Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	L-ornithine transmembrane transporter activity	SLC7A1 SLC7A2 SLC7A3	1.30e-07	5	48	3	GO:0000064
GeneOntologyMolecularFunction	L-lysine transmembrane transporter activity	SLC7A1 SLC7A2 SLC7A3	1.08e-06	9	48	3	GO:0015189
GeneOntologyMolecularFunction	L-arginine transmembrane transporter activity	SLC7A1 SLC7A2 SLC7A3	3.67e-06	13	48	3	GO:0061459
GeneOntologyMolecularFunction	amino acid transmembrane transporter activity	SLC6A1 SLC7A1 SLC7A2 SLC7A3 SLC7A14	5.23e-06	105	48	5	GO:0015171
GeneOntologyMolecularFunction	carboxylic acid transmembrane transporter activity	SLC6A1 SLC7A1 SLC7A2 SLC7A3 SLC26A4 SLC7A14	9.85e-06	207	48	6	GO:0046943
GeneOntologyMolecularFunction	organic acid transmembrane transporter activity	SLC6A1 SLC7A1 SLC7A2 SLC7A3 SLC26A4 SLC7A14	1.01e-05	208	48	6	GO:0005342
GeneOntologyMolecularFunction	basic amino acid transmembrane transporter activity	SLC7A1 SLC7A2 SLC7A3	1.44e-05	20	48	3	GO:0015174
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	SLC6A1 SLC7A1 SLC7A2 SLC7A3 SLC26A4 SLC7A14	6.93e-05	293	48	6	GO:0008514
GeneOntologyMolecularFunction	gamma-aminobutyric acid transmembrane transporter activity	SLC6A1 SLC7A14	2.02e-04	9	48	2	GO:0015185
GeneOntologyMolecularFunction	L-amino acid transmembrane transporter activity	SLC7A1 SLC7A2 SLC7A3	6.64e-04	71	48	3	GO:0015179
GeneOntologyMolecularFunction	organic cation transmembrane transporter activity	SLC7A1 SLC7A2 SLC7A3	1.05e-03	83	48	3	GO:0015101
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	MOK ERN1 PIK3C2A HIPK2 ROCK1 ROS1 EIF2AK3	1.43e-03	709	48	7	GO:0016773
GeneOntologyMolecularFunction	protein serine kinase activity	MOK ERN1 HIPK2 ROCK1 EIF2AK3	1.74e-03	363	48	5	GO:0106310
GeneOntologyMolecularFunction	kinase activity	MOK ERN1 PIK3C2A HIPK2 ROCK1 ROS1 EIF2AK3	2.19e-03	764	48	7	GO:0016301
GeneOntologyMolecularFunction	complement binding	CR2 CFB	2.68e-03	32	48	2	GO:0001848
GeneOntologyMolecularFunction	protein kinase activity	MOK ERN1 HIPK2 ROCK1 ROS1 EIF2AK3	3.01e-03	600	48	6	GO:0004672
GeneOntologyMolecularFunction	chloride transmembrane transporter activity	SLC6A1 SLC26A4 GABRA2	3.37e-03	125	48	3	GO:0015108
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	MOK ERN1 HIPK2 ROCK1 EIF2AK3	4.23e-03	446	48	5	GO:0004674
GeneOntologyBiologicalProcess	L-ornithine transmembrane transport	SLC7A1 SLC7A2 SLC7A3	2.83e-07	6	51	3	GO:1903352
GeneOntologyBiologicalProcess	ornithine transport	SLC7A1 SLC7A2 SLC7A3	4.95e-07	7	51	3	GO:0015822
GeneOntologyBiologicalProcess	L-arginine import across plasma membrane	SLC7A1 SLC7A2 SLC7A3	7.91e-07	8	51	3	GO:0097638
GeneOntologyBiologicalProcess	L-lysine transmembrane transport	SLC7A1 SLC7A2 SLC7A3	1.69e-06	10	51	3	GO:1903401
GeneOntologyBiologicalProcess	L-lysine transport	SLC7A1 SLC7A2 SLC7A3	1.69e-06	10	51	3	GO:1902022
GeneOntologyBiologicalProcess	L-arginine transmembrane transport	SLC7A1 SLC7A2 SLC7A3	6.35e-06	15	51	3	GO:1903826
GeneOntologyBiologicalProcess	basic amino acid transmembrane transport	SLC7A1 SLC7A2 SLC7A3	1.34e-05	19	51	3	GO:1990822
GeneOntologyBiologicalProcess	lysine transport	SLC7A1 SLC7A3	1.80e-05	3	51	2	GO:0015819
GeneOntologyBiologicalProcess	basic amino acid transport	SLC7A1 SLC7A2 SLC7A3	2.12e-05	22	51	3	GO:0015802
GeneOntologyBiologicalProcess	transport across blood-brain barrier	SLC6A1 SLC7A1 SLC7A2 SLC7A3	6.34e-05	87	51	4	GO:0150104
GeneOntologyBiologicalProcess	carboxylic acid transport	SLC6A1 SLC7A1 SLC7A2 SLC7A3 ACACB SLC26A4 SLC7A14	6.34e-05	410	51	7	GO:0046942
GeneOntologyBiologicalProcess	organic acid transport	SLC6A1 SLC7A1 SLC7A2 SLC7A3 ACACB SLC26A4 SLC7A14	6.54e-05	412	51	7	GO:0015849
GeneOntologyBiologicalProcess	vascular transport	SLC6A1 SLC7A1 SLC7A2 SLC7A3	6.63e-05	88	51	4	GO:0010232
GeneOntologyBiologicalProcess	gamma-aminobutyric acid import	SLC6A1 SLC7A14	8.93e-05	6	51	2	GO:0051939
GeneOntologyBiologicalProcess	amino acid transport	SLC6A1 SLC7A1 SLC7A2 SLC7A3 SLC7A14	1.18e-04	195	51	5	GO:0006865
GeneOntologyBiologicalProcess	vascular process in circulatory system	SLC6A1 SLC7A1 SLC7A2 SLC7A3 PIK3C2A ROCK1	1.97e-04	344	51	6	GO:0003018
GeneOntologyBiologicalProcess	amino acid transmembrane transport	SLC7A1 SLC7A2 SLC7A3 SLC7A14	2.20e-04	120	51	4	GO:0003333
GeneOntologyBiologicalProcess	organic anion transport	SLC6A1 SLC7A1 SLC7A2 SLC7A3 ACACB SLC26A4 SLC7A14	2.60e-04	515	51	7	GO:0015711
GeneOntologyBiologicalProcess	amino acid import across plasma membrane	SLC7A1 SLC7A2 SLC7A3	3.99e-04	58	51	3	GO:0089718
Domain	CAT3	SLC7A1 SLC7A2 SLC7A3 SLC7A14	2.09e-10	5	49	4	IPR015606
Domain	AA_permease_C	SLC7A1 SLC7A2 SLC7A3 SLC7A14	2.09e-10	5	49	4	PF13906
Domain	CAT_C	SLC7A1 SLC7A2 SLC7A3 SLC7A14	2.09e-10	5	49	4	IPR029485
Domain	Cat_AA_permease	SLC7A1 SLC7A2 SLC7A3	1.70e-08	3	49	3	IPR004755
Domain	AA_permease_2	SLC7A1 SLC7A2 SLC7A3 SLC7A14	2.94e-08	13	49	4	PF13520
Domain	AA/rel_permease1	SLC7A1 SLC7A2 SLC7A3 SLC7A14	2.94e-08	13	49	4	IPR002293
Domain	AA-permease/SLC12A_dom	SLC7A1 SLC7A2 SLC7A3 SLC7A14	2.95e-07	22	49	4	IPR004841
Domain	AA_permease	SLC7A1 SLC7A2 SLC7A3 SLC7A14	2.95e-07	22	49	4	PF00324
Domain	-	ERN1 EIF2AK3	1.00e-04	6	49	2	2.140.10.10
Domain	Quinoprotein_ADH-like_fam	ERN1 EIF2AK3	1.00e-04	6	49	2	IPR027295
Domain	FN3	FLNC NEO1 IGDCC3 ROS1 SDK1	1.21e-04	185	49	5	SM00060
Domain	FN3_dom	FLNC NEO1 IGDCC3 ROS1 SDK1	2.14e-04	209	49	5	IPR003961
Domain	IG_FLMN	FLNB FLNC	2.99e-04	10	49	2	SM00557
Domain	Quinoprotein_ADH-like_supfam	ERN1 WDR1 EIF2AK3	3.62e-04	53	49	3	IPR011047
Domain	Filamin	FLNB FLNC	3.65e-04	11	49	2	PF00630
Domain	FILAMIN_REPEAT	FLNB FLNC	3.65e-04	11	49	2	PS50194
Domain	Filamin/ABP280_rpt	FLNB FLNC	3.65e-04	11	49	2	IPR001298
Domain	Filamin/ABP280_repeat-like	FLNB FLNC	3.65e-04	11	49	2	IPR017868
Domain	Kinase-like_dom	MOK ERN1 PIK3C2A HIPK2 ROCK1 ROS1 EIF2AK3	4.98e-04	542	49	7	IPR011009
Domain	CH	CFAP47 FLNB FLNC	8.21e-04	70	49	3	PF00307
Domain	fn3	NEO1 IGDCC3 ROS1 SDK1	8.53e-04	162	49	4	PF00041
Domain	-	CFAP47 FLNB FLNC	8.56e-04	71	49	3	1.10.418.10
Domain	CH	CFAP47 FLNB FLNC	9.28e-04	73	49	3	PS50021
Domain	CH-domain	CFAP47 FLNB FLNC	1.00e-03	75	49	3	IPR001715
Domain	PROTEIN_KINASE_ATP	MOK ERN1 HIPK2 ROCK1 ROS1 EIF2AK3	1.22e-03	459	49	6	PS00107
Domain	Actinin_actin-bd_CS	FLNB FLNC	1.65e-03	23	49	2	IPR001589
Domain	ACTININ_2	FLNB FLNC	1.65e-03	23	49	2	PS00020
Domain	ACTININ_1	FLNB FLNC	1.65e-03	23	49	2	PS00019
Domain	Prot_kinase_dom	MOK ERN1 HIPK2 ROCK1 ROS1 EIF2AK3	1.68e-03	489	49	6	IPR000719
Domain	PROTEIN_KINASE_DOM	MOK ERN1 HIPK2 ROCK1 ROS1 EIF2AK3	1.75e-03	493	49	6	PS50011
Domain	FN3	NEO1 IGDCC3 ROS1 SDK1	1.82e-03	199	49	4	PS50853
Domain	Ser/Thr_kinase_AS	MOK ERN1 HIPK2 ROCK1 EIF2AK3	2.37e-03	357	49	5	IPR008271
Domain	S_TKc	MOK ERN1 HIPK2 ROCK1 EIF2AK3	2.43e-03	359	49	5	SM00220
Domain	PROTEIN_KINASE_ST	MOK ERN1 HIPK2 ROCK1 EIF2AK3	2.52e-03	362	49	5	PS00108
Domain	Protein_kinase_ATP_BS	MOK HIPK2 ROCK1 ROS1 EIF2AK3	3.07e-03	379	49	5	IPR017441
Domain	Pkinase	MOK ERN1 HIPK2 ROCK1 EIF2AK3	3.14e-03	381	49	5	PF00069
Domain	PX	PIK3C2A SNX19	5.95e-03	44	49	2	SM00312
Domain	PX	PIK3C2A SNX19	7.33e-03	49	49	2	PF00787
Domain	-	FLNB FLNC NEO1 IGDCC3 ROS1 SDK1	7.47e-03	663	49	6	2.60.40.10
Domain	PX	PIK3C2A SNX19	7.62e-03	50	49	2	PS50195
Domain	-	PIK3C2A SNX19	7.92e-03	51	49	2	3.30.1520.10
Domain	Phox	PIK3C2A SNX19	8.22e-03	52	49	2	IPR001683
Domain	Sushi	CR2 CFB	8.22e-03	52	49	2	PF00084
Domain	CCP	CR2 CFB	8.85e-03	54	49	2	SM00032
Domain	WD40_repeat_CS	WDR1 LYST BRWD1	9.11e-03	164	49	3	IPR019775
Domain	SUSHI	CR2 CFB	9.49e-03	56	49	2	PS50923
Domain	Sushi_SCR_CCP_dom	CR2 CFB	9.82e-03	57	49	2	IPR000436
Domain	Ig-like_fold	FLNB FLNC NEO1 IGDCC3 ROS1 SDK1	1.00e-02	706	49	6	IPR013783
Pathway	REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE	SLC7A1 SLC7A2 SLC7A3	6.08e-05	33	33	3	M188
Pathway	REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES	SLC7A1 SLC7A2 SLC7A3 SLC26A4	1.12e-04	108	33	4	M823
Pathway	WP_ACQUIRED_PARTIAL_LIPODYSTROPHY_BARRAQUERSIMONS_SYNDROME	LMNB1 CFB	2.36e-04	10	33	2	M42576
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	SLC6A1 SLC7A1 SLC7A2 SLC7A3 SLC26A4	2.62e-04	249	33	5	M5988
Pathway	WP_NPHP1_DELETION_SYNDROME	FLNB FLNC	2.88e-04	11	33	2	M48099
Pathway	WP_VEGFAVEGFR2_SIGNALING	FLNB SLC7A1 ACACB ERN1 ROCK1 EIF2AK3	4.33e-04	431	33	6	M39729
Pubmed	Differential topochemistry of three cationic amino acid transporter proteins, hCAT1, hCAT2 and hCAT3, in the adult human brain.	SLC7A1 SLC7A2 SLC7A3	2.97e-09	3	51	3	22870827
Pubmed	A new member of the cationic amino acid transporter family is preferentially expressed in adult mouse brain.	SLC7A1 SLC7A2 SLC7A3	2.97e-09	3	51	3	9334265
Pubmed	HIV Tat-Mediated Induction of Human Brain Microvascular Endothelial Cell Apoptosis Involves Endoplasmic Reticulum Stress and Mitochondrial Dysfunction.	ERN1 ROS1 EIF2AK3	2.48e-07	9	51	3	25409632
Pubmed	Improved IRE1 and PERK Pathway Sensors for Multiplex Endoplasmic Reticulum Stress Assay Reveal Stress Response to Nuclear Dyes Used for Image Segmentation.	ERN1 EIF2AK3	2.11e-06	2	51	2	30088945
Pubmed	Hypoxia in 3T3-L1 adipocytes suppresses adiponectin expression via the PERK and IRE1 unfolded protein response.	ERN1 EIF2AK3	2.11e-06	2	51	2	28888981
Pubmed	A molecular chaperone inducer protects neurons from ER stress.	ERN1 EIF2AK3	2.11e-06	2	51	2	18049481
Pubmed	Increased Cat3-mediated cationic amino acid transport functionally compensates in Cat1 knockout cell lines.	SLC7A1 SLC7A3	2.11e-06	2	51	2	9614060
Pubmed	Activation of endoplasmic reticulum stress mediates oxidative stress-induced apoptosis of granulosa cells in ovaries affected by endometrioma.	ERN1 EIF2AK3	2.11e-06	2	51	2	31869409
Pubmed	Endoplasmic reticulum stress-independent activation of unfolded protein response kinases by a small molecule ATP-mimic.	ERN1 EIF2AK3	2.11e-06	2	51	2	25986605
Pubmed	Regulation of the unfolded protein response via S-nitrosylation of sensors of endoplasmic reticulum stress.	ERN1 EIF2AK3	2.11e-06	2	51	2	26446798
Pubmed	Human cationic amino acid transporters are not affected by direct nitros(yl)ation.	SLC7A1 SLC7A2	2.11e-06	2	51	2	32008093
Pubmed	Multivesicular body formation enhancement and exosome release during endoplasmic reticulum stress.	ERN1 EIF2AK3	2.11e-06	2	51	2	27725157
Pubmed	A chimera carrying the functional domain of the orphan protein SLC7A14 in the backbone of SLC7A2 mediates trans-stimulated arginine transport.	SLC7A2 SLC7A14	2.11e-06	2	51	2	22787143
Pubmed	The limits of promiscuity: isoform-specific dimerization of filamins.	FLNB FLNC	2.11e-06	2	51	2	12525170
Pubmed	Identification of a low affinity, high capacity transporter of cationic amino acids in mouse liver.	SLC7A1 SLC7A2	2.11e-06	2	51	2	8385111
Pubmed	The prognostic biomarker L-homoarginine is a substrate of the cationic amino acid transporters CAT1, CAT2A and CAT2B.	SLC7A1 SLC7A2	2.11e-06	2	51	2	28684763
Pubmed	A novel human actin-binding protein homologue that binds to platelet glycoprotein Ibalpha.	FLNB FLNC	2.11e-06	2	51	2	9694715
Pubmed	The importance of cationic amino acid transporter expression in human skin.	SLC7A1 SLC7A2	2.11e-06	2	51	2	12787129
Pubmed	Novel prosurvival function of Yip1A in human cervical cancer cells: constitutive activation of the IRE1 and PERK pathways of the unfolded protein response.	ERN1 EIF2AK3	2.11e-06	2	51	2	28358375
Pubmed	The Role of Unfolded Protein Response in Human Intervertebral Disc Degeneration: Perk and IRE1-α as Two Potential Therapeutic Targets.	ERN1 EIF2AK3	2.11e-06	2	51	2	33833850
Pubmed	Regulation of cationic amino acid transporter (CAT) gene expression.	SLC7A1 SLC7A2	2.11e-06	2	51	2	8878860
Pubmed	Cell signalling-mediating insulin increase of mRNA expression for cationic amino acid transporters-1 and -2 and membrane hyperpolarization in human umbilical vein endothelial cells.	SLC7A1 SLC7A2	2.11e-06	2	51	2	15064952
Pubmed	New small molecule inhibitors of UPR activation demonstrate that PERK, but not IRE1α signaling is essential for promoting adaptation and survival to hypoxia.	ERN1 EIF2AK3	2.11e-06	2	51	2	23830192
Pubmed	Human cationic amino acid transporters hCAT-1, hCAT-2A, and hCAT-2B: three related carriers with distinct transport properties.	SLC7A1 SLC7A2	2.11e-06	2	51	2	9174363
Pubmed	Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival.	ERN1 EIF2AK3	2.11e-06	2	51	2	11430819
Pubmed	A Phos-tag-based approach reveals the extent of physiological endoplasmic reticulum stress.	ERN1 EIF2AK3	2.11e-06	2	51	2	20661282
Pubmed	A close connection between the PERK and IRE arms of the UPR and the transcriptional regulation of autophagy.	ERN1 EIF2AK3	2.11e-06	2	51	2	25475719
Pubmed	Human cationic amino acid transporter hCAT-3 is preferentially expressed in peripheral tissues.	SLC7A1 SLC7A3	2.11e-06	2	51	2	11591158
Pubmed	Control of cationic amino acid transport and retroviral receptor functions in a membrane protein family.	SLC7A1 SLC7A2	2.11e-06	2	51	2	8195186
Pubmed	Characterization of cationic amino acid transporters (hCATs) 1 and 2 in human skin.	SLC7A1 SLC7A2	2.11e-06	2	51	2	18172665
Pubmed	Deficiency of IRE1 and PERK signal pathways in systemic lupus erythematosus.	ERN1 EIF2AK3	2.11e-06	2	51	2	25226532
Pubmed	Endoplasmic Reticulum Stress in Colonic Mucosa of Ulcerative Colitis Patients Is Mediated by PERK and IRE1 Pathway Activation.	ERN1 EIF2AK3	2.11e-06	2	51	2	35185383
Pubmed	Radiation induces EIF2AK3/PERK and ERN1/IRE1 mediated pro-survival autophagy.	ERN1 EIF2AK3	2.11e-06	2	51	2	30773986
Pubmed	Noncanonical binding of BiP ATPase domain to Ire1 and Perk is dissociated by unfolded protein CH1 to initiate ER stress signaling.	ERN1 EIF2AK3	6.32e-06	3	51	2	25692299
Pubmed	Rate of transport of l-arginine is independent of the expression of inducible nitric oxide synthase in HEK 293 cells.	SLC7A1 SLC7A2	6.32e-06	3	51	2	15631944
Pubmed	Filamins as integrators of cell mechanics and signalling.	FLNB FLNC	6.32e-06	3	51	2	11252955
Pubmed	Expression of markers of endoplasmic reticulum stress-induced apoptosis in the placenta of women with early and late onset severe pre-eclampsia.	ERN1 EIF2AK3	6.32e-06	3	51	2	25675914
Pubmed	Fatty acid palmitate suppresses FoxO1 expression via PERK and IRE1 unfolded protein response in C2C12 myotubes.	ERN1 EIF2AK3	6.32e-06	3	51	2	36030031
Pubmed	Analysis of the genomic organization of the human cationic amino acid transporters CAT-1, CAT-2 and CAT-4.	SLC7A1 SLC7A2	6.32e-06	3	51	2	11665818
Pubmed	ER stress activates NF-κB by integrating functions of basal IKK activity, IRE1 and PERK.	ERN1 EIF2AK3	6.32e-06	3	51	2	23110043
Pubmed	UPR proteins IRE1 and PERK switch BiP from chaperone to ER stress sensor.	ERN1 EIF2AK3	6.32e-06	3	51	2	31695187
Pubmed	Dynamic changes in complexes of IRE1α, PERK, and ATF6α during endoplasmic reticulum stress.	ERN1 EIF2AK3	6.32e-06	3	51	2	29851562
Pubmed	Human GRP78 affinity towards its signaling partners Ire1α and PERK is differently modulated by an unfolded protein client.	ERN1 EIF2AK3	6.32e-06	3	51	2	28416388
Pubmed	Targeting UPR branches, a potential strategy for enhancing efficacy of cancer chemotherapy.	ERN1 EIF2AK3	6.32e-06	3	51	2	34664059
Pubmed	Growth differentiation factor 15 ameliorates nonalcoholic steatohepatitis and related metabolic disorders in mice.	ERN1 EIF2AK3	6.32e-06	3	51	2	29717162
Pubmed	The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response.	ERN1 EIF2AK3	6.32e-06	3	51	2	16973740
Pubmed	Multiple Mechanisms of Unfolded Protein Response-Induced Cell Death.	ERN1 EIF2AK3	6.32e-06	3	51	2	25956028
Pubmed	Unfolding anti-tumor immunity: ER stress responses sculpt tolerogenic myeloid cells in cancer.	ERN1 EIF2AK3	6.32e-06	3	51	2	28105371
Pubmed	Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha.	ERN1 EIF2AK3	6.32e-06	3	51	2	12446770
Pubmed	Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact.	FLNB FLNC	6.32e-06	3	51	2	12393796
Pubmed	Transcriptional regulation of VEGF-A by the unfolded protein response pathway.	ERN1 EIF2AK3	6.32e-06	3	51	2	20221394
Pubmed	The role of unfolded protein response in the pathogenesis of endometriosis: contribution of peritoneal fluid.	ERN1 EIF2AK3	6.32e-06	3	51	2	33109440
Pubmed	The Malat1 long non-coding RNA is upregulated by signalling through the PERK axis of unfolded protein response during flavivirus infection.	ERN1 EIF2AK3	6.32e-06	3	51	2	26634309
Pubmed	Unfolded protein response.	ERN1 EIF2AK3	6.32e-06	3	51	2	22917505
Pubmed	HIV infection and antiretroviral therapy lead to unfolded protein response activation.	ERN1 EIF2AK3	6.32e-06	3	51	2	25976933
Pubmed	ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress.	ERN1 EIF2AK3	6.32e-06	3	51	2	17765679
Pubmed	JAB1 participates in unfolded protein responses by association and dissociation with IRE1.	ERN1 EIF2AK3	6.32e-06	3	51	2	15234121
Pubmed	Binding of human BiP to the ER stress transducers IRE1 and PERK requires ATP.	ERN1 EIF2AK3	6.32e-06	3	51	2	22446326
Pubmed	Genomic structure and fine mapping of the two human filamin gene paralogues FLNB and FLNC and comparative analysis of the filamin gene family.	FLNB FLNC	6.32e-06	3	51	2	11153914
Pubmed	ROCK-mediated selective activation of PERK signalling causes fibroblast reprogramming and tumour progression through a CRELD2-dependent mechanism.	ROCK1 EIF2AK3	6.32e-06	3	51	2	32451439
Pubmed	Function and mutual interaction of BiP-, PERK-, and IRE1α-dependent signalling pathways in vascular tumours.	ERN1 EIF2AK3	6.32e-06	3	51	2	32166747
Pubmed	PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK- and IRE1α-mediated unfolded protein response.	ERN1 EIF2AK3	6.32e-06	3	51	2	23103912
Pubmed	GRASP55 and UPR Control Interleukin-1β Aggregation and Secretion.	ERN1 EIF2AK3	1.26e-05	4	51	2	30880003
Pubmed	Novel mechanism of enhancing IRE1α-XBP1 signalling via the PERK-ATF4 pathway.	ERN1 EIF2AK3	1.26e-05	4	51	2	27052593
Pubmed	Coordination between Two Branches of the Unfolded Protein Response Determines Apoptotic Cell Fate.	ERN1 EIF2AK3	1.26e-05	4	51	2	30118681
Pubmed	The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin.	FLNB FLNC	1.26e-05	4	51	2	11739414
Pubmed	Structural interaction and functional regulation of polycystin-2 by filamin.	FLNB FLNC	1.26e-05	4	51	2	22802962
Pubmed	Induction of Endoplasmic Reticulum Stress Pathway by Green Tea Epigallocatechin-3-Gallate (EGCG) in Colorectal Cancer Cells: Activation of PERK/p-eIF2α/ATF4 and IRE1α.	ERN1 EIF2AK3	1.26e-05	4	51	2	31930117
Pubmed	The effects of IRE1, ATF6, and PERK signaling on adRP-linked rhodopsins.	ERN1 EIF2AK3	1.26e-05	4	51	2	24664756
Pubmed	Cloning and expression of nope, a new mouse gene of the immunoglobulin superfamily related to guidance receptors.	NEO1 IGDCC3	1.26e-05	4	51	2	10708514
Pubmed	Imaging of single cell responses to ER stress indicates that the relative dynamics of IRE1/XBP1 and PERK/ATF4 signalling rather than a switch between signalling branches determine cell survival.	ERN1 EIF2AK3	1.26e-05	4	51	2	25633195
Pubmed	Ufbp1 promotes plasma cell development and ER expansion by modulating distinct branches of UPR.	ERN1 EIF2AK3	1.26e-05	4	51	2	30842412
Pubmed	Ursolic acid induces ER stress response to activate ASK1-JNK signaling and induce apoptosis in human bladder cancer T24 cells.	ERN1 EIF2AK3	1.26e-05	4	51	2	23000344
Pubmed	Perk is essential for translational regulation and cell survival during the unfolded protein response.	ERN1 EIF2AK3	1.26e-05	4	51	2	10882126
Pubmed	MCD diet-induced steatohepatitis is associated with alterations in asymmetric dimethylarginine (ADMA) and its transporters.	SLC7A1 SLC7A2	1.26e-05	4	51	2	27357826
Pubmed	Compounds Triggering ER Stress Exert Anti-Melanoma Effects and Overcome BRAF Inhibitor Resistance.	ERN1 EIF2AK3	1.26e-05	4	51	2	27238082
Pubmed	Loss of ATF6α in a human carcinoma cell line is compensated not by its paralogue ATF6β but by sustained activation of the IRE1 and PERK arms for tumor growth in nude mice.	ERN1 EIF2AK3	1.26e-05	4	51	2	36696173
Pubmed	Amino acid transport across mammalian intestinal and renal epithelia.	SLC7A1 SLC7A2 SLC7A3	1.30e-05	31	51	3	18195088
Pubmed	Blood-Brain Barrier: From Physiology to Disease and Back.	SLC6A1 SLC7A1 SLC7A2 SLC7A3	1.76e-05	105	51	4	30280653
Pubmed	UPR-induced resistance to etoposide is downstream of PERK and independent of changes in topoisomerase IIα levels.	ERN1 EIF2AK3	2.10e-05	5	51	2	23144714
Pubmed	Nitric oxide signalling pathway in Duchenne muscular dystrophy mice: up-regulation of L-arginine transporters.	SLC7A1 SLC7A2	2.10e-05	5	51	2	23009292
Pubmed	Y+ and y+ L arginine transporters in neuronal cells expressing tyrosine hydroxylase.	SLC7A1 SLC7A3	2.10e-05	5	51	2	16085056
Pubmed	IRE1α-XBP1 signaling in leukocytes controls prostaglandin biosynthesis and pain.	ERN1 EIF2AK3	2.10e-05	5	51	2	31320508
Pubmed	HIV infection of T cells: actin-in and actin-out.	FLNB FLNC	2.10e-05	5	51	2	19366992
Pubmed	Nephrocystin-conserved domains involved in targeting to epithelial cell-cell junctions, interaction with filamins, and establishing cell polarity.	FLNB FLNC	2.10e-05	5	51	2	12006559
Pubmed	Complement-dependent injury and protection in a murine model of acute dextran sulfate sodium-induced colitis.	CR2 CFB	2.10e-05	5	51	2	22566568
Pubmed	MicroRNA-30c-2* limits expression of proadaptive factor XBP1 in the unfolded protein response.	ERN1 EIF2AK3	2.10e-05	5	51	2	22431749
Pubmed	Filamin B deficiency in mice results in skeletal malformations and impaired microvascular development.	FLNB FLNC	2.10e-05	5	51	2	17360453
Pubmed	IRE1 prevents endoplasmic reticulum membrane permeabilization and cell death under pathological conditions.	ERN1 EIF2AK3	3.15e-05	6	51	2	26106220
Pubmed	Stage-specific expression patterns of ER stress-related molecules in mice molars: Implications for tooth development.	ERN1 EIF2AK3	3.15e-05	6	51	2	32758541
Pubmed	IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2.	ERN1 EIF2AK3	3.15e-05	6	51	2	23042294
Pubmed	Deltex3 inhibits Epithelial Mesenchymal Transition in Papillary Thyroid Carcinoma via promoting ubiquitination of XRCC5 to regulate the AKT signal pathway.	FLNB FLNC DTX3	4.31e-05	46	51	3	33403043
Pubmed	Arthritis critically dependent on innate immune system players.	CR2 CFB	4.41e-05	7	51	2	11869678
Pubmed	Complement facilitates early prion pathogenesis.	CR2 CFB	4.41e-05	7	51	2	11283678
Pubmed	Ubiquitination of ATF6 by disease-associated RNF186 promotes the innate receptor-induced unfolded protein response.	ERN1 EIF2AK3	4.41e-05	7	51	2	34623328
Pubmed	The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins.	FLNB FLNC	4.41e-05	7	51	2	16076904
Pubmed	AATF mediates an antiapoptotic effect of the unfolded protein response through transcriptional regulation of AKT1.	ERN1 EIF2AK3	4.41e-05	7	51	2	19911006
Pubmed	Cutting Edge: Neutrophil Complement Receptor Signaling Is Required for BAFF-Dependent Humoral Responses in Mice.	CR2 CFB	4.41e-05	7	51	2	36454023
Pubmed	Death protein 5 and p53-upregulated modulator of apoptosis mediate the endoplasmic reticulum stress-mitochondrial dialog triggering lipotoxic rodent and human β-cell apoptosis.	ERN1 EIF2AK3	4.41e-05	7	51	2	22773666
Pubmed	MEKK4 signaling regulates filamin expression and neuronal migration.	FLNB FLNC	5.87e-05	8	51	2	17145501
Cytoband	15q22.3-q23	NEO1 IGDCC3	7.25e-06	4	51	2	15q22.3-q23
Cytoband	3p25.3	SLC6A1 SETD5	1.16e-03	45	51	2	3p25.3
GeneFamily	Solute carriers	SLC6A1 SLC7A1 SLC7A2 SLC7A3 SLC26A4 SLC7A14	9.94e-05	395	35	6	752
GeneFamily	Fibronectin type III domain containing	NEO1 IGDCC3 ROS1 SDK1	2.50e-04	160	35	4	555
GeneFamily	Complement system\|Sushi domain containing	CR2 CFB	2.20e-03	36	35	2	492
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	NEO1 IGDCC3 SDK1	3.68e-03	161	35	3	593
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	CR2 CFB	5.44e-03	57	35	2	1179
GeneFamily	WD repeat domain containing	WDR1 LYST BRWD1	1.40e-02	262	35	3	362
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC7A1 SLC7A2 ACACB ROS1 SDK1	8.26e-07	151	51	5	f4f7156b2c0cfc78fd1841e07c9915d97ced561f
ToppCell	Club_cells-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	SLC6A1 SOHLH2 SLC26A4 IGDCC3 CFB	1.36e-06	167	51	5	dbdaaeb3bd9139cb008d9fe24ec031fc5628f136
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC7A2 FBLN5 PLEKHH2 LDLRAD3 SDK1	1.96e-06	180	51	5	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC7A2 FBLN5 PLEKHH2 LDLRAD3 SDK1	1.96e-06	180	51	5	9b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC7A2 FBLN5 TMEM165 SGPP2 ROS1	2.49e-06	189	51	5	e90ba6f6d7ba0698d04d84278aa035c28803733e
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SLC7A2 TMEM165 PLEKHH2 LDLRAD3 SDK1	2.62e-06	191	51	5	08720998aa55131d7377c4c67c4c935865bd7d79
ToppCell	COVID-19-kidney-Plasma\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ERN1 MEI1 IGHV4-39 EIF2AK3	3.38e-05	160	51	4	f8d9e459976e711e9ad39ea2b6173140c0589d6e
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs\|Fibroblasts / Location, Cell class and cell subclass	MOK FBLN5 PLEKHH2 CFB	4.18e-05	169	51	4	84b898a9fd8ced67c6a501d5cef6416f519902c4
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-BM_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGFAC NEO1 ACACB C1QL3	4.38e-05	171	51	4	6f49537f8d3cf18e65aa999fec32ed347ce2da3e
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGFAC NEO1 ACACB C1QL3	4.38e-05	171	51	4	ab97ae2b127a585f170f028f1c475cdd1b0cdea5
ToppCell	Control-B_cells-Plasma_cells\|Control / group, cell type (main and fine annotations)	ERN1 HIPK2 MEI1 EIF2AK3	4.79e-05	175	51	4	fb23858cfce71509cafbe0d9728e678012ff2962
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC6A1 SLC7A2 PLEKHH2 SDK1	4.79e-05	175	51	4	11f49f00e000cbc137e3540a6d6805cde21d96e6
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC6A1 SLC7A2 PLEKHH2 SDK1	4.90e-05	176	51	4	4843af68f013732c28a8b8edad30d5fa0f2b084b
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L1-6_PVALB_SCUBE3_(Chandelier_1)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC6A1 SLC7A2 PLEKHH2 SDK1	4.90e-05	176	51	4	95d5a4fdff1b9c715636684d22e06f8727ac0e7a
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC6A1 FLNC SLC7A2 SDK1	5.01e-05	177	51	4	1cb78133ac09ea3a3f5b5de07151033998406512
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L3-6_PVALB_MFI2_(Chandelier_2)\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC6A1 SLC7A2 PLEKHH2 SDK1	5.01e-05	177	51	4	4f88ea4cfcfa8a9af5a14ab6f6be3b2aa015852e
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FBLN5 OLFM3 SGPP2 SDK1	5.01e-05	177	51	4	bde307e67ad8e48a5ff4c0827015f4688f6b3e46
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ERN1 MEI1 IGHV4-39 EIF2AK3	5.12e-05	178	51	4	f815bc76f98aaea2d9058173b02b6f36e45283ce
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ERN1 MEI1 IGHV4-39 EIF2AK3	5.12e-05	178	51	4	a0334764e865fea652c54b94bbc3b173f7cbc9fc
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L3-6_PVALB_MFI2_(Chandelier_2)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC6A1 SLC7A2 PLEKHH2 SDK1	5.12e-05	178	51	4	c982a73955c9c193bcab21d60d453afcc09cd586
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FBLN5 OLFM3 SGPP2 SDK1	5.23e-05	179	51	4	7954c0026754ab869b88ab7feb13c2f27d6e272d
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC6A1 SLC7A2 PLEKHH2 SDK1	5.23e-05	179	51	4	3b0f8781232e1d42b6f8913bc989a14b3f978e79
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC6A1 HGFAC SLC7A2 SDK1	5.23e-05	179	51	4	97ba67a856680f24846244c0b92c886cc0e79537
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MOK CFAP47 SPAG1 REEP2	5.35e-05	180	51	4	0c146e80d55d18b6988dd21b1da635801bd3140c
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MOK CFAP47 SPAG1 REEP2	5.35e-05	180	51	4	e9af22beae2f3c7fe213b4e19df84abfd2453433
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MOK CFAP47 SPAG1 REEP2	5.35e-05	180	51	4	11455ba704ac73f69b474845136cfecec6a88349
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC7A2 FBLN5 PLEKHH2 SDK1	5.46e-05	181	51	4	9e7d0f1afb8d9bc5a209ddb5314df3a25a0274d9
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ERN1 MEI1 IGHV4-39 EIF2AK3	5.46e-05	181	51	4	6cdee2f56bc633b387b4dbbd78c624edbd712c24
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ERN1 MEI1 IGHV4-39 EIF2AK3	5.46e-05	181	51	4	b75b8b025257bccfe661fd0f92ab284b2a9c12ee
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC6A1 SLC7A2 PLEKHH2 SDK1	5.46e-05	181	51	4	153709b4dd3d81e09f251fa8765b58bed1932fda
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ERN1 MEI1 IGHV4-39 EIF2AK3	5.46e-05	181	51	4	5a4fe0eca7cbc9cbc8a2fdbe795a7c5f4052a659
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC6A1 HGFAC SLC7A2 SDK1	5.58e-05	182	51	4	7dc61e901428cea04f00ebb0939a44d21a6145c6
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC6A1 HGFAC IGDCC3 SDK1	5.58e-05	182	51	4	3d7a8d2ee2137b098248597058974ef5ae09c19e
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ERN1 HIPK2 MEI1 EIF2AK3	5.58e-05	182	51	4	626aabfd9ac662c1d189f7c4b660482914d9e669
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-Plasma_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ERN1 HIPK2 MEI1 EIF2AK3	5.58e-05	182	51	4	a00abff41c12b71d5860c494b8c722d649fd5f36
ToppCell	RA-13._Vascular_Smooth_Muscle\|RA / Chamber and Cluster_Paper	FLNB SLC7A2 ROCK1 SDK1	5.70e-05	183	51	4	818fd886e0188091310825f9145fa53328f2c979
ToppCell	COVID-19-B_cells-Plasma_cells\|COVID-19 / group, cell type (main and fine annotations)	ERN1 HIPK2 MEI1 EIF2AK3	5.70e-05	183	51	4	130c109f63a5e3c8f83cb96e32f4addf513b6415
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC6A1 HGFAC SLC7A2 SDK1	5.70e-05	183	51	4	e3ffef2b57dc5b96466dccc9cd54ba326ccf378a
ToppCell	COVID-19-B_cells\|COVID-19 / group, cell type (main and fine annotations)	ERN1 HIPK2 MEI1 EIF2AK3	5.70e-05	183	51	4	2c016bb59f131a0e821853b085289a3583f0a729
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC6A1 HGFAC SLC7A2 SDK1	5.95e-05	185	51	4	16e9ccea0e3b95d90dc48ef74206c805681dac0b
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC6A1 HGFAC SLC7A2 SDK1	5.95e-05	185	51	4	487fa382232564f075960899d50afa0edae5d258
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC6A1 HGFAC SLC7A2 SLC7A14	5.95e-05	185	51	4	79cff4f3c6ae8e5ea60e8eae082b9275f2679ee9
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	SLC26A4 SGPP2 ROS1 SDK1	5.95e-05	185	51	4	cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC6A1 HGFAC SLC7A2 SDK1	5.95e-05	185	51	4	08fad1e3c3cc5f1c3eb6629a49c094b628e75a92
ToppCell	COVID-19-kidney-Fibroblast-1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLC7A2 FBLN5 LDLRAD3 SDK1	6.20e-05	187	51	4	76bfe8c42430a230a8bdf299575c444fb7780f24
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-Undetermined\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	FBLN5 PLEKHH2 LDLRAD3 REEP2	6.33e-05	188	51	4	8231e635706a296db6b6da1029a33bbc1b52478e
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D175\|Adult / Lineage, Cell type, age group and donor	SLC7A1 SLC7A2 SGPP2 ROS1	6.33e-05	188	51	4	ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCell	COPD-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	SPAG1 LMNB1 SGPP2 RFX3	6.33e-05	188	51	4	186fe1ea328c942910190a4240262c0d8642ea3b
ToppCell	droplet-Kidney-nan-18m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNB ACACB SLC26A4 SGPP2	6.59e-05	190	51	4	c408d4033a130c0168159a5b6f286fd2b2a9a39d
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam____kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNB ACACB SLC26A4 SGPP2	6.59e-05	190	51	4	d4910c37045a8b8bb53b37625263bc0a47b6e3f8
ToppCell	COPD-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	SLC7A2 FBLN5 ACACB LYST	6.73e-05	191	51	4	ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCell	10x5'v1-week_14-16-Mesenchymal_fibro-stroma-endosteal_fibroblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	SLC6A1 FLNC SLC26A4 IGDCC3	6.73e-05	191	51	4	44b1f62fdee03b157fe545f2ae6ff84f8929a8ac
ToppCell	Control-Plasmablast\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	ERN1 HIPK2 MEI1 IGHV4-39	6.73e-05	191	51	4	3df5bbdb29bbcbcb8476fdf126b6d4c1ac67d64b
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3\|lymph-node_spleen / Manually curated celltypes from each tissue	SPAG1 NEO1 HIPK2 LDLRAD3	6.87e-05	192	51	4	e16035b3328f9b1b2e28d234c62ba88387540550
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC7A2 FBLN5 PLEKHH2 SDK1	6.87e-05	192	51	4	3d0cb19f037f604253d7d728689aeaa94251e92b
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC7A2 FBLN5 PLEKHH2 SDK1	6.87e-05	192	51	4	deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC7A2 FBLN5 PLEKHH2 SDK1	7.01e-05	193	51	4	fb28717fadd06c3840636d25409ce80c9254bd34
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM165 SLC26A4 SGPP2 CFB	7.15e-05	194	51	4	855d6acfcf323868ba98b213f06186ad4793d4ed
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM165 SLC26A4 SGPP2 CFB	7.15e-05	194	51	4	dc531cf9089f2c956621d70d49a2b8219b4b45c1
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM165 SLC26A4 SGPP2 CFB	7.15e-05	194	51	4	29a7770bdbea6081a9ed64a997cd92a1cbf4af58
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC7A2 FBLN5 PLEKHH2 SDK1	7.15e-05	194	51	4	60622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM165 SLC26A4 SGPP2 CFB	7.15e-05	194	51	4	ca051088f880154ae2fd3f0ab3cef5a8dba8c371
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells-IgG_plasma_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ERN1 HIPK2 MEI1 IGHV4-39	7.15e-05	194	51	4	f083777353e76a2d9c39f8b6cb1a689b68b81c56
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC7A2 PLEKHH2 LDLRAD3 SDK1	7.15e-05	194	51	4	89b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MOK CFAP47 SPAG1 RFX3	7.15e-05	194	51	4	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MOK SPAG1 SLC26A4 RFX3	7.29e-05	195	51	4	d211a836cf711fdb91b10d512f09d462be937cc5
ToppCell	COVID-19-kidney-Fibroblast-2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLC7A2 FBLN5 LDLRAD3 SDK1	7.29e-05	195	51	4	3d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCell	5'-Adult-SmallIntestine-Hematopoietic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MS4A4A ERN1 HIPK2 MEI1	7.44e-05	196	51	4	008e7593ab26988b957673f863bdd017516281ae
ToppCell	NS-moderate-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MOK CFAP47 SPAG1 RFX3	7.58e-05	197	51	4	71fea4aa6ce96c7693fa94792d08770622873850
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B-B_plasma\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ERN1 HIPK2 MEI1 EIF2AK3	7.73e-05	198	51	4	567fcf882c8612356946240843525b786f3c8dbe
ToppCell	(10)_Ciliated-(2)_GFP_FOXI1\|(10)_Ciliated / shred by cell type by condition	SPAG1 DTX3 ROCK1 RFX3	7.89e-05	199	51	4	61b1ed2db71b96157b92b7535d1955a4033098da
ToppCell	Sigmoid-T_cell-Th17\|T_cell / Region, Cell class and subclass	FLNB NEO1 ERN1 HIPK2	7.89e-05	199	51	4	622f2ae4b1850b25f723a0385da49147dfec8285
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-SCUBE3\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SLC6A1 SLC7A2 PLEKHH2 SDK1	8.04e-05	200	51	4	2441a36d363b799a4692aa697f969cda056c2d60
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SLC6A1 CFAP47 PIK3C2A GABRA2	8.04e-05	200	51	4	07d942803360e1a1e8e131d6e31c726dd0db1a0b
ToppCell	Neuronal-Inhibitory-iA\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SLC6A1 HGFAC SLC7A2 SDK1	8.04e-05	200	51	4	5ef4a3dc18a44292184a59ced916183c0699b01e
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-SCUBE3-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SLC6A1 SLC7A2 PLEKHH2 SDK1	8.04e-05	200	51	4	c7bca638229bd4fd2414171e73fa949e36a10a92
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-SCUBE3--L2-5\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SLC6A1 SLC7A2 PLEKHH2 SDK1	8.04e-05	200	51	4	d841dbe2297c3bf62f49bae5921662cd6a47e5c2
ToppCell	LPS-IL1RA-Epithelial_alveolar-Mes-Like-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLNC KLHL31 GABRA2	2.24e-04	103	51	3	eb9f008b5fb8a01df8ea4faf6e6aebc1a9db9bd3
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nptxr-Excitatory_Neuron.Slc17a7.Nptxr-Deptor_(Deep_layer_pyramidal_cells--Layer_5a)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	C1QL3 SLC26A4 MEI1	2.58e-04	108	51	3	514dfc3f7ac303311ae599f981f3f3c7eb6801b8
ToppCell	Striatum-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Excitatory_Neuron.Slc17a7.Dkk3_(Deep_layer_cortex)-\|Striatum / BrainAtlas - Mouse McCarroll V32	C1QL3 SLC26A4 SDK1	3.02e-04	114	51	3	3352ce794a646e3e7f15a991dd8a847a3c705394
ToppCell	Striatum-Neuronal-Excitatory-eN1(Slc17a7)\|Striatum / BrainAtlas - Mouse McCarroll V32	C1QL3 SLC26A4 SDK1	3.02e-04	114	51	3	158dc333b337d5e83183b2f010a8e030c7a57bc7
ToppCell	Striatum-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Excitatory_Neuron.Slc17a7.Dkk3_(Deep_layer_cortex)\|Striatum / BrainAtlas - Mouse McCarroll V32	C1QL3 SLC26A4 SDK1	3.02e-04	114	51	3	238f2541e0514df8d24d767f833980d770b920a4
ToppCell	Striatum-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1\|Striatum / BrainAtlas - Mouse McCarroll V32	C1QL3 SLC26A4 SDK1	3.02e-04	114	51	3	e63c0ebf843392c2926732bb8792eb6ee69bec15
ToppCell	Control-Developping_Plasmablast\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	SLC7A1 LMNB1 REEP2	3.51e-04	120	51	3	695dab6b01ad2c33cdcaf92bb9996ff2899ef77e
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_Chrna6\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	C1QL3 SLC26A4 SGPP2	3.96e-04	125	51	3	fac8a9bff83abb8976013ff7d2b4ce0b68fbb70a
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC7A2 PLEKHH2 SDK1	3.96e-04	125	51	3	b162a5bfbb8ac5e65e13578fef9de442a9e4fd8b
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGPP2 RFX3 GABRA2	3.96e-04	125	51	3	35042ed43045dddc341b76cc5f9fe31b5ba0abb8
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGPP2 RFX3 GABRA2	4.05e-04	126	51	3	4eeea015efe17e0aae5bd76b71fa70b5149dfada
ToppCell	droplet-Lung-1m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l14\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPAG1 LYST EIF2AK3	4.64e-04	132	51	3	14a512f433315892bf0326419f23d0d5919d01ec
ToppCell	facs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC7A3 IGDCC3 ROS1	5.62e-04	141	51	3	4aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCell	facs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC7A3 IGDCC3 ROS1	5.62e-04	141	51	3	e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCell	facs-Heart-Unknown-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC7A3 IGDCC3 ROS1	5.74e-04	142	51	3	759fbbd15b4fb313bd6269b7f087edafebd530ef
ToppCell	E12.5-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CFAP47 SPAG1 LMNB1	5.86e-04	143	51	3	cc396b81a5e47d78c2d1cb49d682391376b63476
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	C1QL3 SLC26A4 GABRA2	5.86e-04	143	51	3	5fb5a4ea93e5cce55d427e3b4a50a979504fad3c
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MS4A4A SLC7A2 LDLRAD3	5.97e-04	144	51	3	f769be4da268980ea7c06d7097ec39d06777e675
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Gkn1_Pcdh19\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	C1QL3 SLC26A4 MEI1	5.97e-04	144	51	3	e8caeb6485f4c8f9a3384570dc69024c2bcc9ab0
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_ALM_Tgfb1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	C1QL3 SLC26A4 MEI1	6.10e-04	145	51	3	84d50a13b48d50c16e768422908e371a55972d0e
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PLEKHH2 REEP2 CFB	6.22e-04	146	51	3	cffa91d76606f74553d81150adbb23b003746316
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Col18a1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	C1QL3 SLC26A4 LDLRAD3	6.47e-04	148	51	3	fc80c02b51cf55a04ce550838ee2f41d8f656f41
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SGPP2 SDK1 CFB	6.99e-04	152	51	3	eee86b508b8f140ea44e21d8c04c409a7b689e39
Computational	Actin cytoskeleton binding.	FLNB FLNC WDR1	1.01e-04	30	33	3	MODULE_524
Computational	Genes in the cancer module 419.	FLNB FLNC WDR1	1.48e-04	34	33	3	MODULE_419
Drug	L-Lysine	SLC7A1 SLC7A2 SLC7A3	9.93e-08	5	50	3	DB00123
Drug	L-Ornithine	SLC7A1 SLC7A2 SLC7A3	3.57e-06	14	50	3	DB00129
Drug	naBE	SLC7A1 SLC7A2 SLC7A3	6.63e-06	17	50	3	CID000151475
Drug	flunitrazepam	SLC6A1 FBLN5 SLC7A3 GABRA2	8.57e-06	59	50	4	CID000003380
Disease	myofibrillar myopathy 5 (implicated_via_orthology)	FLNB FLNC	8.43e-06	3	50	2	DOID:0080096 (implicated_via_orthology)
Disease	distal muscular dystrophy 4 (implicated_via_orthology)	FLNB FLNC	8.43e-06	3	50	2	DOID:0111190 (implicated_via_orthology)
Disease	myopathy (implicated_via_orthology)	FLNB FLNC LMNB1	7.50e-05	48	50	3	DOID:423 (implicated_via_orthology)
Disease	Libman-Sacks Disease	PCNX3 CR2 CFB	1.32e-04	58	50	3	C0242380
Disease	Lupus Erythematosus, Systemic	PCNX3 CR2 CFB	2.41e-04	71	50	3	C0024141
Disease	Age-related macular degeneration	FBLN5 CFB	4.23e-04	18	50	2	cv:C0242383
Disease	pulse pressure measurement	HGFAC FLNB FBLN5 OLFM3 PIK3C2A WDR1 MEI1 SNX19 CFB	4.91e-04	1392	50	9	EFO_0005763
Disease	fibrinogen measurement	MS4A4A HGFAC OLFM3	8.47e-04	109	50	3	EFO_0004623
Disease	lymphocyte measurement	SLC7A1 ERN1 LMNB1	1.04e-03	117	50	3	EFO_0803546
Disease	Age related macular degeneration	FBLN5 CFB	1.19e-03	30	50	2	C0242383

Protein segments in the cluster

Peptide	Gene	Start	Entry
TYEYSSPYVTAPSKA	CCDC7	1301	Q96M83
SPYVTAPSKAIYRTY	CCDC7	1306	Q96M83
TTYGLSAYSGKVRYI	EIF2AK3	201	Q9NZJ5
ISAATYSTVPKIAFY	C1QL3	116	Q5VWW1
ARVPKTGSAYLYTYV	SLC7A2	91	P52569
VRVFKIYLTASYTYP	ABHD16B	11	Q9H3Z7
KTVGYVSAGTVEYLY	ACACB	556	O00763
ASYGVKPRYGLVTYA	CFB	301	P00751
AYAYTGKLTLSLYTI	KLHL31	126	Q9H511
LVYYPSITYAIIGSS	LDLRAD3	166	Q86YD5
TYISASPASTVYTGY	HIPK2	1171	Q9H2X6
STAYSFYIKAYTPRG	IGDCC3	491	Q8IVU1
GDTSVSYKYTSRYVL	LMNB1	476	P20700
PLKFGSYAYTTSEVT	GABRA2	181	P47869
TYDIFYTAAKPGTYV	FLNB	1671	O75369
YTAAKPGTYVIYVRF	FLNB	1676	O75369
TYYVKSIIYYVSRSP	PCNX3	1486	Q9H6A9
TYALPSIYPSTYSKQ	PIK3C2A	151	O00443
YSGSTYYNPSLKSRV	IGHV4-39	81	P01824
YSPAFPGTYTITIKY	FLNC	1216	Q14315
SVYSKQPYTEYISTR	MOK	151	Q9UQ07
TFGIEKYIPYTLYSV	HGFAC	476	Q04756
LSYTTSGLYTSLIYK	PLEKHH2	581	Q8IVE3
ASVCYLYGKLYSSPV	MEI1	196	Q5TIA1
SYEKYGTIVIQYVFP	DTX3	231	Q8N9I9
YYSTPIAVGTVIRYS	CR2	36	P20023
TPTLYVGKYSTSLYA	ERN1	281	O75460
KYCTVVAYPTDLYTI	BRWD1	1196	Q9NSI6
LSVVYTTYCPAQYTI	LYST	1741	Q99698
TYGSNPISVYIGYTI	MS4A4A	91	Q96JQ5
TTRYPGAYYIFQIKS	FBLN5	371	Q9UBX5
TTYSSEYKYIIPSLQ	SDK1	146	Q7Z5N4
TVSYTTEVSLPKYFY	CFAP47	2236	Q6ZTR5
VPRSGSAYLYSYVTV	SLC7A3	91	Q8WY07
LTGAKVYYSYSTKTS	OLFM3	411	Q96PB7
TGKVVYFSATYPYIM	SLC6A1	236	P30531
VLESGVSPGKYYTYA	TRGV2	76	A0A075B6R0
VYTNGAIRTTTYPYT	RFX3	66	P48380
KITGYIIYYSTDVNA	NEO1	986	Q92859
SKGATVYSPSRYSYQ	SETD5	1226	Q9C0A6
VVVAKYAPSGFYIAS	WDR1	61	O75083
VPYKFVTYTSVGICA	SGPP2	371	Q8IWX5
RVPKTTGSAYTYSYV	SLC7A14	111	Q8TBB6
IKTYTGPFVYYVKST	SPATA2	111	Q9UM82
VLIFGTLYPAYSSYK	REEP2	11	Q9BRK0
YAIAVSVGKVYATKY	SLC26A4	361	O43511
VPKTGSAYLYSYVTV	SLC7A1	91	P30825
YYTRSISALPTVVAY	SPAG1	231	Q07617
PYTSYNVRVVVVYKT	ROS1	1721	P08922
TTVIPRVYTYYVSTV	TMEM165	151	Q9HC07
GTGFHPYTLYTVKYE	SNX19	546	Q92543
TPFYADSLVGTYSKI	ROCK1	276	Q13464
RYYSKVTPSYDATAV	SOHLH2	366	Q9NX45