Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transporter activity	ABCA1 CALHM5 GJE1 KCNU1 SLC2A7 GRAMD1A SLC35A2 SLC49A4 TMC4 ABCD1 ATG9A SLC16A12 SLC35A5	9.49e-05	1289	60	13	GO:0005215
GeneOntologyMolecularFunction	pyrimidine nucleotide-sugar transmembrane transporter activity	SLC35A2 SLC35A5	4.80e-04	11	60	2	GO:0015165
GeneOntologyMolecularFunction	transmembrane transporter activity	ABCA1 CALHM5 GJE1 KCNU1 SLC2A7 SLC35A2 SLC49A4 TMC4 ABCD1 SLC16A12 SLC35A5	6.92e-04	1180	60	11	GO:0022857
GeneOntologyMolecularFunction	carbohydrate derivative transmembrane transporter activity	SLC35A2 ABCD1 SLC35A5	7.44e-04	59	60	3	GO:1901505
GeneOntologyMolecularFunction	nucleobase-containing compound transmembrane transporter activity	SLC35A2 ABCD1 SLC35A5	7.44e-04	59	60	3	GO:0015932
GeneOntologyMolecularFunction	nucleotide-sugar transmembrane transporter activity	SLC35A2 SLC35A5	7.89e-04	14	60	2	GO:0005338
GeneOntologyBiologicalProcess	endomembrane system organization	EMC6 SEC16B ABCA1 NBEAL2 SPTB SNX10 ABCD1 ATG9A PLEC FER1L5	1.87e-05	672	59	10	GO:0010256
GeneOntologyCellularComponent	endoplasmic reticulum membrane	EMC6 SEC16B HSD3B7 ABCA1 SRD5A3 CPT1C GRAMD1A SYNE2 SLC35A2 SREBF1 DIPK1B ALG3 ABCD1 ATG9A	1.07e-05	1293	59	14	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	EMC6 SEC16B HSD3B7 ABCA1 SRD5A3 CPT1C GRAMD1A SYNE2 SLC35A2 SREBF1 DIPK1B ALG3 ABCD1 ATG9A	1.13e-05	1299	59	14	GO:0098827
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	EMC6 SEC16B HSD3B7 ABCA1 SRD5A3 CPT1C GRAMD1A SYNE2 SLC35A2 SREBF1 DIPK1B ALG3 ABCD1 ATG9A	1.44e-05	1327	59	14	GO:0042175
GeneOntologyCellularComponent	apical cytoplasm	VANGL2 SNX10	4.68e-05	4	59	2	GO:0090651
MousePheno	small pacinian corpuscles	ETV1 ETV4	1.01e-05	2	45	2	MP:0030998
MousePheno	decreased pacinian corpuscle number	ETV1 ETV4	1.01e-05	2	45	2	MP:0030996
MousePheno	abnormal pacinian corpuscle morphology	ETV1 ETV4	1.01e-05	2	45	2	MP:0000988
MousePheno	abnormal cutaneous/subcutaneous mechanoreceptor morphology	ETV1 ETV4	1.01e-04	5	45	2	MP:0000973
Domain	DUF3669_Znf	ZNF398 ZNF282 ZNF783	5.65e-07	6	58	3	IPR022137
Domain	DUF3669	ZNF398 ZNF282 ZNF783	5.65e-07	6	58	3	PF12417
Domain	ETS_PEA3_N	ETV1 ETV4	2.84e-05	3	58	2	PF04621
Domain	ETS_PEA3_N	ETV1 ETV4	2.84e-05	3	58	2	IPR006715
Domain	Actinin_actin-bd_CS	SPTB SYNE2 PLEC	4.82e-05	23	58	3	IPR001589
Domain	ACTININ_2	SPTB SYNE2 PLEC	4.82e-05	23	58	3	PS00020
Domain	ACTININ_1	SPTB SYNE2 PLEC	4.82e-05	23	58	3	PS00019
Domain	Nuc_sug_transpt	SLC35A2 SLC35A5	9.42e-05	5	58	2	IPR007271
Domain	Nuc_sug_transp	SLC35A2 SLC35A5	9.42e-05	5	58	2	PF04142
Domain	Spectrin_repeat	SPTB SYNE2 PLEC	9.81e-05	29	58	3	IPR002017
Domain	Spectrin/alpha-actinin	SPTB SYNE2 PLEC	1.32e-04	32	58	3	IPR018159
Domain	SPEC	SPTB SYNE2 PLEC	1.32e-04	32	58	3	SM00150
Domain	CH	SPTB SYNE2 PLEC	1.08e-03	65	58	3	SM00033
Domain	CH	SPTB SYNE2 PLEC	1.34e-03	70	58	3	PF00307
Domain	-	SPTB SYNE2 PLEC	1.40e-03	71	58	3	1.10.418.10
Domain	CH	SPTB SYNE2 PLEC	1.52e-03	73	58	3	PS50021
Domain	CH-domain	SPTB SYNE2 PLEC	1.64e-03	75	58	3	IPR001715
Domain	Spectrin	SPTB SYNE2	2.30e-03	23	58	2	PF00435
Domain	Ets	ETV1 ETV4	3.40e-03	28	58	2	PF00178
Domain	ETS_DOMAIN_1	ETV1 ETV4	3.40e-03	28	58	2	PS00345
Domain	ETS_DOMAIN_2	ETV1 ETV4	3.40e-03	28	58	2	PS00346
Domain	ETS	ETV1 ETV4	3.40e-03	28	58	2	SM00413
Domain	Ets_dom	ETV1 ETV4	3.40e-03	28	58	2	IPR000418
Domain	ETS_DOMAIN_3	ETV1 ETV4	3.40e-03	28	58	2	PS50061
Domain	MFS	SLC2A7 SLC49A4 SLC16A12	4.61e-03	108	58	3	PS50850
Domain	ABC_transporter_CS	ABCA1 ABCD1	7.54e-03	42	58	2	IPR017871
Domain	MFS_dom	SLC2A7 SLC49A4 SLC16A12	8.36e-03	134	58	3	IPR020846
Domain	ABC_TRANSPORTER_2	ABCA1 ABCD1	9.76e-03	48	58	2	PS50893
Domain	ABC_tran	ABCA1 ABCD1	9.76e-03	48	58	2	PF00005
Domain	ABC_TRANSPORTER_1	ABCA1 ABCD1	1.02e-02	49	58	2	PS00211
Domain	ABC_transporter-like	ABCA1 ABCD1	1.06e-02	50	58	2	IPR003439
Pubmed	Oleic acid modulates mRNA expression of liver X receptor (LXR) and its target genes ABCA1 and SREBP1c in human neutrophils.	ABCA1 SREBF1	2.93e-06	2	60	2	24722912
Pubmed	Specific and redundant activities of ETV1 and ETV4 in prostate cancer aggressiveness revealed by co-overexpression cellular contexts.	ETV1 ETV4	2.93e-06	2	60	2	25595908
Pubmed	ETV1, 4 and 5: an oncogenic subfamily of ETS transcription factors.	ETV1 ETV4	8.77e-06	3	60	2	22425584
Pubmed	PEA3 transcription factors are expressed in tissues undergoing branching morphogenesis and promote formation of duct-like structures by mammary epithelial cells in vitro.	ETV1 ETV4	8.77e-06	3	60	2	12871699
Pubmed	Novel RNA hybridization method for the in situ detection of ETV1, ETV4, and ETV5 gene fusions in prostate cancer.	ETV1 ETV4	8.77e-06	3	60	2	25203299
Pubmed	The role of Pea3 group transcription factors in esophageal squamous cell carcinoma.	ETV1 ETV4	8.77e-06	3	60	2	21689625
Pubmed	Open chromatin profiling identifies AP1 as a transcriptional regulator in oesophageal adenocarcinoma.	ETV1 ETV4	8.77e-06	3	60	2	28859074
Pubmed	Expression patterns of the Ets transcription factors from the PEA3 group during early stages of mouse development.	ETV1 ETV4	8.77e-06	3	60	2	11578874
Pubmed	ETS transcription factor ER81 is required for the Pacinian corpuscle development.	ETV1 ETV4	8.77e-06	3	60	2	16493690
Pubmed	Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETS factors ETV1, ETV4 and ETV5.	ETV1 ETV4	8.77e-06	3	60	2	28161714
Pubmed	PEA3/ETV4-related transcription factors coupled with active ERK signalling are associated with poor prognosis in gastric adenocarcinoma.	ETV1 ETV4	8.77e-06	3	60	2	21673681
Pubmed	Differential expression patterns of the PEA3 group transcription factors through murine embryonic development.	ETV1 ETV4	8.77e-06	3	60	2	9285689
Pubmed	Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo.	ETV1 ETV4	1.75e-05	4	60	2	20517297
Pubmed	The E3 ubiquitin ligase complex component COP1 regulates PEA3 group member stability and transcriptional activity.	ETV1 ETV4	1.75e-05	4	60	2	20062082
Pubmed	β-Cell Insulin Secretion Requires the Ubiquitin Ligase COP1.	ETV1 ETV4	1.75e-05	4	60	2	26627735
Pubmed	Clonal evaluation of early onset prostate cancer by expression profiling of ERG, SPINK1, ETV1, and ETV4 on whole-mount radical prostatectomy tissue.	ETV1 ETV4	1.75e-05	4	60	2	31584209
Pubmed	ETS (E26 transformation-specific) up-regulation of the transcriptional co-activator TAZ promotes cell migration and metastasis in prostate cancer.	ETV1 ETV4	1.75e-05	4	60	2	28408625
Pubmed	Pea3 transcription factor family members Etv4 and Etv5 mediate retrograde signaling and axonal growth of DRG sensory neurons in response to NGF.	ETV1 ETV4	1.75e-05	4	60	2	24089499
Pubmed	Promoter-specific roles for liver X receptor/corepressor complexes in the regulation of ABCA1 and SREBP1 gene expression.	ABCA1 SREBF1	1.75e-05	4	60	2	12897148
Pubmed	Detection of the TMPRSS2-ETS fusion gene in prostate carcinomas: retrospective analysis of 55 formalin-fixed and paraffin-embedded samples with clinical data.	ETV1 ETV4	1.75e-05	4	60	2	18474293
Pubmed	The impact of severe LDL receptor mutations on SREBP-pathway regulation in homozygous familial hypercholesterolemia (FH).	ABCA1 SREBF1	2.92e-05	5	60	2	22425645
Pubmed	Methyl protodioscin increases ABCA1 expression and cholesterol efflux while inhibiting gene expressions for synthesis of cholesterol and triglycerides by suppressing SREBP transcription and microRNA 33a/b levels.	ABCA1 SREBF1	2.92e-05	5	60	2	25733328
Pubmed	An Interaction with Ewing's Sarcoma Breakpoint Protein EWS Defines a Specific Oncogenic Mechanism of ETS Factors Rearranged in Prostate Cancer.	ETV1 ETV4	2.92e-05	5	60	2	27783944
Pubmed	Onset of ETS expression is not accelerated by premature exposure to signals from limb mesenchyme.	ETV1 ETV4	2.92e-05	5	60	2	17654714
Pubmed	KLF15 Enables Rapid Switching between Lipogenesis and Gluconeogenesis during Fasting.	ABCA1 SREBF1	4.37e-05	6	60	2	27545894
Pubmed	Pea3 transcription factor cooperates with USF-1 in regulation of the murine bax transcription without binding to an Ets-binding site.	ETV1 ETV4	4.37e-05	6	60	2	15466854
Pubmed	TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton.	SYNE2 PLEC	4.37e-05	6	60	2	18827015
Pubmed	Target-induced transcriptional control of dendritic patterning and connectivity in motor neurons by the ETS gene Pea3.	ETV1 ETV4	6.11e-05	7	60	2	17190606
Pubmed	The Pea3 Ets transcription factor regulates differentiation of multipotent progenitor cells during mammary gland development.	ETV1 ETV4	6.11e-05	7	60	2	18977342
Pubmed	Congenital Disorders of N-Linked Glycosylation and Multiple Pathway Overview	SRD5A3 SLC35A2 ALG3	6.15e-05	44	60	3	20301507
Pubmed	Peripheral NT3 signaling is required for ETS protein expression and central patterning of proprioceptive sensory afferents.	ETV1 ETV4	8.14e-05	8	60	2	12741988
Pubmed	Sterol-responsive element-binding protein (SREBP) 2 down-regulates ATP-binding cassette transporter A1 in vascular endothelial cells: a novel role of SREBP in regulating cholesterol metabolism.	ABCA1 SREBF1	8.14e-05	8	60	2	15358760
Pubmed	COP1 is a tumour suppressor that causes degradation of ETS transcription factors.	ETV1 ETV4	8.14e-05	8	60	2	21572435
Pubmed	Runx3 controls the axonal projection of proprioceptive dorsal root ganglion neurons.	ETV1 ETV4	8.14e-05	8	60	2	12352981
Pubmed	Positional differences of axon growth rates between sensory neurons encoded by Runx3.	ETV1 ETV4	1.05e-04	9	60	2	22903063
Pubmed	Early motor neuron pool identity and muscle nerve trajectory defined by postmitotic restrictions in Nkx6.1 activity.	ETV1 ETV4	1.05e-04	9	60	2	18215620
Pubmed	Plasticity within the niche ensures the maintenance of a Sox2+ stem cell population in the mouse incisor.	VANGL2 LGR5	1.05e-04	9	60	2	29180573
Pubmed	Laminar patterning in the developing neocortex by temporally coordinated fibroblast growth factor signaling.	ETV1 ETV4	1.31e-04	10	60	2	15470137
Pubmed	Cytoskeletal disruption and small heat shock protein translocation immediately after lengthening contractions.	SPTB PLEC	1.31e-04	10	60	2	14627610
Pubmed	Etv1 inactivation reveals proprioceptor subclasses that reflect the level of NT3 expression in muscle targets.	ETV1 ETV4	1.31e-04	10	60	2	23522042
Pubmed	Expression of dopamine pathway genes in the midbrain is independent of known ETS transcription factor activity.	ETV1 ETV4	1.59e-04	11	60	2	20610757
Pubmed	Metabolic-stress-induced rearrangement of the 14-3-3ζ interactome promotes autophagy via a ULK1- and AMPK-regulated 14-3-3ζ interaction with phosphorylated Atg9.	AKAP13 ATG9A	1.59e-04	11	60	2	25266655
Pubmed	Emx2 patterns the neocortex by regulating FGF positional signaling.	ETV1 ETV4	1.59e-04	11	60	2	12872126
Pubmed	Coordination of epithelial branching and salivary gland lumen formation by Wnt and FGF signals.	ETV1 ETV4	1.59e-04	11	60	2	21806977
Pubmed	Inactivation of Capicua in adult mice causes T-cell lymphoblastic lymphoma.	ETV1 ETV4	1.59e-04	11	60	2	28827401
Pubmed	ETS gene Er81 controls the formation of functional connections between group Ia sensory afferents and motor neurons.	ETV1 ETV4	1.91e-04	12	60	2	10850491
Pubmed	p63 Transcription Factor Regulates Nuclear Shape and Expression of Nuclear Envelope-Associated Genes in Epidermal Keratinocytes.	SYNE2 PLEC	1.91e-04	12	60	2	28595999
Pubmed	Genome-wide meta-analysis identifies variants associated with platinating agent susceptibility across populations.	AKAP13 LILRB4	2.26e-04	13	60	2	21844884
Pubmed	Role of Fgf8 signalling in the specification of rostral Cajal-Retzius cells.	ETV1 ETV4	2.26e-04	13	60	2	20040495
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	RALGAPA1 VPS13D GRAMD1A SYNE2 SLC35A2 ATG9A	2.32e-04	504	60	6	34432599
Pubmed	Sprouty2-modulated Kras signaling rescues Shp2 deficiency during lens and lacrimal gland development.	ETV1 ETV4	2.63e-04	14	60	2	20215346
Pubmed	Function of PEA3 Ets transcription factors in mammary gland development and oncogenesis.	ETV1 ETV4	2.63e-04	14	60	2	14635793
Pubmed	Ubiquitin ligase COP1 coordinates transcriptional programs that control cell type specification in the developing mouse brain.	ETV1 ETV4	3.46e-04	16	60	2	30322923
Pubmed	New gene functions in megakaryopoiesis and platelet formation.	FAR2 PLEC EXOC3L2	3.78e-04	81	60	3	22139419
Pubmed	Hoxc10 and Hoxd10 regulate mouse columnar, divisional and motor pool identity of lumbar motoneurons.	ETV1 ETV4	3.91e-04	17	60	2	18065432
Pubmed	C/EBPbeta, when expressed from the C/ebpalpha gene locus, can functionally replace C/EBPalpha in liver but not in adipose tissue.	HPR SREBF1	3.91e-04	17	60	2	10982846
Pubmed	Phosphorylation of ETS1 by Src family kinases prevents its recognition by the COP1 tumor suppressor.	ETV1 ETV4	4.40e-04	18	60	2	25117710
Pubmed	Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum.	ETV1 GNAL	4.91e-04	19	60	2	10393115
Pubmed	Loss of Ataxin-1 Potentiates Alzheimer's Pathogenesis by Elevating Cerebral BACE1 Transcription.	ETV1 ETV4	4.91e-04	19	60	2	31442405
Pubmed	ATXN1 protein family and CIC regulate extracellular matrix remodeling and lung alveolarization.	ETV1 ETV4	4.91e-04	19	60	2	22014525
Pubmed	Biochemistry of mammalian peroxisomes revisited.	FAR2 ABCD1	5.45e-04	20	60	2	16756494
Pubmed	Requirement for the homeobox gene Hb9 in the consolidation of motor neuron identity.	ETV1 ETV4	5.45e-04	20	60	2	10482234
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	NBEAL2 SLC35A2 SREBF1 ZNF398 AKAP13 ABCD1 ATG9A PLEC	5.99e-04	1105	60	8	35748872
Pubmed	New BRAF knockin mice provide a pathogenetic mechanism of developmental defects and a therapeutic approach in cardio-facio-cutaneous syndrome.	ETV1 ETV4	6.02e-04	21	60	2	25035421
Pubmed	FGF-regulated Etv genes are essential for repressing Shh expression in mouse limb buds.	ETV1 ETV4	6.02e-04	21	60	2	19386269
Pubmed	mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells.	SPTB SYNE2 CAMTA2	6.61e-04	98	60	3	34943047
Pubmed	The interactome of KRAB zinc finger proteins reveals the evolutionary history of their functional diversification.	ZNF398 ZNF282	6.61e-04	22	60	2	31403225
Pubmed	Differential expression and function of ABCG1 and ABCG4 during development and aging.	ABCA1 SREBF1	6.61e-04	22	60	2	19633360
Pubmed	Repression of Fgf signaling by sprouty1-2 regulates cortical patterning in two distinct regions and times.	ETV1 ETV4	7.88e-04	24	60	2	20237272
Pubmed	Etv transcription factors functionally diverge from their upstream FGF signaling in lens development.	ETV1 ETV4	7.88e-04	24	60	2	32043969
Pubmed	FGF-induced Pea3 transcription factors program the genetic landscape for cell fate determination.	ETV1 ETV4	7.88e-04	24	60	2	30188892
Pubmed	ETS-dependent regulation of a distal Gata4 cardiac enhancer.	ETV1 ETV4	7.88e-04	24	60	2	22056786
Pubmed	A semaphorin code defines subpopulations of spinal motor neurons during mouse development.	ETV1 ETV4	7.88e-04	24	60	2	15869472
Pubmed	Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans.	ETV1 ETV4	8.56e-04	25	60	2	28288114
Pubmed	A census of human transcription factors: function, expression and evolution.	TGIF2LY SREBF1 ETV1 ZNF398 ETV4 CAMTA2 ZNF282	9.37e-04	908	60	7	19274049
Pubmed	The HIV matrix protein p17 induces hepatic lipid accumulation via modulation of nuclear receptor transcriptoma.	ABCA1 SREBF1	9.99e-04	27	60	2	26469385
Pubmed	Heparan Sulfate Biosynthesis Enzyme, Ext1, Contributes to Outflow Tract Development of Mouse Heart via Modulation of FGF Signaling.	ETV1 ETV4	9.99e-04	27	60	2	26295701
Pubmed	Fgf10 is required for specification of non-sensory regions of the cochlear epithelium.	ETV4 LGR5	1.15e-03	29	60	2	25624266
Pubmed	ETS-family genes in pancreatic development.	ETV1 ETV4	1.15e-03	29	60	2	17907201
Pubmed	Analysis of lipid pathway genes indicates association of sequence variation near SREBF1/TOM1L2/ATPAF2 with dementia risk.	ABCA1 SREBF1	1.15e-03	29	60	2	20167577
Pubmed	Murine chromosomal location of eight members of the hepatocyte nuclear factor 3/fork head winged helix family of transcription factors.	HPR SPTB	1.15e-03	29	60	2	7789972
Pubmed	GDE2 regulates subtype-specific motor neuron generation through inhibition of Notch signaling.	ETV1 ETV4	1.23e-03	30	60	2	21943603
Pubmed	Pharmacogenetic predictors of statin-mediated low-density lipoprotein cholesterol reduction and dose response.	ABCA1 SREBF1	1.32e-03	31	60	2	20031551
Pubmed	Alx4 relays sequential FGF signaling to induce lacrimal gland morphogenesis.	ETV1 ETV4	1.40e-03	32	60	2	29028795
Pubmed	Hox repertoires for motor neuron diversity and connectivity gated by a single accessory factor, FoxP1.	ETV1 ETV4	1.49e-03	33	60	2	18662545
Pubmed	The progenitor zone of the ventral medial ganglionic eminence requires Nkx2-1 to generate most of the globus pallidus but few neocortical interneurons.	ETV1 GNAL	1.58e-03	34	60	2	20181579
Pubmed	Negative regulation of Shh levels by Kras and Fgfr2 during hair follicle development.	ETV1 ETV4	1.58e-03	34	60	2	23123965
Interaction	ZNF767P interactions	ZNF398 ZNF282 ZNF783	1.17e-05	16	57	3	int:ZNF767P
Cytoband	7q36.1	ZNF398 ZNF282 ZNF783	1.29e-04	74	60	3	7q36.1
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	CPT1C IFNL4 GRAMD1A BCKDHA TMC4 EXOC3L2 LILRB4	9.10e-04	1192	60	7	chr19q13
Cytoband	1p36.22	MIIP VPS13D	1.09e-03	37	60	2	1p36.22
Cytoband	Ensembl 112 genes in cytogenetic band chr7q36	ZNF398 ZNF282 ZNF783	1.21e-03	159	60	3	chr7q36
Cytoband	17p13.2	EMC6 CAMTA2	2.39e-03	55	60	2	17p13.2
GeneFamily	Solute carriers	SLC2A7 SLC35A2 SLC49A4 SLC16A12 SLC35A5	1.70e-03	395	40	5	752
GeneFamily	ETS transcription factor family	ETV1 ETV4	1.74e-03	28	40	2	534
Coexpression	GSE9239_CTRL_VS_TNF_INHIBITOR_TREATED_DC_UP	NBEAL2 SLC49A4 SNX10 CTRC PLEC SLC16A12	5.89e-06	200	59	6	M6965
Coexpression	MILI_PSEUDOPODIA_HAPTOTAXIS_DN	TMPPE SRD5A3 SLC35A2 SLC49A4 SREBF1 ALG3 ARMC9 ATG9A PLEC	2.02e-05	681	59	9	M5314
Coexpression	MILI_PSEUDOPODIA_HAPTOTAXIS_DN	TMPPE SRD5A3 SLC35A2 SLC49A4 SREBF1 ALG3 ARMC9 ATG9A PLEC	2.59e-05	703	59	9	MM1055
ToppCell	Bronchial_Brush-Epithelial-Goblet_1\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	TMPPE HSD3B7 ABCA1 BCKDHA IL23A	2.42e-06	159	60	5	a8fa49dc2e6ad726d1f4f2b30693fecd1151a485
ToppCell	Bronchial_Brush-Epithelial-Goblet_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	TMPPE HSD3B7 ABCA1 BCKDHA IL23A	2.42e-06	159	60	5	95834b767cfb4fb8c5aeea89c10f3e14a1fd15c1
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Classical_Monocyte-Mono_c1-CD14-CCL3\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ABCA1 GRAMD1A SNX10 CARD16 LILRB4	4.20e-06	178	60	5	fbf49766e1504df554856b84c0576c06f3167329
ToppCell	wk_08-11-Hematologic-Myeloid-Promonocyte-like\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	FAR2 HPR SNX10 IL23A LILRB4	5.47e-06	188	60	5	2ae945d96a011f246d04a42bcd6ef443232b03f4
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Vein\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	RALGAPA1 FAR2 GRAMD1A PLEC EXOC3L2	7.22e-06	199	60	5	cfb624c7728046fc7f3ef071f57e4d7b013f3fef
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Vein\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	RALGAPA1 FAR2 SYNE2 PLEC EXOC3L2	7.39e-06	200	60	5	7eb366b2c5394af7c77650bde6261e7dac67154e
ToppCell	10x5'-bone_marrow-Myeloid_Monocytic-Cycling_mono\|bone_marrow / Manually curated celltypes from each tissue	SLAMF9 HPR PLEC LILRB4	4.75e-05	148	60	4	de35eeefad0e27a0d127e2e4bedead2bddb75152
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage_3\|390C / Donor, Lineage, Cell class and subclass (all cells)	HSD3B7 SNX10 ABCD1 LILRB4	5.27e-05	152	60	4	f717aae4882e9b67e5e40f4ef5b0d35f74a89165
ToppCell	droplet-Fat-SCAT-30m-Myeloid\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLAMF9 CTRC ETV1 LILRB4	5.54e-05	154	60	4	73de626b210ec5482ba89a65e784c1e77ff2894e
ToppCell	droplet-Fat-SCAT-30m-Myeloid-myeloid_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLAMF9 CTRC ETV1 LILRB4	5.54e-05	154	60	4	56fe9953e58f71626d3ddf63d340ed35dfc4ce9f
ToppCell	390C-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	VANGL2 ZNF398 DIPK1B SLC35A5	6.75e-05	162	60	4	fbb0cc2b1434a340dc35058b77c73ea61004c252
ToppCell	390C-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	VANGL2 ZNF398 DIPK1B SLC35A5	6.75e-05	162	60	4	45be019b50e3727fc9d3fad2ff78e74e4f2d746b
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ABCA1 SREBF1 ZNF783 LILRB4	8.32e-05	171	60	4	87d652afbb375f8ee50e5faecf6085630cd2163c
ToppCell	droplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSD3B7 SLAMF9 SNX10 LILRB4	9.30e-05	176	60	4	e74ad0db3b05897edcfabeb11008ede2b9eeb638
ToppCell	droplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSD3B7 SLAMF9 SNX10 LILRB4	9.51e-05	177	60	4	71919b5c9bfa87fdd2cd44dfa057b66ea081be5d
ToppCell	droplet-Lung-30m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SRD5A3 FANCL ALG3 ARMC9	9.93e-05	179	60	4	af03705a783e77f75c44fdfa793cfdccbf9dd91c
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA1 SLAMF9 SNX10 CARD16	9.93e-05	179	60	4	b07ebfd4157ae7436f275add78f2ac9ffc55f417
ToppCell	PND10-Epithelial-Epithelial_Airway-Neurosecretory-PNEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SNX10 ETV4 XRCC3 SLC16A12	1.06e-04	182	60	4	1923932a9c60e9ec33db69ded441210d1fb07bec
ToppCell	facs-Heart-RA\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CALHM5 SLAMF9 AKAP13 LILRB4	1.06e-04	182	60	4	8292e8e8474c930ffb88cbab4f6ebdb6f58db645
ToppCell	PND10-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SNX10 ETV4 XRCC3 SLC16A12	1.06e-04	182	60	4	69ff652f74cc47fbe0bd665ab17c445c5b959dad
ToppCell	droplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSD3B7 ABCA1 SLAMF9 SNX10	1.13e-04	185	60	4	4bee178ede12f56ba5f5bec44a03dc2a62c50137
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_1\|390C / Donor, Lineage, Cell class and subclass (all cells)	VPS13D FAR2 SLC49A4 CTRC	1.15e-04	186	60	4	064b6047215597465bb51a8a1547ef5a226552f9
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	VPS13D FAR2 SLC49A4 CTRC	1.20e-04	188	60	4	b1ec7c45aedcc3d22cac898c6a3679e7f8b44c77
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_1\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	VPS13D FAR2 SLC49A4 CTRC	1.20e-04	188	60	4	2c4e791df69a9df29922f9117e5cac7787c129ce
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA1 SNX10 CARD16 LILRB4	1.33e-04	193	60	4	50c2832de75b6469f649355c6b9a75e910d32db3
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA1 SNX10 CARD16 LILRB4	1.33e-04	193	60	4	222829c30ebe47f0ed1e035897e3cd4be10b2a11
ToppCell	(07)_Brush\|World / shred by cell type and Timepoint	SPTB A3GALT2 ETV1 LGR5	1.33e-04	193	60	4	9af9d22a130ff97a9c37142a65e841b056d08640
ToppCell	Control-Myeloid-TRAM2\|Control / Condition, Lineage and Cell class	ABCA1 GRAMD1A SNX10 LILRB4	1.35e-04	194	60	4	d951dd1274d3ff1ac30671ec4153a4a8bc97b53f
ToppCell	3'-Distal_airway-Immune_Myeloid\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA1 SNX10 CARD16 LILRB4	1.38e-04	195	60	4	4df004b8ca7669a57d85c6dffef5b82b4ea1dfdf
ToppCell	wk_08-11-Hematologic-Myeloid-Myelocyte-like\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	FAR2 HPR SNX10 SREBF1	1.41e-04	196	60	4	4b88c96b737a747422674ad99c073b28e6febc7c
ToppCell	Macrophages-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	HSD3B7 ABCA1 SLAMF9 LILRB4	1.41e-04	196	60	4	861c402ed8b8fde3582cc777c1357b45f5a2489b
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	HSD3B7 ABCA1 SNX10 LILRB4	1.44e-04	197	60	4	1ded28732ea5d1f9ebca0b136575103540600ff1
ToppCell	Macrophages-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	HSD3B7 SNX10 CARD16 LILRB4	1.44e-04	197	60	4	598fb7a9a8400af49d90807b3155d3cc1c34f505
ToppCell	10x3'2.3-week_17-19-Myeloid_neutrophil-granulo-neutrophil-myelocyte\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	FAR2 HPR SYNE2 SNX10	1.46e-04	198	60	4	3bc05b8d97a7219af40db7a11aa271f02e74fca5
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_Inf._Macrophages\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	SLAMF9 SNX10 IL23A LILRB4	1.46e-04	198	60	4	ebc064dede536eda7715af0675fd4e657ff4ac5d
ToppCell	Bronchial-10x5prime-Immune_Myeloid-Macrophage_other-Macro_CHIT1\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	HSD3B7 ABCA1 SNX10 LILRB4	1.49e-04	199	60	4	54a54ad983503ed515d476882d86b17d97892037
ToppCell	Parenchymal-10x5prime-Immune_Myeloid-Macrophage_other-Macro_CHIT1\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA1 SLAMF9 SNX10 LILRB4	1.49e-04	199	60	4	f987f48970aec46156b80656e49b9f3604f3758c
ToppCell	Bronchus_Control_(B.)-Immune-TX-MoAM-1\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	ABCA1 SNX10 CARD16 LILRB4	1.52e-04	200	60	4	fe7f8b04067b6680b69c8523f0fa514ef97207e2
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SEC16B AKAP13 PLEC LILRB4	1.52e-04	200	60	4	80e0483d5ab0c6213aae0ec62619f57e6ec0e4c2
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal-Intermediate\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	SPTB LGR5 ZNF282 ZNF783	1.52e-04	200	60	4	a3fcd901cb281920f1bafdfd676399a6dc37355e
ToppCell	Substantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	INSL6 SLC2A7 IL23A	1.72e-04	80	60	3	0d02b242164d27f38f70ed77b106612fc7a3abca
ToppCell	Substantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr-Polydendrocyte.Tnr.Tmem2_(Tmem2)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	INSL6 SLC2A7 IL23A	1.72e-04	80	60	3	b95e4456adb7f7d42825351f010376c10bb35380
ToppCell	Substantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_2\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	INSL6 SLC2A7 IL23A	1.72e-04	80	60	3	313344cf7309bc17ca131b92a91b24489df577e2
Drug	Azlocillin sodium salt [37091-65-9]; Down 200; 8.2uM; MCF7; HT_HG-U133A	MIIP SRD5A3 NBEAL2 SLC35A2 AKAP13 ARMC9 ZNF783	5.78e-07	196	57	7	3468_DN
Drug	Pregnenolone [145-13-1]; Down 200; 12.6uM; PC3; HT_HG-U133A	MIIP ABCA1 VPS13D SLC35A2 ETV1 AKAP13	9.50e-06	196	57	6	4218_DN
Drug	Ketorolac tromethamine [74103-07-4]; Up 200; 10.6uM; PC3; HT_HG-U133A	VPS13D ETV1 AKAP13 ASPSCR1 XRCC3 ZNF783	9.77e-06	197	57	6	7286_UP
Drug	Vinpocetine [42971-09-5]; Down 200; 11.4uM; PC3; HT_HG-U133A	MIIP ABCA1 VPS13D BCKDHA IL23A ZNF282	1.04e-05	199	57	6	5859_DN
Drug	Maprotiline hydrochloride [10347-81-6]; Down 200; 12.8uM; PC3; HT_HG-U133A	VPS13D NBEAL2 ASPSCR1 CAMTA2 GNAL XRCC3	1.07e-05	200	57	6	6676_DN
Drug	SB-C	ABCA1 ETV4 AKAP13 FANCL	2.70e-05	69	57	4	CID005331010
Drug	GSK 3987	ABCA1 SREBF1	6.13e-05	5	57	2	ctd:C504517
Drug	sodium cholate	HSD3B7 ABCA1 SLC35A2 SREBF1 CARD16 ABCD1 PLEC	6.89e-05	408	57	7	CID000000303
Drug	atheronal-A	ABCA1 SREBF1	9.18e-05	6	57	2	ctd:C512174
Drug	Terfenadine [50679-08-8]; Down 200; 8.4uM; MCF7; HT_HG-U133A	VPS13D SRD5A3 ARMC9 PLEC ZNF783	1.16e-04	191	57	5	2227_DN
Drug	Cyclobenzaprine hydrochloride [6202-23-9]; Up 200; 12.8uM; HL60; HT_HG-U133A	ABCA1 NBEAL2 ASPSCR1 ABCD1 ZNF783	1.19e-04	192	57	5	1332_UP
Drug	felodipine; Down 200; 10uM; MCF7; HT_HG-U133A_EA	SREBF1 ASPSCR1 ARMC9 CAMTA2 PLEC	1.22e-04	193	57	5	965_DN
Drug	Benzthiazide [91-33-8]; Down 200; 9.2uM; MCF7; HT_HG-U133A	MIIP SRD5A3 SLC35A2 PLEC XRCC3	1.25e-04	194	57	5	4952_DN
Drug	Glycocholic acid [475-31-0]; Down 200; 8.6uM; MCF7; HT_HG-U133A	MIIP NBEAL2 AKAP13 CAMTA2 ZNF282	1.25e-04	194	57	5	5316_DN
Drug	Racecadotril [81110-73-8]; Down 200; 10.4uM; PC3; HT_HG-U133A	RALGAPA1 VPS13D SRD5A3 ETV1 ASPSCR1	1.25e-04	194	57	5	5755_DN
Drug	Fenspiride hydrochloride [5053-08-7]; Up 200; 13.4uM; HL60; HG-U133A	MIIP VPS13D NBEAL2 SPTB ASPSCR1	1.25e-04	194	57	5	1422_UP
Drug	Levocabastine hydrochloride [79547-78-7]; Down 200; 8.8uM; MCF7; HT_HG-U133A	ASPSCR1 ABCD1 PLEC XRCC3 ZNF282	1.25e-04	194	57	5	3509_DN
Drug	Clomiphene citrate (Z,E) [50-41-9]; Down 200; 6.6uM; HL60; HT_HG-U133A	ABCA1 VPS13D CAMTA2 ABCD1 ATG9A	1.28e-04	195	57	5	1269_DN
Drug	propacetamol	SLC35A2 ABCD1	1.28e-04	7	57	2	CID000068865
Drug	Alverine citrate salt [5560-59-8]; Down 200; 8.4uM; PC3; HT_HG-U133A	SLC35A2 ARMC9 CAMTA2 ABCD1 ZNF282	1.31e-04	196	57	5	2110_DN
Drug	Metampicillin sodium salt [6489-61-8]; Up 200; 10.4uM; HL60; HG-U133A	MIIP NBEAL2 AKAP13 XRCC3 ZNF783	1.31e-04	196	57	5	1440_UP
Drug	estradiol, USP; Down 200; 0.01uM; MCF7; HT_HG-U133A_EA	SLC35A2 ASPSCR1 ABCD1 PLEC XRCC3	1.31e-04	196	57	5	1021_DN
Drug	Epivincamine [6835-99-0]; Down 200; 11.2uM; MCF7; HT_HG-U133A	NBEAL2 AKAP13 ABCD1 XRCC3 ZNF783	1.31e-04	196	57	5	2775_DN
Drug	Riboflavine [83-88-5]; Up 200; 10.6uM; HL60; HG-U133A	MIIP VPS13D SLC35A2 AKAP13 PLEC	1.34e-04	197	57	5	1767_UP
Drug	Dydrogesterone [152-62-5]; Up 200; 12.8uM; HL60; HT_HG-U133A	ABCA1 VPS13D SPTB SYNE2 SREBF1	1.34e-04	197	57	5	2156_UP
Drug	Meticrane [1084-65-7]; Down 200; 14.6uM; PC3; HT_HG-U133A	SNX10 ETV1 PLEC IL23A ZNF282	1.34e-04	197	57	5	1792_DN
Drug	Triprolidine hydrochloride [550-70-9]; Down 200; 12.8uM; PC3; HT_HG-U133A	VPS13D SYNE2 SLC35A2 ETV1 BCKDHA	1.34e-04	197	57	5	7248_DN
Drug	thioridazine hydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A	ASPSCR1 ARMC9 PLEC XRCC3 ZNF783	1.34e-04	197	57	5	5227_DN
Drug	Coralyne chloride hydrate [38989-38-7]; Down 200; 9.6uM; PC3; HT_HG-U133A	MIIP ABCA1 SLC35A2 AKAP13 BCKDHA	1.34e-04	197	57	5	6317_DN
Drug	Gallamine triethiodide [65-29-2]; Down 200; 4.4uM; PC3; HT_HG-U133A	RALGAPA1 VPS13D SRD5A3 ETV1 ZNF783	1.34e-04	197	57	5	5735_DN
Drug	Viomycin sulfate [37883-00-4]; Up 200; 5.2uM; PC3; HT_HG-U133A	MIIP RALGAPA1 ABCA1 SLC35A2 ASPSCR1	1.37e-04	198	57	5	7278_UP
Drug	Sulfamethizole [144-82-1]; Down 200; 14.8uM; PC3; HT_HG-U133A	MIIP VPS13D SRD5A3 ETV1 AKAP13	1.37e-04	198	57	5	5798_DN
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A	MIIP NBEAL2 CAMTA2 PLEC XRCC3	1.37e-04	198	57	5	1650_DN
Drug	Proxyphylline [603-00-9]; Down 200; 16.8uM; HL60; HT_HG-U133A	MIIP ETV1 ASPSCR1 ARMC9 PLEC	1.40e-04	199	57	5	3115_DN
Drug	Atropine-N-oxide hydrochloride [4574-60-1]; Up 200; 11.8uM; PC3; HT_HG-U133A	MIIP ABCA1 SRD5A3 ARMC9 XRCC3	1.40e-04	199	57	5	2054_UP
Drug	Coralyne chloride hydrate [38989-38-7]; Up 200; 9.6uM; PC3; HT_HG-U133A	RALGAPA1 VPS13D SPTB CTRC ETV1	1.40e-04	199	57	5	6317_UP
Drug	Morantel tartrate [26155-31-7]; Up 200; 10.8uM; PC3; HT_HG-U133A	SPTB SLC35A2 CTRC AKAP13 ARMC9	1.40e-04	199	57	5	7250_UP
Drug	SR-95639A [115767-94-7]; Down 200; 10uM; PC3; HT_HG-U133A	RALGAPA1 AKAP13 CAMTA2 ABCD1 IL23A	1.40e-04	199	57	5	6632_DN
Drug	Diclofenac sodium [15307-79-6]; Down 200; 12.6uM; MCF7; HT_HG-U133A	RALGAPA1 NBEAL2 PLEC XRCC3 ZNF282	1.40e-04	199	57	5	2756_DN
Drug	Norcyclobenzaprine [303-50-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A	FAR2 NBEAL2 AKAP13 PLEC XRCC3	1.40e-04	199	57	5	2830_DN
Drug	zirconium	HSD3B7 SLC35A2 SLC49A4 LGR5	1.73e-04	111	57	4	CID000023995
Drug	methyl 9-octadecenoate	SPTB SYNE2 SREBF1 ABCD1	1.79e-04	112	57	4	CID000008202
Drug	AC1Q6T4Q	BCKDHA ASPSCR1 ABCD1	1.96e-04	45	57	3	CID000000516
Disease	stearoyl sphingomyelin (d18:1/18:0) measurement	SYNE2 CAMTA2	5.09e-05	6	55	2	EFO_0800611
Disease	platelet-to-lymphocyte ratio	FAR2 INSL6 TMC4 PLEC XRCC3 EXOC3L2	5.80e-05	363	55	6	EFO_0008446
Disease	bipolar disorder (implicated_via_orthology)	ETV1 ETV4	7.12e-05	7	55	2	DOID:3312 (implicated_via_orthology)
Disease	triglycerides in large LDL measurement	ABCA1 HPR SYNE2	7.17e-05	43	55	3	EFO_0022319
Disease	Ewings sarcoma	ETV1 ETV4	9.48e-05	8	55	2	C0553580
Disease	Peripheral Nervous System Diseases	ABCA1 GJE1 CPT1C	1.42e-04	54	55	3	C4721453
Disease	Congenital Disorders of Glycosylation	SRD5A3 SLC35A2	1.52e-04	10	55	2	C0282577
Disease	triglycerides in LDL measurement	ABCA1 HPR SYNE2	1.58e-04	56	55	3	EFO_0022320
Disease	calcium measurement	GRAMD1A SYNE2 SREBF1 HFM1 PLEC EXOC3L2 FER1L5	1.60e-04	628	55	7	EFO_0004838
Disease	dystonia (implicated_via_orthology)	KCNU1 GNAL	2.22e-04	12	55	2	DOID:543 (implicated_via_orthology)
Disease	eosinophil count	VANGL2 SREBF1 ZNF398 AKAP13 HFM1 PLEC EXOC3L2 FER1L5 ZNF282 SLC35A5	3.78e-04	1488	55	10	EFO_0004842
Disease	Bone marrow hypocellularity	FANCL EXOC3L2	5.12e-04	18	55	2	C1855710
Disease	metabolic syndrome	SEC16B ABCA1 HPR SNX10	5.33e-04	200	55	4	EFO_0000195
Disease	obesity (implicated_via_orthology)	SEC16B HPR ETV1 ETV4	6.99e-04	215	55	4	DOID:9970 (implicated_via_orthology)
Disease	HDL cholesterol change measurement	ABCA1 SYNE2	9.17e-04	24	55	2	EFO_0007805
Disease	immature platelet count	FAR2 PLEC EXOC3L2	1.03e-03	106	55	3	EFO_0803544
Disease	Pancytopenia	FANCL EXOC3L2	1.08e-03	26	55	2	C0030312
Disease	immature platelet fraction	FAR2 PLEC EXOC3L2	1.27e-03	114	55	3	EFO_0009187
Disease	right ventricular ejection fraction measurement	ABCA1 PLEC	1.44e-03	30	55	2	EFO_0021816
Disease	immature platelet measurement	FAR2 PLEC EXOC3L2	1.44e-03	119	55	3	EFO_0803541
Disease	heart conduction disease (implicated_via_orthology)	KCNU1 SREBF1	1.63e-03	32	55	2	DOID:10273 (implicated_via_orthology)
Disease	myeloid white cell count	GRAMD1A SREBF1 ETV1 ZNF398 HFM1 EXOC3L2 ZNF282	1.71e-03	937	55	7	EFO_0007988
Disease	Papillary Renal Cell Carcinoma	SYNE2 SLC49A4 AKAP13	1.77e-03	128	55	3	C1306837
Disease	Renal Cell Carcinoma	SYNE2 SLC49A4 AKAP13	1.77e-03	128	55	3	C0007134
Disease	Sarcomatoid Renal Cell Carcinoma	SYNE2 SLC49A4 AKAP13	1.77e-03	128	55	3	C1266043
Disease	Chromophobe Renal Cell Carcinoma	SYNE2 SLC49A4 AKAP13	1.77e-03	128	55	3	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	SYNE2 SLC49A4 AKAP13	1.77e-03	128	55	3	C1266044

Protein segments in the cluster

Peptide	Gene	Start	Entry
LLILLLGSWALFFRR	VANGL2	156	Q9ULK5
LQRLFRRLESQASWL	EXOC3L2	266	Q2M3D2
VQRLSLLLHLAVFLW	FAM74A1	86	Q5RGS3
RSVLDLSLQWRFANL	ASPSCR1	56	Q9BZE9
VFLAALNALLQWLLR	HSD3B7	296	Q9H2F3
LLFLSINLLLAQRWG	ALG3	181	Q92685
QLRLLLWKNLTFRRR	ABCA1	6	O95477
AVRLGLLRLTWFLLQ	AKAP13	171	Q12802
AAVLLFRWNRQALSI	CAMTA2	771	O94983
SVWALLQRNEFLLLL	DIPK1B	196	Q5VUD6
RCFLLIFRLWQNALL	GRAMD1A	186	Q96CP6
ILIALNVLLFYRLWS	GRAMD1A	621	Q96CP6
QRRGALQLWQFLVAL	ETV4	336	P43268
FLQRLLWLLRLLFPR	ABCD1	71	P33897
NTALFLIAWRLLIAR	FAR2	471	Q96K12
ALRSLRWQLLSIIVL	SLC2A7	276	Q6PXP3
LLSLLLFLLLQHWRQ	LILRB4	271	Q8NHJ6
AVISLLLWGRQLFAL	HPR	6	P00739
RLKAFLLQALRWRLT	ARMC9	331	Q7Z3E5
RRGSLQLWQFLVALL	ETV1	331	P50549
NWLGLRFLRALRLLE	KCNU1	191	A8MYU2
NRWLRTISIILFLNK	GNAL	266	P38405
WRDNSLVQLVRLFLI	HFM1	396	A2PYH4
LVLVFLWLHSLRRLF	SRD5A3	131	Q9H8P0
RLQASLLQWYLRLKS	CPT1C	211	Q8TCG5
KRWNALLLRNDIALI	CTRC	111	Q99895
VLLILGFFLNNRSWR	CALHM5	61	Q8N5C1
RWLVLLLFSLLAFVQ	SLC49A4	51	Q96SL1
LSNRILWIGIANFLL	ATG9A	286	Q7Z3C6
WQRLLLRFKILRSLQ	IL23A	156	Q9NPF7
LLRISLAAIAFWLQI	GJE1	121	A6NN92
KRIFWRQILLTLGLL	A3GALT2	11	U3KPV4
SVVFNLLRLLTWELR	IFNL4	156	K9M1U5
LLSLLLILKAGRRWN	EMC6	61	Q9BV81
LRTNFIERFWRNILL	CARD16	156	Q5EG05
QLLSLRSLNLAWNKI	LGR5	396	O75473
WRLNRGLSQAALLLL	BCKDHA	11	P12694
NLSLLRISNWFINAR	TGIF2LY	91	Q8IUE0
LQSRLRQLSLLWEAA	SYNE2	6631	Q8WXH0
LQLKNARLLCSWQLR	FANCL	46	Q9NW38
SLDRKRWQLRSLLLQ	FER1L5	646	A0AVI2
LLIEQFSWRGALLIL	SLC16A12	196	Q6ZSM3
RLSLLWLGLLLVRFS	INSL6	6	Q9Y581
LASLTQQALWLLRLL	NBEAL2	1516	Q6ZNJ1
QQALWLLRLLQDFLC	NBEAL2	1521	Q6ZNJ1
RLLNLELLRQLWVGQ	MIIP	11	Q5JXC2
NRSLSRLQWASLLLL	SLC35A2	161	P78381
SLLWNLIRHLLQRLW	SREBF1	626	P36956
RSILWLNQFLLDLKQ	UHRF1BP1L	536	A0JNW5
REGVRLFLLWLQALQ	RALGAPA1	126	Q6GYQ0
LLFRIVLKRRLNWIQ	SLC35A5	136	Q9BS91
LRLASLVVLLFSLWN	TMC4	436	Q7Z404
LENLLRNRNFWILRL	ZNF398	116	Q8TD17
ILRLWSYLQELLQSR	SPTB	506	P11277
WLLLLLLLQEGSQRR	SLAMF9	6	Q96A28
LRWQEYRELVLLLLQ	PLEC	416	Q15149
RDSALLWQLLVLLCR	SEC16B	361	Q96JE7
EFVWLRQRLQSNALL	SNX10	56	Q9Y5X0
ITWANQLLVRLLADR	XRCC3	286	O43542
LENLLRNRNFWVLRL	ZNF282	171	Q9UDV7
VENLLRNRNFWILRL	ZNF783	116	Q6ZMS7
RWLLRLQLALFVNSL	TMPPE	41	Q6ZT21
NNLRVFLIFDWLLLV	VPS13D	2396	Q5THJ4