Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity	DHX36 ERCC6 SMCHD1 KIF16B RNF213 MSH5 DNAH7 ZRANB3 DNAH1 MDN1 ATAD3A DNAH17 ABCD4 ACIN1 DDX53 ABCG2 SLFN11 DNAH5	3.06e-07	614	140	18	GO:0140657
GeneOntologyMolecularFunction	ATP hydrolysis activity	DHX36 ERCC6 SMCHD1 KIF16B RNF213 DNAH7 MDN1 ATAD3A ABCD4 ACIN1 DDX53 ABCG2 SLFN11 DNAH5	2.77e-06	441	140	14	GO:0016887
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH7 DNAH1 DNAH17 DNAH5	6.56e-06	18	140	4	GO:0008569
GeneOntologyMolecularFunction	histone H3 methyltransferase activity	SETD1A MECOM KMT2C KMT2D PRDM16	1.37e-05	44	140	5	GO:0140938
GeneOntologyMolecularFunction	histone H3K4 monomethyltransferase activity	SETD1A KMT2C KMT2D	1.84e-05	8	140	3	GO:0140945
GeneOntologyMolecularFunction	histone H3K4 trimethyltransferase activity	SETD1A KMT2C KMT2D	3.90e-05	10	140	3	GO:0140999
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH7 DNAH1 DNAH17 DNAH5	4.16e-05	28	140	4	GO:0051959
GeneOntologyMolecularFunction	protein-lysine N-methyltransferase activity	SETD1A MECOM KMT2C KMT2D PRDM16	1.15e-04	68	140	5	GO:0016279
GeneOntologyMolecularFunction	lysine N-methyltransferase activity	SETD1A MECOM KMT2C KMT2D PRDM16	1.24e-04	69	140	5	GO:0016278
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH7 DNAH1 DNAH17 DNAH5	1.28e-04	37	140	4	GO:0045505
GeneOntologyMolecularFunction	microtubule motor activity	KIF16B DNAH7 DNAH1 DNAH17 DNAH5	1.32e-04	70	140	5	GO:0003777
GeneOntologyMolecularFunction	histone methyltransferase activity	SETD1A MECOM KMT2C KMT2D PRDM16	1.42e-04	71	140	5	GO:0042054
GeneOntologyMolecularFunction	histone modifying activity	SETD1A MECOM PHF8 KDM6B KMT2C KMT2D PRKDC PRDM16	2.16e-04	229	140	8	GO:0140993
GeneOntologyMolecularFunction	histone H3K4 methyltransferase activity	SETD1A KMT2C KMT2D	3.52e-04	20	140	3	GO:0042800
GeneOntologyMolecularFunction	histone H3K27me2/H3K27me3 demethylase activity	PHF8 KDM6B	4.81e-04	5	140	2	GO:0071558
GeneOntologyMolecularFunction	phospholipid binding	WASHC2C SPTBN2 KIF16B ADGRB1 PITPNC1 DYSF WASHC2A CKMT2 MYOF SCIN ALOX15 DOC2B	4.88e-04	548	140	12	GO:0005543
GeneOntologyMolecularFunction	dioxygenase activity	PHF8 KDM6B TYW5 RSBN1L ALOX15	6.35e-04	98	140	5	GO:0051213
GeneOntologyMolecularFunction	protein methyltransferase activity	SETD1A MECOM KMT2C KMT2D PRDM16	7.96e-04	103	140	5	GO:0008276
GeneOntologyMolecularFunction	N-methyltransferase activity	SETD1A MECOM KMT2C KMT2D PRDM16	8.68e-04	105	140	5	GO:0008170
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	DHX36 ERCC6 SMCHD1 KIF16B RNF213 DNAH7 MDN1 ATAD3A ABCD4 ACIN1 DDX53 ABCG2 SLFN11 DNAH5	1.11e-03	775	140	14	GO:0017111
GeneOntologyMolecularFunction	phosphatidylinositol-3,5-bisphosphate binding	WASHC2C KIF16B WASHC2A	1.31e-03	31	140	3	GO:0080025
GeneOntologyMolecularFunction	histone H3K9 monomethyltransferase activity	MECOM PRDM16	1.33e-03	8	140	2	GO:0140948
GeneOntologyMolecularFunction	cytoskeletal motor activity	KIF16B DNAH7 DNAH1 DNAH17 DNAH5	1.46e-03	118	140	5	GO:0003774
GeneOntologyMolecularFunction	phosphatidylinositol bisphosphate binding	WASHC2C KIF16B WASHC2A SCIN ALOX15	1.64e-03	121	140	5	GO:1902936
GeneOntologyMolecularFunction	phosphatidylinositol-3,4-bisphosphate binding	WASHC2C KIF16B WASHC2A	1.87e-03	35	140	3	GO:0043325
GeneOntologyMolecularFunction	vitamin transmembrane transporter activity	GC ABCD4 ABCG2	2.03e-03	36	140	3	GO:0090482
GeneOntologyMolecularFunction	retromer complex binding	WASHC2C WASHC2A	2.12e-03	10	140	2	GO:1905394
GeneOntologyMolecularFunction	histone H3K9me2 methyltransferase activity	MECOM PRDM16	2.12e-03	10	140	2	GO:0140947
GeneOntologyMolecularFunction	pyrophosphatase activity	DHX36 ERCC6 SMCHD1 KIF16B RNF213 DNAH7 MDN1 ATAD3A ABCD4 ACIN1 DDX53 ABCG2 SLFN11 DNAH5	2.33e-03	839	140	14	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	DHX36 ERCC6 SMCHD1 KIF16B RNF213 DNAH7 MDN1 ATAD3A ABCD4 ACIN1 DDX53 ABCG2 SLFN11 DNAH5	2.35e-03	840	140	14	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	DHX36 ERCC6 SMCHD1 KIF16B RNF213 DNAH7 MDN1 ATAD3A ABCD4 ACIN1 DDX53 ABCG2 SLFN11 DNAH5	2.35e-03	840	140	14	GO:0016818
GeneOntologyCellularComponent	axonemal dynein complex	DNAH7 DNAH1 DNAH17 DNAH5	2.19e-05	25	140	4	GO:0005858
GeneOntologyCellularComponent	MLL3/4 complex	KDM6B KMT2C KMT2D	6.19e-05	12	140	3	GO:0044666
GeneOntologyCellularComponent	plasma membrane bounded cell projection cytoplasm	DZIP1L DNAH7 MADD DNAH1 RP1L1 DNAH17 STAU2 DNAH5 BRWD1	2.92e-04	317	140	9	GO:0032838
GeneOntologyCellularComponent	dynein complex	DNAH7 DNAH1 DNAH17 DNAH5	4.70e-04	54	140	4	GO:0030286
GeneOntologyCellularComponent	axoneme	DZIP1L DNAH7 DNAH1 RP1L1 DNAH17 DNAH5 BRWD1	4.99e-04	207	140	7	GO:0005930
GeneOntologyCellularComponent	ciliary plasm	DZIP1L DNAH7 DNAH1 RP1L1 DNAH17 DNAH5 BRWD1	5.13e-04	208	140	7	GO:0097014
GeneOntologyCellularComponent	cell-cell junction	AKAP6 ANK3 FBF1 SPTBN2 SH3KBP1 ADGRB1 PANX1 TRIM29 ADAM10 ITGB1 FRMD6 EPHA5	6.36e-04	591	140	12	GO:0005911
GeneOntologyCellularComponent	cytoplasmic region	DZIP1L DNAH7 MADD DNAH1 RP1L1 DNAH17 STAU2 DNAH5 BRWD1	7.31e-04	360	140	9	GO:0099568
GeneOntologyCellularComponent	microtubule	MDM1 KIF16B DYSF DNAH7 DNAH1 STIM1 RP1L1 DNAH17 STAU2 DNAH5 WDR44	9.40e-04	533	140	11	GO:0005874
MousePheno	abnormal circulating creatine kinase level	ZMPSTE24 SPTBN2 PITPNC1 TRIM29 DYSF STIM1	1.75e-05	65	118	6	MP:0010089
MousePheno	abnormal creatine kinase level	ZMPSTE24 SPTBN2 PITPNC1 TRIM29 DYSF STIM1	1.91e-05	66	118	6	MP:0020279
Domain	Evi1/Prdm16	MECOM PRDM16	5.26e-05	2	136	2	IPR030413
Domain	FAM21	WASHC2C WASHC2A	5.26e-05	2	136	2	IPR027308
Domain	AAA	RNF213 DNAH7 MDN1 ATAD3A ABCD4 ABCG2 DNAH5	8.92e-05	144	136	7	SM00382
Domain	AAA+_ATPase	RNF213 DNAH7 MDN1 ATAD3A ABCD4 ABCG2 DNAH5	8.92e-05	144	136	7	IPR003593
Domain	-	DHX36 ERCC6 RNF213 MSH5 DNAH7 ZRANB3 EHD4 DNAH1 MDN1 ATAD3A MTHFD1 ABCD4 DDX53 ABCG2 SLFN11 DNAH5	1.07e-04	746	136	16	3.40.50.300
Domain	Dynein_heavy_chain_D4_dom	DNAH7 DNAH1 DNAH5	1.30e-04	14	136	3	IPR024317
Domain	Dynein_HC_stalk	DNAH7 DNAH1 DNAH5	1.30e-04	14	136	3	IPR024743
Domain	Dynein_heavy_dom-2	DNAH7 DNAH1 DNAH5	1.30e-04	14	136	3	IPR013602
Domain	DHC_N2	DNAH7 DNAH1 DNAH5	1.30e-04	14	136	3	PF08393
Domain	ATPase_dyneun-rel_AAA	DNAH1 MDN1 DNAH5	1.30e-04	14	136	3	IPR011704
Domain	MT	DNAH7 DNAH1 DNAH5	1.30e-04	14	136	3	PF12777
Domain	AAA_8	DNAH7 DNAH1 DNAH5	1.30e-04	14	136	3	PF12780
Domain	AAA_5	DNAH1 MDN1 DNAH5	1.30e-04	14	136	3	PF07728
Domain	P-loop_NTPase	DHX36 ERCC6 KIF16B RNF213 MSH5 DNAH7 ZRANB3 EHD4 DNAH1 MDN1 ATAD3A MTHFD1 ABCD4 DDX53 ABCG2 SLFN11 DNAH5	1.46e-04	848	136	17	IPR027417
Domain	FerA	DYSF MYOF	1.57e-04	3	136	2	SM01200
Domain	Ferlin_A-domain	DYSF MYOF	1.57e-04	3	136	2	IPR012560
Domain	FerA	DYSF MYOF	1.57e-04	3	136	2	PF08165
Domain	CAP-ZIP_m	WASHC2C WASHC2A	1.57e-04	3	136	2	PF15255
Domain	FAM21/CAPZIP	WASHC2C WASHC2A	1.57e-04	3	136	2	IPR029341
Domain	DHC_fam	DNAH7 DNAH1 DNAH5	1.61e-04	15	136	3	IPR026983
Domain	Dynein_heavy	DNAH7 DNAH1 DNAH5	1.61e-04	15	136	3	PF03028
Domain	Dynein_heavy_dom	DNAH7 DNAH1 DNAH5	1.61e-04	15	136	3	IPR004273
Domain	Post-SET_dom	SETD1A KMT2C KMT2D	1.97e-04	16	136	3	IPR003616
Domain	PostSET	SETD1A KMT2C KMT2D	1.97e-04	16	136	3	SM00508
Domain	POST_SET	SETD1A KMT2C KMT2D	1.97e-04	16	136	3	PS50868
Domain	FAM47	FAM47C FAM47B	3.13e-04	4	136	2	PF14642
Domain	DysFC	DYSF MYOF	3.13e-04	4	136	2	SM00694
Domain	DysFN	DYSF MYOF	3.13e-04	4	136	2	SM00693
Domain	FAM47	FAM47C FAM47B	3.13e-04	4	136	2	IPR032743
Domain	Peroxin/Ferlin	DYSF MYOF	3.13e-04	4	136	2	IPR006614
Domain	SET	SETD1A KMT2C KMT2D PRDM16	3.46e-04	46	136	4	SM00317
Domain	SET_dom	SETD1A KMT2C KMT2D PRDM16	4.78e-04	50	136	4	IPR001214
Domain	SET	SETD1A KMT2C KMT2D PRDM16	4.78e-04	50	136	4	PS50280
Domain	FerI	DYSF MYOF	5.19e-04	5	136	2	SM01202
Domain	FerB	DYSF MYOF	5.19e-04	5	136	2	SM01201
Domain	FYrich_C	KMT2C KMT2D	5.19e-04	5	136	2	IPR003889
Domain	FYrich_N	KMT2C KMT2D	5.19e-04	5	136	2	IPR003888
Domain	Ferlin_B-domain	DYSF MYOF	5.19e-04	5	136	2	IPR012561
Domain	FYRC	KMT2C KMT2D	5.19e-04	5	136	2	SM00542
Domain	FYRN	KMT2C KMT2D	5.19e-04	5	136	2	SM00541
Domain	Ferlin_C	DYSF MYOF	5.19e-04	5	136	2	PF16165
Domain	Ferlin_C	DYSF MYOF	5.19e-04	5	136	2	IPR032362
Domain	FerIin_dom	DYSF MYOF	5.19e-04	5	136	2	IPR012968
Domain	FerI	DYSF MYOF	5.19e-04	5	136	2	PF08151
Domain	FerB	DYSF MYOF	5.19e-04	5	136	2	PF08150
Domain	FYRN	KMT2C KMT2D	5.19e-04	5	136	2	PF05964
Domain	FYRC	KMT2C KMT2D	5.19e-04	5	136	2	PF05965
Domain	FYRC	KMT2C KMT2D	5.19e-04	5	136	2	PS51543
Domain	FYRN	KMT2C KMT2D	5.19e-04	5	136	2	PS51542
Domain	JMJC	PHF8 KDM6B TYW5	1.60e-03	32	136	3	PS51184
Domain	JmjC_dom	PHF8 KDM6B TYW5	1.60e-03	32	136	3	IPR003347
Domain	JmjC	PHF8 KDM6B TYW5	1.76e-03	33	136	3	SM00558
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT	DNAH7 DNAH1 DNAH17 DNAH5	4.15e-05	27	103	4	M47755
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	AKAP6 FAM234B ZMPSTE24 WASHC2C SLC7A13 ANK3 RPS6KB1 DZIP1L MSH5 WASHC2A ITGB1 ZRANB3 MADD KMT2C MTHFD1 ALDH1L2 KCNJ3 ACIN1 METTL17 LMBRD1 BRWD1	3.52e-09	1084	142	21	11544199
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	MON2 SLC12A6 WASHC2C WFS1 KIF16B GPAT3 WASHC2A ITGB1 MADD STIM1 PPP1R15B SLC35A2 SCIN	1.70e-07	504	142	13	34432599
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH7 DNAH1 DNAH17 DNAH5	2.58e-07	14	142	4	9373155
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	SETD1A ANK3 SMCHD1 SPTBN2 PHF8 CSDE1 KMT2C UBE2O KMT2D ACIN1 PRKDC RSBN1L WDR44	4.47e-07	549	142	13	38280479
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MON2 ATMIN SETD1A PANX1 KDM6B DYSF WASHC2A MADD C6orf132 KMT2C MYOF KMT2D MDN1 ZNRF3 PPP1R15B SLC35A2 PRKDC PRDM16	6.49e-07	1105	142	18	35748872
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	MON2 BCL9L DLGAP2 WASHC2C ANK3 WFS1 SH3KBP1 ADGRB1 TRIM29 WASHC2A MADD STIM1 CSDE1 UBE2O ATAD3A MTHFD1 KCNJ3 STAU2	1.00e-06	1139	142	18	36417873
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	DHX36 SETD1A SMCHD1 RNF213 PHF8 INTS8 EHD4 KMT2D ACIN1 RSBN1L	1.52e-06	341	142	10	32971831
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	MON2 CUL4A ERCC6 ATXN7L1 FBF1 MECOM RNF213 PHF8 INTS10 ARHGEF33 ZNRF3 CCNB3 TYW5 SLFN11 PRDM16 RSBN1L BRWD1	3.34e-06	1116	142	17	31753913
Pubmed	The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.	SETD1A KMT2C KMT2D	3.68e-06	8	142	3	22266653
Pubmed	Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases.	SETD1A KMT2C KMT2D	3.68e-06	8	142	3	23130995
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	AKAP6 SETD1A SPTBN2 KDM6B MADD MDN1	4.55e-06	104	142	6	9205841
Pubmed	Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.	SETD1A KMT2C KMT2D	5.50e-06	9	142	3	22665483
Pubmed	Human transcription factor protein interaction networks.	DHX36 BCL9L SETD1A ZMPSTE24 ATXN7L1 SMCHD1 SH3KBP1 MECOM ZNF217 PHF8 WASHC2A KMT2C UBE2O KMT2D ATAD3A STAU2 NOC4L PRDM16 MRPL11	6.08e-06	1429	142	19	35140242
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	CUL4A DHX36 CSDE1 MYOF HARS2 MDN1 MTHFD1 MOB3B PRKDC BRWD1	6.12e-06	399	142	10	37536630
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	MON2 ATMIN WASHC2C PHF8 WASHC2A MADD CSDE1 AKAP9 FBXO28 ACIN1	7.27e-06	407	142	10	12693553
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	CUL4A ATMIN SLC12A6 SGSM1 ANK3 ATXN7L1 MYT1 RPS6KB1 EVC RNF213 MSH5 INTS8 ITGB1 DNAH1 CSDE1 KMT2C ATAD3A KCNJ3 RASGEF1C	1.09e-05	1489	142	19	28611215
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	DHX36 KIF16B GPAT3 RNF213 ITGB1 EHD4 STIM1 HARS2 MDN1 AKAP9 ATAD3A ALDH1L2 FBXO28 PPP1R15B STAU2 NOC4L METTL17 MRPL11 WDR44	1.16e-05	1496	142	19	32877691
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	SETD1A SGSM1 WASHC2C FBF1 ADGRB1 NUTM2D IRF7 TGM6 TRIM29 WASHC2A MDN1 AKAP9 SLC16A6 ATAD3A DNAH17 STAU2 C10orf120	1.35e-05	1242	142	17	30973865
Pubmed	Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes.	SETD1A KMT2C KMT2D	1.43e-05	12	142	3	27563068
Pubmed	Calcium-sensitive phospholipid binding properties of normal and mutant ferlin C2 domains.	DYSF MYOF	1.66e-05	2	142	2	11959863
Pubmed	Deletion of 12/15-lipoxygenase alters macrophage and islet function in NOD-Alox15(null) mice, leading to protection against type 1 diabetes development.	PRKDC ALOX15	1.66e-05	2	142	2	23437231
Pubmed	Loss of dysferlin or myoferlin results in differential defects in excitation-contraction coupling in mouse skeletal muscle.	DYSF MYOF	1.66e-05	2	142	2	34354129
Pubmed	The lysosomal protein ABCD4 can transport vitamin B12 across liposomal membranes in vitro.	ABCD4 LMBRD1	1.66e-05	2	142	2	33845046
Pubmed	A novel gene, MEL1, mapped to 1p36.3 is highly homologous to the MDS1/EVI1 gene and is transcriptionally activated in t(1;3)(p36;q21)-positive leukemia cells.	MECOM PRDM16	1.66e-05	2	142	2	11050005
Pubmed	KMT2C/D COMPASS complex-associated diseases [KCDCOM-ADs]: an emerging class of congenital regulopathies.	KMT2C KMT2D	1.66e-05	2	142	2	31924266
Pubmed	Cytoplasmic relaxation of active Eph controls ephrin shedding by ADAM10.	ADAM10 EFNA3	1.66e-05	2	142	2	19823572
Pubmed	High expression of EVI1 and MEL1 is a compelling poor prognostic marker of pediatric AML.	MECOM PRDM16	1.66e-05	2	142	2	25567132
Pubmed	Control of HIV replication in astrocytes by a family of highly conserved host proteins with a common Rev-interacting domain (Risp).	WASHC2C WASHC2A	1.66e-05	2	142	2	20827171
Pubmed	Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability.	KMT2C KMT2D	1.66e-05	2	142	2	28967912
Pubmed	FAM21 is critical for TLR2/CLEC4E-mediated dendritic cell function against Candida albicans.	WASHC2C WASHC2A	1.66e-05	2	142	2	36717248
Pubmed	CSB interacts with SNM1A and promotes DNA interstrand crosslink processing.	ERCC6 DCLRE1A	1.66e-05	2	142	2	25505141
Pubmed	Clinical or ATPase domain mutations in ABCD4 disrupt the interaction between the vitamin B12-trafficking proteins ABCD4 and LMBD1.	ABCD4 LMBRD1	1.66e-05	2	142	2	28572511
Pubmed	Mutant collagen COL11A1 enhances cancerous invasion.	COL11A1 ITGB1	1.66e-05	2	142	2	34584216
Pubmed	Association of KMT2C/D loss-of-function variants with response to immune checkpoint blockades in colorectal cancer.	KMT2C KMT2D	1.66e-05	2	142	2	36601880
Pubmed	Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation.	KMT2C KMT2D	1.66e-05	2	142	2	28483418
Pubmed	Partial dysferlin reconstitution by adult murine mesoangioblasts is sufficient for full functional recovery in a murine model of dysferlinopathy.	DYSF PRKDC	1.66e-05	2	142	2	21364666
Pubmed	The MLL3/4 H3K4 methyltransferase complex in establishing an active enhancer landscape.	KMT2C KMT2D	1.66e-05	2	142	2	34156443
Pubmed	Structural Basis for the Distinct Membrane Binding Activity of the Homologous C2A Domains of Myoferlin and Dysferlin.	DYSF MYOF	1.66e-05	2	142	2	31004665
Pubmed	Identification of a novel Rev-interacting cellular protein.	WASHC2C WASHC2A	1.66e-05	2	142	2	15847701
Pubmed	A role for the Eph ligand ephrin-A3 in entorhino-hippocampal axon targeting.	EFNA3 EPHA5	1.66e-05	2	142	2	10516308
Pubmed	Reduced Expression of Histone Methyltransferases KMT2C and KMT2D Correlates with Improved Outcome in Pancreatic Ductal Adenocarcinoma.	KMT2C KMT2D	1.66e-05	2	142	2	27280393
Pubmed	Leukemia induction after a single retroviral vector insertion in Evi1 or Prdm16.	MECOM PRDM16	1.66e-05	2	142	2	18496560
Pubmed	While dysferlin and myoferlin are coexpressed in the human placenta, only dysferlin expression is responsive to trophoblast fusion in model systems.	DYSF MYOF	1.66e-05	2	142	2	19228595
Pubmed	Solution structure of the inner DysF domain of myoferlin and implications for limb girdle muscular dystrophy type 2b.	DYSF MYOF	1.66e-05	2	142	2	18495154
Pubmed	Loss of MLL3/4 decouples enhancer H3K4 monomethylation, H3K27 acetylation, and gene activation during embryonic stem cell differentiation.	KMT2C KMT2D	1.66e-05	2	142	2	36869380
Pubmed	Translocation of the ABC transporter ABCD4 from the endoplasmic reticulum to lysosomes requires the escort protein LMBD1.	ABCD4 LMBRD1	1.66e-05	2	142	2	27456980
Pubmed	15-lipoxygenase-1 activates tumor suppressor p53 independent of enzymatic activity.	PRKDC ALOX15	1.66e-05	2	142	2	18785202
Pubmed	Absence of T and B lymphocytes modulates dystrophic features in dysferlin deficient animal model.	DYSF PRKDC	1.66e-05	2	142	2	22465227
Pubmed	Crucial roles of mixed-lineage leukemia 3 and 4 as epigenetic switches of the hepatic circadian clock controlling bile acid homeostasis in mice.	KMT2C KMT2D	1.66e-05	2	142	2	25346535
Pubmed	Insertional mutagenesis identifies genes that promote the immortalization of primary bone marrow progenitor cells.	MECOM PRDM16	1.66e-05	2	142	2	16109773
Pubmed	Global landscape of HIV-human protein complexes.	CUL4A ICAM2 RNF213 CSDE1 HARS2 UBE2O AKAP9 ATAD3A PRKDC MRPL11	1.97e-05	457	142	10	22190034
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	ANK3 ADGRB1 PANX1 ITGB1 EHD4 MYOF FRMD6 SLC35A2 WDR44	2.64e-05	377	142	9	38117590
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	MON2 ANK3 SPTBN2 RNF213 PHF8 ITGB1 MADD EHD4 STIM1 KMT2D AKAP9 NOC4L SLFN11 CDC25A SCIN	2.72e-05	1049	142	15	27880917
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	SLC12A6 ZMPSTE24 WFS1 SMCHD1 RNF213 INTS8 CSDE1 MYOF HARS2 MDN1 SLC16A6 ZNRF3 MTHFD1 SLC35A2 PRKDC	3.10e-05	1061	142	15	33845483
Pubmed	Unpackaging the genetics of mammalian fertility: strategies to identify the "reproductive genome".	DNAH1 AKAP9 BRWD1	3.59e-05	16	142	3	29878059
Pubmed	H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation.	SETD1A KMT2C KMT2D	3.59e-05	16	142	3	24368734
Pubmed	A High-Density Map for Navigating the Human Polycomb Complexome.	SETD1A SMCHD1 ZNF217 ARG1 KMT2C UBE2O KMT2D ATAD3A FBXO28 MRPL11	3.88e-05	495	142	10	27705803
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	ERCC6 ANK3 SPTBN2 GC DYSF KMT2C MDN1 MTHFD1 METTL17 RSBN1L	4.01e-05	497	142	10	36774506
Pubmed	KIAA1530 protein is recruited by Cockayne syndrome complementation group protein A (CSA) to participate in transcription-coupled repair (TCR).	CUL4A SETD1A ERCC6	4.35e-05	17	142	3	22902626
Pubmed	Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.	SETD1A PHF8 KDM6B KMT2C	4.89e-05	49	142	4	34368113
Pubmed	Type I collagen promotes tumor progression of integrin β1 positive gastric cancer through a BCL9L/β-catenin signaling pathway.	BCL9L ITGB1	4.95e-05	3	142	2	34319913
Pubmed	Tetraspanin CD82 Associates with Trafficking Vesicle in Muscle Cells and Binds to Dysferlin and Myoferlin.	DYSF MYOF	4.95e-05	3	142	2	37434585
Pubmed	Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription.	KMT2C KMT2D	4.95e-05	3	142	2	23932714
Pubmed	The C2 domains of otoferlin, dysferlin, and myoferlin alter the packing of lipid bilayers.	DYSF MYOF	4.95e-05	3	142	2	23859474
Pubmed	The conserved and divergent roles of Prdm3 and Prdm16 in zebrafish and mouse craniofacial development.	MECOM PRDM16	4.95e-05	3	142	2	32044379
Pubmed	Mutations of PTCH1, MLL2, and MLL3 are not frequent events in hepatoblastoma.	KMT2C KMT2D	4.95e-05	3	142	2	22183980
Pubmed	HOXC6 Is transcriptionally regulated via coordination of MLL histone methylase and estrogen receptor in an estrogen environment.	KMT2C KMT2D	4.95e-05	3	142	2	21683083
Pubmed	sp2 -Iminosugar α-glucosidase inhibitor 1-C-octyl-2-oxa-3-oxocastanospermine specifically affected breast cancer cell migration through Stim1, β1-integrin, and FAK signaling pathways.	ITGB1 STIM1	4.95e-05	3	142	2	28145580
Pubmed	Prdm3 and Prdm16 cooperatively maintain hematopoiesis and clonogenic potential.	MECOM PRDM16	4.95e-05	3	142	2	32437910
Pubmed	Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity.	PHF8 KDM6B	4.95e-05	3	142	2	27133168
Pubmed	FerA is a Membrane-Associating Four-Helix Bundle Domain in the Ferlin Family of Membrane-Fusion Proteins.	DYSF MYOF	4.95e-05	3	142	2	30026467
Pubmed	Purification and interaction analyses of two human lysosomal vitamin B12 transporters: LMBD1 and ABCD4.	ABCD4 LMBRD1	4.95e-05	3	142	2	25535791
Pubmed	Integrin α11β1 regulates cancer stromal stiffness and promotes tumorigenicity and metastasis in non-small cell lung cancer.	ITGB1 PRKDC	4.95e-05	3	142	2	26148229
Pubmed	EphrinA/EphA-induced ectodomain shedding of neural cell adhesion molecule regulates growth cone repulsion through ADAM10 metalloprotease.	ADAM10 EPHA5	4.95e-05	3	142	2	24117969
Pubmed	A non-canonical role for Rgnef in promoting integrin-stimulated focal adhesion kinase activation.	ARHGEF28 ITGB1	4.95e-05	3	142	2	24006257
Pubmed	Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.	MECOM PRDM16	4.95e-05	3	142	2	16582916
Pubmed	Dysferlin and myoferlin regulate transverse tubule formation and glycerol sensitivity.	DYSF MYOF	4.95e-05	3	142	2	24177035
Pubmed	PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.	SETD1A KMT2C KMT2D	5.20e-05	18	142	3	17500065
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	DHX36 ERCC6 SMCHD1 SPTBN2 TRIM29 ARG1 CSDE1 MYOF HARS2 ATAD3A MTHFD1 STAU2 ACIN1 PRKDC MRPL11 RSBN1L	5.84e-05	1257	142	16	36526897
Pubmed	FBF1 deficiency promotes beiging and healthy expansion of white adipose tissue.	FBF1 AKAP9 PRDM16	6.15e-05	19	142	3	34348145
Pubmed	Accelerating functional gene discovery in osteoarthritis.	WASHC2C WASHC2A DNAH17 STAU2	6.68e-05	53	142	4	33473114
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	WASHC2C SMCHD1 RNF213 EHD4 MDN1 MTHFD1 ACIN1 PRKDC	7.02e-05	332	142	8	32786267
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	DHX36 ERCC6 SMCHD1 CENPU PHF8 CSDE1 MDN1 STAU2 ACIN1 NOC4L PRKDC METTL17	7.02e-05	759	142	12	35915203
Pubmed	Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy.	SETD1A KMT2C KMT2D	7.22e-05	20	142	3	29785026
Pubmed	Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.	KDM6B KMT2C KMT2D	8.40e-05	21	142	3	27626377
Pubmed	New nomenclature for chromatin-modifying enzymes.	SETD1A KDM6B KMT2C KMT2D	8.89e-05	57	142	4	18022353
Pubmed	The interactome of metabolic enzyme carbonic anhydrase IX reveals novel roles in tumor cell migration and invadopodia/MMP14-mediated invasion.	WFS1 GPAT3 PANX1 ITGB1 STIM1 SLC35A2	8.93e-05	176	142	6	28692057
Pubmed	Structural basis for activity regulation of MLL family methyltransferases.	SETD1A KMT2C KMT2D	9.69e-05	22	142	3	26886794
Pubmed	Crucial roles for interactions between MLL3/4 and INI1 in nuclear receptor transactivation.	KMT2C KMT2D	9.88e-05	4	142	2	19221051
Pubmed	Cancer gene mutation frequencies for the U.S. population.	KMT2C KMT2D	9.88e-05	4	142	2	34645806
Pubmed	Silencing of β1 integrin regulates airway remodeling by regulating the transcription of SOCE‑associated genes in asthmatic mice.	ITGB1 STIM1	9.88e-05	4	142	2	28656279
Pubmed	Mutations in dynein genes in patients affected by isolated non-syndromic asthenozoospermia.	DNAH1 DNAH5	9.88e-05	4	142	2	18492703
Pubmed	Transcriptional program of ciliated epithelial cells reveals new cilium and centrosome components and links to human disease.	MDM1 CFAP157	9.88e-05	4	142	2	23300604
Pubmed	A novel role for acinus and MCM2 as host-specific signaling enhancers of DNA-damage-induced apoptosis in association with viral protein gp70.	ACIN1 PRKDC	9.88e-05	4	142	2	19058849
Pubmed	Common variations in 4p locus are related to male completed suicide.	WFS1 EVC	9.88e-05	4	142	2	19115052
Pubmed	MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.	KMT2C KMT2D	9.88e-05	4	142	2	28398509
Pubmed	A subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity.	KMT2C KMT2D	9.88e-05	4	142	2	23129768
Pubmed	AHNAK, a novel component of the dysferlin protein complex, redistributes to the cytoplasm with dysferlin during skeletal muscle regeneration.	DYSF MYOF	9.88e-05	4	142	2	17185750
Pubmed	The MLL3/MLL4 branches of the COMPASS family function as major histone H3K4 monomethylases at enhancers.	KMT2C KMT2D	9.88e-05	4	142	2	24081332
Pubmed	Interaction network of human early embryonic transcription factors.	BCL9L SETD1A NAB2 MECOM ZNF217 KMT2C KMT2D PRDM16	1.03e-04	351	142	8	38297188
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	SETD1A MECOM KMT2C KMT2D PRDM16	9.36e-07	34	96	5	487
GeneFamily	Dyneins, axonemal	DNAH7 DNAH1 DNAH17 DNAH5	1.68e-06	17	96	4	536
GeneFamily	Ferlin family	DYSF MYOF	4.13e-04	6	96	2	828
GeneFamily	WASH complex	WASHC2C WASHC2A	4.13e-04	6	96	2	1331
GeneFamily	Integrator complex	INTS8 INTS10	2.80e-03	15	96	2	1366
Coexpression	DESCARTES_FETAL_LIVER_MESOTHELIAL_CELLS	DLGAP2 COL11A1 DNAH7 AMIGO1 C6orf132 CNGB3 PTPRQ OSR1 CNTN3 ALOX15	8.46e-06	313	142	10	M40228
Coexpression	RB_P130_DN.V1_DN	ZMPSTE24 KIF16B CSDE1 AKAP9 TYW5 FBXO28 ABCG2	9.63e-06	136	142	7	M2803
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	OVCH2 ANK3 SPTBN2 MECOM KCNJ3 SCIN PRDM16 FYB2 DOC2B	9.92e-09	188	142	9	e30a4ddac0da8cdcf621d98e28e3895cd9307e7a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	OVCH2 ANK3 SPTBN2 MECOM KCNJ3 SCIN PRDM16 FYB2 DOC2B	1.09e-08	190	142	9	11d3c31167ea71809b4cc3757a0c6ea54a448602
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	OVCH2 ANK3 SPTBN2 MECOM KCNJ3 SCIN PRDM16 FYB2 EPHA5	1.09e-08	190	142	9	b7f8c2bb9459f1d7c1690069dd5a25a81a57cc84
ToppCell	Control_saline-Epithelial_airway\|Control_saline / Treatment groups by lineage, cell group, cell type	DNAH7 C6orf132 DNAH1 ARG1 USP2 SCIN DNAH5 FYB2 CFAP157	1.56e-08	198	142	9	e6863238e022ecfb6a8e3f4b7661b376e92c5d8f
ToppCell	Control_saline-Epithelial_airway-airway_epithelial\|Control_saline / Treatment groups by lineage, cell group, cell type	DNAH7 C6orf132 DNAH1 ARG1 USP2 SCIN DNAH5 FYB2 CFAP157	1.56e-08	198	142	9	e7aa42e5fbd42c68f50cda4a8f3aa464c862c007
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	OVCH2 SPTBN2 MECOM KCNJ3 SCIN FYB2 EPHA5 DOC2B	1.73e-07	189	142	8	bfc76a72b600d641c8fe58346e5d8986c34f3981
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	OVCH2 SPTBN2 MECOM KCNJ3 SCIN PRDM16 FYB2 DOC2B	1.88e-07	191	142	8	96b78b4e819ea6052334bfcbc7abbf35897df885
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 SPTBN2 MECOM KCNJ3 SCIN PRDM16 FYB2 DOC2B	1.96e-07	192	142	8	40f44ac4ab673ee6156abdd2074a60b9de3281ad
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	AKAP6 ANK3 DZIP1L DNAH7 DNAH5 FYB2 ALOX15 CFAP157	2.04e-07	193	142	8	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF28 EVC MECOM RNF213 DNAH7 MYOF MOB3B DNAH5	2.12e-07	194	142	8	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF28 ANK3 EVC MECOM DNAH7 ZNRF3 KCNJ3 PRDM16	2.12e-07	194	142	8	93c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF28 ANK3 MECOM ZNRF3 KCNJ3 SCIN PRDM16 FYB2	2.29e-07	196	142	8	c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF28 ANK3 EVC MECOM DNAH7 ZNRF3 KCNJ3 PRDM16	2.29e-07	196	142	8	eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 MECOM CKMT2 RP1L1 MOB3B FYB2 LGI1	7.38e-07	157	142	7	2c5295043611bac7dfa4aef2146681bce4a33a8f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SPTBN2 MECOM CKMT2 SCIN PRDM16 FYB2 DOC2B	8.74e-07	161	142	7	176a4a72bb4892932da3c834d1fea5e211847f92
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SGSM1 SPTBN2 MECOM CKMT2 SCIN PRDM16 FYB2	1.03e-06	165	142	7	9bd332e5ede759a00a47728ea5558c215efdd77a
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AKAP6 DZIP1L DNAH7 SCIN DNAH5 FYB2 CFAP157	1.59e-06	176	142	7	dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 SPTBN2 STIM1 KCNJ3 SCIN PRDM16 FYB2	1.65e-06	177	142	7	f35b04c3557ebbdeba37dec54c8f45880eafb422
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 SPTBN2 MECOM KCNJ3 MOB3B PRDM16 FYB2	1.91e-06	181	142	7	aa233b652921848af2257cc3687a7a09c3acfb67
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 SPTBN2 MECOM KCNJ3 PRDM16 FYB2 DOC2B	1.91e-06	181	142	7	b7c85fbef3c06d5dc32a2a58f8d3dfabf1d79d9f
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 SPTBN2 MECOM KCNJ3 SCIN PRDM16 FYB2	2.06e-06	183	142	7	b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	OVCH2 SPTBN2 MECOM KCNJ3 PRDM16 FYB2 DOC2B	2.06e-06	183	142	7	d340ab5a77e8d819a1dfb4ca3e9a4b9bc988923c
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	INPP5D ICAM2 DYSF EHD4 SLC16A6 RP1L1 ABCG2	2.37e-06	187	142	7	50d5730e2cd4951d3ad0641fc81ae9f6ddabafe7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SPTBN2 MECOM KCNJ3 SCIN PRDM16 FYB2 DOC2B	2.37e-06	187	142	7	f6217d0dd425eac76900b44a4e48f45475f3ac36
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 SPTBN2 MECOM KCNJ3 SCIN PRDM16 FYB2	2.37e-06	187	142	7	2d17408b3b5f09d135084fd7ccce98e6b5ca632b
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 SPTBN2 MECOM SCIN PRDM16 FYB2 DOC2B	2.46e-06	188	142	7	58ccb31cdf43167872ef0fc737e6f9c51ee2e060
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF28 SPTBN2 MECOM CKMT2 SCIN PRDM16 FYB2	2.46e-06	188	142	7	e751cff2ac8fbc1487766c1871fcc5d1005286b0
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	OVCH2 ANK3 SPTBN2 MECOM KCNJ3 PRDM16 FYB2	2.55e-06	189	142	7	3a295c215b5c18e7c673f92b7af5be523421682c
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 SPTBN2 MECOM KCNJ3 PRDM16 FYB2 DOC2B	2.55e-06	189	142	7	c9565e962a13a7713056ec3dbb1b67d24f9889c7
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	MON2 ANK3 SMCHD1 RNF213 PITPNC1 KMT2C PPP1R15B	2.82e-06	192	142	7	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	COVID-19-kidney-CD-PC\|kidney / Disease (COVID-19 only), tissue and cell type	ANK3 SPTBN2 MECOM KCNJ3 SCIN PRDM16 FYB2	2.92e-06	193	142	7	738689d009e4b118d7ce3171a207294b95cbe78b
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 SPTBN2 MECOM KCNJ3 SCIN FYB2 DOC2B	3.02e-06	194	142	7	be869e186386d03ebb670971dd24fa656b4b0edf
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 SPTBN2 MECOM KCNJ3 SCIN FYB2 DOC2B	3.02e-06	194	142	7	4d6c9b016e3a0641954a8ea10c97d1cd76fadd9f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF28 ANK3 MECOM DNAH7 ZNRF3 KCNJ3 SCIN	3.02e-06	194	142	7	5eaaa81f4b2535f983c424aaef00077089526a5c
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF28 ANK3 MECOM DNAH7 ZNRF3 KCNJ3 PRDM16	3.13e-06	195	142	7	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AKAP6 DZIP1L DNAH7 AKAP9 DNAH5 FYB2 CFAP157	3.35e-06	197	142	7	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	LPS_only-Epithelial_airway-airway_epithelial\|LPS_only / Treatment groups by lineage, cell group, cell type	DNAH7 C6orf132 DNAH1 ARG1 A2ML1 DNAH5 CFAP157	3.46e-06	198	142	7	e035380578c01b0243bfef29ca9b50cc17cce771
ToppCell	LPS_only-Epithelial_airway\|LPS_only / Treatment groups by lineage, cell group, cell type	DNAH7 C6orf132 DNAH1 ARG1 A2ML1 DNAH5 CFAP157	3.46e-06	198	142	7	ba090210392e001a3f7bdf09371b3f0e0c8c7ef3
ToppCell	BAL-Mild-Epithelial-Epithelial\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MECOM TRIM29 DNAH7 DNAH5 FYB2 ALOX15 CFAP157	3.58e-06	199	142	7	1ee4010d8557564e25e8ee00b914c2dfd9037838
ToppCell	BAL-Mild-Epithelial-Epithelial\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	MECOM TRIM29 DNAH7 DNAH5 FYB2 ALOX15 CFAP157	3.58e-06	199	142	7	1df69c0cb5f759f6a2152521842506a75bb95cae
ToppCell	Mild-Epithelial-Epithelial-\|Mild / Condition, Lineage, Cell class and cell subclass	MECOM TRIM29 DNAH7 DNAH5 FYB2 ALOX15 CFAP157	3.58e-06	199	142	7	81115bbd2c10bfdd38376d2075f03a59c31870d2
ToppCell	BAL-Mild-Epithelial\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MECOM TRIM29 DNAH7 DNAH5 FYB2 ALOX15 CFAP157	3.58e-06	199	142	7	74087b4b5e567310fc4ac58fb267ff651a180680
ToppCell	BAL-Mild-Epithelial\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	MECOM TRIM29 DNAH7 DNAH5 FYB2 ALOX15 CFAP157	3.58e-06	199	142	7	00b5ce099c50a5e1786ce2b3a06ee0931a8205a4
ToppCell	Mild-Epithelial\|Mild / Condition, Lineage, Cell class and cell subclass	MECOM TRIM29 DNAH7 DNAH5 FYB2 ALOX15 CFAP157	3.58e-06	199	142	7	ec5fff80e2a8a94fbaf1fdcc6d45c8d7c6252e18
ToppCell	Mild-Epithelial-Epithelial\|Mild / Condition, Lineage, Cell class and cell subclass	MECOM TRIM29 DNAH7 DNAH5 FYB2 ALOX15 CFAP157	3.58e-06	199	142	7	91308b255783ad4029e5575028c18d7550832c51
ToppCell	Mild_COVID-19-Epithelial\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	MECOM TRIM29 DNAH7 DNAH5 FYB2 ALOX15 CFAP157	3.58e-06	199	142	7	72689bda7476930887ae007682fcab27f956f050
ToppCell	control\|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ARHGEF28 ANK3 TRIM29 C6orf132 MYOF AKAP9 ALOX15	3.70e-06	200	142	7	97f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCell	LPS_IL1RA-Epithelial_airway-airway_epithelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TRIM29 DNAH7 ARG1 A2ML1 SCIN DNAH5 CFAP157	3.70e-06	200	142	7	cf191104484bfb2b9f87de416b9453135f8833c1
ToppCell	LPS_IL1RA_TNF-Epithelial_airway-airway_epithelial\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	DNAH7 DNAH1 ARG1 A2ML1 SCIN DNAH5 CFAP157	3.70e-06	200	142	7	da12821e8a0657869ca0f75d351cce2d7605a505
ToppCell	LPS_IL1RA-Epithelial_airway\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TRIM29 DNAH7 ARG1 A2ML1 SCIN DNAH5 CFAP157	3.70e-06	200	142	7	a5ae33dd4dc1ff6e1a1eec22c4d523d5ab657607
ToppCell	NS-control\|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ARHGEF28 ANK3 TRIM29 C6orf132 MYOF AKAP9 ALOX15	3.70e-06	200	142	7	ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCell	LPS_IL1RA_TNF-Epithelial_airway\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	DNAH7 DNAH1 ARG1 A2ML1 SCIN DNAH5 CFAP157	3.70e-06	200	142	7	72c1d9eeaed4b3ee6b6c602e8aa29efc2e8744eb
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL11A1 MYT1 CNGB3 PTPRQ CNTN3 EPHA5	7.21e-06	145	142	6	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF28 SPTBN2 GPAT3 KCNJ3 SCIN FYB2	1.45e-05	164	142	6	d847d509bb1791638032ade6755d8164586b5bd5
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF28 SPTBN2 GPAT3 KCNJ3 SCIN FYB2	1.56e-05	166	142	6	6fe8db8d45177a78605681f22e04fa8d0594f2df
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SPTBN2 GPAT3 MECOM SCIN PRDM16 FYB2	1.61e-05	167	142	6	edc5f04584b44f99ff9a62bbe0dab6fc044fb334
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF28 SPTBN2 GPAT3 STIM1 SCIN FYB2	1.72e-05	169	142	6	4b3a7b4a497178799b6b2f0b744f5fb752cee31a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF28 SPTBN2 GPAT3 STIM1 SCIN FYB2	1.72e-05	169	142	6	a4fd646b9bf87225131fca530bd6b52df9eaf489
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-9\|TCGA-Bladder / Sample_Type by Project: Shred V9	SLC12A6 BCL9L ANK3 TRIM29 FRMD6 RP1L1	1.84e-05	171	142	6	adbcfa4bf6bc1c604535a24435924cdb091e2dd7
ToppCell	P15-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL11A1 ERCC6 ANK3 FBF1 MSH5 TESK2	2.17e-05	176	142	6	792f414f5092aba14260b8e16378e793a822498e
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 SPTBN2 KCNJ3 PRDM16 FYB2 DOC2B	2.38e-05	179	142	6	d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 SPTBN2 MECOM PRDM16 FYB2 DOC2B	2.46e-05	180	142	6	023ec0b080c8a5cd0f36e83c6b17d4be3c01edb5
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ANK3 MECOM GSTA4 CNTN3 DNAH5 PRDM16	2.78e-05	184	142	6	102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BTBD6 ERCC6 ZRANB3 DNAH1 FRMD6 DNAH5	2.87e-05	185	142	6	05bc89a566b0db90ae06506e067190a4739a0974
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	MON2 SMCHD1 RNF213 ADAM10 KMT2D PRKDC	2.87e-05	185	142	6	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	AKAP6 DZIP1L DNAH7 USP2 DNAH5 CFAP157	2.87e-05	185	142	6	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SPTBN2 MECOM CKMT2 SCIN PRDM16 FYB2	2.87e-05	185	142	6	3d73b3e0bceb192257e5cfbe64b7ccb379b6e22d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SPTBN2 MECOM CKMT2 KCNJ3 PRDM16 FYB2	2.96e-05	186	142	6	08632045d499e61dd96ff29a5a9a208afe58dc58
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF28 SPTBN2 MECOM CKMT2 PRDM16 FYB2	2.96e-05	186	142	6	a6ef5d5944af5689b5f27bef89cd05645eedbe50
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 SPTBN2 MECOM KCNJ3 PRDM16 FYB2	3.05e-05	187	142	6	e3095455d2f255854f339f6b05fa87852af0700f
ToppCell	LA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	AKAP6 ANK3 GPAT3 DYSF KCNJ3 EPHA5	3.14e-05	188	142	6	6d249fe92d51a19da19ec14bb2262d394255d577
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ICAM2 MECOM DYSF EHD4 ABCG2 CDC25A	3.14e-05	188	142	6	5d166d9e71632edd059ff0a9f66f8763f259d40a
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DLGAP2 COL11A1 PTPRQ FYB2 ALOX15 EPHA5	3.14e-05	188	142	6	9655a4c47b644a870017d349b99063e17dbae572
ToppCell	COVID-19-kidney-CD-PC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ANK3 SPTBN2 MECOM KCNJ3 SCIN FYB2	3.14e-05	188	142	6	8f9996c3f3b27efaaae8960a66af77412de9c7ef
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	OVCH2 MECOM CKMT2 KCNJ3 SCIN PRDM16	3.14e-05	188	142	6	4154f4787483c7e076e87a187733a9f666742c3d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SPTBN2 MECOM KCNJ3 SCIN PRDM16 FYB2	3.23e-05	189	142	6	8ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCell	COVID-19-lung-Secretory\|lung / Disease (COVID-19 only), tissue and cell type	ARHGEF28 ANK3 MECOM CNTN3 DNAH5 FYB2	3.23e-05	189	142	6	84d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCell	PBMC-Mild-cDC_12\|Mild / Compartment, Disease Groups and Clusters	CENPU MECOM MTHFD1 ABCG2 PRKDC CDC25A	3.23e-05	189	142	6	946c95d2ecc36b241f58e8c4ad6455fe47c762fa
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	OVCH2 ANK3 MECOM ZNRF3 PTPRQ PRDM16	3.33e-05	190	142	6	8aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCell	LA-03._Atrial_Cardiomyocyte\|LA / Chamber and Cluster_Paper	AKAP6 ANK3 GPAT3 DYSF CKMT2 KCNJ3	3.43e-05	191	142	6	5d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	MON2 SMCHD1 RNF213 ADAM10 PPP1R15B PRKDC	3.43e-05	191	142	6	9454f642c3621370fa23640b631301346b300950
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	OVCH2 SPTBN2 MECOM SCIN FYB2 DOC2B	3.43e-05	191	142	6	7235a4d1601c88a2c8af571a2c04ab56d32f1b9a
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	OVCH2 ANK3 MECOM ZNRF3 PTPRQ PRDM16	3.43e-05	191	142	6	ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCell	COVID-19-kidney-CNT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ANK3 SPTBN2 MECOM KCNJ3 SCIN FYB2	3.53e-05	192	142	6	760c6b9628de9693034b00c5025c5c4df94bb2e8
ToppCell	LAM-Epithelial-AirwayEpi\|LAM / Condition, Lineage and Cell class	TRIM29 DNAH7 DNAH5 FYB2 ALOX15 CFAP157	3.53e-05	192	142	6	7404fc65be3b7bd09447725b43fa31819004dfee
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SPTBN2 MECOM CKMT2 SCIN PRDM16 FYB2	3.53e-05	192	142	6	f7e7491426bbd6ed29a465b58bf67acb93dbb90a
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SPTBN2 MECOM SCIN PRDM16 FYB2 DOC2B	3.53e-05	192	142	6	fd08ae787e936cfdb1ab8f19b0fd63005b462709
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL11A1 ANK3 MECOM GSTA4 ZNRF3 DNAH5	3.53e-05	192	142	6	cc9911e182a289779a2612bc213daae5607689e7
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SPTBN2 MECOM SCIN PRDM16 FYB2 DOC2B	3.53e-05	192	142	6	bae236c9f1fac77bce28d0a9cf090100d391ff77
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	OVCH2 SPTBN2 MECOM SCIN FYB2 DOC2B	3.74e-05	194	142	6	d602a0cdb69cd5a3e9ef61ddbab8d920557dd73e
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_12\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GPAT3 CENPU MTHFD1 SDHAF4 ALOX15	3.83e-05	118	142	5	f0f40a0165156e3fc1584480b473b0e84e10d2cc
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	INPP5D ICAM2 MECOM DYSF EHD4 DOC2B	3.85e-05	195	142	6	752a100297c26732e12bbbf3ab27a2bd4f5ea06d
ToppCell	Control_saline-Epithelial_airway-airway_epithelial-Ciliated\|Control_saline / Treatment groups by lineage, cell group, cell type	DNAH7 DNAH1 USP2 DNAH5 FYB2 CFAP157	3.85e-05	195	142	6	60067b5359174f0d1a8b5748bfc0690762e9e740
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF28 ANK3 EVC DNAH7 ZNRF3 KCNJ3	3.96e-05	196	142	6	6ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_12\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GPAT3 CENPU MTHFD1 SDHAF4 ALOX15	3.99e-05	119	142	5	a6b359e7aafcc197f53eb5e19c3a905bc09497bb
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	DHX36 ANK3 SMCHD1 RNF213 KMT2C AKAP9	4.08e-05	197	142	6	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DZIP1L DNAH7 AKAP9 DNAH5 ALOX15 CFAP157	4.08e-05	197	142	6	22c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DZIP1L DNAH7 AKAP9 DNAH5 ALOX15 CFAP157	4.08e-05	197	142	6	3bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DZIP1L DNAH7 AKAP9 DNAH5 ALOX15 CFAP157	4.08e-05	197	142	6	87db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCell	COVID-19_Mild\|World / Disease group, lineage and cell class	DHX36 SMCHD1 RNF213 IRF7 KDM6B KMT2C	4.08e-05	197	142	6	5c33454b10023decd2f5ccda9229b6512659711e
Disease	3,5-dichloro-2,6-dihydroxybenzoic acid measurement	ZRANB3 ABCG2	2.11e-05	2	136	2	EFO_0801054
Disease	Kleefstra syndrome 2 (implicated_via_orthology)	KMT2C KMT2D	2.11e-05	2	136	2	DOID:0080598 (implicated_via_orthology)
Disease	Achromatopsia 3	COL11A1 CNGB3	2.11e-05	2	136	2	C1849792
Disease	Massive Hepatic Necrosis	PANX1 PRKDC	2.11e-05	2	136	2	C0001364
Disease	Methylmalonic aciduria and homocystinuria	ABCD4 LMBRD1	2.09e-04	5	136	2	cv:CN293516
Disease	Progeria	ZMPSTE24 ANK3	2.09e-04	5	136	2	C0033300
Disease	breast carcinoma (is_marker_for)	KDM6B KMT2D ABCG2 CDC25A	2.49e-04	66	136	4	DOID:3459 (is_marker_for)
Disease	primary ciliary dyskinesia (is_implicated_in)	DNAH7 BRWD1	3.13e-04	6	136	2	DOID:9562 (is_implicated_in)
Disease	Colorectal Carcinoma	AKAP6 ERCC6 RPS6KB1 SPTBN2 ZNF217 KMT2C AKAP9 CCNB3 ABCD4 ACIN1 ABCG2	4.23e-04	702	136	11	C0009402
Disease	limb-girdle muscular dystrophy (implicated_via_orthology)	DYSF MYOF	4.36e-04	7	136	2	DOID:11724 (implicated_via_orthology)
Disease	anemia (phenotype), response to ribavirin	IRF7 DNAH17	7.43e-04	9	136	2	EFO_0004272, GO_1901559
Disease	Disorders of Intracellular Cobalamin Metabolism	ABCD4 LMBRD1	9.26e-04	10	136	2	cv:CN043592
Disease	ornithine measurement	GPAT3 MECOM ARG1	1.10e-03	44	136	3	EFO_0009776
Disease	Microphthalmos	ERCC6 KMT2D	1.13e-03	11	136	2	C0026010
Disease	autosomal recessive polycystic kidney disease (biomarker_via_orthology)	PANX1 CDC25A	1.13e-03	11	136	2	DOID:0110861 (biomarker_via_orthology)
Disease	Intellectual Disability	AKAP6 SETD1A KDM6B CSDE1 KMT2C SLC35A2 ACIN1 ZMYM6	1.13e-03	447	136	8	C3714756
Disease	amino acid measurement	DLGAP2 ARHGEF28 MYT1 TGM6 DNAH7 RP1L1 STAU2 ABCG2 PRKDC ALOX15	1.22e-03	678	136	10	EFO_0005134
Disease	Malignant neoplasm of breast	AKAP6 COL11A1 ERCC6 KIF16B MECOM TRIM29 DYSF ADAM10 KMT2D RPRD1A AKAP9 SLC35A2 ABCG2	1.42e-03	1074	136	13	C0006142
Disease	Fulminant Hepatic Failure with Cerebral Edema	GC PRKDC	1.59e-03	13	136	2	C0751197
Disease	Hepatic Stupor	GC PRKDC	1.59e-03	13	136	2	C0751198
Disease	Hepatic Encephalopathy	GC PRKDC	1.59e-03	13	136	2	C0019151
Disease	Hepatic Coma	GC PRKDC	1.59e-03	13	136	2	C0019147
Disease	sphingomyelin measurement	FAM234B KIF16B MADD ZNRF3 FBXO28 ALOX15	1.88e-03	278	136	6	EFO_0010118
Disease	Uveal Melanoma	TRIM29 KCNJ3 DDX53	1.90e-03	53	136	3	EFO_1000616
Disease	Diffuse Large B-Cell Lymphoma	RPS6KB1 KMT2D ABCG2	2.11e-03	55	136	3	C0079744
Disease	Situs ambiguus	BCL9L DNAH5	2.13e-03	15	136	2	C0266642
Disease	autosomal recessive polycystic kidney disease (implicated_via_orthology)	DZIP1L CDC25A	2.43e-03	16	136	2	DOID:0110861 (implicated_via_orthology)
Disease	attention deficit hyperactivity disorder, autism spectrum disorder, intelligence	AKAP6 COL11A1 DYSF AMIGO1 KMT2D KCNJ3 BRWD1	2.54e-03	398	136	7	EFO_0003756, EFO_0003888, EFO_0004337
Disease	platelet component distribution width	CUL4A MYT1 KIF16B MECOM STIM1 UBE2O TESK2 PRDM16 SDHAF4 BRWD1	2.68e-03	755	136	10	EFO_0007984
Disease	mean platelet volume	CUL4A SLC12A6 SH3KBP1 KIF16B MECOM ZNF217 STIM1 FBXO28 TESK2 IL21 PRDM16 SDHAF4	2.74e-03	1020	136	12	EFO_0004584
Disease	allergic rhinitis	ZNF217 IL21 PRDM16 ALOX15	3.40e-03	133	136	4	EFO_0005854
Disease	macrophage inflammatory protein 1b measurement	ANK3 SLFN11 CDC25A SCIN	3.68e-03	136	136	4	EFO_0008219
Disease	glomerulonephritis (biomarker_via_orthology)	ITGB1 ALOX15	3.79e-03	20	136	2	DOID:2921 (biomarker_via_orthology)
Disease	citrulline measurement	MECOM RP1L1	3.79e-03	20	136	2	EFO_0009777
Disease	lung non-small cell carcinoma (is_implicated_in)	ERCC6 MSH5 KMT2C KMT2D	3.98e-03	139	136	4	DOID:3908 (is_implicated_in)
Disease	metabolite measurement	SETD1A COL11A1 ANK3 ZRANB3 ARG1 MYOF ABCG2 LGI1	4.53e-03	560	136	8	EFO_0004725
Disease	otitis media (implicated_via_orthology)	MECOM DNAH5	4.59e-03	22	136	2	DOID:10754 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
PPAKLLDDLFRKTKA	ACIN1	1206	Q9UKV3
TDSFPKKIKGLLRAV	AKAP9	2936	Q99996
SRFPLELVKEGAKLP	AMIGO1	171	Q86WK6
GTLKRPSLPEEEKLK	ADGRB1	1251	O14514
DGPLARLKKAIFSPE	ADAM10	651	O14672
TNKPRLDFPLTKRKG	BTBD6	371	Q96KE9
LAAEKDGTPVFKLPK	ALDH1L2	66	Q3SY69
PPGTGKTLFAKKLAL	ATAD3A	401	Q9NVI7
LPGKRELPVAIKTLK	EPHA5	696	P54756
KGRSDTLIKPVLVKP	A2ML1	891	A8K2U0
VKLKSGFLPCRKPVE	ABCG2	46	Q9UNQ0
KAKPLSRSLKEFPRA	ARHGEF33	701	A8MVX0
KKPGRKLRPISDDSE	CENPU	126	Q71F23
FVIPKELPFGDKDTK	CSDE1	291	O75534
PKGKFPITREKSLDL	DLGAP2	996	Q9P1A6
APSSDKPLIKDLSLK	ABCD4	396	O14678
PGSLKRLEKFSLPEV	CFAP157	501	Q5JU67
TLDRKVPSPEAFLGK	ATXN7L1	31	Q9ULK2
SFLLKELKGKIPDVP	ARG1	146	P05089
KPTTGKELSFKEPLA	CCNB3	936	Q8WWL7
LEFPPKKLFGNKDER	KIF16B	1241	Q96L93
LVLFKPETRGLKDPE	NR2E3	326	Q9Y5X4
CKELPGPKESRRTAK	INTS8	701	Q75QN2
PKKDSDSFKIRPLGF	ITGB1	436	P05556
KPKFRKGSDLKLLPC	INTS10	541	Q9NVR2
PFDLTTKRKDEKPLT	MECOM	741	Q03112
KDKTFRPKRKFEPGT	MOB3B	11	Q86TA1
LDRSFDILKKSKPPS	ARHGEF28	341	Q8N1W1
KPLSRSKLPEKFGTG	DZIP1L	741	Q8IYY4
DPVDKFSKLRPLISK	ERCC6	706	P0DP91
KLGKKLRSDEPLIDP	FAM47C	946	Q5HY64
LIPKPGRDTTKKENF	nan	516	O00370
RATKLKKPILLEGSP	MDN1	1741	Q9NU22
EFLKKLGTSLKPDPV	KMT2C	4381	Q8NEZ4
KGAREKATPFPSLKV	MADD	871	Q8WXG6
RSFSPKSPLELGEKL	NAB2	156	Q15742
IKSKSKDGRPLPARD	LMBRD1	251	Q9NUN5
KLRSLSEGPPKELKI	KDM6B	1091	O15054
PEDFSILFTVKPKKG	COL11A1	96	P12107
SRALKLPGKKSPDLG	FAM234B	6	A2RU67
KLGKKLRSDEPLIDP	FAM47B	556	Q8NA70
RNFKGLSPVKEPKLR	MDM1	236	Q8TC05
PPFTGENRKKTIDKI	RPS6KB1	291	P23443
GPEPKAVLKKFREEL	ALOX15	616	P16050
ALVVDPKKPFRKLSR	EHD4	116	Q9H223
GRPKEKSLVLVKLEP	IRF7	441	Q92985
LRALSLECKKKFPPV	MON2	21	Q7Z3U7
LLKEPTEPKFKGLRL	PANX1	16	Q96RD7
LDVTKLSPEKKPTRG	OSR1	151	Q8TAX0
KTKPTPIYDATGKLL	PTPRQ	1791	Q9UMZ3
KEEGATKKAPSRLPL	C6orf132	326	Q5T0Z8
KFEILPDGLPSARKL	FRMD6	286	Q96NE9
PFLPREGLKKIPSEK	DNAH1	2081	Q9P2D7
SKLDKRRKGVFGPPL	DNAH1	2271	Q9P2D7
IPTIKRFLEPGSKKK	GSTA4	191	O15217
VNPTIRKDLKTGPKF	ATMIN	116	O43313
TPGDTPIRKKEELLF	FBF1	191	Q8TES7
PIDSKIFFIKGPAKE	KLRF1	191	Q9NZS2
EFIGETRVPLKKLKP	DOC2B	226	Q14184
PKLEKSISGTSPKRE	EFNA3	206	P52797
LKFRLDASDKPLKVG	DNAH17	1616	Q9UFH2
ADKKKLPILIFPEGT	GPAT3	291	Q53EU6
SFKDPFVIPLGKEKI	DHX36	726	Q9H2U1
PVKPGDLKKRIESLI	CUL4A	726	Q13619
SKLDKRRKGVFGPPL	DNAH7	2021	Q8WXX0
FDEKIVPILKRKLPG	FBXO28	211	Q9NVF7
KPPKEFLERFKSLLQ	IL21	131	Q9HBE4
VPPFSSLKGKVKRDR	BCL9L	101	Q86UU0
RLSFLKEPKTTKGLP	ANK3	1411	Q12955
TSPKRELAKDLPKSG	C17orf80	146	Q9BSJ5
ESLKFSPRPLKFTEK	BRWD1	306	Q9NSI6
DDLKSGEKRLIPKPT	DDX53	206	Q86TM3
GEKRLIPKPTCRFKD	DDX53	211	Q86TM3
ESKLLPAKRGLLEKP	EVC	916	P57679
PPKRKEEKLLGESAL	DCLRE1A	566	Q6PJP8
KPCKETQIPLKLRFG	CYP3A7	466	P24462
VDGTVFPKSPKELLK	CES3	316	Q6UWW8
PLFDKFTPLPEGKLK	ZMPSTE24	221	O75844
YLPKGEIIEKPSAKS	SLC12A6	451	Q9UHW9
QSLKKPKLPEGRFDA	SDHAF4	46	Q5VUM1
DVTGKIKLPKDSFRP	DYSF	906	O75923
DLVLKGKEKSPLDPR	METTL17	311	Q9H7H0
RDLKKKGPEPVPLEF	NOC4L	481	Q9BVI4
DISRSCKPKPIGKLA	MTHFD1	321	P11586
IKGLFPDITRPFKKS	C4orf51	101	C9J302
SKIKLRKFSGVLEIP	CNTN3	271	Q9P232
SPILEGFLKKRSPQE	DNAH5	2406	Q8TE73
FLLKKPIVPTDGKRV	CDC25A	411	P30304
VRIPKLSKDPRFSKI	CKMT2	331	P17540
PSEKKAPLLDFSILK	SLC16A6	276	O15403
DLIRSGKPIKPVKDL	MSH5	776	O43196
AKKRPLFGSLSPAEK	NUTM2D	746	Q5VT03
RTKDIKEGIPLPTKI	MRPL11	56	Q9Y3B7
PPGSLSAKKVRTEEK	RSBN1L	36	Q6PCB5
KPPVTFAEKGELRKS	TRIM29	116	Q14134
EKPNFIIKTPKGTRD	HARS2	51	P49590
GRPLPSKAIKFSVKE	SMCHD1	806	A6NHR9
GKEPVHLLSLFKDKP	SCIN	476	Q9Y6U3
SFIPKAGKKIELPTL	OVCH2	541	Q7RTZ1
GLTPEEPRKKLETKG	FYB2	176	Q5VWT5
VKAEPKSPRDALKVG	PRDM16	751	Q9HAZ2
GDIFKDKPIKLRPRS	SH3KBP1	216	Q96B97
DFLPVEKTIGKKLPA	SH3KBP1	236	Q96B97
LVVKFGETLPKLKPI	INPP5D	776	Q92835
FLKTKRKPKILEEGP	SLFN11	151	Q7Z7L1
VRPKKLAVEPKGSLE	ICAM2	31	P13598
VTLGEPKLLKRFFKT	TEX45	356	Q8NA69
YSPPDLKLELKAKGS	PPP1R15B	151	Q5SWA1
DSSPGRKKFPLKIFK	STIM1	666	Q13586
GALRLPSFKVKRKEP	SETD1A	886	O15047
ITEPFLPKLLTKVKG	SLC35A2	381	P78381
QPTLPKRGLFLKEET	AKAP6	386	Q13023
FPPKEETPKLFKTLL	CNGB3	666	Q9NQW8
FLPAKKPERSIAGLT	C10orf120	266	Q5SQS8
LKIPLFLVGKPGSSK	RNF213	2761	Q63HN8
RTVEKPPKFTEKGNL	SPTBN2	351	O15020
LFFKKRPKTIVKAGP	STAU2	286	Q9NUL3
TPAKKITFLKRGDPR	RP1L1	31	Q8IWN7
KRKGPEFTKDFAPVI	RPRD1A	71	Q96P16
PVLDKARVRKFGPKL	RASGEF1C	96	Q8N431
EERKLLSLLKSFGPP	SPATA31D1	91	Q6ZQQ2
QKKSLPDSPLRFDGL	TRIM15	321	Q9C019
EFLSVPKDRPRKKSA	PITPNC1	286	Q9UKF7
GPPKSFRELKEAIKI	UBE2O	806	Q9C0C9
KLAERLKAKLPDATP	GC	421	P02774
PPRKRKSELEFETLK	WDR44	256	Q5JSH3
TLPSGEAKPRKTLKE	WASHC2C	311	Q9Y4E1
LIAGELKKPRTTIPK	SLC7A13	226	Q8TCU3
KVGKNFPPAEDLSRK	SGSM1	76	Q2NKQ1
APLKSVGPDFGKKRL	PRKDC	2691	P78527
TLPSGEAKPRKTLKE	WASHC2A	311	Q641Q2
AELDSPPSKKKRLGF	ZMYM6	726	O95789
LDPKPCLTVLGKAKR	ZNRF3	131	Q9ULT6
DKIGKEFIRATPSKP	ZNF830	136	Q96NB3
EFGEPLPKRLKSSVV	ZNF217	911	O75362
LGKEKATLIIRPKFP	PHF8	661	Q9UPP1
PKLRPSFVEIGKTLE	TESK2	296	Q96S53
ASLLEKEKLGFKPVP	USP2	41	O75604
LLEPATKPSIAGKFK	TGM6	486	O95932
IRKQFPLLKGDIKFP	TYW5	121	A2RUC4
LITKESRPRDPFTKK	ZRANB3	856	Q5FWF4
GKSPEDLPLRLKVVK	WFS1	276	O76024
PPFGESRKALEVKKE	KMT2D	2276	O14686
KLLKSRQTPEGEFLP	KCNJ3	231	P48549
LSALLLTEGKKPAKP	LGI1	26	O95970
LATFLEKTPPDKKLE	MYOF	541	Q9NZM1
GEPGKAAKPLDTVRK	MYT1	411	Q01538
RPKLDLGFKEGQTIK	NECAP1	146	Q8NC96