| GeneOntologyMolecularFunction | cadherin binding | MRE11 FASN CTNNA1 CTNNA2 SEPTIN7 GOLGA3 NOTCH3 LRRFIP1 | 3.26e-04 | 339 | 101 | 8 | GO:0045296 |
| GeneOntologyMolecularFunction | beta-catenin binding | AMER1 APC2 PXN CTNNA1 CTNNA2 | 3.60e-04 | 120 | 101 | 5 | GO:0008013 |
| GeneOntologyMolecularFunction | keratin filament binding | KRT74 FAM83H | 3.75e-04 | 6 | 101 | 2 | GO:1990254 |
| GeneOntologyCellularComponent | cell cortex | EPS8 IQSEC2 RYR1 NSMF PXN RIMBP2 TNFAIP2 CTNNA2 SEPTIN7 SEPTIN12 | 1.37e-05 | 371 | 102 | 10 | GO:0005938 |
| GeneOntologyCellularComponent | presynaptic active zone cytoplasmic component | IQSEC2 RIMBP2 CTNNA2 | 1.86e-04 | 23 | 102 | 3 | GO:0098831 |
| Domain | Alpha_catenin | CTNNA1 CTNNA2 | 1.69e-04 | 4 | 100 | 2 | IPR001033 |
| Domain | VINCULIN_1 | CTNNA1 CTNNA2 | 1.69e-04 | 4 | 100 | 2 | PS00663 |
| Domain | Vinculin_CS | CTNNA1 CTNNA2 | 1.69e-04 | 4 | 100 | 2 | IPR000633 |
| Domain | Vinculin | CTNNA1 CTNNA2 | 2.81e-04 | 5 | 100 | 2 | PF01044 |
| Domain | Autophagy-rel_C | ATG2A VPS13B | 2.81e-04 | 5 | 100 | 2 | IPR015412 |
| Domain | ATG_C | ATG2A VPS13B | 2.81e-04 | 5 | 100 | 2 | PF09333 |
| Domain | Vinculin/catenin | CTNNA1 CTNNA2 | 5.86e-04 | 7 | 100 | 2 | IPR006077 |
| Domain | Chorein_N | ATG2A VPS13B | 7.78e-04 | 8 | 100 | 2 | PF12624 |
| Domain | VPS13_N | ATG2A VPS13B | 7.78e-04 | 8 | 100 | 2 | IPR026854 |
| Domain | G_SEPTIN_dom | SEPTIN7 SEPTIN12 | 2.13e-03 | 13 | 100 | 2 | IPR030379 |
| Domain | Septin | SEPTIN7 SEPTIN12 | 2.13e-03 | 13 | 100 | 2 | PF00735 |
| Domain | G_SEPTIN | SEPTIN7 SEPTIN12 | 2.13e-03 | 13 | 100 | 2 | PS51719 |
| Domain | Septin | SEPTIN7 SEPTIN12 | 2.48e-03 | 14 | 100 | 2 | IPR016491 |
| Domain | Acyl_Trfase/lysoPLipase | FASN PNPLA6 | 3.66e-03 | 17 | 100 | 2 | IPR016035 |
| Pubmed | Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders. | KIF21B CACNA1E IQSEC2 APC2 GRM3 GATAD2B STOX2 FXR1 ANAPC1 EIF4A2 ANKRD17 RIMBP2 CTNNA1 CTNNA2 SEPTIN7 GOLGA3 LRRFIP1 SH3BP5 | 3.99e-10 | 963 | 102 | 18 | 28671696 |
| Pubmed | Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity. | MRE11 ZSWIM8 SREK1 RFC4 PDHX GATAD2B FAM83H HMG20B TTC7A FXR1 PNPLA6 SH3TC1 ANAPC1 NFRKB ANKRD17 DNA2 LRRC41 NIN | 4.05e-09 | 1116 | 102 | 18 | 31753913 |
| Pubmed | E-cadherin interactome complexity and robustness resolved by quantitative proteomics. | MRE11 SRCIN1 FAM83H TTC7A FASN EHBP1L1 PXN CTNNA1 CTNNA2 SEPTIN7 GOLGA3 NOTCH3 LRRFIP1 | 1.20e-08 | 565 | 102 | 13 | 25468996 |
| Pubmed | Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes. | MRE11 TNIP2 SMARCAL1 CBFA2T3 CIC GATAD2B HMG20B FASN FXR1 SH3TC1 ANAPC1 ANKRD17 L3MBTL3 NOTCH3 LRRC41 | 3.16e-08 | 857 | 102 | 15 | 25609649 |
| Pubmed | KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility. | CPEB2 SLC12A6 EPS8 IQSEC2 SRCIN1 GRM3 PDHX PITPNM1 FASN FXR1 PNPLA6 RIMBP2 CTNNA1 CTNNA2 SEPTIN7 CROCC GOLGA3 SDHA LRRFIP1 | 3.24e-08 | 1431 | 102 | 19 | 37142655 |
| Pubmed | Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. | CACNA1E RASGRF1 SRCIN1 PITPNM1 FAM163B RIMBP2 CTNNA1 CTNNA2 SEPTIN7 | 8.96e-07 | 347 | 102 | 9 | 17114649 |
| Pubmed | Epidermal development requires ninein for spindle orientation and cortical microtubule organization. | CTNNA1 CTNNA2 NOTCH3 NIN | 9.92e-07 | 26 | 102 | 4 | 30923192 |
| Pubmed | The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei. | MRE11 EPS8 WDR36 SREK1 CIC GATAD2B HMG20B PNPLA6 ANAPC1 SUPT6H NFRKB PXN ANKRD17 MPHOSPH8 CTNNA2 CROCC SDHA | 1.63e-06 | 1497 | 102 | 17 | 31527615 |
| Pubmed | NF2 deficiency promotes tumorigenesis and metastasis by destabilizing adherens junctions. | PXN CTNNA1 CTNNA2 | 2.03e-06 | 9 | 102 | 3 | 12695331 |
| Pubmed | Switching of α-Catenin From Epithelial to Neuronal Type During Lens Epithelial Cell Differentiation. | PRX CTNNA1 CTNNA2 | 2.03e-06 | 9 | 102 | 3 | 28692740 |
| Pubmed | A balance between elongation and trimming regulates telomere stability in stem cells. | MRE11 SMARCAL1 DNA2 | 2.90e-06 | 10 | 102 | 3 | 27918544 |
| Pubmed | Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease. | ZSWIM8 LRSAM1 IQSEC2 APC2 PEG3 NSMF EIF4A2 VPS35L DLEU7 CTNNA1 SEPTIN7 GOLGA3 SDHA LRRFIP1 SH3BP5 | 5.16e-06 | 1285 | 102 | 15 | 35914814 |
| Pubmed | Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. | SLC12A6 AMER1 SDCCAG8 SRCIN1 PTPN18 DNAAF5 ARHGAP6 PNPLA6 SH3TC1 SUPT6H VPS35L ANKRD17 CROCC VPS13B NOTCH3 LRRC41 | 6.90e-06 | 1489 | 102 | 16 | 28611215 |
| Pubmed | The human cytoplasmic dynein interactome reveals novel activators of motility. | EPS8 AMER1 SEC24A SDCCAG8 CNTRL PKD1L1 ATG2A PDHX FAM83H PXN SEPTIN7 NIN | 7.86e-06 | 853 | 102 | 12 | 28718761 |
| Pubmed | Phosphoproteomic analysis of the developing mouse brain. | KIF21B FAT4 SRCIN1 CIC GATAD2B CTNNA1 CTNNA2 | 8.48e-06 | 246 | 102 | 7 | 15345747 |
| Pubmed | FXR1 is a novel MRE11-binding partner and participates in oxidative stress responses. | MRE11 FXR1 | 8.52e-06 | 2 | 102 | 2 | 32211858 |
| Pubmed | CEP110 and ninein are located in a specific domain of the centrosome associated with centrosome maturation. | CNTRL NIN | 8.52e-06 | 2 | 102 | 2 | 11956314 |
| Pubmed | Monomeric α-catenin links cadherin to the actin cytoskeleton. | CTNNA1 CTNNA2 | 8.52e-06 | 2 | 102 | 2 | 23417122 |
| Pubmed | Exon sharing of a novel human zinc-finger gene, ZIM2, and paternally expressed gene 3 (PEG3). | PEG3 ZIM2 | 8.52e-06 | 2 | 102 | 2 | 10708526 |
| Pubmed | Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells. | MRE11 WDR36 GATAD2B FXR1 SUPT6H EIF4A2 CTNNA1 DNA2 L3MBTL3 | 1.03e-05 | 469 | 102 | 9 | 27634302 |
| Pubmed | A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. | ZSWIM8 AMER1 TNIP2 SEC24A IQSEC2 KCMF1 ATG2A BLZF1 HMG20B PXN ZC3H12C SEPTIN7 SH3BP5 | 1.11e-05 | 1038 | 102 | 13 | 26673895 |
| Pubmed | Identification of Novel Nuclear Factor of Activated T Cell (NFAT)-associated Proteins in T Cells. | MRE11 RFC4 GATAD2B FXR1 SUPT6H SDHA | 1.48e-05 | 178 | 102 | 6 | 27637333 |
| Pubmed | Large-scale characterization of HeLa cell nuclear phosphoproteins. | MRE11 CIC GATAD2B PITPNM1 FASN PNPLA6 ANAPC1 NFRKB ANKRD17 CTNNA1 LRRFIP1 | 1.75e-05 | 774 | 102 | 11 | 15302935 |
| Pubmed | Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling. | CACNA1E IQSEC2 SRCIN1 GRM3 PITPNM1 CTNNA2 SEPTIN7 | 2.00e-05 | 281 | 102 | 7 | 28706196 |
| Pubmed | In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker. | SLC12A6 CACNA1E AMER1 KRT74 CNTRL SREK1 PRX RPS6KC1 CDCA2 FASN FXR1 TCHHL1 EIF4A2 MPHOSPH8 ABCC2 | 2.01e-05 | 1442 | 102 | 15 | 35575683 |
| Pubmed | A dual-activity topoisomerase complex regulates mRNA translation and turnover. | ENGASE SEMA7A ATG2A CIC RYR1 FAM83H FASN EHBP1L1 PNPLA6 SH3TC1 PXN TNFAIP2 SDHA | 2.14e-05 | 1105 | 102 | 13 | 35748872 |
| Pubmed | A high-throughput approach for measuring temporal changes in the interactome. | MRE11 SEC24A LRSAM1 KCMF1 RFC4 DNAAF5 FASN EHBP1L1 COPS8 NFRKB PXN CTNNA1 SEPTIN7 CROCC LRRFIP1 | 2.23e-05 | 1455 | 102 | 15 | 22863883 |
| Pubmed | Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription. | MRE11 ZSWIM8 WDR36 FASN FXR1 ANAPC1 SUPT6H ANKRD17 CTNNA1 SDHA | 2.30e-05 | 653 | 102 | 10 | 22586326 |
| Pubmed | Expression of Apc2 during mouse development. | APC2 NOTCH3 | 2.55e-05 | 3 | 102 | 2 | 15018807 |
| Pubmed | Leucine zipper domain of HIV-1 gp41 interacted specifically with alpha-catenin. | CTNNA1 CTNNA2 | 2.55e-05 | 3 | 102 | 2 | 11883950 |
| Pubmed | Alpha-catenin is essential in intestinal adenoma formation. | CTNNA1 CTNNA2 | 2.55e-05 | 3 | 102 | 2 | 17989230 |
| Pubmed | An autoinhibited structure of α-catenin and its implications for vinculin recruitment to adherens junctions. | CTNNA1 CTNNA2 | 2.55e-05 | 3 | 102 | 2 | 23589308 |
| Pubmed | Structure of the dimerization and beta-catenin-binding region of alpha-catenin. | CTNNA1 CTNNA2 | 2.55e-05 | 3 | 102 | 2 | 10882138 |
| Pubmed | Alteration of E-cadherin and alpha N-catenin immunoreactivity in the mouse spinal cord following peripheral axotomy. | CTNNA1 CTNNA2 | 2.55e-05 | 3 | 102 | 2 | 9370228 |
| Pubmed | The cytoplasmic domain of HIV-1 gp41 interacts with the carboxyl-terminal region of alpha-catenin. | CTNNA1 CTNNA2 | 2.55e-05 | 3 | 102 | 2 | 10420987 |
| Pubmed | Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex. | AMER1 KCMF1 SREK1 RFC4 PDHX FASN ANAPC1 CTNNA1 SEPTIN7 SDHA LRRFIP1 | 2.63e-05 | 809 | 102 | 11 | 32129710 |
| Pubmed | Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. | KIF21B SRCIN1 ATG2A STOX2 SUPT6H ANKRD17 DNA2 L3MBTL3 NIN | 2.66e-05 | 529 | 102 | 9 | 14621295 |
| Pubmed | RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling. | PDHX FASN PXN DMPK GOLGA3 LRRFIP1 | 3.02e-05 | 202 | 102 | 6 | 24639526 |
| Pubmed | Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation. | CIC HMG20B FASN ANAPC1 PXN ANKRD17 L3MBTL3 GOLGA3 | 3.34e-05 | 418 | 102 | 8 | 34709266 |
| Pubmed | Protein interactome reveals converging molecular pathways among autism disorders. | ZSWIM8 TNIP2 LRSAM1 CNTRL APC2 FXR1 L3MBTL3 GOLGA3 NOTCH3 | 4.14e-05 | 560 | 102 | 9 | 21653829 |
| Pubmed | Septin6 and Septin7 GTP binding proteins regulate AP-3- and ESCRT-dependent multivesicular body biogenesis. | LRSAM1 SEPTIN7 | 5.09e-05 | 4 | 102 | 2 | 25380047 |
| Pubmed | Regulation of stereocilia length by myosin XVa and whirlin depends on the actin-regulatory protein Eps8. | EPS8 TYRP1 | 5.09e-05 | 4 | 102 | 2 | 21236676 |
| Pubmed | Recessive mutations in muscle-specific isoforms of FXR1 cause congenital multi-minicore myopathy. | RYR1 FXR1 | 5.09e-05 | 4 | 102 | 2 | 30770808 |
| Pubmed | Bidirectional transcription from human LRRTM2/CTNNA1 and LRRTM1/CTNNA2 gene loci leads to expression of N-terminally truncated CTNNA1 and CTNNA2 isoforms. | CTNNA1 CTNNA2 | 5.09e-05 | 4 | 102 | 2 | 21708131 |
| Pubmed | N-cadherin mediates cortical organization in the mouse brain. | CTNNA1 CTNNA2 | 5.09e-05 | 4 | 102 | 2 | 17222817 |
| Pubmed | Mouse alpha N-catenin: two isoforms, specific expression in the nervous system, and chromosomal localization of the gene. | CTNNA1 CTNNA2 | 5.09e-05 | 4 | 102 | 2 | 8174789 |
| Pubmed | Heterocellular interaction enhances recruitment of alpha and beta-catenins and ZO-2 into functional gap-junction complexes and induces gap junction-dependant differentiation of mammary epithelial cells. | CTNNA1 CTNNA2 | 5.09e-05 | 4 | 102 | 2 | 18775424 |
| Pubmed | Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice. | MRE11 SREK1 RFC4 FASN ANAPC1 EIF4A2 CTNNA1 TNFAIP2 SEPTIN7 | 5.57e-05 | 582 | 102 | 9 | 20467437 |
| Pubmed | Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. | MRE11 AMER1 CNTRL PEG3 RPS6KC1 FXR1 EIF4A2 VPS35L NFRKB ANKRD17 DNA2 VPS13B | 8.12e-05 | 1084 | 102 | 12 | 11544199 |
| Pubmed | Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics. | CACNA1E EPS8 ZSWIM8 SEMA7A RPS6KC1 FXR1 SUPT6H NFRKB | 8.16e-05 | 475 | 102 | 8 | 31040226 |
| Pubmed | Differential expression of alpha-E-catenin and alpha-N-catenin in the developing cerebral cortex. | CTNNA1 CTNNA2 | 8.47e-05 | 5 | 102 | 2 | 16457793 |
| Pubmed | The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species. | CTNNA1 CTNNA2 | 8.47e-05 | 5 | 102 | 2 | 2788574 |
| Pubmed | SEPT12 orchestrates the formation of mammalian sperm annulus by organizing core octameric complexes with other SEPT proteins. | SEPTIN7 SEPTIN12 | 8.47e-05 | 5 | 102 | 2 | 25588830 |
| Pubmed | Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule. | CTNNA1 CTNNA2 | 8.47e-05 | 5 | 102 | 2 | 2349235 |
| Pubmed | Alpha-catenin is a molecular switch that binds E-cadherin-beta-catenin and regulates actin-filament assembly. | CTNNA1 CTNNA2 | 8.47e-05 | 5 | 102 | 2 | 16325583 |
| Pubmed | Wnt-1-dependent regulation of local E-cadherin and alpha N-catenin expression in the embryonic mouse brain. | CTNNA1 CTNNA2 | 8.47e-05 | 5 | 102 | 2 | 7925023 |
| Pubmed | PEG3 controls lipogenesis through ACLY. | PEG3 FASN | 8.47e-05 | 5 | 102 | 2 | 34048454 |
| Pubmed | FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia. | KIF21B LRSAM1 KCMF1 SRCIN1 SREK1 COPS8 CROCC2 CTNNA1 | 1.11e-04 | 497 | 102 | 8 | 36774506 |
| Pubmed | LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells. | ZSWIM8 AMER1 RFC4 PDHX PNPLA6 SUPT6H ANKRD17 CTNNA2 GOLGA3 | 1.13e-04 | 639 | 102 | 9 | 23443559 |
| Pubmed | The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers. | MRE11 WDR36 SREK1 RFC4 CIC GATAD2B CDCA2 NFRKB MPHOSPH8 SEPTIN7 L3MBTL3 | 1.15e-04 | 954 | 102 | 11 | 36373674 |
| Pubmed | BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair. | MRE11 DNA2 | 1.27e-04 | 6 | 102 | 2 | 21325134 |
| Pubmed | Deletion in Catna2, encoding alpha N-catenin, causes cerebellar and hippocampal lamination defects and impaired startle modulation. | CTNNA1 CTNNA2 | 1.27e-04 | 6 | 102 | 2 | 12089526 |
| Pubmed | The Hippo signaling pathway is required for salivary gland development and its dysregulation is associated with Sjogren's syndrome. | CTNNA1 CTNNA2 | 1.27e-04 | 6 | 102 | 2 | 24080911 |
| Pubmed | Switching of alpha-catenin from alphaE-catenin in the cortical ventricular zone to alphaN-catenin II in the intermediate zone. | CTNNA1 CTNNA2 | 1.27e-04 | 6 | 102 | 2 | 16185771 |
| Pubmed | Isolation of murine SPT5 homologue: completion of the isolation and characterization of human and murine homologues of yeast chromatin structural protein complex SPT4, SPT5, and SPT6. | RYR1 SUPT6H | 1.27e-04 | 6 | 102 | 2 | 9480761 |
| Pubmed | The conditional inactivation of the beta-catenin gene in endothelial cells causes a defective vascular pattern and increased vascular fragility. | CTNNA1 CTNNA2 | 1.27e-04 | 6 | 102 | 2 | 12975353 |
| Pubmed | Web-based, participant-driven studies yield novel genetic associations for common traits. | BNC2 TYRP1 TCHHL1 | 1.37e-04 | 34 | 102 | 3 | 20585627 |
| Pubmed | Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair. | MRE11 ZSWIM8 AMER1 PEG3 RFC4 GATAD2B FASN FXR1 COPS8 ANAPC1 CTNNA1 SDHA LRRC41 | 1.45e-04 | 1335 | 102 | 13 | 29229926 |
| Pubmed | Establishment of paternal genomic imprinting in mouse prospermatogonia analyzed by nuclear transfer. | RASGRF1 PEG3 | 1.77e-04 | 7 | 102 | 2 | 25232016 |
| Pubmed | The protein tyrosine phosphatase Pez is a major phosphatase of adherens junctions and dephosphorylates beta-catenin. | CTNNA1 CTNNA2 | 1.77e-04 | 7 | 102 | 2 | 12808048 |
| Pubmed | Expression and cell membrane localization of catenins during mouse preimplantation development. | CTNNA1 CTNNA2 | 1.77e-04 | 7 | 102 | 2 | 8853988 |
| Pubmed | The tumor-suppressor function of E-cadherin. | CTNNA1 CTNNA2 | 1.77e-04 | 7 | 102 | 2 | 9837810 |
| Pubmed | The cell adhesion molecule M-cadherin is not essential for muscle development and regeneration. | CTNNA1 CTNNA2 | 1.77e-04 | 7 | 102 | 2 | 12052883 |
| Pubmed | alphaE-catenin is not a significant regulator of beta-catenin signaling in the developing mammalian brain. | CTNNA1 CTNNA2 | 1.77e-04 | 7 | 102 | 2 | 18397997 |
| Pubmed | Adhesion protein VSIG1 is required for the proper differentiation of glandular gastric epithelia. | CTNNA1 CTNNA2 | 1.77e-04 | 7 | 102 | 2 | 21991385 |
| Pubmed | Defining the human deubiquitinating enzyme interaction landscape. | MRE11 WDR36 ATG2A RFC4 COPS8 SUPT6H EIF4A2 NFRKB ANKRD17 RIMBP2 NIN | 1.80e-04 | 1005 | 102 | 11 | 19615732 |
| Pubmed | FBXO42 facilitates Notch signaling activation and global chromatin relaxation by promoting K63-linked polyubiquitination of RBPJ. | SMARCAL1 HMG20B COPS8 SUPT6H L3MBTL3 | 2.11e-04 | 183 | 102 | 5 | 36129980 |
| Pubmed | A central chaperone-like role for 14-3-3 proteins in human cells. | AMER1 SEC24A IQSEC2 CIC FAM83H CDCA2 STOX2 FXR1 DSTYK ANKRD17 | 2.25e-04 | 861 | 102 | 10 | 36931259 |
| Pubmed | Functional analysis of ectodermal β-catenin during external genitalia formation. | CTNNA1 CTNNA2 | 2.36e-04 | 8 | 102 | 2 | 23480356 |
| Pubmed | 3D-structured illumination microscopy provides novel insight into architecture of human centrosomes. | CNTRL NIN | 2.36e-04 | 8 | 102 | 2 | 23213374 |
| Pubmed | TGF-beta3 is required for the adhesion and intercalation of medial edge epithelial cells during palate fusion. | CTNNA1 CTNNA2 | 2.36e-04 | 8 | 102 | 2 | 12068957 |
| Pubmed | DYNLL1 binds to MRE11 to limit DNA end resection in BRCA1-deficient cells. | MRE11 DNA2 | 2.36e-04 | 8 | 102 | 2 | 30464262 |
| Pubmed | The genes coding for alpha and beta catenin (Catna1 and Catnb) and plakoglobin (Jup) map to mouse chromosomes 18, 9, and 11, respectively. | CTNNA1 CTNNA2 | 2.36e-04 | 8 | 102 | 2 | 7626889 |
| Pubmed | Transcription-coupled nucleotide excision repair is coordinated by ubiquitin and SUMO in response to ultraviolet irradiation. | GATAD2B FXR1 SUPT6H SDHA | 2.38e-04 | 102 | 102 | 4 | 31722399 |
| Pubmed | Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins. | CPEB2 KIF21B WDR36 SREK1 FASN FXR1 EIF4A2 CTNNA1 NIN | 2.83e-04 | 723 | 102 | 9 | 34133714 |
| Pubmed | Proteome-scale mapping of binding sites in the unstructured regions of the human proteome. | APC2 ATG2A BLZF1 CIC PRX ARHGAP6 LRRFIP1 | 2.83e-04 | 430 | 102 | 7 | 35044719 |
| Pubmed | Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome. | EPS8 IQSEC2 PDHX STOX2 CTNNA2 | 2.96e-04 | 197 | 102 | 5 | 36604605 |
| Pubmed | Expression of catenins during mouse embryonic development and in adult tissues. | CTNNA1 CTNNA2 | 3.03e-04 | 9 | 102 | 2 | 8821035 |
| Pubmed | Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma. | MRE11 WDR36 RFC4 FAM83H FASN FXR1 PNPLA6 ANKRD17 CTNNA1 SEPTIN7 SDHA LRRFIP1 | 3.19e-04 | 1257 | 102 | 12 | 36526897 |
| Pubmed | Reciprocal interaction between SIRT6 and APC/C regulates genomic stability. | WDR36 RPS6KC1 CDCA2 FXR1 ANAPC1 SUPT6H ANKRD17 | 3.25e-04 | 440 | 102 | 7 | 34244565 |
| Pubmed | A unique set of centrosome proteins requires pericentrin for spindle-pole localization and spindle orientation. | CNTRL NIN | 3.77e-04 | 10 | 102 | 2 | 25220058 |
| Pubmed | Lima1 mediates the pluripotency control of membrane dynamics and cellular metabolism. | CTNNA1 CTNNA2 | 3.77e-04 | 10 | 102 | 2 | 35105859 |
| Pubmed | Alpha N-catenin deficiency causes defects in axon migration and nuclear organization in restricted regions of the mouse brain. | CTNNA1 CTNNA2 | 3.77e-04 | 10 | 102 | 2 | 16691566 |
| Pubmed | AAV-mediated intramuscular delivery of myotubularin corrects the myotubular myopathy phenotype in targeted murine muscle and suggests a function in plasma membrane homeostasis. | LAMA2 RYR1 | 3.77e-04 | 10 | 102 | 2 | 18434328 |
| Pubmed | Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair. | MRE11 RFC4 GATAD2B FXR1 ANKRD17 NIN | 3.78e-04 | 321 | 102 | 6 | 32098917 |
| Pubmed | Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms. | MRE11 WDR36 CNTRL FXR1 VPS35L DNA2 GOLGA3 LRRC41 NIN | 3.84e-04 | 754 | 102 | 9 | 33060197 |
| Pubmed | Global landscape of HIV-human protein complexes. | KIF21B SDCCAG8 TYRP1 COPS8 ANAPC1 ANKRD17 SDHA | 4.08e-04 | 457 | 102 | 7 | 22190034 |
| Pubmed | Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation. | CPEB2 SEC24A CIC FAM83H DNAAF5 PNPLA6 ANKRD17 | 4.08e-04 | 457 | 102 | 7 | 32344865 |
| Pubmed | H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids. | MRE11 WDR36 RFC4 CIC GATAD2B HMG20B CDCA2 ANAPC1 SUPT6H NFRKB MPHOSPH8 L3MBTL3 | 4.13e-04 | 1294 | 102 | 12 | 30804502 |
| Pubmed | The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1. | KCMF1 ANAPC1 SUPT6H ANKRD17 LRRC41 | 4.14e-04 | 212 | 102 | 5 | 33853758 |
| GeneFamily | Septins | SEPTIN7 SEPTIN12 | 7.98e-04 | 13 | 59 | 2 | 732 |
| Coexpression | GSE14769_UNSTIM_VS_360MIN_LPS_BMDM_UP | CPEB2 MRE11 SDCCAG8 RFC4 PTPN18 PNPLA6 LEPROTL1 VPS13B | 1.10e-06 | 200 | 101 | 8 | M3509 |
| Coexpression | HEVNER_CORTICAL_PLATE_POSTMITOTIC_PROJECTION_NEURONS | CACNA1E EPS8 FAT4 SEMA7A RASGRF1 NSMF NIN | 1.67e-06 | 147 | 101 | 7 | MM414 |
| Coexpression | GSE360_CTRL_VS_L_DONOVANI_MAC_DN | IQSEC2 PDHX SUSD5 VPS35L LEPROTL1 PXN SH3BP5 | 1.23e-05 | 199 | 101 | 7 | M5159 |
| Coexpression | ZHONG_PFC_C3_ASTROCYTE | CACNA1E SRCIN1 CBFA2T3 CIC RPS6KC1 STOX2 PNPLA6 RIMBP2 GOLGA3 | 2.00e-05 | 389 | 101 | 9 | M39102 |
| Disease | facial morphology measurement | TBX15 BNC2 FAT4 SREK1 MAGEF1 TYRP1 ARHGAP6 FAM163B ANAPC1 L3MBTL3 VPS13B | 6.01e-07 | 466 | 101 | 11 | EFO_0007841 |
| Disease | complex cortical dysplasia with other brain malformations (is_implicated_in) | APC2 CTNNA2 | 6.93e-05 | 4 | 101 | 2 | DOID:0090131 (is_implicated_in) |
| Disease | Malignant neoplasm of breast | MRE11 SMARCAL1 APC2 LAMA2 RFC4 CIC FASN FXR1 EIF4A2 L3MBTL3 VPS13B NOTCH3 LRRFIP1 | 7.70e-05 | 1074 | 101 | 13 | C0006142 |
| Disease | susceptibility to mononucleosis measurement | TBX15 CPEB2 FAT4 WDR36 | 9.42e-05 | 69 | 101 | 4 | EFO_0008403 |
| Disease | Abnormality of refraction | LRRC38 RASGRF1 PKD1L1 LAMA2 GRM3 TYRP1 SUSD5 RIMBP2 CTNNA2 NIN | 1.06e-04 | 673 | 101 | 10 | HP_0000539 |
| Disease | pack-years measurement, Barrett's esophagus | SLC12A6 VPS35L | 1.15e-04 | 5 | 101 | 2 | EFO_0000280, EFO_0006526 |
| Disease | Cystic kidney | FAT4 SDCCAG8 | 1.72e-04 | 6 | 101 | 2 | C0022679 |
| Disease | Squamous cell carcinoma of esophagus | FAT4 FASN ABCC2 NOTCH3 | 3.24e-04 | 95 | 101 | 4 | C0279626 |
| Disease | nephronophthisis (implicated_via_orthology) | SDCCAG8 CNTRL | 4.11e-04 | 9 | 101 | 2 | DOID:12712 (implicated_via_orthology) |
| Disease | Cystic Kidney Diseases | FAT4 SDCCAG8 | 6.25e-04 | 11 | 101 | 2 | C1691228 |
| Disease | lobe attachment | TBX15 KIF21B BNC2 FAT4 CTNNA2 | 7.43e-04 | 207 | 101 | 5 | EFO_0007667 |
| Disease | Congenital muscular dystrophy | LAMA2 RYR1 | 7.49e-04 | 12 | 101 | 2 | cv:C0699743 |
| Disease | Intellectual Disability | CACNA1E SDCCAG8 APC2 CIC PDHX FASN CTNNA2 | 8.84e-04 | 447 | 101 | 7 | C3714756 |
| Disease | Myopia | RASGRF1 LAMA2 | 1.18e-03 | 15 | 101 | 2 | C0027092 |
