Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmRNA cap binding complex binding

SRRT ZC3H18

3.68e-054502GO:0140262
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

DOCK1 ARHGEF38 AKAP13 HERC2 ARHGEF11

2.75e-04231505GO:0005085
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

NEFH SRRT NCOR1 TCF4 RNF20 CIR1 CCAR1 AKAP13 ZC3H18 THRAP3

5.14e-0411605010GO:0030674
GeneOntologyMolecularFunctionK63-linked deubiquitinase activity

USP8 USP9X

7.21e-0416502GO:0061578
GeneOntologyMolecularFunctionK48-linked deubiquitinase activity

USP8 USP9X

1.25e-0321502GO:1990380
GeneOntologyCellularComponentcytoskeletal calyx

CYLC1 CYLC2

1.75e-053512GO:0033150
GeneOntologyCellularComponentnuclear body

DOCK1 SRRT SP100 INTS13 CIR1 ZC3H18 HECTD1 THRAP3 HP1BP3 NCBP3

5.49e-059035110GO:0016604
GeneOntologyCellularComponentperinuclear theca

CYLC1 CYLC2

5.81e-055512GO:0033011
GeneOntologyCellularComponentnuclear speck

DOCK1 CIR1 ZC3H18 HECTD1 THRAP3 HP1BP3 NCBP3

7.98e-05431517GO:0016607
GeneOntologyCellularComponentnuclear protein-containing complex

PCF11 NCOR1 TCF4 SP100 UPF2 INTS13 HLF RSF1 BOD1L1 POLE3 THRAP3 HDAC2

9.12e-0513775112GO:0140513
GeneOntologyCellularComponentISWI-type complex

RSF1 POLE3

5.21e-0414512GO:0031010
GeneOntologyCellularComponentexon-exon junction complex

UPF2 THRAP3

1.19e-0321512GO:0035145
GeneOntologyCellularComponentSWI/SNF superfamily-type complex

RSF1 POLE3 HDAC2

1.67e-0396513GO:0070603
DomainCylicin_N

CYLC1 CYLC2

7.02e-062502IPR029354
DomainCYLC

CYLC1 CYLC2

7.02e-062502IPR026189
DomainCylicin_N

CYLC1 CYLC2

7.02e-062502PF15241
DomainSUZ

ARPP21 R3HDM2

4.20e-054502IPR024771
DomainMib_Herc2

HERC2 HECTD1

4.20e-054502IPR010606
DomainMIB_HERC2

HERC2 HECTD1

4.20e-054502PS51416
DomainMIB_HERC2

HERC2 HECTD1

4.20e-054502PF06701
DomainSUZ

ARPP21 R3HDM2

4.20e-054502PS51673
DomainR3H

ARPP21 R3HDM2

2.50e-049502SM00393
DomainR3H

ARPP21 R3HDM2

3.80e-0411502PS51061
DomainR3H

ARPP21 R3HDM2

3.80e-0411502PF01424
Domain-

ARPP21 R3HDM2

3.80e-04115023.30.1370.50
DomainR3H_dom

ARPP21 R3HDM2

3.80e-0411502IPR001374
DomainDH_1

ARHGEF38 AKAP13 ARHGEF11

6.40e-0463503PS00741
DomainRhoGEF

ARHGEF38 AKAP13 ARHGEF11

8.00e-0468503SM00325
DomainRhoGEF

ARHGEF38 AKAP13 ARHGEF11

8.71e-0470503PF00621
DomainDH_2

ARHGEF38 AKAP13 ARHGEF11

8.71e-0470503PS50010
DomainDH-domain

ARHGEF38 AKAP13 ARHGEF11

9.08e-0471503IPR000219
Domain-

ARHGEF38 AKAP13 ARHGEF11

9.08e-04715031.20.900.10
DomainHECT

HERC2 HECTD1

2.36e-0327502PF00632
DomainHECTc

HERC2 HECTD1

2.36e-0327502SM00119
DomainHECT_dom

HERC2 HECTD1

2.36e-0327502IPR000569
DomainHECT

HERC2 HECTD1

2.36e-0327502PS50237
PathwayREACTOME_RHO_GTPASE_CYCLE

DOCK1 USP9X RNF20 AKAP13 ARHGEF11 FERMT2 PHIP

8.55e-05439357MM15595
PathwayREACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING

ARHGEF38 AKAP13 ARHGEF11 HDAC2

9.36e-0597354M9400
PathwayREACTOME_RHO_GTPASE_CYCLE

DOCK1 USP9X RNF20 AKAP13 ARHGEF11 FERMT2 PHIP

9.98e-05450357M27078
PathwayREACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK

ARHGEF38 AKAP13 ARHGEF11

2.85e-0452353MM14743
PathwayKEGG_MEDICUS_VARIANT_TEL_AML1_FUSION_TO_TRANSCRIPTIONAL_REPRESSION

NCOR1 HDAC2

3.25e-0411352M47438
PathwayREACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK

ARHGEF38 AKAP13 ARHGEF11

4.14e-0459353M11215
PathwayWP_NOTCH_SIGNALING_WP61

NCOR1 CIR1 HDAC2

4.57e-0461353M39540
PathwayREACTOME_DEATH_RECEPTOR_SIGNALING

ARHGEF38 AKAP13 ARHGEF11 HDAC2

5.51e-04154354M27697
PathwayREACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE

ARHGEF38 AKAP13 ARHGEF11

6.85e-0470353MM14824
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIBES_SNRNA_GENES

PCF11 SRRT INTS13

7.74e-0473353MM15349
PathwayREACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE

ARHGEF38 AKAP13 ARHGEF11

8.71e-0476353M19832
PathwayREACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS

ARHGEF38 AKAP13 ARHGEF11

9.04e-0477353MM15044
PathwayREACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

DOCK1 USP9X RNF20 AKAP13 ARHGEF11 FERMT2 PHIP

9.24e-04649357MM15690
PathwayREACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS

ARHGEF38 AKAP13 ARHGEF11

1.01e-0380353M800
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIBES_SNRNA_GENES

PCF11 SRRT INTS13

1.05e-0381353M27647
PathwayWP_DELTANOTCH_SIGNALING_PATHWAY

NCOR1 CIR1 HDAC2

1.09e-0382353MM15922
PathwayREACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING

ARHGEF38 AKAP13 ARHGEF11

1.20e-0385353MM14746
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

PCF11 CYLC1 CYLC2 NCOR1 USP8 SP100 MAP7D1 ZNF608 SEC62 RSF1 EIF5B CCAR1 BOD1L1 PSMD7 RNF17 THRAP3 HP1BP3 HDAC2

8.96e-131442511835575683
Pubmed

RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.

SRRT MAP7D1 KIN UPF2 ATXN2 USP9X EIF5B CCAR1 ZC3H18 DHX29 THRAP3 MYEF2 HP1BP3 NCBP3

1.31e-12713511429802200
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

SRRT NCOR1 UPF2 EIF5B ZC3H18 DDX27 THRAP3 MYEF2 HP1BP3 HDAC2 NCBP3

2.30e-12341511132971831
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

PCF11 SRRT NCOR1 ATXN2 RSF1 ANKRD11 EIF5B CCAR1 BOD1L1 ZC3H18 PHIP THRAP3 HP1BP3 HDAC2 NCBP3

4.26e-12954511536373674
Pubmed

Human transcription factor protein interaction networks.

PCF11 SRRT NCOR1 TCF4 MAP7D1 ZNF608 ATXN2 USP9X CCAR1 R3HDM2 PSMD7 ZC3H18 PAX7 HERC2 DDX27 HP1BP3 HDAC2

9.69e-121429511735140242
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

SRRT MAP7D1 UPF2 RSF1 RNF20 EIF5B CCAR1 AKAP13 PSMD7 HERC2 FERMT2 DHX29 DDX27 PHIP THRAP3 MYEF2

5.00e-111353511629467282
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

USP9X RSF1 EIF5B CCAR1 ZC3H18 HERC2 HECTD1 DDX27 PHIP MYEF2 HP1BP3 HDAC2

1.41e-10653511222586326
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

SRRT NCOR1 INTS13 RSF1 RNF20 EIF5B CCAR1 BOD1L1 ZC3H18 POLE3 THRAP3 HP1BP3 HDAC2

1.74e-091014511332416067
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

DOCK1 SRRT NCOR1 USP9X RSF1 EIF5B AKAP13 RAB11FIP1 DHX29 THRAP3

2.75e-09503511016964243
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

PCF11 SRRT MAP7D1 UPF2 ATXN2 SEC62 CCAR1 HERC2 PIPSL DDX27 THRAP3 HP1BP3 HDAC2 NCBP3

6.75e-091371511436244648
Pubmed

Delineating the HMGB1 and HMGB2 interactome in prostate and ovary epithelial cells and its relationship with cancer.

SRRT RSF1 CCAR1 ZC3H18 THRAP3 HP1BP3 NCBP3

1.14e-0818851729721183
Pubmed

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.

SRRT MAP7D1 KIN UPF2 ATXN2 USP9X EIF5B PSMD7 ZC3H18 DHX29 DDX27 HDAC2

1.22e-08971511233306668
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

PCF11 SRRT USP9X RNF20 HERC2 HECTD1 DHX29 DDX27 MYEF2

1.45e-0844051934244565
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

SRRT ATXN2 EIF5B CCAR1 ZC3H18 DHX29 DDX27 THRAP3 MYEF2 HDAC2 NCBP3

2.01e-08807511122681889
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

PCF11 SRRT MAP7D1 ATXN2 INTS13 ANKRD11 EIF5B CCAR1 HERC2 RAB11FIP1 ARHGEF11 DHX29 DDX27 MYEF2

2.04e-081497511431527615
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

SRRT NCOR1 ATXN2 USP9X EIF5B HERC2 DHX29 PHIP MYEF2

2.81e-0847551931040226
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

SRRT NCOR1 RNF20 CCAR1 THRAP3 MYEF2 HDAC2

3.37e-0822051735785414
Pubmed

The deubiquitinase USP9X regulates FBW7 stability and suppresses colorectal cancer.

USP9X EIF5B HERC2 HECTD1 HDAC2

6.71e-087151529346117
Pubmed

Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.

SRRT NCOR1 USP9X CCAR1 ZC3H18 THRAP3 HP1BP3

6.83e-0824451729884807
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

MAP7D1 KIN UPF2 ATXN2 EIF5B CCAR1 AKAP13 FERMT2 DHX29 THRAP3

8.50e-08724511036232890
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

NEFH NCOR1 MAP7D1 ATXN2 USP9X CCAR1 HERC2 ARHGEF11 THRAP3 MYEF2 HDAC2

1.20e-07963511128671696
Pubmed

Transcription factor protein interactomes reveal genetic determinants in heart disease.

SRRT NCOR1 MAP7D1 INTS13 RSF1 CCAR1 THRAP3 HDAC2

1.45e-0741151835182466
Pubmed

The functional interactome landscape of the human histone deacetylase family.

NCOR1 USP9X ANKRD11 DDX27 PHIP THRAP3 HDAC2

2.15e-0728951723752268
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

SRRT USP9X EIF5B HERC2 DDX27 PHIP THRAP3 MYEF2 HP1BP3 HDAC2 NCBP3

2.21e-071024511124711643
Pubmed

WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.

MAP7D1 ATXN2 USP9X EIF5B DHX29 DDX27 THRAP3 HP1BP3 HDAC2

2.50e-0761551931048545
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

SRRT NCOR1 MAP7D1 INTS13 RNF20 ANKRD11 CCAR1 ZC3H18 POLE3 THRAP3 HP1BP3 HDAC2

2.77e-071294511230804502
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

SP100 UPF2 USP9X RNF20 BOD1L1 PSMD7 PIPSL DHX29 THRAP3 HDAC2

3.60e-07847511035235311
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

PCF11 SRRT KIN UPF2 EIF5B CCAR1 ZC3H18 THRAP3 MYEF2 HP1BP3 HDAC2

3.83e-071082511138697112
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

SP100 MAP7D1 MCTP1 ZNF608 INTS13 RSF1 ZC3H18 RAB11FIP1 PHIP MYEF2 HDAC2

5.19e-071116511131753913
Pubmed

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.

MAP7D1 EIF5B PSMD7 ZC3H18 PIPSL DHX29 DDX27 HDAC2

6.02e-0749651831343991
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

MAP7D1 USP9X ANKRD11 CCAR1 PSMD7 ARHGEF11 HP1BP3 NCBP3

6.11e-0749751836774506
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

USP9X EIF5B BOD1L1 FERMT2 DHX29 PHIP MYEF2 HP1BP3

6.20e-0749851836634849
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

SRRT USP8 MAP7D1 USP9X RNF20 EIF5B AKAP13 ZC3H18 HECTD1 THRAP3 HP1BP3 HDAC2

7.15e-071415511228515276
Pubmed

Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.

SRRT MAP7D1 AKAP13 ZC3H18 THRAP3 HP1BP3 HDAC2

9.58e-0736151730344098
Pubmed

TRIM65 regulates microRNA activity by ubiquitination of TNRC6.

SRRT UPF2 ATXN2 HECTD1 DDX27 THRAP3 HP1BP3

1.01e-0636451724778252
Pubmed

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

INTS13 RSF1 EIF5B ZC3H18 HERC2 DDX27 PHIP HP1BP3

1.03e-0653351830554943
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

PCF11 ANKRD11 EIF5B AKAP13 PSMD7 HERC2 RAB11FIP1 FERMT2 DHX29 DDX27 HP1BP3 NCBP3

1.20e-061487511233957083
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

SRRT KIN UPF2 HERC2 HECTD1 DHX29 DDX27 HP1BP3 NCBP3

1.44e-0675951935915203
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

SRRT SP100 MAP7D1 KIN UPF2 ATXN2 EIF5B ZC3H18 DDX27 THRAP3 HP1BP3

1.66e-061257511136526897
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

PCF11 SRRT NCOR1 RNF20 EIF5B CCAR1 ZC3H18 DHX29 THRAP3

1.69e-0677451915302935
Pubmed

SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.

RSF1 CCAR1 BOD1L1 ZC3H18 THRAP3 HP1BP3

1.83e-0625151631076518
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

SRRT USP8 MAP7D1 ATXN2 USP9X AKAP13 PSMD7 HERC2 RAB11FIP1 DDX27 THRAP3

2.04e-061284511117353931
Pubmed

The protein complexity of the cytoskeleton of bovine and human sperm heads: the identification and characterization of cylicin II.

CYLC1 CYLC2

2.11e-0625127737358
Pubmed

Cylicins are a structural component of the sperm calyx being indispensable for male fertility in mice and human.

CYLC1 CYLC2

2.11e-06251238013430
Pubmed

NCBP3 positively impacts mRNA biogenesis.

ZC3H18 NCBP3

2.11e-06251232960271
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

SRRT CCAR1 ZC3H18 DDX27 THRAP3 HP1BP3 HDAC2 NCBP3

2.64e-0660551828977666
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

RSF1 BOD1L1 ZC3H18 HERC2 PHIP HP1BP3 HDAC2 NCBP3

2.74e-0660851836089195
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

SRRT USP8 MAP7D1 ANKRD11 AKAP13 BOD1L1 PSMD7 RAB11FIP1 HECTD1

4.01e-0686151936931259
Pubmed

A bead-based approach for large-scale identification of in vitro kinase substrates.

SRRT RSF1 EIF5B THRAP3 HDAC2

4.20e-0616351522113938
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

SRRT EIF5B ZC3H18 ARHGEF11 THRAP3 HP1BP3 HDAC2 NCBP3

5.00e-0666051832780723
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

SRRT USP9X RNF20 EIF5B CCAR1 BOD1L1 PSMD7 DHX29 DDX27 PHIP THRAP3

5.53e-061425511130948266
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

NEFH SRRT MAP7D1 UPF2 USP9X ARHGEF11 FERMT2 DHX29 THRAP3 MYEF2 HP1BP3

5.75e-061431511137142655
Pubmed

RNF20 Functions as a Transcriptional Coactivator for PPARγ by Promoting NCoR1 Degradation in Adipocytes.

NCOR1 RNF20

6.32e-06351231604693
Pubmed

Mutually Exclusive CBC-Containing Complexes Contribute to RNA Fate.

SRRT ZC3H18

6.32e-06351228297668
Pubmed

Comparative interactome analysis of α-arrestin families in human and Drosophila.

USP9X BOD1L1 ZC3H18 HERC2 THRAP3 HDAC2

6.49e-0631351638270169
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

DOCK1 SRRT MAP7D1 CCAR1 AKAP13 PSMD7 ARHGEF11 HP1BP3 HDAC2

6.61e-0691651932203420
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

SRRT USP8 SP100 INTS13 USP9X RNF20 EIF5B PSMD7 POLE3 FERMT2 HECTD1

6.74e-061455511122863883
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

DOCK1 ZNF608 ATXN2 ARHGEF38 ANKRD11 CCAR1 AKAP13 BOD1L1 HECTD1 THRAP3 HP1BP3

8.38e-061489511128611215
Pubmed

A comprehensive resource of interacting protein regions for refining human transcription factor networks.

UPF2 INTS13 SEC62 EIF5B HDAC2

9.07e-0619151520195357
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

SP100 DHX29 DDX27 PHIP HP1BP3 NCBP3

9.07e-0633251625693804
Pubmed

Tagging genes with cassette-exchange sites.

NCOR1 USP9X AKAP13 RNF17 DHX29 DDX27

9.55e-0633551615741177
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

USP8 USP9X EIF5B ARHGEF11 FERMT2 HECTD1

1.11e-0534451630333137
Pubmed

Control of developmentally primed erythroid genes by combinatorial co-repressor actions.

NCOR1 TCF4 HDAC2

1.17e-053051326593974
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

DOCK1 EIF5B AKAP13 HERC2 HECTD1

1.19e-0520251533005030
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

SRRT UPF2 EIF5B ZC3H18 THRAP3

1.19e-0520251524639526
Pubmed

The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.

ATXN2 RSF1 DDX27 PHIP HP1BP3 HDAC2

1.20e-0534951625665578
Pubmed

Silencing mediator for retinoid and thyroid hormone receptor and nuclear receptor corepressor attenuate transcriptional activation by the beta-catenin-TCF4 complex.

NCOR1 TCF4

1.26e-05451218632669
Pubmed

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.

SRRT RSF1 ZC3H18 HDAC2

1.63e-0510351432744500
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

NCOR1 UPF2 EIF5B CCAR1 PSMD7 DDX27 PHIP THRAP3 HP1BP3 HDAC2

1.83e-051318511030463901
Pubmed

TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation.

TCF4 R3HDM2 PHIP MYEF2

2.04e-0510951433554859
Pubmed

Karyopherin Alpha 1 Regulates Satellite Cell Proliferation and Survival by Modulating Nuclear Import.

SRRT PAX7 HP1BP3

2.05e-053651327434733
Pubmed

Styxl2 regulates de novo sarcomere assembly by binding to non-muscle myosin IIs and promoting their degradation.

STYXL2 PAX7

2.10e-05551238829202
Pubmed

Satellite cells, connective tissue fibroblasts and their interactions are crucial for muscle regeneration.

TCF4 PAX7

2.10e-05551221828091
Pubmed

Epstein-Barr virus nuclear antigen 3C recruits histone deacetylase activity and associates with the corepressors mSin3A and NCoR in human B-cell lines.

NCOR1 HDAC2

2.10e-05551212634383
Pubmed

Expression of nuclear receptor corepressors and class I histone deacetylases in astrocytic gliomas.

NCOR1 HDAC2

2.10e-05551221143702
Pubmed

Kindlin 2 forms a transcriptional complex with β-catenin and TCF4 to enhance Wnt signalling.

TCF4 FERMT2

2.10e-05551222699938
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

SRRT TCF4 MAP7D1 USP9X CCAR1 DHX29

2.45e-0539651626687479
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

PCF11 NCOR1 MAP7D1 ATXN2 EIF5B CCAR1 PSMD7 THRAP3 HDAC2

2.88e-05110351934189442
Pubmed

CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex.

CIR1 HDAC2

3.15e-0565129874765
Pubmed

Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.

EIF5B ZC3H18 MYEF2 HP1BP3 HDAC2

3.37e-0525151528077445
Pubmed

Cancer-associated exportin-6 upregulation inhibits the transcriptionally repressive and anticancer effects of nuclear profilin-1.

DOCK1 BOD1L1 HP1BP3

4.04e-054551333596420
Pubmed

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

USP9X RNF20 CCAR1 PSMD7 PIPSL DHX29 THRAP3 HP1BP3 HDAC2

4.07e-05115351929845934
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

ZNF608 RSF1 RNF20 CCAR1 PSMD7 PHIP THRAP3

4.17e-0564551725281560
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

SRRT MAP7D1 UPF2 RNF20 CCAR1 AKAP13 HP1BP3

4.37e-0565051738777146
Pubmed

Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR.

NCOR1 HDAC2

4.41e-05751211804585
Pubmed

Cell fate determination factor DACH1 inhibits c-Jun-induced contact-independent growth.

NCOR1 HDAC2

4.41e-05751217182846
Pubmed

The peroxisome proliferator-activated receptor delta, an integrator of transcriptional repression and nuclear receptor signaling.

NCOR1 HDAC2

4.41e-05751211867749
Pubmed

A role for SKIP in EBNA2 activation of CBF1-repressed promoters.

CIR1 HDAC2

4.41e-05751210644367
Pubmed

Unraveling the hidden catalytic activity of vertebrate class IIa histone deacetylases.

NCOR1 HDAC2

4.41e-05751217956988
Pubmed

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.

SRRT USP9X SEC62 RSF1 PSMD7 DDX27 NCBP3

4.50e-0565351733742100
Pubmed

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

CIR1 EIF5B ZC3H18 DDX27 THRAP3 MYEF2 HP1BP3

4.59e-0565551735819319
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

PCF11 NCOR1 ZNF608 INTS13 RNF20

4.60e-0526851533640491
Pubmed

Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the centromeric region in interphase.

SRRT RSF1 PHIP

4.60e-054751315009096
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

ZNF608 ANKRD11 BOD1L1 THRAP3 HDAC2

4.94e-0527251531010829
Pubmed

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.

SRRT USP9X CCAR1 PSMD7 ZC3H18 THRAP3 HP1BP3

5.05e-0566551730457570
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

SRRT ATXN2 CCAR1 THRAP3 NCBP3

5.11e-0527451534244482
Pubmed

Global landscape of HIV-human protein complexes.

NCOR1 SEC62 PSMD7 POLE3 HERC2 THRAP3

5.44e-0545751622190034
Pubmed

TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.

SRRT KIN ATXN2 USP9X ANKRD11 ZC3H18 HERC2 THRAP3

5.49e-0592251827609421
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

NCOR1 USP9X BOD1L1 FERMT2 MYEF2

5.86e-0528251523667531
Pubmed

HDAC3 Is a Master Regulator of mTEC Development.

NCOR1 HDAC2

5.87e-05851227068467
InteractionTERF2IP interactions

PCF11 NCOR1 SP100 ARPP21 ZNF608 RSF1 RNF20 ANKRD11 CCAR1 BOD1L1 ZC3H18 HECTD1 HP1BP3

7.80e-105525113int:TERF2IP
InteractionSNRNP70 interactions

SRRT MAP7D1 KIN UPF2 ATXN2 USP9X EIF5B CCAR1 ZC3H18 HECTD1 DHX29 THRAP3 MYEF2 HP1BP3 HDAC2 NCBP3

1.32e-099845116int:SNRNP70
InteractionSMC5 interactions

PCF11 SRRT NCOR1 ATXN2 RSF1 ANKRD11 EIF5B CCAR1 BOD1L1 ZC3H18 HECTD1 PHIP THRAP3 HP1BP3 HDAC2 NCBP3

1.67e-0910005116int:SMC5
InteractionOBSL1 interactions

SRRT MAP7D1 EIF5B PSMD7 HERC2 PIPSL HECTD1 DHX29 DDX27 PHIP THRAP3 MYEF2 HP1BP3 HDAC2 NCBP3

3.63e-099025115int:OBSL1
InteractionMEN1 interactions

PCF11 SRRT NCOR1 ZNF608 UPF2 RNF20 EIF5B BOD1L1 ZC3H18 DDX27 THRAP3 MYEF2 HP1BP3 HDAC2 NCBP3

2.13e-0810295115int:MEN1
InteractionNUP43 interactions

SRRT NCOR1 ZNF608 RSF1 ANKRD11 BOD1L1 ZC3H18 DDX27 PHIP HP1BP3 HDAC2 NCBP3

3.74e-086255112int:NUP43
InteractionSMG7 interactions

PCF11 NCOR1 ZNF608 ATXN2 RNF20 CCAR1 R3HDM2 PSMD7 PHIP

9.46e-08319519int:SMG7
InteractionSSRP1 interactions

PCF11 SRRT NCOR1 INTS13 RSF1 ANKRD11 CCAR1 ZC3H18 POLE3 HECTD1 PHIP THRAP3

1.02e-076855112int:SSRP1
InteractionTOP1 interactions

PCF11 SRRT SP100 RSF1 CCAR1 ZC3H18 POLE3 HERC2 HECTD1 DHX29 THRAP3 HP1BP3

1.21e-076965112int:TOP1
InteractionSRPK2 interactions

PCF11 SRRT MAP7D1 CCAR1 AKAP13 ZC3H18 HECTD1 DDX27 THRAP3 MYEF2 HP1BP3 NCBP3

1.67e-077175112int:SRPK2
InteractionHDAC4 interactions

SRRT NCOR1 ATXN2 USP9X ANKRD11 EIF5B POLE3 HERC2 DHX29 PHIP THRAP3 MYEF2

2.48e-077445112int:HDAC4
InteractionSIRT7 interactions

USP9X RSF1 EIF5B CCAR1 ZC3H18 HERC2 HECTD1 DDX27 PHIP MYEF2 HP1BP3 HDAC2

2.48e-077445112int:SIRT7
InteractionAR interactions

PCF11 SRRT NCOR1 TCF4 ZNF608 INTS13 RNF20 CCAR1 PSMD7 RAB11FIP1 THRAP3 MYEF2 HDAC2

7.66e-079925113int:AR
InteractionFXR1 interactions

NCOR1 UPF2 ATXN2 USP9X CIR1 CCAR1 HERC2 HECTD1 THRAP3 MYEF2 HDAC2

8.17e-076795111int:FXR1
InteractionALYREF interactions

PCF11 SRRT KIN UPF2 RNF20 ZC3H18 HECTD1 THRAP3 NCBP3

8.81e-07416519int:ALYREF
InteractionMYCN interactions

SRRT TCF4 MAP7D1 UPF2 ATXN2 EIF5B AKAP13 PSMD7 ZC3H18 DDX27 THRAP3 MYEF2 HP1BP3 HDAC2 NCBP3

9.03e-0713735115int:MYCN
InteractionHMGA1 interactions

UPF2 USP9X RSF1 ZC3H18 POLE3 PHIP THRAP3 HP1BP3 HDAC2

9.36e-07419519int:HMGA1
InteractionHNRNPK interactions

SRRT RNF20 CCAR1 ZC3H18 RAB11FIP1 FERMT2 HECTD1 DDX27 PHIP MYEF2 HP1BP3 HDAC2

1.06e-068535112int:HNRNPK
InteractionATXN1 interactions

SRRT NCOR1 SP100 ATXN2 USP9X CCAR1 R3HDM2 PSMD7 ZC3H18 PAX7 THRAP3 MYEF2 HP1BP3

1.29e-0610395113int:ATXN1
InteractionRBM39 interactions

SRRT SP100 MAP7D1 KIN ATXN2 CCAR1 ZC3H18 HERC2 HECTD1 THRAP3 MYEF2 HP1BP3 NCBP3

1.33e-0610425113int:RBM39
InteractionRPS6 interactions

MAP7D1 UPF2 ATXN2 RSF1 EIF5B ZC3H18 RNF17 DHX29 DDX27 PHIP MYEF2 HP1BP3

1.37e-068745112int:RPS6
InteractionMAGOHB interactions

TCF4 UPF2 ZC3H18 PAX7 HERC2 THRAP3

2.54e-06155516int:MAGOHB
InteractionTAF6 interactions

SRRT NCOR1 SP100 BOD1L1 POLE3 PHIP HDAC2

2.64e-06245517int:TAF6
InteractionHMGB1 interactions

CYLC2 SRRT SP100 RSF1 EIF5B CCAR1 ZC3H18 THRAP3 HP1BP3

3.17e-06486519int:HMGB1
InteractionSIRT6 interactions

PCF11 SRRT USP9X RNF20 HERC2 HECTD1 DHX29 DDX27 MYEF2 HDAC2

3.24e-066285110int:SIRT6
InteractionSNRNP40 interactions

SRRT NCOR1 KIN ZNF608 RSF1 CCAR1 ZC3H18 HECTD1 DDX27 HDAC2

3.68e-066375110int:SNRNP40
InteractionPRC1 interactions

SRRT RSF1 EIF5B PSMD7 ZC3H18 HECTD1 DHX29 DDX27 PHIP THRAP3 HP1BP3 HDAC2

4.16e-069735112int:PRC1
InteractionALG13 interactions

PCF11 NCOR1 ZNF608 ATXN2 CCAR1 R3HDM2

6.63e-06183516int:ALG13
InteractionFBXO22 interactions

NCOR1 MAP7D1 USP9X ANKRD11 CCAR1 PSMD7 ARHGEF11 HP1BP3 NCBP3

7.44e-06540519int:FBXO22
InteractionSUPT5H interactions

PCF11 NCOR1 INTS13 RNF20 EIF5B ZC3H18 THRAP3 NCBP3

7.83e-06408518int:SUPT5H
InteractionSMARCA5 interactions

SRRT RSF1 ZC3H18 POLE3 PIPSL HECTD1 PHIP HDAC2

8.87e-06415518int:SMARCA5
InteractionEED interactions

SRRT NCOR1 USP9X EIF5B CCAR1 POLE3 HERC2 FERMT2 HECTD1 DDX27 THRAP3 MYEF2 HP1BP3 HDAC2

9.27e-0614455114int:EED
InteractionSRSF4 interactions

USP9X ZC3H18 HERC2 DDX27 THRAP3 HP1BP3 NCBP3

9.98e-06300517int:SRSF4
InteractionARRDC2 interactions

USP9X BOD1L1 PIPSL HDAC2

1.05e-0554514int:ARRDC2
InteractionTP63 interactions

CYLC2 USP8 TCF4 UPF2 SEC62 FERMT2 HDAC2

1.09e-05304517int:TP63
InteractionMECP2 interactions

PCF11 SRRT NCOR1 SP100 KIN UPF2 EIF5B CCAR1 ZC3H18 THRAP3 MYEF2 HP1BP3 HDAC2

1.34e-0512875113int:MECP2
InteractionZNF330 interactions

KIN RSF1 ANKRD11 ZC3H18 DDX27 PHIP HP1BP3 NCBP3

1.49e-05446518int:ZNF330
InteractionYWHAZ interactions

NCOR1 USP8 MAP7D1 MCTP1 RSF1 AKAP13 R3HDM2 ZC3H18 HERC2 RAB11FIP1 FERMT2 HECTD1 HDAC2

1.74e-0513195113int:YWHAZ
InteractionCHD4 interactions

SRRT RSF1 CCAR1 ZC3H18 HECTD1 DDX27 PHIP THRAP3 HP1BP3 HDAC2 NCBP3

1.80e-059385111int:CHD4
InteractionMACROH2A1 interactions

SRRT SP100 USP9X RSF1 ZC3H18 HECTD1 THRAP3 HDAC2

1.81e-05458518int:MACROH2A1
InteractionPRP4K interactions

SRRT SP100 UPF2 AKAP13 ZC3H18 HECTD1 THRAP3

1.81e-05329517int:PRP4K
InteractionCSNK2A1 interactions

SRRT NCOR1 ATXN2 RSF1 ANKRD11 EIF5B ZC3H18 PAX7 THRAP3 HP1BP3 HDAC2

2.15e-059565111int:CSNK2A1
InteractionDNAJC17 interactions

PCF11 KIN ANKRD11 DHX29 NCBP3

2.22e-05134515int:DNAJC17
InteractionGPATCH4 interactions

SP100 ZC3H18 HECTD1 DDX27 MYEF2 HP1BP3

2.55e-05232516int:GPATCH4
InteractionBUB3 interactions

BOD1L1 ZC3H18 HERC2 HECTD1 PHIP HDAC2

2.55e-05232516int:BUB3
InteractionSND1 interactions

SEC62 EIF5B ZC3H18 HECTD1 DHX29 THRAP3 HP1BP3

2.55e-05347517int:SND1
InteractionNANOG interactions

NCOR1 TCF4 INTS13 USP9X PSMD7 DDX27 MYEF2 HDAC2

2.57e-05481518int:NANOG
InteractionSRRM1 interactions

PCF11 UPF2 USP9X EIF5B AKAP13 ZC3H18 HERC2

2.60e-05348517int:SRRM1
InteractionFZR1 interactions

SRRT MAP7D1 KIN UPF2 ATXN2 USP9X EIF5B PSMD7 ZC3H18 DHX29 DDX27 HDAC2

2.71e-0511725112int:FZR1
InteractionHECTD1 interactions

SRRT KIN UPF2 USP9X ANKRD11 HERC2 HECTD1 DHX29 DDX27 HP1BP3 NCBP3

2.80e-059845111int:HECTD1
InteractionNCBP1 interactions

SRRT ATXN2 RNF20 BOD1L1 ZC3H18 HECTD1 NCBP3

2.84e-05353517int:NCBP1
InteractionFAM98A interactions

ATXN2 RNF20 R3HDM2 ZC3H18 HERC2 HECTD1

2.87e-05237516int:FAM98A
InteractionPOLR1G interactions

RSF1 ANKRD11 PSMD7 ZC3H18 HECTD1 DDX27 PHIP NCBP3

2.89e-05489518int:POLR1G
InteractionPABPC5 interactions

SRRT ATXN2 ZC3H18 DHX29 NCBP3

2.93e-05142515int:PABPC5
InteractionMYCBP2 interactions

CCAR1 HERC2 ARHGEF11 HECTD1 THRAP3 MYEF2 HDAC2

2.95e-05355517int:MYCBP2
InteractionPYHIN1 interactions

RSF1 EIF5B ZC3H18 PHIP MYEF2 HP1BP3 HDAC2

3.11e-05358517int:PYHIN1
InteractionEP300 interactions

SRRT NCOR1 TCF4 USP9X SEC62 RSF1 PSMD7 PAX7 HECTD1 DDX27 THRAP3 HDAC2 NCBP3

3.30e-0514015113int:EP300
InteractionZNF609 interactions

SP100 ZNF608 PAX7 PHIP HDAC2

3.35e-05146515int:ZNF609
InteractionMATR3 interactions

NCOR1 MCTP1 USP9X ZC3H18 HERC2 HECTD1 THRAP3 MYEF2 HDAC2

3.44e-05655519int:MATR3
InteractionCTNNB1 interactions

USP8 TCF4 USP9X SEC62 CCAR1 PSMD7 HERC2 FERMT2 HECTD1 THRAP3 HDAC2

3.53e-0510095111int:CTNNB1
InteractionKPNA3 interactions

USP9X ANKRD11 BOD1L1 ZC3H18 THRAP3 HDAC2

3.70e-05248516int:KPNA3
InteractionHS3ST3A1 interactions

UPF2 PIPSL

3.76e-054512int:HS3ST3A1
InteractionDHX40 interactions

PCF11 ANKRD11 ZC3H18 DDX27 THRAP3 NCBP3

3.79e-05249516int:DHX40
InteractionH2AZ1 interactions

UPF2 RSF1 ZC3H18 PHIP THRAP3 HP1BP3 HDAC2

3.90e-05371517int:H2AZ1
InteractionTLE3 interactions

SRRT NCOR1 TCF4 ZNF608 INTS13 CCAR1 PAX7

4.25e-05376517int:TLE3
InteractionCUL7 interactions

SRRT EIF5B ZC3H18 HECTD1 DDX27 PHIP THRAP3 MYEF2 HP1BP3 HDAC2

4.26e-058455110int:CUL7
InteractionKIF23 interactions

SRRT USP8 RSF1 EIF5B CCAR1 ZC3H18 PIPSL HECTD1 DDX27 PHIP THRAP3

4.30e-0510315111int:KIF23
InteractionGSE1 interactions

TCF4 SP100 PAX7 PHIP HDAC2

4.32e-05154515int:GSE1
InteractionSNRPB2 interactions

SRRT MAP7D1 EIF5B CCAR1 ZC3H18 THRAP3

4.33e-05255516int:SNRPB2
InteractionHNRNPU interactions

ATXN2 SEC62 CCAR1 PSMD7 ZC3H18 HECTD1 DHX29 DDX27 THRAP3 HP1BP3 HDAC2

4.46e-0510355111int:HNRNPU
InteractionEFTUD2 interactions

SRRT USP8 MAP7D1 KIN USP9X RNF20 EIF5B AKAP13 ZC3H18 HECTD1 THRAP3 HP1BP3 HDAC2

4.69e-0514495113int:EFTUD2
InteractionRRP15 interactions

RSF1 ZC3H18 HECTD1 DDX27 THRAP3

4.74e-05157515int:RRP15
InteractionH2BC21 interactions

CYLC1 USP8 RSF1 RNF20 ZC3H18 POLE3 PHIP HP1BP3 HDAC2

5.50e-05696519int:H2BC21
InteractionRPL13 interactions

MAP7D1 UPF2 ZC3H18 HERC2 HECTD1 DHX29 DDX27 HP1BP3 HDAC2

5.75e-05700519int:RPL13
InteractionSGF29 interactions

TCF4 ZNF608 RNF20 BOD1L1 HECTD1

5.83e-05164515int:SGF29
InteractionPHAX interactions

PCF11 SRRT USP9X HECTD1 THRAP3

6.35e-05167515int:PHAX
InteractionZC3H14 interactions

ZC3H18 HECTD1 THRAP3 HDAC2 NCBP3

6.72e-05169515int:ZC3H14
InteractionSNCA interactions

SRRT USP8 USP9X EIF5B FERMT2 DHX29 PHIP MYEF2 HP1BP3

6.85e-05716519int:SNCA
InteractionRBM14 interactions

PCF11 SRRT USP9X ZC3H18 HECTD1 THRAP3 HP1BP3 HDAC2

6.88e-05553518int:RBM14
InteractionTWIST1 interactions

TCF4 R3HDM2 PHIP MYEF2 HDAC2

6.91e-05170515int:TWIST1
InteractionTHOC6 interactions

ZC3H18 HERC2 HECTD1 NCBP3

6.93e-0587514int:THOC6
InteractionRPL14 interactions

KIN ZC3H18 HECTD1 DHX29 DDX27 MYEF2 HP1BP3 HDAC2

6.97e-05554518int:RPL14
InteractionDDX21 interactions

SRRT KIN ZC3H18 POLE3 HECTD1 DDX27 THRAP3 HP1BP3 HDAC2

7.00e-05718519int:DDX21
InteractionEGLN3 interactions

PCF11 NCOR1 TCF4 ATXN2 INTS13 USP9X ANKRD11 AKAP13 PSMD7 POLE3 PIPSL HECTD1

7.23e-0512965112int:EGLN3
InteractionRCOR3 interactions

SP100 ANKRD11 PAX7 PHIP HDAC2

7.30e-05172515int:RCOR3
InteractionGATA4 interactions

SRRT NCOR1 SP100 INTS13 RSF1 THRAP3 HDAC2

7.44e-05411517int:GATA4
InteractionCPSF2 interactions

PCF11 SRRT POLE3 HECTD1 HDAC2

7.51e-05173515int:CPSF2
InteractionWDR5 interactions

SRRT MAP7D1 ZNF608 BOD1L1 ZC3H18 PAX7 POLE3 HECTD1 DDX27 THRAP3 HDAC2

7.79e-0511015111int:WDR5
InteractionYWHAH interactions

SRRT USP8 MAP7D1 ANKRD11 AKAP13 R3HDM2 BOD1L1 PSMD7 RAB11FIP1 FERMT2 HECTD1

7.85e-0511025111int:YWHAH
InteractionDDX5 interactions

TCF4 KIN ATXN2 ZC3H18 RAB11FIP1 HECTD1 THRAP3 HDAC2

8.29e-05568518int:DDX5
InteractionPPP1CC interactions

SRRT NCOR1 MAP7D1 AKAP13 ZC3H18 RAB11FIP1 THRAP3 HP1BP3 HDAC2

8.63e-05738519int:PPP1CC
InteractionRNPS1 interactions

SRRT UPF2 ZC3H18 HERC2 HECTD1 THRAP3 NCBP3

9.18e-05425517int:RNPS1
InteractionHCFC1 interactions

NCOR1 ZNF608 BOD1L1 PSMD7 POLE3 HDAC2

9.33e-05293516int:HCFC1
InteractionUPF1 interactions

UPF2 ATXN2 RNF20 R3HDM2 ZC3H18 HERC2 HECTD1 THRAP3

9.71e-05581518int:UPF1
InteractionNIFK interactions

NEFH USP9X ANKRD11 ZC3H18 HECTD1 DDX27 NCBP3

1.00e-04431517int:NIFK
InteractionSFSWAP interactions

CCAR1 ZC3H18 HERC2 HECTD1

1.02e-0496514int:SFSWAP
InteractionCHD3 interactions

SRRT CCAR1 ZC3H18 HECTD1 DDX27 THRAP3 HP1BP3 HDAC2 NCBP3

1.05e-04757519int:CHD3
InteractionGATA3 interactions

PCF11 NCOR1 USP9X CCAR1 HDAC2

1.08e-04187515int:GATA3
InteractionSUMO2 interactions

SRRT NCOR1 SP100 USP9X RNF20 BOD1L1 HP1BP3 HDAC2

1.09e-04591518int:SUMO2
InteractionBCOR interactions

NCOR1 SP100 ZNF608 ZC3H18 PAX7 PHIP

1.10e-04302516int:BCOR
CytobandEnsembl 112 genes in cytogenetic band chr10p14

KIN UPF2

1.38e-0349512chr10p14
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ARHGEF38 AKAP13 ARHGEF11

1.94e-0466313722
GeneFamilyUbiquitin specific peptidases

USP8 USP9X

4.14e-0356312366
GeneFamilyPHD finger proteins

SP100 RSF1

1.04e-029031288
CoexpressionMARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN

TCF4 KIN ATXN2 SEC62 RNF20 EIF5B CCAR1 POLE3 FERMT2 DHX29 THRAP3 HP1BP3

2.52e-105195112M3395
CoexpressionMARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN

TCF4 KIN ATXN2 SEC62 RNF20 EIF5B CCAR1 POLE3 FERMT2 DHX29 THRAP3 HP1BP3

4.22e-105435112MM997
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

USP8 TCF4 USP9X SEC62 RSF1 RNF20 EIF5B CCAR1 HECTD1 DHX29 MYEF2 HDAC2

3.56e-096565112M18979
CoexpressionLAKE_ADULT_KIDNEY_C5_PROXIMAL_TUBULE_EPITHELIAL_CELLS_STRESS_INFLAM

SRRT NCOR1 USP8 MCTP1 UPF2 ANKRD11 EIF5B CCAR1 AKAP13

1.01e-07417519M39224
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

PCF11 DOCK1 SP100 KIN UPF2 ATXN2 USP9X AKAP13 R3HDM2 FERMT2 PHIP

6.10e-078565111M4500
CoexpressionTIEN_INTESTINE_PROBIOTICS_6HR_DN

SRRT TCF4 KIN INTS13 FERMT2 DHX29

9.64e-07170516M19990
CoexpressionGSE14000_TRANSLATED_RNA_VS_MRNA_4H_LPS_DC_UP

INTS13 SEC62 CCAR1 HECTD1 DHX29 NCBP3

2.41e-06199516M3328
CoexpressionGSE40274_FOXP3_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN

PCF11 KIN AKAP13 BOD1L1 HECTD1

8.65e-06143515M9149
CoexpressionHOFFMANN_PRE_BI_TO_LARGE_PRE_BII_LYMPHOCYTE_UP

KIN SEC62 MYEF2

2.20e-0528513MM801
CoexpressionHOFFMANN_PRE_BI_TO_LARGE_PRE_BII_LYMPHOCYTE_UP

KIN SEC62 MYEF2

2.45e-0529513M5589
CoexpressionEIF4E_DN

DOCK1 UPF2 CCAR1 PHIP

4.34e-05100514M2790
CoexpressionGSE17721_LPS_VS_POLYIC_6H_BMDC_UP

ATXN2 BOD1L1 PSMD7 HERC2 DDX27

4.35e-05200515M3808
CoexpressionHOUNKPE_HOUSEKEEPING_GENES

SEC62 RNF20 EIF5B PSMD7 ZC3H18 POLE3 DHX29 DDX27 THRAP3 HP1BP3

5.39e-0511295110M42508
CoexpressionHOUNKPE_HOUSEKEEPING_GENES

SEC62 RNF20 EIF5B PSMD7 ZC3H18 POLE3 DHX29 DDX27 THRAP3 HP1BP3

6.66e-0511585110MM1338
CoexpressionBERENJENO_ROCK_SIGNALING_NOT_VIA_RHOA_DN

ATXN2 BOD1L1 FERMT2

1.13e-0448513M10253
CoexpressionBERENJENO_ROCK_SIGNALING_NOT_VIA_RHOA_DN

ATXN2 BOD1L1 FERMT2

1.13e-0448513MM1088
CoexpressionKENNY_CTNNB1_TARGETS_DN

NCOR1 USP9X SEC62

1.43e-0452513M19134
CoexpressionSHEN_SMARCA2_TARGETS_UP

NCOR1 UPF2 USP9X SEC62 HERC2 DHX29

1.79e-04429516M29
CoexpressionGARY_CD5_TARGETS_DN

SRRT RNF20 CCAR1 POLE3 DHX29 DDX27

2.06e-04440516M13893
CoexpressionHOSHIDA_LIVER_CANCER_LATE_RECURRENCE_UP

TCF4 AKAP13 HDAC2

2.42e-0462513M6176
CoexpressionGABRIELY_MIR21_TARGETS

RSF1 FERMT2 HECTD1 PHIP MYEF2

2.44e-04289515M2196
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

UPF2 ATXN2 USP9X R3HDM2 FERMT2 PHIP

2.80e-04466516M13522
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1

PCF11 DOCK1 TCF4 UPF2 RSF1 ANKRD11 CIR1 EIF5B CCAR1 FERMT2 HECTD1 PHIP

6.65e-104695012Facebase_RNAseq_e8.5_Floor Plate_2500_K1
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#5_top-relative-expression-ranked_1000

DOCK1 USP9X RSF1 HERC2 FERMT2 PHIP MYEF2 HDAC2

3.76e-06397508gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000_k5
CoexpressionAtlasFacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#2

MAP7D1 KIN UPF2 INTS13 RNF20 CIR1 POLE3 HECTD1 DHX29

5.86e-06564509Facebase_RNAseq_e9.5_Mandibular Arch_2500_K2
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#4

KIN UPF2 INTS13 SEC62 RNF20 CIR1 BOD1L1 POLE3 HECTD1

9.01e-06595509Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K4
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#2_top-relative-expression-ranked_1000

DOCK1 USP9X RSF1 HERC2 PHIP MYEF2 HDAC2

1.16e-05330507DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k2_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5

KIN UPF2 INTS13 RNF20 CIR1 CCAR1 BOD1L1 HECTD1 PHIP

1.40e-05629509Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
CoexpressionAtlasFetal Liver, SC.LTSL.FL, IgM- CD24- CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Fetal Liver, avg-3

DOCK1 MCTP1 ZNF608 HLF

6.52e-0592504GSM791126_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_top-relative-expression-ranked_1000

DOCK1 NCOR1 USP9X RSF1 HERC2 FERMT2 PHIP MYEF2 HDAC2

1.01e-04811509gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

KIN UPF2 INTS13 USP9X RSF1 RNF20 EIF5B CCAR1 BOD1L1 PHIP THRAP3

1.32e-0412575011facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3

PCF11 RSF1 ANKRD11 EIF5B FERMT2 PHIP THRAP3

2.34e-04532507Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500

KIN UPF2 INTS13 USP9X RSF1 RNF20 EIF5B CCAR1 BOD1L1 PHIP THRAP3

4.79e-0414595011facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlasfacebase_RNAseq_e10.5_MandArch_2500

SP100 KIN INTS13 USP9X RSF1 EIF5B CCAR1 BOD1L1 PHIP THRAP3 HDAC2

5.05e-0414685011facebase_RNAseq_e10.5_MandArch_2500
CoexpressionAtlasfacebase_RNAseq_e10.5_MandArch_2500_K1

KIN INTS13 USP9X RSF1 EIF5B CCAR1 BOD1L1 PHIP THRAP3 HDAC2

5.40e-0412415010facebase_RNAseq_e10.5_MandArch_2500_K1
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_1000

ATXN2 RSF1 ANKRD11 EIF5B PSMD7 RNF17 THRAP3 HDAC2

5.44e-04806508gudmap_developingGonad_e12.5_epididymis_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#5_top-relative-expression-ranked_500

USP9X PHIP MYEF2 HDAC2

6.13e-04165504DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k5_500
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

NEFH UPF2 RSF1 CIR1 EIF5B CCAR1 BOD1L1 DDX27 PHIP

1.28e-121975190fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOR1 USP8 TCF4 ZNF608 RSF1 ANKRD11 THRAP3 HP1BP3

3.68e-111845181154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellH1299-infected|H1299 / Cell line, Condition and Strain

SRRT NCOR1 TCF4 ANKRD11 EIF5B CCAR1 BOD1L1 HP1BP3

5.17e-111925189cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCelldroplet-Tongue-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOR1 TCF4 SEC62 ANKRD11 EIF5B PHIP

7.57e-08188516d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

NCOR1 SP100 RSF1 ANKRD11 EIF5B BOD1L1

1.06e-07199516c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell(01)_IL1RL1+-(2)_GFP_FOXI1|(01)_IL1RL1+ / shred by cell type by condition

SP100 RSF1 ANKRD11 EIF5B BOD1L1 DHX29

1.06e-07199516a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCellILEUM-non-inflamed-(3)_MNP-(3)_moDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

UPF2 ATXN2 ANKRD11 AKAP13 HECTD1

4.75e-07135515b7a792a7c0c22d8b703509f134115f0e394d7de0
ToppCellILEUM-non-inflamed-(5)_Plasma-(5)_IgM_plasma_cells|(5)_Plasma / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

UPF2 BOD1L1 RAB11FIP1 FERMT2

1.27e-0670514aa63c1b77a9fb15e75835cb3781f2d890f3fe328
ToppCelldroplet-Bladder-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCF11 NCOR1 UPF2 ANKRD11 EIF5B

2.36e-06187515663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOR1 ANKRD11 THRAP3 HP1BP3 NCBP3

2.62e-0619151560c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOR1 ANKRD11 THRAP3 HP1BP3 NCBP3

2.62e-06191515973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCellfacs-Brain_Myeloid-Hippocampus|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP8 HLF HERC2 HP1BP3 NCBP3

2.90e-06195515a1478021a3ed0e779716393124ca2a7770c433b7
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

RSF1 ANKRD11 BOD1L1 DHX29 MYEF2

3.13e-0619851576d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SP100 ANKRD11 AKAP13 BOD1L1 PHIP

3.28e-0620051512f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellILEUM-inflamed-(3)_pDC|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TCF4 ARPP21 ANKRD11 RAB11FIP1

4.90e-05176514b9f847dd55703e413f3cd815eef5724fffaf13b3
ToppCelldroplet-Marrow-nan-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOR1 HLF BOD1L1 HP1BP3

5.58e-051825141710eab3037a87609d21838be2d2d29c3bc36651
ToppCell3'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TCF4 MCTP1 HLF FERMT2

5.58e-05182514d996ceb77c83591df4cef144ca72862f31d9777f
ToppCelldroplet-Marrow-nan-3m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOR1 HLF BOD1L1 HP1BP3

5.58e-05182514e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCellnormal_Lung-B_lymphocytes-GrB-secreting_B_cells|normal_Lung / Location, Cell class and cell subclass

TCF4 ARPP21 ANKRD11 RAB11FIP1

5.70e-05183514c930b957d16f9b0904b6c424acd914532e5cc137
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

USP8 TCF4 BOD1L1 RAB11FIP1

6.46e-05189514b13f315f617840eb5143a4e8a33a657c20365c21
ToppCell10x3'2.3-week_12-13-Lymphocytic_B-B_lineage-pro_B_progenitor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TCF4 ARPP21 ZNF608 HP1BP3

6.59e-05190514f623f0bdece6002b68ac2207e99408b24a2b1194
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOR1 ANKRD11 HP1BP3 NCBP3

6.73e-0519151409db184cb90fe282a14474d7217068c58092c6f8
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

USP8 USP9X RSF1 HECTD1

7.01e-05193514abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK1 TCF4 MCTP1 ZNF608

7.15e-051945140b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_naive-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TCF4 SP100 ZNF608 SEC62

7.15e-0519451483554ba6a789750a39af58537fd7044ce20d3f02
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_naive|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TCF4 SP100 ZNF608 SEC62

7.15e-0519451456286db641cfb270e52f33989b8bf7b14d45010a
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SEC62 CIR1 EIF5B POLE3

7.15e-051945148985095f291c1b54e45f4edece49aa26e8c8b732
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TCF4 SP100 ZNF608 SEC62

7.29e-051955149355dd84350f98cb33466acdfd90a39c50c9e39f
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TCF4 UPF2 BOD1L1 RAB11FIP1

7.29e-05195514481989d2e5bd2582da3d86b0155c4d6615317067
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TCF4 UPF2 BOD1L1 RAB11FIP1

7.29e-051955146108a27523d1b93a7fbe35cb95704a5ad9071e3c
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOR1 USP9X ANKRD11 BOD1L1

7.29e-051955143e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOR1 USP9X ANKRD11 BOD1L1

7.29e-051955147796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellCOVID-19_Severe-PLT_4|World / Disease Group and Platelet Clusters

UPF2 SEC62 CIR1 DHX29

7.44e-05196514ad43efdd4d73b6615f65f06a315b33576e317473
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-IPC/newborn-38|World / Primary Cells by Cluster

TCF4 ZNF608 RSF1 PHIP

7.44e-0519651438da0751941adca650fe9b383d9f343153978eb5
ToppCellCV-Moderate-6|CV / Virus stimulation, Condition and Cluster

ANKRD11 EIF5B AKAP13 BOD1L1

7.44e-051965147bced0cc2112697593c478fa291b8ed3941fb811
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-IPC/newborn|World / Primary Cells by Cluster

TCF4 ZNF608 RSF1 PHIP

7.44e-05196514721650a08d260faf530dbd52d4e9275d27f3bac2
ToppCellCOVID-19_Mild|World / Disease group, lineage and cell class

SP100 ANKRD11 CIR1 BOD1L1

7.58e-051975145c33454b10023decd2f5ccda9229b6512659711e
ToppCellILEUM-inflamed-(3)_MNP-(3)_DC1|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

UPF2 EIF5B RAB11FIP1 MYEF2

7.58e-051975149a3d0b7f4788487d024d56bc776a2fd1149f50d5
ToppCellPBMC-Mild|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)

SP100 ANKRD11 CIR1 BOD1L1

7.73e-0519851444417089b62056269cac38d3134ff209c05b7007
ToppCellPBMC-Mild|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SP100 ANKRD11 CIR1 BOD1L1

7.73e-0519851428ef3fc4c17dcb765537b75917f7db78baa522db
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-35|World / Primary Cells by Cluster

TCF4 ZNF608 RSF1 HDAC2

7.73e-05198514de5214a85fe017eb23d4aa8af624464f062ec57e
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

RSF1 ANKRD11 EIF5B BOD1L1

7.89e-0519951461b1ed2db71b96157b92b7535d1955a4033098da
ToppCell(00)_Basal-(2)_GFP_FOXI1|(00)_Basal / shred by cell type by condition

RSF1 ANKRD11 EIF5B BOD1L1

7.89e-0519951419674e1eaeb51e4196d847cb62aa437c852951d3
ToppCell(05)_Secretory-(2)_GFP_FOXI1|(05)_Secretory / shred by cell type by condition

RSF1 ANKRD11 EIF5B BOD1L1

7.89e-05199514d72d87e1e530ed894c0ad5e7b5b2b1d6b59fa098
ToppCell(02)_MMP9/10+-(2)_GFP_FOXI1|(02)_MMP9/10+ / shred by cell type by condition

SP100 RSF1 ANKRD11 BOD1L1

7.89e-0519951418a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell(04)_Interm._basal>secr.-(2)_GFP_FOXI1|(04)_Interm._basal>secr. / shred by cell type by condition

RSF1 ANKRD11 EIF5B BOD1L1

7.89e-0519951453ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

RSF1 ANKRD11 EIF5B BOD1L1

7.89e-05199514fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCellnormal_Lung-B_lymphocytes-GrB-secreting_B_cells|B_lymphocytes / Location, Cell class and cell subclass

TCF4 ANKRD11 AKAP13 RAB11FIP1

7.89e-051995142f6074a2fd3323f258be03042f77929640ad0a75
ToppCellCOVID-19|World / Disease, condition lineage and cell class

SP100 ANKRD11 AKAP13 BOD1L1

8.04e-052005147dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCellLPS_only-Endothelial-Endothelial-Activated_Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

TCF4 MCTP1 ZNF608 FERMT2

8.04e-05200514edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

TCF4 SP100 MCTP1 ZNF608

8.04e-052005143585484c7e24e941708bee471ca607d8ccee74e6
ToppCellCOVID-19-COVID-19_Mild|COVID-19 / Disease, condition lineage and cell class

SP100 ANKRD11 CIR1 BOD1L1

8.04e-0520051462c25042086f1afd1102e0720e933c2e476468fd
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

TCF4 MCTP1 ZNF608 FERMT2

8.04e-0520051479e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCellVE|World / Condition, Cell_class and T cell subcluster

SP100 AKAP13 BOD1L1 HP1BP3

8.04e-052005148ae7cb81de3ffac5acdf3466d4b516d80cac95d3
ToppCellTCGA-Blood_and_Bone_Marrow-Primary_Blood_Derived_Cancer_-_Peripheral_Blood-Leukemia-Acute_Myeloid_Leukemia|TCGA-Blood_and_Bone_Marrow / Sample_Type by Project: Shred V9

NCOR1 ATXN2 PHIP

1.50e-04905132e324fd2d2faff2b073a2726747bd283deaa8b0a
ToppCellTCGA-Blood_and_Bone_Marrow-Primary_Blood_Derived_Cancer_-_Peripheral_Blood|TCGA-Blood_and_Bone_Marrow / Sample_Type by Project: Shred V9

NCOR1 ATXN2 PHIP

1.50e-04905136ca41b5a618be50745bf8a83d697660847d04679
ToppCellTCGA-Blood_and_Bone_Marrow-Primary_Blood_Derived_Cancer_-_Peripheral_Blood-Leukemia|TCGA-Blood_and_Bone_Marrow / Sample_Type by Project: Shred V9

NCOR1 ATXN2 PHIP

1.50e-0490513adfd1c3238f19939c9ff850524d166f549c4b4c3
ComputationalGenes in the cancer module 166.

DOCK1 NEFH RSF1 PSMD7

4.22e-0553404MODULE_166
ComputationalNeighborhood of CASP2

CCAR1 BOD1L1 THRAP3

1.31e-0427403GCM_CASP2
Diseaseintraocular pressure measurement

TCF4 ATXN2 AKAP13 BOD1L1 HERC2 FERMT2

1.91e-04509496EFO_0004695
Diseaseskin sensitivity to sun

ANKRD11 HERC2

4.54e-0419492EFO_0004795
Diseaseanxiety disorder (implicated_via_orthology)

NCOR1 HDAC2

6.11e-0422492DOID:2030 (implicated_via_orthology)
Diseaseeye measurement

ATXN2 AKAP13

9.23e-0427492EFO_0004731
Diseasemonocyte percentage of leukocytes

USP8 ATXN2 AKAP13 ZC3H18 ARHGEF11 NCBP3

1.28e-03731496EFO_0007989
Diseaseskin pigmentation measurement

ANKRD11 HERC2 MYEF2

1.54e-03137493EFO_0007009
Diseaseresponse to bronchodilator, FEV/FEC ratio

CYLC2 TCF4 SP100 MCTP1 ARHGEF38 FERMT2

1.62e-03766496EFO_0004713, GO_0097366
Diseasesleep latency

SP100 HLF

1.73e-0337492EFO_0005280
DiseaseNeoplasm of uncertain or unknown behavior of breast

NCOR1 HERC2

2.13e-0341492C0496956
DiseaseBreast adenocarcinoma

NCOR1 HERC2

2.13e-0341492C0858252
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

NCOR1 TCF4

3.02e-0349492DOID:0060037 (implicated_via_orthology)
Diseaseserum non-albumin protein measurement

USP8 SP100 ATXN2 ARHGEF38

3.03e-03361494EFO_0004568
Diseasechronotype measurement

DOCK1 CYLC1 TCF4 CIR1 R3HDM2 HP1BP3

3.28e-03882496EFO_0008328
Diseasehair colour measurement

ANKRD11 AKAP13 ZC3H18 HERC2 MYEF2

3.46e-03615495EFO_0007822
Diseaseurate measurement

TCF4 ATXN2 HLF AKAP13 R3HDM2 PAX7

3.52e-03895496EFO_0004531
Diseaseheart failure

ATXN2 HLF PHIP

3.61e-03185493EFO_0003144
Diseaseleft ventricular diastolic function measurement

MCTP1 ATXN2

3.66e-0354492EFO_0008204
DiseasePeripheral Nervous System Diseases

NEFH TCF4

3.66e-0354492C4721453
Diseaseaspartate aminotransferase measurement

USP8 ATXN2 AKAP13 R3HDM2 ZC3H18 PHIP

3.70e-03904496EFO_0004736
DiseaseAmyotrophic Lateral Sclerosis

NEFH ATXN2

4.21e-0358492C0002736
Diseasecancer

TCF4 MCTP1 ATXN2 ANKRD11

4.36e-03400494MONDO_0004992
DiseaseSjogren syndrome

ATXN2 PHIP

4.50e-0360492EFO_0000699

Protein segments in the cluster

PeptideGeneStartEntry
ERYKEKSSDKDKSEK

ANKRD11

1026

Q6UB99
KLKESEKERDSAKDK

RNF20

596

Q5VTR2
DKEKKENKKMADEDA

RNF20

686

Q5VTR2
KKEDKRKDDSKDDDE

CCAR1

846

Q8IX12
KKNDEDESLKDKLSK

ARHGEF38

296

Q9NXL2
EKDSKDKEKDKKTVN

AKAP13

1776

Q12802
KKSSNSKKEKDALED

ARHGEF11

516

O15085
DSDSKDDVKKESKKD

CYLC2

281

Q14093
DDVKKESKKDATKDA

CYLC2

286

Q14093
KKVAKKDTEKESADS

CYLC2

301

Q14093
KDTEKESADSKKDAK

CYLC2

306

Q14093
KSAAATEEEKDKKKE

DHX29

346

Q7Z478
EDKEAKSGKLEKEKE

DDX27

131

Q96GQ7
SEREKEKDKNKDKTS

ARPP21

111

Q9UBL0
SEETKKDEKDQSKEK

HP1BP3

111

Q5SSJ5
STKDVSEKEDKDKNK

R3HDM2

116

Q9Y2K5
KREDKEDKSEKAVKD

INTS13

576

Q9NVM9
DEADKKEDDGEKKAK

PAX7

171

P23759
EKKKKQDLDDEEKTA

KIN

156

O60870
DKDDKDSEKKGFINK

MCTP1

866

Q6DN14
TKKEDLNDKEKKDEE

HERC2

71

O95714
ACKQEKDDKEEKKDA

ATXN2

891

Q99700
TKSSEDKKLDDDKKD

TCF4

526

P15884
DKKKDVKKDTESTDA

CYLC1

321

P35663
SELESKESQKDEKKD

CYLC1

411

P35663
DDKKKDAKKNAESTE

CYLC1

471

P35663
DASEDKSAEKRKKDK

NCBP3

191

Q53F19
EASEQKKKDKDKKTD

POLE3

101

Q9NRF9
KKKDKDKKTDSEEQD

POLE3

106

Q9NRF9
HEDAFSKDKDKEKKL

HLF

36

Q16534
SKDKDKEKKLDDESN

HLF

41

Q16534
SQATKDSKKDKKEED

PIPSL

846

A2A3N6
DDDVKEKRKTAEKKD

PCF11

416

O94913
KTEAKAKEDDKTLSK

NEFH

976

P12036
DIKKKDENKSDDKDG

BOD1L1

1031

Q8NFC6
KGDDKKKKDTNKDEE

HECTD1

491

Q9ULT8
SQDKLDKDDLEKEKK

DOCK1

1681

Q14185
EKKDKERENEKEKSA

MAP7D1

416

Q3KQU3
KKKKLDDQSEDEALE

FERMT2

151

Q96AC1
DKKTDVKEEDKSKDN

HDAC2

456

Q92769
EDQEEKKKDSKKSKA

RSF1

991

Q96T23
NKDDTKEAKESKENK

UPF2

496

Q9HAU5
DEELKKEAKNEAKND

USP9X

291

Q93008
DSDDESVVKDKKKKS

RAB11FIP1

201

Q6WKZ4
NDESAKEEKSDLKEK

MYEF2

56

Q9P2K5
KEDKEKDKDKEKSDV

PSMD7

301

P51665
NDSEELEDKDSKSKK

EIF5B

111

O60841
KEDSKENTKEKDKID

NCOR1

541

O75376
EKKEDSEKEAKKSSK

SRRT

336

Q9BXP5
DSEEKDKSKKRKLHE

CIR1

306

Q86X95
SKEAKEKFEEKAQDK

RNF17

806

Q9BXT8
DDQDKDKAKGRKESE

THRAP3

431

Q9Y2W1
KKKVLSDSEDEEKDA

PHIP

1276

Q8WWQ0
ESGKEEDKKSKKENI

SEC62

116

Q99442
SSLFKKKKVKEDEDD

STYXL2

866

Q5VZP5
KAEKSKKKKEEEEDE

SP100

851

P23497
KKESEEDAEKKDKAE

ZNF608

1031

Q9ULD9
EDAEKKDKAEQLDSK

ZNF608

1036

Q9ULD9
EKKESEQAKKEDKET

USP8

526

P40818
EKESLEAAKEKKKED

ZC3H18

176

Q86VM9