Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprostaglandin transmembrane transporter activity

SLCO1B7 SLCO1B3

4.13e-0514142GO:0015132
GeneOntologyMolecularFunctionicosanoid transmembrane transporter activity

SLCO1B7 SLCO1B3

4.77e-0515142GO:0071714
GeneOntologyMolecularFunctionoligopeptide transmembrane transporter activity

SLCO1B7 SLCO1B3

5.45e-0516142GO:0035673
GeneOntologyMolecularFunctionsodium-independent organic anion transmembrane transporter activity

SLCO1B7 SLCO1B3

6.94e-0518142GO:0015347
GeneOntologyMolecularFunctionbile acid transmembrane transporter activity

SLCO1B7 SLCO1B3

2.53e-0434142GO:0015125
GeneOntologyMolecularFunctionamide transmembrane transporter activity

SLCO1B7 SLCO1B3

3.87e-0442142GO:0042887
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLCO1B7 TMEM63C SLCO1B3 CACNA1F SEC61G

9.13e-041180145GO:0022857
GeneOntologyMolecularFunctionorganic hydroxy compound transmembrane transporter activity

SLCO1B7 SLCO1B3

1.07e-0370142GO:1901618
GeneOntologyMolecularFunctionlipid transmembrane transporter activity

SLCO1B7 SLCO1B3

1.17e-0373142GO:0170055
GeneOntologyMolecularFunctiontransporter activity

SLCO1B7 TMEM63C SLCO1B3 CACNA1F SEC61G

1.36e-031289145GO:0005215
GeneOntologyMolecularFunctionmonocarboxylic acid transmembrane transporter activity

SLCO1B7 SLCO1B3

1.76e-0390142GO:0008028
GeneOntologyMolecularFunctionserine-type endopeptidase inhibitor activity

SLCO1B7 SLCO1B3

2.39e-03105142GO:0004867
GeneOntologyMolecularFunctionribosome binding

DHX29 SEC61G

3.11e-03120142GO:0043022
GeneOntologyMolecularFunctionendopeptidase inhibitor activity

SLCO1B7 SLCO1B3

6.85e-03180142GO:0004866
GeneOntologyMolecularFunctionpeptidase inhibitor activity

SLCO1B7 SLCO1B3

7.37e-03187142GO:0030414
GeneOntologyMolecularFunctionlipid transporter activity

SLCO1B7 SLCO1B3

8.07e-03196142GO:0005319
GeneOntologyMolecularFunctionendopeptidase regulator activity

SLCO1B7 SLCO1B3

8.47e-03201142GO:0061135
GeneOntologyMolecularFunctionribonucleoprotein complex binding

DHX29 SEC61G

8.88e-03206142GO:0043021
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLCO1B7 SLCO1B3

8.97e-03207142GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLCO1B7 SLCO1B3

9.05e-03208142GO:0005342
GeneOntologyBiologicalProcesssodium-independent organic anion transport

SLCO1B7 SLCO1B3

5.15e-0515152GO:0043252
GeneOntologyBiologicalProcessoligopeptide transport

SLCO1B7 SLCO1B3

1.24e-0423152GO:0006857
GeneOntologyCellularComponentendoplasmic reticulum protein-containing complex

SEC61G SYVN1

4.03e-03125162GO:0140534
GeneOntologyCellularComponentmembrane protein complex

CDH19 CACNA1F SEC61G C7 SYVN1

4.20e-031498165GO:0098796
DomainXK-related

XKRX XKR3

3.77e-0511162PF09815
DomainXK_rel

XKRX XKR3

3.77e-0511162IPR018629
DomainOA_transporter

SLCO1B7 SLCO1B3

4.52e-0512162IPR004156
DomainOATP

SLCO1B7 SLCO1B3

4.52e-0512162PF03137
DomainMFS_dom

SLCO1B7 SLCO1B3 MFSD11

1.89e-04134163IPR020846
DomainKazal_2

SLCO1B7 SLCO1B3

4.26e-0436162PF07648
DomainKAZAL_2

SLCO1B7 SLCO1B3

8.23e-0450162PS51465
DomainKazal_dom

SLCO1B7 SLCO1B3

8.56e-0451162IPR002350
DomainMFS

SLCO1B7 SLCO1B3

3.77e-03108162PS50850
PathwayREACTOME_TRANSPORT_OF_ORGANIC_ANIONS

SLCO1B7 SLCO1B3

3.64e-0512112MM15476
PathwayREACTOME_ATORVASTATIN_ADME

SLCO1B7 SLCO1B3

5.78e-0515112MM15697
PathwayREACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS

SLCO1B7 SLCO1B3

9.40e-0519112MM14612
PathwayREACTOME_HEME_DEGRADATION

SLCO1B7 SLCO1B3

1.04e-0420112MM14721
PathwayREACTOME_METABOLISM_OF_PORPHYRINS

SLCO1B7 SLCO1B3

2.71e-0432112MM14719
PathwayREACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES

SLCO1B7 SLCO1B3

4.46e-0441112MM15075
PathwayREACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM

SLCO1B7 SLCO1B3

5.38e-0445112MM14751
PathwayKEGG_VIBRIO_CHOLERAE_INFECTION

ADCY3 SEC61G

7.75e-0454112M17906
Pubmed

Identification of two new members, XPLAC and XTES, of the XK family.

XKRX XKR3

1.98e-07216216431037
Pubmed

Interaction Between Sex and Organic Anion-Transporting Polypeptide 1b2 on the Pharmacokinetics of Regorafenib and Its Metabolites Regorafenib-N-Oxide and Regorafenib-Glucuronide in Mice.

SLCO1B7 SLCO1B3

5.95e-07316230955241
Pubmed

Influence of drug formulation on OATP1B-mediated transport of paclitaxel.

SLCO1B7 SLCO1B3

5.95e-07316224755470
Pubmed

Identification, expression, and functional characterization of full-length and splice variants of murine organic anion transporting polypeptide 1b2.

SLCO1B7 SLCO1B3

5.95e-07316219400585
Pubmed

Synergistic interaction between genetics and disease on pravastatin disposition.

SLCO1B7 SLCO1B3

5.95e-07316224613363
Pubmed

Organic anion transporting polypeptide 1B transporters modulate hydroxyurea pharmacokinetics.

SLCO1B7 SLCO1B3

5.95e-07316223986199
Pubmed

Targeted disruption of murine organic anion-transporting polypeptide 1b2 (Oatp1b2/Slco1b2) significantly alters disposition of prototypical drug substrates pravastatin and rifampin.

SLCO1B7 SLCO1B3

5.95e-07316218413659
Pubmed

Full-length cDNA cloning and genomic organization of the mouse liver-specific organic anion transporter-1 (lst-1).

SLCO1B7 SLCO1B3

5.95e-07316210833452
Pubmed

OATP1B2 deficiency protects against paclitaxel-induced neurotoxicity.

SLCO1B7 SLCO1B3

5.95e-07316229337310
Pubmed

Expression of Oatp2 in the Brain and Liver of Alzheimer Disease Mouse Model.

SLCO1B7 SLCO1B3

5.95e-07316231967785
Pubmed

Characterization of organic anion transporting polypeptide 1b2-null mice: essential role in hepatic uptake/toxicity of phalloidin and microcystin-LR.

SLCO1B7 SLCO1B3

5.95e-07316218296417
Pubmed

Role of the murine organic anion-transporting polypeptide 1b2 (Oatp1b2) in drug disposition and hepatotoxicity.

SLCO1B7 SLCO1B3

5.95e-07316218492796
Pubmed

Organic anion-transporting polypeptide 1b2 (Oatp1b2) is important for the hepatic uptake of unconjugated bile acids: Studies in Oatp1b2-null mice.

SLCO1B7 SLCO1B3

5.95e-07316220949553
Pubmed

Differential Expression of OATP1B3 Mediates Unconjugated Testosterone Influx.

SLCO1B7 SLCO1B3

5.95e-07316228389619
Pubmed

Impact of Oatp1c1 deficiency on thyroid hormone metabolism and action in the mouse brain.

SLCO1B7 SLCO1B3

1.19e-06416222294745
Pubmed

Protection against phalloidin-induced liver injury by oleanolic acid involves Nrf2 activation and suppression of Oatp1b2.

SLCO1B7 SLCO1B3

1.19e-06416225280775
Pubmed

Contribution of Organic Anion-Transporting Polypeptides 1A/1B to Doxorubicin Uptake and Clearance.

SLCO1B7 SLCO1B3

1.19e-06416227777271
Pubmed

Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs.

SLCO1B7 SLCO1B3

1.19e-06416220644253
Pubmed

OATP1A/1B transporters affect irinotecan and SN-38 pharmacokinetics and carboxylesterase expression in knockout and humanized transgenic mice.

SLCO1B7 SLCO1B3

1.98e-06516224194565
Pubmed

Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver.

SLCO1B7 SLCO1B3

2.97e-06616222232210
Pubmed

Analysis of DNA methylation and histone modification profiles of liver-specific transporters.

SLCO1B7 SLCO1B3

2.97e-06616219047482
Pubmed

Critical role of PPAR-alpha in perfluorooctanoic acid- and perfluorodecanoic acid-induced downregulation of Oatp uptake transporters in mouse livers.

SLCO1B7 SLCO1B3

8.91e-061016218703564
Pubmed

The Diet1 locus confers protection against hypercholesterolemia through enhanced bile acid metabolism.

SLCO1B7 SLCO1B3

1.54e-051316211682476
Pubmed

Changes in thyroid status during perinatal development of MCT8-deficient male mice.

SLCO1B7 SLCO1B3

3.02e-051816223696569
Pubmed

Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: general implications for tissue fusion processes.

FZD6 ADCY3

7.45e-052816220940229
Pubmed

Mitochondrial phosphoproteome revealed by an improved IMAC method and MS/MS/MS.

SLCO1B7 SLCO1B3

3.12e-045716217208939
CytobandEnsembl 112 genes in cytogenetic band chr12p12

SLCO1B7 SLCO1B3

7.05e-04113162chr12p12
GeneFamilyBlood group antigens|XK related family

XKRX XKR3

2.21e-0511122955
GeneFamilySolute carriers

SLCO1B7 SLCO1B3

2.72e-02395122752
ToppCellTracheal-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CDH19 ADCY3 SEC61G

4.44e-0519716306e17c9ad53463eee1007280b3f3e8b0cf446cdc
ToppCellSubstantia_nigra-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

TMEM63C XKRX

5.41e-0497162d93193cc8455373467a9e63d8b883c3139773a03
ToppCellSubstantia_nigra-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

TMEM63C XKRX

5.41e-04971621dc648eb31b41419fbd859e9fab4a32ed4226a97
ToppCellLPS_only-Unknown|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CDH19 ADCY3

7.59e-041151627a733f6987b40ec497a03734b79ed5355ad3a2fc
ToppCellLPS_only-Unknown-Endothelial-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CDH19 ADCY3

7.59e-04115162c67145d3cd9243994a141749b426ff2a6dcc8d93
ToppCellLPS_only-Unknown-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CDH19 ADCY3

7.59e-04115162ad5298c2ad8bf94fa13c2e50b0799e929473ef59
ToppCellLPS-IL1RA+antiTNF-Unknown-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FZD6 ADCY3

9.98e-0413216246c80eab16a70da9f363a9fbdf50bccab0b287d7
ToppCellLPS-IL1RA+antiTNF-Unknown|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FZD6 ADCY3

9.98e-04132162a022c3c41654166cb106f27dc54fa88e8c40f898
ToppCellRV-14._Fibroblast_III|World / Chamber and Cluster_Paper

CDH19 C7

1.03e-031341628c4046ba1f85172915a112499e492c3efe8474c2
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FZD6 C7

1.04e-031351620e5dfbe79598fc7822a7b3baa8d7dba3c9da1dad
ToppCellRV-14._Fibroblast_III|RV / Chamber and Cluster_Paper

CDH19 C7

1.12e-03140162b4fee8eb6bf855b364b00bda3f78e49d851bbca0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY3 C7

1.19e-03144162cf9f049ab6cd80521598124f057c2debdde24788
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY3 C7

1.19e-0314416241eaeca54b3c39de417597267cbdb1f195dd885a
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

XKRX SLCO1B3

1.25e-0314816231a7c2b20970070b14d2b955020320a6f99db547
ToppCell368C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|368C / Donor, Lineage, Cell class and subclass (all cells)

CDH19 C7

1.32e-03152162ee7855d76a49d07a032677a4dc83aa6116d50518
ToppCell368C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|368C / Donor, Lineage, Cell class and subclass (all cells)

CDH19 C7

1.32e-031521623a1414ba6a4972698c3262a00b124428835c35cb
ToppCell343B-Epithelial_cells-Epithelial-E_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CACNA1F C7

1.34e-0315316232cf4ca828d228f23366480305592f9813fed7ff
ToppCell343B-Epithelial_cells-Epithelial-E_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CACNA1F C7

1.34e-03153162d5f5399ebbbff508c96ce7f01272716b61597ab5
ToppCellCV-Healthy-3|Healthy / Virus stimulation, Condition and Cluster

CACNA1F ADCY3

1.35e-0315416226bf81a86700db7e65c2384ffe94ed4253ea4047
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CDH19 ADCY3

1.39e-031561626365b69ede98bc866e996bc52736b00401aacf6f
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CDH19 ADCY3

1.41e-03157162bfec34182f052cf1c0d847ba53ea335d4d1190de
ToppCellsevere_COVID-19-pDC|World / disease group, cell group and cell class (v2)

FZD6 CACNA1F

1.44e-03159162e1c48c4ceda116826819ff9adeed7bad6a58844d
ToppCellsevere_COVID-19-pDC|severe_COVID-19 / disease group, cell group and cell class (v2)

FZD6 CACNA1F

1.44e-03159162ea5088d27e42b8850455764d53b757ea8d8f14bc
ToppCellCV-Healthy-3|CV / Virus stimulation, Condition and Cluster

CACNA1F ADCY3

1.48e-03161162fd4a79385ea967b9900dc76a3add813b894a3a28
ToppCell10x5'v1-week_17-19-Hematopoietic-HSC/MPP_and_pro-HSC/MPP|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TMEM63C CACNA1F

1.48e-03161162aee74a2e7a8acd2950341963f1c04b59c7862183
ToppCell10x3'2.3-week_17-19-Hematopoietic-HSC/MPP_and_pro-HSC/MPP|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FZD6 XKR3

1.50e-03162162e73c644ce1db34f1d390878954e86fa0b3a455a1
ToppCelldroplet-Lung-nan-18m-Lymphocytic-Zbtb32+_B|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM63C XKRX

1.57e-031661623e3e9296e6919a38602e417a6606c046af3bd101
ToppCellfacs-Liver-Hepatocytes-24m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1F ADCY3

1.61e-031681624ae9e9d93bcd6f4d5815e57fd5afa7a3398a0ec1
ToppCellfacs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1F ADCY3

1.61e-0316816204e168fe1d6f5f9e3d3bf9d7c13e800e3594868a
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMEM174 C7

1.61e-03168162d2b91f2adc95dcfa623f8d7ca2df1c6f884da988
ToppCellRA-01._Fibroblast_I|RA / Chamber and Cluster_Paper

CDH19 C7

1.63e-031691626373562ab3b1765060212a6a53d6543e7e942e80
ToppCellfacs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1F ADCY3

1.63e-03169162454b92b9b67299a64278c010db033ca5b9d217a0
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CDH19 ADCY3

1.64e-031701625570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellControl-Fibroblasts-Pericytes|Control / group, cell type (main and fine annotations)

CDH19 ADCY3

1.66e-03171162080003f698f867935c2bfc55d241d3650f45a0ab
ToppCell11.5-Airway-Epithelial-Basal_cell|Airway / Age, Tissue, Lineage and Cell class

FZD6 XKRX

1.68e-031721629d4d92e2d16dfc8a394f2641653bb97de20a2530
ToppCellmetastatic_Brain-Fibroblasts-Undetermined|Fibroblasts / Location, Cell class and cell subclass

FZD6 MFSD11

1.68e-03172162c3822ff7329c3ac38c68c5c38cd67c390682e2a6
ToppCellMild-CD4+_T_Exhausted|World / Disease group and Cell class

FZD6 XKRX

1.68e-03172162efe68d9477aa873b1637ee689f298120303aa322
ToppCellAdult-Mesenchymal-pericyte_cell-D175|Adult / Lineage, Cell type, age group and donor

CDH19 ADCY3

1.70e-03173162fd6653d6be9ca6ac36798590694efe03cb758c67
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-Plasma_cells-IgM_plasma_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEC61G SYVN1

1.70e-0317316277e2b2e66c89984769f2800bdeeab42f9cf9fc46
ToppCell343B-Fibroblasts-Fibroblast-H-|343B / Donor, Lineage, Cell class and subclass (all cells)

ADCY3 C7

1.72e-031741622627c3983009839fedbc5e3f628739dc026447f4
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CDH19 C7

1.72e-031741629c916af5eebd932f67dc9117e1d26ff194a2ff2c
ToppCell343B-Fibroblasts-Fibroblast-H|343B / Donor, Lineage, Cell class and subclass (all cells)

ADCY3 C7

1.72e-03174162507a33e58f62e2b72f0bcc743e84dbd0bf705a15
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CDH19 C7

1.72e-03174162bc71521f44a5fe013af42b06b5d1bd2446ecf3b5
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CDH19 SEC61G

1.74e-031751629a96a946db731ba24c9be34bedebf1f4a1372b9e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CDH19 SEC61G

1.74e-031751622b51406a2c2daa13ab4ed283ede038cd11d9e641
ToppCellMild-CD4+_T_Exhausted|Mild / Disease group and Cell class

FZD6 XKRX

1.74e-031751626df099f37875f2cd63502b732a2e07ebfec50e47
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CDH19 SEC61G

1.74e-0317516254c1f080195ad8392a095e83b56a4b54073d4c0d
ToppCell356C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|356C / Donor, Lineage, Cell class and subclass (all cells)

TMEM63C C7

1.76e-031761622287bd8382f41e36ebb0875a0133bada1ec81fa7
ToppCell356C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|356C / Donor, Lineage, Cell class and subclass (all cells)

TMEM63C C7

1.76e-03176162135d51d28a7ad2a67d5a6c49eb6e661f4beb66f5
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDH19 ADCY3

1.78e-03177162452ec2df36c6d656a7cdadc55be545ccdb146a29
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY3 C7

1.80e-0317816278a0c6340001a77f5b2d890b6263f574af2e72da
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY3 C7

1.80e-03178162d4ecb84e9b1f4ec49c519321156aa10f9bd34cce
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_4|343B / Donor, Lineage, Cell class and subclass (all cells)

XKRX ADCY3

1.82e-03179162c09c3eed43d1aa3b7aa8f3021e6f2737840cde16
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDH19 ADCY3

1.82e-03179162dc6cd46fa652b296ddbc41855f6377946d0a4cdc
ToppCellLA-01._Fibroblast_I|LA / Chamber and Cluster_Paper

CDH19 C7

1.82e-03179162dcb6ec9ae72b13fe388b72dace2815293fafe8ee
ToppCellfacs-Marrow-B-cells-18m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XKRX SEC61G

1.86e-03181162e6c78038b14100e0c9c6fe25e8f0b75c02c33549
ToppCellRA-01._Fibroblast_I|World / Chamber and Cluster_Paper

CDH19 C7

1.86e-031811622b6ddeb53a79a658e2ba78527ff48c155b20daa6
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CDH19 ADCY3

1.86e-03181162451b87ac95154bb80018b8dd245b4a6389d81411
ToppCellfacs-Marrow-B-cells-18m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XKRX SEC61G

1.86e-03181162e2481291c236105774c53883e6f20da11941df9b
ToppCellfacs-Marrow-B-cells-18m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XKRX SEC61G

1.86e-03181162782716b8b1d447d2bbe09a693fa5ed7ebeac0efb
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

CDH19 C7

1.88e-03182162fbd5e332df73bf7141c822fa67b76367dc962017
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CDH19 ADCY3

1.90e-031831628a799807fbf24456a9811e0c64068187940a2f71
ToppCellAdult-Mesenchymal-pericyte_cell-D122|Adult / Lineage, Cell type, age group and donor

CDH19 ADCY3

1.90e-03183162fc31a43a637423cb3bb9aa184a3a889a0b9aaea6
ToppCellILEUM-inflamed-(5)_IgA_plasma_cells|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SEC61G SYVN1

1.90e-03183162a113558ca4220bac31f9336033dff82a618d9258
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CDH19 ADCY3

1.92e-03184162102b6f621a5b551e622f97b12d787c080b052a72
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CDH19 ADCY3

1.92e-03184162689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CDH19 ADCY3

1.92e-03184162327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCellCOVID-19-Fibroblasts-Pericytes|COVID-19 / group, cell type (main and fine annotations)

CDH19 ADCY3

1.94e-031851624905adaeeffd353e089578e5ea614437dbe794e6
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

CDH19 C7

1.94e-031851628f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FZD6 CACNA1F

1.94e-03185162602536a3308a848f106adcb0a83530997440c8f4
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

XKRX ADCY3

1.96e-03186162bca5215d406f1785bf3a420201d5686071fcaca5
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-C|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

XKRX SEC61G

1.96e-03186162c30fd15f6b4b6edfbdf18a019aaad7fed3cf91fe
ToppCellILEUM-inflamed-(5)_Plasma|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SEC61G SYVN1

1.96e-031861624d105437487bf04f8cd6129b822d5c060af0bee8
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDH19 ADCY3

1.96e-03186162888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY3 C7

1.98e-03187162ac8e092b37e042975e2ee057d3f7c6821e58e8b5
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY3 C7

1.98e-03187162d591a3c216997663ab77710fed0d230ffc37e41a
ToppCellAdult-Mesenchymal-pericyte_cell|Adult / Lineage, Cell type, age group and donor

CDH19 ADCY3

1.98e-0318716262759efb660179402fb574ce5701c89a2e17bcfe
ToppCellCOPD-Stromal-Pericyte|Stromal / Disease state, Lineage and Cell class

CDH19 ADCY3

1.98e-03187162406ecd1dabb3ed8d871aef159f7bd1e383434953
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CDH19 ADCY3

1.98e-03187162958402fcc78f4c7a7d13d659d776f3817137975f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CDH19 ADCY3

1.98e-0318716248bfdb3504c3fefe5db3abac4b790c369680ab4e
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY3 C7

1.98e-03187162d1dc8c9a2c2cd10c640257161a75e7730ec5bb41
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CDH19 ADCY3

1.98e-0318716286250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CDH19 ADCY3

2.01e-03188162ee151792c7ac9afe820f1a281c6dab383799f358
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CDH19 C7

2.01e-03188162c32d023a69b6da79687ff8fa7485e7499db57046
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CDH19 ADCY3

2.01e-03188162ccddc08121caff958a2b6f9e278a018858af6b4d
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CDH19 C7

2.01e-031881621cd5a4d744bd3777246958ea5eb94388a5cbad81
ToppCell10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma-muscle_stem_cell|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CDH19 C7

2.01e-03188162de6f4889e0c5f39fbbaefd85526f645c6afa09d5
ToppCellCOVID-19-Heart-Fib_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

CDH19 C7

2.01e-03188162fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCell5'-Adult-SmallIntestine-Epithelial-goblet-Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1F SEC61G

2.01e-0318816291fa9cc29cbc88d3c29590ecee5c8ce858ac0aa7
ToppCell5'-Adult-SmallIntestine-Epithelial-goblet|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1F SEC61G

2.03e-031891626f4f2911fcbf3b43718b6183dbd9c970d4c19607
ToppCellMesenchymal-pericyte_cell|World / Lineage, Cell type, age group and donor

CDH19 ADCY3

2.03e-03189162d7ed96add29f219183c802895fbff519b627f635
ToppCellB_cells-Plasmablasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

SEC61G SYVN1

2.03e-0318916287cb7b6ba9fd57100d68e6eaeecd1ac6ab22d1c6
ToppCellRA-14._Fibroblast_III|RA / Chamber and Cluster_Paper

CDH19 ADCY3

2.03e-0318916246e9a58aacd79db5a02898a8c7244e1884adcfd1
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FZD6 SLCO1B3

2.03e-03189162fccadf8efbef17b7f12291b069c71060a71b04e2
ToppCellRA-14._Fibroblast_III|World / Chamber and Cluster_Paper

CDH19 ADCY3

2.03e-03189162b6e12d24d2b0735730bdc625f8318c1c9c2a9b3b
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CDH19 ADCY3

2.05e-031901624eb92aef1ee868f4537483d19014d947b7684612
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CDH19 ADCY3

2.05e-031901627be4341e2909101d756f14031c21e705eb45e69a
ToppCellLV-01._Fibroblast_I|World / Chamber and Cluster_Paper

CDH19 C7

2.05e-0319016212992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY3 C7

2.05e-0319016270c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_B-Plasma_cell|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SEC61G SYVN1

2.07e-03191162fca19f2719806f3dc2dd2add7252ab1198548f4d
Diseasebilirubin metabolic disorder (implicated_via_orthology)

SLCO1B7 SLCO1B3

2.41e-065152DOID:2741 (implicated_via_orthology)
Diseasehexadecenedioate (C16:1-DC) measurement

SLCO1B7 SLCO1B3

8.67e-069152EFO_0800562
Diseaseglycochenodeoxycholate glucuronide (1) measurement

SLCO1B7 SLCO1B3

1.88e-0513152EFO_0800474
DiseaseX-21441 measurement

SLCO1B7 SLCO1B3

3.27e-0517152EFO_0800814
Diseasecreatine measurement

SLCO1B7 SLCO1B3

1.50e-0436152EFO_0010472
Diseasecholestasis (biomarker_via_orthology)

SLCO1B7 SLCO1B3

2.80e-0449152DOID:13580 (biomarker_via_orthology)
Diseasechemokine (C-C motif) ligand 27 measurement

SLCO1B7 SLCO1B3

5.71e-0470152EFO_0008082
Diseasecomplement factor D measurement

XKR3 C7

1.00e-0393152EFO_0020283
Diseaseobsessive-compulsive disorder

SLCO1B3 SEC61G

1.16e-03100152EFO_0004242
DiseaseCrohn's disease

ADCY3 TMEM174 SYVN1

1.32e-03441153EFO_0000384

Protein segments in the cluster

PeptideGeneStartEntry
KIGKMLIFGAIFGCL

DHX29

1081

Q7Z478
GLFTIEMVLKIIAFK

CACNA1F

1231

O60840
AMVIAFVGIFLGKLR

TMEM63C

696

Q9P1W3
VVVLYKKVIIAFGFM

KAT14

676

Q9H8E8
KKLFNIIILGVAFMF

MFSD11

6

O43934
KKFMIRIGVFSGLYL

FZD6

411

O60353
MKVISLFILVGFIGE

C7

1

P10643
IFVKGKGELLTFFLK

ADCY3

1106

O60266
MIIFGFIFLTLGLKQ

CDH19

606

Q9H159
FVLVFLLGKVMGKVF

SYVN1

51

Q86TM6
IGMFSGGYIIKKFKL

SLCO1B7

341

G3V0H7
IMGFIGFFVKLIHIP

SEC61G

46

P60059
FLGGFIIKKFKLSLV

SLCO1B3

391

Q9NPD5
VGVTFILIAVCKFKM

TMEM174

81

Q8WUU8
VIMILVFRFFGGKTL

XKR3

356

Q5GH77
VIMVLVFKFFGVKVL

XKRX

361

Q6PP77