Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

ATP8B3 ANO6 ANO1 ANO3

1.35e-0551574GO:0140303
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine phosphatase activity

PTPRK PTPRU PTPRT

1.46e-0517573GO:0005001
GeneOntologyMolecularFunctiontransmembrane receptor protein phosphatase activity

PTPRK PTPRU PTPRT

1.46e-0517573GO:0019198
GeneOntologyMolecularFunctionintracellularly calcium-gated channel activity

ANO6 ANO1 ANO3

2.43e-0520573GO:0141147
GeneOntologyMolecularFunctionintracellularly calcium-gated chloride channel activity

ANO6 ANO1 ANO3

2.43e-0520573GO:0005229
GeneOntologyMolecularFunctionphospholipid scramblase activity

ANO6 ANO1 ANO3

3.75e-0523573GO:0017128
GeneOntologyMolecularFunctionphospholipid transporter activity

ATP8B3 ANO6 ANO1 ANO3

5.92e-0574574GO:0005548
GeneOntologyMolecularFunction3'-5'-RNA exonuclease activity

REXO2 HELZ2 CNOT2

1.60e-0437573GO:0000175
GeneOntologyMolecularFunctionRNA exonuclease activity, producing 5'-phosphomonoesters

REXO2 HELZ2 CNOT2

2.02e-0440573GO:0016896
GeneOntologyMolecularFunctionRNA exonuclease activity

REXO2 HELZ2 CNOT2

2.87e-0445573GO:0004532
GeneOntologyMolecularFunctionligand-gated monoatomic anion channel activity

ANO6 ANO1 ANO3

3.93e-0450573GO:0099095
GeneOntologyMolecularFunctionvoltage-gated chloride channel activity

ANO6 ANO1

4.33e-0411572GO:0005247
GeneOntologyMolecularFunctiongamma-catenin binding

PTPRK PTPRT

5.19e-0412572GO:0045295
GeneOntologyMolecularFunction3'-5' exonuclease activity

REXO2 HELZ2 CNOT2

7.06e-0461573GO:0008408
GeneOntologyMolecularFunctionexonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

REXO2 HELZ2 CNOT2

7.40e-0462573GO:0016796
GeneOntologyMolecularFunctionvoltage-gated monoatomic anion channel activity

ANO6 ANO1

1.06e-0317572GO:0008308
GeneOntologyMolecularFunctionchloride channel activity

ANO6 ANO1 ANO3

1.91e-0386573GO:0005254
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

TRPV1 ANO6 ANO1 ANO3

2.24e-03193574GO:0015276
GeneOntologyMolecularFunctionexonuclease activity

REXO2 HELZ2 CNOT2

2.31e-0392573GO:0004527
GeneOntologyMolecularFunctionlipid transporter activity

ATP8B3 ANO6 ANO1 ANO3

2.37e-03196574GO:0005319
GeneOntologyMolecularFunctionligand-gated channel activity

TRPV1 ANO6 ANO1 ANO3

2.41e-03197574GO:0022834
GeneOntologyMolecularFunctioncalcium-activated cation channel activity

ANO6 ANO1

2.68e-0327572GO:0005227
GeneOntologyMolecularFunctionprotein tyrosine phosphatase activity

PTPRK PTPRU PTPRT

3.19e-03103573GO:0004725
GeneOntologyMolecularFunctionmonoatomic anion channel activity

ANO6 ANO1 ANO3

3.19e-03103573GO:0005253
GeneOntologyMolecularFunctionmonoatomic ion-gated channel activity

ANO6 ANO1

3.53e-0331572GO:0022839
GeneOntologyMolecularFunctionchannel activity

GJA3 TRPV1 ANO6 ANO1 TRPV6 ANO3

3.74e-03525576GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

GJA3 TRPV1 ANO6 ANO1 TRPV6 ANO3

3.78e-03526576GO:0022803
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

HCAR3 TRPV1 CSF2RB PTPRK CXCR4 ADGRL1 ADGRE5 PTPRU CRHR1 PTPRT

4.58e-0313535710GO:0004888
GeneOntologyMolecularFunctionmetalloendopeptidase activity

BMP1 TLL2 PAPPA

4.89e-03120573GO:0004222
GeneOntologyMolecularFunctionbeta-catenin binding

PTPRK PTPRU PTPRT

4.89e-03120573GO:0008013
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

ANO6 ANO1 ANO3

5.48e-03125573GO:0015108
GeneOntologyMolecularFunctionRNA nuclease activity

REXO2 HELZ2 CNOT2

6.91e-03136573GO:0004540
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

TRPV1 ANO6 ANO1

7.49e-03140573GO:0099094
GeneOntologyMolecularFunctionendopeptidase activity

BMP1 TLL2 RHBDL1 PAPPA CTSL

7.56e-03430575GO:0004175
GeneOntologyMolecularFunctionhydrolase activity, acting on ester bonds

REXO2 PTPRK HELZ2 PROCA1 PTPRU CNOT2 PTPRT

7.83e-03807577GO:0016788
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

ANO6 ANO1 ANO3

9.21e-03151573GO:0008509
GeneOntologyMolecularFunctionproteoglycan binding

APP CTSL

9.33e-0351572GO:0043394
GeneOntologyBiologicalProcessdetection of temperature stimulus

TRPV1 CXCR4 ANO1 ANO3

2.32e-0633594GO:0016048
GeneOntologyBiologicalProcessdetection of temperature stimulus involved in sensory perception of pain

TRPV1 CXCR4 ANO1

5.52e-0526593GO:0050965
GeneOntologyBiologicalProcesscalcium activated phospholipid scrambling

ANO6 ANO3

8.00e-055592GO:0061588
GeneOntologyBiologicalProcesscalcium activated phosphatidylcholine scrambling

ANO6 ANO3

8.00e-055592GO:0061590
GeneOntologyBiologicalProcesscalcium activated galactosylceramide scrambling

ANO6 ANO3

8.00e-055592GO:0061591
GeneOntologyBiologicalProcessdetection of temperature stimulus involved in sensory perception

TRPV1 CXCR4 ANO1

8.54e-0530593GO:0050961
GeneOntologyBiologicalProcesssensory perception of temperature stimulus

TRPV1 CXCR4 ANO1

1.75e-0438593GO:0050951
DomainAnoct_dimer

ANO6 ANO1 ANO3

9.86e-077583PF16178
DomainAnoct_dimer

ANO6 ANO1 ANO3

9.86e-077583IPR032394
DomainAnoctamin

ANO6 ANO1 ANO3

3.36e-0610583PF04547
DomainAnoctamin

ANO6 ANO1 ANO3

3.36e-0610583IPR007632
DomainMAM_1

PTPRK PTPRU PTPRT

1.55e-0516583PS00740
DomainMAM

PTPRK PTPRU PTPRT

1.87e-0517583SM00137
DomainMAM

PTPRK PTPRU PTPRT

2.24e-0518583PF00629
DomainMAM_dom

PTPRK PTPRU PTPRT

2.24e-0518583IPR000998
DomainMAM_2

PTPRK PTPRU PTPRT

2.24e-0518583PS50060
DomainFN3

CSF2RB PTPRK CNTN3 ASTN1 PTPRU PTPRT

2.30e-05185586SM00060
DomainBMP_1/tolloid-like

BMP1 TLL2

2.84e-053582IPR015446
DomainFN3

CSF2RB PTPRK CNTN3 ASTN1 PTPRU PTPRT

3.46e-05199586PS50853
DomainFN3_dom

CSF2RB PTPRK CNTN3 ASTN1 PTPRU PTPRT

4.56e-05209586IPR003961
DomainSCAMP

SCAMP4 SCAMP5

9.42e-055582IPR007273
DomainSCAMP

SCAMP4 SCAMP5

9.42e-055582PF04144
DomainPeptidase_M12A

BMP1 TLL2

1.41e-046582IPR001506
DomainAstacin

BMP1 TLL2

1.41e-046582PF01400
Domainfn3

CSF2RB PTPRK CNTN3 PTPRU PTPRT

1.46e-04162585PF00041
DomainGPCR_2_secretin-like_CS

ADGRL1 ADGRE5 CRHR1

1.59e-0434583IPR017983
DomainPTPc

PTPRK PTPRU PTPRT

1.89e-0436583SM00194
DomainTYR_PHOSPHATASE_PTP

PTPRK PTPRU PTPRT

2.40e-0439583PS50055
DomainPTPase_domain

PTPRK PTPRU PTPRT

2.79e-0441583IPR000242
DomainY_phosphatase

PTPRK PTPRU PTPRT

2.79e-0441583PF00102
DomainMBT

PHF20L1 SFMBT2

4.20e-0410582PF02820
DomainMbt

PHF20L1 SFMBT2

4.20e-0410582IPR004092
DomainG_PROTEIN_RECEP_F2_2

ADGRL1 ADGRE5 CRHR1

5.02e-0450583PS00650
Domain7tm_2

ADGRL1 ADGRE5 CRHR1

5.02e-0450583PF00002
DomainTRP_channel

TRPV1 TRPV6

5.12e-0411582IPR004729
DomainPTPc_motif

PTPRK PTPRU PTPRT

8.17e-0459583SM00404
DomainTyr_Pase_cat

PTPRK PTPRU PTPRT

8.17e-0459583IPR003595
DomainGPCR_2_secretin-like

ADGRL1 ADGRE5 CRHR1

8.58e-0460583IPR000832
DomainGPCR_2-like

ADGRL1 ADGRE5 CRHR1

8.58e-0460583IPR017981
DomainG_PROTEIN_RECEP_F2_4

ADGRL1 ADGRE5 CRHR1

9.00e-0461583PS50261
DomainTyr_Pase_AS

PTPRK PTPRU PTPRT

1.52e-0373583IPR016130
DomainMetalloPept_cat_dom

BMP1 TLL2 PAPPA

2.04e-0381583IPR024079
Domain-

BMP1 TLL2 PAPPA

2.04e-03815833.40.390.10
DomainTUDOR

PHF20L1 TDRD9

2.30e-0323582PS50304
DomainTYR_PHOSPHATASE_1

PTPRK PTPRU PTPRT

2.42e-0386583PS00383
DomainEGF_CA

BMP1 TLL2 ADGRE5

2.42e-0386583PF07645
DomainTYR_PHOSPHATASE_2

PTPRK PTPRU PTPRT

2.50e-0387583PS50056
DomainTYR_PHOSPHATASE_dom

PTPRK PTPRU PTPRT

2.50e-0387583IPR000387
DomainHormR

ADGRL1 CRHR1

2.72e-0325582SM00008
Domain-

PTPRK PTPRU PTPRT

2.93e-03925833.90.190.10
DomainGalactose-bd-like

PTPRK CUL9 PTPRU

3.12e-0394583IPR008979
DomainTUDOR

PHF20L1 TDRD9

3.16e-0327582SM00333
DomainHRM

ADGRL1 CRHR1

3.40e-0328582PF02793
DomainEGF_Ca-bd_CS

BMP1 TLL2 ADGRE5

3.41e-0397583IPR018097
DomainZINC_PROTEASE

BMP1 TLL2 PAPPA

3.51e-0398583PS00142
DomainProt-tyrosine_phosphatase-like

PTPRK PTPRU PTPRT

3.61e-0399583IPR029021
DomainEGF_CA

BMP1 TLL2 ADGRE5

3.61e-0399583PS01187
DomainZnMc

BMP1 TLL2

3.65e-0329582SM00235
DomainPeptidase_Metallo

BMP1 TLL2

3.65e-0329582IPR006026
DomainTudor

PHF20L1 TDRD9

3.90e-0330582IPR002999
DomainEGF-type_Asp/Asn_hydroxyl_site

BMP1 TLL2 ADGRE5

4.37e-03106583IPR000152
DomainConA-like_dom

PTPRK PAPPA PTPRU PTPRT

4.76e-03219584IPR013320
DomainGPS

ADGRL1 ADGRE5

4.99e-0334582SM00303
DomainGPS

ADGRL1 ADGRE5

5.28e-0335582PF01825
PathwayREACTOME_INDUCTION_OF_CELL_CELL_FUSION

ANO6 ANO1 ANO3

1.03e-0513483M46426
PathwayREACTOME_STIMULI_SENSING_CHANNELS

TRPV1 ANO6 ANO1 TRPV6 ANO3

2.08e-0599485MM14910
PathwayREACTOME_ION_CHANNEL_TRANSPORT

ATP8B3 TRPV1 ANO6 ANO1 TRPV6 ANO3

2.76e-05176486MM15718
PathwayREACTOME_STIMULI_SENSING_CHANNELS

TRPV1 ANO6 ANO1 TRPV6 ANO3

2.89e-05106485M27200
PathwayREACTOME_ION_CHANNEL_TRANSPORT

ATP8B3 TRPV1 ANO6 ANO1 TRPV6 ANO3

3.44e-05183486M997
PathwayWP_GPCRS_CLASS_B_SECRETINLIKE

ADGRL1 ADGRE5 CRHR1

7.13e-0524483M39643
PathwayWP_GPCRS_CLASS_B_SECRETINLIKE

ADGRL1 ADGRE5 CRHR1

7.13e-0524483MM15992
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

BMP1 TLL2 CTSL

6.49e-0450483MM14796
Pubmed

Expression patterns of the Tmem16 gene family during cephalic development in the mouse.

ANO6 ANO1 ANO3

9.73e-08660319059364
Pubmed

Identification and characterization of TMEM16E and TMEM16F genes in silico.

ANO6 ANO1 ANO3

9.73e-08660315067359
Pubmed

The anoctamin family: TMEM16A and TMEM16B as calcium-activated chloride channels.

ANO6 ANO1 ANO3

2.72e-07860321984732
Pubmed

Expression of TMEM16 paralogs during murine embryogenesis.

ANO6 ANO1 ANO3

2.72e-07860318729231
Pubmed

Calcium-dependent phospholipid scramblase activity of TMEM16 protein family members.

ANO6 ANO1 ANO3

5.81e-071060323532839
Pubmed

Anoctamin/TMEM16 family members are Ca2+-activated Cl- channels.

ANO6 ANO1 ANO3

5.81e-071060319015192
Pubmed

Structure and function of TMEM16 proteins (anoctamins).

ANO6 ANO1 ANO3

5.81e-071060324692353
Pubmed

The role of TMEM16A (ANO1) and TMEM16F (ANO6) in cell migration.

ANO6 ANO1

2.93e-06260223832500
Pubmed

Niclosamide repurposed for the treatment of inflammatory airway disease.

ANO6 ANO1

2.93e-06260231391337
Pubmed

Defining the binding interface of Amyloid Precursor Protein (APP) and Contactin3 (CNTN3) by site-directed mutagenesis.

CNTN3 APP

2.93e-06260231318883
Pubmed

Functional swapping between transmembrane proteins TMEM16A and TMEM16F.

ANO6 ANO1

2.93e-06260224478309
Pubmed

Pain-enhancing mechanism through interaction between TRPV1 and anoctamin 1 in sensory neurons.

TRPV1 ANO1

2.93e-06260225848051
Pubmed

Plasma membrane-localized TMEM16 proteins are indispensable for expression of CFTR.

ANO6 ANO1

8.77e-06360230915480
Pubmed

Structural basis for the substrate specificity of bone morphogenetic protein 1/tolloid-like metalloproteases.

BMP1 TLL2

8.77e-06360218824173
Pubmed

Putative pore-loops of TMEM16/anoctamin channels affect channel density in cell membranes.

ANO6 ANO1

8.77e-06360223613533
Pubmed

Genetic analysis of the role of proteolysis in the activation of latent myostatin.

BMP1 TLL2

8.77e-06360218286185
Pubmed

Identification of a dimerization domain in the TMEM16A calcium-activated chloride channel (CaCC).

ANO6 ANO1

8.77e-06360223576756
Pubmed

A molecular determinant of phosphoinositide affinity in mammalian TRPV channels.

TRPV1 TRPV6

8.77e-06360227291418
Pubmed

Anoctamins support calcium-dependent chloride secretion by facilitating calcium signaling in adult mouse intestine.

ANO6 ANO1

8.77e-06360224974903
Pubmed

The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons.

TRPV1 ANO1

8.77e-06360222634729
Pubmed

A genome-wide association study in Han Chinese identifies new susceptibility loci for ankylosing spondylitis.

CSF2RB ANO6

1.75e-05460222138694
Pubmed

Differential expression of MAM-subfamily protein tyrosine phosphatases during mouse development.

PTPRK PTPRU

1.75e-0546029510027
Pubmed

A region encompassing the FERM domain of Jak1 is necessary for binding to the cytokine receptor gp130.

JAK3 CSF2RB

1.75e-05460211557047
Pubmed

FLJ10261 gene, located within the CCND1-EMS1 locus on human chromosome 11q13, encodes the eight-transmembrane protein homologous to C12orf3, C11orf25 and FLJ34272 gene products.

ANO1 ANO3

1.75e-05460212739008
Pubmed

HIV envelope protein gp120-induced apoptosis in lung microvascular endothelial cells by concerted upregulation of EMAP II and its receptor, CXCR3.

CXCR4 EML2

1.75e-05460224318111
Pubmed

Fe65 is required for Tip60-directed histone H4 acetylation at DNA strand breaks.

APP TRRAP

1.75e-05460219282473
Pubmed

Molecular cloning of cDNAs encoding a LD78 receptor and putative leukocyte chemotactic peptide receptors.

HCAR3 CXCR4

1.75e-0546027505609
Pubmed

Novel SCAMPs lacking NPF repeats: ubiquitous and synaptic vesicle-specific forms implicate SCAMPs in multiple membrane-trafficking functions.

SCAMP4 SCAMP5

2.92e-05560211050114
Pubmed

Interaction of amyloid precursor protein with contactins and NgCAM in the retinotectal system.

CNTN3 APP

2.92e-05560218272596
Pubmed

Central CRF system perturbation in an Alzheimer's disease knockin mouse model.

APP CRHR1

2.92e-05560222336193
Pubmed

Role and regulation of TRP channels in neutrophil granulocytes.

TRPV1 TRPV6

2.92e-05560212765698
Pubmed

Mammalian BMP-1/Tolloid-related metalloproteinases, including novel family member mammalian Tolloid-like 2, have differential enzymatic activities and distributions of expression relevant to patterning and skeletogenesis.

BMP1 TLL2

2.92e-05560210479448
Pubmed

Posttraumatic stress disorder-like induction elevates β-amyloid levels, which directly activates corticotropin-releasing factor neurons to exacerbate stress responses.

APP CRHR1

2.92e-05560225673853
Pubmed

Elevated ATF4 function in fibroblasts and liver of slow-aging mutant mice.

PAPPA TRPV6

4.37e-05660224691093
Pubmed

ANOs 3-7 in the anoctamin/Tmem16 Cl- channel family are intracellular proteins.

ANO6 ANO1

6.11e-05760222075693
Pubmed

Metabolic rewiring tunes dermal macrophages in staphylococcal skin infection.

CSF2RB CXCR4

8.14e-05860237566679
Pubmed

Expression and function of epithelial anoctamins.

ANO6 ANO1

8.14e-05860220056604
Pubmed

Anoctamins are a family of Ca2+-activated Cl- channels.

ANO6 ANO1

8.14e-05860222946059
Pubmed

The chemokine SDF-1alpha triggers CXCR4 receptor dimerization and activates the JAK/STAT pathway.

JAK3 CXCR4

1.05e-04960210506573
Pubmed

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.

PTPRK CNTN3 PTPRU PTPRT

1.81e-0416260425826454
Pubmed

Depletion of mammalian CCR4b deadenylase triggers elevation of the p27Kip1 mRNA level and impairs cell growth.

CHAF1A CNOT2

1.91e-041260217452450
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

SEL1L BMP1 PTPRK CXCR4 ANO6 DHCR7 ADGRE5 APP CTSL

2.05e-04120160935696571
Pubmed

Differential gene expression in migrating cortical interneurons during mouse forebrain development.

ASTN1 PTPRT

2.26e-041360220151419
Pubmed

Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells.

BPTF SEC23IP EML2 SFMBT2

2.53e-0417760426206133
Pubmed

Restored expression of major histocompatibility class I molecules by gene transfer of a putative peptide transporter.

PAPPA CTSL

2.63e-04146022034277
Pubmed

Construction and characterization of human brain cDNA libraries suitable for analysis of cDNA clones encoding relatively large proteins.

ASTN1 PTPRT

2.63e-04146029179496
Pubmed

Chromatin boundaries require functional collaboration between the hSET1 and NURF complexes.

BPTF TRRAP

3.91e-041760221653943
Pubmed

Expression profile analysis of vulnerable CA1 pyramidal neurons in young-Middle-Aged Ts65Dn mice.

BMP1 BPTF APP

4.36e-048560325131634
Pubmed

Deficiency of TRPM2 leads to embryonic neurogenesis defects in hyperthermia.

TRPV1 ANO1

4.40e-041860231911949
Pubmed

USF1 recruits histone modification complexes and is critical for maintenance of a chromatin barrier.

BPTF TRRAP

4.40e-041860217846119
Pubmed

CUEDC2, a novel interacting partner of the SOCS1 protein, plays important roles in the leukaemogenesis of acute myeloid leukaemia.

JAK3 CSF2RB CXCR4

4.67e-048760329991678
Pubmed

Genomewide discovery and classification of candidate ovarian fertility genes in the mouse.

TDRD9 EMILIN3

4.91e-041960217660561
Pubmed

Mapping the expression of transient receptor potential channels across murine placental development.

TRPV1 TRPV6

7.88e-042460233884443
Pubmed

Munc18-1 stabilizes syntaxin 1, but is not essential for syntaxin 1 targeting and SNARE complex formation.

SCAMP4 SCAMP5

8.56e-042560215935055
Pubmed

International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels.

TRPV1 TRPV6

8.56e-042560216382100
Pubmed

Gse1, a component of the CoREST complex, is required for placenta development in the mouse.

CLEC2L CTSL

8.56e-042560237019373
Pubmed

Aberrant differentiation of second heart field mesoderm prefigures cellular defects in the outflow tract in response to loss of FGF8.

CLEC2L CTSL

9.26e-042660237060937
Pubmed

Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defects.

BMP1 CXCR4

9.99e-042760224586749
Pubmed

An introduction to TRP channels.

TRPV1 TRPV6

9.99e-042760216460286
Pubmed

NANOG-dependent function of TET1 and TET2 in establishment of pluripotency.

BPTF TRRAP

9.99e-042760223395962
Pubmed

Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.

WDR7 CXCR4 SEC23IP APP

1.15e-0326560419240061
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

SEL1L SCAMP4 PTPRK GLE1 DHCR7 SEC23IP APP

1.16e-0394260731073040
Pubmed

ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.

MRPS30 SCAMP4 WDR7 ANO6 DHCR7 SEC23IP APP

1.23e-0395260738569033
Pubmed

Proliferative activity of extracellular HIV-1 Tat protein in human epithelial cells: expression profile of pathogenetically relevant genes.

BMP1 CXCR4

1.23e-033060215857508
Pubmed

Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers.

BPTF CHAF1A TRRAP

1.31e-0312460320850016
Pubmed

Dissection of behavior and psychiatric disorders using the mouse as a model.

APP CRHR1

1.32e-033160210767319
Pubmed

Sf3b4 regulates chromatin remodeler splicing and Hox expression.

PHF20L1 HOXD11

1.40e-033260237167859
Pubmed

International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.

ADGRL1 ADGRE5

1.49e-033360225713288
Pubmed

A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.

TRPV1 TRPV6

1.49e-033360219834762
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

PTPRK KLHL7 SEC23IP CUL9 ASTN1 APP CTSL CNOT2

1.58e-03128560835914814
InteractionTTLL6 interactions

CUL9 APP TRRAP

6.34e-0613583int:TTLL6
CytobandEnsembl 112 genes in cytogenetic band chr19p13

JAK3 ATP8B3 SCAMP4 CHAF1A ADGRL1 ADGRE5 NMRK2

8.04e-05797607chr19p13
Cytoband19p13.3

ATP8B3 SCAMP4 CHAF1A NMRK2

2.69e-0423760419p13.3
Cytoband7q34

TRBV12-4 CLEC2L TRPV6

1.39e-031676037q34
CytobandEnsembl 112 genes in cytogenetic band chr7q34

TRBV12-4 CLEC2L TRPV6

1.86e-03185603chr7q34
GeneFamilyAnoctamins

ANO6 ANO1 ANO3

2.08e-0610483865
GeneFamilyFibronectin type III domain containing

CSF2RB PTPRK CNTN3 ASTN1 PTPRU PTPRT

3.95e-06160486555
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRK PTPRU PTPRT

2.26e-0521483813
GeneFamilySecretory carrier membrane proteins

SCAMP4 SCAMP5

6.87e-055482735
GeneFamilyBone morphogenetic proteins|Astacins

BMP1 TLL2

1.03e-046482894
GeneFamilyTransient receptor potential cation channels

TRPV1 TRPV6

2.50e-0328482249
GeneFamilyTudor domain containing

PHF20L1 TDRD9

4.33e-0337482780
GeneFamilyImmunoglobulin like domain containing

PTPRK CNTN3 PTPRT

1.46e-02193483594
ToppCellTracheal-10x5prime-Immune_Myeloid-Dendritic_cell-DC_plasmacytoid|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

JAK3 CSF2RB SCAMP5 CXCR4 CHAF1A

3.16e-06168605c34dd4a9c54d8e9c8f118e6a3816548890cb0746
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTPRK OTOGL CNTN3 ANO3 PTPRT

3.35e-061706053174ea9cf93892a8b41de10fd4ff6f06bb41502d
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTPRK OTOGL CNTN3 ANO3 PTPRT

4.20e-061786050e1bedf991189d0ef9b40dac9281bdf4739333a1
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-pDC|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CSF2RB SCAMP5 CHAF1A ADGRL1 APP

4.68e-0618260502c0824373a0ecebc922d4ca848ace9d570722c4
ToppCellILEUM-inflamed-(3)_MNP-(3)_pDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CSF2RB SCAMP5 CXCR4 CHAF1A APP

5.06e-06185605308a98f111895071d8772bc010554471cc12fab2
ToppCelltumor_Lung-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

CSF2RB SCAMP5 CXCR4 CHAF1A APP

5.20e-061866053d7c1a281fb82db4471283f39937007d889a5f38
ToppCellcellseq-Immune-Immune_Myeloid-Myeloid_Dendritic-pDC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TCL1B CSF2RB SCAMP5 CXCR4 CHAF1A

5.20e-06186605d23c3318937492d7d665bec14253124c49181b5a
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TCL1B CSF2RB SCAMP5 CXCR4 CHAF1A

5.47e-061886051f820cb19eb0e15f0eb69d07e457072bbdad8ecb
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TCL1B CSF2RB SCAMP5 CXCR4 CHAF1A

5.76e-06190605c44aae2e0d3cc84a187e12917fd8c2d7483f41d8
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TCL1B CSF2RB SCAMP5 CXCR4 CHAF1A

5.76e-06190605705489ebbaf3d8e643498c3e507742114475fc55
ToppCellproximal-Hematologic-Plasmacytoid_Dendritic|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TCL1B CSF2RB SCAMP5 CXCR4 CHAF1A

6.06e-06192605faead5875a54fe8f1848ae36008aae4c0f7cb1c7
ToppCellproximal-3-Hematologic-Plasmacytoid_Dendritic|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TCL1B CSF2RB SCAMP5 CXCR4 CHAF1A

6.06e-0619260586938c7d2bb1a7afb2b83828ca33dd137d366ec6
ToppCellproximal-Hematologic-Plasmacytoid_Dendritic-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TCL1B CSF2RB SCAMP5 CXCR4 CHAF1A

6.06e-06192605e3be395a995dc8c0ebdae754057cfa59a270cae0
ToppCelldistal-Hematologic-Plasmacytoid_Dendritic-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TCL1B CSF2RB SCAMP5 CXCR4 SFMBT2

6.70e-06196605170629b9ae82e9a911b93e8739dcd38176fbecb4
ToppCellParenchymal-10x5prime-Immune_Myeloid-Dendritic_cell-DC_plasmacytoid|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CSF2RB SCAMP5 CXCR4 CHAF1A APP

6.70e-06196605b10b386aacc672949560df2dbb0d4f76cf62e213
ToppCellTracheal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_activated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

JAK3 ATP8B3 CXCR4 CHAF1A HELZ2

7.22e-061996056dc446a5d183b01bdf227e45bd88d0b3d8b1c56a
ToppCellNeuronal-Excitatory-eC(RORB)-eC_1-TWIST2-|Neuronal / cells hierarchy compared to all cells using T-Statistic

PTPRK HOXD11 OTOGL ANO3 PTPRT

7.39e-06200605af5d4a3d735f38c6e07b5d7bd2965b0486632c4e
ToppCellNeuronal-Excitatory-eC(RORB)-eC_1-TWIST2|Neuronal / cells hierarchy compared to all cells using T-Statistic

PTPRK HOXD11 OTOGL ANO3 PTPRT

7.39e-06200605bbfbefd24cc070b010e787e08ff6bff4a7ee3f7c
ToppCellNeuronal-Excitatory-eC(RORB)-eC_1-TWIST2--L3-5|Neuronal / cells hierarchy compared to all cells using T-Statistic

PTPRK HOXD11 OTOGL ANO3 PTPRT

7.39e-06200605b9ef0e11c8e22f2c9c926fd48fa2005ef8d22752
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM178A DHCR7 PAPPA TRPV6

3.93e-051416049a0f4bee2893da1b13ab89494e6159821d53538b
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Thalamus / BrainAtlas - Mouse McCarroll V32

SGCZ SFMBT2 CRHR1 PTPRT

4.75e-05148604afebb64365c94b9476494bffe7c364677f19c8cf
ToppCellThalamus-Neuronal-Inhibitory|Thalamus / BrainAtlas - Mouse McCarroll V32

SGCZ SFMBT2 CRHR1 PTPRT

4.75e-051486045f82e5ecacfd223020b8ee975c17d68c1fe6db38
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

JAK3 SGCZ CXCR4 TRPV6

5.69e-0515560451f6447945389649d99dcf7603b396195c631ead
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic-Mast_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

JAK3 SGCZ CXCR4 TRPV6

5.69e-0515560423dc71cab28094ca0ac4d2baf4e24871ed107781
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGCZ CNTN3 ASTN1 PTPRT

6.43e-05160604c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGCZ CNTN3 ASTN1 PTPRT

6.43e-0516060425c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD4-Tfh|GI_large-bowel / Manually curated celltypes from each tissue

TRPV1 TRBV12-4 CXCR4 TRRAP

6.91e-051636044104d3b9748b39cb0744c9be76db21bdda566a0d
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_3|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

EMILIN3 PTGES3L CTSL ANO3

7.08e-05164604583dda853cee9491dbdcb228c23d8deadc20eb08
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HCAR3 CSF2RB CXCR4 ADGRE5

7.08e-051646042c929996a19bbe29949010928001c277b5494a42
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-1|TCGA-Ovary / Sample_Type by Project: Shred V9

KLHL7 TMEM178A TLL2 EMILIN3

7.25e-051656042ca1154a8692af311d99a4d3aa2f2ac3d23a4310
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

BMP1 PTPRK ANO3 CRHR1

7.59e-05167604f1ce6e64ebede1f3ef36fe982f46919fd1f814dd
ToppCellNS-moderate-d_07-13-Myeloid-pDC|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CSF2RB SCAMP5 CXCR4 CHAF1A

7.77e-05168604d03e91f0e0518b33555c0ec98124fc5ed0f11be5
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-stromal_related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SGCZ ANO1 PTGES3L CTSL

7.77e-05168604e40a3f85be7e9bb23bfbc1f9cb5e5fc54bb43863
ToppCell10x5'-lymph-node_spleen-Myeloid_Dendritic-pDC|lymph-node_spleen / Manually curated celltypes from each tissue

CSF2RB SCAMP5 CHAF1A APP

7.77e-05168604cfed36fece51871a5abbcde71f6bd5e7212357ff
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SGCZ ANO1 PTGES3L CTSL

7.77e-05168604b1d6c35a5ae69c8638afd68c2be5bc9ce6fd2659
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTPRK OTOGL ANO3 PTPRT

7.95e-05169604319cba07263bf41fcbcbfecd117f91b729394241
ToppCellfacs-Lung-24m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l14|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CSF2RB WDR7 CXCR4 SEC23IP

7.95e-05169604813472d429c0b12580b17b440e00a6d8beb7947f
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SCAMP5 CXCR4 CHAF1A PTGES3L

8.13e-05170604b49f7c8a27078de2137ed04f74cfee30729cfa5e
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTPRK OTOGL ANO3 PTPRT

8.13e-051706045de2f7d16a05af74ebfb1ca42d0f9c3c3524692d
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SGCZ OTOGL ANO1 PAPPA

8.13e-051706045570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

OTOGL CNTN3 ANO3 PTPRT

8.32e-05171604f648789e6aefe508bb748401bf9b3cd830fb0ddf
ToppCellmetastatic_Lymph_Node-Myeloid_cells-pDCs|metastatic_Lymph_Node / Location, Cell class and cell subclass

CSF2RB SCAMP5 CHAF1A APP

8.32e-051716041f8e66073088fc1969782e443bf00f8c1877ea91
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Neutrophil|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HCAR3 CSF2RB CXCR4 ADGRE5

8.32e-05171604ef9397cec7f5c217d34583f26270af7ed7fbcebf
ToppCellCOVID-pDC|COVID / Condition, Cell_class and T cell subcluster

TCL1B SCAMP5 PTGES3L APP

8.51e-051726043ecbb000495dde32f6153ef6bdea9c8802ff3985
ToppCellCOVID-pDC-|COVID / Condition, Cell_class and T cell subcluster

TCL1B SCAMP5 PTGES3L APP

8.51e-05172604a7827faa1afab51fdaf0cb1a2babcd2e00d411e5
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTPRK OTOGL ANO3 PTPRT

8.70e-051736048335b77f730ed43fc348a005566e73a103c6774b
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTPRK OTOGL ANO3 PTPRT

8.70e-051736049a2d42f8d9cb834856522661d524abb91c4637c5
ToppCellfacs-Heart-LV-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANO1 RHBDL1 ASTN1 PTGES3L

8.90e-05174604197686570cec6d96a92e77e6409325d3bfe6f991
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTPRK OTOGL ANO3 PTPRT

8.90e-05174604b3cd22e717d178269e6d5bd5ed7b2d945cd8ea25
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTPRK OTOGL ANO3 PTPRT

8.90e-05174604ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCellfacs-Heart-LV-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANO1 RHBDL1 ASTN1 PTGES3L

8.90e-051746042eee7b5471672b439f95eba11494c2adf8cb7006
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTPRK OTOGL ANO3 PTPRT

9.30e-0517660440993c41c1017b53039a337174fc56632b278609
ToppCellILEUM-inflamed-(3)_pDC|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CSF2RB SCAMP5 CHAF1A APP

9.30e-05176604b9f847dd55703e413f3cd815eef5724fffaf13b3
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CSF2RB SCAMP5 CXCR4 CHAF1A

9.51e-051776048887ff6341eb070bdaa890cc2cd7745f0cf1b0af
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CSF2RB SCAMP5 CXCR4 CHAF1A

9.51e-05177604507f06d31ab773099c9431b6f433899dc97b5566
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTPRK OTOGL ANO3 PTPRT

9.93e-051796048766a5a066091879f521acfc612abf563ff78808
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CSF2RB SCAMP5 CXCR4 CHAF1A

9.93e-05179604c9f45cfea0ceb0cdc31bcfd123aeab69aeb35c35
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid-pDC|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CSF2RB SCAMP5 CXCR4 CHAF1A

9.93e-05179604bbd4f8e988ef3f343aaedbc992b70f2bb6aff5f6
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-8|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ASB17 TCL1B PTPRK CXCR4

1.04e-04181604ca34d83daca10c5fa52ecdf4eba7d31b4e7e056e
ToppCelltumor_Lung-Myeloid_cells-pDCs|tumor_Lung / Location, Cell class and cell subclass

CSF2RB SCAMP5 CHAF1A APP

1.04e-04181604c864ffeb9234b8c29754afc91c85a972889617f4
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTPRK OTOGL CNTN3 ANO3

1.06e-0418260414a117c5e50db31ee1b2cf4df4d133451fd6d55f
ToppCellnormal_Lung-B_lymphocytes-GrB-secreting_B_cells|normal_Lung / Location, Cell class and cell subclass

CSF2RB SCAMP5 CHAF1A APP

1.08e-04183604c930b957d16f9b0904b6c424acd914532e5cc137
ToppCell(7)_DC_plasmacytoid|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

CSF2RB SCAMP5 CHAF1A APP

1.08e-041836042c6475c935b5a90931be6b3c53f1f707cfcd11f4
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP8B3 ANO1 PAPPA APP

1.08e-04183604ebe369dc80c4fbf8f4dbe947147f8c47507ffb60
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CSF2RB SCAMP5 CHAF1A APP

1.15e-041866040096a61b1841784c913752b4f3639200446cc02c
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CSF2RB SCAMP5 CHAF1A APP

1.15e-041866046345777847960c71a2ba3ce5a49c72c34ebd0e73
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTPRK OTOGL CNTN3 ANO3

1.15e-04186604bdbe290f81106a53c8c30a92fbb385597c62b2ac
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CSF2RB SCAMP5 CHAF1A APP

1.15e-041866049e159ad7289dcae2ec7ce655df746f46801b81d3
ToppCellCF-Lymphoid-pDC|Lymphoid / Disease state, Lineage and Cell class

CSF2RB SCAMP5 CHAF1A APP

1.17e-04187604adc79e5804ab98006dbdf1d76ef0d8f85cc5cb0f
ToppCellLAM-Lymphoid-pDC|Lymphoid / Condition, Lineage and Cell class

CSF2RB SCAMP5 CHAF1A APP

1.17e-041876044d9ffd2bbdf1c9869e28991ce9331e4ccf3c0166
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TLL2 PAPPA SFMBT2 PTPRT

1.22e-0418960406c44746fa4f02e6e2b3b635cdf2d8dfef3754d3
ToppCellcontrol-Myeloid-Neutrophils_1|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

HCAR3 CSF2RB CXCR4 ADGRE5

1.27e-04191604db1b3cd07d7d190155b2d14e82e1d124975fbd0b
ToppCellCOVID-19_Moderate-pDC|World / disease group, cell group and cell class

CSF2RB SCAMP5 CHAF1A APP

1.27e-0419160493adfbc0b22f6006d6d5ad67a99e33cbe9e1dfe9
ToppCellBAL-Severe-Myeloid-pDC-pDC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TCL1B SCAMP5 CHAF1A APP

1.27e-04191604989bf108c7f2c78dd7f14481570f1819673a5469
ToppCell15-Trachea-Epithelial-Submucosal_gland_basal|Trachea / Age, Tissue, Lineage and Cell class

CXCR4 CHDH ANO1 PAPPA

1.27e-04191604409e12d2bb26b6d2ed025304ca6ace07df16638a
ToppCellBAL-Severe-Myeloid-pDC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TCL1B SCAMP5 CHAF1A APP

1.27e-041916043e7fbe4af2c23b3b964becde843d2f088ad41c23
ToppCellBAL-Severe-Myeloid-pDC-pDC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TCL1B SCAMP5 CHAF1A APP

1.27e-04191604bc2f3c4e71e3a55fe76ea03f45746329a8fc81da
ToppCellBAL-Severe-Myeloid-pDC-pDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

TCL1B SCAMP5 CHAF1A APP

1.30e-04192604d9ff2293358c8b031ba212021012e058014ff472
ToppCellCOVID-19-kidney-Myeloid|kidney / Disease (COVID-19 only), tissue and cell type

HCAR3 CSF2RB CXCR4 ADGRE5

1.30e-04192604441cd1ec171f643b28e1f6f9c04def629cc7391b
ToppCellSevere_COVID-19-Myeloid-pDC|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

TCL1B SCAMP5 CHAF1A APP

1.30e-04192604f79424c643a375dfe4579eff7ac1ba191e28a283
ToppCellBAL-Severe-Myeloid-pDC-pDC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TCL1B SCAMP5 CHAF1A APP

1.30e-041926042e8611d65090e39f1a6e74c972288e7b68376d15
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANO1 ADGRL1 ASTN1 PTGES3L

1.30e-04192604eb9a0b3d32f90f8b95905c740aab21639dae5cbd
ToppCellBAL-Severe-Myeloid-pDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

TCL1B SCAMP5 CHAF1A APP

1.30e-0419260443569726df281eebe57499e0993b9fd9d36118c2
ToppCellCOVID-19-kidney-Myeloid|COVID-19 / Disease (COVID-19 only), tissue and cell type

HCAR3 CSF2RB CXCR4 ADGRE5

1.30e-041926040b9d22a222f1201e375f8e55cace9ef939febae4
ToppCellmedial-Hematologic-Plasmacytoid_Dendritic|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CSF2RB SCAMP5 CXCR4 CHAF1A

1.35e-04194604bb36274d6fe2d18c545a17d3809f331586502d01
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC3|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TCL1B CSF2RB SCAMP5 CHAF1A

1.35e-041946043f9e4a8e5699bc379e8a0d337e0daef09632e71c
ToppCellRA|World / Chamber and Cluster_Paper

OTOGL PAPPA NMRK2 ANO3

1.35e-0419460408f0afbb68a63150fbe107a5337299081c3f69e4
ToppCellmedial-2-Hematologic-Plasmacytoid_Dendritic|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CSF2RB SCAMP5 CXCR4 CHAF1A

1.35e-04194604d58be6454a0795d6771036a1620553a153861615
ToppCellmedial-Hematologic-Plasmacytoid_Dendritic-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CSF2RB SCAMP5 CXCR4 CHAF1A

1.35e-041946040117cd68750153fd6b8978c8b4ce3589486d2b5f
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC3-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TCL1B CSF2RB SCAMP5 CHAF1A

1.35e-041946045250736b608001fb73aa74dee8cb8465a1d2f372
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP1 SGCZ WDR7 ADGRL1

1.38e-04195604bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GJA3 CSF2RB SCAMP5 SFMBT2

1.38e-04195604bb30ac112f8c42d113fa83a9b662e40c0685bb1e
ToppCellbackground-Endothelial_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

APP CTSL SFMBT2 PTPRT

1.41e-04196604e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-41|World / Primary Cells by Cluster

TDRD9 CXCR4 APP CNOT2

1.41e-04196604dee0984cd63a1a2fdebb4421af48ab566a5b684e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HOXD11 ANO1 ADGRE5 ANO3

1.41e-04196604fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HOXD11 ANO1 ADGRE5 ANO3

1.41e-04196604802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCellBiopsy_IPF-Immune-pDCs|Biopsy_IPF / Sample group, Lineage and Cell type

CSF2RB SCAMP5 CXCR4 CHAF1A

1.46e-04198604aa8943e6796f619406056cf763b751fe9a9a3e0c
ToppCell(5)_Dendritic_cell-(54)_pDC|(5)_Dendritic_cell / shred on Cell_type and subtype

CSF2RB SCAMP5 CXCR4 APP

1.46e-04198604fc6c6b60dddd7f2f997af0f87fae33f1c23f34a8
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4_TRM/EMRA|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CXCR4 ADGRE5 NMRK2 SFMBT2

1.46e-04198604cf2057fc7c41d509ff76c0f1916e801a2a8406b2
ToppCelldistal-mesenchymal-Myofibroblast-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TDRD9 ANO1 PAPPA ANO3

1.46e-04198604beef5075ba6dcd4d0a447bc4e57efcaf2e93c546
Drugpromethium

BMP1 CSF2RB CNTN3

2.69e-0611593CID000023944
DrugT16AInh-A01

ANO6 ANO1

6.60e-062592ctd:C578466
Drugdigallic acid

ANO6 ANO1

6.60e-062592ctd:C067648
DrugButylparaben [94-26-8]; Up 200; 20.6uM; HL60; HT_HG-U133A

SEL1L BMP1 CUL9 ADGRL1 PAPPA CRHR1

1.20e-051975963069_UP
Drugczp

GJA3 TRPV1 ADGRE5

1.31e-0518593CID005288014
DiseaseAutistic Disorder

HOXD11 SCAMP5 DHCR7 CNTN3 TRRAP

1.77e-04261595C0004352
DiseaseT-cell acute lymphoblastic leukemia (is_implicated_in)

JAK3 CXCR4

2.14e-0411592DOID:5603 (is_implicated_in)
Diseasesensory peripheral neuropathy, remission

SGCZ PTPRT

9.68e-0423592EFO_0009785, MONDO_0002321
Diseasemajor depressive disorder, COVID-19

CRHR1 PTPRT

1.24e-0326592MONDO_0002009, MONDO_0100096
Diseaseattention deficit hyperactivity disorder (implicated_via_orthology)

ADGRL1 ADGRE5

1.44e-0328592DOID:1094 (implicated_via_orthology)
DiseaseIntellectual Disability

BPTF SCAMP5 DHCR7 ASTN1 TRRAP

1.99e-03447595C3714756

Protein segments in the cluster

PeptideGeneStartEntry
DDRYICDRFYPNDLW

CXCR4

181

P61073
RWYFDVTEGKCAPFF

APP

306

P05067
YRSYGTEKACWLRVD

ADGRL1

986

O94910
KGYGRPRYCWLDFEQ

ADGRE5

676

P48960
SSDKGRLCYYRDWLL

GLE1

16

Q53GS7
GRWSYVRICKFLRYF

ATP8B3

986

O60423
SVYEKRPDFRMCWYV

CHAF1A

806

Q13111
CASKYGRDWERYTAA

DHCR7

451

Q9UBM7
YPDDYRPSKVCIWRI

BMP1

451

P13497
WPEVLRVYCESDKEY

BPTF

326

Q12830
CRYSEIKPYGLDWAE

ASTN1

1261

O14525
RGWDYAHCLPYFRKA

CHDH

156

Q8NE62
KSGYCRYRDYRGPPW

ANO3

881

Q9BYT9
RIRFYFPNWFGLEKC

JAK3

101

P52333
GDPVYWLGKYRNEEC

ANO6

581

Q4KMQ2
WFDYIPSTRYKDPCE

ASB17

241

Q8WXJ9
CRYFNPKDYSWTDIR

KLHL7

306

Q8IXQ5
ICRYKDYREPPWSEN

ANO1

861

Q5XXA6
YDKCSYISRDRGWVV

PAPPA

141

Q13219
KCVRYWPDDTEVYGD

PTPRT

996

O14522
VKCSRYWPEDSDTYG

PTPRU

996

Q92729
TVKELCRRWYPEEYE

REXO2

171

Q9Y3B8
CRRWYPEEYEFAPKK

REXO2

176

Q9Y3B8
RFCGIYGYRLRRKWE

CSF2RB

461

P32927
VAFRDYGLERAKWPY

HOXD11

61

P31277
KCWFGKRPGVYTDYI

CRHR1

286

P34998
AWRAPDFVPRYCKLY

CUL9

1491

Q8IWT3
KLEWVYGYRGRDCRA

EML2

56

O95834
ESYVKAEYRQCRWGP

EMILIN3

76

Q9NT22
YGFELKPLYRCDRWP

GJA3

171

Q9Y6H8
PRDRYRDVDEYACVW

HELZ2

1931

Q9BYK8
YVCWFRPVYKAFRAD

SCAMP4

86

Q969E2
YVCWFRPIYKAFKTD

SCAMP5

86

Q8TAC9
ERFRYGWCKSYRPVS

PROCA1

141

Q8NCQ7
YWECRASGKPKPSYR

CNTN3

336

Q9P232
VPYRKMCEWRYEPCA

OTOGL

1366

Q3ZCN5
GRVKCYKYWPDDTEV

PTPRK

991

Q15262
CYGYFRKLRNWSDAE

REG4

41

Q9BYZ8
RWTDCRYYPAKIEAI

PHF20L1

96

A8MW92
CRDPPGQRWSAKYRY

PHF20L1

726

A8MW92
RRYFLTVPYEECKWR

NMRK2

116

Q9NPI5
DYRCPVHFYWVRGEE

MRPS30

201

Q9NP92
REDGRLWCATTYDYK

SEL1L

146

Q9UBV2
SRGYCYRLVHKDFWD

TDRD9

501

Q8NDG6
YSGLWRKCYFLGIDR

TMEM178A

111

Q8NBL3
YYVRRSDWKFGDIPC

HCAR3

86

P49019
VGIYGWRKRCLYFFV

SGCZ

26

Q96LD1
EPAEVRRCTWFYKGD

SEC23IP

336

Q9Y6Y8
EILPCEVDRRWYFYR

RHBDL1

176

O75783
FYEAPRSVDWREKGY

CTSL

111

P07711
PEDWLLYGRKCYFFS

CLEC2L

101

P0C7M8
RGTYYFFDCLNWRKV

CNOT2

496

Q9NZN8
KEKPVCRRRYYEEGW

TULP4

31

Q9NRJ4
YTPDGKDDYRWCFRV

TRPV1

731

Q8NER1
LRYCGYGEDRRADFW

SFMBT2

106

Q5VUG0
YDYVEVRDGYWRKAP

TLL2

406

Q9Y6L7
LVSLKWKRYGRPYFC

TRPV6

356

Q9H1D0
WKRYGRPYFCMLGAI

TRPV6

361

Q9H1D0
YPGRKYRAADSSFWE

TCL1B

91

O95988
RCKPISGHDYLFWYR

TRBV12-4

41

A0A0B4J2E0
TLWYDRPRYVFMEFC

PTGES3L

51

E9PB15
KYWRVFDAGDYSLLC

WDR7

236

Q9Y4E6
EPYYRRQAWEVIKCF

TRRAP

956

Q9Y4A5