Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SLC6A6 SLC6A8 TPCN2 SLC4A7 HCN4 HCN1 SCN4A SHROOM2	6.74e-07	171	85	8	GO:0015081
GeneOntologyMolecularFunction	sodium channel activity	TPCN2 HCN4 HCN1 SCN4A SHROOM2	2.76e-06	52	85	5	GO:0005272
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	TPCN2 HCN4 HCN1 SCN4A	4.26e-06	26	85	4	GO:0005248
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	SLC6A6 SLC6A8 TPCN2 SLC4A7 KCNC1 HCN4 HCN1 SCN4A GRIN3B SHROOM2 SLC12A5	4.39e-06	465	85	11	GO:0046873
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	SLC6A6 SLC6A8 TPCN2 SLC4A7 KCNC1 HCN4 HCN1 SCN4A GRIN3B SHROOM2 UNC80 SLC12A5	2.37e-05	664	85	12	GO:0008324
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	SLC6A6 SLC6A8 TPCN2 SLC4A7 KCNC1 HCN4 HCN1 SCN4A GRIN3B SHROOM2 SLC12A5	6.95e-05	627	85	11	GO:0022890
GeneOntologyMolecularFunction	monoatomic cation channel activity	TPCN2 KCNC1 HCN4 HCN1 SCN4A GRIN3B SHROOM2 UNC80	1.06e-04	343	85	8	GO:0005261
GeneOntologyMolecularFunction	chloride:monoatomic cation symporter activity	SLC6A6 SLC6A8 SLC12A5	1.24e-04	23	85	3	GO:0015377
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	SLC6A6 SLC6A8 TPCN2 SLC4A7 KCNC1 HCN4 HCN1 SCN4A GRIN3B SHROOM2 UNC80 SLC12A5	1.30e-04	793	85	12	GO:0015075
GeneOntologyMolecularFunction	monoatomic anion:monoatomic cation symporter activity	SLC6A6 SLC6A8 SLC12A5	1.80e-04	26	85	3	GO:0015296
GeneOntologyMolecularFunction	fibroblast growth factor receptor binding	KL FRS3 FRS2	2.51e-04	29	85	3	GO:0005104
GeneOntologyMolecularFunction	gamma-aminobutyric acid:sodium:chloride symporter activity	SLC6A6 SLC6A8	2.66e-04	6	85	2	GO:0005332
GeneOntologyMolecularFunction	beta-glucosidase activity	KL LCT	2.66e-04	6	85	2	GO:0008422
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	SLC6A6 SLC6A8 TPCN2 SLC4A7 KCNC1 HCN4 HCN1 SCN4A GRIN3B SHROOM2 SLC12A5	3.62e-04	758	85	11	GO:0015318
GeneOntologyMolecularFunction	intracellularly ligand-gated monoatomic ion channel activity	TPCN2 HCN4 HCN1	3.70e-04	33	85	3	GO:0005217
GeneOntologyMolecularFunction	channel activity	TPCN2 KCNC1 HCN4 HCN1 SCN4A GRIN3B SHROOM2 UNC80 SLC12A5	3.92e-04	525	85	9	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	TPCN2 KCNC1 HCN4 HCN1 SCN4A GRIN3B SHROOM2 UNC80 SLC12A5	3.97e-04	526	85	9	GO:0022803
GeneOntologyMolecularFunction	cyclic nucleotide binding	HCN4 HCN1 PRKG1	6.09e-04	39	85	3	GO:0030551
GeneOntologyMolecularFunction	gamma-aminobutyric acid transmembrane transporter activity	SLC6A6 SLC6A8	6.32e-04	9	85	2	GO:0015185
GeneOntologyMolecularFunction	monoatomic ion channel activity	TPCN2 KCNC1 HCN4 HCN1 SCN4A GRIN3B SHROOM2 UNC80	7.51e-04	459	85	8	GO:0005216
GeneOntologyMolecularFunction	intracellularly cAMP-activated cation channel activity	HCN4 HCN1	7.88e-04	10	85	2	GO:0005222
GeneOntologyMolecularFunction	G-protein alpha-subunit binding	IGF2R HTR2B RGS22	8.12e-04	43	85	3	GO:0001965
GeneOntologyMolecularFunction	growth factor receptor binding	KL PSG9 FRS3 FRS2 ITGA5	8.64e-04	173	85	5	GO:0070851
GeneOntologyMolecularFunction	transporter activity	SLC6A6 SLC6A8 TPCN2 SLC4A7 KCNC1 HCN4 PSG9 HCN1 SCN4A ATP8B1 GRIN3B SHROOM2 UNC80 SLC12A5	1.03e-03	1289	85	14	GO:0005215
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	TPCN2 KCNC1 HCN4 HCN1 GRIN3B	1.08e-03	182	85	5	GO:0005244
GeneOntologyMolecularFunction	voltage-gated channel activity	TPCN2 KCNC1 HCN4 HCN1 GRIN3B	1.14e-03	184	85	5	GO:0022832
GeneOntologyMolecularFunction	nuclear export signal receptor activity	XPO6 NUP214	1.15e-03	12	85	2	GO:0005049
GeneOntologyMolecularFunction	intracellularly cyclic nucleotide-activated monoatomic cation channel activity	HCN4 HCN1	1.35e-03	13	85	2	GO:0005221
GeneOntologyMolecularFunction	cyclic nucleotide-activated monoatomic ion channel activity	HCN4 HCN1	1.35e-03	13	85	2	GO:0043855
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC6A6 SLC6A8 TPCN2 SLC4A7 KCNC1 HCN4 PSG9 HCN1 SCN4A GRIN3B SHROOM2 UNC80 SLC12A5	1.40e-03	1180	85	13	GO:0022857
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity	TPCN2 HCN4 HCN1 GRIN3B SHROOM2	1.41e-03	193	85	5	GO:0015276
GeneOntologyMolecularFunction	ligand-gated channel activity	TPCN2 HCN4 HCN1 GRIN3B SHROOM2	1.54e-03	197	85	5	GO:0022834
GeneOntologyMolecularFunction	solute:monoatomic cation symporter activity	SLC6A6 SLC6A8 SLC4A7 SLC12A5	1.67e-03	119	85	4	GO:0015294
GeneOntologyMolecularFunction	beta-catenin binding	SOX30 MED12L SHROOM2 GSK3B	1.73e-03	120	85	4	GO:0008013
GeneOntologyMolecularFunction	monocarboxylate:sodium symporter activity	SLC6A6 SLC6A8	1.81e-03	15	85	2	GO:0140161
GeneOntologyMolecularFunction	glucosidase activity	KL LCT	1.81e-03	15	85	2	GO:0015926
GeneOntologyMolecularFunction	sodium:chloride symporter activity	SLC6A6 SLC6A8	2.34e-03	17	85	2	GO:0015378
GeneOntologyMolecularFunction	ligand-gated sodium channel activity	TPCN2 SHROOM2	2.62e-03	18	85	2	GO:0015280
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine kinase adaptor activity	FRS3 FRS2	2.62e-03	18	85	2	GO:0005068
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH2 DNAH8	2.62e-03	18	85	2	GO:0008569
GeneOntologyMolecularFunction	secondary active monocarboxylate transmembrane transporter activity	SLC6A6 SLC6A8	2.92e-03	19	85	2	GO:0015355
GeneOntologyMolecularFunction	monoatomic anion:sodium symporter activity	SLC6A6 SLC6A8	2.92e-03	19	85	2	GO:0015373
GeneOntologyMolecularFunction	ligand-gated monoatomic cation channel activity	TPCN2 HCN4 HCN1 SHROOM2	3.02e-03	140	85	4	GO:0099094
GeneOntologyMolecularFunction	gated channel activity	TPCN2 KCNC1 HCN4 HCN1 GRIN3B SHROOM2	3.02e-03	334	85	6	GO:0022836
GeneOntologyMolecularFunction	microtubule motor activity	APPBP2 DNAH2 DNAH8	3.32e-03	70	85	3	GO:0003777
GeneOntologyMolecularFunction	hydrolase activity, acting on glycosyl bonds	KL OTOGL TLR2 LCT	3.34e-03	144	85	4	GO:0016798
GeneOntologyMolecularFunction	symporter activity	SLC6A6 SLC6A8 SLC4A7 SLC12A5	3.87e-03	150	85	4	GO:0015293
GeneOntologyMolecularFunction	tau-protein kinase activity	CSNK1D GSK3B	3.91e-03	22	85	2	GO:0050321
GeneOntologyMolecularFunction	monoatomic anion transmembrane transporter activity	SLC6A6 SLC6A8 SLC4A7 SLC12A5	3.96e-03	151	85	4	GO:0008509
GeneOntologyMolecularFunction	voltage-gated monoatomic cation channel activity	TPCN2 KCNC1 HCN4 HCN1	4.05e-03	152	85	4	GO:0022843
GeneOntologyMolecularFunction	amino acid:sodium symporter activity	SLC6A6 SLC6A8	4.28e-03	23	85	2	GO:0005283
GeneOntologyMolecularFunction	solute:sodium symporter activity	SLC6A6 SLC6A8 SLC4A7	5.00e-03	81	85	3	GO:0015370
GeneOntologyMolecularFunction	cAMP binding	HCN4 HCN1	5.04e-03	25	85	2	GO:0030552
GeneOntologyMolecularFunction	potassium ion transmembrane transporter activity	KCNC1 HCN4 HCN1 SLC12A5	5.65e-03	167	85	4	GO:0015079
GeneOntologyMolecularFunction	inorganic anion transmembrane transporter activity	SLC6A6 SLC6A8 SLC4A7 SLC12A5	6.14e-03	171	85	4	GO:0015103
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH2 DNAH8	6.30e-03	28	85	2	GO:0051959
GeneOntologyMolecularFunction	monocarboxylic acid transmembrane transporter activity	SLC6A6 SLC6A8 PSG9	6.70e-03	90	85	3	GO:0008028
GeneOntologyMolecularFunction	amino acid:monoatomic cation symporter activity	SLC6A6 SLC6A8	6.75e-03	29	85	2	GO:0005416
GeneOntologyMolecularFunction	Toll-like receptor binding	PSG9 TLR2	6.75e-03	29	85	2	GO:0035325
GeneOntologyMolecularFunction	nucleocytoplasmic carrier activity	XPO6 NUP214	8.18e-03	32	85	2	GO:0140142
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	SLC6A6 SLC6A8 SLC4A7 PSG9 GRIN3B	8.30e-03	293	85	5	GO:0008514
GeneOntologyMolecularFunction	voltage-gated potassium channel activity	KCNC1 HCN4 HCN1	9.44e-03	102	85	3	GO:0005249
GeneOntologyMolecularFunction	hydrolase activity, hydrolyzing O-glycosyl compounds	KL OTOGL LCT	9.70e-03	103	85	3	GO:0004553
GeneOntologyMolecularFunction	organic acid:sodium symporter activity	SLC6A6 SLC6A8	9.73e-03	35	85	2	GO:0005343
GeneOntologyMolecularFunction	pattern recognition receptor activity	IFIH1 TLR2	9.73e-03	35	85	2	GO:0038187
GeneOntologyMolecularFunction	amino acid transmembrane transporter activity	SLC6A6 SLC6A8 GRIN3B	1.02e-02	105	85	3	GO:0015171
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH2 DNAH8	1.08e-02	37	85	2	GO:0045505
GeneOntologyBiologicalProcess	sodium ion transmembrane transport	SLC6A6 SLC6A8 TPCN2 SLC4A7 HCN4 HCN1 SCN4A SHROOM2	1.76e-06	208	82	8	GO:0035725
GeneOntologyBiologicalProcess	sodium ion transport	SLC6A6 SLC6A8 TPCN2 SLC4A7 HCN4 HCN1 SCN4A SHROOM2	1.37e-05	275	82	8	GO:0006814
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	SLC6A6 SLC6A8 TPCN2 SLC4A7 HTR2B KCNC1 HCN4 HCN1 SCN4A GRIN3B TMBIM6 SHROOM2 UNC80 SLC12A5	1.89e-05	942	82	14	GO:0098655
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	SLC6A6 SLC6A8 TPCN2 SLC4A7 HTR2B KCNC1 HCN4 HCN1 SCN4A ATP8B1 GRIN3B TMBIM6 SHROOM2 UNC80 SLC12A5	2.94e-05	1115	82	15	GO:0034220
GeneOntologyBiologicalProcess	apical protein localization	HCN1 ATP8B1 SHROOM2	3.96e-05	17	82	3	GO:0045176
GeneOntologyBiologicalProcess	proteasome-mediated ubiquitin-dependent protein catabolic process	PSMD6 APPBP2 CSNK1D CSNK1E SOCS4 ANAPC2 GSK3B ANAPC4 AGAP3	4.69e-05	424	82	9	GO:0043161
GeneOntologyBiologicalProcess	inorganic cation transmembrane transport	SLC6A6 SLC6A8 TPCN2 SLC4A7 HTR2B KCNC1 HCN4 HCN1 SCN4A GRIN3B TMBIM6 SHROOM2 SLC12A5	6.67e-05	922	82	13	GO:0098662
GeneOntologyBiologicalProcess	proteasomal protein catabolic process	PSMD6 APPBP2 CSNK1D CSNK1E SOCS4 ANAPC2 UBAC2 GSK3B ANAPC4 AGAP3	8.24e-05	567	82	10	GO:0010498
GeneOntologyBiologicalProcess	response to nerve growth factor	KCNC1 CSNK1D CSNK1E RAPGEF1	1.02e-04	61	82	4	GO:1990089
GeneOntologyBiologicalProcess	metal ion transport	SLC6A6 SLC6A8 TPCN2 SLC4A7 HTR2B KCNC1 HCN4 HCN1 SCN4A GRIN3B TMBIM6 SHROOM2 SLC12A5	1.50e-04	1000	82	13	GO:0030001
GeneOntologyBiologicalProcess	monoatomic cation transport	SLC6A6 SLC6A8 TPCN2 SLC4A7 HTR2B KCNC1 HCN4 HCN1 SCN4A GRIN3B TMBIM6 SHROOM2 UNC80 SLC12A5	1.73e-04	1157	82	14	GO:0006812
GeneOntologyBiologicalProcess	inorganic ion transmembrane transport	SLC6A6 SLC6A8 TPCN2 SLC4A7 HTR2B KCNC1 HCN4 HCN1 SCN4A GRIN3B TMBIM6 SHROOM2 SLC12A5	1.78e-04	1017	82	13	GO:0098660
GeneOntologyCellularComponent	HCN channel complex	HCN4 HCN1	9.98e-05	4	86	2	GO:0098855
Domain	PTBI	IRS4 FRS3 FRS2	1.51e-05	11	86	3	SM00310
Domain	IRS_PTB	IRS4 FRS3 FRS2	2.01e-05	12	86	3	PS51064
Domain	IRS_PTB	IRS4 FRS3 FRS2	3.31e-05	14	86	3	IPR002404
Domain	IRS	IRS4 FRS3 FRS2	3.31e-05	14	86	3	PF02174
Domain	cNMP-bd_CS	HCN4 HCN1 PRKG1	5.05e-05	16	86	3	IPR018488
Domain	Glyco_hydro_1_N_CS	KL LCT	1.25e-04	4	86	2	IPR033132
Domain	Ion_trans_N	HCN4 HCN1	1.25e-04	4	86	2	PF08412
Domain	Ion_trans_N	HCN4 HCN1	1.25e-04	4	86	2	IPR013621
Domain	Glyco_hydro_1_AS	KL LCT	1.25e-04	4	86	2	IPR018120
Domain	Ion_trans_dom	TPCN2 KCNC1 HCN4 HCN1 SCN4A	1.82e-04	114	86	5	IPR005821
Domain	Ion_trans	TPCN2 KCNC1 HCN4 HCN1 SCN4A	1.82e-04	114	86	5	PF00520
Domain	GLYCOSYL_HYDROL_F1_2	KL LCT	2.08e-04	5	86	2	PS00653
Domain	GLYCOSYL_HYDROL_F1_1	KL LCT	2.08e-04	5	86	2	PS00572
Domain	Glyco_hydro_1	KL LCT	2.08e-04	5	86	2	PF00232
Domain	Glyco_hydro_1	KL LCT	2.08e-04	5	86	2	IPR001360
Domain	CNMP_BINDING_1	HCN4 HCN1 PRKG1	4.25e-04	32	86	3	PS00888
Domain	CNMP_BINDING_2	HCN4 HCN1 PRKG1	4.25e-04	32	86	3	PS00889
Domain	cNMP	HCN4 HCN1 PRKG1	5.09e-04	34	86	3	SM00100
Domain	cNMP_binding	HCN4 HCN1 PRKG1	5.09e-04	34	86	3	PF00027
Domain	cNMP-bd_dom	HCN4 HCN1 PRKG1	5.55e-04	35	86	3	IPR000595
Domain	CNMP_BINDING_3	HCN4 HCN1 PRKG1	5.55e-04	35	86	3	PS50042
Domain	DHC_N1	DNAH2 DNAH8	5.76e-04	8	86	2	PF08385
Domain	Dynein_heavy_dom-1	DNAH2 DNAH8	5.76e-04	8	86	2	IPR013594
Domain	cNMP-bd-like	HCN4 HCN1 PRKG1	7.08e-04	38	86	3	IPR018490
Domain	-	HCN4 HCN1 PRKG1	1.40e-03	48	86	3	2.60.120.10
Domain	RmlC-like_jellyroll	HCN4 HCN1 PRKG1	1.67e-03	51	86	3	IPR014710
Domain	Dynein_heavy_chain_D4_dom	DNAH2 DNAH8	1.84e-03	14	86	2	IPR024317
Domain	K_chnl_volt-dep_EAG/ELK/ERG	HCN4 HCN1	1.84e-03	14	86	2	IPR003938
Domain	Dynein_HC_stalk	DNAH2 DNAH8	1.84e-03	14	86	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH2 DNAH8	1.84e-03	14	86	2	IPR013602
Domain	DHC_N2	DNAH2 DNAH8	1.84e-03	14	86	2	PF08393
Domain	MT	DNAH2 DNAH8	1.84e-03	14	86	2	PF12777
Domain	AAA_8	DNAH2 DNAH8	1.84e-03	14	86	2	PF12780
Domain	ATPase_dyneun-rel_AAA	DNAH2 DNAH8	1.84e-03	14	86	2	IPR011704
Domain	Ras_G-nucl-exch_fac_CS	RALGDS RAPGEF1	1.84e-03	14	86	2	IPR019804
Domain	AAA_5	DNAH2 DNAH8	1.84e-03	14	86	2	PF07728
Domain	DHC_fam	DNAH2 DNAH8	2.12e-03	15	86	2	IPR026983
Domain	Dynein_heavy_dom	DNAH2 DNAH8	2.12e-03	15	86	2	IPR004273
Domain	Dynein_heavy	DNAH2 DNAH8	2.12e-03	15	86	2	PF03028
Domain	tRNAsynth_Ia_anticodon-bd	IARS2 CARS2	2.12e-03	15	86	2	IPR009080
Domain	Channel_four-helix_dom	TPCN2 KCNC1 SCN4A	2.31e-03	57	86	3	IPR027359
Domain	-	TPCN2 KCNC1 SCN4A	2.31e-03	57	86	3	1.20.120.350
Domain	HEAT_type_2	PIK3R4 TEX10	2.72e-03	17	86	2	IPR021133
Domain	NA_NEUROTRAN_SYMP_2	SLC6A6 SLC6A8	3.06e-03	18	86	2	PS00754
Domain	SNF	SLC6A6 SLC6A8	3.41e-03	19	86	2	PF00209
Domain	NA_NEUROTRAN_SYMP_1	SLC6A6 SLC6A8	3.41e-03	19	86	2	PS00610
Domain	NA_NEUROTRAN_SYMP_3	SLC6A6 SLC6A8	3.41e-03	19	86	2	PS50267
Domain	Na/ntran_symport	SLC6A6 SLC6A8	3.41e-03	19	86	2	IPR000175
Domain	AA_TRNA_LIGASE_I	IARS2 CARS2	3.41e-03	19	86	2	PS00178
Domain	RasGEFN	RALGDS RAPGEF1	3.77e-03	20	86	2	SM00229
Domain	RasGEF_N	RALGDS RAPGEF1	4.16e-03	21	86	2	PF00618
Domain	Ras-like_Gua-exchang_fac_N	RALGDS RAPGEF1	4.56e-03	22	86	2	IPR000651
Domain	RASGEF_NTER	RALGDS RAPGEF1	4.56e-03	22	86	2	PS50212
Pathway	REACTOME_SIGNALING_BY_TYPE_1_INSULIN_LIKE_GROWTH_FACTOR_1_RECEPTOR_IGF1R	PIK3R4 KL IRS4 FRS2	6.72e-05	47	66	4	MM14885
Pathway	PID_BETA_CATENIN_DEG_PATHWAY	CSNK1D CSNK1E GSK3B	7.61e-05	18	66	3	M31
Pathway	REACTOME_SIGNALING_BY_TYPE_1_INSULIN_LIKE_GROWTH_FACTOR_1_RECEPTOR_IGF1R	PIK3R4 KL IRS4 FRS2	1.16e-04	54	66	4	M27168
Pathway	REACTOME_FRS_MEDIATED_FGFR1_SIGNALING	KL FRS3 FRS2	1.42e-04	22	66	3	MM15239
Pathway	REACTOME_FRS_MEDIATED_FGFR1_SIGNALING	KL FRS3 FRS2	1.62e-04	23	66	3	M27513
Pathway	REACTOME_SIGNALLING_TO_ERKS	RALGDS FRS2 RAPGEF1	2.36e-04	26	66	3	MM14716
Pathway	REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR1	KL FRS3 FRS2	3.64e-04	30	66	3	MM15236
Pathway	WP_ANGIOPOIETINLIKE_PROTEIN_8_REGULATORY_PATHWAY	PIK3R4 FASN IRS4 RAPGEF1 GSK3B	3.77e-04	132	66	5	M39338
Pathway	REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR1	KL FRS3 FRS2	4.01e-04	31	66	3	M27510
Pathway	WP_TYPE_I_INTERFERON_INDUCTION_AND_SIGNALING_DURING_SARSCOV2_INFECTION	IFIH1 IRF9 TLR2	4.01e-04	31	66	3	M39859
Pathway	KEGG_INSULIN_SIGNALING_PATHWAY	FASN IRS4 SOCS4 RAPGEF1 GSK3B	4.48e-04	137	66	5	M18155
Pubmed	Association of genetic variation in genes implicated in the beta-catenin destruction complex with risk of breast cancer.	CSNK1D CSNK1E GSK3B	3.11e-07	6	88	3	18708403
Pubmed	Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex.	CSNK1D CSNK1E GSK3B	3.11e-07	6	88	3	11818547
Pubmed	SPOP-mediated ubiquitination and degradation of PDK1 suppresses AKT kinase activity and oncogenic functions.	CSNK1D CSNK1E GSK3B	5.44e-07	7	88	3	34353330
Pubmed	Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway.	CSNK1D CSNK1E GSK3B	5.44e-07	7	88	3	12000790
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	FASN IGF2R XPO6 ANAPC2 DNAH2 UBAC2 FNDC3A PPIL2 NUP214 OTULINL TEX10 GSK3B STT3A	7.16e-07	942	88	13	31073040
Pubmed	FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors.	KL FRS3 FRS2	1.85e-06	10	88	3	10629055
Pubmed	Complex formation and reciprocal regulation between GSK3β and C3G.	RAPGEF1 GSK3B	6.33e-06	2	88	2	33450305
Pubmed	CK1δ and CK1ε are components of human 40S subunit precursors required for cytoplasmic 40S maturation.	CSNK1D CSNK1E	6.33e-06	2	88	2	24424021
Pubmed	Peripheral N- and C-terminal domains determine deactivation kinetics of HCN channels.	HCN4 HCN1	6.33e-06	2	88	2	17548059
Pubmed	Regulation of casein kinase I epsilon and casein kinase I delta by an in vivo futile phosphorylation cycle.	CSNK1D CSNK1E	6.33e-06	2	88	2	9632646
Pubmed	FRS2 family docking proteins with overlapping roles in activation of MAP kinase have distinct spatial-temporal patterns of expression of their transcripts.	FRS3 FRS2	6.33e-06	2	88	2	15094036
Pubmed	Broadly expressed SNT-like proteins link FGF receptor stimulation to activators of Ras.	FRS3 FRS2	6.33e-06	2	88	2	8761293
Pubmed	Upregulation of the creatine transporter Slc6A8 by Klotho.	SLC6A8 KL	6.33e-06	2	88	2	25531216
Pubmed	Regulate axon branching by the cyclic GMP pathway via inhibition of glycogen synthase kinase 3 in dorsal root ganglion sensory neurons.	PRKG1 GSK3B	6.33e-06	2	88	2	19193882
Pubmed	The signaling adapters fibroblast growth factor receptor substrate 2 and 3 are activated by the thyroid TRK oncoproteins.	FRS3 FRS2	6.33e-06	2	88	2	12586769
Pubmed	Casein kinase I delta/epsilon phosphorylates topoisomerase IIalpha at serine-1106 and modulates DNA cleavage activity.	CSNK1D CSNK1E	6.33e-06	2	88	2	19043076
Pubmed	Colocalization of hyperpolarization-activated, cyclic nucleotide-gated channel subunits in rat retinal ganglion cells.	HCN4 HCN1	6.33e-06	2	88	2	21456027
Pubmed	Hyperpolarization-activated channels HCN1 and HCN4 mediate responses to sour stimuli.	HCN4 HCN1	6.33e-06	2	88	2	11675786
Pubmed	Identification of multiple SNT-binding sites on NPM-ALK oncoprotein and their involvement in cell transformation.	FRS3 FRS2	6.33e-06	2	88	2	17086210
Pubmed	Effects of altered expression and activity levels of CK1δ and ɛ on tumor growth and survival of colorectal cancer patients.	CSNK1D CSNK1E	6.33e-06	2	88	2	25404202
Pubmed	Glycogen synthase kinase-3beta (GSK3beta) inhibition suppresses the inflammatory response to Francisella infection and protects against tularemia in mice.	TLR2 GSK3B	6.33e-06	2	88	2	18929413
Pubmed	Neurotrophin and FGF Signaling Adapter Proteins, FRS2 and FRS3, Regulate Dentate Granule Cell Maturation and Excitatory Synaptogenesis.	FRS3 FRS2	6.33e-06	2	88	2	29155277
Pubmed	Molecular composition and functional properties of f-channels in murine embryonic stem cell-derived pacemaker cells.	HCN4 HCN1	6.33e-06	2	88	2	19135060
Pubmed	An evaluation of polymorphisms in casein kinase 1 delta and epsilon genes in major psychiatric disorders.	CSNK1D CSNK1E	6.33e-06	2	88	2	22981886
Pubmed	Genomic organization and comparative sequence analysis of the mouse and human FRS2, FRS3 genes.	FRS3 FRS2	6.33e-06	2	88	2	12688531
Pubmed	USP7 Is a Tumor-Specific WNT Activator for APC-Mutated Colorectal Cancer by Mediating β-Catenin Deubiquitination.	CSNK1D CSNK1E GSK3B	8.56e-06	16	88	3	29045831
Pubmed	Ventricular HCN channels decrease the repolarization reserve in the hypertrophic heart.	HCN4 HCN1	1.90e-05	3	88	2	22652004
Pubmed	Centrosomal anchoring of the protein kinase CK1delta mediated by attachment to the large, coiled-coil scaffolding protein CG-NAP/AKAP450.	CSNK1D CSNK1E	1.90e-05	3	88	2	12270714
Pubmed	Cytoplasmic cAMP-sensing domain of hyperpolarization-activated cation (HCN) channels uses two structurally distinct mechanisms to regulate voltage gating.	HCN4 HCN1	1.90e-05	3	88	2	21187420
Pubmed	Prominent expression of FRS2beta protein in neural cells and its association with intracellular vesicles.	FRS3 FRS2	1.90e-05	3	88	2	19187780
Pubmed	Novel insights into the distribution of cardiac HCN channels: an expression study in the mouse heart.	HCN4 HCN1	1.90e-05	3	88	2	21945247
Pubmed	GSK3β activity alleviates epileptogenesis and limits GluA1 phosphorylation.	HCN4 GSK3B	1.90e-05	3	88	2	30502054
Pubmed	Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.	HCN4 HCN1	1.90e-05	3	88	2	22006928
Pubmed	Novel phosphorylation sites in tau from Alzheimer brain support a role for casein kinase 1 in disease pathogenesis.	CSNK1D GSK3B	1.90e-05	3	88	2	17562708
Pubmed	UNC-51-like kinase regulation of fibroblast growth factor receptor substrate 2/3.	FRS3 FRS2	1.90e-05	3	88	2	16887332
Pubmed	Gene expression levels of Casein kinase 1 (CK1) isoforms are correlated to adiponectin levels in adipose tissue of morbid obese patients and site-specific phosphorylation mediated by CK1 influences multimerization of adiponectin.	CSNK1D CSNK1E	1.90e-05	3	88	2	25724478
Pubmed	A comparative study of structural and conformational properties of casein kinase-1 isoforms: insights from molecular dynamics and principal component analysis.	CSNK1D CSNK1E	1.90e-05	3	88	2	25665722
Pubmed	CRISPR-mediated gene targeting of CK1δ/ε leads to enhanced understanding of their role in endocytosis via phosphoregulation of GAPVD1.	CSNK1D CSNK1E	1.90e-05	3	88	2	32321936
Pubmed	Casein kinase 1-epsilon or 1-delta required for Wnt-mediated intestinal stem cell maintenance.	CSNK1D CSNK1E	1.90e-05	3	88	2	28963394
Pubmed	Human Rad17 C-terminal tail is phosphorylated by concerted action of CK1δ/ε and CK2 to promote interaction with the 9-1-1 complex.	CSNK1D CSNK1E	1.90e-05	3	88	2	31353086
Pubmed	Sequence analysis of the cDNA for the human casein kinase I delta (CSNK1D) gene and its chromosomal localization.	CSNK1D CSNK1E	1.90e-05	3	88	2	8786104
Pubmed	Severity of doxorubicin-induced small intestinal mucositis is regulated by the TLR-2 and TLR-9 pathways.	TLR2 GSK3B	1.90e-05	3	88	2	21960132
Pubmed	Targeting of the circadian clock via CK1δ/ε to improve glucose homeostasis in obesity.	CSNK1D CSNK1E	1.90e-05	3	88	2	27439882
Pubmed	HCN channels in the mammalian cochlea: Expression pattern, subcellular location, and age-dependent changes.	HCN4 HCN1	1.90e-05	3	88	2	33181864
Pubmed	Neurotransmitter transporter family including SLC6A6 and SLC6A13 contributes to the 5-aminolevulinic acid (ALA)-induced accumulation of protoporphyrin IX and photodamage, through uptake of ALA by cancerous cells.	SLC6A6 SLC6A8	1.90e-05	3	88	2	24842606
Pubmed	CKIepsilon/delta-dependent phosphorylation is a temperature-insensitive, period-determining process in the mammalian circadian clock.	CSNK1D CSNK1E	1.90e-05	3	88	2	19805222
Pubmed	Casein kinase 1 proteomics reveal prohibitin 2 function in molecular clock.	CSNK1D CSNK1E	1.90e-05	3	88	2	22384121
Pubmed	Direct interaction of Rnd1 with FRS2 beta regulates Rnd1-induced down-regulation of RhoA activity and is involved in fibroblast growth factor-induced neurite outgrowth in PC12 cells.	FRS3 FRS2	1.90e-05	3	88	2	15738000
Pubmed	Polyinosinic-polycytidylic acid treatment of Friend retrovirus-infected mice improves functional properties of virus-specific T cells and prevents virus-induced disease.	IFIH1 TLR2	1.90e-05	3	88	2	20943997
Pubmed	EP3 activation facilitates bladder excitability via HCN channels on ICCs.	HCN4 HCN1	1.90e-05	3	88	2	28131828
Pubmed	FRS2 PTB domain conformation regulates interactions with divergent neurotrophic receptors.	FRS3 FRS2	1.90e-05	3	88	2	11877385
Pubmed	Fibroblast growth factor receptor 1 (FGFR1) tyrosine phosphorylation regulates binding of FGFR substrate 2alpha (FRS2alpha) but not FRS2 to the receptor.	FRS3 FRS2	1.90e-05	3	88	2	17901128
Pubmed	A New alpha5beta1 integrin-dependent survival pathway through GSK3beta activation in leukemic cells.	ITGA5 GSK3B	1.90e-05	3	88	2	20352103
Pubmed	Involvement of casein kinase 1 epsilon/delta (Csnk1e/d) in the pathogenesis of familial Parkinson's disease caused by CHCHD2.	CSNK1D CSNK1E	3.79e-05	4	88	2	37578019
Pubmed	Functional expression of the human HCN3 channel.	HCN4 HCN1	3.79e-05	4	88	2	16043489
Pubmed	The DNA-binding activity of mouse DNA methyltransferase 1 is regulated by phosphorylation with casein kinase 1delta/epsilon.	CSNK1D CSNK1E	3.79e-05	4	88	2	20192920
Pubmed	Interactive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein, with homology to eag and cyclic nucleotide-gated channels.	HCN4 HCN1	3.79e-05	4	88	2	9405696
Pubmed	Role of subunit heteromerization and N-linked glycosylation in the formation of functional hyperpolarization-activated cyclic nucleotide-gated channels.	HCN4 HCN1	3.79e-05	4	88	2	12928435
Pubmed	Therapeutic Targeting of Casein Kinase 1δ/ε in an Alzheimer's Disease Mouse Model.	CSNK1D CSNK1E	3.79e-05	4	88	2	31334659
Pubmed	The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling.	CSNK1E GSK3B	3.79e-05	4	88	2	12183362
Pubmed	Hyperpolarization-activated and cyclic nucleotide-gated channels are differentially expressed in juxtaglomerular cells in the olfactory bulb of mice.	HCN4 HCN1	3.79e-05	4	88	2	20140458
Pubmed	Casein kinase 1 delta (CK1delta) regulates period length of the mouse suprachiasmatic circadian clock in vitro.	CSNK1D CSNK1E	3.79e-05	4	88	2	20421981
Pubmed	Investigation of hyperpolarization-activated cyclic nucleotide-gated channels in interstitial cells of Cajal of human bladder.	HCN4 HCN1	3.79e-05	4	88	2	22748890
Pubmed	Involvement of casein kinase Iepsilon in cytokine-induced granulocytic differentiation.	CSNK1D CSNK1E	3.79e-05	4	88	2	15070676
Pubmed	Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain.	HCN4 HCN1	3.79e-05	4	88	2	9630217
Pubmed	cGMP-dependent protein kinase I interacts with TRIM39R, a novel Rpp21 domain-containing TRIM protein.	RPP21 PRKG1	3.79e-05	4	88	2	17601797
Pubmed	CK1δ/ε protein kinase primes the PER2 circadian phosphoswitch.	CSNK1D CSNK1E	3.79e-05	4	88	2	29784789
Pubmed	MDA5 and ISG56 mediate CXCL10 expression induced by toll-like receptor 4 activation in U373MG human astrocytoma cells.	IFIH1 TLR2	3.79e-05	4	88	2	23684765
Pubmed	Casein kinase 1 delta functions at the centrosome to mediate Wnt-3a-dependent neurite outgrowth.	CSNK1D CSNK1E	3.79e-05	4	88	2	21422228
Pubmed	Protein kinase G-dependent cardioprotective mechanism of phosphodiesterase-5 inhibition involves phosphorylation of ERK and GSK3beta.	PRKG1 GSK3B	3.79e-05	4	88	2	18723505
Pubmed	Genetic analysis of hyperpolarization-activated cyclic nucleotide-gated cation channels in sudden unexpected death in epilepsy cases.	HCN4 HCN1	3.79e-05	4	88	2	21615589
Pubmed	p53 is phosphorylated in vitro and in vivo by the delta and epsilon isoforms of casein kinase 1 and enhances the level of casein kinase 1 delta in response to topoisomerase-directed drugs.	CSNK1D CSNK1E	3.79e-05	4	88	2	9349507
Pubmed	Isolation and characterization of human casein kinase I epsilon (CKI), a novel member of the CKI gene family.	CSNK1D CSNK1E	3.79e-05	4	88	2	7797465
Pubmed	CK1δ/GSK3β/FBXW7α axis promotes degradation of the ZNF322A oncoprotein to suppress lung cancer progression.	CSNK1D GSK3B	3.79e-05	4	88	2	28581525
Pubmed	Developmental expression patterns of the signaling adapters FRS-2 and FRS-3 during early embryogenesis.	FRS3 FRS2	3.79e-05	4	88	2	11335123
Pubmed	Regulation of the nuclear export of the transcription factor NFATc1 by protein kinases after slow fibre type electrical stimulation of adult mouse skeletal muscle fibres.	CSNK1E GSK3B	3.79e-05	4	88	2	17185343
Pubmed	Novel recognition motif on fibroblast growth factor receptor mediates direct association and activation of SNT adapter proteins.	FRS3 FRS2	3.79e-05	4	88	2	9660748
Pubmed	Phosphorylation of human enhancer filamentation 1 (HEF1) stimulates interaction with Polo-like kinase 1 leading to HEF1 localization to focal adhesions.	CSNK1D CSNK1E	6.30e-05	5	88	2	29191835
Pubmed	Regulation of HCN channel surface expression by a novel C-terminal protein-protein interaction.	HCN4 HCN1	6.30e-05	5	88	2	15564593
Pubmed	Casein kinase 1 delta regulates the pace of the mammalian circadian clock.	CSNK1D CSNK1E	6.30e-05	5	88	2	19414593
Pubmed	Microbial pattern recognition receptors mediate M-cell uptake of a gram-negative bacterium.	TLR2 ITGA5	6.30e-05	5	88	2	16369019
Pubmed	Nuclear entry of the circadian regulator mPER1 is controlled by mammalian casein kinase I epsilon.	CSNK1D CSNK1E	6.30e-05	5	88	2	10848614
Pubmed	Developmental HCN channelopathy results in decreased neural progenitor proliferation and microcephaly in mice.	HCN4 HCN1	6.30e-05	5	88	2	34429357
Pubmed	Desynchrony between brain and peripheral clocks caused by CK1δ/ε disruption in GABA neurons does not lead to adverse metabolic outcomes.	CSNK1D CSNK1E	6.30e-05	5	88	2	29463694
Pubmed	The CK1δ/ε-AES axis regulates tumorigenesis and metastasis in colorectal cancer.	CSNK1D CSNK1E	6.30e-05	5	88	2	33754069
Pubmed	Essential roles of CKIdelta and CKIepsilon in the mammalian circadian clock.	CSNK1D CSNK1E	6.30e-05	5	88	2	19948962
Pubmed	Four proline-rich sequences of the guanine-nucleotide exchange factor C3G bind with unique specificity to the first Src homology 3 domain of Crk.	FRS2 RAPGEF1	6.30e-05	5	88	2	7806500
Pubmed	Control of intracellular dynamics of mammalian period proteins by casein kinase I epsilon (CKIepsilon) and CKIdelta in cultured cells.	CSNK1D CSNK1E	6.30e-05	5	88	2	11865049
Pubmed	Wnt-3a utilizes a novel low dose and rapid pathway that does not require casein kinase 1-mediated phosphorylation of Dvl to activate beta-catenin.	CSNK1D CSNK1E	6.30e-05	5	88	2	17027228
Pubmed	Context-specific requirements for Fgfr1 signaling through Frs2 and Frs3 during mouse development.	FRS3 FRS2	6.30e-05	5	88	2	16421190
Pubmed	Differential expression of hyperpolarization-activated cyclic nucleotide-gated channel subunits during hippocampal development in the mouse.	HCN4 HCN1	9.43e-05	6	88	2	25761792
Pubmed	Phosphorylation at Ser244 by CK1 determines nuclear localization and substrate targeting of PKD2.	CSNK1D CSNK1E	9.43e-05	6	88	2	17962809
Pubmed	Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex.	CSNK1E GSK3B	9.43e-05	6	88	2	17318175
Pubmed	Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism.	CSNK1D GSK3B	9.43e-05	6	88	2	11955436
Pubmed	Genetic polymorphisms of EPHX1, Gsk3beta, TNFSF8 and myeloma cell DKK-1 expression linked to bone disease in myeloma.	TNFSF8 GSK3B	9.43e-05	6	88	2	19657367
Pubmed	High-throughput chemical screen identifies a novel potent modulator of cellular circadian rhythms and reveals CKIα as a clock regulatory kinase.	CSNK1D CSNK1E	9.43e-05	6	88	2	21179498
Pubmed	A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP).	CSNK1D CSNK1E	9.43e-05	6	88	2	20048001
Pubmed	Physiological role for casein kinase 1 in glutamatergic synaptic transmission.	CSNK1D CSNK1E	9.43e-05	6	88	2	16014721
Pubmed	Identification of a novel Wnt5a-CK1ɛ-Dvl2-Plk1-mediated primary cilia disassembly pathway.	CSNK1D CSNK1E	9.43e-05	6	88	2	22609948
Pubmed	Novel Rap1 dominant-negative mutants interfere selectively with C3G and Epac.	RALGDS RAPGEF1	9.43e-05	6	88	2	15856025
Cytoband	20q13.12	PCIF1 SPINT4 SLC12A5	2.15e-04	60	88	3	20q13.12
Cytoband	9q34.3	RALGDS ANAPC2 RAPGEF1	1.14e-03	106	88	3	9q34.3
Cytoband	12q15	RAB3IP FRS2	1.74e-03	32	88	2	12q15
Cytoband	17q25	FASN CSNK1D	2.57e-03	39	88	2	17q25
GeneFamily	Cyclic nucleotide gated channels	HCN4 HCN1	4.79e-04	10	60	2	250
GeneFamily	Anaphase promoting complex \|Tetratricopeptide repeat domain containing	ANAPC2 ANAPC4	9.61e-04	14	60	2	402
GeneFamily	Dyneins, axonemal	DNAH2 DNAH8	1.43e-03	17	60	2	536
GeneFamily	OTU domain containing	OTULINL ALG13	1.43e-03	17	60	2	669
GeneFamily	Aminoacyl tRNA synthetases, Class I	IARS2 CARS2	1.79e-03	19	60	2	131
Coexpression	GSE40274_FOXP3_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN	IFIH1 IRF9 IGF2R XPO6 TNFSF8 RAB3IP DCAF17 DNAH8	3.35e-07	199	87	8	M9180
Drug	pppAp	CSNK1D CSNK1E LCT GSK3B	1.32e-07	13	86	4	CID000189064
Drug	Cd-B	IRF9 FNDC3A PRKG1 CARS2 F8	4.72e-06	65	86	5	CID000447221
Drug	estradiol, USP; Down 200; 0.01uM; PC3; HG-U133A	SLC6A6 APPBP2 SLC4A7 FNDC3A CHST2 OTULINL SHROOM2	1.09e-05	200	86	7	665_DN
Drug	AC1NDT8A	RALGDS SRGAP3 FRS2 FNDC3A	1.14e-05	37	86	4	CID004631218
Disease	Myocardial Failure	FASN HTR2B TLR2 APCS GSK3B	1.60e-05	110	84	5	C1959583
Disease	Congestive heart failure	FASN HTR2B TLR2 APCS GSK3B	1.60e-05	110	84	5	C0018802
Disease	Heart failure	FASN HTR2B TLR2 APCS GSK3B	1.60e-05	110	84	5	C0018801
Disease	Left-Sided Heart Failure	FASN HTR2B TLR2 APCS GSK3B	1.60e-05	110	84	5	C0023212
Disease	Heart Failure, Right-Sided	FASN HTR2B TLR2 APCS GSK3B	1.60e-05	110	84	5	C0235527
Disease	Heart Decompensation	FASN HTR2B TLR2 APCS GSK3B	1.60e-05	110	84	5	C1961112
Disease	sick sinus syndrome (implicated_via_orthology)	HCN4 HCN1	2.40e-05	3	84	2	DOID:13884 (implicated_via_orthology)
Disease	liposarcoma	FASN FRS2	1.19e-04	6	84	2	C0023827
Disease	syndromic X-linked intellectual disability Najm type (implicated_via_orthology)	CSNK1D CSNK1E	1.67e-04	7	84	2	DOID:0060807 (implicated_via_orthology)
Disease	memory performance	HCN1 PCIF1 FNDC3A TSHB PRKG1 ARMC2 ANAPC4	1.69e-04	409	84	7	EFO_0004874
Disease	skin microbiome measurement	KL SRGAP3 OTULINL	1.89e-04	39	84	3	EFO_0801228
Disease	Malignant neoplasm of breast	PIK3R4 FASN OTOGL CSNK1D SRGAP3 APCS NUP214 ATP8B1 SIM1 SHROOM2 GPR45	2.31e-04	1074	84	11	C0006142
Disease	Intellectual Disability	SLC6A8 RALGDS FASN SRGAP3 MED12L STT3A ALG13	2.90e-04	447	84	7	C3714756
Disease	selective IgA deficiency disease	IFIH1 FASN PRKG1	3.09e-04	46	84	3	EFO_1001929
Disease	APOE carrier status, dementia	TPCN2 PPIL2 PRKG1	7.46e-04	62	84	3	EFO_0007659, MONDO_0001627
Disease	Coronary Arteriosclerosis	KL HECTD4 APCS	8.56e-04	65	84	3	C0010054
Disease	Coronary Artery Disease	KL HECTD4 APCS	8.56e-04	65	84	3	C1956346
Disease	Colorectal Carcinoma	RALGDS KL IRS4 TLR2 CAMSAP2 DNAH8 ANAPC4 SLC12A5	8.77e-04	702	84	8	C0009402
Disease	5-oxoproline measurement	PRKG1 DNAH8	9.36e-04	16	84	2	EFO_0010988
Disease	susceptibility to mononucleosis measurement	DNAH2 DNAH8 ANAPC4	1.02e-03	69	84	3	EFO_0008403
Disease	intellectual disability (implicated_via_orthology)	IRS4 ATF7IP2 ITGA5	1.30e-03	75	84	3	DOID:1059 (implicated_via_orthology)
Disease	Manic	TSHB DNAH8 GSK3B	1.45e-03	78	84	3	C0338831
Disease	Epilepsy, Cryptogenic	HCN1 SLC12A5 ALG13	1.68e-03	82	84	3	C0086237
Disease	Awakening Epilepsy	HCN1 SLC12A5 ALG13	1.68e-03	82	84	3	C0751111
Disease	Aura	HCN1 SLC12A5 ALG13	1.68e-03	82	84	3	C0236018
Disease	S-warfarin measurement	SLC6A6 HCN1 ADAM7	2.71e-03	97	84	3	EFO_0803323
Disease	Alzheimer disease, APOE carrier status	TPCN2 PPIL2 PRKG1	2.79e-03	98	84	3	EFO_0007659, MONDO_0004975

Protein segments in the cluster

Peptide	Gene	Start	Entry
YNYFLRLCSFRNASE	AGAP3	176	Q96P47
IYFDNYRRCVSSVAS	DCAF17	66	Q5H9S7
TFRDAFGRYITCNYR	HTR2B	386	P41595
CQSYDNFSYRSRSFR	ALG13	686	Q9NP73
VRRSIYSCLDAQFYD	ANAPC4	631	Q9UJX5
CHVQRFFYRIYASLR	ANAPC2	326	Q9UJX6
RSREFLGSNYSETFY	ADAM7	76	Q9H2U9
LASYSRCYALFLNLI	ARMC2	511	Q8NEN0
VLAYSFSRRCSYIAE	APPBP2	96	Q92624
SSDYSFAQFRYLQRL	ATP8B1	921	O43520
NRSQFFITFRSCAYL	PPIL2	376	Q13356
RITSVCNFFTYIRYI	RAB3IP	426	Q96QF0
ALSYTRCAAQFFLFT	OR9Q1	91	Q8NGQ5
QSAYLSRRLAYFCAR	MED12L	286	Q86YW9
FLCSNADRDQATYYR	GLIPR1L2	221	Q4G1C9
TRFYTACVVEAFAYL	PRKG1	461	Q13976
YQLFRNLFCSYGLTE	ERVMER34-1	241	Q9H9K5
SESCESYFQRYRRRA	DNAH8	3021	Q96JB1
SEFATYLNFCRSLRF	CSNK1D	246	P48730
FIRATADVFCLNTYY	LCT	1196	P09848
SLSRSAFLSQRYYED	NUP214	966	P35658
FCFSATRRYYLGAVE	F8	16	P00451
AHRLCRQFSTYFRYG	LRGUK	431	Q96M69
YFFLRNLSFADLCFS	OR2D3	76	Q8NGH3
LYLRFDSRCSSQYDY	HECTD4	661	Q9Y4D8
YSLLSVFSQRFYCGS	GPR45	286	Q9Y5Y3
DTYCRLYSLSVDNFN	HCN4	676	Q9Y3Q4
VFSCLSLRLRAAFFY	PAQR9	141	Q6ZVX9
SLRLRAAFFYLDYAS	PAQR9	146	Q6ZVX9
FRLFKFNSRDFEVCY	OTULINL	316	Q9NUU6
CYLSTDNFTRILEYA	ITGA5	176	P08648
DTYCRLYSLSVDNFN	HCN1	556	O60741
SRYARYVAFASLFFI	KCNC1	186	P48547
YRYSCIDDSAFERFL	PCIF1	451	Q9H4Z3
SSFRYSSLQLNCEYR	FNDC3A	1101	Q9Y2H6
CLRRYGYDSNLFSFE	FRS2	61	Q8WU20
CLRRYGYDSNLFSFE	FRS3	61	O43559
STDENFRYLISCFRA	IFIH1	6	Q9BYX4
HCNIVRLRYFFYSSG	GSK3B	106	P49841
TCFTLSALYARRRSY	TMBIM6	126	P55061
CTLSQFLASNRYYFT	ATF7IP2	641	Q5U623
DLSYVTIFLCTYRAF	RALGDS	136	Q12967
ELFRTAYFCRDLVRY	IRF9	321	Q00978
YTALAFAEYARLCFQ	KL	661	Q9UEF7
FLFSLCEYLNAYSGR	CENPO	176	Q9BU64
LSFAARSFYYKLRAA	FASN	2416	P49327
HTYAVYRYTCRTLFE	DNAH2	3666	Q9P225
RLLTTYINDYFCDQS	DNAH2	4056	Q9P225
LFRDSGCQFRSLYTY	CAMSAP2	1401	Q08AD1
GFLRRYTFNILFCTS	NPIPB9	81	F8W1W9
VRQYLFSLYECRYSV	PSMD6	256	Q15008
FSLYECRYSVFFQSL	PSMD6	261	Q15008
LGSVYSCYRSISLFF	OTOGL	171	Q3ZCN5
SSRFLNATCDEYFTR	SLC12A5	346	Q9H2X9
YQCFSVSQRADARYR	IRS4	151	O14654
YSSALNLCYAILFRR	GRIN3B	616	O60391
LYTSRACYNLFILSF	GPR137B	246	O60478
KVYQRSTAIFFYCDR	IGF2R	1321	P11717
RFFCLRSSYRSAIDY	CARS2	341	Q9HA77
YRREIFIAFVCSISY	SLC6A6	426	P31641
FCRDYQLSYLSLRTS	SLC4A7	681	Q9Y6M7
FYYCINTTTSERFDI	SCN4A	1186	P35499
TCEEFLSSYIYFILR	RGS22	311	Q8NE09
FTYYRSGENLDLSCF	PSG9	341	Q00887
EDYLFSVSFRRYSRS	SOCS4	316	Q8WXH5
FNYFYGISLTNLRDC	STS	156	P08842
YYCFSNLSDARIFII	STT3A	376	P46977
NQALARFYCYTERTI	RPP21	31	Q9H633
YRQFSDRSSLCYGFA	SIM1	436	P81133
STSEQFYSRFCLYTR	SHROOM2	1251	Q13796
FYAFLASKFCEYERR	NOM1	706	Q5C9Z4
LRTFYTRELSNFYFS	IARS2	786	Q9NSE4
SYYFRFQREISVALC	SLC6A8	436	P48029
LNRDYSFRDYSSECT	SOX30	666	O94993
SALYRCDLSVFQLYS	CHST2	221	Q9Y4C5
ADFNYFFDTSRRRTC	PIK3R4	181	Q99570
RSYFYLTTATLALCL	TNFSF8	36	P32971
CQRSRYATYFDVAVL	UNC80	321	Q8N2C7
SLARTFRTYLSAEYN	SRGAP3	276	O43295
EYCTLIDSSSSFRAY	RAPGEF1	956	Q13905
NFTLCFRAYSDLSRA	APCS	51	P02743
FRAYSDLSRAYSLFS	APCS	56	P02743
RYFYNRTSKRCETFV	SPINT4	56	Q6UDR6
QFCLSYNDYLSRLTV	SYT15B	336	X6R8R1
YQTEELRSCRFRYRS	TEX10	531	Q9NXF1
ALSQDVCTYRDFIYR	TSHB	66	P01222
ACFSLSLTLTYYRTA	ZNF286B	81	P0CG31
FCSSLLIYNFRIFER	UBAC2	71	Q8NBM4
RFCLYFLSSTRNDYV	XPO6	46	Q96QU8
SRNICYDAFVSYSER	TLR2	636	O60603
RYYSNVCQRTLSFTI	TPCN2	76	Q8NHX9
SEFSTYLNFCRSLRF	CSNK1E	246	P49674