Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCC1 ABCA1 ABCA3 CCT3 MYO5B MCM3 CHD8 ABCA6 CHD6 DDX39A DNAH5 DNAH8 SNRNP200 DNAH11

2.33e-0644113814GO:0016887
GeneOntologyMolecularFunctionsmall GTPase binding

UNC13B DOCK4 ABCA1 ANKFY1 RNF152 MYO5B DOCK11 PLEKHG1 RASIP1 XPO5 IPO11

1.47e-0532113811GO:0031267
GeneOntologyMolecularFunctionpyrophosphatase activity

ABCC1 ABCA1 ABCA3 GNG8 RNGTT CCT3 MYO5B MCM3 CHD8 GUF1 RAB33A ABCA6 CHD6 DDX39A DNAH5 DNAH8 SNRNP200 DNAH11

1.96e-0583913818GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

ABCC1 ABCA1 ABCA3 GNG8 RNGTT CCT3 MYO5B MCM3 CHD8 GUF1 RAB33A ABCA6 CHD6 DDX39A DNAH5 DNAH8 SNRNP200 DNAH11

1.99e-0584013818GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

ABCC1 ABCA1 ABCA3 GNG8 RNGTT CCT3 MYO5B MCM3 CHD8 GUF1 RAB33A ABCA6 CHD6 DDX39A DNAH5 DNAH8 SNRNP200 DNAH11

1.99e-0584013818GO:0016818
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

ABCC1 ABCA1 ABCA3 GNG8 CCT3 MYO5B MCM3 CHD8 GUF1 RAB33A ABCA6 CHD6 DDX39A DNAH5 DNAH8 SNRNP200 DNAH11

2.57e-0577513817GO:0017111
GeneOntologyMolecularFunctionGTPase binding

UNC13B DOCK4 ABCA1 ANKFY1 RNF152 MYO5B DOCK11 PLEKHG1 RASIP1 XPO5 IPO11

4.20e-0536013811GO:0051020
GeneOntologyMolecularFunctionATP-dependent activity

ABCC1 ABCA1 ABCA3 CCT3 MYO5B MCM3 CHD8 ABCA6 CHD6 DDX39A DNAH5 DNAH8 SNRNP200 DNAH11

9.23e-0561413814GO:0140657
GeneOntologyMolecularFunctiondynein intermediate chain binding

DYNLT3 DNAH5 DNAH8 DNAH11

1.21e-04371384GO:0045505
GeneOntologyMolecularFunctioncalcium-dependent cysteine-type endopeptidase activity

CAPN3 CAPN8 ADGB

2.05e-04171383GO:0004198
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

DOCK4 DOCK11 DOCK8 PLEKHG1 ARHGEF4 ARHGEF37 PREX1 VAV2

2.08e-042311388GO:0005085
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH5 DNAH8 DNAH11

2.44e-04181383GO:0008569
GeneOntologyMolecularFunctionABC-type transporter activity

ABCC1 ABCA1 ABCA3 ABCA6

3.64e-04491384GO:0140359
GeneOntologyMolecularFunctionribose phosphate diphosphokinase activity

PRPS1L1 PRPS1

4.68e-0451382GO:0004749
GeneOntologyMolecularFunctionankyrin binding

SCN5A KCNQ2 PLEC

5.17e-04231383GO:0030506
GeneOntologyMolecularFunctiondiphosphotransferase activity

PRPS1L1 PRPS1

6.98e-0461382GO:0016778
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH5 DNAH8 DNAH11

9.32e-04281383GO:0051959
GeneOntologyMolecularFunctionnucleocytoplasmic carrier activity

RANBP6 XPO5 IPO11

1.38e-03321383GO:0140142
DomainAAA

ABCC1 ABCA1 ABCA3 MCM3 ABCA6 DNAH5 DNAH8 SNRNP200 DNAH11

1.24e-061441389SM00382
DomainAAA+_ATPase

ABCC1 ABCA1 ABCA3 MCM3 ABCA6 DNAH5 DNAH8 SNRNP200 DNAH11

1.24e-061441389IPR003593
DomainARM-type_fold

SMG1 DOCK11 DOCK8 UBR4 RANBP6 CLASP2 XPO5 PIK3CD ASPM ATM EIF4G3 HEATR3 IPO11

1.42e-0633913813IPR016024
DomainHEAT_REPEAT

SMG1 RANBP6 CLASP2 EIF4G3 HEATR3 IPO11

1.30e-05701386PS50077
DomainDHC_N1

DNAH5 DNAH8 DNAH11

2.15e-0581383PF08385
DomainDynein_heavy_dom-1

DNAH5 DNAH8 DNAH11

2.15e-0581383IPR013594
DomainPept_cys_AS

CAPN3 CAPN8 DNAH8 CTSS

5.09e-05281384IPR000169
DomainATM/Tel1

SMG1 ATM

5.42e-0521382IPR015519
DomainDHR-1_domain

DOCK4 DOCK11 DOCK8

6.24e-05111383IPR027007
DomainDHR_2

DOCK4 DOCK11 DOCK8

6.24e-05111383PS51651
DomainDHR_1

DOCK4 DOCK11 DOCK8

6.24e-05111383PS51650
DomainDHR-2

DOCK4 DOCK11 DOCK8

6.24e-05111383PF06920
DomainDOCK

DOCK4 DOCK11 DOCK8

6.24e-05111383IPR026791
DomainDOCK_C

DOCK4 DOCK11 DOCK8

6.24e-05111383IPR010703
DomainDOCK-C2

DOCK4 DOCK11 DOCK8

6.24e-05111383PF14429
DomainDHR-2

DOCK4 DOCK11 DOCK8

6.24e-05111383IPR027357
DomainHEAT

RANBP6 CLASP2 EIF4G3 HEATR3 IPO11

6.85e-05581385IPR000357
DomainABC_A

ABCA1 ABCA3 ABCA6

8.27e-05121383IPR026082
DomainDH_1

PLEKHG1 ARHGEF4 ARHGEF37 PREX1 VAV2

1.02e-04631385PS00741
DomainDynein_heavy_chain_D4_dom

DNAH5 DNAH8 DNAH11

1.35e-04141383IPR024317
DomainDynein_HC_stalk

DNAH5 DNAH8 DNAH11

1.35e-04141383IPR024743
DomainDynein_heavy_dom-2

DNAH5 DNAH8 DNAH11

1.35e-04141383IPR013602
DomainDHC_N2

DNAH5 DNAH8 DNAH11

1.35e-04141383PF08393
DomainATPase_dyneun-rel_AAA

DNAH5 DNAH8 DNAH11

1.35e-04141383IPR011704
DomainMT

DNAH5 DNAH8 DNAH11

1.35e-04141383PF12777
DomainAAA_8

DNAH5 DNAH8 DNAH11

1.35e-04141383PF12780
DomainAAA_5

DNAH5 DNAH8 DNAH11

1.35e-04141383PF07728
DomainRhoGEF

PLEKHG1 ARHGEF4 ARHGEF37 PREX1 VAV2

1.47e-04681385SM00325
DomainPRPP_SYNTHASE

PRPS1L1 PRPS1

1.62e-0431382PS00114
DomainPRib_PP_synth_CS

PRPS1L1 PRPS1

1.62e-0431382IPR000842
DomainDHC_fam

DNAH5 DNAH8 DNAH11

1.68e-04151383IPR026983
DomainPeptidase_C2

CAPN3 CAPN8 ADGB

1.68e-04151383PF00648
DomainDynein_heavy

DNAH5 DNAH8 DNAH11

1.68e-04151383PF03028
DomainPI3/4_kinase_CS

SMG1 PIK3CD ATM

1.68e-04151383IPR018936
DomainCysPc

CAPN3 CAPN8 ADGB

1.68e-04151383SM00230
DomainPeptidase_C2_calpain_cat

CAPN3 CAPN8 ADGB

1.68e-04151383IPR001300
DomainDynein_heavy_dom

DNAH5 DNAH8 DNAH11

1.68e-04151383IPR004273
DomainCALPAIN_CAT

CAPN3 CAPN8 ADGB

1.68e-04151383PS50203
DomainRhoGEF

PLEKHG1 ARHGEF4 ARHGEF37 PREX1 VAV2

1.69e-04701385PF00621
DomainDH_2

PLEKHG1 ARHGEF4 ARHGEF37 PREX1 VAV2

1.69e-04701385PS50010
Domain-

PLEKHG1 ARHGEF4 ARHGEF37 PREX1 VAV2

1.80e-047113851.20.900.10
DomainDH-domain

PLEKHG1 ARHGEF4 ARHGEF37 PREX1 VAV2

1.80e-04711385IPR000219
DomainGDS_CDC24_CS

PLEKHG1 ARHGEF4 PREX1 VAV2

1.92e-04391384IPR001331
Domain-

SMG1 PIK3CD ATM

2.06e-041613831.10.1070.11
DomainPI3Kc

SMG1 PIK3CD ATM

2.06e-04161383SM00146
DomainPI3_PI4_kinase

SMG1 PIK3CD ATM

2.97e-04181383PF00454
DomainPI3_4_KINASE_1

SMG1 PIK3CD ATM

2.97e-04181383PS00915
DomainPI3_4_KINASE_2

SMG1 PIK3CD ATM

2.97e-04181383PS00916
DomainPI3/4_kinase_cat_dom

SMG1 PIK3CD ATM

2.97e-04181383IPR000403
DomainPI3_4_KINASE_3

SMG1 PIK3CD ATM

2.97e-04181383PS50290
DomainABC_tran

ABCC1 ABCA1 ABCA3 ABCA6

4.31e-04481384PF00005
DomainABC_TRANSPORTER_2

ABCC1 ABCA1 ABCA3 ABCA6

4.31e-04481384PS50893
DomainABC_TRANSPORTER_1

ABCC1 ABCA1 ABCA3 ABCA6

4.67e-04491384PS00211
DomainABC_transporter-like

ABCC1 ABCA1 ABCA3 ABCA6

5.05e-04501384IPR003439
DomainP-loop_NTPase

ABCC1 ABCA1 ABCA3 MYO5B MCM3 CHD8 GUF1 RAB33A ABCA6 ASPM CHD6 DDX39A DNAH5 DNAH8 SNRNP200 DNAH11

5.33e-0484813816IPR027417
DomainPribosyltran_N

PRPS1L1 PRPS1

5.34e-0451382PF13793
DomainPribosyl_synth

PRPS1L1 PRPS1

5.34e-0451382PF14572
DomainRib-P_diPkinase

PRPS1L1 PRPS1

5.34e-0451382IPR005946
DomainPribosyltran_N

PRPS1L1 PRPS1

5.34e-0451382IPR029099
DomainFATC

SMG1 ATM

5.34e-0451382PF02260
DomainBRK

CHD8 CHD6

7.97e-0461382SM00592
DomainDilute_dom

MYO5B RASIP1

7.97e-0461382IPR002710
DomainBRK_domain

CHD8 CHD6

7.97e-0461382IPR006576
DomainDUF3398

DOCK11 DOCK8

7.97e-0461382PF11878
DomainDIL

MYO5B RASIP1

7.97e-0461382PF01843
DomainFAT

SMG1 ATM

7.97e-0461382PS51189
DomainFATC

SMG1 ATM

7.97e-0461382PS51190
DomainDILUTE

MYO5B RASIP1

7.97e-0461382PS51126
DomainFATC_dom

SMG1 ATM

7.97e-0461382IPR003152
DomainDOCK_C/D_N

DOCK11 DOCK8

7.97e-0461382IPR021816
DomainPIK_FAT

SMG1 ATM

7.97e-0461382IPR014009
DomainDIL

MYO5B RASIP1

7.97e-0461382SM01132
DomainBRK

CHD8 CHD6

7.97e-0461382PF07533
DomainFATC

SMG1 ATM

7.97e-0461382SM01343
DomainARM-like

SMG1 DOCK8 RANBP6 CLASP2 XPO5 ASPM HEATR3 IPO11

9.05e-042701388IPR011989
DomainTHIOL_PROTEASE_CYS

CAPN3 CAPN8 CTSS

9.06e-04261383PS00139
DomainTHIOL_PROTEASE_ASN

CAPN3 CAPN8 CTSS

1.01e-03271383PS00640
DomainTHIOL_PROTEASE_HIS

CAPN3 CAPN8 CTSS

1.01e-03271383PS00639
DomainCAMSAP_CH

ASPM VAV2

1.11e-0371382PF11971
DomainCAMSAP_CH

ASPM VAV2

1.11e-0371382IPR022613
Domain-

ABCC1 ABCA1 ABCA3 MCM3 CHD8 GUF1 RAB33A ABCA6 CHD6 DDX39A DNAH5 DNAH8 SNRNP200 DNAH11

1.26e-03746138143.40.50.300
DomainPH

DOCK11 SH2B2 PLEKHG1 ARHGEF4 PLEKHH2 PREX1 VAV2

1.58e-032291387PF00169
DomainNa_channel_asu

SCN11A SCN5A

2.35e-03101382IPR001696
DomainNa_trans_assoc

SCN11A SCN5A

2.35e-03101382IPR010526
DomainNa_trans_assoc

SCN11A SCN5A

2.35e-03101382PF06512
DomainPribosyltran

PRPS1L1 PRPS1

2.85e-03111382PF00156
DomainIQ

MYO5B ADGB SCN5A ASPM

3.06e-03811384SM00015
Domaincalpain_III

CAPN3 CAPN8

3.41e-03121382SM00720
DomainC2_III

CAPN3 CAPN8

3.41e-03121382IPR033883
DomainCalpain_III

CAPN3 CAPN8

3.41e-03121382IPR022683
DomainPRTase-like

PRPS1L1 PRPS1

3.41e-03121382IPR029057
DomainPRibTrfase_dom

PRPS1L1 PRPS1

3.41e-03121382IPR000836
Domain-

PRPS1L1 PRPS1

3.41e-031213823.40.50.2020
DomainABC_transporter_CS

ABCC1 ABCA1 ABCA3

3.67e-03421383IPR017871
DomainCalpain_III

CAPN3 CAPN8

4.01e-03131382PF01067
DomainCalpain_domain_III

CAPN3 CAPN8

4.01e-03131382IPR022682
DomainIQ_motif_EF-hand-BS

MYO5B ADGB SCN5A ASPM

4.46e-03901384IPR000048
DomainPH

DOCK11 SH2B2 PLEKHG1 ARHGEF4 PLEKHH2 PREX1 VAV2

4.65e-032781387SM00233
DomainCalpain_cysteine_protease

CAPN3 CAPN8

4.65e-03141382IPR022684
DomainPH_DOMAIN

DOCK11 SH2B2 PLEKHG1 ARHGEF4 PLEKHH2 PREX1 VAV2

4.74e-032791387PS50003
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

RNGTT CCT3 DOCK11 HSPBAP1 UBR4 ZZEF1 BIRC6 PARP4 BTD PITPNM3 CHD6 ATM TAS2R31 CFAP44 SNRNP200 HEATR3

6.97e-087361431629676528
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

UNC13B POLE PIEZO1 UBR4 DYRK1A CHD8 CLASP2 ZZEF1 PRAG1 BIRC6 SH2B2 PLEKHG1 PIK3CD FANCI SCN5A KCNQ2 ARHGEF4 PLEC PREX1

1.51e-0711051431935748872
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

SMG1 ANKFY1 CHD8 BIRC6 XPO5 CHD6 ARHGEF4 PREX1 SNRNP200

4.26e-07225143912168954
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

SMG1 ABCC1 AMFR CCT3 UBR4 BAG5 RANBP6 MCM3 YIF1B XPO5 COG1 FANCI HSD17B10 ATM TRMT1L SNRNP200 HEATR3 SAMD4A IPO11 PRPS1

1.96e-0614401432030833792
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

SMG1 SCN11A CCT3 MYO5B UBR4 SPG11 TKTL1 PRPS1L1 OR13D1 COG1 ASPM CHD6 ATM ARHGEF4 PLEC EIF4G3 DDX39A DNAH8 PREX1 PRPS1

2.00e-0614421432035575683
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

ANKFY1 CCT3 UBR4 BAG5 RANBP6 MCM3 DYNLT3 ZZEF1 BIRC6 XPO5 FANCI ARIH2 TIMELESS HSD17B10 PLEC FH DDX39A SNRNP200 IPO11 PRPS1

2.29e-0614551432022863883
Pubmed

Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.

DNAH5 DNAH8 DNAH11

2.35e-06714339256245
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH5 DNAH8 DNAH11

2.35e-067143331178125
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

ANKFY1 CCT3 UBR4 BAG5 MCM3 CLASP2 XPO5 FANCI HSD17B10 TRMT1L PLEC SNRNP200 IPO11

2.56e-066381431333239621
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

RNGTT UBR4 BAG5 CHD8 XPO5 PRKAR2B CHD6 HSD17B10 DDX39A

2.76e-06282143923667531
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

ABCA1 DOCK11 PRAMEF22 CAPN3 BIRC6 SPATS2L FANCI ASPM CHD6 PLEC

2.83e-063631431014691545
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

CCT3 DOCK8 POLE CHD8 PARP4 XPO5 FANCI ATM TRMT1L PLEC DDX39A SNRNP200

5.61e-065821431220467437
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

CCT3 ANXA4 UBR4 MCM3 CHD8 ZZEF1 GUF1 HSD17B10 PLEC FH DDX39A SNRNP200 VAV2 PRPS1

6.60e-068071431430575818
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

CCT3 MYO5B DOCK8 DYRK1A CLASP2 HDHD2 GRM5 GPD1L SFXN3 KCNQ2 PRKAR2B ARHGEF4 PLEC FH EIF4G3 SNRNP200 MAPK8IP2 DNAH11 PRPS1

6.88e-0614311431937142655
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

HSD17B7 CCT3 POLE UBR4 MCM3 BIRC6 ARIH2 TIMELESS EIF4G3 DDX39A DNAH5 DNAH8 SNRNP200

7.39e-067041431329955894
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

CCT3 UBR4 MCM3 CHD8 XPO5 TRMT1L PLEC DDX39A SNRNP200

1.03e-05332143932786267
Pubmed

Combinatorial CRISPR screen identifies fitness effects of gene paralogues.

SMG1 RANBP6 DYNLT3 CLASP2 YIF1B ASPM DDX39A

1.27e-05186143733637726
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

DOCK4 PANK3 DOCK11 NTRK3 DYRK1A CLASP2 PRAG1 PLEKHG1 STOX2 ARHGEF4 PLEC EIF4G3 SAMD4A CCSER1

1.36e-058611431436931259
Pubmed

SMG1 heterozygosity exacerbates haematopoietic cancer development in Atm null mice by increasing persistent DNA damage and oxidative stress.

SMG1 ATM

1.68e-052143231565865
Pubmed

A novel conserved targeting motif found in ABCA transporters mediates trafficking to early post-Golgi compartments.

ABCA1 ABCA3

1.68e-052143221586796
Pubmed

hSMG-1 and ATM sequentially and independently regulate the G1 checkpoint during oxidative stress.

SMG1 ATM

1.68e-052143218332866
Pubmed

Increased Expression of the ABCA1 and ABCA3 Transporter Genes is Associated with Cisplatin Resistance in Breast Cancer Cells.

ABCA1 ABCA3

1.68e-052143238019257
Pubmed

Rare variants in dynein heavy chain genes in two individuals with situs inversus and developmental dyslexia: a case report.

DNAH5 DNAH11

1.68e-052143232357925
Pubmed

Specialized functions of Nav1.5 and Nav1.9 channels in electrogenesis of myenteric neurons in intact mouse ganglia.

SCN11A SCN5A

1.68e-052143224719102
Pubmed

Cardiac Na+ current regulation by pyridine nucleotides.

GPD1L SCN5A

1.68e-052143219745168
Pubmed

Expression of the lipid transporters ABCA3 and ABCA1 is diminished in human breast cancer tissue.

ABCA1 ABCA3

1.68e-052143219902402
Pubmed

Mutation in glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) decreases cardiac Na+ current and causes inherited arrhythmias.

GPD1L SCN5A

1.68e-052143217967977
Pubmed

Identification of carboxyl-terminal MCM3 phosphorylation sites using polyreactive phosphospecific antibodies.

MCM3 ATM

1.68e-052143217244605
Pubmed

Ciliary defects and genetics of primary ciliary dyskinesia.

DNAH5 DNAH11

1.68e-052143219410201
Pubmed

GPD1L links redox state to cardiac excitability by PKC-dependent phosphorylation of the sodium channel SCN5A.

GPD1L SCN5A

1.68e-052143219666841
Pubmed

Disease severity in a mouse model of ataxia telangiectasia is modulated by the DNA damage checkpoint gene Hus1.

HUS1 ATM

1.68e-052143222575700
Pubmed

Morphological, immunophenotypical and molecular features of hypermutation in colorectal carcinomas with mutations in DNA polymerase ε (POLE).

POLE NTRK3

1.68e-052143231479159
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

CCT3 POLE UBR4 CHD8 BIRC6 XPO5 FANCI ATM PLEC FH EIF4G3 SNRNP200

1.76e-056531431222586326
Pubmed

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.

ANKFY1 CCT3 UBR4 MCM3 PPHLN1 CLASP2 HSD17B10 PLEC FH SNRNP200 PRPS1

1.88e-055511431134728620
Pubmed

Molecular physiology of renal organic anion transporters.

ABCC1 ABCA1 SLCO3A1

1.89e-0513143316403838
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

DOCK4 AMFR HUS1 CNOT10 POLE UBR4 DYRK1A MCM3 CLASP2 XPO5 FANCI ASPM EIF4G3 PREX1 SNRNP200 SAMD4A IPO11

2.26e-0512841431717353931
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH5 DNAH8 DNAH11

2.40e-051414339373155
Pubmed

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.

DOCK4 DOCK11 DOCK8

2.40e-0514143312432077
Pubmed

CUL2LRR1 , TRAIP and p97 control CMG helicase disassembly in the mammalian cell cycle.

POLE MCM3 TIMELESS

2.99e-0515143333590678
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

NRIP1 CCT3 UBR4 MCM3 CHD8 GUF1 XPO5 PRKAR2B CHD6 HSD17B10 TRMT1L PLEC FH DDX39A SNRNP200 IPO11 PRPS1

3.14e-0513181431730463901
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

ANXA4 BAG5 RANBP6 CHD8 SPG11 CLASP2 GUF1 YIF1B XPO5 COG1 FANCI TIMELESS ATM FH IPO11

3.37e-0510611431533845483
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

SMG1 NRIP1 ANKFY1 CAPN3 PPHLN1 CLASP2 BIRC6 PARP4 PLEC VAV2

4.26e-054971431023414517
Pubmed

Class IA phosphoinositide 3-kinase β and δ regulate neutrophil oxidase activation in response to Aspergillus fumigatus hyphae.

PIK3CD PREX1 VAV2

4.44e-0517143321257963
Pubmed

Promoter regions of the human X-linked housekeeping genes PRPS1 and PRPS2 encoding phosphoribosylpyrophosphate synthetase subunit I and II isoforms.

PRPS1L1 PRPS1

5.02e-05314321314091
Pubmed

Targeting the Microtubule EB1-CLASP2 Complex Modulates NaV1.5 at Intercalated Discs.

CLASP2 SCN5A

5.02e-053143234092082
Pubmed

Mammalian TIMELESS is required for ATM-dependent CHK2 activation and G2/M checkpoint control.

TIMELESS ATM

5.02e-053143219996108
Pubmed

The ATP-dependent chromatin remodeling enzymes CHD6, CHD7, and CHD8 exhibit distinct nucleosome binding and remodeling activities.

CHD8 CHD6

5.02e-053143228533432
Pubmed

RIP140 triggers foam-cell formation by repressing ABCA1/G1 expression and cholesterol efflux via liver X receptor.

NRIP1 ABCA1

5.02e-053143225616132
Pubmed

Shared and divergent mental health characteristics of ADNP-, CHD8- and DYRK1A-related neurodevelopmental conditions.

DYRK1A CHD8

5.02e-053143238622540
Pubmed

Function of prokaryotic and eukaryotic ABC proteins in lipid transport.

ABCC1 ABCA1

5.02e-053143215749056
Pubmed

The chromatin remodeler CHD8 governs hematopoietic stem/progenitor survival by regulating ATM-mediated P53 protein stability.

CHD8 ATM

5.02e-053143234292326
Pubmed

The ATM-related kinase, hSMG-1, bridges genome and RNA surveillance pathways.

SMG1 ATM

5.02e-053143215279777
Pubmed

Examining the role of ABC lipid transporters in pulmonary lipid homeostasis and inflammation.

ABCA1 ABCA3

5.02e-053143228241820
Pubmed

Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo.

UNC13B HUS1 MYO5B FBXW12 PRAMEF22 BIRC6 FANCI ASPM

6.50e-05326143817015433
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

SMG1 NRIP1 ANKFY1 HUS1 POLE UBR4 PARP4 PITPNM3 CHD6 PREX1 DNAH11

7.06e-056381431131182584
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

UNC13B NRIP1 UBR4 DYRK1A DALRD3 GUF1 COG1 ARIH2 KCNQ2 CHD6 ATM PLEC EIF4G3 PREX1 SNRNP200 MAPK8IP2

8.22e-0512851431635914814
Pubmed

Quantitative targeted absolute proteomic analysis of transporters, receptors and junction proteins for validation of human cerebral microvascular endothelial cell line hCMEC/D3 as a human blood-brain barrier model.

ABCC1 ABCA3 ABCA6

8.57e-0521143323137377
Pubmed

Mutations in dynein genes in patients affected by isolated non-syndromic asthenozoospermia.

DNAH5 DNAH11

1.00e-044143218492703
Pubmed

mRNA expression profile of multidrug-resistant genes in acute lymphoblastic leukemia of children, a prognostic value for ABCA3 and ABCA2.

ABCC1 ABCA3

1.00e-044143224145140
Pubmed

The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells.

SMG1 ATM

1.00e-044143215175154
Pubmed

Receptor Tyrosine Kinase MET Interactome and Neurodevelopmental Disorder Partners at the Developing Synapse.

NTRK3 GRM5

1.00e-044143227086544
Pubmed

Rho GEFs and cancer: linking gene expression and metastatic dissemination.

PREX1 VAV2

1.00e-044143223033535
Pubmed

FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway.

FANCI ATM

1.00e-044143218931676
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

DOCK11 DOCK8 CNOT10 BAG5 CLASP2 BIRC6 PLEKHG1 SAMD4A IPO11

1.01e-04446143924255178
Pubmed

An abundance of X-linked genes expressed in spermatogonia.

PRAMEF22 TKTL1 TEX11 TDRD1

1.05e-0459143411279525
Pubmed

Stasimon/Tmem41b localizes to mitochondria-associated ER membranes and is essential for mouse embryonic development.

AMFR CCT3 ZZEF1 XPO5 FANCI

1.08e-04113143530352685
Pubmed

Charting the landscape of tandem BRCT domain-mediated protein interactions.

UNC13B AMFR RNGTT DYRK1A PPHLN1 CLASP2 DALRD3 ASPM TRMT1L EIF4G3 SNRNP200

1.09e-046701431122990118
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

DOCK4 ANKFY1 DOCK11 DOCK8 MCM3 PLEKHG1 FANCI HSD17B10 ARHGEF4 PLEC DDX39A PREX1 VAV2

1.11e-049161431332203420
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

AMFR CNOT10 XPO5 FANCI PRKAR2B TIMELESS HSD17B10 SNRNP200 HEATR3 IPO11

1.14e-045601431035241646
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

CCT3 ZZEF1 SCN5A PLEC CFAP44 DNAH8

1.29e-04187143626460568
Pubmed

Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family.

UNC13B RNGTT DOCK11 FBXW12 CNOT10 RANBP6 PRPS1L1 YIF1B XPO5 CERS3 HSD17B10 HEATR3 PRPS1

1.30e-049311431327432908
Pubmed

EB1-binding-myomegalin protein complex promotes centrosomal microtubules functions.

CLASP2 BIRC6 PRKAR2B PLEC

1.35e-0463143429162697
Pubmed

C16orf72/HAPSTR1 is a molecular rheostat in an integrated network of stress response pathways.

ANKFY1 CCT3 CLASP2 XPO5 FH

1.37e-04119143535776542
Pubmed

POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.

CCT3 MFSD4A GUF1 CHD6 PLEC DDX39A DNAH5

1.57e-04277143730745168
Pubmed

Characterization of functional domains in human Claspin.

POLE TIMELESS

1.67e-045143221478680
Pubmed

High prevalence of respiratory ciliary dysfunction in congenital heart disease patients with heterotaxy.

DNAH5 DNAH11

1.67e-045143222499950
Pubmed

Early development of electrical excitability in the mouse enteric nervous system.

SCN11A SCN5A

1.67e-045143222875929
Pubmed

Evolutionary analysis of a cluster of ATP-binding cassette (ABC) genes.

ABCA1 ABCA6

1.67e-045143212532264
Pubmed

ABCA3 inactivation in mice causes respiratory failure, loss of pulmonary surfactant, and depletion of lung phosphatidylglycerol.

ABCA1 ABCA3

1.67e-045143217142808
Pubmed

Role of DNA damage response pathways in preventing carcinogenesis caused by intrinsic replication stress.

HUS1 ATM

1.67e-045143223975433
Pubmed

Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin.

FANCI ATM

1.67e-045143215199141
Pubmed

ATR-mediated phosphorylation of FANCI regulates dormant origin firing in response to replication stress.

MCM3 FANCI

1.67e-045143225843623
Pubmed

DNAH11 Localization in the Proximal Region of Respiratory Cilia Defines Distinct Outer Dynein Arm Complexes.

DNAH5 DNAH11

1.67e-045143226909801
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ANKFY1 CCT3 DOCK11 UBR4 DYRK1A MCM3 CHD8 CLASP2 GRM5 STOX2 SFXN3 PRKAR2B MAPK8IP2

1.81e-049631431328671696
Pubmed

5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia.

SMG1 RANBP6 ATM

1.85e-0427143323027611
Pubmed

Deubiquitinating enzyme PSMD14 promotes tumor metastasis through stabilizing SNAIL in human esophageal squamous cell carcinoma.

DOCK4 CCT3 MCM3 XPO5 HSD17B10 DDX39A IPO11 PRPS1

1.96e-04383143829331416
Pubmed

VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.

AMFR CCT3 CNOT10 UBR4 FANCI ARIH2 PLEC

1.99e-04288143723383273
Pubmed

Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.

RNGTT CCT3 POLE XPO5 TRMT1L SNRNP200

2.49e-04211143617314511
Pubmed

P-Rex and Vav Rac-GEFs in platelets control leukocyte recruitment to sites of inflammation.

PREX1 VAV2

2.49e-046143225538043
Pubmed

Membrane Cholesterol Efflux Drives Tumor-Associated Macrophage Reprogramming and Tumor Progression.

ABCA1 PIK3CD

2.49e-046143230930171
Pubmed

Activation of the small GTPase Rac2 via the B cell receptor regulates B cell adhesion and immunological-synapse formation.

PIK3CD VAV2

2.49e-046143218191593
Pubmed

CFAP53 regulates mammalian cilia-type motility patterns through differential localization and recruitment of axonemal dynein components.

DNAH5 DNAH11

2.49e-046143233347437
Pubmed

Interaction of Ras with p110γ is required for thymic β-selection in the mouse.

PIK3CD VAV2

2.49e-046143221930962
Pubmed

Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases.

MCM3 ATM

2.49e-046143215210935
Pubmed

Colocalization and coassembly of two human brain M-type potassium channel subunits that are mutated in epilepsy.

KCNQ2 PRKAR2B

2.49e-046143210781098
Pubmed

Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.

ANKFY1 ANXA4 UBR4 GPD1L DDX39A SNRNP200 VAV2

2.76e-04304143732235678
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

CCT3 UBR4 BAG5 MCM3 CLASP2 XPO5 FANCI PRKAR2B HSD17B10 TRMT1L PLEC EIF4G3 SNRNP200 PRPS1

2.91e-0411491431435446349
Pubmed

Global Interactome Mapping of Mitochondrial Intermembrane Space Proteases Identifies a Novel Function for HTRA2.

ABCA1 UBR4 MCM3 ZZEF1 BIRC6 GUF1 SFXN3 EIF4G3 HEATR3

2.95e-04515143931617661
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

CCT3 POLE ANXA4 UBR4 MCM3 PPHLN1 CHD8 XPO5 FANCI ARIH2 ATM TRMT1L PLEC

2.97e-0410141431332416067
Pubmed

Primary Ciliary Dyskinesia

DNAH5 DNAH8 DNAH11

3.09e-0432143320301301
Cytoband3p22.3

CNOT10 CLASP2 GPD1L

1.22e-043114233p22.3
CytobandEnsembl 112 genes in cytogenetic band chr3p22

SCN11A CNOT10 CLASP2 GPD1L SCN5A

2.82e-041841425chr3p22
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

PLEKHG1 ARHGEF4 ARHGEF37 PREX1 VAV2

1.82e-0566895722
GeneFamilyATP binding cassette subfamily A

ABCA1 ABCA3 ABCA6

4.04e-0514893805
GeneFamilyC2 domain containing|Calpains

CAPN3 CAPN8 ADGB

5.03e-0515893975
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

DOCK11 SH2B2 PLEKHG1 ARHGEF4 PLEKHH2 PREX1 VAV2

7.04e-05206897682
GeneFamilyDyneins, axonemal

DNAH5 DNAH8 DNAH11

7.46e-0517893536
GeneFamilySodium voltage-gated channel alpha subunits

SCN11A SCN5A

8.43e-0498921203
CoexpressionGSE26495_NAIVE_VS_PD1LOW_CD8_TCELL_DN

ANXA4 PIEZO1 SLCO3A1 TMEM273 SPATS2L BTD SFXN3 EIF4G3 PREX1

1.28e-062001399M4659
CoexpressionGSE1460_INTRATHYMIC_T_PROGENITOR_VS_THYMIC_STROMAL_CELL_UP

HSD17B7 HSPBAP1 BAG5 CAPN3 GPD1L TIMELESS FH SNRNP200

1.11e-051981398M3449
CoexpressionGSE9037_CTRL_VS_LPS_1H_STIM_BMDM_DN

NRIP1 HSD17B7 HSPBAP1 DYRK1A TKTL1 ARIH2 PLEKHH2 MCEMP1

1.20e-052001398M5801
CoexpressionAtlasDevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_1000

DOCK4 SMG1 NRIP1 ANKFY1 PANK3 CCT3 DOCK11 MCM3 CHD8 TKTL1 TEX11 BIRC6 CSNK1G1 DMRTA2 GREB1 ATM DNAH8

7.27e-0677613317gudmap_developingGonad_e14.5_ ovary_1000
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_1000

DOCK4 SMG1 NRIP1 ANKFY1 PANK3 DOCK11 CHD8 TKTL1 TEX11 BIRC6 ENO4 ADGRG2 ASPM DMRTA2 GREB1 PLEC DNAH8

9.97e-0679513317gudmap_developingGonad_e16.5_ovary_1000
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 DOCK8 SLCO3A1 GRM5 PARP4 STOX2 PLEKHH2 UNC5D DNAH11

6.61e-0918214095e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 SLCO3A1 GRM5 PARP4 STOX2 PLEKHH2 UNC5D DNAH11

8.99e-081761408327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 DOCK8 SLCO3A1 GRM5 STOX2 PLEKHH2 UNC5D DNAH11

1.38e-0718614085c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCellCOVID-19-Epithelial_cells|COVID-19 / group, cell type (main and fine annotations)

UNC13B ABCA3 MYO5B CAPN8 STOX2 DNAH5 DNAH11 CCSER1

1.49e-071881408c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 SLCO3A1 GRM5 PARP4 STOX2 PLEKHH2 UNC5D DNAH11

1.49e-07188140863a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 SLCO3A1 GRM5 PARP4 STOX2 PLEKHH2 UNC5D DNAH11

1.56e-071891408904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GRM5 TDRD1 ADGB CFAP44 DNAH5 WDR49 DNAH11

1.10e-06169140714aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellMild/Remission-B_memory-6|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

AMFR ANXA4 SH2B2 TMEM273 RAB33A DNAH8 PREX1

1.50e-0617714078f2ce5ffc94ca90412cb6899629f322dc778215c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO5B DOCK11 DOCK8 STOX2 SPATS2L UNC5D SAMD4A

2.08e-061861407f28d72b47624b69a580b4429e2be560a26898591
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYO5B DOCK11 DOCK8 STOX2 SPATS2L UNC5D SAMD4A

2.16e-0618714079d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CAPN8 STOX2 EMP1 PLEKHH2 DNAH5 SAMD4A CCSER1

2.40e-0619014073fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 SLCO3A1 PARP4 STOX2 PLEKHH2 DNAH5 UNC5D

2.48e-061911407d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PRAG1 PARP4 STOX2 PLEKHH2 DNAH5 SAMD4A CCSER1

2.75e-061941407e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ANXA4 SLCO3A1 CAPN8 PLEKHG1 PLEKHH2 DNAH5 SAMD4A

2.85e-061951407938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCellControl-cDC-|Control / Disease condition and Cell class

CCT3 PPHLN1 TMEM273 SPATS2L YIF1B EMP1 CCSER1

2.85e-061951407a2b4d9473eff73f088b247ce43e66f013622471e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ANXA4 SLCO3A1 CAPN8 PLEKHG1 PLEKHH2 DNAH5 SAMD4A

2.85e-061951407d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCellControl-cDC|Control / Disease condition and Cell class

CCT3 PPHLN1 TMEM273 SPATS2L YIF1B EMP1 CCSER1

2.85e-061951407b96acdd22dd3885af69328f170ea871a0d570034
ToppCellbackground-Endothelial_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

DOCK4 SLCO3A1 PRAG1 PLEKHG1 RASIP1 STOX2 CCSER1

2.95e-061961407e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCellMonocytes-NUPR1+_Monocytes|Monocytes / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

DOCK4 ANXA4 PPHLN1 SPATS2L PLEC EMP1 SNRNP200

3.05e-0619714078a058c9d9285acd7cf2fb8e34f7602a86b5d6c89
ToppCellCOVID-19-lung|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK4 ABCA1 ABCA3 DOCK11 DOCK8 CAPN8 CTSS

3.26e-061991407155b03b859157013e9142e9248551369127d9204
ToppCellPBMC-Mild-cDC_2|Mild / Compartment, Disease Groups and Clusters

RNF152 TKTL1 TDRD1 PLEKHG1 STOX2 PLEKHH2

4.40e-061351406cb9d834f8301cf53f20e09c3f4cb6a148690196a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 GRM5 PARP4 STOX2 UNC5D DNAH11

9.04e-061531406d6526d17826470534b766df144c74e73eb83fdad
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC9C2 ADGB CFAP44 DNAH5 WDR49 DNAH11

9.73e-0615514065f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC9C2 ADGB CFAP44 DNAH5 WDR49 DNAH11

9.73e-0615514060944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCellMild/Remission-B_memory-6|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

AMFR ANXA4 TMEM273 RAB33A DNAH8 PREX1

1.44e-05166140603e1a369d8a83b814def07e29cabb023226b4828
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

UNC13B DOCK4 ABCA1 PLEKHG1 STOX2 SAMD4A

1.64e-051701406e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCellControl-Epithelial_cells-AT1|Control / group, cell type (main and fine annotations)

UNC13B DOCK4 ABCA1 MYO5B STOX2 SAMD4A

1.88e-051741406548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 DOCK11 DOCK8 CERS3 EIF4G3 CTSS

1.94e-051751406cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABCC1 RNGTT SLCO3A1 PITPNM3 ATM SAMD4A

1.94e-051751406711ace94fa9a763c6ae48171a690953f25deebe4
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 SLCO3A1 STOX2 PLEKHH2 UNC5D DNAH11

1.94e-051751406284fdc7a9d303636a637041846850d19d114861a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 DOCK8 SLCO3A1 GRM5 STOX2 UNC5D

2.34e-0518114066956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCellCOVID-19-Epithelial_cells-ECM-high_epithelial|COVID-19 / group, cell type (main and fine annotations)

UNC13B ABCA3 ZPLD1 CAPN8 STOX2 ARHGEF4

2.49e-051831406dc1d380bf7564f290256cb7108063d1bd2da732b
ToppCellB_cells-ISG-high_B_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

AMFR SH2B2 PLEKHG1 DNAH8 SAMD4A CCSER1

2.49e-051831406dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TEX11 CAPN8 KCNQ2 DNAH5 UNC5D DNAH11

2.57e-0518414062cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TEX11 CAPN8 KCNQ2 DNAH5 UNC5D DNAH11

2.57e-051841406ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TEX11 CAPN8 KCNQ2 DNAH5 UNC5D DNAH11

2.57e-0518414062b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 SLCO3A1 PARP4 STOX2 UNC5D DNAH11

2.57e-051841406da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCellCOPD-Myeloid-Macrophage_Alveolar|World / Disease state, Lineage and Cell class

AMFR DOCK8 TIMELESS WDR49 MCEMP1 CCSER1

2.57e-0518414067fd0b227c3750ffb80e41e92c60fcce46656be14
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

MFSD4A CAPN8 GPD1L PLEKHG1 KCNQ2 DNAH5

2.57e-051841406102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

UNC13B MFSD4A CAPN8 STOX2 DNAH5 CCSER1

2.65e-051851406cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellControl-Myeloid-Macrophage_Alveolar|World / Disease state, Lineage and Cell class

NRIP1 DOCK11 DOCK8 PRAG1 SPATS2L MCEMP1

2.65e-05185140685cb81759589a26d83676cffbf2bc37399683c10
ToppCellpdx-Tumor_cells-T0|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ABCA1 TSPAN32 SPATS2L GREB1 VAV2 SAMD4A

2.65e-0518514061d874608aa2062024323512f68889219471b2f00
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RNF152 MFSD4A RASIP1 F11R EMP1 PREX1

2.65e-051851406602536a3308a848f106adcb0a83530997440c8f4
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

UNC13B ABCA3 MYO5B CAPN8 STOX2 DNAH5

2.90e-051881406707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYO5B DOCK11 STOX2 SPATS2L UNC5D SAMD4A

2.99e-0518914063b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

UNC13B MYO5B PLEKHG1 STOX2 WDR49 CCSER1

2.99e-0518914067659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pdgfa_(Mural.Rgs5Acta2.Pdgfa)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

CYB5RL DOCK8 POLE KLHL31 DNAH8

3.04e-0511414052cc5d2da5573650c5232a01e2d2128082c4bffcb
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pdgfa_(Mural.Rgs5Acta2.Pdgfa)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

CYB5RL DOCK8 POLE KLHL31 DNAH8

3.04e-051141405fceb7cc590a47380145fc0d854c9f2350dbb0a59
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYO5B DOCK8 STOX2 SPATS2L UNC5D SAMD4A

3.08e-051901406989d4eefd22d66ecb857836f8fdbcf41e3047f84
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Excitatory_Neuron.Slc17a6.Tcf7l2_(Substantia_Innominata_(SI))|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

NMUR2 CAPN8 PLAC8L1 DMRTA2

3.12e-05571404eab63d89e2100bb94fb026f700c2f82d657f92c1
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Excitatory_Neuron.Slc17a6.Tcf7l2_(Substantia_Innominata_(SI))-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

NMUR2 CAPN8 PLAC8L1 DMRTA2

3.12e-055714042dc04513910af16d2cd84b3ae5b8d4c831124c68
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CAPN8 EMP1 PLEKHH2 DNAH5 SAMD4A CCSER1

3.17e-0519114065a67ff17fb4b9eff641176dff07830c9cd73754e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CAPN8 EMP1 PLEKHH2 DNAH5 SAMD4A CCSER1

3.17e-05191140655ab2854a02cdcfc395e49870ccb7290b5e5471d
ToppCellControl-Myeloid-Macrophage_Alveolar|Myeloid / Disease state, Lineage and Cell class

DOCK11 DOCK8 PRAG1 SPATS2L MCEMP1 SAMD4A

3.17e-051911406a7bb8aba9c59c037d995a77928cc7b4d5cbb82b9
ToppCellRV-08._Macrophage|World / Chamber and Cluster_Paper

DOCK11 DOCK8 PIK3CD ASPM PREX1 CTSS

3.26e-051921406a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCell3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RNF152 PLEKHG1 RASIP1 EMP1 PREX1 IPO11

3.26e-0519214061f35efb0765e05f7f9c881849953bef3965be25a
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

UNC13B ABCA3 MYO5B CAPN8 STOX2 DNAH5

3.26e-051921406efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

UNC13B MYO5B PLEKHG1 STOX2 WDR49 CCSER1

3.26e-051921406b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 GRM5 PARP4 PLEKHH2 UNC5D DNAH11

3.36e-051931406ffa1932da2979d7b63dbac32eb5788346a3f5b2a
ToppCellRV-08._Macrophage|RV / Chamber and Cluster_Paper

DOCK11 DOCK8 PIK3CD ASPM PREX1 CTSS

3.36e-05193140612bf98a280f87e4d8f0c6887dfc855da72e47ac1
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PRAG1 CAPN8 PLEKHH2 DNAH5 SAMD4A CCSER1

3.36e-051931406f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLCO3A1 CAPN8 EMP1 PLEKHH2 DNAH5 SAMD4A

3.36e-051931406263d185af6ed80e639f864e4966268e0862c61dc
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLCO3A1 CAPN8 EMP1 PLEKHH2 DNAH5 SAMD4A

3.36e-05193140680e058c224749b5fe0ba3e944b48317c2371cb63
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLCO3A1 CAPN8 EMP1 PLEKHH2 DNAH5 SAMD4A

3.36e-051931406b991fbbb4618401624f0b3045f0e81a606d3a763
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PRAG1 CAPN8 PLEKHH2 DNAH5 SAMD4A CCSER1

3.36e-05193140642df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCell3'_v3-blood-Lymphocytic_NK-Cycling_NK|blood / Manually curated celltypes from each tissue

POLE MCM3 FANCI ASPM TIMELESS DDX39A

3.46e-051941406bf9734abaad603ade2a6a6940918aaf1e1c4e2cd
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

UNC13B MYO5B PLEKHG1 DNAH5 WDR49 CCSER1

3.46e-051941406f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

UNC13B ABCA3 MYO5B CAPN8 STOX2 DNAH5

3.56e-0519514069406866f99555198a9be311fbd65751b70f35446
ToppCell(1)_Control_(PBS)-(1)_VE-Cad+_vascular_cells|World / Stress and Cell class

ABCA1 PIEZO1 PLEKHG1 RASIP1 F11R IPO11

3.56e-0519514066b5d3ecec0c00ebfc889dc6235390ff53b5c0b6a
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC9C2 ADGB CFAP44 DNAH5 WDR49 DNAH11

3.76e-05197140674a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RNF152 MYO5B MFSD4A PRKAR2B PLEC CFAP44

3.76e-0519714065c4cee914baf7cb43e9cb99cc9e3ae823856dc15
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

UNC13B DOCK4 DYRK1A SLCO3A1 STOX2 CCSER1

3.87e-0519814061996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellBronchial-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

UNC13B ABCA3 MYO5B CAPN8 STOX2 CCSER1

3.98e-0519914065f7da3eab58ace6cddb3179a415cd839d5767958
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

UNC13B ABCA3 MYO5B CAPN8 STOX2 CCSER1

3.98e-0519914065cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_CTL|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK11 DOCK8 TSPAN32 PIK3CD ATM PREX1

3.98e-051991406eb188b0b457136b6ee485d3b3052baa30d9c0002
ToppCellmyeloid-pro-cDC|myeloid / Lineage and Cell class

CCT3 MCM3 SPATS2L ASPM FH DDX39A

4.10e-0520014064aa2308eeb94e0bdff4e02eb9e45ba8837ae14bf
ToppCellControl-B_memory-6|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

RNF152 ANXA4 TMEM273 DNAH8 PREX1

4.54e-0512414053e987915026f503e8d072a837b6e7a34252e5c63
ToppCellControl-B_memory-6|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

RNF152 ANXA4 TMEM273 DNAH8 PREX1

7.05e-05136140594f23bef50c0beb54ed39b1a4b340f7aec4e75cd
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 PARP4 STOX2 PLEKHH2 UNC5D

7.30e-0513714050aa4e14b32da0cda677cc0ed6ae470f6ecd77bea
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABCA3 DOCK11 TDRD1 CSNK1G1 SLC30A10

8.93e-0514314058f897278f9ccc82ae35e4f30c5f930b2a3eb509d
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

BAG5 PRAG1 FANCI EIF4G3

1.02e-04771404ebb1a537751739232820a60f88911877fc683855
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGB ENO4 CFAP44 DNAH5 DNAH11

1.27e-0415414059ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGB ENO4 CFAP44 DNAH5 DNAH11

1.27e-04154140558072ce422d09f2de602580325eaac6c4ec6c136
ToppCellGlobus_pallidus-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Klk6_(Klk6)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

GNG8 TEX11 CERS3 ARHGEF37

1.30e-048214048d4b3339d34ee23060c85fb4e2e42bfe9579c738
ToppCellGlobus_pallidus-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Klk6_(Klk6)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

GNG8 TEX11 CERS3 ARHGEF37

1.30e-048214040c07ac1e7eb64bca6b09979e204d4b86338b0e40
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13B KLHL31 PLEKHH2 DNAH5 CCSER1

1.43e-041581405f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13B KLHL31 PLEKHH2 DNAH5 CCSER1

1.43e-0415814058c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCellPND07-Endothelial-Endothelial_lymphatic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN11A MFSD4A F11R SCN5A IPO11

1.56e-041611405133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN11A MFSD4A F11R SCN5A IPO11

1.56e-0416114059466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN11A MFSD4A F11R SCN5A IPO11

1.56e-041611405cb177ca10d848d0e25399ab5ebfcde1071fb94c2
ToppCellE18.5-samps-Myeloid-Macrophage-macrophage_-_intermediate_-_unactivated|E18.5-samps / Age Group, Lineage, Cell class and subclass

TSPAN32 TMEM273 PIK3CD CTSS MCEMP1

1.60e-04162140560d3fe1f5cec4285b8774ff078ebcc6bfaec26ed
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYB5RL DOCK11 DOCK8 PIK3CD DNAH8

1.60e-04162140558fe827198c172eeaa26273b0fad7991a718b0bf
ToppCellE18.5-samps-Myeloid|E18.5-samps / Age Group, Lineage, Cell class and subclass

TSPAN32 TMEM273 PIK3CD CTSS MCEMP1

1.60e-04162140518e4a807e25f754a69e9eaaddfde40f8de9b8512
ToppCellE18.5-samps-Myeloid-Macrophage|E18.5-samps / Age Group, Lineage, Cell class and subclass

TSPAN32 TMEM273 PIK3CD CTSS MCEMP1

1.60e-0416214050970e4eda60e3f015335e2726e6d565fb2f43372
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL31 CSNK1G1 ASPM VAV2 MCEMP1

1.60e-04162140593bd29c52846c3156b8b0d2e39c552373efdfe93
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Adult / Lineage, Cell type, age group and donor

ABCA3 CAPN8 GPD1L PITPNM3 DNAH5

1.65e-041631405e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCellfacs-Lung-EPCAM-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYB5RL HSD17B7 HUS1 GUF1 BTD

1.70e-0416414051d0d88132baaa3154c3e6e4ef0aff795afab08a2
ToppCellfacs-Lung-EPCAM-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYB5RL HSD17B7 HUS1 GUF1 BTD

1.70e-041641405bd2e10b015d5e6a338675500ec5d81dc39583b3e
ToppCellPND01-03-samps-Myeloid-Macrophage|PND01-03-samps / Age Group, Lineage, Cell class and subclass

TSPAN32 TMEM273 PRKAR2B CTSS MCEMP1

1.70e-04164140549733a9d3d95f05056b5b01916060ff20a8de3cf
ToppCellfacs-Large_Intestine-Proximal-24m-Epithelial-Enterocyte_(Proximal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF152 MYO5B EMP1 SLC30A10 CTSS

1.75e-041651405ce79d217df88035457cd58f679e72dd98722ae22
Diseasecognitive function measurement

ANKFY1 FBXW12 CNOT10 NTRK3 PIEZO1 BAG5 BIRC6 CAPN8 PLEKHG1 EDEM3 STOX2 SPATS2L EMP1 DNAH5 PREX1 SLC30A10 CALN1 CCSER1

9.81e-05143413518EFO_0008354
DiseaseKartagener syndrome (is_implicated_in)

DNAH5 DNAH11

1.24e-0441352DOID:0050144 (is_implicated_in)
DiseaseBronchiectasis

PIK3CD DNAH5 DNAH11

1.35e-04221353C0006267
Diseasehereditary spastic paraplegia 76 (implicated_via_orthology)

CAPN3 CAPN8

2.06e-0451352DOID:0110821 (implicated_via_orthology)
Diseasecolorectal cancer (is_implicated_in)

POLE NTRK3 XPO5 PIK3CD ATM

2.42e-041211355DOID:9256 (is_implicated_in)
Diseasecerebrospinal fluid biomarker measurement, monocyte chemotactic protein 1 measurement

EDEM3 UNC5D

3.08e-0461352EFO_0006794, EFO_0010596
Diseaseintellectual disability (implicated_via_orthology)

UBR4 CAPN3 DYRK1A CAPN8

3.96e-04751354DOID:1059 (implicated_via_orthology)
Diseaseunipolar depression

AMFR RNF152 RNGTT PANK3 BAG5 GRM5 OR51E2 ENO4 CHD6 EMP1 ARHGEF37 FH EIF4G3 SNRNP200 CCSER1

4.27e-04120613515EFO_0003761
DiseaseCHARGE syndrome (implicated_via_orthology)

CHD8 CHD6

4.30e-0471352DOID:0050834 (implicated_via_orthology)
DiseaseBrugada syndrome

GPD1L SCN5A

5.71e-0481352cv:C1142166
Diseasefemale breast cancer (is_implicated_in)

FANCI ATM

5.71e-0481352DOID:0050671 (is_implicated_in)
Diseaseendometrial cancer (is_implicated_in)

POLE PIK3CD ATM

5.99e-04361353DOID:1380 (is_implicated_in)
Diseaseautism spectrum disorder (implicated_via_orthology)

ABCA3 DYRK1A CHD8 CHD6 PREX1

6.88e-041521355DOID:0060041 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN11A SCN5A

9.13e-04101352DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN11A SCN5A

9.13e-04101352DOID:0080422 (implicated_via_orthology)
DiseaseThromboembolism

DOCK8 OR51E2 C11orf40

1.08e-03441353HP_0001907
DiseaseHbA1c measurement

ABCC1 CCT3 PIEZO1 SLCO3A1 DALRD3 SBK1 OR51E2 PLEKHH2 CTSS UNC5D

1.12e-0367513510EFO_0004541
DiseaseWeight Gain

HDHD2 IPO11 DNAH11 PRPS1

1.26e-031021354C0043094
DiseaseC-reactive protein measurement

DOCK4 ABCA1 ZPLD1 ANXA4 DYRK1A SPG11 GRM5 ZZEF1 PRAG1 SBK1 ABCA6 EMP1 EIF4G3 DNAH11

1.29e-03120613514EFO_0004458
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN11A SCN5A

1.33e-03121352DOID:0060170 (implicated_via_orthology)
DiseaseColorectal Carcinoma

UNC13B ABCC1 ABCA1 ABCA3 POLE ABCA6 DNAH8 SNRNP200 WDR49 PRPS1

1.50e-0370213510C0009402
DiseaseBrugada Syndrome 1

GPD1L SCN5A

1.57e-03131352C4551804
Diseasenon-alcoholic fatty liver disease, type 2 diabetes mellitus

RNGTT SLC9C2 DNAH8 VAV2

1.66e-031101354EFO_0003095, MONDO_0005148
DiseaseKartagener syndrome (implicated_via_orthology)

DNAH5 DNAH11

1.82e-03141352DOID:0050144 (implicated_via_orthology)
DiseaseAutosomal recessive limb-girdle muscular dystrophy

CAPN3 PLEC

1.82e-03141352cv:C2931907
Diseaseapolipoprotein A 1 measurement

OR5D16 AMFR ABCA1 MYO5B SPG11 GRM5 OR13D1 ABCA6 SLC30A10 CTSS CCSER1

1.84e-0384813511EFO_0004614
DiseasePR interval

DOCK4 PPHLN1 PLPP7 PRPS1L1 SCN5A CHD6 PLEC DNAH11

2.05e-034951358EFO_0004462
Diseaseuterine fibroid

DYNLT3 TEX11 GREB1 ATM HEATR3

2.27e-031991355EFO_0000731
Diseaselow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

CAPN3 SPG11 ABCA6 DMRTA2 CALN1

2.32e-032001355EFO_0004611, EFO_0020945
DiseaseMalignant lymphoma, lymphocytic, intermediate differentiation, diffuse

PIK3CD ATM

2.39e-03161352C0334634
DiseaseBenign neoplasm of stomach

POLE ATM

2.70e-03171352C0153943
DiseaseNeoplasm of uncertain or unknown behavior of stomach

POLE ATM

2.70e-03171352C0496905
DiseaseCarcinoma in situ of stomach

POLE ATM

2.70e-03171352C0154060
Diseasemonocyte count

NRIP1 HSD17B7 RNGTT CCT3 DOCK8 PIEZO1 CAPN3 TSPAN32 TDRD1 C11orf40 PIK3CD CSNK1G1 ATM PREX1

2.96e-03132013514EFO_0005091
Diseaseobsolete_red blood cell distribution width

ABCC1 NRIP1 CCT3 DOCK8 PIEZO1 TSPAN32 BIRC6 PLEKHG1 ABCA6 COG1 FANCI EIF4G3 SLC30A10 HEATR3

3.55e-03134713514EFO_0005192
Diseasesusceptibility to chronic sinus infection measurement

SLCO3A1 RANBP6 ADGRG2

3.78e-03681353EFO_0008419
Diseasetriglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement

ABCA1 CAPN3 SPG11 ABCA6 CALN1

3.83e-032251355EFO_0008317, EFO_0020947
Diseaselung non-small cell carcinoma (is_implicated_in)

POLE XPO5 ATM FH

3.88e-031391354DOID:3908 (is_implicated_in)
DiseaseBladder Neoplasm

AMFR ANKFY1 CHD6 ATM

3.98e-031401354C0005695
DiseaseMalignant neoplasm of urinary bladder

AMFR ANKFY1 CHD6 ATM

4.08e-031411354C0005684
DiseaseStomach Carcinoma

POLE ATM

4.12e-03211352C0699791
DiseaseEndometrial Carcinoma

NRIP1 POLE FH

4.44e-03721353C0476089
Diseasegamma-glutamylglutamine measurement

ABCC1 UNC5D

4.52e-03221352EFO_0021138
DiseaseDown syndrome (is_marker_for)

DYRK1A CTSS

4.52e-03221352DOID:14250 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
TRFQMCVAGIKLQAR

TDRD1

846

Q9BXT4
KVLIFSQMVRCLDIL

CHD8

1151

Q9HCK8
ISKERVQRCAMLQFS

BIRC6

1311

Q9NR09
INFVMCEVNKARGVL

BAG5

186

Q9UL15
SCRFTEQSLLIMKAI

ADGB

786

Q8N7X0
MCTFVTLQRDLAKQV

ARHGEF37

421

A1IGU5
LVMCHTRELAFQISK

DDX39A

116

O00148
IFVKSVQRCMALAQL

DDX39A

291

O00148
FTICMAFLVLSLAKS

HTR3B

306

O95264
RTISRFMECVNLNKL

ABCA1

496

O95477
QTLLFVFVLRCMELK

ABCA6

1206

Q8N139
TMNACAVIAALERVK

ADGRG2

196

Q8IZP9
FFEACRLLQKMIDIS

ARHGEF4

401

Q9NR80
FMARVRLQLKIILCF

DNAH11

2971

Q96DT5
LLIAASFMTLLFCVK

ABCA3

316

Q99758
VCMQFVRKENLLSLA

ARIH2

141

O95376
VACMIRLETLFKLFS

CAPN8

666

A6NHC0
FRLMLQDCTAVKTLL

CCSER1

621

Q9C0I3
LTRKFAQQMCTALLF

DYRK1A

261

Q13627
SFEDALLAIVKCMRN

ANXA4

231

P09525
VRKSLICAFAMAFII

CALN1

231

Q9BXU9
CAKCTLIAERQRVMA

DMRTA2

96

Q96SC8
QIKALRSEFCNLLEM

CFAP44

951

Q96MT7
VFSMNLQLRQTVCRK

CST9

91

Q5W186
RAAVTIQKAFCRMVT

ASPM

2816

Q8IZT6
TEFFRKLSMAVNLLC

RASIP1

826

Q5U651
VESIFMCLACRLKAQ

RAB33A

191

Q14088
VRQVIKLACTDMFVV

OR4N4C

181

A0A096LPK9
LCEARRAVQKNMIFI

GUF1

491

Q8N442
VAISQKLCAMLVVVL

OR5D16

136

Q8NGK9
KGVMSLVNVRNCIRF

ANKFY1

156

Q9P2R3
CLILVLRKAMFANQL

FANCI

516

Q9NVI1
LKTVQAFMILSIIFC

EMP1

61

P54849
QIHTLVKMCSDFLIR

KLHL31

151

Q9H511
RFMSACAQLVIAFIL

GRM5

686

P41594
RFCNDAMKVAFLISL

LDOC1

81

O95751
VNKMLFVLVLVFAIC

NMUR2

266

Q9GZQ4
NRTGFLICAFLVEKM

RNGTT

131

O60942
LCRFNRFSVMKKQIV

GREB1

1756

Q4ZG55
FCRDVKVLASVMALA

MFSD4A

101

Q8N468
FACVLLVVLFVMINK

NTRK3

441

Q16288
EMIAFARIFCKGQVS

GPD1L

236

Q8N335
MAACRALKAVLVDLS

HDHD2

1

Q9H0R4
VTFERFIVQCMNLIK

IPO11

311

Q9UI26
LCDRTFTLKTVLMIA

CSNK1G1

131

Q9HCP0
IALIQRGQCMFAEKA

EDEM3

706

Q9BZQ6
ILCAAMQKIATARKL

MAPK8IP2

701

Q13387
SVMCDNASIVLRVRK

FBXW12

436

Q6X9E4
LKVSIRAVCVMRFLV

KCNQ2

536

O43526
KQIRTRVLAMFKISC

OR51E2

296

Q9H255
IARLACASIKVNIMF

OR52E6

186

Q96RD3
VRQVIKLACTDMFVV

OR4N4

181

Q8N0Y3
MRVKLASCGFLENVI

DNAH8

1981

Q96JB1
TFVAFCIIAMDRLTK

CYB5RL

76

Q6IPT4
CAARLQAVASMVEKR

NRIP1

236

P48552
ALCSNTFRILKSMVV

POLE

1786

Q07864
LMAFTLQDLVCLKCR

POLE

2211

Q07864
ATLCALIQEKEFRTM

PARP4

1096

Q9UKK3
MAAACRSVKGLVAVI

HSD17B10

1

Q99714
RCVALESQLMKFRVQ

PLEKHH2

16

Q8IVE3
RMCAVNEKINRVVFV

PANK3

306

Q9H999
FRTVLIACNVKQMSK

MCM3

256

P25205
AITRMLVCALKTAEN

HSPBAP1

286

Q96EW2
FSVRMALVNCLKTLL

ATM

1036

Q13315
LNRCIFMKSIQDVRS

CERS3

326

Q8IU89
IRKMNTIQCRALFCL

HEATR3

456

Q7Z4Q2
MFRKFIQACSIALEL

DOCK11

1986

Q5JSL3
KDLIMCARILSNVFC

DOCK4

846

Q8N1I0
LASARNITIKIQFMC

DOCK8

576

Q8NF50
AKLHSVLFMARLCQS

COG1

606

Q8WTW3
RMKVSQAAAELLAFC

GNG8

26

Q9UK08
KVLIFSQMVRCLDIL

CHD6

801

Q8TD26
TACSLMKIANDIRFL

FH

331

P07954
FVVCIMSGARSKLAL

BTD

16

P43251
RNMSKAEAVCAALLA

HSD17B7

36

P56937
FSALSCKIVAFMAVL

GPR173

91

Q9NS66
LCIILSAFIMVKNAE

MCEMP1

96

Q8IX19
VSLAVAKACAMLLNK

ENO4

241

A6NNW6
RTMNCIVNVFAIAIV

DYNLT3

101

P51808
VKCLAMDVQAFERLL

PRKAR2B

371

P31323
MKRLVCVLLVCSSAV

CTSS

1

P25774
AVRTEMICKFLVQLS

DALRD3

476

Q5D0E6
VICSFLVALMQKNRR

CAPN3

476

P20807
VKRCVQQLGLALDFM

SBK1

151

Q52WX2
TFLRALMTAVCKAAI

EIF4G3

1461

O43432
LFLAMLSVVHCNSRK

PPHLN1

436

Q8NEY8
RIMDCVLLLFQRKVS

DNAH5

3321

Q8TE73
MGTKAQVERKLLCLF

F11R

1

Q9Y624
RKSISFIGCALQMVV

OR13D1

121

Q8NGV5
LVCALAILRSKIMTA

ABCC1

146

P33527
SFMLRLFLCKTNVIN

OR8G3P

161

P0DMU2
ACQLFVINMKEIVRT

TAS2R31

141

P59538
KALQTVISFLMLCAI

TAS2R33

226

P0DSN6
MKLNRQLIFCTLAAL

TRMT1L

256

Q7Z2T5
AKQGIFQVVISRICM

SFXN3

221

Q9BWM7
VLHNMSCISKRFTVI

RNF152

186

Q8N8N0
FSNIKIFLVSECALM

SLCO3A1

36

Q9UIG8
RFSCDIEQLKAQIML

SPATS2L

336

Q9NUQ6
VIVKNQLDMFLSFVC

NXPE3

541

Q969Y0
AFSICQVARELKMRT

PLAC8L1

146

A1L4L8
FTRISNMIAKLAKTC

HUS1

16

O60921
FTSRRCEVLKVMVQA

PRAMEF22

46

A3QJZ6
CKTSLQRVQLHIAMF

SMG1

3186

Q96Q15
INALDELCRLMKSFV

PREX1

1536

Q8TCU6
TKQAFDVTIMFLICL

SCN5A

1526

Q14524
LACNIALDAVKMVQF

CCT3

171

P49368
LIMINACKIASASRV

PRPS1L1

71

P21108
ASMRKKLCDIFAVLA

RANBP6

111

O60518
VLVNTACCVLMLVAK

AMFR

86

Q9UKV5
KVMATSGCAAIRFII

CLASP2

191

O75122
LLQVFAGKNCMDRVL

C11orf40

191

Q8WZ69
ASMEFAAICLRNALL

CNOT10

456

Q9H9A5
VVQFCRLHNMKLSIS

SPG11

1346

Q96JI7
LKMEALLFQLSVFCL

TIMELESS

736

Q9UNS1
GKTCRLLFMLVLTVA

SLC30A10

6

Q6XR72
CVAIFVFMIRTLRLK

YIF1B

256

Q5BJH7
VQAITMKINFCTVLF

ZPLD1

46

Q8TCW7
RVRVAKCQMLVTCFF

TSPAN32

6

Q96QS1
EILCLAISAMNSARK

STOX2

76

Q9P2F5
TDICLKNMAFIARKA

TRIM51

66

Q9BSJ1
AVMRLCFLKARKNTA

WDR49

371

Q8IV35
CALMEALVLISNQFK

XPO5

646

Q9HAV4
LMACALRKKATVFRQ

PIK3CD

216

O00329
ILIARKTCLLMAVAV

TEX11

676

Q8IYF3
VRKGFSLRNMSLCVV

SH2B2

131

O14492
MSLLCVRVKRAKFQG

UNC13B

1

O14795
IMVDRINLAQKAFCG

PLEC

4481

Q15149
CMAANIVAKRRSLSA

UNC5D

231

Q6UXZ4
QSLARLVAKCEDLFM

PRAG1

961

Q86YV5
AIFLRNLMQECFIKI

PITPNM3

821

Q9BZ71
FINAIRSAKQCMLAI

ZC2HC1B

86

Q5TFG8
KTICAEFAILRMLLQ

SNRNP200

1356

O75643
IVFLNKVMRGLSICT

VN1R5

121

Q7Z5H4
SMAARQLVIFLLDFC

ZZEF1

1031

O43149
LIMINACKIASASRV

PRPS1

71

P60891
LSFADVMNCVLQKRS

SCN11A

651

Q9UI33
AKIIQCILADVFSNM

SLC9C2

236

Q5TAH2
IISKNMLSLLACVFV

PIEZO1

1226

Q92508
SVAVLTECMRNKILA

PLEKHG1

211

Q9ULL1
MSQFLCLKNIRTFLK

VAV2

66

P52735
RCALSLFLMAVNIKT

UBR4

3991

Q5T4S7
AISAGFLALKICMIR

TMEM273

46

Q5T292
QFTRVMGKVCTQLLV

SAMD4A

496

Q9UPU9
AVALAANAKGMCFIR

TKTL1

431

P51854
AFNSLLAIDICMSKR

PLPP7

81

Q8NBV4
AAIVIQCAFRMLKAR

MYO5B

886

Q9ULV0