Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionP-type sodium transporter activity

ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.63e-0810614GO:0008554
GeneOntologyMolecularFunctionP-type sodium:potassium-exchanging transporter activity

ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.63e-0810614GO:0005391
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC9A9 SLC25A21 SLC9A2 ATP7B SLC41A3 SLC17A1 SLC37A2 ATP1A1 ATP1A2 ATP1A3 ATP1A4 SLC47A2

1.81e-084776112GO:0022804
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC9A9 SLC9A2 ATP7B SLC41A3 SLC17A1 ATP1A1 ATP1A2 ATP1A3 ATP1A4 SLC47A2

2.39e-083016110GO:0022853
GeneOntologyMolecularFunctionP-type potassium transmembrane transporter activity

ATP1A1 ATP1A2 ATP1A3 ATP1A4

2.56e-0811614GO:0008556
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC9A9 SLC9A2 SLC41A3 SLC17A1 ATP1A1 ATP1A2 ATP1A3 ATP1A4

4.91e-08171618GO:0015081
GeneOntologyMolecularFunctionP-type transmembrane transporter activity

ATP7B ATP1A1 ATP1A2 ATP1A3 ATP1A4

7.89e-0836615GO:0140358
GeneOntologyMolecularFunctionP-type ion transporter activity

ATP7B ATP1A1 ATP1A2 ATP1A3 ATP1A4

7.89e-0836615GO:0015662
GeneOntologyMolecularFunctionantigen binding

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20 IGHV3-30-5 HLA-DRA IGHV3-30-3 IGHV3-43D

1.11e-07190618GO:0003823
GeneOntologyMolecularFunctionsteroid hormone binding

ATP1A1 ATP1A2 ATP1A3

9.41e-077613GO:1990239
GeneOntologyMolecularFunctionATPase-coupled monoatomic cation transmembrane transporter activity

ATP7B ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.27e-0662615GO:0019829
GeneOntologyMolecularFunctionantiporter activity

SLC9A9 SLC25A21 SLC9A2 SLC41A3 SLC37A2 SLC47A2

3.97e-06138616GO:0015297
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC9A9 SLC9A2 ATP7B SLC41A3 SLC17A1 ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.10e-05465619GO:0046873
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

SLC9A9 SLC9A2 ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.19e-05167616GO:0015079
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC9A9 SLC9A2 ATP7B SLC41A3 SLC17A1 SLC37A2 ATP1A1 ATP1A2 ATP1A3 ATP1A4 SLC47A2

1.62e-057586111GO:0015318
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC9A9 SLC9A2 ATP7B SLC41A3 SLC17A1 ATP1A1 ATP1A2 ATP1A3 ATP1A4 SLC47A2

1.85e-056276110GO:0022890
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ATP7B ATP1A1 ATP1A2 ATP1A3 ATP1A4

2.06e-05109615GO:0042626
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC9A9 SLC9A2 ATP7B SLC41A3 SLC17A1 ATP1A1 ATP1A2 ATP1A3 ATP1A4 SLC47A2

3.01e-056646110GO:0008324
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC9A9 SLC25A21 SLC9A2 SLC41A3 SLC17A1 SLC37A2 SLC47A2

3.22e-05296617GO:0015291
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC9A9 SLC25A21 SLC9A2 ATP7B SLC41A3 SLC17A1 SLC37A2 ATP1A1 ATP1A2 ATP1A3 ATP1A4 SLC7A10 SLC47A2

4.62e-0511806113GO:0022857
GeneOntologyMolecularFunctiontransporter activity

SLC9A9 SLC25A21 SLC9A2 ATP7B SLC41A3 SLC17A1 SLC37A2 ATP1A1 ATP1A2 ATP1A3 ATP1A4 SLC7A10 SLC47A2

1.14e-0412896113GO:0005215
GeneOntologyMolecularFunctionprotein-folding chaperone binding

GPR37 ATP1A1 ATP1A2 ATP1A3 TG

1.32e-04161615GO:0051087
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC9A9 SLC9A2 ATP7B SLC41A3 SLC17A1 ATP1A1 ATP1A2 ATP1A3 ATP1A4 SLC47A2

1.33e-047936110GO:0015075
GeneOntologyMolecularFunctionacetyl-CoA C-acetyltransferase activity

ACAA2 HADHB

1.37e-046612GO:0003985
GeneOntologyMolecularFunctionC-acetyltransferase activity

ACAA2 HADHB

1.91e-047612GO:0016453
GeneOntologyMolecularFunctionacetyl-CoA C-acyltransferase activity

ACAA2 HADHB

1.91e-047612GO:0003988
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

ATP7B ATP1A1 ATP1A2 ATP1A3 ATP1A4

2.11e-04178615GO:0015399
GeneOntologyMolecularFunction3-keto sterol reductase activity

DHRS4 DHRS4L2

2.54e-048612GO:0000253
GeneOntologyMolecularFunctionmetal cation:monoatomic cation antiporter activity

SLC9A9 SLC9A2 SLC41A3

3.07e-0443613GO:0140828
GeneOntologyMolecularFunctioncarbonyl reductase (NADPH) activity

DHRS4 DHRS4L2

3.26e-049612GO:0004090
GeneOntologyMolecularFunctionATP hydrolysis activity

BRIP1 ATP7B ATP1A1 ATP1A2 ATP1A3 ATP1A4 FANCM

3.81e-04441617GO:0016887
GeneOntologyMolecularFunctionATP-dependent activity

BRIP1 ATP7B MOCS3 ATP1A1 ATP1A2 ATP1A3 ATP1A4 FANCM

5.35e-04614618GO:0140657
GeneOntologyMolecularFunctionneuropeptide receptor activity

GPR37 NMUR1 GPR151

5.70e-0453613GO:0008188
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

HSD3B7 DHRS4 DHRS4L2 HADHB

6.15e-04127614GO:0016616
GeneOntologyMolecularFunctionretinal dehydrogenase activity

DHRS4 DHRS4L2

8.16e-0414612GO:0001758
GeneOntologyMolecularFunctionpotassium ion binding

ATP1A1 ATP1A2

8.16e-0414612GO:0030955
GeneOntologyMolecularFunctionpotassium:proton antiporter activity

SLC9A9 SLC9A2

8.16e-0414612GO:0015386
GeneOntologyMolecularFunctionsodium ion binding

ATP1A1 ATP1A2

8.16e-0414612GO:0031402
GeneOntologyMolecularFunctionoxidoreductase activity, acting on CH-OH group of donors

HSD3B7 DHRS4 DHRS4L2 HADHB

8.40e-04138614GO:0016614
GeneOntologyMolecularFunctionall-trans-retinol dehydrogenase (NADP+) activity

DHRS4 DHRS4L2

9.40e-0415612GO:0052650
GeneOntologyMolecularFunctionsodium:proton antiporter activity

SLC9A9 SLC9A2

1.07e-0316612GO:0015385
GeneOntologyMolecularFunctionsolute:potassium antiporter activity

SLC9A9 SLC9A2

1.52e-0319612GO:0022821
GeneOntologyMolecularFunctionC-acyltransferase activity

ACAA2 HADHB

1.86e-0321612GO:0016408
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

EEF2 BRIP1 ATP7B ATP1A1 ATP1A2 ATP1A3 ATP1A4 FANCM

2.37e-03775618GO:0017111
GeneOntologyMolecularFunctionphosphate transmembrane transporter activity

SLC17A1 SLC37A2

2.43e-0324612GO:0005315
GeneOntologyMolecularFunctionalkali metal ion binding

ATP1A1 ATP1A2

2.85e-0326612GO:0031420
GeneOntologyMolecularFunctionalcohol dehydrogenase (NADP+) activity

DHRS4 DHRS4L2

3.07e-0327612GO:0008106
GeneOntologyMolecularFunctionfatty acyl-CoA hydrolase activity

BAAT ACAA2

3.07e-0327612GO:0047617
GeneOntologyMolecularFunctionmetal cation:proton antiporter activity

SLC9A9 SLC9A2

3.07e-0327612GO:0051139
GeneOntologyMolecularFunctionacyl-CoA hydrolase activity

BAAT ACAA2

3.30e-0328612GO:0016289
GeneOntologyMolecularFunctionalcohol dehydrogenase [NAD(P)+] activity

DHRS4 DHRS4L2

3.78e-0330612GO:0018455
GeneOntologyMolecularFunctionpyrophosphatase activity

EEF2 BRIP1 ATP7B ATP1A1 ATP1A2 ATP1A3 ATP1A4 FANCM

3.85e-03839618GO:0016462
GeneOntologyMolecularFunctionhormone binding

ATP1A1 ATP1A2 ATP1A3

3.86e-03103613GO:0042562
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

EEF2 BRIP1 ATP7B ATP1A1 ATP1A2 ATP1A3 ATP1A4 FANCM

3.88e-03840618GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

EEF2 BRIP1 ATP7B ATP1A1 ATP1A2 ATP1A3 ATP1A4 FANCM

3.88e-03840618GO:0016818
GeneOntologyMolecularFunctionacetyltransferase activity

NCOA1 ACAA2 HADHB

3.97e-03104613GO:0016407
GeneOntologyMolecularFunctionaldo-keto reductase (NADPH) activity

DHRS4 DHRS4L2

4.29e-0332612GO:0004033
GeneOntologyMolecularFunctionneuropeptide binding

GPR37 NMUR1

5.71e-0337612GO:0042923
GeneOntologyMolecularFunctionacyltransferase activity, transferring groups other than amino-acyl groups

BAAT NCOA1 ACAA2 HADHB

6.04e-03238614GO:0016747
GeneOntologyMolecularFunctionG protein-coupled peptide receptor activity

GPR37 NMUR1 GPR151

7.85e-03133613GO:0008528
GeneOntologyMolecularFunctionsteroid binding

ATP1A1 ATP1A2 ATP1A3

7.85e-03133613GO:0005496
GeneOntologyMolecularFunctionpeptide receptor activity

GPR37 NMUR1 GPR151

9.03e-03140613GO:0001653
GeneOntologyMolecularFunctionthiolester hydrolase activity

BAAT ACAA2

9.08e-0347612GO:0016790
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

DHRS4 DHRS4L2

9.46e-0348612GO:0016620
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the aldehyde or oxo group of donors

DHRS4 DHRS4L2

1.27e-0256612GO:0016903
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor

DHRS4 DHRS4L2

1.45e-0260612GO:0016655
GeneOntologyMolecularFunctionDNA helicase activity

BRIP1 FANCM

1.54e-0262612GO:0003678
GeneOntologyBiologicalProcessestablishment or maintenance of transmembrane electrochemical gradient

ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.96e-0811594GO:0010248
GeneOntologyBiologicalProcessimmunoglobulin mediated immune response

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20 IGHV3-30-5 HLA-DRA IGHV3-30-3 C5 IGHV3-43D

2.13e-08235599GO:0016064
GeneOntologyBiologicalProcessB cell mediated immunity

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20 IGHV3-30-5 HLA-DRA IGHV3-30-3 C5 IGHV3-43D

2.94e-08244599GO:0019724
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SLC9A9 SLC9A2 SLC41A3 SLC17A1 ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.33e-07208598GO:0035725
GeneOntologyBiologicalProcessintracellular potassium ion homeostasis

ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.40e-0717594GO:0030007
GeneOntologyBiologicalProcesssodium ion export across plasma membrane

ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.40e-0717594GO:0036376
GeneOntologyBiologicalProcessresponse to glycoside

ATP1A1 ATP1A2 ATP1A3

2.21e-075593GO:1903416
GeneOntologyBiologicalProcessexport across plasma membrane

ATP7B ATP1A1 ATP1A2 ATP1A3 ATP1A4 SLC47A2

2.33e-0791596GO:0140115
GeneOntologyBiologicalProcessproton transmembrane transport

SLC9A9 SLC9A2 ATP1A1 ATP1A2 ATP1A3 ATP1A4 SLC47A2

5.43e-07170597GO:1902600
GeneOntologyBiologicalProcesssodium ion transport

SLC9A9 SLC9A2 SLC41A3 SLC17A1 ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.11e-06275598GO:0006814
GeneOntologyBiologicalProcessintracellular sodium ion homeostasis

ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.57e-0630594GO:0006883
GeneOntologyBiologicalProcessinorganic ion import across plasma membrane

SLC9A9 SLC9A2 ATP1A1 ATP1A2 ATP1A3 ATP1A4

3.20e-06142596GO:0099587
GeneOntologyBiologicalProcessinorganic cation import across plasma membrane

SLC9A9 SLC9A2 ATP1A1 ATP1A2 ATP1A3 ATP1A4

3.20e-06142596GO:0098659
GeneOntologyBiologicalProcesspotassium ion homeostasis

ATP1A1 ATP1A2 ATP1A3 ATP1A4

3.72e-0637594GO:0055075
GeneOntologyBiologicalProcesslymphocyte mediated immunity

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20 IGHV3-30-5 HLA-DRA IGHV3-30-3 C5 IGHV3-43D

4.85e-06449599GO:0002449
GeneOntologyBiologicalProcessadaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20 IGHV3-30-5 HLA-DRA IGHV3-30-3 C5 IGHV3-43D

6.11e-06462599GO:0002460
GeneOntologyBiologicalProcesspotassium ion import across plasma membrane

ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.36e-0551594GO:1990573
GeneOntologyBiologicalProcesssodium ion homeostasis

ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.36e-0551594GO:0055078
GeneOntologyBiologicalProcessleukocyte mediated immunity

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20 IGHV3-30-5 HLA-DRA IGHV3-30-3 C5 IGHV3-43D

3.51e-05576599GO:0002443
GeneOntologyBiologicalProcessimport across plasma membrane

SLC9A9 SLC9A2 ATP1A1 ATP1A2 ATP1A3 ATP1A4

4.95e-05230596GO:0098739
GeneOntologyBiologicalProcesspotassium ion transmembrane transport

SLC9A9 SLC9A2 ATP1A1 ATP1A2 ATP1A3 ATP1A4

5.20e-05232596GO:0071805
GeneOntologyBiologicalProcesscell communication by electrical coupling involved in cardiac conduction

ATP1A1 ATP1A2 ATP1A3

5.52e-0526593GO:0086064
GeneOntologyBiologicalProcesspotassium ion transport

SLC9A9 SLC9A2 ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.25e-04272596GO:0006813
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SLC9A9 SLC9A2 ATP7B SLC41A3 SLC17A1 SLC37A2 ATP1A1 ATP1A2 ATP1A3 ATP1A4 SLC47A2

1.26e-0410175911GO:0098660
GeneOntologyBiologicalProcesscell communication by electrical coupling

ATP1A1 ATP1A2 ATP1A3

1.36e-0435593GO:0010644
GeneOntologyBiologicalProcessmonoatomic cation homeostasis

CA12 SLC9A9 SLC9A2 ATP7B PKHD1 ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.65e-04705599GO:0055080
GeneOntologyBiologicalProcessmonoatomic ion homeostasis

CA12 SLC9A9 SLC9A2 ATP7B PKHD1 ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.87e-04717599GO:0050801
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

SLC9A9 SLC9A2 ATP7B SLC41A3 SLC17A1 ATP1A1 ATP1A2 ATP1A3 ATP1A4 SLC47A2

2.60e-049225910GO:0098662
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SLC9A9 SLC9A2 ATP7B SLC41A3 SLC17A1 ATP1A1 ATP1A2 ATP1A3 ATP1A4 SLC47A2

3.08e-049425910GO:0098655
GeneOntologyBiologicalProcessintracellular monoatomic cation homeostasis

SLC9A9 SLC9A2 ATP7B PKHD1 ATP1A1 ATP1A2 ATP1A3 ATP1A4

3.32e-04611598GO:0030003
GeneOntologyBiologicalProcessintracellular monoatomic ion homeostasis

SLC9A9 SLC9A2 ATP7B PKHD1 ATP1A1 ATP1A2 ATP1A3 ATP1A4

3.74e-04622598GO:0006873
GeneOntologyBiologicalProcessregulation of pH

CA12 SLC9A9 SLC9A2 ATP1A4

3.87e-04120594GO:0006885
GeneOntologyBiologicalProcessmonoatomic ion transport

SLC9A9 SLC9A2 ATP7B SLC41A3 SLC17A1 NMUR1 ATP1A1 ATP1A2 ATP1A3 ATP1A4 SLC47A2 TG

4.36e-0413745912GO:0006811
GeneOntologyBiologicalProcessadaptive immune response

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20 IGHV3-30-5 HLA-DRA IGHV3-30-3 C5 IGHV3-43D

5.86e-04838599GO:0002250
GeneOntologyBiologicalProcesscell communication involved in cardiac conduction

ATP1A1 ATP1A2 ATP1A3

6.45e-0459593GO:0086065
GeneOntologyBiologicalProcessimmune effector process

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20 IGHV3-30-5 HLA-DRA IGHV3-30-3 C5 IGHV3-43D

6.99e-04859599GO:0002252
GeneOntologyBiologicalProcesschemical homeostasis

CA12 CCN4 SLC9A9 SLC9A2 ATP7B ASGR2 PKHD1 ATP1A1 ATP1A2 ATP1A3 ATP1A4

7.31e-0412495911GO:0048878
GeneOntologyBiologicalProcessphosphate ion transmembrane transport

SLC17A1 SLC37A2

8.25e-0415592GO:0035435
GeneOntologyBiologicalProcessL-ascorbic acid metabolic process

ATP1A2 ATP1A3

9.41e-0416592GO:0019852
GeneOntologyBiologicalProcessorganic acid catabolic process

SDSL SLC25A21 LPIN2 ACAA2 HADHB

1.08e-03272595GO:0016054
GeneOntologyBiologicalProcesscarboxylic acid catabolic process

SDSL SLC25A21 LPIN2 ACAA2 HADHB

1.08e-03272595GO:0046395
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SLC9A9 SLC9A2 ATP7B SLC41A3 SLC17A1 ATP1A1 ATP1A2 ATP1A3 ATP1A4 SLC47A2

1.14e-0311155910GO:0034220
GeneOntologyBiologicalProcesssmall molecule catabolic process

SDSL HSD3B7 SLC25A21 LPIN2 ACAA2 HADHB

1.26e-03421596GO:0044282
GeneOntologyBiologicalProcesslactone metabolic process

ATP1A2 ATP1A3

1.33e-0319592GO:1901334
GeneOntologyBiologicalProcessestrous cycle

CA12 NCOA1

1.48e-0320592GO:0044849
GeneOntologyBiologicalProcessmonoatomic cation transport

SLC9A9 SLC9A2 ATP7B SLC41A3 SLC17A1 ATP1A1 ATP1A2 ATP1A3 ATP1A4 SLC47A2

1.51e-0311575910GO:0006812
GeneOntologyBiologicalProcessrelaxation of cardiac muscle

ATP1A1 ATP1A2

1.63e-0321592GO:0055119
GeneOntologyBiologicalProcessresponse to potassium ion

ATP1A2 ATP1A3

1.63e-0321592GO:0035864
GeneOntologyBiologicalProcessretinal metabolic process

DHRS4 DHRS4L2

1.63e-0321592GO:0042574
GeneOntologyBiologicalProcessinorganic anion transport

SLC17A1 SLC37A2 NMUR1 TG

1.76e-03180594GO:0015698
GeneOntologyCellularComponentsodium:potassium-exchanging ATPase complex

ATP1A1 ATP1A2 ATP1A3 ATP1A4

3.19e-0812614GO:0005890
GeneOntologyCellularComponentimmunoglobulin complex

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20 IGHV3-30-5 IGHV3-30-3 IGHV3-43D

5.34e-07166617GO:0019814
GeneOntologyCellularComponentcation-transporting ATPase complex

ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.26e-0549614GO:0090533
GeneOntologyCellularComponentATPase dependent transmembrane transport complex

ATP1A1 ATP1A2 ATP1A3 ATP1A4

2.00e-0555614GO:0098533
GeneOntologyCellularComponentphotoreceptor inner segment membrane

ATP1A1 ATP1A3

5.01e-054612GO:0060342
HumanPhenoEpisodic quadriplegia

ATP1A2 ATP1A3

1.78e-052222HP:0200072
DomainP-type_ATPase_IIC

ATP1A1 ATP1A2 ATP1A3 ATP1A4

7.37e-106514IPR005775
Domain-

ATP7B ATP1A1 ATP1A2 ATP1A3 ATP1A4

2.36e-08325153.40.1110.10
Domain-

ATP7B ATP1A1 ATP1A2 ATP1A3 ATP1A4

2.36e-08325152.70.150.10
DomainATPase_P-typ_cyto_domN

ATP7B ATP1A1 ATP1A2 ATP1A3 ATP1A4

3.79e-0835515IPR023299
DomainP_typ_ATPase

ATP7B ATP1A1 ATP1A2 ATP1A3 ATP1A4

4.39e-0836515IPR001757
DomainATPase_P-typ_P_site

ATP7B ATP1A1 ATP1A2 ATP1A3 ATP1A4

4.39e-0836515IPR018303
DomainATPASE_E1_E2

ATP7B ATP1A1 ATP1A2 ATP1A3 ATP1A4

4.39e-0836515PS00154
DomainATPase_P-typ_transduc_dom_A

ATP7B ATP1A1 ATP1A2 ATP1A3 ATP1A4

5.07e-0837515IPR008250
DomainE1-E2_ATPase

ATP7B ATP1A1 ATP1A2 ATP1A3 ATP1A4

5.07e-0837515PF00122
DomainHAD-like_dom

ATP7B LPIN2 ATP1A1 ATP1A2 ATP1A3 ATP1A4

7.31e-0879516IPR023214
Domain-

ATP1A1 ATP1A2 ATP1A3 ATP1A4

8.76e-08165141.20.1110.10
DomainATPase_P-typ_TM_dom

ATP1A1 ATP1A2 ATP1A3 ATP1A4

8.76e-0816514IPR023298
DomainATPase_P-typ_cation-transptr_C

ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.14e-0717514IPR006068
DomainCation_ATPase_C

ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.14e-0717514PF00689
DomainCation_ATPase_N

ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.47e-0718514PF00690
DomainCation_ATPase_N

ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.47e-0718514SM00831
DomainATPase_P-typ_cation-transptr_N

ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.85e-0719514IPR004014
DomainThiolase_AS

ACAA2 HADHB

7.27e-055512IPR020610
DomainThiolase_acyl_enz_int_AS

ACAA2 HADHB

7.27e-055512IPR020615
DomainThiolase_C

ACAA2 HADHB

1.09e-046512PF02803
DomainThiolase_N

ACAA2 HADHB

1.09e-046512PF00108
DomainTHIOLASE_2

ACAA2 HADHB

1.09e-046512PS00737
DomainTHIOLASE_1

ACAA2 HADHB

1.09e-046512PS00098
DomainTHIOLASE_3

ACAA2 HADHB

1.09e-046512PS00099
DomainThiolase_N

ACAA2 HADHB

1.09e-046512IPR020616
DomainThiolase_C

ACAA2 HADHB

1.09e-046512IPR020617
DomainThiolase_CS

ACAA2 HADHB

1.09e-046512IPR020613
DomainThiolase

ACAA2 HADHB

1.09e-046512IPR002155
DomainNaH_exchanger

SLC9A9 SLC9A2

2.60e-049512IPR004709
Domain-

ACAA2 HADHB

3.24e-04105123.40.47.10
DomainThiolase-like

ACAA2 HADHB

3.24e-0410512IPR016039
DomainCation/H_exchanger_CPA1

SLC9A9 SLC9A2

3.96e-0411512IPR018422
DomainNa_H_Exchanger

SLC9A9 SLC9A2

6.51e-0414512PF00999
DomainCation/H_exchanger

SLC9A9 SLC9A2

6.51e-0414512IPR006153
DomainIPT

MST1R PKHD1

2.46e-0327512SM00429
DomainTIG

MST1R PKHD1

3.23e-0331512PF01833
DomainIPT

MST1R PKHD1

3.44e-0332512IPR002909
DomainDNA/RNA_helicase_DEAH_CS

BRIP1 FANCM

4.11e-0335512IPR002464
DomainDEAH_ATP_HELICASE

BRIP1 FANCM

4.83e-0338512PS00690
PathwayKEGG_PROXIMAL_TUBULE_BICARBONATE_RECLAMATION

ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.28e-0623514M4361
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

ATP7B ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.54e-0655515M971
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

ATP7B ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.84e-0657515MM15643
PathwayREACTOME_CD22_MEDIATED_BCR_REGULATION

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

7.32e-0635514MM17219
PathwayREACTOME_CLASSICAL_ANTIBODY_MEDIATED_COMPLEMENT_ACTIVATION

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

1.14e-0539514MM17212
PathwayREACTOME_COMPLEMENT_CASCADE

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20 C5

1.26e-0584515MM14653
PathwayKEGG_ALDOSTERONE_REGULATED_SODIUM_REABSORPTION

ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.54e-0542514M16473
PathwayREACTOME_POTENTIAL_THERAPEUTICS_FOR_SARS

IGHV3-33 IGHV3-30 ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.85e-05154516M39007
PathwayREACTOME_ROLE_OF_LAT2_NTAL_LAB_ON_CALCIUM_MOBILIZATION

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

2.03e-0545514MM14912
PathwayREACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20 JAML SLC7A10

2.14e-05158516MM14812
PathwayREACTOME_FCGR_ACTIVATION

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

2.63e-0548514MM17214
PathwayREACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_BCR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

3.90e-0553514MM15716
PathwayREACTOME_ION_HOMEOSTASIS

ATP1A1 ATP1A2 ATP1A3 ATP1A4

4.20e-0554514M27460
PathwayREACTOME_ION_HOMEOSTASIS

ATP1A1 ATP1A2 ATP1A3 ATP1A4

4.20e-0554514MM15202
PathwayREACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

4.20e-0554514MM14655
PathwayREACTOME_ROLE_OF_PHOSPHOLIPIDS_IN_PHAGOCYTOSIS

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

4.86e-0556514MM14815
PathwayREACTOME_FCERI_MEDIATED_CA_2_MOBILIZATION

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

5.58e-0558514MM14914
PathwayREACTOME_FCERI_MEDIATED_MAPK_ACTIVATION

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

6.38e-0560514MM14913
PathwayREACTOME_BINDING_AND_UPTAKE_OF_LIGANDS_BY_SCAVENGER_RECEPTORS

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

6.38e-0560514MM14872
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL

HSD3B7 BAAT NCOA1

7.51e-0523513M1926
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL

HSD3B7 BAAT NCOA1

7.51e-0523513MM14741
PathwayREACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20 JAML

1.23e-04135515MM14781
PathwayKEGG_CARDIAC_MUSCLE_CONTRACTION

ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.87e-0479514M17673
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS

HSD3B7 BAAT NCOA1

2.25e-0433513M5967
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS

HSD3B7 BAAT NCOA1

2.25e-0433513MM14737
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC9A9 SLC9A2 ATP7B SLC17A1 ATP1A1 ATP1A2 ATP1A3 ATP1A4 SLC7A10 SLC47A2

2.58e-047365110M27287
PathwayREACTOME_ION_CHANNEL_TRANSPORT

ATP7B ATP1A1 ATP1A2 ATP1A3 ATP1A4

4.23e-04176515MM15718
PathwayREACTOME_SODIUM_PROTON_EXCHANGERS

SLC9A9 SLC9A2

4.55e-049512M27337
PathwayREACTOME_SODIUM_PROTON_EXCHANGERS

SLC9A9 SLC9A2

4.55e-049512MM15079
PathwayREACTOME_ION_CHANNEL_TRANSPORT

ATP7B ATP1A1 ATP1A2 ATP1A3 ATP1A4

5.05e-04183515M997
PathwayREACTOME_CARDIAC_CONDUCTION

ATP1A1 ATP1A2 ATP1A3 ATP1A4

5.16e-04103514MM15196
PathwayREACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM

HSD3B7 BAAT NCOA1

5.32e-0444513M499
PathwayKEGG_MEDICUS_REFERENCE_ISOLEUCINE_DEGRADATION

ACAA2 HADHB

5.67e-0410512M47635
PathwayREACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM

HSD3B7 BAAT NCOA1

5.69e-0445513MM14751
PathwayREACTOME_FCERI_MEDIATED_NF_KB_ACTIVATION

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

5.96e-04107514MM14915
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC9A9 SLC9A2 SLC17A1 SLC7A10

6.17e-04108514M823
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC9A9 SLC9A2 SLC17A1 SLC7A10

6.39e-04109514MM15074
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC9A9 SLC9A2 ATP7B SLC17A1 ATP1A1 ATP1A2 ATP1A3 ATP1A4 SLC7A10

6.67e-04681519MM14985
PathwayKEGG_MEDICUS_REFERENCE_BETA_OXIDATION

ACAA2 HADHB

6.91e-0411512M47630
PathwayREACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

7.56e-04114514MM14814
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_27_HYDROXYCHOLESTEROL

HSD3B7 NCOA1

1.14e-0314512M27074
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_27_HYDROXYCHOLESTEROL

HSD3B7 NCOA1

1.14e-0314512MM14748
PathwayREACTOME_CARDIAC_CONDUCTION

ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.23e-03130514M27454
PathwayREACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

1.27e-03131514MM15717
PathwayREACTOME_SARS_COV_INFECTIONS

IGHV3-33 IGHV3-30 NUP210 ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.44e-03471517M39009
PathwayKEGG_PRIMARY_BILE_ACID_BIOSYNTHESIS

HSD3B7 BAAT

1.49e-0316512M3214
PathwayREACTOME_PEROXISOMAL_PROTEIN_IMPORT

DHRS4 DHRS4L2 BAAT

1.66e-0365513MM15628
PathwayREACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS

BAAT NCOA1

1.89e-0318512M4862
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC9A9 SLC9A2 SLC17A1 SLC7A10 SLC47A2

2.00e-03249515M5988
PathwayREACTOME_FC_EPSILON_RECEPTOR_FCERI_SIGNALING

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

2.09e-03150514MM14889
PathwayREACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS

BAAT NCOA1

2.11e-0319512MM14612
PathwayREACTOME_MUSCLE_CONTRACTION

ATP1A1 ATP1A2 ATP1A3 ATP1A4

2.95e-03165514MM15026
Pubmed

Preactivation of AMPK by metformin may ameliorate the epithelial cell damage caused by renal ischemia.

ATP1A1 ATP1A2 ATP1A3 ATP1A4

8.56e-12461421849490
Pubmed

Multiple genes encode the human Na+,K+-ATPase catalytic subunit.

ATP1A1 ATP1A2 ATP1A3 ATP1A4

4.28e-1156143035563
Pubmed

The family of human Na+,K+-ATPase genes. No less than five genes and/or pseudogenes related to the alpha-subunit.

ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.28e-1066143036582
Pubmed

Differential involvement of Na(+),K(+)-ATPase isozymes in preimplantation development of the mouse.

ATP1A1 ATP1A2 ATP1A3 ATP1A4

2.98e-10761410837135
Pubmed

Molecular genetics of Na,K-ATPase.

ATP1A1 ATP1A2 ATP1A3 ATP1A4

2.98e-1076142158121
Pubmed

Biology, structure and mechanism of P-type ATPases.

ATP7B ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.61e-092961515071553
Pubmed

Three differentially expressed Na,K-ATPase alpha subunit isoforms: structural and functional implications.

ATP1A1 ATP1A2 ATP1A3

5.13e-0936132822726
Pubmed

Na+/K+-ATPase α isoform deficiency results in distinct spreading depolarization phenotypes.

ATP1A1 ATP1A2 ATP1A3

5.13e-09361330819023
Pubmed

Identification of a VxP Targeting Signal in the Flagellar Na+ /K+ -ATPase.

ATP1A1 ATP1A3 ATP1A4

5.13e-09361326373354
Pubmed

Differential expression of Na+/K+-ATPase alpha-subunits in mouse hippocampal interneurones and pyramidal cells.

ATP1A1 ATP1A2 ATP1A3

5.13e-09361317947306
Pubmed

Association between sodium- and potassium-activated adenosine triphosphatase alpha isoforms and bipolar disorders.

ATP1A1 ATP1A2 ATP1A3

5.13e-09361319058785
Pubmed

Knockout of sodium pump α3 subunit gene (Atp1a3-/-) results in perinatal seizure and defective respiratory rhythm generation.

ATP1A1 ATP1A2 ATP1A3

5.13e-09361328465228
Pubmed

Developmental cell-specific regulation of Na(+)-K(+)-ATPase alpha 1-, alpha 2-, and alpha 3-isoform gene expression.

ATP1A1 ATP1A2 ATP1A3

5.13e-0936138203495
Pubmed

Na,K-ATPase and the role of alpha isoforms in behavior.

ATP1A1 ATP1A2 ATP1A3

5.13e-09361318044013
Pubmed

Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model.

ATP1A1 ATP1A2 ATP1A3

5.13e-09361326911348
Pubmed

Cardiac glycosides induced toxicity in human cells expressing α1-, α2-, or α3-isoforms of Na-K-ATPase.

ATP1A1 ATP1A2 ATP1A3

5.13e-09361325994790
Pubmed

1.3 A X-ray structure of an antibody Fv fragment used for induced membrane-protein crystallization.

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

1.15e-081561412657787
Pubmed

Increased susceptibility to cortical spreading depression in the mouse model of familial hemiplegic migraine type 2.

ATP1A1 ATP1A2 ATP1A3

2.05e-08461321731499
Pubmed

The Na,K-ATPase alpha 2 isoform is expressed in neurons, and its absence disrupts neuronal activity in newborn mice.

ATP1A1 ATP1A2 ATP1A3

2.05e-08461312458206
Pubmed

Muscle Na+-K+-ATPase activity and isoform adaptations to intense interval exercise and training in well-trained athletes.

ATP1A1 ATP1A2 ATP1A3

2.05e-08461317446412
Pubmed

Isoform specificity of cardiac glycosides binding to human Na+,K+-ATPase alpha1beta1, alpha2beta1 and alpha3beta1.

ATP1A1 ATP1A2 ATP1A3

2.05e-08461319751721
Pubmed

Agrin regulation of alpha3 sodium-potassium ATPase activity modulates cardiac myocyte contraction.

ATP1A1 ATP1A2 ATP1A3

2.05e-08461319376779
Pubmed

Deficiency in Na,K-ATPase alpha isoform genes alters spatial learning, motor activity, and anxiety in mice.

ATP1A1 ATP1A2 ATP1A3

2.05e-08461317234593
Pubmed

Family of Na+,K+-ATPase genes. Intra-individual tissue-specific restriction fragment length polymorphism.

ATP1A1 ATP1A3 ATP1A4

2.05e-0846132887455
Pubmed

Ouabain inhibits tubuloglomerular feedback in mutant mice with ouabain-sensitive alpha1 Na,K-ATPase.

SLC9A2 ATP1A1 ATP1A2

5.12e-08561316870707
Pubmed

Early onset of somatic mutation in immunoglobulin VH genes during the primary immune response.

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

6.12e-08226142499654
Pubmed

Transport and pharmacological properties of nine different human Na, K-ATPase isozymes.

ATP1A1 ATP1A2 ATP1A3

1.02e-07661310636900
Pubmed

Expression and distribution of Na, K-ATPase isoforms in the human uterus.

ATP1A1 ATP1A2 ATP1A3

1.79e-07761320065300
Pubmed

Dysfunction of ouabain-induced cardiac contractility in mice with heart-specific ablation of Na,K-ATPase beta1-subunit.

ATP1A1 ATP1A2 ATP1A3

2.86e-07861319683723
Pubmed

Genes encoding alpha and beta subunits of Na,K-ATPase are located on three different chromosomes in the mouse.

ATP1A1 ATP1A2 ATP1A3

2.86e-0786132885848
Pubmed

Enhanced inhibitory neurotransmission in the cerebellar cortex of Atp1a3-deficient heterozygous mice.

ATP1A1 ATP1A2 ATP1A3

2.86e-07861323652595
Pubmed

The Na(+)-K(+)-ATPase alpha2-subunit isoform modulates contractility in the perinatal mouse diaphragm.

ATP1A1 ATP1A2 ATP1A3

4.28e-07961315253893
Pubmed

Retinal pigment epithelial integrity is compromised in the developing albino mouse retina.

ATP1A1 ATP1A2 ATP1A3

1.12e-061261327097562
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

EEF2 NUP210 PKHD1 ATP1A1 ATP1A2 ATP1A3

1.52e-0620261624639526
Pubmed

Chromosomal assignments of 17 structural genes and 11 related DNA fragments in rats (Rattus norvegicus) by Southern blot analysis of rat x mouse somatic cell hybrid clones.

ATP1A1 ATP1A2 ATP1A3

1.84e-06146131572638
Pubmed

Decreased expression of both the alpha1- and alpha2-subunits of the Na-K-ATPase reduces maximal alveolar epithelial fluid clearance.

ATP1A1 ATP1A2

3.03e-06261215781423
Pubmed

CDNA cloning of a short isoform of human liver NADP (H) -dependent retinol dehydrogenase/reductase and analysis of its characteristics.

DHRS4 DHRS4L2

3.03e-06261215473316
Pubmed

Immunohistochemical analyses of alpha1 and alpha3 Na+/K+-ATPase subunit expression in medulloblastomas.

ATP1A1 ATP1A3

3.03e-06261221498719
Pubmed

Molecular cloning of the mouse ouabain-resistance gene.

ATP1A1 ATP1A2

3.03e-0626126324196
Pubmed

Marinobufagenin enhances cardiac contractility in mice with ouabain-sensitive alpha1 Na+-K+-ATPase.

ATP1A1 ATP1A2

3.03e-06261219376809
Pubmed

A real-time PCR method to genotype mutant mouse models with altered affinity for cardiotonic steroids on the Na,K-ATPase.

ATP1A1 ATP1A2

3.03e-06261235446892
Pubmed

New molecular determinants controlling the accessibility of ouabain to its binding site in human Na,K-ATPase alpha isoforms.

ATP1A1 ATP1A2

3.03e-06261214742675
Pubmed

ATP1A2- and ATP1A3-associated early profound epileptic encephalopathy and polymicrogyria.

ATP1A2 ATP1A3

3.03e-06261233880529
Pubmed

Alternative transcription initiation and splicing variants of the DHRS4 gene cluster.

DHRS4 DHRS4L2

3.03e-06261218754758
Pubmed

Expression of a novel alternatively spliced variant of NADP(H)-dependent retinol dehydrogenase/reductase with deletion of exon 3 in cervical squamous carcinoma.

DHRS4 DHRS4L2

3.03e-06261217230527
Pubmed

The alpha(1)- and alpha(2)-isoforms of Na-K-ATPase play different roles in skeletal muscle contractility.

ATP1A1 ATP1A2

3.03e-06261211507009
Pubmed

The Na,K-ATPase alpha4 gene (Atp1a4) encodes a ouabain-resistant alpha subunit and is tightly linked to the alpha2 gene (Atp1a2) on mouse chromosome 1.

ATP1A2 ATP1A4

3.03e-06261210555956
Pubmed

The structure of the Na+,K+-ATPase and mapping of isoform differences and disease-related mutations.

ATP1A2 ATP1A3

3.03e-06261218957371
Pubmed

All human Na(+)-K(+)-ATPase alpha-subunit isoforms have a similar affinity for cardiac glycosides.

ATP1A1 ATP1A3

3.03e-06261211546672
Pubmed

Properties and expression of Na+/K+-ATPase α-subunit isoforms in the brain of the swamp eel, Monopterus albus, which has unusually high brain ammonia tolerance.

ATP1A1 ATP1A3

3.03e-06261224391932
Pubmed

DOCA-salt hypertension does not require the ouabain-sensitive binding site of the α2 Na,K-ATPase.

ATP1A1 ATP1A2

3.03e-06261222258333
Pubmed

Na(+)/K)+)-ATPase α2-isoform preferentially modulates Ca2(+) transients and sarcoplasmic reticulum Ca2(+) release in cardiac myocytes.

ATP1A1 ATP1A2

3.03e-06261222739122
Pubmed

Identification of a specific role for the Na,K-ATPase alpha 2 isoform as a regulator of calcium in the heart.

ATP1A1 ATP1A2

3.03e-06261210360172
Pubmed

Na+/K+ ATPase α1 and α3 isoforms are differentially expressed in α- and γ-motoneurons.

ATP1A1 ATP1A3

3.03e-06261223761886
Pubmed

Ion pumps in polarized cells: sorting and regulation of the Na+, K+- and H+, K+-ATPases.

ATP1A1 ATP1A2

3.03e-06261211404365
Pubmed

Mice expressing ouabain-sensitive α1-Na,K-ATPase have increased susceptibility to pressure overload-induced cardiac hypertrophy.

ATP1A1 ATP1A2

3.03e-06261220952666
Pubmed

The family of human Na+,K+-ATPase genes. A partial nucleotide sequence related to the alpha-subunit.

ATP1A1 ATP1A3

3.03e-0626123030810
Pubmed

Ouabain-Sensitive alpha1 Na,K-ATPase enhances natriuretic response to saline load.

ATP1A1 ATP1A2

3.03e-06261218667729
Pubmed

Renovascular hypertension using a modified two-kidney, one-clip approach in mice is not dependent on the α1 or α2 Na-K-ATPase ouabain-binding site.

ATP1A1 ATP1A2

3.03e-06261221632957
Pubmed

Relationship between intracellular Na+ concentration and reduced Na+ affinity in Na+,K+-ATPase mutants causing neurological disease.

ATP1A2 ATP1A3

3.03e-06261224356962
Pubmed

Expression of alpha isoforms of the Na,K-ATPase in human heart.

ATP1A1 ATP1A2

3.03e-0626128391840
Pubmed

PGC-1α4 Interacts with REST to Upregulate Neuronal Genes and Augment Energy Consumption in Developing Cardiomyocytes.

ATP1A1 ATP1A2 ATP1A3

3.43e-061761336230906
Pubmed

RNG105 deficiency impairs the dendritic localization of mRNAs for Na+/K+ ATPase subunit isoforms and leads to the degeneration of neuronal networks.

ATP1A1 ATP1A2 ATP1A3

4.88e-061961320861386
Pubmed

Identification of different proteins binding to Na, K-ATPase α1 in LPS-induced ARDS cell model by proteomic analysis.

EEF2 NOP56 HADHB ATP1A1 ATP1A3

5.60e-0614461535681168
Pubmed

Targeted transgenic expression of beta(2)-adrenergic receptors to type II cells increases alveolar fluid clearance.

ATP1A1 ATP1A2

9.07e-06361211557593
Pubmed

Correlations between transmembrane 4 L6 family member 5 (TM4SF5), CD151, and CD63 in liver fibrotic phenotypes and hepatic migration and invasive capacities.

TM4SF5 CD151

9.07e-06361225033048
Pubmed

Isoform specificity of the Na/K-ATPase association and regulation by phospholemman.

ATP1A1 ATP1A2

9.07e-06361219638348
Pubmed

CpG island evolution in the mammalian DHRS4 gene cluster and its role in the regulation of gene transcription.

DHRS4 DHRS4L2

9.07e-06361227323117
Pubmed

Simultaneously reduced NKCC1 and Na,K-ATPase expression in murine cochlear lateral wall contribute to conservation of endocochlear potential following a sensorineural hearing loss.

ATP1A1 ATP1A2

9.07e-06361221094218
Pubmed

Effect of resistance training on Na,K pump and Na+/H+ exchange protein densities in muscle from control and patients with type 2 diabetes.

ATP1A1 ATP1A2

9.07e-06361214685860
Pubmed

In situ localization of sodium-potassium ATPase mRNA in developing mouse lung epithelium.

ATP1A1 ATP1A2

9.07e-0636127573462
Pubmed

Identification of peroxisomal proteins by using M13 phage protein VI phage display: molecular evidence that mammalian peroxisomes contain a 2,4-dienoyl-CoA reductase.

DHRS4 DHRS4L2

9.07e-06361210333503
Pubmed

Glycoprotein nonmetastatic melanoma protein B (GPNMB) promotes the progression of brain glioblastoma via Na+/K+-ATPase.

ATP1A1 ATP1A3

9.07e-06361227836549
Pubmed

Bioinformatic analysis of the human DHRS4 gene cluster and a proposed mechanism for its transcriptional regulation.

DHRS4 DHRS4L2

9.07e-06361220525226
Pubmed

Na,K-ATPase subunit isoforms in human reticulocytes: evidence from reverse transcription-PCR for the presence of alpha1, alpha3, beta2, beta3, and gamma.

ATP1A1 ATP1A2

9.07e-0636129159180
Pubmed

Reduction of all-trans-retinal in the mouse liver peroxisome fraction by the short-chain dehydrogenase/reductase RRD: induction by the PPAR alpha ligand clofibrate.

DHRS4 DHRS4L2

9.07e-06361212680773
Pubmed

Decreased content of ascorbic acid (vitamin C) in the brain of knockout mouse models of Na+,K+-ATPase-related neurologic disorders.

ATP1A2 ATP1A3

9.07e-06361233544780
Pubmed

Translationally controlled tumor protein interacts with the third cytoplasmic domain of Na,K-ATPase alpha subunit and inhibits the pump activity in HeLa cells.

ATP1A1 ATP1A2

9.07e-06361215383549
Pubmed

Purification of the human alpha2 Isoform of Na,K-ATPase expressed in Pichia pastoris. Stabilization by lipids and FXYD1.

ATP1A1 ATP1A2

9.07e-06361218052210
Pubmed

High glucose levels induce inhibition of Na,K-ATPase via stimulation of aldose reductase, formation of microtubules and formation of an acetylated tubulin/Na,K-ATPase complex.

ATP1A1 ATP1A2

9.07e-06361222565168
Pubmed

Na(+) pump alpha 2-isoform specifically couples to contractility in vascular smooth muscle: evidence from gene-targeted neonatal mice.

ATP1A1 ATP1A2

9.07e-06361214627611
Pubmed

Glycoprotein nonmetastatic melanoma protein B extracellular fragment shows neuroprotective effects and activates the PI3K/Akt and MEK/ERK pathways via the Na+/K+-ATPase.

ATP1A1 ATP1A3

9.07e-06361226988030
Pubmed

The alpha 1 isoform of Na,K-ATPase regulates cardiac contractility and functionally interacts and co-localizes with the Na/Ca exchanger in heart.

ATP1A1 ATP1A2

9.07e-06361215485817
Pubmed

Role of the asialoglycoprotein receptor in binding and entry of hepatitis C virus structural proteins in cultured human hepatocytes.

ASGR2 TG

9.07e-06361212477859
Pubmed

The highly conserved cardiac glycoside binding site of Na,K-ATPase plays a role in blood pressure regulation.

ATP1A1 ATP1A2

9.07e-06361216243970
Pubmed

IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes.

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

1.05e-057761415608191
Pubmed

Subunit isoform selectivity in assembly of Na,K-ATPase α-β heterodimers.

ATP1A1 ATP1A2

1.81e-05461222696220
Pubmed

Bioinformatic identification and characterization of new members of short-chain dehydrogenase/reductase superfamily.

DHRS4 DHRS4L2

1.81e-05461216406282
Pubmed

The Na,K-ATPase alpha4 isoform from humans has distinct enzymatic properties and is important for sperm motility.

ATP1A1 ATP1A4

1.81e-05461216861705
Pubmed

Na,K-ATPase expression in the mouse cochlea is not dependent on the mineralocorticoid receptor.

ATP1A1 ATP1A3

1.81e-05461211591489
Pubmed

Extracellular potassium dependence of the Na+-K+-ATPase in cardiac myocytes: isoform specificity and effect of phospholemman.

ATP1A1 ATP1A2

1.81e-05461219570895
Pubmed

Coordinated regulation of cardiac Na(+)/Ca (2+) exchanger and Na (+)-K (+)-ATPase by phospholemman (FXYD1).

ATP1A1 ATP1A2

1.81e-05461223224879
Pubmed

Molecular and functional evolution of human DHRS2 and DHRS4 duplicated genes.

DHRS4 DHRS4L2

1.81e-05461223036705
Pubmed

Chromosomal localization of human Na+, K+-ATPase alpha- and beta-subunit genes.

ATP1A1 ATP1A2 ATP1A3

2.02e-05306132842249
Pubmed

The complete nucleotide sequence of the human immunoglobulin heavy chain variable region locus.

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

2.04e-05916149841928
Pubmed

Chemical Crosslinking Mass Spectrometry Analysis of Protein Conformations and Supercomplexes in Heart Tissue.

EEF2 DHRS4 DHRS4L2 ACAA2 HADHB ATP1A1

2.54e-0533161629199018
Pubmed

Retinoschisin (RS1), the protein encoded by the X-linked retinoschisis gene, is anchored to the surface of retinal photoreceptor and bipolar cells through its interactions with a Na/K ATPase-SARM1 complex.

ATP1A2 ATP1A3

3.02e-05561217804407
Pubmed

Thyrotoxic periodic paralysis and polymorphisms of sodium-potassium ATPase genes.

ATP1A1 ATP1A2

3.02e-05561216430714
Pubmed

Isoform-specific Na,K-ATPase and membrane cholesterol remodeling in motor endplates in distinct mouse models of myodystrophy.

ATP1A1 ATP1A2

3.02e-05561232293933
Pubmed

Ankyrin-B coordinates the Na/K ATPase, Na/Ca exchanger, and InsP3 receptor in a cardiac T-tubule/SR microdomain.

ATP1A1 ATP1A2

3.02e-05561216292983
Cytoband14q32.33

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20 IGHV3-30-5 IGHV3-30-3

5.62e-0722860614q32.33
Cytoband2p23

NCOA1 HADHB

2.26e-04176022p23
Cytoband12q24.13

SDSL RPH3A

4.94e-042560212q24.13
Cytoband1q23.2

ATP1A2 ATP1A4

9.72e-04356021q23.2
Cytoband14q11.2

SLC25A21 DHRS4 DHRS4L2

1.72e-0318060314q11.2
GeneFamilyATPase Na+/K+ transporting subunits

ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.66e-0974941208
GeneFamilyImmunoglobulin heavy locus at 14q32.33

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20 IGHV3-30-5 IGHV3-30-3 IGHV3-43D

6.73e-07187497349
GeneFamilySolute carriers

SLC9A9 SLC25A21 SLC9A2 SLC41A3 SLC17A1 SLC37A2 SLC7A10 SLC47A2

9.96e-06395498752
GeneFamilyShort chain dehydrogenase/reductase superfamily

HSD3B7 DHRS4 DHRS4L2

1.14e-0376493743
GeneFamilyRing finger proteins|Fanconi anemia complementation groups|Protein phosphatase 1 regulatory subunits|BRCA1 A complex|BRCA1 B complex|BRCA1 C complex

BRIP1 FANCM

1.33e-0320492548
CoexpressionXU_CREBBP_TARGETS_DN

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20 ATP1A1

1.43e-0756575MM642
CoexpressionGSE5589_WT_VS_IL10_KO_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_DN

CA12 EEF2 SLC37A2 ACAA2 ATP1A2 SLC7A10

4.81e-06200576M6652
CoexpressionBUSSLINGER_DUODENAL_LATE_IMMATURE_ENTEROCYTES

HLA-DRA TM4SF5 ACAA2 HADHB ATP1A1

4.18e-05177575M40028
CoexpressionGSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_DN

SLC9A9 TNFSF10 ASGR2 NUP210 RPH3A

6.78e-05196575M6111
CoexpressionYAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_6

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

7.29e-05102574MM872
CoexpressionGSE339_CD4POS_VS_CD4CD8DN_DC_IN_CULTURE_DN

SDSL DHRS4 NCOA1 TM4SF5 ACAA2

7.46e-05200575M5124
CoexpressionGSE411_100MIN_VS_400MIN_IL6_STIM_MACROPHAGE_UP

SLC41A3 HLA-DRA LPIN2 ACAA2 FANCM

7.46e-05200575M5997
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HSD3B7 SLC9A9 TNFSF10 LPIN2 PKHD1 CD151

2.00e-0719458670185c0b8e0f4e896645b17a243482ba3cdf4a5d
ToppCelldroplet-Liver-Npc-21m-Epithelial-Hepatocyte_(Midlobular)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SDSL SLC25A21 DHRS4 NMUR1 ACAA2

1.21e-061435850cd332c128710291a39957d3da22953352f5c382
ToppCellT_cells-ISG-high_CD4+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

TNFSF10 ASGR2 TRIM56 LPIN2 PARP12

3.64e-06179585af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Fibcd1-Excitatory_Neuron.Slc17a7.Fibcd1-Lypd1_(CA1_Principal_cells_(Anterior))|Hippocampus / BrainAtlas - Mouse McCarroll V32

CA12 SLC9A2 ATP1A4 GPR151

4.44e-068458452d167614afa9b056f2934142d3250fe5e70e806
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TNFSF10 SLC17A1 LPIN2 PKHD1 SLC47A2

4.75e-061895853b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCellHSPCs-Ery_prog.|HSPCs / Lineage and Cell class

SDSL EEF2 SLC25A21 SLC41A3 LPIN2

4.75e-0618958537d2c45debed1564a40a1085b8b310c50923b9e7
ToppCellCOVID-19-kidney-CNT|kidney / Disease (COVID-19 only), tissue and cell type

CA12 SLC9A2 PKHD1 SNTG1 ATP1A1

5.12e-06192585d32ae226d95b4b6adb99d14b602be09b661d4cd9
ToppCellHSPCs-Ery_prog.|World / Lineage and Cell class

SDSL SLC25A21 DHRS4 NOP56 LPIN2

5.25e-06193585484c2e0daedc6cb0d50d164add8c1658123a60f9
ToppCellMild-CD8+_T_activated|World / Disease group and Cell class

TNFSF10 TRIM56 LPIN2 JAML PARP12

5.66e-0619658579632190e44fcef9d7c11d9b9e37f2ebf0e6e255
ToppCellTracheal-10x5prime-Immune_Lymphocytic-B|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20 HLA-DRA

5.81e-061975852662138671262b30508c5759038bcdcfe6551696
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-B-B_cell|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20 HLA-DRA

5.81e-0619758576465bb2408c7c75f694e8f7cf1a606b796afc3a
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DHRS4 TNFSF10 SLC17A1 ACAA2 SLC47A2

5.95e-0619858572733b6149b797ac11cc108bc80428b77fbbba78
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DHRS4 TNFSF10 SLC17A1 ACAA2 SLC47A2

5.95e-06198585f23559ce6072e3c323f6791ff95269271b0f7ff1
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CA12 SLC9A2 PKHD1 SNTG1 ATP1A1

6.10e-061995853cd6383c50ce342fe5c175e2e50784d634a90e80
ToppCellTCGA-Bile_Duct|World / Sample_Type by Project: Shred V9

ASGR2 BAAT PKHD1 C5

3.34e-05140584ca8a0ccbc2f501b759864fe9bb06dc8b44b6b31f
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SLC25A21 BRIP1 ATP1A4 JAML

3.53e-05142584e160f35b3c18e77c4107fe96db5f56227c91785e
ToppCelldroplet-Liver-Npc-21m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SDSL DHRS4 NMUR1 ACAA2

3.94e-0514658424e63124116b9a6796ae0495fc69dc6b6af28c38
ToppCelldroplet-Liver-Npc-21m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SDSL DHRS4 NMUR1 ACAA2

3.94e-05146584ae43d418492177546b7f85afffb4287d40815f88
ToppCell367C-Myeloid-Macrophage-SPP1+_Macrophage_4|367C / Donor, Lineage, Cell class and subclass (all cells)

SDSL ASGR2 HLA-DRA SLC37A2

4.73e-051535843570dd844d6479425bf6f62129f88efa45553775
ToppCelltumor_Lung-Myeloid_cells-Pleural_Mac|tumor_Lung / Location, Cell class and cell subclass

SLC9A2 ASGR2 HLA-DRA JAML

5.91e-051625849ac3242511315224ed94582aca9e9a3786cd01a0
ToppCell367C-Lymphocytic-Plasma_cell-|367C / Donor, Lineage, Cell class and subclass (all cells)

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

6.64e-05167584f2185eb72f0137136f6d71af2a70168fded6c940
ToppCellnormal_Lymph_Node-Myeloid_cells-Pleural_Mac|Myeloid_cells / Location, Cell class and cell subclass

BRIP1 TNFSF10 ASGR2 JAML

6.64e-05167584820472887f43b42ae7e44513ca3d5465fb4f71a7
ToppCell367C-Lymphocytic-Plasma_cell|367C / Donor, Lineage, Cell class and subclass (all cells)

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

6.64e-051675845e768cf24699893e05d1bcb1c92dba2336943a64
ToppCellBAL-Mild-Lymphocyte-B|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

6.96e-05169584307571e57c3bfdf15f0fe1a8b36585e8e4f8a207
ToppCellfacs-Marrow-KLS-24m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DHRS4 TM4SF5 JAML SLC7A10

6.96e-05169584d6ad3b637de2935c656aad47ad82d6e8a8bd1227
ToppCellfacs-Marrow-KLS-24m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DHRS4 TM4SF5 JAML SLC7A10

6.96e-0516958460ef186518d0dc63dbded2a77c65cfe3129df754
ToppCell5'-Adult-Appendix-Hematopoietic-Plasma_cells-IgA_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

7.62e-0517358468bcc0eee15df9cf3516c641709154301bd7b38f
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

7.62e-051735847e6bfe85f60834f317941b70d6e0dc3bd527d293
ToppCellCOPD-Lymphoid-B_Plasma|World / Disease state, Lineage and Cell class

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

7.96e-05175584d73ee324479172501481b54967a0f3bd870fcf3a
ToppCell5'-Adult-Appendix-Hematopoietic-Plasma_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

8.69e-05179584ba7744b903abfc28b39a00472661f152e9ae39fd
ToppCellCOVID-19-kidney-PCT-S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

CA12 SLC17A1 PKHD1 SLC47A2

8.88e-05180584358923e4228035a3e90e2957392089219e90dcd7
ToppCellCOVID-19-kidney-tDL|COVID-19 / Disease (COVID-19 only), tissue and cell type

CA12 SLC17A1 PKHD1 SLC47A2

8.88e-05180584864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

9.07e-05181584e47664a264a2c37390d1668ce04eef2e0172f4cb
ToppCellfacs-Marrow-T-cells-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A9 SLC41A3 ATP1A1 ATP1A3

9.07e-051815847286700396676fdc41d9723979b8b408177aceb9
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_monocyte_(14)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TNFSF10 ASGR2 HLA-DRA JAML

9.07e-051815843457c1d431db4282be5a6243119e48960748ede7
ToppCellCOVID-19-kidney-Stressed_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

CA12 SLC17A1 PKHD1 SLC47A2

9.07e-051815846980ea624151da32b7f537f263e40fcb87a02e81
ToppCellB_cells-ISG-high_B_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

TNFSF10 HLA-DRA LPIN2 PARP12

9.47e-05183584dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCellMild_COVID-19-B_cell|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

9.47e-05183584dea119e2988e954475f557f0bbe12556a83e81a4
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

TNFSF10 SLC17A1 PKHD1 SLC47A2

9.67e-0518458451ed1ebfdef45149541917c66cbacad87072e51f
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

9.87e-051855840fff2608f507e019ebb69c27e58fd5be3b049bef
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

9.87e-0518558479edc1eeb7b5b9123961ac3ecf398ee68d9dddb9
ToppCellCOVID-19-kidney-Mito-rich_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

CA12 SLC17A1 PKHD1 SLC47A2

9.87e-051855841bbc2ba8a20f72f61981b1301cdd6018cdd9150d
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

9.87e-0518558408bc817908076734d66f2805cb954141f2cc5a18
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

9.87e-051855841704a12153a9b107bf03ecccd1a036cf61334d7a
ToppCell3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ASGR2 HLA-DRA NUP210 JAML

1.01e-04186584bec4767eaca28e41da373274704895eba75063e2
ToppCellwk_08-11-Hematologic-Myeloid-Cycling_DC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ASGR2 HLA-DRA SLC37A2 JAML

1.01e-04186584de1f0bc5dbf6dc0e716f5ebbf2bbcfe249811c54
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TNFSF10 SLC17A1 PKHD1 SLC47A2

1.01e-04186584f28d72b47624b69a580b4429e2be560a26898591
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-B_cells-Immature_B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGHV3-33 IGHV3-30 IGHV3-20 HLA-DRA

1.01e-04186584459a7e97bbac2b2cd253aa4ab38d0e4ae6191e8b
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_immature_monocyte2_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ASGR2 HLA-DRA SLC37A2 JAML

1.01e-04186584cb4ea1bc1427230070e9696baeda7de241c354b1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CA12 SLC9A2 SNTG1 ATP1A1

1.01e-04186584b3358e0fa6d845c81e94d56c8575f016621d28ff
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TNFSF10 SLC17A1 PKHD1 SLC47A2

1.01e-04186584b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TNFSF10 SLC17A1 PKHD1 SLC47A2

1.03e-041875849d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CCN4 CD151 ATP1A2 RPH3A

1.03e-04187584db771e952f71a12886c2dbc77c6cd07054ef809a
ToppCellT_cells-ISG-high_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

TNFSF10 TRIM56 LPIN2 PARP12

1.05e-041885846f8946d4710f6e32c937213f99b790b098b8819c
ToppCell3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid-Monocytes|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ASGR2 HLA-DRA NUP210 JAML

1.07e-04189584a010f3e4da6e9bb23b0b9a7f82ad5cee4e607ecd
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CA12 SLC9A2 PKHD1 SNTG1

1.07e-0418958490aae7e806882bebfad78a78e9a16cf56af3ecd4
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TNFSF10 SLC17A1 PKHD1 SLC47A2

1.07e-0418958428b502611829e4a24caff2562545c7db97686099
ToppCellCOVID-19-kidney-PCT-S2|kidney / Disease (COVID-19 only), tissue and cell type

TNFSF10 SLC17A1 PKHD1 SLC47A2

1.07e-041895840be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

1.09e-0419058479ee6d10dfbb775da149a1104da5823cf63bbb46
ToppCellfacs-Marrow-KLS-24m-Hematologic-MPP_Fraction_B|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SDSL HSD3B7 DHRS4 NOP56

1.09e-041905843bd422755ce1d9854dbfebca7b28afa1d03d595c
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

1.09e-0419058418762ce78ed0b206ade19e1c8ff76a2647489f68
ToppCell5'-Adult-LargeIntestine-Hematopoietic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

1.12e-04191584d1d30279ed4612b4f62c225d9eabf0b8a7a09d11
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TNFSF10 SLC17A1 PKHD1 SLC47A2

1.12e-041915843c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TNFSF10 SLC17A1 PKHD1 SLC47A2

1.12e-041915841c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TNFSF10 SLC17A1 PKHD1 SLC47A2

1.12e-041915841cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCellCOVID-19-Lymphoid-Plasma,_B_cells|Lymphoid / Condition, Lineage and Cell class

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

1.12e-04191584bcdadf83cb9653f9cc2a281e7c1095fe8f79173c
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

1.14e-041925843dddfc93c3c954c4416c7c1f1f161e4d1dcc1233
ToppCellCOVID-19-Lymphoid-Plasma,_B_cells|COVID-19 / Condition, Lineage and Cell class

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

1.16e-04193584bffd97a73365e1dd23ff3b0320b4860f04ec091a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC9A9 HLA-DRA SLC37A2 JAML

1.16e-041935843e3d7cb3e7242ec9c9677e07e303835649852b52
ToppCellChildren_(3_yrs)-Immune-monocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLC9A9 ASGR2 HLA-DRA JAML

1.16e-0419358458e1930a1d80ad3729ab9604ac8ebf7308232a3d
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

1.16e-041935845c5543e7c83ecea44d23521246592c0301044173
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CA12 SLC17A1 PKHD1 ATP1A1

1.16e-041935843866667dd221612589ae50f5c52f73a183a49ce6
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

1.16e-0419358434f6c13884fdf7f8a87f942fcb36a58cfac3f65d
ToppCellTracheal-10x5prime-Immune_Lymphocytic-B-B_plasma|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

1.16e-04193584282b47dae6043eabb1e13d41d91c07b5ec21cd65
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.0.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SDSL HSD3B7 HLA-DRA SLC37A2

1.19e-04194584fa50c77a6d6b083cdafdb07243bc68b894977487
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_immature_monocyte1_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ASGR2 HLA-DRA SLC37A2 JAML

1.19e-04194584fad22d5cf62016cad979e6943e357106d8d2a4b4
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-B-B_plasma|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

1.19e-041945846ef4aeb8d8e35e4df58ff2a8256caa2113291de9
ToppCellTracheal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_plasmacytoid|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SDSL HLA-DRA JAML

1.19e-0473583582faedb369a099d0acf1565413e6b3ca2cfc564
ToppCellCOVID-19_Severe-Classical_Monocyte-cMono_4|Classical_Monocyte / Disease condition and Cell class

TNFSF10 HLA-DRA TRIM56 PARP12

1.21e-041955841992a1673b7213e25f3c76ac77da35c57daceddd
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC9A9 HLA-DRA SLC37A2 JAML

1.21e-0419558442bfdff88da1d07828c0ad65d412fb1752f0cee4
ToppCellBronchial-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

1.21e-0419558413f4ee21568fd747608412d33559d10561dbb3c8
ToppCellBiopsy_Other_PF-Immune-Plasma_cells|Biopsy_Other_PF / Sample group, Lineage and Cell type

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

1.21e-04195584d0305c6a68c9e361507b04db94f86873085d49b3
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CA12 SLC9A2 SNTG1 ATP1A1

1.21e-041955843f517c6fc372bdcaf45b3af373414f13cbebd4ba
ToppCellCOVID-19_Severe-Classical_Monocyte-cMono_4|COVID-19_Severe / Disease condition and Cell class

TNFSF10 HLA-DRA TRIM56 PARP12

1.21e-04195584787ea9f38ad8e2a836222ca97f4d927f7e79517d
ToppCellTracheal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

1.21e-04195584df009b18898c10686f75cf72b4ec0eff18f5bb50
ToppCellBronchial-10x5prime-Immune_Lymphocytic-B-B_plasma|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

1.23e-04196584c38e7f533c619afe008de0e99042f7180c2da918
ToppCellPCW_05-06-Hematologic_Myeloid|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ASGR2 HLA-DRA SLC37A2 JAML

1.23e-04196584b2aee2f67da373a10b0c25e7797e30e3811543a8
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-B|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IGHV3-43 IGHV3-30 IGHV3-20 NUP210

1.23e-04196584fc67d8aad1ec4d7f98ffe44fb103e230b9b42c35
ToppCellMild|World / Disease group and Cell class

TNFSF10 TRIM56 JAML PARP12

1.23e-041965845e4ed4a5a437cfa002b92775992a791e27aa4c27
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DHRS4 SLC17A1 TM4SF5 SLC47A2

1.23e-041965844ebcaac758ed01d918de9c1cd383a84457b615f3
ToppCellCOVID_vent-Lymphocytic-Plasma_cell-IgM_Plasmablast|COVID_vent / Disease condition, Lineage, Cell class and subclass

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

1.23e-04196584026a06d8d2089806823e6f6453d3ede84ae93bc6
ToppCellBiopsy_IPF-Immune-Plasma_cells|Biopsy_IPF / Sample group, Lineage and Cell type

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

1.23e-04196584a1b6a8000b86efcb07843998aa3a49bb1f54bcda
ToppCellMild-CD4+_T_activated|World / Disease group and Cell class

TNFSF10 TRIM56 LPIN2 PARP12

1.23e-04196584417b4fc2e4388f34c410576131b02936f93e46b6
ToppCellPBMC-Control-cDC_3|Control / Compartment, Disease Groups and Clusters

EEF2 HLA-DRA TRIM56 NUP210

1.23e-0419658409d197b321ff9f13c0672ea059c850845b0dbbd5
ToppCellBronchial-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

1.23e-04196584fec21383435779bf4c632decd3d29c6ca7baebfb
ToppCellBronchial-10x5prime-Immune_Lymphocytic-B|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

1.26e-0419758488b29d205237f07a9a26cc15a1cf4ed4816a4c4b
ToppCellBiopsy_Control_(H.)-Immune-Plasma_cells|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

IGHV3-43 IGHV3-33 IGHV3-30 IGHV3-20

1.26e-04197584275f38ed7e477000e864cecf9b7d49ae134c3b6a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC9A9 HLA-DRA SLC37A2 JAML

1.26e-04197584d95565652ca318a2298d6918d54ba6367e9560f4
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

LPIN2 PKHD1 C5 ATP1A1

1.26e-041975843d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCellwk_15-18-Hematologic-Myeloid-S100A12-lo_cla._mono.|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ASGR2 HLA-DRA SLC37A2 JAML

1.26e-041975845bf4d964a9ee82002d3bc9ba1f020902eb96de7a
ComputationalGenes in the cancer module 249.

BAAT ACAA2 HADHB

5.09e-0522363MODULE_249
Drug22,23-dihydrobufalin

ATP1A1 ATP1A2 ATP1A3

1.26e-075543CID000195392
Drug3-acetylstrophanthin

ATP1A1 ATP1A2 ATP1A3

1.26e-075543CID003082282
Drugthevetin A

ATP1A1 ATP1A2 ATP1A3

1.26e-075543CID000441873
Drugamyl nitrite

SLC9A9 SLC9A2 ATP1A1 ATP1A2 ATP1A3

1.63e-0753545CID000008053
DrugETH157

ATP1A1 ATP1A2 ATP1A3

2.51e-076543CID000563154
Drugdihydrodigitoxigenin

ATP1A1 ATP1A2 ATP1A3

4.38e-077543CID000107549
Drugbumetanide

CA12 SLC9A9 SLC9A2 SLC17A1 ATP1A1 ATP1A2 ATP1A3

6.10e-07209547CID000002471
DrugR-TrHOCCoA

HSD3B7 ACAA2 HADHB

1.05e-069543CID000440690
DrugAC1L99QU

HSD3B7 ACAA2 HADHB

1.05e-069543CID000440676
Drugtrimethaphan

SLC9A9 SLC9A2 ATP1A1 ATP1A2 ATP1A3

1.39e-0681545CID000023576
Drugsodium

CA12 SLC9A9 SLC9A2 DHRS4 ATP7B MOCS3 SLC17A1 ATP1A1 ATP1A2 ATP1A3 ATP1A4 SLC7A10

1.65e-069445412CID000000923
Drugouabagenin

ATP1A1 ATP1A2 ATP1A3

2.05e-0611543CID000010497
Drugpoly(vinylidene fluoride

SLC9A9 SLC9A2 CD151 ATP1A2 ATP1A3

2.22e-0689545CID000006369
DrugA-32686

ATP1A1 ATP1A2 ATP1A3

3.55e-0613543CID000004951
DrugAC1L99R9

BAAT ACAA2 HADHB

4.51e-0614543CID000440685
DrugHDMA

ATP1A1 ATP1A2 ATP1A3

8.38e-0617543CID000131092
Drugacetylstrophanthidin

ATP1A1 ATP1A2 ATP1A3

1.00e-0518543CID000006062
DrugAC1L1F3Q

ATP1A1 ATP1A2 ATP1A3

1.00e-0518543CID000003068
DrugNSC 234205

ATP1A1 ATP1A2 ATP1A3

1.00e-0518543CID000010104
Drugsodium iodide

ATP1A1 ATP1A2 ATP1A3 TG

1.17e-0559544CID000005238
DrugCymarigenen

ATP1A1 ATP1A2 ATP1A3

1.40e-0520543CID000005303
DrugAC1NST54

ATP1A1 ATP1A2 ATP1A3

1.63e-0521543CID005315525
Druglevulinic acid

ACAA2 HADHB

1.65e-053542CID000011578
DrugNSC9567

SLC9A9 SLC9A2 ATP1A1 ATP1A2 ATP1A3

2.10e-05141545CID000003001
Drugcardenolide

ATP1A1 ATP1A2 ATP1A3

2.16e-0523543CID000016142
Drughydride

CA12 HSD3B7 SLC9A9 SLC9A2 DHRS4 SLC17A1 HADHB ATP1A2 ATP1A3 SLC47A2

2.31e-058355410CID000000783
DrugAC1L1947

BAAT ACAA2 HADHB

3.15e-0526543CID000000383
DrugAS701

ATP1A2 ATP1A3

3.30e-054542CID000133528
DrugAC1L4X7Z

ACAA2 HADHB

3.30e-054542CID000193896
DrugBenazepril-d5

SLC9A9 SLC9A2 ATP1A2 ATP1A3

3.36e-0577544CID000002311
DrugAmiloride

SLC9A2 TNFSF10 ATP1A1 SLC47A2

3.54e-0578544ctd:D000584
Drugfurosemide

CA12 SLC17A1 C5 ATP1A1 ATP1A2 ATP1A3

4.39e-05272546CID000003440
Drugnalidixic acid

SLC9A9 SLC9A2 SLC17A1 ATP1A1 ATP1A2 ATP1A3

4.86e-05277546CID000004421
Drugglycine

SDSL PDPR BAAT NCOA1 SLC7A10

5.00e-05169545CID000000750
Drug2-chloro-6-phenylhexanoate

ACAA2 HADHB

5.50e-055542CID000195566
DrugFr 6

SLC25A21 TG

5.50e-055542CID000449013
DrugAC1L8Y60

SLC9A9 SLC9A2 SLC17A1 ATP1A1

5.94e-0589544CID000410009
Drug2-methylacetoacetate

ACAA2 HADHB

8.23e-056542CID000150996
Drug4-hydroxyvalerate

ACAA2 HADHB

8.23e-056542CID000114539
Drugsodium; lithium

SLC9A2 ATP1A1 ATP1A3

8.52e-0536543CID012725854
DrugLasalocid sodium salt [25999-20-6]; Down 200; 6.6uM; HL60; HT_HG-U133A

SLC9A2 TNFSF10 ASGR2 NCOA1 NMUR1

9.61e-051945453021_DN
DrugDiazoxide [364-98-7]; Up 200; 17.4uM; PC3; HT_HG-U133A

NOP56 SLC41A3 GPR37 NUP210 ATP1A3

1.01e-041965452052_UP
DrugRapamycin; Down 200; 0.1uM; PC3; HT_HG-U133A

CA12 MOCS3 GPR37 NUP210 PARP12

1.08e-041995451242_DN
Drugdihydropyrone

ATP1A2 ATP1A3

1.15e-047542CID000010760
DrugN-(2-methyl-4,5-bis(methylsulfonyl)benzoyl)guanidine

ATP1A2 ATP1A3

1.15e-047542ctd:C481648
Drug(E)-heptadec-2-enoic acid

ACAA2 HADHB

1.15e-047542CID005282747
DrugNsc638719

EEF2 SLC25A21

1.15e-047542CID005459174
DrugCID6432277

ATP1A1 ATP1A2 ATP1A3

1.26e-0441543CID006432277
Drugglutaconyl-CoA

ATP1A2 ATP1A3

1.53e-048542CID009543049
Drug3alpha, 7alpha-dihydroxy-5beta-cholestanoyl-CoA

ACAA2 HADHB

1.53e-048542CID000440420
DrugAC1MI0E8

ACAA2 HADHB

1.53e-048542CID003036008
DrugHydroflumethiazide

CA12 ATP1A1

1.53e-048542DB00774
Drugphenidone

C5 ATP1A2 ATP1A3

1.78e-0446543CID000007090
DrugDigoxin

ATP1A1 ATP1A2 ATP1A3

1.78e-0446543ctd:D004077
DrugOuabain

ACAA2 ATP1A1 ATP1A2 ATP1A3

1.83e-04119544ctd:D010042
DrugAC1MBZB6

ATP1A1 ATP1A3

1.97e-049542CID002733620
Drug3-oxo-octanoyl-coenzyme A

ACAA2 HADHB

1.97e-049542CID000440608
DrugAC1L99M9

ACAA2 HADHB

1.97e-049542CID000440604
DrugAC1L99MF

ACAA2 HADHB

1.97e-049542CID000440606
DrugAmmonia

SLC9A2 ATP1A2 ATP1A3

2.02e-0448543ctd:D000641
Drugcarbonyl cyanide m-chlorophenylhydrazone

ATP1A1 ATP1A2 ATP1A3 TG

2.21e-04125544CID000002603
Drug6-methyluracil

ACAA2 HADHB

2.45e-0410542CID000012283
Drug2-Methylacetoacetyl-CoA

ACAA2 HADHB

2.45e-0410542CID000000053
Drug2-bromododecanoate

ACAA2 HADHB

2.45e-0410542CID000066980
Drughydroxyl radicals

CA12 SDSL HSD3B7 EEF2 PDPR ATP7B BAAT HADHB ATP1A1 ATP1A2 ATP1A3

2.61e-0413415411CID000000961
DrugMetribolone

DLG5 EEF2 BRIP1 ATP7B NCOA1 ATP1A1

2.81e-04382546ctd:D015741
DrugCGP-37157

EEF2 TNFSF10

3.00e-0411542CID000002688
Drug3-hydroxyhexanoate

ACAA2 HADHB

3.00e-0411542CID000151492
DrugAC1L9LQQ

CA12 SLC9A2 C5

3.37e-0457543CID000448224
DrugNSC89595

ATP1A1 ATP1A2 ATP1A3

3.37e-0457543CID000002464
Drugdibutyryl cyclic 3',5'-AMP

EEF2 SLC25A21 ATP1A1 ATP1A2 ATP1A3 ATP1A4 TG

3.45e-04561547CID000002460
Drughydroflumethiazide

CA12 ATP1A1

3.59e-0412542CID000003647
Drugnilic acid

ACAA2 HADHB

3.59e-0412542CID000160471
Drug3-ketohexanoyl-CoA

ACAA2 HADHB

3.59e-0412542CID000440610
Drugrubidium

SLC9A9 ATP1A2 ATP1A3

4.12e-0461543CID000105153
Drug3-chloropropionyl-CoA

ACAA2 HADHB

4.24e-0413542CID000125892
DrugC22:0

ACAA2 HADHB

4.24e-0413542CID000008215
Drugpoly(3-hydroxybutyrate-co-3-hydroxyvalerate

ACAA2 HADHB

4.24e-0413542CID000107801
DrugAC1L1GU8

ATP1A1 ATP1A2 ATP1A3

4.32e-0462543CID000003843
Diseasefamilial hemiplegic migraine (implicated_via_orthology)

ATP1A1 ATP1A2 ATP1A3 ATP1A4

3.49e-107544DOID:0060178 (implicated_via_orthology)
Diseasenervous system disease (implicated_via_orthology)

ATP1A1 ATP1A2 ATP1A3 ATP1A4

4.90e-0912544DOID:863 (implicated_via_orthology)
Diseaseabdominal adipose tissue measurement

PKHD1 ATP1A1 ATP1A3 ATP1A4

2.74e-0653544EFO_0803316
DiseaseALTERNATING HEMIPLEGIA OF CHILDHOOD 1

ATP1A2 ATP1A3

3.29e-062542C3549447
Diseasealternating hemiplegia of childhood (is_implicated_in)

ATP1A2 ATP1A3

3.29e-062542DOID:0050635 (is_implicated_in)
DiseaseAlternating hemiplegia of childhood

ATP1A2 ATP1A3

1.97e-054542C0338488
Diseasecups of coffee per day measurement

ATP1A1 ATP1A3 ATP1A4

5.46e-0540543EFO_0006782
DiseaseFanconi anemia (implicated_via_orthology)

BRIP1 FANCM

9.14e-058542DOID:13636 (implicated_via_orthology)
DiseaseWNT1-inducible-signaling pathway protein 1 measurement

CCN4 TG

1.47e-0410542EFO_0008321
DiseaseN-acetylhistidine measurement

SLC17A1 TRIM56

1.79e-0411542EFO_0800022
Diseaseautoimmune thyroiditis (is_implicated_in)

HLA-DRA TG

2.14e-0412542DOID:7188 (is_implicated_in)
Diseasehyperhomocysteinemia (biomarker_via_orthology)

ATP1A1 ATP1A2

2.14e-0412542DOID:9279 (biomarker_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

ATP1A1 ATP1A2 ATP1A3 ATP1A4

2.29e-04163544DOID:1826 (implicated_via_orthology)
Diseasebreast carcinoma (is_marker_for)

BRIP1 ATP7B NCOA1

2.44e-0466543DOID:3459 (is_marker_for)
Diseasesquamous cell carcinoma, multiple keratinocyte carcinoma susceptibility measurement, basal cell carcinoma

BRIP1 PKHD1

2.53e-0413542EFO_0000707, EFO_0004193, EFO_0007932
Diseaselipid metabolism disorder (implicated_via_orthology)

LPIN2 HADHB

3.40e-0415542DOID:3146 (implicated_via_orthology)
DiseaseMammary Carcinoma, Human

EEF2 BRIP1 ATP7B TNFSF10 NCOA1 HADHB

3.86e-04525546C4704874
DiseaseMammary Neoplasms, Human

EEF2 BRIP1 ATP7B TNFSF10 NCOA1 HADHB

3.86e-04525546C1257931
DiseaseMammary Neoplasms

EEF2 BRIP1 ATP7B TNFSF10 NCOA1 HADHB

3.94e-04527546C1458155
DiseaseBreast Carcinoma

EEF2 BRIP1 ATP7B TNFSF10 NCOA1 HADHB

4.40e-04538546C0678222
Diseasealcohol use disorder (implicated_via_orthology)

ATP1A1 ATP1A2 ATP1A3 ATP1A4

4.52e-04195544DOID:1574 (implicated_via_orthology)
DiseaseBone marrow hypocellularity

BRIP1 FANCM

4.94e-0418542C1855710
Diseasemonocyte count

TNFSF10 HLA-DRA NCOA1 ATP1A1 ATP1A3 ATP1A4 JAML SLC7A10 PARP12

6.03e-041320549EFO_0005091
DiseaseDegenerative polyarthritis

EEF2 ACAA2 ATP1A3

6.69e-0493543C0029408
DiseaseOsteoarthrosis Deformans

EEF2 ACAA2 ATP1A3

6.69e-0493543C0086743
DiseaseNeoplasm Metastasis

CCN4 EEF2 TNFSF10 NCOA1

6.75e-04217544C0027627
Diseasecolon adenocarcinoma (is_marker_for)

CA12 EEF2

9.60e-0425542DOID:234 (is_marker_for)
DiseaseFanconi Anemia

BRIP1 FANCM

9.60e-0425542C0015625
DiseasePancytopenia

BRIP1 FANCM

1.04e-0326542C0030312
DiseaseAcute monocytic leukemia

BRIP1 FANCM

1.04e-0326542C0023465
DiseaseMiller Dieker syndrome

BRIP1 FANCM

1.29e-0329542C0265219
Diseasechloride measurement

HLA-DRA RPH3A

1.29e-0329542EFO_0009284
Diseaseadult onset asthma

SLC9A2 HLA-DRA SLC7A10

1.33e-03118543EFO_1002011
DiseaseAbnormality of radial ray

BRIP1 FANCM

1.67e-0333542C4228778
Diseasebullous pemphigoid

HLA-DRA LPIN2

1.78e-0334542EFO_0007187

Protein segments in the cluster

PeptideGeneStartEntry
GSGVGVVSVCQGVQI

BAAT

226

Q14032
CTIIIGNIIGSGIFI

SLC7A10

46

Q9NS82
LVVICVTGSQSEGHG

ASGR2

71

P07307
GQTAILVAIDGVLCG

ATP7B

1176

P35670
VQGTRNVIEACVQTG

HSD3B7

106

Q9H2F3
AIGVCAQVVGVGCVL

CCN4

111

O95388
LQGEGLSVTGTVCHV

DHRS4

76

Q9BTZ2
TTGVGLIASGQCDVI

HADHB

146

P55084
LIASGQCDVIVAGGV

HADHB

151

P55084
TCQALGEQVIALSVG

NUP210

711

Q8TEM1
QIVAGGSAGLVEICL

SLC25A21

16

Q9BQT8
LQGEGLSVTGTVCHV

DHRS4L2

76

Q6PKH6
NCQTGGVIAEILRGV

NOP56

111

O00567
GVQCEVQLVESGGVV

IGHV3-43D

16

P0DP04
GVQCQVQLVESGGGV

IGHV3-30-5

16

P0DP03
TVLGIIFTNGNCVAE

MAGEB10

206

Q96LZ2
FVVGAVGNGLTCLVI

NMUR1

71

Q9HB89
GVQCQVQLVESGGGV

IGHV3-30-3

16

P0DP02
IVEGCQRQGAIVAVT

ATP1A1

701

P05023
GQSVGVQGEAACVSI

FAM13B

451

Q9NYF5
GIQQGIIEGEFAICI

FANCM

351

Q8IYD8
QVQVCTAAGLSLGII

CA12

291

O43570
TQAQVVICGGGITGT

PDPR

41

Q8NCN5
GVIQGGALSSICTQI

DLG5

1886

Q8TDM6
GVQCEVQLVESGGGV

IGHV3-20

16

A0A0C4DH32
VCLVGFVGNLCVIGI

GPR151

46

Q8TDV0
GVQCEVQLVESGGVV

IGHV3-43

16

A0A0B4J1X8
VVGEVTQVLCAAGGA

PARP12

6

Q9H0J9
VGALLLSVCQTVSQG

BRIP1

676

Q9BX63
FVVIQVCNGLVQTTG

SLC37A2

146

Q8TED4
NCVEGTARGIVIATG

ATP1A2

246

P50993
CLSVVIFGTGIIGNL

GPR37

266

O15354
GVGISNTGICVADTV

C5

801

P01031
ENVVCALGLTVGLVG

HLA-DRA

216

P01903
GVQCQVQLVESGGGV

IGHV3-30

16

P01768
IVEGCQRQGAIVAVT

ATP1A3

691

P13637
CGNIVGLVGVDQFLV

EEF2

466

P13639
RVIGAVGIGIACVQV

CD151

221

P48509
VTCGIGVREVILTNG

SPACA1

86

Q9HBV2
GVVTGVLGCLQALEV

MOCS3

246

O95396
GVQCQVQLVESGGGV

IGHV3-33

16

P01772
STQQGGLIVGIIRCV

RPH3A

561

Q9Y2J0
FVNVCGVSVGVGLSS

SLC47A2

76

Q86VL8
GLTGIVAVLFCGVTQ

SLC9A9

331

Q8IVB4
FQVIAVDGVCTGIIQ

SNTG1

231

Q9NSN8
GGNQLVIIVGIVCAT

JAML

271

Q86YT9
QVFADVQCTVNLVGG

NCOA1

1391

Q15788
VVVCRAVQGAAQGIV

SLC17A1

136

Q14916
VICGVGGNLVAIQTS

SLC41A3

321

Q96GZ6
VIITAVTENFGCLGG

PKHD1

1736

P08F94
LTSVVVIVCGGNNIN

SDSL

301

Q96GA7
NCVEGTARGIVIATG

ATP1A4

256

Q13733
VGSGTCITQVGQQLF

C11orf87

41

Q6NUJ2
ACIGGGQGIAVIIQS

ACAA2

381

P42765
SIGIGVSLFGICQIE

SLC9A2

181

Q9UBY0
VVTTQVELGGCSRQG

SPDYC

31

Q5MJ68
VLCGIQLVNATIGVF

TM4SF5

171

O14894
VQGGPSLGQTCVLIV

TNFSF10

6

P50591
GFVLTQVQGGAIICG

TG

1736

P01266
GLGAVADCVGINVTV

MST1R

886

Q04912
NSVVICDGLGQVVGE

TRIM56

656

Q9BRZ2
GINQATLSGCIDVIV

LPIN2

21

Q92539