAPYRENE_METABOLISM	AKR1C4 AKR1C2 AKR1C3	8.07e-06	9	66	3	M39344
Pathway	KEGG_MEDICUS_ENV_FACTOR_METALS_TO_KEAP1_NRF2_SIGNALIG_PATHWAY	AKR1C4 AKR1C2 AKR1C3	8.07e-06	9	66	3	M47817
Pathway	KEGG_MEDICUS_ENV_FACTOR_BENZO_A_PYRENRE_TO_CYP_MEDIATED_METABOLISM	AKR1C4 AKR1C2 AKR1C3	1.57e-05	11	66	3	M47812
Pathway	REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS	AKR1D1 AKR1C4 AKR1C2 AKR1C3	1.62e-05	33	66	4	M5967
Pathway	REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS	AKR1D1 AKR1C4 AKR1C2 AKR1C3	1.62e-05	33	66	4	MM14737
Pathway	REACTOME_SYNTHESIS_OF_PROSTAGLANDINS_PG_AND_THROMBOXANES_TX	AKR1C4 AKR1C2 AKR1C3	4.28e-05	15	66	3	MM14870
Pathway	REACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM	AKR1D1 AKR1C4 AKR1C2 AKR1C3	5.17e-05	44	66	4	M499
Pathway	REACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM	AKR1D1 AKR1C4 AKR1C2 AKR1C3	5.65e-05	45	66	4	MM14751
Pathway	KEGG_STEROID_HORMONE_BIOSYNTHESIS	AKR1D1 AKR1C4 AKR1C2 AKR1C3	1.25e-04	55	66	4	M14933
Pathway	REACTOME_PREDNISONE_ADME	AKR1C4 AKR1C2 AKR1C3	1.62e-04	23	66	3	MM16639
Pathway	REACTOME_RA_BIOSYNTHESIS_PATHWAY	AKR1C4 AKR1C2 AKR1C3	2.95e-04	28	66	3	MM15188
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SPTBN2 SPTBN5	9.48e-04	10	66	2	MM15112
Pathway	WP_ALTERNATIVE_PATHWAY_OF_FETAL_ANDROGEN_SYNTHESIS	AKR1C4 AKR1C2	1.16e-03	11	66	2	M39749
Pathway	REACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS	AKR1C4 AKR1C2 AKR1C3	1.21e-03	45	66	3	MM15344
Pathway	REACTOME_SIGNALING_BY_RETINOIC_ACID	AKR1C4 AKR1C2 AKR1C3	1.55e-03	49	66	3	MM15186
Pubmed	Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins.	SPDYE1 SPDYE17 SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16	4.46e-18	13	100	8	15611625
Pubmed	Murine fertility and spermatogenesis are independent of the testis-specific Spdye4a gene.	SPDYE1 SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16	4.70e-17	9	100	7	36272447
Pubmed	Characterization of a new family of cyclin-dependent kinase activators.	SPDYE1 SPDYE17 SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16	8.35e-17	17	100	8	15574121
Pubmed	A cluster of eight hydroxysteroid dehydrogenase genes belonging to the aldo-keto reductase supergene family on mouse chromosome 13.	AKR1D1 AKR1C4 AKR1C2 AKR1C3	2.24e-09	7	100	4	12562828
Pubmed	Evolution of the Cdk-activator Speedy/RINGO in vertebrates.	SPDYE17 SPDYE2 SPDYE6	2.31e-08	3	100	3	22763696
Pubmed	Studies on a Tyr residue critical for the binding of coenzyme and substrate in mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21): structure of the Y224D mutant enzyme.	AKR1C4 AKR1C2 AKR1C3	9.21e-08	4	100	3	20124700
Pubmed	Structure and activity of the murine type 5 17beta-hydroxysteroid dehydrogenase gene(1).	AKR1C4 AKR1C2 AKR1C3	9.21e-08	4	100	3	10500239
Pubmed	Enzymatic properties of a member (AKR1C20) of the aldo-keto reductase family.	AKR1C4 AKR1C2 AKR1C3	9.21e-08	4	100	3	16508162
Pubmed	AKR1C isoforms represent a novel cellular target for jasmonates alongside their mitochondrial-mediated effects.	AKR1C4 AKR1C2 AKR1C3	9.21e-08	4	100	3	19487289
Pubmed	Cloning and chromosomal localization of mouse 20alpha-hydroxysteroid dehydrogenase gene.	AKR1C4 AKR1C2 AKR1C3	9.21e-08	4	100	3	14967952
Pubmed	Assignment of HSD17B5 encoding type 5 17 beta-hydroxysteroid dehydrogenase to human chromosome bands 10p15-->p14 and mouse chromosome 13 region A2 by in situ hybridization: identification of a new syntenic relationship.	AKR1C4 AKR1C2 AKR1C3	9.21e-08	4	100	3	10393440
Pubmed	Localization of 20alpha-hydroxysteroid dehydrogenase mRNA in mouse brain by in situ hybridization.	AKR1C4 AKR1C2 AKR1C3	9.21e-08	4	100	3	15193432
Pubmed	Mouse Akr1cl gene product is a prostaglandin D2 11-ketoreductase with strict substrate specificity.	AKR1C4 AKR1C2 AKR1C3	9.21e-08	4	100	3	31479646
Pubmed	Characterization and functional analysis of the 5'-flanking region of the mouse 20alpha-hydroxysteroid dehydrogenase gene.	AKR1C4 AKR1C2 AKR1C3	9.21e-08	4	100	3	15222881
Pubmed	Isolation and characterization of a cDNA encoding mouse 3alpha-hydroxysteroid dehydrogenase: an androgen-inactivating enzyme selectively expressed in female tissues.	AKR1C4 AKR1C2 AKR1C3	9.21e-08	4	100	3	16191478
Pubmed	Characterization of two isoforms of mouse 3(17)alpha-hydroxysteroid dehydrogenases of the aldo-keto reductase family.	AKR1C4 AKR1C2 AKR1C3	9.21e-08	4	100	3	15577209
Pubmed	Identification of an interleukin-3-regulated aldoketo reductase gene in myeloid cells which may function in autocrine regulation of myelopoiesis.	AKR1C4 AKR1C2 AKR1C3	9.21e-08	4	100	3	10702227
Pubmed	Crystal structures of mouse 17alpha-hydroxysteroid dehydrogenase (apoenzyme and enzyme-NADP(H) binary complex): identification of molecular determinants responsible for the unique 17alpha-reductive activity of this enzyme.	AKR1C4 AKR1C2 AKR1C3	9.21e-08	4	100	3	17034817
Pubmed	Several distinct enzymes catalyze 20alpha-hydroxysteroid dehydrogenase activity in mouse liver and kidney.	AKR1C4 AKR1C2 AKR1C3	9.21e-08	4	100	3	17629694
Pubmed	RECON-Dependent Inflammation in Hepatocytes Enhances Listeria monocytogenes Cell-to-Cell Spread.	AKR1C4 AKR1C2 AKR1C3	9.21e-08	4	100	3	29764944
Pubmed	Cloning and characterization of two novel aldo-keto reductases (AKR1C12 and AKR1C13) from mouse stomach.	AKR1C4 AKR1C2 AKR1C3	9.21e-08	4	100	3	10526179
Pubmed	Characterization of rat and mouse NAD+-dependent 3alpha/17beta/20alpha-hydroxysteroid dehydrogenases and identification of substrate specificity determinants by site-directed mutagenesis.	AKR1C4 AKR1C2 AKR1C3	9.21e-08	4	100	3	17888864
Pubmed	Mouse 17alpha-hydroxysteroid dehydrogenase (AKR1C21) binds steroids differently from other aldo-keto reductases: identification and characterization of amino acid residues critical for substrate binding.	AKR1C4 AKR1C2 AKR1C3	9.21e-08	4	100	3	17442338
Pubmed	Sensing of Bacterial Cyclic Dinucleotides by the Oxidoreductase RECON Promotes NF-κB Activation and Shapes a Proinflammatory Antibacterial State.	AKR1C4 AKR1C2 AKR1C3	9.21e-08	4	100	3	28329705
Pubmed	Characterization of 17alpha-hydroxysteroid dehydrogenase activity (17alpha-HSD) and its involvement in the biosynthesis of epitestosterone.	AKR1C4 AKR1C2 AKR1C3	9.21e-08	4	100	3	16018803
Pubmed	Reproductive phenotypes in mice with targeted disruption of the 20alpha-hydroxysteroid dehydrogenase gene.	AKR1C4 AKR1C2 AKR1C3	9.21e-08	4	100	3	17272929
Pubmed	Structure of the G225P/G226P mutant of mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21) ternary complex: implications for the binding of inhibitor and substrate.	AKR1C4 AKR1C2 AKR1C3	9.21e-08	4	100	3	19237748
Pubmed	Involvement of 20alpha-hydroxysteroid dehydrogenase in the maintenance of pregnancy in mice.	AKR1C4 AKR1C2 AKR1C3	9.21e-08	4	100	3	18667791
Pubmed	Mefenamic acid enhances anticancer drug sensitivity via inhibition of aldo-keto reductase 1C enzyme activity.	AKR1C4 AKR1C2 AKR1C3	9.21e-08	4	100	3	28259989
Pubmed	Stereospecific reduction of 5β-reduced steroids by human ketosteroid reductases of the AKR (aldo-keto reductase) superfamily: role of AKR1C1-AKR1C4 in the metabolism of testosterone and progesterone via the 5β-reductase pathway.	AKR1C4 AKR1C2 AKR1C3	9.21e-08	4	100	3	21521174
Pubmed	Molecular cloning of multiple cDNAs encoding human enzymes structurally related to 3 alpha-hydroxysteroid dehydrogenase.	AKR1C4 AKR1C2 AKR1C3	9.21e-08	4	100	3	8274401
Pubmed	Crystallization and preliminary X-ray diffraction analysis of mouse 3(17)alpha-hydroxysteroid dehydrogenase.	AKR1C4 AKR1C2 AKR1C3	9.21e-08	4	100	3	16511129
Pubmed	Identification of the oxidative 3alpha-hydroxysteroid dehydrogenase activity of rat Leydig cells as type II retinol dehydrogenase.	AKR1C4 AKR1C2 AKR1C3	9.21e-08	4	100	3	10803568
Pubmed	AKR1C1 alleviates LPS‑induced ALI in mice by activating the JAK2/STAT3 signaling pathway.	AKR1C4 AKR1C2 AKR1C3	9.21e-08	4	100	3	34590152
Pubmed	Localization of multiple human dihydrodiol dehydrogenase (DDH1 and DDH2) and chlordecone reductase (CHDR) genes in chromosome 10 by the polymerase chain reaction and fluorescence in situ hybridization.	AKR1C4 AKR1C2 AKR1C3	9.21e-08	4	100	3	7789999
Pubmed	Molecular cloning and characterization of mouse estradiol 17 beta-dehydrogenase (A-specific), a member of the aldoketoreductase family.	AKR1C4 AKR1C2 AKR1C3	2.30e-07	5	100	3	7737980
Pubmed	Retinaldehyde is a substrate for human aldo-keto reductases of the 1C subfamily.	AKR1C4 AKR1C2 AKR1C3	2.30e-07	5	100	3	21851338
Pubmed	Preterm birth without progesterone withdrawal in 15-hydroxyprostaglandin dehydrogenase hypomorphic mice.	AKR1C4 AKR1C2 AKR1C3	2.30e-07	5	100	3	17872381
Pubmed	Mouse 3alpha-hydroxysteroid dehydrogenase mRNA: a marker of lung maturity.	AKR1C4 AKR1C2 AKR1C3	2.30e-07	5	100	3	17064890
Pubmed	Close kinship of human 20alpha-hydroxysteroid dehydrogenase gene with three aldo-keto reductase genes.	AKR1C4 AKR1C2 AKR1C3	2.30e-07	5	100	3	10672042
Pubmed	Pregnane X receptor (PXR) deficiency promotes hepatocarcinogenesis via induction of Akr1c18 expression and prostaglandin F2α (PGF2α) levels.	AKR1C4 AKR1C2 AKR1C3	2.30e-07	5	100	3	38788959
Pubmed	Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis.	AKR1C4 AKR1C2 AKR1C3	2.30e-07	5	100	3	16984997
Pubmed	Down-regulation of neurosteroid biosynthesis in corticolimbic circuits mediates social isolation-induced behavior in mice.	AKR1C4 AKR1C2 AKR1C3	2.30e-07	5	100	3	18003893
Pubmed	The Gαq/11-provoked induction of Akr1c18 in murine luteal cells is mediated by phospholipase C.	AKR1C4 AKR1C2 AKR1C3	4.58e-07	6	100	3	29107092
Pubmed	Expression analysis of the aldo-keto reductases involved in the novel biosynthetic pathway of tetrahydrobiopterin in human and mouse tissues.	AKR1C4 AKR1C2 AKR1C3	4.58e-07	6	100	3	19273550
Pubmed	Quantitative appreciation of steroidogenic gene expression in mouse tissues: new roles for type 2 5alpha-reductase, 20alpha-hydroxysteroid dehydrogenase and estrogen sulfotransferase.	AKR1C4 AKR1C2 AKR1C3	4.58e-07	6	100	3	15860270
Pubmed	Regulation of progesterone levels during pregnancy and parturition by signal transducer and activator of transcription 5 and 20alpha-hydroxysteroid dehydrogenase.	AKR1C4 AKR1C2 AKR1C3	4.58e-07	6	100	3	15471942
Pubmed	MEF2 and NR2F2 cooperate to regulate Akr1c14 gene expression in mouse MA-10 Leydig cells.	AKR1C4 AKR1C2 AKR1C3	4.58e-07	6	100	3	26748576
Pubmed	Adrenal 20alpha-hydroxysteroid dehydrogenase in the mouse catabolizes progesterone and 11-deoxycorticosterone and is restricted to the X-zone.	AKR1C4 AKR1C2 AKR1C3	4.58e-07	6	100	3	17122075
Pubmed	Decidual prolactin silences the expression of genes detrimental to pregnancy.	AKR1C4 AKR1C2 AKR1C3	4.58e-07	6	100	3	17255200
Pubmed	The Steroidogenic Enzyme AKR1C3 Regulates Stability of the Ubiquitin Ligase Siah2 in Prostate Cancer Cells.	AKR1C4 AKR1C2 AKR1C3	8.01e-07	7	100	3	26160177
Pubmed	Aldo-ketoreductase 1c19 ablation does not affect insulin secretion in murine islets.	AKR1C4 AKR1C2 AKR1C3	8.01e-07	7	100	3	34843575
Pubmed	MicroRNA-200a serves a key role in the decline of progesterone receptor function leading to term and preterm labor.	AKR1C4 AKR1C2 AKR1C3	8.01e-07	7	100	3	22529366
Pubmed	A phosphodiesterase 11 (Pde11a) knockout mouse expressed functional but reduced Pde11a: Phenotype and impact on adrenocortical function.	AKR1C4 AKR1C2 AKR1C3	8.01e-07	7	100	3	33127481
Pubmed	17Beta-HSD type 5 expression and the emergence of differentiated epithelial Type II cells in fetal lung: a novel role for androgen during the surge of surfactant.	AKR1C4 AKR1C2 AKR1C3	8.01e-07	7	100	3	16337335
Pubmed	Androgen Receptor Is Dispensable for X-Zone Regression in the Female Adrenal but Regulates Post-Partum Corticosterone Levels and Protects Cortex Integrity.	AKR1C4 AKR1C2 AKR1C3	1.28e-06	8	100	3	33584538
Pubmed	Maternally expressed NLRP2 links the subcortical maternal complex (SCMC) to fertility, embryogenesis and epigenetic reprogramming.	NLRP7 NLRP2 DNMT3B	1.28e-06	8	100	3	28317850
Pubmed	Naturally occurring variants of human aldo-keto reductases with reduced in vitro metabolism of daunorubicin and doxorubicin.	AKR1C4 AKR1C2 AKR1C3	1.28e-06	8	100	3	20837989
Pubmed	Cloning of mouse 17beta-hydroxysteroid dehydrogenase type 2, and analysing expression of the mRNAs for types 1, 2, 3, 4 and 5 in mouse embryos and adult tissues.	AKR1C4 AKR1C2 AKR1C3	1.28e-06	8	100	3	9224647
Pubmed	Decrease in the T-box1 gene expression in embryonic brain and adult hippocampus of down syndrome mouse models.	AKR1C4 AKR1C2 AKR1C3	1.91e-06	9	100	3	33348080
Pubmed	Lack of placental neurosteroid alters cortical development and female somatosensory function.	AKR1C4 AKR1C2 AKR1C3	2.73e-06	10	100	3	36313771
Pubmed	Endogenous biotin as a marker of adrenocortical cells with steroidogenic potential.	AKR1C4 AKR1C2 AKR1C3	4.98e-06	12	100	3	21256921
Pubmed	Timing of adrenal regression controlled by synergistic interaction between Sf1 SUMOylation and Dax1.	AKR1C4 AKR1C2 AKR1C3	4.98e-06	12	100	3	28893949
Pubmed	A Novel Population of Inner Cortical Cells in the Adrenal Gland That Displays Sexually Dimorphic Expression of Thyroid Hormone Receptor-β1.	AKR1C4 AKR1C2 AKR1C3	4.98e-06	12	100	3	25774556
Pubmed	The Diet1 locus confers protection against hypercholesterolemia through enhanced bile acid metabolism.	AKR1C4 AKR1C2 AKR1C3	6.46e-06	13	100	3	11682476
Pubmed	Genetic determinants modulate susceptibility to pregnancy-associated tumourigenesis in a recombinant line of Min mice.	AKR1C4 AKR1C2 AKR1C3	6.46e-06	13	100	3	17062636
Pubmed	A link between lung androgen metabolism and the emergence of mature epithelial type II cells.	AKR1C4 AKR1C2 AKR1C3	6.46e-06	13	100	3	15117747
Pubmed	Ontogeny of adrenal-like glucocorticoid synthesis pathway and of 20α-hydroxysteroid dehydrogenase in the mouse lung.	AKR1C4 AKR1C2 AKR1C3	6.46e-06	13	100	3	24580729
Pubmed	Uncoupling endosomal CLC chloride/proton exchange causes severe neurodegeneration.	CLCN3 CLCN4	8.18e-06	2	100	2	32118314
Pubmed	NLRP2 controls age-associated maternal fertility.	NLRP7 NLRP2	8.18e-06	2	100	2	27881734
Pubmed	NLRP2 is highly expressed in a mouse model of ischemic stroke.	NLRP7 NLRP2	8.18e-06	2	100	2	27693696
Pubmed	Substrate specificity, gene structure, and tissue-specific distribution of multiple human 3 alpha-hydroxysteroid dehydrogenases.	AKR1C4 AKR1C3	8.18e-06	2	100	2	7650035
Pubmed	Structure-activity relationships of human AKR-type oxidoreductases involved in bile acid synthesis: AKR1D1 and AKR1C4.	AKR1D1 AKR1C4	8.18e-06	2	100	2	19013211
Pubmed	Local androgen inactivation in abdominal visceral adipose tissue.	AKR1C2 AKR1C3	8.18e-06	2	100	2	14671194
Pubmed	Reproductive Outcomes from Maternal Loss of Nlrp2 Are Not Improved by IVF or Embryo Transfer Consistent with Oocyte-Specific Defect.	NLRP7 NLRP2	8.18e-06	2	100	2	33090377
Pubmed	A genetic association study of NLRP2 and NLRP7 genes in idiopathic recurrent miscarriage.	NLRP7 NLRP2	8.18e-06	2	100	2	23360675
Pubmed	Preferential association with ClC-3 permits sorting of ClC-4 into endosomal compartments.	CLCN3 CLCN4	8.18e-06	2	100	2	28972156
Pubmed	Tensin Regulates Fundamental Biological Processes by Interacting with Integrins of Tonsil-Derived Mesenchymal Stem Cells.	TNS1 TNS3	8.18e-06	2	100	2	35954177
Pubmed	AKR1C2 and AKR1C3 expression in adipose tissue: Association with body fat distribution and regulatory variants.	AKR1C2 AKR1C3	8.18e-06	2	100	2	33675863
Pubmed	Arf guanine nucleotide-exchange factors BIG1 and BIG2 regulate nonmuscle myosin IIA activity by anchoring myosin phosphatase complex.	ARFGEF2 ARFGEF1	8.18e-06	2	100	2	23918382
Pubmed	Diagnostic and prognostic values of AKR1C3 and AKR1D1 in hepatocellular carcinoma.	AKR1D1 AKR1C3	8.18e-06	2	100	2	33493134
Pubmed	CDK activation by non-cyclin proteins.	SPDYE17 SPDYE6	8.18e-06	2	100	2	16488127
Pubmed	Regulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) and BIG2 activity via PKA and protein phosphatase 1gamma.	ARFGEF2 ARFGEF1	8.18e-06	2	100	2	17360629
Pubmed	Identification and localization of two brefeldin A-inhibited guanine nucleotide-exchange proteins for ADP-ribosylation factors in a macromolecular complex.	ARFGEF2 ARFGEF1	8.18e-06	2	100	2	10716990
Pubmed	Nlrp2, a maternal effect gene required for early embryonic development in the mouse.	NLRP7 NLRP2	8.18e-06	2	100	2	22295082
Pubmed	Established and novel Cdk/cyclin complexes regulating the cell cycle and development.	SPDYE17 SPDYE6	8.18e-06	2	100	2	21630153
Pubmed	Membrane association of the Arabidopsis ARF exchange factor GNOM involves interaction of conserved domains.	ARFGEF2 ARFGEF1	8.18e-06	2	100	2	18203920
Pubmed	Suppressing NLRP2 expression accelerates hepatic steatosis: A mechanism involving inflammation and oxidative stress.	NLRP7 NLRP2	8.18e-06	2	100	2	30454891
Pubmed	NLRP2 inflammasome in dorsal root ganglion as a novel molecular platform that produces inflammatory pain hypersensitivity.	NLRP7 NLRP2	8.18e-06	2	100	2	31162334
Pubmed	Purification and cloning of a brefeldin A-inhibited guanine nucleotide-exchange protein for ADP-ribosylation factors.	ARFGEF2 ARFGEF1	8.18e-06	2	100	2	10212200
Pubmed	Molecular characterization of a novel gene family (PHTF) conserved from Drosophila to mammals.	PHTF2 PHTF1	8.18e-06	2	100	2	10729229
Pubmed	Isolation and characterization of cloned cDNAs encoding human liver chlordecone reductase.	AKR1C4 AKR1C2	8.18e-06	2	100	2	2187532
Pubmed	Redundant roles of BIG2 and BIG1, guanine-nucleotide exchange factors for ADP-ribosylation factors in membrane traffic between the trans-Golgi network and endosomes.	ARFGEF2 ARFGEF1	8.18e-06	2	100	2	18417613
Pubmed	Shh signaling regulates adrenocortical development and identifies progenitors of steroidogenic lineages.	AKR1C4 AKR1C2 AKR1C3	8.20e-06	14	100	3	19955443
Pubmed	Placental endocrine function shapes cerebellar development and social behavior.	AKR1C4 AKR1C2 AKR1C3	8.20e-06	14	100	3	34400844
Pubmed	Targeted Disruption of Lats1 and Lats2 in Mice Impairs Adrenal Cortex Development and Alters Adrenocortical Cell Fate.	AKR1C4 AKR1C2 AKR1C3	1.52e-05	17	100	3	32243503
Pubmed	Functional dynamics of H3K9 methylation during meiotic prophase progression.	AKR1C4 AKR1C2 AKR1C3	2.16e-05	19	100	3	17599069
Pubmed	Distinct expression patterns of ICK/MAK/MOK protein kinases in the intestine implicate functional diversity.	MAK CILK1	2.45e-05	3	100	2	24244486
Pubmed	Aldo-keto reductase 1C subfamily genes in skin are UV-inducible: possible role in keratinocytes survival.	AKR1C2 AKR1C3	2.45e-05	3	100	2	19320734
Pubmed	Mosaic moles and non-familial biparental moles are not caused by mutations in NLRP7, NLRP2 or C6orf221.	NLRP7 NLRP2	2.45e-05	3	100	2	22909446
Interaction	AKR1C1 interactions	AKR1D1 AKR1C4 AKR1C2 AKR1C3	1.42e-06	20	86	4	int:AKR1C1
Interaction	AKR1C4 interactions	AKR1C4 AKR1C2 AKR1C3	4.14e-06	8	86	3	int:AKR1C4
Interaction	AKR1C3 interactions	AKR1D1 AKR1C4 AKR1C2 AKR1C3	1.83e-05	37	86	4	int:AKR1C3
Cytoband	Ensembl 112 genes in cytogenetic band chr7q11	SPDYE17 SPDYE10 PHTF2 SPDYE9 SPDYE18 SPDYE12 SPDYE11 SPDYE13 SPDYE15 SPDYE8 SPDYE21 SPDYE5 SPDYE14 SPDYE16	1.67e-15	271	102	14	chr7q11
Cytoband	7q11.23	SPDYE10 SPDYE9 SPDYE18 SPDYE8 SPDYE5 SPDYE14	8.70e-08	97	102	6	7q11.23
Cytoband	10p15-p14	AKR1C2 AKR1C3	7.29e-05	6	102	2	10p15-p14
Cytoband	7q22.1	SPDYE3 SPDYE2 SPDYE2B SPDYE6	1.23e-04	113	102	4	7q22.1
Cytoband	Ensembl 112 genes in cytogenetic band chr10p15	AKR1C4 AKR1C2 AKR1C3	1.09e-03	90	102	3	chr10p15
Cytoband	Ensembl 112 genes in cytogenetic band chr7q22	SPDYE3 SPDYE2 SPDYE2B SPDYE6	1.49e-03	219	102	4	chr7q22
Cytoband	5p15.2	SEMA5A DNAH5	1.65e-03	27	102	2	5p15.2
Cytoband	20q13.13	ARFGEF2 PREX1	2.32e-03	32	102	2	20q13.13
GeneFamily	Speedy/RINGO cell cycle regulator family	SPDYE1 SPDYE9 SPDYE3 SPDYE2 SPDYE8 SPDYE5 SPDYE2B SPDYE6	5.86e-18	12	62	8	756
GeneFamily	Aldo-keto reductases	AKR1D1 AKR1C4 AKR1C2 AKR1C3	1.66e-07	15	62	4	399
GeneFamily	WD repeat domain containing	NBEAL1 WDR46 SEC31A WDR38 DAW1 WDFY3 PAK1IP1 HERC1 WDR17	2.55e-07	262	62	9	362
GeneFamily	EF-hand domain containing\|Spectrins	SPTBN2 SPTBN5	2.40e-04	7	62	2	1113
GeneFamily	DNAJ (HSP40) heat shock proteins\|C2 tensin-type domain containing	TNS1 TNS3	3.20e-04	8	62	2	837
GeneFamily	WD repeat domain containing\|BEACH domain containing	NBEAL1 WDFY3	4.10e-04	9	62	2	1230
GeneFamily	Chloride voltage-gated channels	CLCN3 CLCN4	5.12e-04	10	62	2	302
GeneFamily	Pyrin domain containing\|Pyrin and HIN domain family	NLRP7 NLRP2	3.30e-03	25	62	2	994
GeneFamily	NLR family	NLRP7 NLRP2	3.30e-03	25	62	2	666
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	DMTF1 ZKSCAN2	1.43e-02	53	62	2	532
Coexpression	GSE22886_NAIVE_TCELL_VS_NEUTROPHIL_DN	STAM2 MAK UPB1 CLCN4 RNF141 TNS1 MUSK	8.22e-06	199	95	7	M4474
Coexpression	IVANOVA_HEMATOPOIESIS_STEM_CELL_LONG_TERM	CILK1 ZKSCAN2 AKR1C4 ZNF467 AKR1C2 AKR1C3 TNS1	1.98e-05	228	95	7	MM1014
Coexpression	HALLMARK_PROTEIN_SECRETION	ARFGEF2 ARFGEF1 SEC31A CLCN3 ZW10	2.65e-05	96	95	5	M5910
Coexpression	IRITANI_MAD1_TARGETS_UP	AKR1C4 AKR1C2 AKR1C3	3.02e-05	17	95	3	MM826
Coexpression	NAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_UP	DMTF1 STAM2 ARFGEF2 ATP9B SEC31A PFKFB2 TRIP11 SH3GLB1 CLCN3 UBTF TBC1D1 AACS SUZ12 TDP1 PHTF1	3.04e-05	1215	95	15	M41122
Coexpression	LAKE_ADULT_KIDNEY_C26_MESANGIAL_CELLS	NBEAL1 PHTF2 TBC1D1 HERC1 TNS1 TNS3	4.60e-05	177	95	6	M39245
ToppCell	LPS-IL1RA-Unknown-Endothelial\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BRIP1 SPTBN2 AKR1C2 WDR17 NOTCH3	5.76e-06	118	96	5	aefad0b35aff980b6a2a98057735442e8a65ab04
ToppCell	LPS-IL1RA-Unknown\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BRIP1 SPTBN2 AKR1C2 WDR17 NOTCH3	5.76e-06	118	96	5	6cb4063b83f867b782080ce5b1199b51bb277f2a
ToppCell	droplet-Liver-LIVER_NPC-30m-Epithelial-Hepatocyte_(Midlobular)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AMT UPB1 AKR1D1 TSTD3 TTLL13	1.28e-05	139	96	5	e363c69b58cff8571ca75b91a3d052f9cbccac27
ToppCell	5'-Adult-Appendix-Hematopoietic-Myeloid-Lymphoid_DC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAK ADAM12 VWDE NAV1 ZNF85	3.09e-05	167	96	5	8b223333c0c7a85b5a1af6f2f5b12ee0d94357f6
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	ARFGEF1 ZKSCAN2 PLEKHH1 FAIM CLCN4	3.36e-05	170	96	5	09bcbc7eb3b1d35cf03f01ce2f2fe37373382dd4
ToppCell	COVID-19-kidney-REN+Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NBEAL1 PHTF2 ADAM12 TBC1D1 NOTCH3	3.76e-05	174	96	5	8393f0b43c767839c1630bcb952d62b42efc788d
ToppCell	Ciliated_cells-B-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	CFAP95 MAK WDR38 DAW1 PLG	5.29e-05	187	96	5	bc1f33f332ac939c2425f510173430ca2ba0c3ee
ToppCell	facs-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFAP95 MAK DAW1 ATP2C2 DNAH5	5.85e-05	191	96	5	649fcb62ad15de2f83e61591e43923a717664ae7
ToppCell	BAL-Control-Epithelial-Epithelial-Ciliated\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CFAP95 WDR38 DAW1 ATP2C2 DNAH5	5.85e-05	191	96	5	7b5da29109aa28768c67653a1bc0f385c2d2269b
ToppCell	facs-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFAP95 MAK DAW1 ATP2C2 DNAH5	5.85e-05	191	96	5	9621e22e14ea069f22713947c9faa2d882abe5fe
ToppCell	BAL-Control-Epithelial\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CFAP95 WDR38 DAW1 ATP2C2 DNAH5	5.85e-05	191	96	5	9f19098f260d5542aa8ba7eb6f91b44d0db6e0a4
ToppCell	BAL-Control-Epithelial-Epithelial-Ciliated-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CFAP95 WDR38 DAW1 ATP2C2 DNAH5	5.85e-05	191	96	5	fa9f8b50bfc7911c858bc2f9dcd204873d97ac61
ToppCell	Control-Epithelial-Ciliated_cells\|Control / Condition, Lineage and Cell class	CFAP95 WDR38 DAW1 ATP2C2 DNAH5	5.85e-05	191	96	5	ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCell	Healthy_Control-Epithelial-Epithelial-\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	CFAP95 WDR38 DAW1 ATP2C2 DNAH5	5.85e-05	191	96	5	28caedb2e448e0c7f494100d714fa7cdcf150691
ToppCell	BAL-Control-Epithelial-Epithelial-Ciliated-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CFAP95 WDR38 DAW1 ATP2C2 DNAH5	5.85e-05	191	96	5	b4e335e798c9617356b8e24412f9270c42dce656
ToppCell	BAL-Control-Epithelial-Epithelial-Ciliated\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CFAP95 WDR38 DAW1 ATP2C2 DNAH5	5.85e-05	191	96	5	c4b223b33c020a064f576711a3d700eb60a2d737
ToppCell	BAL-Control-Epithelial\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CFAP95 WDR38 DAW1 ATP2C2 DNAH5	5.85e-05	191	96	5	5129f778a9283bfac4ff322c21c5ca71da4b7174
ToppCell	BAL-Control-Epithelial-Epithelial\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CFAP95 WDR38 DAW1 ATP2C2 DNAH5	5.85e-05	191	96	5	df8a1a6e78aa0cb941b94cb676bd6891d79f3687
ToppCell	Healthy_Control-Epithelial-Epithelial\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	CFAP95 WDR38 DAW1 ATP2C2 DNAH5	5.85e-05	191	96	5	15b9386b26caaa7d15f704c4a18881e1ce918a21
ToppCell	Control-Epithelial\|Control / Disease group,lineage and cell class （2021.01.30）	CFAP95 WDR38 DAW1 ATP2C2 DNAH5	5.85e-05	191	96	5	b78547dae8328244a47c83346447bdd787efbcae
ToppCell	Healthy_Control-Epithelial\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	CFAP95 WDR38 DAW1 ATP2C2 DNAH5	5.85e-05	191	96	5	fdcdadbfc9ccae175abe4de8c7428ac4f6a67fde
ToppCell	BAL-Control-Epithelial-Epithelial\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CFAP95 WDR38 DAW1 ATP2C2 DNAH5	5.85e-05	191	96	5	c50d6a1a6209ed4157f7c00fc24d4ecb43790f44
ToppCell	Control-Epithelial-Ciliated\|Control / Disease group,lineage and cell class （2021.01.30）	CFAP95 WDR38 DAW1 ATP2C2 DNAH5	5.85e-05	191	96	5	cdc08e95a0c8f5c7a8d01b6bbaafdb54ef2f0d12
ToppCell	Control-Epithelial\|Control / Condition, Lineage and Cell class	CFAP95 WDR38 DAW1 ATP2C2 DNAH5	5.85e-05	191	96	5	6228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	NBEAL1 TRIP11 SUZ12 WDFY3 EIF2AK2	6.14e-05	193	96	5	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	Children_(3_yrs)-Immune-monocyte-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DOCK2 SIRPB2 TBC1D1 NAV1 PREX1	6.45e-05	195	96	5	81a28289eda1a8a1a31b7357106f64ac5000e172
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARFGEF1 SEC31A PFKFB2 TRIP11 HERC1	6.45e-05	195	96	5	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	severe-Myeloid-Neutrophils_4\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	PFKFB2 ZNF467 RNF141 WDFY3 PREX1	7.10e-05	199	96	5	50242666def13e5d4149c563ae000d6768f086f7
ToppCell	LPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	CFAP95 WDR38 DAW1 ATP2C2 DNAH5	7.27e-05	200	96	5	96701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCell	LPS_IL1RA_TNF-Epithelial_airway-airway_epithelial\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	CFAP95 WDR38 ATP2C2 AKR1C3 DNAH5	7.27e-05	200	96	5	da12821e8a0657869ca0f75d351cce2d7605a505
ToppCell	severe-Myeloid-Neutrophils_4\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	PFKFB2 ZNF467 RNF141 WDFY3 PREX1	7.27e-05	200	96	5	b665f36dcf3c9d3981ee96f2973512f751612542
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Mesenchymal\|3m / Sample Type, Dataset, Time_group, and Cell type.	CFAP95 MAK WDR38 DAW1 MUSK	7.27e-05	200	96	5	ce012d738cbec1afdd6af0e10e94b2b6c17b036e
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Mesenchymal-Cilia-bearing_cell\|3m / Sample Type, Dataset, Time_group, and Cell type.	CFAP95 MAK WDR38 DAW1 MUSK	7.27e-05	200	96	5	0d14a950172a56b11fdebee8f4e13b0c10e0d592
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-Cilia-bearing_cell\|6m / Sample Type, Dataset, Time_group, and Cell type.	CFAP95 MAK WDR38 DAW1 DNAH5	7.27e-05	200	96	5	177f9ad8dd8635394c575a2b30140184df0bd51e
ToppCell	LPS_IL1RA_TNF-Epithelial_airway\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	CFAP95 WDR38 ATP2C2 AKR1C3 DNAH5	7.27e-05	200	96	5	72c1d9eeaed4b3ee6b6c602e8aa29efc2e8744eb
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Vip_Itih5\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DOCK2 ADAM12 TNS1 TNS3	1.16e-04	116	96	4	605bd4fdf547cc41783e99cd78425760ef6461ef
ToppCell	LPS-IL1RA-Unknown-Endothelial-Pericyte_2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BRIP1 SPTBN2 WDR17 NOTCH3	1.55e-04	125	96	4	2938a1d62afe1e0a3abba5eb92f07b886cc0accd
ToppCell	droplet-Liver-LIVER_NPC-30m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AMT UPB1 AKR1D1 TSTD3	2.39e-04	140	96	4	39083c3e288d1878fdc4c798e600fb156daff8a9
ToppCell	droplet-Liver-LIVER_NPC-30m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AMT UPB1 AKR1D1 TSTD3	2.39e-04	140	96	4	06e14a375ea85175c809ff5a0ea16e865ccb4ad5
ToppCell	mild_COVID-19_(asymptomatic)-Treg\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	ZFP30 ADAM12 FAIM SPDYE16	2.73e-04	145	96	4	2d0903009e918500facfd017ff31f2cec1e76131
ToppCell	Ciliated_cells-B-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	MAK ADAM12 WDR38 PLG	3.03e-04	149	96	4	6399c5a2f06d79f020dece252526f1c0c110d569
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SIRPB2 ZNF467 UBTF NAV1	3.03e-04	149	96	4	a85a051e0d82430160967e72fa04b55f43e84513
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SIRPB2 ZNF467 UBTF NAV1	3.11e-04	150	96	4	7a381f5ae94eba5eb60dcbf83416b4eb18c279ea
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA5A DAW1 DNAH5 NOTCH3	3.27e-04	152	96	4	d5ba87b5d34e52cef8475befafea962d70fa8a1d
ToppCell	droplet-Liver-LIVER_HEPATOCYTES\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA5A DAW1 DNAH5 NOTCH3	3.27e-04	152	96	4	d88d68a788a3256671ebbc06e104833f1f58f07d
ToppCell	Control-Epithelial_airway-Ciliated_cells-Ciliated\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAK DAW1 ATP2C2 DNAH5	3.43e-04	154	96	4	4e3bc24043144143842627cacf6f90dda2228910
ToppCell	Control-Epithelial_airway-Ciliated_cells\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAK DAW1 ATP2C2 DNAH5	3.43e-04	154	96	4	7556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_E\|390C / Donor, Lineage, Cell class and subclass (all cells)	ZKSCAN2 EIF2AK2 PREX1 PGBD4	3.52e-04	155	96	4	98d8432739965dd1ab77c899cb6321f7f05eaa46
ToppCell	Influenza_Severe-Neutrophil\|Influenza_Severe / Disease group and Cell class	MAK PFKFB2 PLEKHH1 WDFY3	4.06e-04	161	96	4	98c95b1b85d5427415af2ca8fb14849e97f6e8b5
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	BRIP1 ADAM12 PLG DNAH5	4.26e-04	163	96	4	e4077e587895c85bc806be05ff5d451088e39468
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_bronchial_vessel-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	UPB1 FAIM TSTD3 LTV1	4.56e-04	166	96	4	a697460dfe72e08fbf7d8e734a16b7dd2c6d86f9
ToppCell	15-Distal-Epithelial-Multiciliated_precursor\|Distal / Age, Tissue, Lineage and Cell class	CFAP95 WDR38 DAW1 DNAH5	4.66e-04	167	96	4	442ea71a581ed5a547a214132b9f1b0243fd0895
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA5A ANKRD6 DAW1 DNAH5	4.66e-04	167	96	4	cf6206c506715cd846799c62cf7c06e3fa99f7af
ToppCell	Children_(3_yrs)-Immune-enucleated_erythrocyte-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	UPB1 FAAP100 OTOGL ZMYM3	4.77e-04	168	96	4	8f0c4dfad9f6fed9dcc31795abfe77758ceb46a1
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Sgol2a_(Very_small_cluster)\|Striatum / BrainAtlas - Mouse McCarroll V32	ZKSCAN2 TRIP11 WDR38 PAK1IP1	4.88e-04	169	96	4	c3bf0cb67f200d02d5a021754e9b2a68d23ea168
ToppCell	mild_COVID-19_(asymptomatic)-RBC\|World / disease group, cell group and cell class (v2)	AMT TRIP11 ZNF85 TDP1	4.88e-04	169	96	4	2bda6ab3f32e05cb7daf91eb7c39b4fcc9ae91bb
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Sgol2a_(Very_small_cluster)--\|Striatum / BrainAtlas - Mouse McCarroll V32	ZKSCAN2 TRIP11 WDR38 PAK1IP1	4.88e-04	169	96	4	5375eb52ebadccb7bfff997a11985f23e81014d6
ToppCell	Influenza_Severe-Neutrophil\|World / Disease group and Cell class	MAK PFKFB2 PLEKHH1 WDFY3	4.88e-04	169	96	4	6e8e2580e19c96bcf7fa6a6d8c183df65f428396
ToppCell	droplet-Marrow-nan-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAOA TRIP11 NAV1 EIF2AK2	4.88e-04	169	96	4	5f5bec13208f4c3b6eacbba180c8a6402743b76e
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA5A ANKRD6 DAW1 DNAH5	4.88e-04	169	96	4	30141f76e9bfc2b4586429857c72dbc85ba65cc9
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Sgol2a_(Very_small_cluster)-\|Striatum / BrainAtlas - Mouse McCarroll V32	ZKSCAN2 TRIP11 WDR38 PAK1IP1	4.88e-04	169	96	4	1c132d21255f5a5174ac38db4e91927f9093418e
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-mLTo\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEMA5A ADAM12 OTOGL NOTCH3	4.88e-04	169	96	4	559e98216720e4babf0b0941100f1b485c35b11b
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAM12 OTOGL WDR17 NOTCH3	4.99e-04	170	96	4	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BRIP1 ADAM12 AACS LTV1	4.99e-04	170	96	4	b1a16600754e0c12f7d39c9221f1b03135833f16
ToppCell	droplet-Pancreas-Exocrine-18m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAK SEMA5A DNAH5 TNS1	5.10e-04	171	96	4	5447b78148f7bccb727e2fc108589b2af02a5d31
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-Deuterosomal\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CFAP95 WDR38 DAW1 DNAH5	5.21e-04	172	96	4	08ad76412c9cc3504141797b44b88478ced87476
ToppCell	droplet-Pancreas-Exocrine-18m-Epithelial-pancreatic_ductal_cel\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAK SEMA5A DNAH5 TNS1	5.21e-04	172	96	4	a7eee0a30d2fe20c865a07b9004c6a821a72c0c4
ToppCell	droplet-Pancreas-Exocrine-18m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAK SEMA5A DNAH5 TNS1	5.21e-04	172	96	4	0a9fe2cd28203970295a1288078c66eadac1c9ed
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_1\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	DOCK2 ARFGEF2 ADAM12 FAAP100	5.32e-04	173	96	4	efb8072475000888efe088d00e870c56ffad4172
ToppCell	PCW_10-12-Epithelial-Epithelial_ciliated\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CFAP95 WDR38 DAW1 DNAH5	5.44e-04	174	96	4	b8d1c556290d188f56aeefc17f03119686945fe7
ToppCell	TCGA-Liver\|World / Sample_Type by Project: Shred V9	UPB1 AKR1D1 AKR1C4 PLG	5.44e-04	174	96	4	452932f08cf53e5949672a025d78cecb874aa4b0
ToppCell	PCW_10-12-Epithelial-Epithelial_ciliated-epi_ciliated_(14)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CFAP95 WDR38 DAW1 DNAH5	5.44e-04	174	96	4	00cf27bc23af1472a507be31fba6245a8fdd901b
ToppCell	PCW_13-14-Epithelial-Epithelial_ciliated\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CFAP95 WDR38 DAW1 DNAH5	5.56e-04	175	96	4	b1369d2b74f461e6822d0c33e9b50fe0dfbceb54
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NBEAL1 OTOGL TBC1D1 NOTCH3	5.56e-04	175	96	4	316f2ea930437bf1243b1c0f45e6bd864112c6f2
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NBEAL1 OTOGL TBC1D1 NOTCH3	5.56e-04	175	96	4	a9f08e1e4c2997dcdd3e5d92daac480da19100b8
ToppCell	PCW_13-14-Epithelial-Epithelial_ciliated-epi_ciliated_(14)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CFAP95 WDR38 DAW1 DNAH5	5.56e-04	175	96	4	c82ec6deb6ccdd991a69a62b6d62d5b14c803d7a
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-RGCs_early_2\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	CFAP95 AKR1C4 WDR38 DAW1	5.68e-04	176	96	4	8e0ac3ad5e47614b4befabd674a40e3eaae553f3
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP95 WDR38 DAW1 NOTCH3	5.80e-04	177	96	4	e8bb4f8ecd5e283efec966b9fc2040a6152d5551
ToppCell	droplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAK TBC1D1 WDFY3 PREX1	5.80e-04	177	96	4	14fb8d182775dfd0e49aa7e4e12543a85b3b8bd6
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DPY19L1 SEMA5A ANKRD6 ATP2C2	5.93e-04	178	96	4	431e7557b8e8764e16e9e48368ce6bfa3c61561a
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP95 MAK WDR38 DNAH5	5.93e-04	178	96	4	58857bb8c13e0e1c6d9f5c1258f00fff62063d68
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP95 MAK WDR38 DNAH5	5.93e-04	178	96	4	8b7df6ab8709d9ab9dff97677cc4561aec2745bc
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP95 MAK WDR38 DNAH5	5.93e-04	178	96	4	b0baf5667e3301898b3e45e974b8a8530af6a338
ToppCell	COVID-19-kidney-vSMC/Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NBEAL1 TBC1D1 TNS1 NOTCH3	6.05e-04	179	96	4	111b1084f73306bdeffaaf240e7dbb4f5bf33de1
ToppCell	10x5'v1-week_17-19-Hematopoietic-erythroid-early_erythroid\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	AMT SPTBN2 VWDE AKR1C3	6.05e-04	179	96	4	3f73f89905c061ada4e3eb921fa394d95f95c959
ToppCell	LA-01._Fibroblast_I\|LA / Chamber and Cluster_Paper	AKR1C2 NAV1 TBX20 MUSK	6.05e-04	179	96	4	dcb6ec9ae72b13fe388b72dace2815293fafe8ee
ToppCell	Ciliated_cells-A-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	CFAP95 WDR38 DAW1 DNAH5	6.18e-04	180	96	4	d9be152773fe9f2160edad9246fa03c03afeafd6
ToppCell	10x5'-lymph-node_spleen-Myeloid_Mac-Cycling_Myeloid-Mac\|lymph-node_spleen / Manually curated celltypes from each tissue	SIRPB2 WDFY3 NOTCH3 TNS3	6.18e-04	180	96	4	4eea8366cdb82c356325ce88f09ad8b302c17a07
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DPY19L1 SEMA5A TBC1D1 ATP2C2	6.18e-04	180	96	4	e8841ef1239f9ee73ac4f4e11faca0742694f368
ToppCell	368C-Epithelial_cells-Epithelial-F_(Ciliated)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	CFAP95 WDR38 DAW1 DNAH5	6.31e-04	181	96	4	5a4574f1bfd0b4ca78da7effda43420857e17296
ToppCell	Thalamus-Macroglia\|Thalamus / BrainAtlas - Mouse McCarroll V32	TRIM59 STXBP3 PREX1 TNS3	6.31e-04	181	96	4	4f62b63854a4e9fea6e839f0340e78392c66fb0e
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SEMA5A OTOGL TNS1 NOTCH3	6.31e-04	181	96	4	451b87ac95154bb80018b8dd245b4a6389d81411
ToppCell	RA-07._Pericyte\|RA / Chamber and Cluster_Paper	UPB1 NBEAL1 SEMA5A NOTCH3	6.31e-04	181	96	4	8dfb42d096db6c2df9b41303a7199d134d4bff07
ToppCell	droplet-Liver-nan-3m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPY19L1 CILK1 ZKSCAN2 NAV1	6.31e-04	181	96	4	fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_CCL3+-Alveolar_macrophage_CCL3+_L.1.0.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DOCK2 DCUN1D5 NLRP2 ZW10	6.31e-04	181	96	4	a8d4b2340d99734bf9379b467fb481c598b9b4fb
ToppCell	368C-Epithelial_cells-Epithelial-F_(Ciliated)\|368C / Donor, Lineage, Cell class and subclass (all cells)	CFAP95 WDR38 DAW1 DNAH5	6.31e-04	181	96	4	a4e891603645f694687e68e585744ddc1a3c8697
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-Ciliated\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CFAP95 WDR38 DAW1 DNAH5	6.31e-04	181	96	4	8eed9d46d924b16f6dd1a025ff612244b02b4391
ToppCell	RA-07._Pericyte\|World / Chamber and Cluster_Paper	UPB1 NBEAL1 SEMA5A NOTCH3	6.44e-04	182	96	4	2075efeae633550fb2eb026d0dfd741c8252482e
ToppCell	Ciliated_cells-B-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	CFAP95 MAK WDR38 DNAH5	6.44e-04	182	96	4	e44c4810dc7d51a76b86d7623f8e4c4d8b4bf2fc
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TRIM59 PLEKHH1 PREX1 MUSK	6.57e-04	183	96	4	5472cdce6d99314d229418412acf1fff6340db7d
Drug	flunisolide	AKR1D1 AKR1C4 AKR1C2 AKR1C3	1.66e-07	13	91	4	ctd:C007734
Drug	5-alpha-Dihydroprogesterone	AKR1D1 AKR1C4 AKR1C2 AKR1C3	2.32e-07	14	91	4	ctd:D043582
Drug	cloxazolam	AKR1C4 AKR1C2 AKR1C3	2.46e-07	4	91	3	ctd:C005522
Drug	Pregnanes	AKR1C4 AKR1C2 AKR1C3	2.46e-07	4	91	3	ctd:D011278
Drug	tetralol	AKR1C4 AKR1C2 AKR1C3	2.46e-07	4	91	3	ctd:C019106
Drug	3',3'',5',5''-tetrabromophenolphthalein	AKR1C4 AKR1C2 AKR1C3	2.46e-07	4	91	3	ctd:C018156
Drug	Hydroxysteroids	AKR1C4 AKR1C2 AKR1C3	6.14e-07	5	91	3	ctd:D006914
Drug	cresolphthalein	AKR1C4 AKR1C2 AKR1C3	6.14e-07	5	91	3	ctd:C010092
Drug	3-hydroxyhexobarbital	AKR1C4 AKR1C2 AKR1C3	1.22e-06	6	91	3	CID000439898
Drug	Medazepam	AKR1C4 AKR1C2 AKR1C3	1.22e-06	6	91	3	ctd:D008472
Drug	2-cyclohexen-1-ol	AKR1C4 AKR1C2 AKR1C3	3.41e-06	8	91	3	CID000013198
Drug	Nitrazepam	AKR1C4 AKR1C2 AKR1C3	3.41e-06	8	91	3	ctd:D009567
Drug	4-hydroxybenzoic acid	AKR1C4 AKR1C2 AKR1C3	5.10e-06	9	91	3	ctd:C038193
Drug	20-alpha-Dihydroprogesterone	AKR1C4 AKR1C2 AKR1C3	5.10e-06	9	91	3	ctd:D004092
Drug	octyl gallate	AKR1C4 AKR1C2 AKR1C3	7.26e-06	10	91	3	ctd:C016627
Drug	Dihydroxydihydrobenzopyrenes	AKR1C4 AKR1C2 AKR1C3	9.96e-06	11	91	3	ctd:D004101
Drug	chlordecone alcohol	AKR1C4 AKR1C2 AKR1C3	9.96e-06	11	91	3	CID000013946
Drug	Phenolphthalein	AKR1C4 AKR1C2 AKR1C3	1.32e-05	12	91	3	ctd:D020113
Drug	Atovaquone [95233-18-4]; Down 200; 11uM; MCF7; HT_HG-U133A	STAM2 BRIP1 ARFGEF2 PHTF2 CILK1 STXBP3 RNF141	1.38e-05	196	91	7	4786_DN
Drug	Proparacaine hydrochloride [5875-06-9]; Down 200; 12uM; HL60; HT_HG-U133A	ATP9B ANKRD6 CLCN3 CLCN4 UBTF TNS1 DNMT3B	1.38e-05	196	91	7	3113_DN
Drug	beta- Belladonnine dichloroethylate [191355-47-2]; Down 200; 6uM; PC3; HT_HG-U133A	STAM2 AMT PHTF2 ANKRD6 ADAM12 CLCN4 UBTF	1.38e-05	196	91	7	6638_DN
Drug	Nomifensine maleate [32795-47-4]; Up 200; 11.2uM; MCF7; HT_HG-U133A	MAK MAOA SPTBN2 PHTF2 ADAM12 PLG NOTCH3	1.43e-05	197	91	7	7217_UP
Drug	C75; Up 200; 10uM; PC3; HT_HG-U133A	AMT ARFGEF2 ADAM12 CLCN3 CLCN4 TNS1 PHTF1	1.48e-05	198	91	7	6428_UP
Drug	Ethynylestradiol 3-methyl ether [72-33-3]; Down 200; 12.8uM; MCF7; HT_HG-U133A	STAM2 BRIP1 ARFGEF2 CILK1 DCUN1D4 FAIM TNS3	1.48e-05	198	91	7	4792_DN
Drug	Clozapine [5786-21-0]; Down 200; 12.2uM; PC3; HT_HG-U133A	STAM2 ATG13 ZFP30 PHTF2 SEMA5A PFKFB2 CLCN4	1.53e-05	199	91	7	4670_DN
Drug	Benzocaine [94-09-7]; Up 200; 24.2uM; HL60; HT_HG-U133A	STAM2 MAOA ATP9B AKR1C4 ANKRD6 TRIP11 NOTCH3	1.58e-05	200	91	7	2167_UP
Drug	rosiglitazone; Down 200; 10uM; HL60; HT_HG-U133A	AMT UPB1 ATG13 CILK1 TRIP11 CLCN4 WDFY3	1.58e-05	200	91	7	6192_DN
Drug	C05473	AKR1D1 AKR1C4	1.58e-05	2	91	2	CID000440694
Drug	NSC79098	AKR1D1 AKR1C4	1.58e-05	2	91	2	CID000254632
Drug	baccharin	AKR1C2 AKR1C3	1.58e-05	2	91	2	ctd:C012764
Drug	DMBA-3,4-dihydrodiol	AKR1C4 AKR1C2 AKR1C3	1.72e-05	13	91	3	CID000050096
Drug	o-quinone	AKR1C4 AKR1C2 CLCN4 AKR1C3	2.16e-05	41	91	4	CID000011421
Drug	1-acenaphthenol	AKR1C4 AKR1C2 AKR1C3	2.18e-05	14	91	3	CID000022750
Drug	Meclofenamic Acid	AKR1C4 AKR1C2 AKR1C3	2.18e-05	14	91	3	ctd:D008469
Drug	AC1L99QZ	AKR1D1 AKR1C4	4.73e-05	3	91	2	CID000440678
Drug	cyclopentanol	AKR1C2 AKR1C3	4.73e-05	3	91	2	ctd:C016327
Drug	cyclopentanone	AKR1C2 AKR1C3	4.73e-05	3	91	2	ctd:C007201
Drug	5-dihydrodeoxycorticosterone	AKR1C4 AKR1C2	4.73e-05	3	91	2	ctd:C454687
Drug	4-benzoylbenzoic acid	AKR1C2 AKR1C3	4.73e-05	3	91	2	ctd:C058818
Drug	dichloro(4-cymene)ruthenium(II)	AKR1C2 AKR1C3	4.73e-05	3	91	2	ctd:C530610
Drug	1 C2	MAOA AKR1C4 NLRP2 AKR1C2 AKR1C3	5.10e-05	100	91	5	CID005327152
Drug	androstane-3,17-dione	AKR1D1 AKR1C4 AKR1C2 AKR1C3	5.17e-05	51	91	4	CID000000443
Drug	Hydrocortisone	MAOA AKR1D1 AKR1C4 ADAM12 AKR1C2 AKR1C3	5.67e-05	167	91	6	ctd:D006854
Drug	oxcarbazepine	AKR1C4 AKR1C2 AKR1C3	5.71e-05	19	91	3	ctd:C036006
Drug	benzo(a)pyrene-7,8-dione	AKR1C4 AKR1C2 AKR1C3	6.70e-05	20	91	3	ctd:C076588
Drug	Chrysenes	AKR1C4 AKR1C2 AKR1C3	6.70e-05	20	91	3	ctd:D002911
Drug	catechol	MAOA AKR1C4 NLRP2 AKR1C2 TBC1D1 AKR1C3 DNAH5	7.77e-05	257	91	7	CID000000289
Drug	Flunitrazepam	AKR1C4 AKR1C2 AKR1C3	7.80e-05	21	91	3	ctd:D005445
Drug	benzene dihydrodiol	AKR1C4 AKR1C2 AKR1C3	9.00e-05	22	91	3	CID000000418
Drug	Sid 7808	AKR1D1 AKR1C4	9.43e-05	4	91	2	CID000000140
Drug	tetrahydrodeoxycorticosterone	AKR1C4 AKR1C2	9.43e-05	4	91	2	ctd:C009413
Drug	gliquidone	AKR1C2 AKR1C3	9.43e-05	4	91	2	ctd:C010969
Drug	DBD-H	AKR1C4 AKR1C3	9.43e-05	4	91	2	CID000131382
Drug	Glycyrrhetinic Acid	AKR1C4 AKR1C2 AKR1C3	1.18e-04	24	91	3	ctd:D006034
Drug	Gallamine triethiodide [65-29-2]; Down 200; 4.4uM; MCF7; HT_HG-U133A	STAM2 ARFGEF1 FAAP100 UBTF AKR1C3 ZMYM3	1.26e-04	193	91	6	6215_DN
Drug	Delcorine; Down 200; 8.4uM; PC3; HT_HG-U133A	MAOA SPTBN2 SEMA5A ATP9B ATP2C2 TNS1	1.29e-04	194	91	6	4275_DN
Drug	Hemicholinium bromide [312-45-8]; Up 200; 7uM; PC3; HT_HG-U133A	ZFP30 PHTF2 ATP9B ADAM12 DCUN1D4 CLCN4	1.29e-04	194	91	6	6739_UP
Drug	prochlorperazine dimaleate salt; Down 200; 10uM; MCF7; HT_HG-U133A_EA	BRIP1 PHTF2 ARFGEF1 UBTF ZMYM3 NOTCH3	1.33e-04	195	91	6	1053_DN
Drug	9,10-phenanthrenequinone	AKR1C4 AKR1C2 AKR1C3	1.33e-04	25	91	3	ctd:C005399
Drug	Pregnanolone	AKR1C4 AKR1C2 AKR1C3	1.33e-04	25	91	3	ctd:D011280
Drug	sodium 4-phenylbutyrate; Up 200; 1000uM; HL60; HG-U133A	BRIP1 ATG13 ZFP30 DCUN1D4 CLCN3 DNMT3B	1.37e-04	196	91	6	411_UP
Drug	Carisoprodol [78-44-4]; Down 200; 15.4uM; PC3; HT_HG-U133A	ZFP30 PFKFB2 ANKRD6 ZNF467 FAAP100 CLCN4	1.37e-04	196	91	6	6610_DN
Drug	Etilefrine hydrochloride [534-87-2]; Up 200; 18.4uM; MCF7; HT_HG-U133A	SPTBN2 PFKFB2 ADAM12 TRIP11 CLCN4 TNS1	1.37e-04	196	91	6	4415_UP
Drug	Epirizole [18694-40-1]; Down 200; 17uM; PC3; HT_HG-U133A	MAOA ATG13 ARFGEF2 FAAP100 ATP2C2 ZNF85	1.41e-04	197	91	6	1803_DN
Drug	sulindac; Down 200; 50uM; MCF7; HG-U133A	BRIP1 MAOA SPTBN5 CLCN3 RNF141 TNS1	1.45e-04	198	91	6	307_DN
Drug	Etoposide [33419-42-0]; Down 200; 6.8uM; PC3; HT_HG-U133A	AMT ZFP30 SPTBN2 ZNF467 ADAM12 TNS1	1.45e-04	198	91	6	6681_DN
Drug	Naringin hydrate [11032-30-7]; Down 200; 6.6uM; HL60; HT_HG-U133A	STAM2 BRIP1 PHTF2 ARFGEF1 DCUN1D4 ZW10	1.45e-04	198	91	6	2425_DN
Drug	Heptaminol hydrochloride [543-15-7]; Up 200; 22uM; HL60; HT_HG-U133A	STAM2 UPB1 ARFGEF2 ATP9B DCUN1D4 CLCN4	1.45e-04	198	91	6	1866_UP
Drug	LY-171,883; Up 200; 1uM; MCF7; HG-U133A	STAM2 MAOA PFKFB2 ADAM12 AKR1C3 PAK1IP1	1.49e-04	199	91	6	222_UP
Drug	Dibucaine [85-79-0]; Down 200; 11.6uM; PC3; HG-U133A	STAM2 MAOA ATP9B UBTF EIF2AK2 ZMYM3	1.49e-04	199	91	6	1889_DN
Drug	Bephenium hydroxynaphthoate [3818-50-6]; Down 200; 9uM; PC3; HT_HG-U133A	AMT SPTBN2 SEMA5A FAAP100 CLCN4 NOTCH3	1.49e-04	199	91	6	4668_DN
Drug	Carbamazepine [298-46-4]; Up 200; 17uM; HL60; HT_HG-U133A	AMT MAOA PHTF2 CILK1 TRIP11 CLCN3	1.49e-04	199	91	6	1847_UP
Drug	0317956-0000 [391210-11-0]; Up 200; 1uM; PC3; HT_HG-U133A	SPTBN2 SEMA5A ATP9B SPTBN5 CLCN4 MUSK	1.49e-04	199	91	6	3777_UP
Drug	glycolithocholic acid	AKR1C4 AKR1C2 AKR1C3	1.50e-04	26	91	3	CID000115245
Drug	chlordecone	AKR1C4 AKR1C2 ATP2C2 AKR1C3	1.51e-04	67	91	4	CID000000299
Drug	LY294002; Up 200; 10uM; HL60; HG-U133A	MAOA ATG13 TRIP11 RNF141 NOTCH3 DNMT3B	1.53e-04	200	91	6	361_UP
Drug	NSC86000	AKR1C2 AKR1C3	1.57e-04	5	91	2	CID000257630
Drug	estriol succinate	ABCD1 PLG	1.57e-04	5	91	2	CID000010577
Drug	farnesal	AKR1C2 AKR1C3	1.57e-04	5	91	2	ctd:C084519
Drug	5 beta-pregnane-3,20-dione	AKR1D1 AKR1C4 AKR1C2 AKR1C3	2.00e-04	72	91	4	CID000092745
Drug	AC1L93E5	AKR1C4 AKR1C3	2.35e-04	6	91	2	CID000412383
Drug	AC1L99R1	AKR1D1 AKR1C4	2.35e-04	6	91	2	CID000440680
Drug	Estazolam	AKR1C2 AKR1C3	2.35e-04	6	91	2	ctd:D004949
Drug	Glipizide	AKR1C2 AKR1C3	2.35e-04	6	91	2	ctd:D005913
Drug	acenaphthene-1-ol	AKR1C2 AKR1C3	2.35e-04	6	91	2	ctd:C023723
Drug	Dalacin T	TBC1D1 TDP1	2.35e-04	6	91	2	CID000032603
Drug	benzo(a)pyrene 7,8-dihydrodiol	AKR1C4 AKR1C2 AKR1C3	2.56e-04	31	91	3	ctd:C017228
Drug	ochratoxin A	STAM2 UPB1 BRIP1 MAOA DCUN1D5 DPY19L1 WDR46 ARFGEF1 AKR1C2 TBC1D1 AKR1C3 ZMYM3	2.70e-04	911	91	12	ctd:C025589
Drug	Budesonide	AKR1D1 AKR1C4 AKR1C2 AKR1C3	2.99e-04	80	91	4	ctd:D019819
Drug	(7R,12S)-17-(1,5-dimethylhexyl)-7,12-dihydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one	AKR1D1 AKR1C4	3.27e-04	7	91	2	CID000440682
Drug	4-hydroxyequilenin-o-quinone	AKR1C2 AKR1C3	3.27e-04	7	91	2	ctd:C117714
Drug	zomepirac	AKR1C2 AKR1C3	3.27e-04	7	91	2	ctd:C020549
Disease	MALE PSEUDOHERMAPHRODITISM: DEFICIENCY OF TESTICULAR 17,20-DESMOLASE	AKR1C4 AKR1C2	8.79e-06	2	88	2	C1839840
Disease	46,XY disorder of sex development due to testicular 17,20-desmolase deficiency	AKR1C4 AKR1C2	8.79e-06	2	88	2	cv:C1839840
Disease	46,XY sex reversal 8 (is_implicated_in)	AKR1C4 AKR1C2	8.79e-06	2	88	2	DOID:0111773 (is_implicated_in)
Disease	46,XY SEX REVERSAL 8	AKR1C4 AKR1C2	8.79e-06	2	88	2	614279
Disease	Neoplasms, Hormone-Dependent	AKR1C2 AKR1C3	2.63e-05	3	88	2	C0027661
Disease	Dent disease (implicated_via_orthology)	CLCN3 CLCN4	2.63e-05	3	88	2	DOID:0050699 (implicated_via_orthology)
Disease	susceptibility to hepatitis B infection measurement	UPB1 ARFGEF2 WDR17 PREX1	4.09e-05	64	88	4	EFO_0008405
Disease	unipolar depression, depressive symptom measurement	ARFGEF2 ZKSCAN2 PREX1	6.34e-05	26	88	3	EFO_0003761, EFO_0007006
Disease	Hermaphroditism	AKR1C2 AKR1C3	8.74e-05	5	88	2	C0019269
Disease	Ambiguous Genitalia	AKR1C2 AKR1C3	8.74e-05	5	88	2	C0266362
Disease	Pseudohermaphroditism	AKR1C2 AKR1C3	8.74e-05	5	88	2	C0033804
Disease	chronic kidney disease, APOL1 risk genotype carrier status	OTOGL PLG	8.74e-05	5	88	2	EFO_0003884, EFO_0009324
Disease	Intersex Conditions	AKR1C2 AKR1C3	8.74e-05	5	88	2	C2930618
Disease	Sex Differentiation Disorders	AKR1C2 AKR1C3	8.74e-05	5	88	2	C2930619
Disease	cortolone glucuronide (1) measurement	AKR1C2 AKR1C3	1.31e-04	6	88	2	EFO_0800552
Disease	Disorders of Sex Development	AKR1C2 AKR1C3	1.83e-04	7	88	2	C0036875
Disease	osteopetrosis (implicated_via_orthology)	CLCN3 CLCN4	1.83e-04	7	88	2	DOID:13533 (implicated_via_orthology)
Disease	Abruptio Placentae	DOCK2 ADAM12	5.69e-04	12	88	2	EFO_1001754
Disease	temporal arteritis	PLG PHTF1	5.69e-04	12	88	2	EFO_1001209
Disease	polyp of colon	PREX1 TTLL13 TNS3	6.34e-04	56	88	3	MONDO_0021400
Disease	Kartagener syndrome (implicated_via_orthology)	DAW1 DNAH5	7.82e-04	14	88	2	DOID:0050144 (implicated_via_orthology)
Disease	infant head circumference	ARFGEF2 PREX1	9.00e-04	15	88	2	EFO_0004577
Disease	primary ciliary dyskinesia (implicated_via_orthology)	DAW1 DNAH5	1.45e-03	19	88	2	DOID:9562 (implicated_via_orthology)
Disease	lysophosphatidylcholine 20:5 measurement	AKR1D1 MUSK	1.45e-03	19	88	2	EFO_0010364
Disease	longevity	ARFGEF2 TSTD3 AKR1C3 SUZ12 PREX1	1.63e-03	284	88	5	EFO_0004300
Disease	response to selective serotonin reuptake inhibitor	ARFGEF2 TBC1D1 PREX1	1.91e-03	82	88	3	EFO_0005658
Disease	aggressive behavior	ARFGEF2 TBX20	2.52e-03	25	88	2	EFO_0003015
Disease	blood rubidium measurement	ARFGEF2 PREX1	2.73e-03	26	88	2	EFO_0021529
Disease	Parkinson disease	BRIP1 SEMA5A CLCN3 RNF141 UBTF	2.77e-03	321	88	5	MONDO_0005180
Disease	coronary artery disease	NBEAL1 ARFGEF2 SEMA5A ANKRD6 VWDE PLG TBX20 TNS1 PREX1 TNS3	2.93e-03	1194	88	10	EFO_0001645

Protein segments in the cluster

Peptide	Gene	Start	Entry
TVDLSATWEVMEKCK	AKR1C4	141	P17516
ATWEVMEKCKDAGLA	AKR1C4	146	P17516
WKILNEIDAGVCEEM	PFKFB2	321	O60825
WLKGMTSLQCDTTEK	DCUN1D4	161	Q92564
LKTSEGDSMELEIWC	ATG13	86	O75143
VVMNGKEDVLWCTEL	DNMT3B	791	Q9UBC3
EILECQVMWEPDSKK	AACS	11	Q86V21
IVDLCTTWEAMEKCK	AKR1C3	141	P42330
TTWEAMEKCKDAGLA	AKR1C3	146	P42330
WEAMEACKDAGLVKS	AKR1D1	151	P51857
LVSILKCMVEWSKDQ	ARFGEF1	616	Q9Y6D6
CLVSILKCMVEWSKD	ARFGEF2	566	Q9Y6D5
LVGVEVWNDMDKCSV	ADAM12	261	O43184
AVDWMTDLKEGVCLS	CLCN4	91	P51793
LMKDTCNTGKWTEEE	DMTF1	266	Q9Y222
WLKGMTSLQCDCTEK	DCUN1D5	106	Q9BTE7
WMAVKCSLKTEDQED	ATP2C2	491	O75185
ISLVDELKTWCMLKI	ANKRD6	496	Q9Y2G4
VMCKGLEKSDDDTWI	NBEAL1	1451	Q6ZS30
ELMALKWCDGKEVTM	PGBD4	381	Q96DM1
EAMCDWKDVLSGGEK	ABCD1	596	P33897
CLNTEWVEMKSKALL	CFAP95	101	Q5VTT2
TMKELIDKICWTKTA	MAOA	156	P21397
MITVVLEEAKEKWDC	LTV1	336	Q96GA3
KIWMLTGDKLETATC	ATP9B	761	O43861
LMTCAKEDSVKLWGS	HERC1	3641	Q15751
WMDTECPEAKRLKVE	NOTCH3	1721	Q9UM47
ILTGSMDKTCKLWDA	DAW1	276	Q8N136
TKIMDLIGIQTKICW	DPY19L1	121	Q2PZI1
CWIVCTTLKLQMEKG	NLRP2	401	Q9NX02
MLAIKASWDESGKLV	FAAP100	321	Q0VG06
MCKAWDIEELVSLGK	BRIP1	331	Q9BX63
GKMWEEAISLCKELA	DOCK2	1291	Q92608
WKCDMQKLTVDELKR	CABP7	121	Q86V35
MEFCDKGTLEQWIEK	EIF2AK2	366	P19525
MAGAEWKSLEECLEK	UPB1	1	Q9UBR1
IVLEKDAMDVWCNGK	FAIM	111	Q9NVQ4
DAMDVWCNGKKLETA	FAIM	116	Q9NVQ4
SWDECMNLREVKSLK	MAK	41	P20794
AGCWEKDLALMQDKV	AMT	146	P48728
EKADMVDGIKESVCW	NEURL4	1311	Q96JN8
ELEWVTKEKGATLLC	NEURL4	1541	Q96JN8
NPETLGKIEDCMKVW	DNAH5	246	Q8TE73
GKIEDCMKVWIKQTE	DNAH5	251	Q8TE73
EAEVVMGIIDKWTCC	OTOGL	1916	Q3ZCN5
CSKVSGKVDWKMLDE	NAV1	1446	Q8NEY1
VWEGNDCKKADMSVL	PHTF2	466	Q8N3S3
VCMAKTAEEKQKWLD	PREX1	371	Q8TCU6
EETWVAETLCGLKMK	SPDYE10	81	P0DUX0
EETWVAETLCGLKMK	SPDYE11	81	P0DTA3
EETWVAETLCGLKMK	SPDYE8	81	P0DUD1
LSKAECTKIWTEKIM	SH3GLB1	46	Q9Y371
CWIVCTTLKLQMEKG	NLRP7	366	Q8WX94
CELMVELGEWDKALS	WDR17	836	Q8IZU2
LDKMCTICKAQESWL	TNS3	81	Q68CZ2
KISKTMSGLECQAWD	PLG	196	P00747
TVFDDCKKEGEWKIM	STXBP3	21	O00186
CKKEGEWKIMLLDEF	STXBP3	26	O00186
EETWVVEMLCGLKMK	SPDYE2B	91	A6NHP3
EKMERWLCSKEDSLA	SPTBN5	2586	Q9NRC6
WDVVMKKCTSLEESL	SEMA5A	506	Q13591
ATWEAMEKCKDAGLA	AKR1C2	146	P52895
SWEECMNLREVKSLK	CILK1	41	Q9UPZ9
DWMTDLKEGICLSAL	CLCN3	151	P51790
EMCVKDVLLKDDLSW	VWDE	836	Q8N2E2
WLCSEFKESMLTLGK	TDP1	411	Q9NUW8
CTDGMIKWVKVSTQD	SIRPB2	66	Q5JXA9
SQWKVMERIKSCGLE	ZFP30	101	Q9Y2G7
VVCVWEMGTSKEKAK	WDFY3	3101	Q8IZQ1
DCHELKLWIDEKMLT	SPTBN2	1286	O15020
AIIWEGNECKKMDMS	PHTF1	441	Q9UMS5
LWMGRVKQLTDEEEC	RNF141	141	Q8WVD5
EETWVAETLCGLKMK	SPDYE12	81	P0DUX1
EETWVAETLCGLKMK	SPDYE13	81	A0A494C0Z2
EETWVAETLCGLKMK	SPDYE14	81	P0DUD3
EETWVAETLCGLKMK	SPDYE15	81	P0DUD4
EETWVVEMLCGLKMK	SPDYE16	51	A6NNV3
EETWVAETLCGLKMK	SPDYE17	81	P0DUD2
EETWVVEMLCGLKMK	SPDYE18	91	P0DV79
EETWVVETLCGLKMK	SPDYE21	91	A0A494C086
EETWVVEMLCGLKMK	SPDYE2	91	Q495Y8
EETWVAETLCGLKMK	SPDYE3	146	A6NKU9
TWVAETLCGLKMKAK	SPDYE3	221	A6NKU9
ETWVAETLCGLKMKA	SPDYE3	366	A6NKU9
EETWVVEMLCGLKMK	SPDYE5	91	A6NIY4
EETWVVEMLCGLKMK	SPDYE6	91	P0CI01
EMEECPISKKRATWE	SUZ12	321	Q15022
KTLADMKVTLKELCW	SOGA1	741	O94964
EETWVVETLCGLKMK	SPDYE1	51	Q8NFV5
ALEKICSICKAMDTW	TNS1	86	Q9HBL0
CLKEVTTVWEKMLST	TBC1D1	766	Q86TI0
CEKLKSLMVEWSEEF	STAM2	106	O75886
VDCKWLTVSEVMKLL	RHPN2P1	461	A8MT19
LTCLGVWLDKVADMK	PAK1IP1	296	Q9NWT1
ALDWVTKKLMCEINV	WDR46	221	O15213
KICDAISKWEQAMKE	PLEKHH1	1061	Q9ULM0
MVKVWDCNTGKCLET	WDR38	256	Q5JTN6
MEKGEIEAELCWAKK	TRIP11	716	Q15643
EGCLIMKVEKDPEWA	ZKSCAN2	16	Q63HK3
DLITCLEQGKEAWSM	ZNF85	51	Q03923
EETWVVEMLCGLKMK	nan	51	A6NJR5
EETWVAETLCGLKMK	SPDYE9	81	A0A494C191
MKIEKCGWSEGLTSI	TSTD3	1	H0UI37
EMAKIACSLETKELW	TBX20	96	Q9UMR3
DMCKLKWVEISNEVR	UBTF	66	P17480
AVVMKNWKEIVESCD	SEC31A	631	O94979
CKVEMKSKGSQTEEW	ZMYM3	846	Q14202
CPGEEWMIRKVKVED	ZNF467	86	Q7Z7K2
RMSCSWPGKDEKEVE	TRIM59	311	Q8IWR1
GDMIWEDLSECLIKN	ZW10	331	O43264
MCGLKEVGEDEEWTL	TTLL13	106	A6NNM8
VKELFCAKEWLVMEE	MUSK	401	O15146