Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	mesodermal cell fate determination	TRIM15 KLF4	4.67e-05	3	82	2	GO:0007500
GeneOntologyBiologicalProcess	positive regulation of brown fat cell differentiation	RREB1 ZBTB7B HNRNPU	4.73e-05	18	82	3	GO:0090336
Domain	-	LRP10 CDCP2 CRHBP MASP2	7.59e-05	52	81	4	2.60.120.290
Domain	CUB_dom	LRP10 CDCP2 CRHBP MASP2	1.09e-04	57	81	4	IPR000859
Domain	-	AIFM1 TXNRD2	3.85e-04	7	81	2	3.30.390.30
Domain	Pyr_nucl-diS_OxRdtase_dimer	AIFM1 TXNRD2	5.11e-04	8	81	2	IPR004099
Domain	FAD/NAD-linked_Rdtase_dimer	AIFM1 TXNRD2	5.11e-04	8	81	2	IPR016156
Domain	TRYPSIN_HIS	KLK15 CELA1 KLK1 MASP2	1.05e-03	103	81	4	IPR018114
Domain	TRYPSIN_SER	KLK15 CELA1 KLK1 MASP2	1.17e-03	106	81	4	PS00135
Domain	TIL	SSPOP MUC5AC	1.19e-03	12	81	2	PF01826
Domain	C8	SSPOP MUC5AC	1.19e-03	12	81	2	PF08742
Domain	TRYPSIN_HIS	KLK15 CELA1 KLK1 MASP2	1.21e-03	107	81	4	PS00134
Domain	CUB	LRP10 CDCP2 MASP2	1.25e-03	49	81	3	PF00431
Domain	CUB	LRP10 CDCP2 MASP2	1.33e-03	50	81	3	SM00042
Domain	Unchr_dom_Cys-rich	SSPOP MUC5AC	1.40e-03	13	81	2	IPR014853
Domain	C8	SSPOP MUC5AC	1.40e-03	13	81	2	SM00832
Domain	Peptidase_S1A	KLK15 CELA1 KLK1 MASP2	1.48e-03	113	81	4	IPR001314
Domain	CUB	LRP10 CDCP2 MASP2	1.57e-03	53	81	3	PS01180
Domain	TRYPSIN_DOM	KLK15 CELA1 KLK1 MASP2	1.58e-03	115	81	4	PS50240
Domain	TIL_dom	SSPOP MUC5AC	1.63e-03	14	81	2	IPR002919
Domain	Tryp_SPc	KLK15 CELA1 KLK1 MASP2	1.68e-03	117	81	4	SM00020
Domain	-	GPD2 AIFM1 TXNRD2	1.85e-03	56	81	3	3.50.50.60
Domain	Trypsin	KLK15 CELA1 KLK1 MASP2	1.90e-03	121	81	4	PF00089
Domain	Trypsin_dom	KLK15 CELA1 KLK1 MASP2	1.90e-03	121	81	4	IPR001254
Domain	FAD/NAD-binding_dom	GPD2 AIFM1 TXNRD2	1.94e-03	57	81	3	IPR023753
Domain	Peptidase_S1_PA	KLK15 CELA1 KLK1 MASP2	2.02e-03	123	81	4	IPR009003
Domain	VWD	SSPOP MUC5AC	2.14e-03	16	81	2	SM00216
Domain	VWF_type-D	SSPOP MUC5AC	2.14e-03	16	81	2	IPR001846
Domain	VWFD	SSPOP MUC5AC	2.14e-03	16	81	2	PS51233
Domain	VWD	SSPOP MUC5AC	2.14e-03	16	81	2	PF00094
Domain	CTCK_1	SSPOP MUC5AC	2.72e-03	18	81	2	PS01185
Domain	VWC_out	SSPOP MUC5AC	3.03e-03	19	81	2	SM00215
Domain	Pyr_redox_2	AIFM1 TXNRD2	3.03e-03	19	81	2	PF07992
Domain	ZnF_RBZ	DZANK1 TEX13A	4.43e-03	23	81	2	SM00547
Domain	Spectrin	SPTBN4 TRIO	4.43e-03	23	81	2	PF00435
Domain	Znf_RanBP2	DZANK1 TEX13A	5.22e-03	25	81	2	IPR001876
Domain	Cys_knot_C	SSPOP MUC5AC	5.22e-03	25	81	2	IPR006207
Domain	CTCK_2	SSPOP MUC5AC	5.22e-03	25	81	2	PS01225
Domain	FYVE	FGD5 RUFY1	6.99e-03	29	81	2	PF01363
Domain	FYVE	FGD5 RUFY1	6.99e-03	29	81	2	SM00064
Domain	Spectrin_repeat	SPTBN4 TRIO	6.99e-03	29	81	2	IPR002017
Domain	TRYPSIN_SER	CELA1 KLK1 MASP2	7.04e-03	90	81	3	IPR033116
Pubmed	A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.	TBX18 KRT13 TRIO ICE1 C5 AMER3 RREB1 HNRNPU	5.00e-07	284	85	8	29459677
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SPTBN4 DZANK1 UBE2O LRFN1 BCL11B TRIO ICAM5 SEC16A ZNF318 ARMCX4 WNK2 HNRNPU WDR47	6.08e-07	963	85	13	28671696
Pubmed	Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.	UBE2O GANAB ZNF318 SSPOP MUC5AC	8.88e-07	71	85	5	33541421
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	FREM2 TBC1D30 AIFM1 KRT28 MCM3AP NAGLU TSPYL6 ICE1 AMER3 SSPOP HNRNPU	1.82e-06	736	85	11	29676528
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	NHSL1 LRFN1 TRIO KIF26A TSNARE1 MCM3AP NAGLU SEC16A ICE1 TXNRD2 KLF4 WNK2 HR	2.78e-06	1105	85	13	35748872
Pubmed	Krüppel-like Factor 4 Promotes Esophageal Squamous Cell Carcinoma Differentiation by Up-regulating Keratin 13 Expression.	KRT13 KLF4	5.90e-06	2	85	2	25851906
Pubmed	Loss of non-motor kinesin KIF26A causes congenital brain malformations via dysregulated neuronal migration and axonal growth as well as apoptosis.	BCL11B KIF26A	1.77e-05	3	85	2	36228617
Pubmed	Genomic organization of the human kallikrein gene family on chromosome 19q13.3-q13.4.	KLK15 KLK1	3.53e-05	4	85	2	11006094
Pubmed	Experimentally-induced anti-myeloperoxidase vasculitis does not require properdin, MASP-2 or bone marrow-derived C5.	C5 MASP2	3.53e-05	4	85	2	27235854
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	NHSL1 UBE2O TRIO CHAF1A FGD5 ZNF318 KLF4 TARBP1 ZNF646	4.81e-05	689	85	9	36543142
Pubmed	Two-color in situ hybridization of whole-mount mouse embryos.	TBX18 UNCX	5.87e-05	5	85	2	24318811
Pubmed	Segmental expression of the T-box transcription factor, Tbx2, during early somitogenesis.	TBX18 UNCX	5.87e-05	5	85	2	16958122
Pubmed	Genome wide association study of SNP-, gene-, and pathway-based approaches to identify genes influencing susceptibility to Staphylococcus aureus infections.	BCL11B TXNRD2	5.87e-05	5	85	2	24847357
Pubmed	Epigenetic Thpok silencing limits the time window to choose CD4(+) helper-lineage fate in the thymus.	BCL11B ZBTB7B	5.87e-05	5	85	2	23481257
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	MID1IP1 SEC16A ICE1 ZNF318 RREB1 RUFY1 TANGO6	7.60e-05	418	85	7	34709266
Pubmed	Critical role of CD81 in cognate T-B cell interactions leading to Th2 responses.	TBX18 UNCX	8.80e-05	6	85	2	11978781
Pubmed	Priming of lineage-specifying genes by Bcl11b is required for lineage choice in post-selection thymocytes.	BCL11B ZBTB7B	8.80e-05	6	85	2	28951542
Pubmed	Runx-dependent and silencer-independent repression of a maturation enhancer in the Cd4 gene.	BCL11B ZBTB7B	8.80e-05	6	85	2	30185787
Pubmed	Intronic delay is essential for oscillatory expression in the segmentation clock.	TBX18 UNCX	8.80e-05	6	85	2	21300886
Pubmed	Wdr47 Controls Neuronal Polarization through the Camsap Family Microtubule Minus-End-Binding Proteins.	BCL11B WDR47	1.23e-04	7	85	2	32320668
Pubmed	FoxO6 affects Plxna4-mediated neuronal migration during mouse cortical development.	BCL11B FOXO6	1.23e-04	7	85	2	27791111
Pubmed	Identification of Epha4 enhancer required for segmental expression and the regulation by Mesp2.	TBX18 UNCX	1.23e-04	7	85	2	16728472
Pubmed	Polymorphisms in innate immunity genes and risk of childhood leukemia.	KLK15 ICAM5 C5 KLK1 MASP2	1.55e-04	206	85	5	20438785
Pubmed	Risk of meningioma and common variation in genes related to innate immunity.	KLK15 ICAM5 C5 KLK1 MASP2	1.59e-04	207	85	5	20406964
Pubmed	Common variation in genes related to innate immunity and risk of adult glioma.	KLK15 ICAM5 C5 KLK1 MASP2	1.62e-04	208	85	5	19423540
Pubmed	Hoxb6 can interfere with somitogenesis in the posterior embryo through a mechanism independent of its rib-promoting activity.	TBX18 UNCX	1.64e-04	8	85	2	26718008
Pubmed	Skeletal defects in ringelschwanz mutant mice reveal that Lrp6 is required for proper somitogenesis and osteogenesis.	TBX18 UNCX	1.64e-04	8	85	2	15469977
Pubmed	Differential axial requirements for lunatic fringe and Hes7 transcription during mouse somitogenesis.	TBX18 UNCX	1.64e-04	8	85	2	19956724
Pubmed	Retinoic-acid signalling in node ectoderm and posterior neural plate directs left-right patterning of somitic mesoderm.	TBX18 UNCX	1.64e-04	8	85	2	16489341
Pubmed	Transcriptional oscillation of lunatic fringe is essential for somitogenesis.	TBX18 UNCX	1.64e-04	8	85	2	12670869
Pubmed	Guidance of trunk neural crest migration requires neuropilin 2/semaphorin 3F signaling.	TBX18 UNCX	1.64e-04	8	85	2	16319111
Pubmed	Human transcription factor protein interaction networks.	UBE2O GANAB MID1IP1 TRIP6 AIFM1 SAMD11 ACO2 SEC16A ZNF318 RREB1 KLF4 TANGO6	1.82e-04	1429	85	12	35140242
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	SPTBN4 GPD2 NHSL1 DZANK1 UBE2O TRIO ICAM5 ACO2 SEC16A WNK2 HNRNPU WDR47	1.84e-04	1431	85	12	37142655
Pubmed	The Notch-regulated ankyrin repeat protein is required for proper anterior-posterior somite patterning in mice.	TBX18 UNCX	2.10e-04	9	85	2	21998026
Pubmed	Ctip2/Bcl11b controls ameloblast formation during mammalian odontogenesis.	BCL11B LAMA3	2.10e-04	9	85	2	19251658
Pubmed	The repression of Notch signaling occurs via the destabilization of mastermind-like 1 by Mesp2 and is essential for somitogenesis.	TBX18 UNCX	2.10e-04	9	85	2	21098559
Pubmed	Organization and evolution of the glandular kallikrein locus in Mus musculus.	KLK15 KLK1	2.62e-04	10	85	2	12437987
Pubmed	The negative regulation of Mesp2 by mouse Ripply2 is required to establish the rostro-caudal patterning within a somite.	TBX18 UNCX	2.62e-04	10	85	2	17360776
Pubmed	Segmental border is defined by Ripply2-mediated Tbx6 repression independent of Mesp2.	TBX18 UNCX	2.62e-04	10	85	2	25641698
Pubmed	TSHZ3 and SOX9 regulate the timing of smooth muscle cell differentiation in the ureter by reducing myocardin activity.	TBX18 MYLK	2.62e-04	10	85	2	23671695
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	SPTBN4 MCM3AP SSPOP TANGO6	2.99e-04	130	85	4	12421765
Pubmed	The Eutherian Armcx genes regulate mitochondrial trafficking in neurons and interact with Miro and Trak2.	ARMCX4 ARMCX3	3.20e-04	11	85	2	22569362
Pubmed	Analysis of Ripply1/2-deficient mouse embryos reveals a mechanism underlying the rostro-caudal patterning within a somite.	TBX18 UNCX	3.20e-04	11	85	2	20346937
Pubmed	Defective somite patterning in mouse embryos with reduced levels of Tbx6.	TBX18 UNCX	3.20e-04	11	85	2	12620991
Pubmed	GATA4 Controls Epithelial Morphogenesis in the Developing Stomach to Promote Establishment of Glandular Columnar Epithelium.	KRT13 MUC5AC	3.20e-04	11	85	2	34111600
Pubmed	Transcriptional repression by the T-box proteins Tbx18 and Tbx15 depends on Groucho corepressors.	TBX18 UNCX	3.20e-04	11	85	2	17584735
Pubmed	Specification of vertebral identity is coupled to Notch signalling and the segmentation clock.	TBX18 UNCX	3.83e-04	12	85	2	14960495
Pubmed	Epistatic genetic interactions between Insm1 and Ikzf2 during cochlear outer hair cell development.	BCL11B INSM1	3.83e-04	12	85	2	37171961
Pubmed	Context-Dependent Sensitivity to Mutations Disrupting the Structural Integrity of Individual EGF Repeats in the Mouse Notch Ligand DLL1.	TBX18 UNCX	3.83e-04	12	85	2	26801181
Pubmed	Expression of Notch signaling pathway genes in mouse embryos lacking beta4galactosyltransferase-1.	TBX18 UNCX	3.83e-04	12	85	2	16412699
Pubmed	Appropriate suppression of Notch signaling by Mesp factors is essential for stripe pattern formation leading to segment boundary formation.	TBX18 UNCX	3.83e-04	12	85	2	17306789
Pubmed	Human tissue kallikreins: physiologic roles and applications in cancer.	KLK15 KLK1	4.52e-04	13	85	2	15192120
Pubmed	Disruption of somitogenesis by a novel dominant allele of Lfng suggests important roles for protein processing and secretion.	TBX18 UNCX	4.52e-04	13	85	2	26811377
Pubmed	Differentiation of pluripotent stem cells to muscle fiber to model Duchenne muscular dystrophy.	TBX18 UNCX	4.52e-04	13	85	2	26237517
Pubmed	DIO3 protects against thyrotoxicosis-derived cranio-encephalic and cardiac congenital abnormalities.	GPD2 HR	4.52e-04	13	85	2	36166296
Pubmed	Noncyclic Notch activity in the presomitic mesoderm demonstrates uncoupling of somite compartmentalization and boundary formation.	TBX18 UNCX	4.52e-04	13	85	2	18708576
Pubmed	Fukutin-related protein alters the deposition of laminin in the eye and brain.	BCL11B LAMA3	4.52e-04	13	85	2	21900571
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	TRIM15 LRFN1 TRIP6 SEC16A FGD5 TXNRD2 NOTCH4 TANGO6	5.21e-04	754	85	8	35906200
Pubmed	Differences in Kallikrein-related peptidase mRNA sequences and KLK6 enzyme activity between mouse strains.	KLK15 KLK1	5.27e-04	14	85	2	25666037
Pubmed	Formation and function of the meningeal arachnoid barrier around the developing mouse brain.	TBX18 BCL11B	5.27e-04	14	85	2	36996816
Pubmed	Sequencing and expression analysis of the serine protease gene cluster located in chromosome 19q13 region.	KLK15 KLK1	5.27e-04	14	85	2	11054574
Pubmed	Taxon-specific evolution of glandular kallikrein genes and identification of a progenitor of prostate-specific antigen.	KLK15 KLK1	6.07e-04	15	85	2	15203212
Pubmed	Proceedings of the 1st International Symposium on Kallikreins, Lausanne, Switzerland, September 1-3 , 2005.	KLK15 KLK1	6.07e-04	15	85	2	16800723
Pubmed	A comprehensive nomenclature for serine proteases with homology to tissue kallikreins.	KLK15 KLK1	6.07e-04	15	85	2	16800724
Pubmed	Dynamic CREB family activity drives segmentation and posterior polarity specification in mammalian somitogenesis.	TBX18 UNCX	6.07e-04	15	85	2	23671110
Pubmed	Retinoic acid controls early neurogenesis in the developing mouse cerebral cortex.	BCL11B INSM1	6.07e-04	15	85	2	28790015
Pubmed	Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development.	UNCX NOTCH4	6.07e-04	15	85	2	14672936
Pubmed	Lack of the mesodermal homeodomain protein MEOX1 disrupts sclerotome polarity and leads to a remodeling of the cranio-cervical joints of the axial skeleton.	TBX18 UNCX	6.07e-04	15	85	2	19520072
Pubmed	Zbtb7b engages the long noncoding RNA Blnc1 to drive brown and beige fat development and thermogenesis.	ZBTB7B HNRNPU	6.07e-04	15	85	2	28784777
Pubmed	Tbx18 regulates the development of the ureteral mesenchyme.	TBX18 UNCX	6.93e-04	16	85	2	16511601
Pubmed	Transcription factors Mesp2 and Paraxis have critical roles in axial musculoskeletal formation.	TBX18 UNCX	6.93e-04	16	85	2	17477400
Pubmed	Blood biomarker levels to aid discovery of cancer-related single-nucleotide polymorphisms: kallikreins and prostate cancer.	KLK15 KLK1	6.93e-04	16	85	2	20424135
Pubmed	Breakdown of the reciprocal stabilization of QBRICK/Frem1, Fras1, and Frem2 at the basement membrane provokes Fraser syndrome-like defects.	FREM2 LAMA3	6.93e-04	16	85	2	16880404
Pubmed	Fat4-Dchs1 signalling controls cell proliferation in developing vertebrae.	TBX18 UNCX	6.93e-04	16	85	2	27381226
Pubmed	Wnt3a/beta-catenin signaling controls posterior body development by coordinating mesoderm formation and segmentation.	TBX18 UNCX	7.84e-04	17	85	2	18045842
Pubmed	Foxi3 Deficiency Compromises Hair Follicle Stem Cell Specification and Activation.	KLF4 HR	7.84e-04	17	85	2	26992132
Pubmed	The T-box transcription factor Tbx18 maintains the separation of anterior and posterior somite compartments.	TBX18 UNCX	7.84e-04	17	85	2	15155583
Pubmed	Notch signalling in the paraxial mesoderm is most sensitive to reduced Pofut1 levels during early mouse development.	TBX18 UNCX	7.84e-04	17	85	2	19161597
Pubmed	ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.	GANAB AIFM1 ACO2 ZNF74 WNK2 HNRNPU	8.48e-04	451	85	6	36168627
Pubmed	Intermediate Progenitor Cohorts Differentially Generate Cortical Layers and Require Tbr2 for Timely Acquisition of Neuronal Subtype Identity.	BCL11B INSM1	8.80e-04	18	85	2	27320921
Pubmed	Zic2 and Zic3 synergistically control neurulation and segmentation of paraxial mesoderm in mouse embryo.	TBX18 UNCX	8.80e-04	18	85	2	17490632
Pubmed	Transcriptional repression by FEZF2 restricts alternative identities of cortical projection neurons.	BCL11B KIF26A	8.80e-04	18	85	2	34161768
Pubmed	Targeted disruption of the DM domain containing transcription factor Dmrt2 reveals an essential role in somite patterning.	TBX18 UNCX	8.80e-04	18	85	2	16387292
Pubmed	The murine winged helix transcription factors, Foxc1 and Foxc2, are both required for cardiovascular development and somitogenesis.	TBX18 UNCX	9.83e-04	19	85	2	11562355
Pubmed	Cooperative activity of noggin and gremlin 1 in axial skeleton development.	TBX18 UNCX	9.83e-04	19	85	2	21303853
Pubmed	Coronary arteries form by developmental reprogramming of venous cells.	TBX18 NOTCH4	9.83e-04	19	85	2	20336138
Pubmed	Specific 3-O-sulfated heparan sulfate domains regulate salivary gland basement membrane metabolism and epithelial differentiation.	MYLK LAMA3 KLK1	1.05e-03	81	85	3	39217171
Pubmed	A quantitative survey of gravity receptor function in mutant mouse strains.	SPTBN4 HR	1.09e-03	20	85	2	16235133
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	TRIP6 MCM3AP SEC16A ZNF318	1.10e-03	184	85	4	32908313
Pubmed	A mammalian-specific Alex3/Gαq protein complex regulates mitochondrial trafficking, dendritic complexity, and neuronal survival.	BCL11B ARMCX3	1.20e-03	21	85	2	38320000
Pubmed	Ror2 knockout mouse as a model for the developmental pathology of autosomal recessive Robinow syndrome.	TBX18 UNCX	1.20e-03	21	85	2	14745966
Pubmed	Regulation of cell surface protease matriptase by HAI2 is essential for placental development, neural tube closure and embryonic survival in mice.	KLK15 KLK1	1.20e-03	21	85	2	19592578
Pubmed	Mammalian embryo comparison identifies novel pluripotency genes associated with the naïve or primed state.	TRIP6 KLF4	1.20e-03	21	85	2	30026265
Pubmed	Supt20 is required for development of the axial skeleton.	TBX18 UNCX	1.20e-03	21	85	2	27894818
Pubmed	PDGFRβ regulates craniofacial development through homodimers and functional heterodimers with PDGFRα.	FREM2 LAMA3	1.20e-03	21	85	2	27856617
Pubmed	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	SPTBN4 FREM2 KRT13 GANAB KRT28 NAGLU LAMA3 C5 MASP2	1.21e-03	1070	85	9	23533145
Pubmed	A human MAP kinase interactome.	KRT13 KIF26A CHAF1A MCM3AP LAMA3 WNK2	1.24e-03	486	85	6	20936779
Pubmed	Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter.	TBX18 INSM1 NOTCH4	1.25e-03	86	85	3	35103284
Pubmed	E3 ubiquitin ligase FBXW7 balances airway cell fates.	MUC5AC NOTCH4	1.32e-03	22	85	2	34998785
Pubmed	Trans-differentiation of outer hair cells into inner hair cells in the absence of INSM1.	BCL11B INSM1	1.32e-03	22	85	2	30305733
GeneFamily	Kallikreins	KLK15 KLK1	1.02e-03	16	54	2	616
Coexpression	CAHOY_NEURONAL	BCL11B ICAM5 RPRML AMER3 CRHBP	1.68e-05	100	83	5	M2808
Coexpression	MINGUEZ_LIVER_CANCER_VASCULAR_INVASION_DN	MYLK MASP2 ADH4	3.91e-05	21	83	3	M398
Coexpression	GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_ADULT_UP	ARHGAP6 MYLK TRIO ICE1 RUFY1 APOBR	4.24e-05	200	83	6	M4559
Coexpression	GSE15750_WT_VS_TRAF6KO_DAY6_EFF_CD8_TCELL_DN	SPTBN4 KIF26A ICAM5 CELA1 AMER3 HNRNPU	4.24e-05	200	83	6	M3571
Coexpression	GSE15750_DAY6_VS_DAY10_EFF_CD8_TCELL_DN	BCL11B SEC16A ICE1 ZNF318 RREB1 APOBR	4.24e-05	200	83	6	M3579
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNF150 BCL11B TRANK1 ICAM5 RPRML SLC35D3	1.35e-06	182	85	6	d41ff834b8fc1d0e23cac7ae261de5f72874e462
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNF150 BCL11B TRANK1 ICAM5 RPRML SLC35D3	1.35e-06	182	85	6	6cde859edfe7607bd7ada89d20258413d06f4207
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-7\|TCGA-Prostate / Sample_Type by Project: Shred V9	UBE2O LRFN1 AIFM1 ZBTB7B SSPOP TARBP1	1.35e-06	182	85	6	af16334fec2c757b03c84cf252d00e92fa81e4cd
ToppCell	3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SAMD11 RPRML INSM1 AMER3 HR ADH4	1.49e-06	185	85	6	eb78614c4acf8d2ce7874d7e51e16997b76127ef
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NHSL1 FREM2 LAMA3 GPC5 C5 ADCY8	1.74e-06	190	85	6	8aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCell	TCGA-Kidney-Solid_Tissue_Normal-Kidney-Kidney_normal_tissue\|TCGA-Kidney / Sample_Type by Project: Shred V9	RNF150 UNCX GPC5 C4orf54 CRHBP	1.48e-05	162	85	5	a0367e9af78e4699b9d89d3e0597589e644f844c
ToppCell	TCGA-Kidney-Solid_Tissue_Normal-Kidney\|TCGA-Kidney / Sample_Type by Project: Shred V9	RNF150 UNCX GPC5 C4orf54 CRHBP	1.48e-05	162	85	5	d007ec42d6458431f6c490df61de7a9caef857f0
ToppCell	TCGA-Kidney-Solid_Tissue_Normal\|TCGA-Kidney / Sample_Type by Project: Shred V9	RNF150 UNCX GPC5 C4orf54 CRHBP	1.48e-05	162	85	5	65549ffdbfe8619693345db78e6ddbdde7b742c9
ToppCell	facs-Marrow-B-cells-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBE2O SAMD11 CELA1 TXNRD2 DNAJB3	1.76e-05	168	85	5	08fe8fa43c343c03f9a2f0b982192fde04a7c027
ToppCell	facs-Marrow-B-cells-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBE2O SAMD11 CELA1 TXNRD2 DNAJB3	1.76e-05	168	85	5	d4053b2fffb19e0376b8ceb92e87ec4447d96a3e
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial-N_cells_(NTS+)\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FOXO6 TBC1D30 SAMD11 RPRML INSM1	1.87e-05	170	85	5	02f0be0aab8ba2d35a83238609352ef3677511c9
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NHSL1 FREM2 ICAM5 LAMA3 GPC5	2.03e-05	173	85	5	b799c06a6a5754668e789f70c0c8bc1508568575
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-nan\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF26A LAMA3 CELA1 KLF4 KLK1	2.09e-05	174	85	5	d927504d27b07bbc580bf57c60b383bd28624652
ToppCell	5'-Adult-LargeIntestine-Epithelial-neuro-epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPTBN4 SAMD11 RPRML INSM1 AMER3	2.09e-05	174	85	5	9f114e61458659005b6d0b4aa30a7a059e7aa5c6
ToppCell	5'-Adult-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPTBN4 SAMD11 RPRML INSM1 AMER3	2.14e-05	175	85	5	182e45f5c02214d6b9f317ff5dc43af8b42de978
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic-Paneth\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BCL11B SLC13A1 KLK1 MUC5AC HR	2.26e-05	177	85	5	2af09028014f4ec3b7d2a4c286f1ae5e84a9f590
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPTBN4 FOXO6 RPRML INSM1 ADH4	2.39e-05	179	85	5	f2e8fc975c30992611630197b79daaeef7c4211d
ToppCell	3'_v3-blood-Hematopoietic_Erythro-Mega-Megakaryocyte_early\|blood / Manually curated celltypes from each tissue	ARHGAP6 MYLK SLC35D3 GPC5 RUFY1	2.39e-05	179	85	5	290772eece76d70555dca8b8d82bd88b47e2fc35
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-Tuft-related\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TRIM15 KRT13 APOBR KLK1 WNK2	2.52e-05	181	85	5	1d3d1b5a6efe9cedd03b7e0b5684df97f0246729
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF26A FGD5 ARMCX4 KLF4 NOTCH4	2.52e-05	181	85	5	4d7793026373cbcf04b15c77f95f1025d07d4c00
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TRIM15 KRT13 APOBR KLK1 WNK2	2.52e-05	181	85	5	0069e8308de932df43660bbe926637c57b8bf7f6
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF26A FGD5 ARMCX4 KLF4 NOTCH4	2.66e-05	183	85	5	3427f3cbe6ea81709750e7dd3ff378f03ae65eab
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCL11B TRANK1 ICAM5 RPRML SLC35D3	2.66e-05	183	85	5	bf7f1cb55ed55981b8b355d5774055c96e658ff2
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCL11B TRANK1 ICAM5 RPRML SLC35D3	2.66e-05	183	85	5	9533db4db2c6ae78d7ca1682cf4efed12183396f
ToppCell	P03-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SLC35D3 INSM1 CELA1 XKR4 WNK2	2.73e-05	184	85	5	8880ff36c243cc60a524d74934d000aef26a70ac
ToppCell	droplet-Kidney-nan-3m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF26A FGD5 NOTCH4 HR ADH4	3.02e-05	188	85	5	ec0e241de2c8310b4417b9d4e2420d7a1662f1c0
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCL11B TRANK1 ICAM5 RPRML SLC35D3	3.10e-05	189	85	5	3e8e30160a8d6f531ff743cb5918c9e79481f1bd
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCL11B TRANK1 ICAM5 RPRML SLC35D3	3.10e-05	189	85	5	851f8144aed5c7f80302911cd6b03f14bde7b56d
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCL11B TRANK1 ICAM5 RPRML SLC35D3	3.18e-05	190	85	5	1c5cf933ce71fed5638b9ef31eb81f6c2b6dadbc
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NHSL1 FREM2 LAMA3 C5 ADCY8	3.26e-05	191	85	5	34cc997e4e5c727495f321e6807a84aa124da486
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	TBX18 FREM2 FOXO6 LAMA3 ECHDC2	3.26e-05	191	85	5	4c4eb61e6179d2f8fc524d2f813db9cba84f67a2
ToppCell	wk_20-22-Epithelial-Distal_epithelial_progenitor\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	NHSL1 FREM2 LAMA3 C5 ADCY8	3.34e-05	192	85	5	fa2420d6117d4800f60ef6a24bcf8bf54593cd1f
ToppCell	wk_20-22-Epithelial-Distal_epithelial_progenitor-epi-tip_late\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	NHSL1 FREM2 LAMA3 C5 ADCY8	3.34e-05	192	85	5	87b60014202633a4f6d19b09a5dd9276c2edecfb
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NHSL1 FREM2 LAMA3 GPC5 ADCY8	3.34e-05	192	85	5	fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCell	18-Airway-Epithelial-Bud_tip_adjacent\|Airway / Age, Tissue, Lineage and Cell class	NHSL1 FREM2 LAMA3 GPC5 C5	3.51e-05	194	85	5	b45f1e80074a19245bc5dc4b3a583419a1904404
ToppCell	wk_20-22-Epithelial-Distal_epithelial-type_II_pneumocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	NHSL1 FREM2 LAMA3 C5 ADCY8	3.60e-05	195	85	5	45d1acd316d0ced97dfb150c3a943128d8fa4e7e
ToppCell	wk_15-18-Epithelial-Distal_epithelial-type_II_pneumocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	NHSL1 FREM2 LAMA3 GPC5 C5	3.60e-05	195	85	5	0e3aac1b1a1fd483f5fb9a394eb90c0e1ce63542
ToppCell	wk_20-22-Epithelial-Distal_epithelial\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	NHSL1 FREM2 LAMA3 GPC5 C5	3.69e-05	196	85	5	cd507ee2baf4f52d6498811b3510d3164b56311f
ToppCell	wk_20-22-Epithelial-Distal_epithelial-type_I_pneumocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	NHSL1 FREM2 ICAM5 LAMA3 GPC5	3.69e-05	196	85	5	e24a7aaf41793abba66c1189d933ca05b14c1af9
ToppCell	wk_15-18-Epithelial-Airway_epithelial_progenitor-epi-stalk_late\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	NHSL1 FREM2 LAMA3 GPC5 C5	3.87e-05	198	85	5	1851b7f4198b42c21c934e2fbda39dbd65e2625c
ToppCell	Control_saline-Epithelial_alveolar-AT_1-Differentiating_AT2\|Control_saline / Treatment groups by lineage, cell group, cell type	FREM2 LRP10 ICAM5 LAMA3 C5	4.06e-05	200	85	5	eac33be484dc443794e66e473f03e98406c2983e
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Lhx6\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ARHGAP6 BCL11B SLC35D3 FGD5	8.25e-05	120	85	4	a4e3f9a83bc52ccc75bcd64b1be4e2c5441f6d1a
ToppCell	facs-Marrow-B-cells-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRANK1 GPC5 KLHDC7A SSPOP	1.38e-04	137	85	4	4dcb15de821439011df1bb0bbd7682d674bd725d
ToppCell	facs-Marrow-B-cells-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRANK1 GPC5 KLHDC7A SSPOP	1.38e-04	137	85	4	c05ceeb7b483324604cb3f647d2da2b3786071b1
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1\|343B / Donor, Lineage, Cell class and subclass (all cells)	LRFN1 BCL11B TSNARE1 MUC5AC	1.90e-04	149	85	4	2a7f71da51c85e04de2123164914122480e60d66
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-basal_intermediate_\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	KRT13 FOXO6 LAMA3 HR	2.38e-04	158	85	4	98712ed7e8e65e8c5ff9318cf0e0a04e271a055d
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l44\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BCL11B LRP10 ICAM5 TARBP1	2.49e-04	160	85	4	6b0faaa371650563f585722f5b2fb319e124ec38
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM15 TRANK1 KRT28 MASP2	2.61e-04	162	85	4	22f1abd20f43bc7e7fc46969da9962faf70ae5d2
ToppCell	5'-Adult-SmallIntestine-Epithelial-neuro-epithelial-EECs\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPTBN4 RPRML INSM1 ADH4	2.61e-04	162	85	4	478cf560ef33c5c324142c76417447d4a571a2c9
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM15 TRANK1 KRT28 MASP2	2.61e-04	162	85	4	966df4558140c3d541999ab553f201ae76a1c401
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCL11B TRANK1 SAMD11 ICAM5	2.80e-04	165	85	4	1b7dfa173e83aa8c46a3153a3261866c065c3b73
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCL11B TRANK1 SAMD11 ICAM5	2.80e-04	165	85	4	b4f7d33af7d053ec07b01bd67d861600a9c4822e
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRFN1 LAMA3 FGD5 NOTCH4	2.87e-04	166	85	4	8e2faca6a2e76a625de04d6098aa6f98911945c6
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FREM2 GOLGA6L19 INSM1 KLK1	2.93e-04	167	85	4	5accd0bc7c95089feb2c09376d12cd8bd3773775
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FREM2 TBC1D30 MUC5AC ADH4	3.00e-04	168	85	4	b275e951ff7109e36da22fc17bd4516f9b9432c4
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FREM2 TBC1D30 MUC5AC ADH4	3.00e-04	168	85	4	0757a5af953901a8faed5774ffec4755fc9c0a6e
ToppCell	Control\|World / group, cell type (main and fine annotations)	FREM2 LAMA3 GPC5 MUC5AC	3.00e-04	168	85	4	a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FREM2 TBC1D30 MUC5AC ADH4	3.00e-04	168	85	4	a0dbe2ee697e29b32aa5f8326445e067ff66c154
ToppCell	droplet-Spleen-nan-21m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADRA1B KLK1 MUC5AC HR	3.07e-04	169	85	4	7962165cab84af73d20b56eb70b1ed87c94025ef
ToppCell	facs-Marrow-Granulocytes-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBE2O SAMD11 CELA1 DNAJB3	3.14e-04	170	85	4	b180ec9a1b79025a180c8559c27c31272410dea8
ToppCell	facs-Brain_Myeloid-Striatum-24m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCL11B LAMA3 KLHDC7A ADH4	3.14e-04	170	85	4	626c12b9a51218f72ee32afb5fd5d4b075025d75
ToppCell	368C-Myeloid-Monocyte-CD16+_Monocyte\|Monocyte / Donor, Lineage, Cell class and subclass (all cells)	GPD2 TRANK1 MCM3AP FGD5	3.14e-04	170	85	4	4a19c7e3bb0f9c2601a10debe7000066789b4150
ToppCell	mild_COVID-19-HSPC\|World / disease group, cell group and cell class (v2)	RNF150 ICAM5 LAMA3 CRHBP	3.14e-04	170	85	4	85c476e0bc496445e868a88849960598d97bdea2
ToppCell	facs-Brain_Myeloid-Striatum-24m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCL11B LAMA3 KLHDC7A ADH4	3.14e-04	170	85	4	31daac8696ae8c021c0302d3b30dd8194054b3e7
ToppCell	facs-Marrow-Granulocytes-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBE2O SAMD11 CELA1 DNAJB3	3.14e-04	170	85	4	37c647f67505aa1ff12a198df1eeddd9f406fe15
ToppCell	facs-Brain_Myeloid-Striatum-24m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCL11B LAMA3 KLHDC7A ADH4	3.14e-04	170	85	4	ca88dc0b7a6960facb7c4d3c0f4795431a0a43d2
ToppCell	facs-Brain_Myeloid-Striatum-24m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCL11B LAMA3 KLHDC7A ADH4	3.14e-04	170	85	4	b6882665a27c78a63f3b4a2a8806c8438a98e407
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-6_VIP_RGS16\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FREM2 KIF26A LAMA3 FGD5	3.28e-04	172	85	4	8b396d1e9173da104d467e42286379fe07cee257
ToppCell	PND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FREM2 FOXO6 ICAM5 LAMA3	3.35e-04	173	85	4	45808cf69122c16b9d2b5ffa06d15392c55954b7
ToppCell	PND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FREM2 FOXO6 ICAM5 LAMA3	3.35e-04	173	85	4	7fa9dbcb258c3ab974490063951620e2def03db1
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L3-6_VIP_KCTD13\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	INSM1 LAMA3 FGD5 ZBTB7B	3.35e-04	173	85	4	90e3b9ea3d5f565cfc669e33c4d805b2940a09b3
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KLK15 SLC13A1 KLK1 MUC5AC	3.43e-04	174	85	4	e7cca4b6a3935fad61cf2a3d9984ab1ffa1a9447
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet-Goblet_cell\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KLK15 SLC13A1 KLK1 MUC5AC	3.43e-04	174	85	4	ad5b56f0ace6455c033834b931ec870cc0dc9290
ToppCell	severe_COVID-19-HSPC\|severe_COVID-19 / disease group, cell group and cell class (v2)	RNF150 SAMD11 FGD5 CRHBP	3.43e-04	174	85	4	6d35bacf073537b272ff821e604c899fb9ce6a7c
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-I_cells_(CCK+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPTBN4 RPRML INSM1 AMER3	3.50e-04	175	85	4	c031da47ca63d1133e13530cbf779df9435e22cb
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-Megakaryocyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ARHGAP6 ICAM5 SLC35D3 RUFY1	3.50e-04	175	85	4	b85279b9efd72d7074c4226d50ce139a38c0e1c1
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Hematologic-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBE2O TBC1D30 MASP2	3.53e-04	72	85	3	5e5eb8c7014396767f3dc7d99cb552edd273bfbd
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Hematologic-erythroblast\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBE2O TBC1D30 MASP2	3.53e-04	72	85	3	78e158835ec2a37faadf5acdbb62f266cc184e44
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Hematologic\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBE2O TBC1D30 MASP2	3.53e-04	72	85	3	c4bf1d59845fa54aeb2c8ebeda17bba6641cfb3d
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPTBN4 RPRML INSM1 ADH4	3.58e-04	176	85	4	fb718a6b07aa5d56600263280afa530bcb63db42
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-D_cells_(SST+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPTBN4 RPRML INSM1 AMER3	3.58e-04	176	85	4	da5933eb253f13e70296a50a2bb00ad5c19a2d99
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NHSL1 FGD5 CRHBP NOTCH4	3.58e-04	176	85	4	64e426f5e84884ce2c29acf6f4b958962a63927f
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L6_LHX6_GLP1R\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARHGAP6 GPC5 CRHBP ADCY8	3.66e-04	177	85	4	2b675840b7d2bb536c2c600936733bd9e97e7120
ToppCell	(9)_Platelet\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	ARHGAP6 MYLK SLC35D3 RUFY1	3.66e-04	177	85	4	0830944c43de300815831a9e2b2fce40965e7d12
ToppCell	(9)_Platelet\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	ARHGAP6 MYLK SLC35D3 RUFY1	3.66e-04	177	85	4	e63d01c7fce4fa1256212fa7e95f74281edb3a01
ToppCell	severe_COVID-19-HSPC\|World / disease group, cell group and cell class (v2)	RNF150 SAMD11 FGD5 CRHBP	3.66e-04	177	85	4	289f6aed6f054b04b01659434d8c8b467d1bf5dd
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-Activated_DCs\|Myeloid_cells / Location, Cell class and cell subclass	NHSL1 BCL11B ICAM5 INSM1	3.82e-04	179	85	4	5f7e6670a0e906a0a5bc75735408361d88e78fa2
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_TH\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	UNCX GPC5 CRHBP ADCY8	3.82e-04	179	85	4	797d165718dd1d819e65add3a7859f87b32238a5
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FREM2 ICAM5 LAMA3 GPC5	3.82e-04	179	85	4	cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPTBN4 RPRML INSM1 ADH4	3.82e-04	179	85	4	8ce5000088b727783a0619baa16a2cd036d21f54
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-Activated_DCs\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	NHSL1 RNF150 ACO2 INSM1	3.90e-04	180	85	4	aae85fb3c92a45614616a3ee3a1af5244cc299a7
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF26A MCM3AP LAMA3 HEATR5B	3.98e-04	181	85	4	709e9c7a60d5f98635b99895ce30bb87a9f7376d
ToppCell	10x5'-lymph-node_spleen-Myeloid_Dendritic-migDC\|lymph-node_spleen / Manually curated celltypes from each tissue	RNF150 INSM1 GPC5 HR	3.98e-04	181	85	4	94680f8dbdf22d83801abc0819417751d363fb12
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Akr1c18_Ntf3\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	LAMA3 ZBTB7B CRHBP	3.98e-04	75	85	3	5edf024797a6dd9cbf9916a503194e29e0152d6c
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-6_VIP_RGS16\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FREM2 KIF26A LAMA3 FGD5	4.06e-04	182	85	4	724c33ad2fb525cbcfa5efa3362675eb42a5636d
ToppCell	3'_v3-blood-Hematopoietic_Erythro-Mega\|blood / Manually curated celltypes from each tissue	ARHGAP6 MYLK SLC35D3 GPC5	4.06e-04	182	85	4	3100165c5ba8c3016f9a2f7a8e4ea136750823fe
ToppCell	PCW_05-06-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	INSM1 AMER3 KLK1 MUC5AC	4.06e-04	182	85	4	dc29e8735c3562ce32322351d28f7d9709208ebf
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FREM2 LAMA3 GPC5 ADCY8	4.15e-04	183	85	4	6847c1252d6bb105524f812658112517fd351eab
ToppCell	10x5'v1-week_12-13-Hematopoietic-MK-MK\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ARHGAP6 MYLK SLC35D3 RUFY1	4.15e-04	183	85	4	6cbc88c27dc957d182526e84824f70c8e860bf74
ToppCell	PBMC-Control-Hematopoietic-Platelet-Platelet-plt_3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ARHGAP6 MYLK SLC35D3 RUFY1	4.23e-04	184	85	4	a5d904dd030d9c21be0f8b9ec432025f90fb5b8e
Disease	Malignant neoplasm of breast	KLK15 ICAM5 ACO2 CELA1 FGD5 ZNF318 KLHDC7A RUFY1 NOTCH4 ZNF646	6.40e-04	1074	80	10	C0006142
Disease	hypertension, white matter hyperintensity measurement	TBX18 BCL11B TARBP1	6.47e-04	62	80	3	EFO_0000537, EFO_0005665
Disease	bipolar disorder	BCL11B TRANK1 FOXO6 AIFM1 TSNARE1 TARBP1 WNK2	9.77e-04	577	80	7	MONDO_0004985
Disease	complement factor H-like 1 protein measurement	KLK15 FREM2	1.62e-03	22	80	2	EFO_0600092
Disease	hematocrit	DZANK1 ADRA1B BCL11B UNCX CHAF1A FGD5 RREB1 ZBTB7B NOTCH4	1.65e-03	1011	80	9	EFO_0004348
Disease	susceptibility to pneumonia measurement	ARHGAP6 MUC5AC ADCY8	2.36e-03	97	80	3	EFO_0008410
Disease	transforming growth factor beta measurement	CELA1 HR	2.44e-03	27	80	2	EFO_0004818

Protein segments in the cluster

Peptide	Gene	Start	Entry
LGGICIGVGGADAVD	ACO2	201	Q99798
GREGLASDAGGATVC	AMER3	546	Q8N944
SGGGGDLGFLHLDCA	ADCY8	121	P40145
SRGEGGESGLCSGGQ	LINC00696	51	Q6ZRV3
GGVDFALDCAGGSET	ADH4	266	P08319
IGGGFLGSELACALG	AIFM1	306	O95831
IGGQLGCGSGSTEGE	CDCP2	371	Q5VXM1
GTDGGASNGGCEAAA	ADRA1B	486	P35368
CKTEEEGVGCGGAGR	CHAF1A	181	Q13111
GGSGDVDDAGDCSGA	ARMCX3	41	Q9UH62
CVGAEAGAGAEAGAG	ARMCX4	1806	Q5H9R4
GVLLLAGAGGAAGDE	NAGLU	11	P54802
ATDLESGGAGAACGG	KLF4	71	O43474
LGNAACIGFAGSEGG	KRT28	66	Q7Z3Y7
CIGFAGSEGGLLSGN	KRT28	71	Q7Z3Y7
ASCEDLCGGGVGADG	MYLK	826	Q15746
DILVIGGGATGSGCA	GPD2	71	P43304
GGGATGSGCALDAVT	GPD2	76	P43304
GVDACGDGSDEAGCS	LRP10	161	Q7Z4F1
DVGVEVGGSGGCLEE	MID1IP1	51	Q9NPA3
AGTVSGTGECRQGDG	LAMA3	636	Q16787
GHLEGGKDTCVGDSG	KLK1	201	P06870
CASICGIDGLGDSDG	GRXCR1	46	A8MXD5
EDGCGGSGSGEVKRT	GPC5	501	P78333
GAAGEDGDLGLGSAR	LRFN1	741	Q9P244
ARGCASDGAAGGSEI	ECHDC2	16	Q86YB7
SELLADCGGTIGTDG	FREM2	2646	Q5SZK8
GSDTVGGGRGEECGV	MCM3AP	1006	O60318
AGGFVDFGACDGGLL	KRT13	86	P13646
CGKCQEGLEGGASGA	HR	341	O43593
GALGAAEGCSLDGLA	NHSL1	1546	Q5SYE7
ESSGEAVCLNGAGGG	ICAM5	876	Q9UMF0
GAEGRGAESCEGDSG	KLK15	196	Q9H2R5
GEACGLEGTGAGEDS	FGD5	106	Q6ZNL6
DLGGDSAGRSGAGLE	HNRNPU	61	Q00839
ALGAGVAEGAEDCGP	FOXO6	41	A8MYZ6
GSCEAAAGRAGEAAG	KIF26A	636	Q9ULI4
GTGEAAGGAEEAACH	GOLGA6L19	521	H0YKK7
PDGLVADGEGGCITA	MUC5AC	846	P98088
VCAGGDGVRSGCQGD	CELA1	191	Q9UNI1
ALIGGCGSDEAGAEG	ARHGAP6	41	O43182
CGSDEAGAEGSARGA	ARHGAP6	46	O43182
CGDTGRSGGEALAVA	ICE1	1021	Q9Y2F5
EACTVLGEGGDSGGL	HEATR5B	1691	Q9P2D3
DDDAGGCGDAGAGGA	BCL11B	636	Q9C0K0
GCEGIGDFVELLGGT	CRHBP	236	P24387
DRYGEAGAEGGCTGG	DNAJB3	66	Q8WWF6
FLEKSDLGCGAGGGL	C5	626	P01031
LESGGKDSCRGDSGG	MASP2	621	O00187
GLIAAADGSCAGGEP	KLHDC7A	171	Q5VTJ3
ACLDGGCGAGADGVL	FIGNL2	516	A6NMB9
LLSSAAEGDGGLCGS	DZANK1	551	Q9NVP4
GGGGAGDGTECRDII	C4orf54	336	D6RIA3
GGFALADGCEESGLS	SLC13A1	441	Q9BZW2
EAAGDGEGAGVLGLS	INSM1	421	Q01101
GEGAGVLGLSASAEC	INSM1	426	Q01101
GGGGAELHTEKTECG	RNF150	61	Q9ULK6
CGAALAGAGDLTGDP	SLC35D3	141	Q5M8T2
LEEVDGVGGGAGAAL	RPRML	11	Q8N4K4
GRVAGLCGDFDGDAS	SSPOP	1141	A2VEC9
CGSALRAAAGLGGGD	RUFY1	81	Q96T51
LGLVGLSFCGADVGG	GANAB	636	Q14697
DDVCSFVGGLSGCGE	SAMD11	546	Q96NU1
KGCEGRSGDGACDAG	NOTCH4	1176	Q99466
AGGEGLTTQDAGCGT	APOBR	676	Q0VD83
ESGGAILISAGAGDC	WDR47	721	O94967
GCGEDVVGDGAGVVA	TRIP6	281	Q15654
TGGAGAGVCELDFVG	ZBTB7B	81	O15156
CVGKDGEGDLGPAGT	TSNARE1	56	Q96NA8
LGAGAGSGCAPLEAD	SEC16A	351	O15027
ASGRGEDSGCAALGD	RREB1	841	Q92766
LGAEEAAGAVDDGGC	TBX18	41	O95935
AAGAVDDGGCSRGGG	TBX18	46	O95935
QLGDGGGCTVGVAGE	TRIM15	356	Q9C019
GEEEGRGSSGCSEAG	UBE2O	91	Q9C0C9
GEEGGGTHFCDSLTG	ZNF646	776	O15015
GSGAEDEEAAGGGCC	XKR4	41	Q5GH76
DCKTVVGGGSAAGEG	XKR4	191	Q5GH76
ILEGAGAGAAGGSDA	TANGO6	326	Q9C0B7
CGEELVAAGGAVGPG	SPTBN4	721	Q9H254
SCTEEEEAAGGGRGA	TBC1D30	91	Q9Y2I9
DLLVVGGGSGGLACA	TXNRD2	41	Q9NNW7
GGGSGGLACAKEAAQ	TXNRD2	46	Q9NNW7
GLATAGGVCTEGAAE	TEX13A	161	Q9BXU3
AGAGEGEFVCGECGK	ZNF74	241	Q16587
HGLGGEKALETCGAG	TSPYL6	121	Q8N831
TAVALALGGGGDGDE	TARBP1	166	Q13395
GKELSDSCEGAFGGG	WNK2	1146	Q9Y3S1
ACAGGAGVEPAGDGQ	TRANK1	1116	O15050
SQELVGVDGGGTGCS	ZNF318	336	Q5VUA4
SGCGGGAGEGAEEAA	TRIO	26	O75962
AAATEGGGGDCADAG	UNCX	466	A6NJT0