Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	TBC1D9B SGSM1 ARHGEF28 MCF2L2 RGPD1 ALS2 HMGCR GMIP ARHGAP35 RTKN ARHGEF17 SRGAP3 FARP1 SGSM2 SRGAP1 SESN2	2.11e-05	507	185	16	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	TBC1D9B SGSM1 ARHGEF28 MCF2L2 RGPD1 ALS2 HMGCR GMIP ARHGAP35 RTKN ARHGEF17 SRGAP3 FARP1 SGSM2 SRGAP1 SESN2	2.11e-05	507	185	16	GO:0030695
GeneOntologyMolecularFunction	voltage-gated calcium channel activity	CACHD1 GRM7 RYR1 CACNA1H CACNA1G	6.51e-05	46	185	5	GO:0005245
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	ATP13A4 CACHD1 GRM7 RYR1 ITPR1 CACNA1H CACNA1G SEC61A1	8.39e-05	151	185	8	GO:0015085
GeneOntologyMolecularFunction	calcium channel activity	CACHD1 GRM7 RYR1 ITPR1 CACNA1H CACNA1G SEC61A1	2.02e-04	129	185	7	GO:0005262
GeneOntologyMolecularFunction	low voltage-gated calcium channel activity	CACNA1H CACNA1G	2.55e-04	3	185	2	GO:0008332
Domain	Anaphylatoxin_comp_syst	C3 C4A C4B	8.83e-06	5	181	3	IPR018081
Domain	Anaphylatoxn_comp_syst_dom	C3 C4A C4B	8.83e-06	5	181	3	IPR001840
Domain	ANATO	C3 C4A C4B	3.04e-05	7	181	3	SM00104
Domain	ANAPHYLATOXIN_2	C3 C4A C4B	3.04e-05	7	181	3	PS01178
Domain	ANAPHYLATOXIN_1	C3 C4A C4B	3.04e-05	7	181	3	PS01177
Domain	ANATO	C3 C4A C4B	3.04e-05	7	181	3	PF01821
Domain	Anaphylatoxin/fibulin	C3 C4A C4B	3.04e-05	7	181	3	IPR000020
Domain	MacrogloblnA2_thiol-ester-bond	C3 C4A C4B	4.84e-05	8	181	3	IPR019565
Domain	Thiol-ester_cl	C3 C4A C4B	4.84e-05	8	181	3	PF10569
Domain	MacrogloblnA2_CS	C3 C4A C4B	4.84e-05	8	181	3	IPR019742
Domain	SecY_su_dom	SEC61A2 SEC61A1	9.34e-05	2	181	2	IPR023201
Domain	SECY_1	SEC61A2 SEC61A1	9.34e-05	2	181	2	PS00755
Domain	SECY_2	SEC61A2 SEC61A1	9.34e-05	2	181	2	PS00756
Domain	-	SEC61A2 SEC61A1	9.34e-05	2	181	2	1.10.3370.10
Domain	Translocon_Sec61/SecY_plug_dom	SEC61A2 SEC61A1	9.34e-05	2	181	2	IPR019561
Domain	SecY_CS	SEC61A2 SEC61A1	9.34e-05	2	181	2	IPR030659
Domain	Plug_translocon	SEC61A2 SEC61A1	9.34e-05	2	181	2	PF10559
Domain	MAGEA3/MAGEA6	MAGEA3 MAGEA6	9.34e-05	2	181	2	IPR030097
Domain	SecY	SEC61A2 SEC61A1	9.34e-05	2	181	2	PF00344
Domain	SecY/SEC61-alpha	SEC61A2 SEC61A1	9.34e-05	2	181	2	IPR002208
Domain	A2M	C3 C4A C4B	1.02e-04	10	181	3	PF00207
Domain	A2M_N_2	C3 C4A C4B	1.02e-04	10	181	3	IPR011625
Domain	A2M_comp	C3 C4A C4B	1.02e-04	10	181	3	IPR011626
Domain	A2M_recep	C3 C4A C4B	1.02e-04	10	181	3	PF07677
Domain	A2M_comp	C3 C4A C4B	1.02e-04	10	181	3	PF07678
Domain	A2M_N	C3 C4A C4B	1.02e-04	10	181	3	PF01835
Domain	A2M_N	C3 C4A C4B	1.02e-04	10	181	3	IPR002890
Domain	A-macroglobulin_rcpt-bd	C3 C4A C4B	1.02e-04	10	181	3	IPR009048
Domain	ALPHA_2_MACROGLOBULIN	C3 C4A C4B	1.02e-04	10	181	3	PS00477
Domain	A2M_N_2	C3 C4A C4B	1.02e-04	10	181	3	PF07703
Domain	Macroglobln_a2	C3 C4A C4B	1.02e-04	10	181	3	IPR001599
Domain	VDCC_T_a1	CACNA1H CACNA1G	2.78e-04	3	181	2	IPR005445
Domain	DH_1	ARHGEF28 MCF2L2 ALS2 ARHGEF17 FARP1	3.61e-04	63	181	5	PS00741
Domain	C345C	C3 C4A C4B	5.51e-04	17	181	3	SM00643
Domain	SHR-BD	VPS13C VPS13B	5.53e-04	4	181	2	IPR009543
Domain	VPS13_C	VPS13C VPS13B	5.53e-04	4	181	2	PF16909
Domain	-	C3 C4A	5.53e-04	4	181	2	1.20.91.20
Domain	VPS13_C	VPS13C VPS13B	5.53e-04	4	181	2	IPR031645
Domain	SHR-BD	VPS13C VPS13B	5.53e-04	4	181	2	PF06650
Domain	RhoGEF	ARHGEF28 MCF2L2 ALS2 ARHGEF17 FARP1	5.88e-04	70	181	5	PF00621
Domain	DH_2	ARHGEF28 MCF2L2 ALS2 ARHGEF17 FARP1	5.88e-04	70	181	5	PS50010
Domain	-	ARHGEF28 MCF2L2 ALS2 ARHGEF17 FARP1	6.28e-04	71	181	5	1.20.900.10
Domain	DH-domain	ARHGEF28 MCF2L2 ALS2 ARHGEF17 FARP1	6.28e-04	71	181	5	IPR000219
Domain	Terpenoid_cyclase/PrenylTrfase	C3 C4A C4B	6.56e-04	18	181	3	IPR008930
Domain	NTR	C3 C4A C4B	7.74e-04	19	181	3	PF01759
Domain	Netrin_module_non-TIMP	C3 C4A C4B	7.74e-04	19	181	3	IPR018933
Domain	NUT	NUTM2G NUTM2F	9.16e-04	5	181	2	IPR024310
Domain	NUT_N	NUTM2G NUTM2F	9.16e-04	5	181	2	IPR024309
Domain	NUT	NUTM2G NUTM2F	9.16e-04	5	181	2	PF12881
Domain	HSR	SP100 SP140L	9.16e-04	5	181	2	PS51414
Domain	Autophagy-rel_C	VPS13C VPS13B	9.16e-04	5	181	2	IPR015412
Domain	ATG_C	VPS13C VPS13B	9.16e-04	5	181	2	PF09333
Domain	HSR	SP100 SP140L	9.16e-04	5	181	2	PF03172
Domain	HSR_dom	SP100 SP140L	9.16e-04	5	181	2	IPR004865
Domain	RIH_assoc-dom	RYR1 ITPR1	1.37e-03	6	181	2	IPR013662
Domain	Ins145_P3_rec	RYR1 ITPR1	1.37e-03	6	181	2	PF08709
Domain	RIH_assoc	RYR1 ITPR1	1.37e-03	6	181	2	PF08454
Domain	RIH_dom	RYR1 ITPR1	1.37e-03	6	181	2	IPR000699
Domain	Ins145_P3_rcpt	RYR1 ITPR1	1.37e-03	6	181	2	IPR014821
Domain	Ryanodine_recept-rel	RYR1 ITPR1	1.37e-03	6	181	2	IPR015925
Domain	-	RYR1 ITPR1	1.37e-03	6	181	2	1.25.10.30
Domain	RYDR_ITPR	RYR1 ITPR1	1.37e-03	6	181	2	PF01365
Domain	NTR	C3 C4A C4B	1.37e-03	23	181	3	PS50189
Domain	Netrin_domain	C3 C4A C4B	1.37e-03	23	181	3	IPR001134
Domain	F_BAR	GMIP SRGAP3 SRGAP1	1.76e-03	25	181	3	IPR031160
Domain	F_BAR	GMIP SRGAP3 SRGAP1	1.76e-03	25	181	3	PS51741
Domain	Peptidase_M13_C	PHEX MMEL1	1.90e-03	7	181	2	IPR018497
Domain	Peptidase_M13	PHEX MMEL1	1.90e-03	7	181	2	IPR000718
Domain	Peptidase_M13_N	PHEX MMEL1	1.90e-03	7	181	2	PF05649
Domain	Peptidase_M13_N	PHEX MMEL1	1.90e-03	7	181	2	IPR008753
Domain	Peptidase_M13	PHEX MMEL1	1.90e-03	7	181	2	PF01431
Domain	-	INPP5D ANGEL2 DNASE1	1.98e-03	26	181	3	3.60.10.10
Domain	TIMP-like_OB-fold	C3 C4A C4B	1.98e-03	26	181	3	IPR008993
Domain	Exo_endo_phos	INPP5D ANGEL2 DNASE1	1.98e-03	26	181	3	PF03372
Domain	Endo/exonuclease/phosphatase	INPP5D ANGEL2 DNASE1	2.21e-03	27	181	3	IPR005135
Domain	Kinase-like_dom	CDKL2 MARK1 WDR81 ARHGAP35 TYK2 LIMK2 CAMKK2 PIK3C2G NEK5 RPS6KA6 SIK2 MAP3K9 STKLD1	2.46e-03	542	181	13	IPR011009
Domain	SAND_dom	SP100 SP140L	2.52e-03	8	181	2	IPR000770
Domain	Chorein_N	VPS13C VPS13B	2.52e-03	8	181	2	PF12624
Domain	VPS13_N	VPS13C VPS13B	2.52e-03	8	181	2	IPR026854
Domain	SAND	SP100 SP140L	2.52e-03	8	181	2	PF01342
Domain	A2M_N_2	C3 C4A	2.52e-03	8	181	2	SM01359
Domain	-	C3 C4A	2.52e-03	8	181	2	2.60.40.690
Domain	A2M_recep	C3 C4A	2.52e-03	8	181	2	SM01361
Domain	A2M	C3 C4A	2.52e-03	8	181	2	SM01360
Domain	SAND	SP100 SP140L	2.52e-03	8	181	2	PS50864
Domain	SAND	SP100 SP140L	2.52e-03	8	181	2	SM00258
Domain	AMP-binding	DIP2B AACS ACSM2A	3.00e-03	30	181	3	PF00501
Domain	AMP-dep_Synth/Lig	DIP2B AACS ACSM2A	3.00e-03	30	181	3	IPR000873
Domain	PH_dom-like	ARHGEF28 SPTBN2 MCF2L2 RGPD1 ALS2 RTKN ARHGEF17 LYST TYK2 FARP1 APPL1	3.01e-03	426	181	11	IPR011993
Domain	RhoGAP	GMIP ARHGAP35 SRGAP3 SRGAP1	3.07e-03	62	181	4	SM00324
Domain	BEACH	WDR81 LYST	3.22e-03	9	181	2	PS50197
Domain	Beach	WDR81 LYST	3.22e-03	9	181	2	PF02138
Domain	-	WDR81 LYST	3.22e-03	9	181	2	1.10.1540.10
Domain	NHL_repeat_subgr	NHLRC2 PAM	3.22e-03	9	181	2	IPR013017
Domain	Beach	WDR81 LYST	3.22e-03	9	181	2	SM01026
Domain	BEACH_dom	WDR81 LYST	3.22e-03	9	181	2	IPR000409
Domain	RhoGAP	GMIP ARHGAP35 SRGAP3 SRGAP1	3.26e-03	63	181	4	PF00620
Domain	RhoGAP_dom	GMIP ARHGAP35 SRGAP3 SRGAP1	3.45e-03	64	181	4	IPR000198
Domain	RHOGAP	GMIP ARHGAP35 SRGAP3 SRGAP1	3.45e-03	64	181	4	PS50238
Domain	-	GMIP ARHGAP35 SRGAP3 SRGAP1	3.45e-03	64	181	4	1.10.555.10
Pathway	REACTOME_ACTIVATION_OF_C3_AND_C5	C3 C4A C4B	3.26e-05	7	140	3	MM14685
Pathway	REACTOME_ACTIVATION_OF_C3_AND_C5	C3 C4A C4B	5.18e-05	8	140	3	M27031
Pathway	PID_RHOA_REG_PATHWAY	ARHGEF28 ARHGAP35 ARHGEF17 FARP1 SRGAP1	8.89e-05	46	140	5	M68
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	DIP2B ARHGEF28 YTHDC2 GMIP EZH2 PIAS1 DPM1 ITPR1 TYK2 TTLL12 PRR12 PARP4 GTF3C1 AACS SIK2 PAM C4A C4B SEC61A1 HELLS	3.95e-10	650	186	20	38777146
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	ESYT1 SPTBN2 ASCC1 UBE2M CPD CEP192 PRPF8 NDUFS2 DMXL1 ITPR1 TTLL12 SEC61A2 CNNM3 CACTIN URB1 CAMKK2 MDN1 FARP1 STAU2 SNRNP40 SIK2 EIF5B MRPL38 SEC61A1 CLUH VPS13B ATP5F1B HELLS	7.27e-09	1487	186	28	33957083
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	TPR DIP2B FLNB RAN ESYT1 SPTBN2 ARHGAP35 ECPAS PRPF8 DPM1 ATAD1 SRGAP3 FARP1 VCAN SNRNP40 EIF5B	1.34e-08	498	186	16	36634849
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	FLNB SGSM1 CDKL2 VPS13C SPTBN2 ECPAS PRPF8 ARHGEF17 NDUFS2 RYR1 TTLL12 PARP4 URB1 MDN1 GTF3C1 SRGAP3 MAP3K9 CPSF1 SP7	1.89e-08	736	186	19	29676528
Pubmed	Protection from Streptococcus pneumoniae infection by C-reactive protein and natural antibody requires complement but not Fc gamma receptors.	FCGR2A C3 C4A C4B	2.74e-08	7	186	4	12055255
Pubmed	Divergent immunoglobulin g subclass activity through selective Fc receptor binding.	FCGR2A C3 C4A C4B	5.45e-08	8	186	4	16322460
Pubmed	Impaired antibody response causes persistence of prototypic T cell-contained virus.	FCGR2A C3 C4A C4B	5.45e-08	8	186	4	19355789
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	FLNB RAN TBC1D9B ESYT1 SPTBN2 ASCC1 YTHDC2 HMGCR COPS3 MCCC1 ECPAS PRPF8 IFIT1 DPM1 NDUFS2 ITPR1 URB1 MDN1 GTF3C1 ATAD1 STAU2 SNRNP40 EIF5B SEC61A1 ATP5F1B HELLS	6.10e-08	1440	186	26	30833792
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	RAN SPTBN2 ASCC1 YTHDC2 AK9 COPS3 ECPAS PRPF8 DPM1 MDN1 GTF3C1 CPSF1 C4A C4B HELLS	8.70e-08	497	186	15	36774506
Pubmed	Genetic polymorphism of murine C3 controlled by a single co-dominant locus on chromosome 17.	C3 C4A C4B	1.51e-07	3	186	3	681746
Pubmed	Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity.	C3 C4A C4B	1.51e-07	3	186	3	8524789
Pubmed	Immune complex glomerulonephritis in C4- and C3-deficient mice.	C3 C4A C4B	1.51e-07	3	186	3	9461092
Pubmed	Regulation of the B cell response to T-dependent antigens by classical pathway complement.	C3 C4A C4B	1.51e-07	3	186	3	8752901
Pubmed	Complement genes contribute sex-biased vulnerability in diverse disorders.	C3 C4A C4B	1.51e-07	3	186	3	32499649
Pubmed	Role of complement in a murine model of peanut-induced anaphylaxis.	C3 C4A C4B	1.51e-07	3	186	3	23182714
Pubmed	Serum complement component 3, complement component 4 and complement component 1q levels predict progressive visual field loss in older women with primary angle closure glaucoma.	C3 C4A C4B	1.51e-07	3	186	3	35017157
Pubmed	Genetic evidence for involvement of classical complement pathway in induction of experimental autoimmune myasthenia gravis.	C3 C4A C4B	1.51e-07	3	186	3	14500686
Pubmed	In vitro C3 deposition on Cryptococcus capsule occurs via multiple complement activation pathways.	C3 C4A C4B	1.51e-07	3	186	3	21723612
Pubmed	Acute nephrotoxic serum nephritis in complement knockout mice: relative roles of the classical and alternate pathways in neutrophil recruitment and proteinuria.	C3 C4A C4B	1.51e-07	3	186	3	9829481
Pubmed	Three distinct profiles of serum complement C4 proteins in pediatric systemic lupus erythematosus (SLE) patients: tight associations of complement C4 and C3 protein levels in SLE but not in healthy subjects.	C3 C4A C4B	1.51e-07	3	186	3	16893076
Pubmed	Complement C4-deficient mice have a high mortality rate during PTZ-induced epileptic seizures, which correlates with cognitive problems and the deficiency in the expression of Egr1 and other immediate early genes.	C3 C4A C4B	1.51e-07	3	186	3	37234916
Pubmed	Epithelial secretion of C3 promotes colonization of the upper urinary tract by Escherichia coli.	C3 C4A C4B	1.51e-07	3	186	3	11433344
Pubmed	Increased susceptibility to endotoxin shock in complement C3- and C4-deficient mice is corrected by C1 inhibitor replacement.	C3 C4A C4B	1.51e-07	3	186	3	9218619
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	TPR FLNB RAN DNAH10 VPS13C ESYT1 YTHDC2 UBE2M COPS3 ECPAS PRPF8 DPM1 NDUFS2 TTLL12 URB1 MDN1 GTF3C1 SNRNP40 EIF5B CPSF1 SEC61A1 NNT CLUH ATP5F1B HELLS	1.93e-07	1425	186	25	30948266
Pubmed	The Immunological Organ Environment Dictates the Molecular and Cellular Pathways of Cytotoxic Antibody Activity.	FCGR2A C3 C4A C4B	3.79e-07	12	186	4	31801071
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	ERAP1 ALS2 ARHGAP35 C2CD2L URB1 CAMKK2 SRGAP3 SIK2 APPL1 CACNA1G	4.16e-07	225	186	10	12168954
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	DIP2B VPS13C ESYT1 YTHDC2 CPD IFIT1 NDUFS2 ITPR1 C2CD2L SEC61A2 SNIP1 MDN1 ATAD1 ANGEL2 STAU2 BRD7 CPSF1 MRPL38 ACOT2 PRORP SEC61A1 NNT CLUH VPS13B ATP5F1B	4.75e-07	1496	186	25	32877691
Pubmed	Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.	RAN MARK1 SPTBN2 LAMA3 YTHDC2 PRPF8 DPM1 RYR1 PARP4 GTF3C1 MSMO1 STAU2 EIF5B CKAP2L C3 C4A ATP5F1B	4.82e-07	732	186	17	34732716
Pubmed	VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.	TBC1D9B ALS2 UBE2M COPS3 HS1BP3 PTPN9 MDN1 GTF3C1 APPL1 SESN2 HELLS	4.93e-07	288	186	11	23383273
Pubmed	Impaired mast cell-dependent natural immunity in complement C3-deficient mice.	C3 C4A C4B	6.00e-07	4	186	3	9367154
Pubmed	Complement C4 is protective for lupus disease independent of C3.	C3 C4A C4B	6.00e-07	4	186	3	11801636
Pubmed	A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo.	C3 C4A C4B	6.00e-07	4	186	3	10934224
Pubmed	Intestinal reperfusion injury is mediated by IgM and complement.	C3 C4A C4B	6.00e-07	4	186	3	10066708
Pubmed	Antigen localization within the splenic marginal zone restores humoral immune response and IgG class switch in complement C4-deficient mice.	C3 C4A C4B	6.00e-07	4	186	3	15477230
Pubmed	Phylogeny of the C3/C4/C5 complement-component gene family indicates that C5 diverged first.	C3 C4A C4B	6.00e-07	4	186	3	8015436
Pubmed	The alternative activation pathway and complement component C3 are critical for a protective immune response against Pseudomonas aeruginosa in a murine model of pneumonia.	C3 C4A C4B	6.00e-07	4	186	3	15102802
Pubmed	Macrophages from C3-deficient mice have impaired potency to stimulate alloreactive T cells.	C3 C4A C4B	6.00e-07	4	186	3	16304047
Pubmed	Efficient amyloid A clearance in the absence of immunoglobulins and complement factors.	C3 C4A C4B	6.00e-07	4	186	3	23454183
Pubmed	The human complement system: assembly of the classical pathway C3 convertase.	C3 C4A C4B	6.00e-07	4	186	3	6906228
Pubmed	Functional analysis of Ficolin-3 mediated complement activation.	C3 C4A C4B	6.00e-07	4	186	3	21085669
Pubmed	Protection against anti-glomerular basement membrane (GBM)-mediated nephritis in C3- and C4-deficient mice.	C3 C4A C4B	6.00e-07	4	186	3	9409643
Pubmed	Complement Activation Contributes to Severe Acute Respiratory Syndrome Coronavirus Pathogenesis.	C3 C4A C4B	6.00e-07	4	186	3	30301856
Pubmed	Allelic distribution of complement components BF, C4A, C4B, and C3 in Psoriasis vulgaris.	C3 C4A C4B	6.00e-07	4	186	3	11803045
Pubmed	Complement classical pathway components are all important in clearance of apoptotic and secondary necrotic cells.	C3 C4A C4B	6.00e-07	4	186	3	19302245
Pubmed	Evidence for non-traditional activation of complement factor C3 during murine liver regeneration.	C3 C4A C4B	6.00e-07	4	186	3	18452991
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	ETS1 WDR81 ALS2 MIER1 ITPR1 MDN1 FARP1 STAU2 RPS6KA6 EIF5B CACNA1G PRL	6.84e-07	363	186	12	14691545
Pubmed	Defining the membrane proteome of NK cells.	PPP1R21 DIP2B RAN MAN1A1 ERAP1 ESYT1 CPD ECPAS PRPF8 DPM1 ITPR1 CNNM3 PARP4 MDN1 GTF3C1 ATAD1 STAU2 PAM NNT PIGO ATP5F1B	1.35e-06	1168	186	21	19946888
Pubmed	The generation of thymus-independent germinal centers depends on CD40 but not on CD154, the T cell-derived CD40-ligand.	C3 C4A C4B	1.49e-06	5	186	3	16783845
Pubmed	Local production and activation of complement up-regulates the allostimulatory function of dendritic cells through C3a-C3aR interaction.	C3 C4A C4B	1.49e-06	5	186	3	18056835
Pubmed	Complement proteins C3 and C4 bind to collagen and elastin in the vascular wall: a potential role in vascular stiffness and atherosclerosis.	C3 C4A C4B	1.49e-06	5	186	3	21707943
Pubmed	Role of complement receptors 1 and 2 (CD35 and CD21), C3, C4, and C5 in survival by mice of Staphylococcus aureus bacteremia.	C3 C4A C4B	1.49e-06	5	186	3	15192652
Pubmed	A role for Mac-1 (CDIIb/CD18) in immune complex-stimulated neutrophil function in vivo: Mac-1 deficiency abrogates sustained Fcgamma receptor-dependent neutrophil adhesion and complement-dependent proteinuria in acute glomerulonephritis.	C3 C4A C4B	1.49e-06	5	186	3	9382884
Pubmed	Protective T cell-independent antiviral antibody responses are dependent on complement.	C3 C4A C4B	1.49e-06	5	186	3	10523614
Pubmed	Stromal complement receptor CD21/35 facilitates lymphoid prion colonization and pathogenesis.	C3 C4A C4B	1.49e-06	5	186	3	17947689
Pubmed	The C5 convertase is not required for activation of the terminal complement pathway in murine experimental cerebral malaria.	C3 C4A C4B	1.49e-06	5	186	3	22689574
Pubmed	Predominant role for C5b-9 in renal ischemia/reperfusion injury.	C3 C4A C4B	1.49e-06	5	186	3	10811844
Pubmed	Intranasal peptide-induced tolerance and linked suppression: consequences of complement deficiency.	C3 C4A C4B	1.49e-06	5	186	3	25039245
Pubmed	Both complement and IgG fc receptors are required for development of attenuated antiglomerular basement membrane nephritis in mice.	C3 C4A C4B	1.49e-06	5	186	3	19710463
Pubmed	Classical and alternative complement activation on photoreceptor outer segments drives monocyte-dependent retinal atrophy.	C3 C4A C4B	1.49e-06	5	186	3	29743491
Pubmed	Formation of high affinity C5 convertase of the classical pathway of complement.	C3 C4A C4B	1.49e-06	5	186	3	12878586
Pubmed	Complement C4A Regulates Autoreactive B Cells in Murine Lupus.	C3 C4A C4B	1.49e-06	5	186	3	33147456
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	TPR DIP2B FLNB ESYT1 PRPF8 MDN1 EIF5B C3 USP4 NNT ATP5F1B	2.77e-06	344	186	11	30333137
Pubmed	Predominant role of IgM-dependent activation of the classical pathway in the clearance of dying cells by murine bone marrow-derived macrophages in vitro.	C3 C4A C4B	2.97e-06	6	186	3	15597324
Pubmed	CD21/35 promotes protective immunity to Streptococcus pneumoniae through a complement-independent but CD19-dependent pathway that regulates PD-1 expression.	C3 C4A C4B	2.97e-06	6	186	3	19710450
Pubmed	Burn injury reveals altered phenotype in mannan-binding lectin-deficient mice.	C3 C4A C4B	2.97e-06	6	186	3	17363917
Pubmed	Modulation of the antitumor immune response by complement.	C3 C4A C4B	2.97e-06	6	186	3	18820683
Pubmed	A dominant complement fixation pathway for pneumococcal polysaccharides initiated by SIGN-R1 interacting with C1q.	C3 C4A C4B	2.97e-06	6	186	3	16615889
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	TPR FLNB RAN ERAP1 ESYT1 CPD MCCC1 PRPF8 IFIT1 MIER1 DPM1 NDUFS2 ITPR1 SNIP1 GORASP2 ATAD1 MSMO1 FARP1 CPSF1 PAM SEC61A1 PIGO ATP5F1B	3.43e-06	1451	186	23	30550785
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	TPR FLNB RAN SP100 ESYT1 SPTBN2 ASCC1 LAMA3 YTHDC2 PRPF8 DPM1 NDUFS2 GTF3C1 SRGAP1 ANGEL2 STAU2 SNRNP40 EIF5B CPSF1 C3 ATP5F1B	4.24e-06	1257	186	21	36526897
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DIP2B ARHGEF28 ESYT1 ALS2 CEP192 MCCC1 RTKN ARHGEF17 LYST TTLL12 UNC119 LIMK2 MDN1 SLF2 SRGAP1 SIK2 MAP3K9	4.31e-06	861	186	17	36931259
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	TPR DIP2B YTHDC2 ARHGAP35 ECPAS GTF2IRD1 EZH2 MIER1 CACTIN MDN1 GTF3C1 EIF5B CPSF1 APPL1 CLUH ZMYM4	4.70e-06	774	186	16	15302935
Pubmed	Complement component C3 binds to activated normal platelets without preceding proteolytic activation and promotes binding to complement receptor 1.	C3 C4A C4B	5.19e-06	7	186	3	20139276
Pubmed	A platelet-mediated system for shuttling blood-borne bacteria to CD8α+ dendritic cells depends on glycoprotein GPIb and complement C3.	C3 C4A C4B	5.19e-06	7	186	3	22037602
Pubmed	Complement C3a signaling facilitates skeletal muscle regeneration by regulating monocyte function and trafficking.	C3 C4A C4B	5.19e-06	7	186	3	29233958
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	DIP2B FLNB RAN ESYT1 YTHDC2 CPD NHLRC2 ECPAS PRPF8 TYK2 CNNM3 PTPN9 GTF3C1 C3 PRORP SEC61A1 CLUH ATP5F1B	5.53e-06	974	186	18	28675297
Pubmed	Antibodies and complement are key drivers of thrombosis.	FCGR2A C3 C4A C4B	6.48e-06	23	186	4	39226900
Pubmed	Functional genomic landscape of cancer-intrinsic evasion of killing by T cells.	ERAP1 HIKESHI UBE2M LYST NDUFS2 CFLAR WDR45 MSMO1 SP140L SNRNP40 MNAT1 PRL	7.30e-06	457	186	12	32968282
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	MAN1A1 ERAP1 ESYT1 CPD HMGCR CACHD1 ADGRE2 DMXL1 ITPR1 CNNM3 GORASP2 GTF3C1 CELSR3 MSMO1 CPSF1 PAM C4A SEC61A1 PIGO ATP5F1B	7.64e-06	1201	186	20	35696571
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	FLNB RAN ESYT1 WDR81 UBE2M COPS3 NHLRC2 MCCC1 ECPAS PRPF8 RYR1 MDN1 EIF5B CACNA1G NNT ATP5F1B	7.92e-06	807	186	16	30575818
Pubmed	C3 opsonization regulates endocytic handling of apoptotic cells resulting in enhanced T-cell responses to cargo-derived antigens.	C3 C4A C4B	8.26e-06	8	186	3	24474777
Pubmed	Two quantitative trait loci affecting progressive hearing loss in 101/H mice.	CDH23 CTNNA3 CACNA1H	8.26e-06	8	186	3	16897347
Pubmed	The role of complement in cryoglobulin-induced immune complex glomerulonephritis.	C3 C4A C4B	8.26e-06	8	186	3	16272350
Pubmed	Essential role of complement mannose-binding lectin-associated serine proteases-1/3 in the murine collagen antibody-induced model of inflammatory arthritis.	C3 C4A C4B	8.26e-06	8	186	3	20870940
Pubmed	Synergy between the classical and alternative pathways of complement is essential for conferring effective protection against the pandemic influenza A(H1N1) 2009 virus infection.	C3 C4A C4B	8.26e-06	8	186	3	28301559
Pubmed	Neurons under T Cell Attack Coordinate Phagocyte-Mediated Synaptic Stripping.	C3 C4A C4B	8.26e-06	8	186	3	30173917
Pubmed	Negligible role of antibodies and C5 in pregnancy loss associated exclusively with C3-dependent mechanisms through complement alternative pathway.	C3 C4A C4B	8.26e-06	8	186	3	14670299
Pubmed	Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis.	SGSM1 ARHGEF28 UBE2M PRPF8 GTF3C1 USP4 TSHZ1 DNASE1 ATP5F1B	8.59e-06	249	186	9	9371744
Pubmed	Surviving mousepox infection requires the complement system.	C3 C4A C4B	1.23e-05	9	186	3	19112490
Pubmed	Uterine-specific Ezh2 deletion enhances stromal cell senescence and impairs placentation, resulting in pregnancy loss.	EZH2 PGR PRL	1.23e-05	9	186	3	37360688
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	TPR FLNB SPTBN2 YTHDC2 ECPAS PRPF8 TTLL12 URB1 MDN1 GTF3C1 EIF5B CPSF1 NNT CLUH	1.26e-05	653	186	14	22586326
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	TPR FLNB PRPF8 DPM1 PRR12 URB1 MDN1 GTF3C1 FARP1 SNRNP40 CPSF1 C1D C4A SEC61A1 ZMYM4 ATP5F1B	1.44e-05	847	186	16	35850772
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	DIP2B FLNB SGSM1 MORN1 VPS13C LAMA3 CPD CEP192 ARHGAP35 ECPAS GTF2IRD1 UBLCP1 TYK2 GTF3C1 FARP1 SGSM2 CACNA1H XYLB GREB1 PRORP VPS13B ZMYM4	1.69e-05	1489	186	22	28611215
Pubmed	Complement Inhibitor CRIg/FH Ameliorates Renal Ischemia Reperfusion Injury via Activation of PI3K/AKT Signaling.	C3 C4A C4B	1.76e-05	10	186	3	30429287
Pubmed	Mechanisms of mannose-binding lectin-associated serine proteases-1/3 activation of the alternative pathway of complement.	C3 C4A C4B	1.76e-05	10	186	3	21943708
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	SPTBN2 ECPAS ARHGEF17 MDN1 IGSF1 PRORP	2.12e-05	104	186	6	9205841
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	RAN MCCC1 GTF2IRD1 EZH2 PRPF8 MIER1 DPM1 LIN9 PRR12 SNIP1 CACTIN URB1 MDN1 GTF3C1 SLF2 SNRNP40 CPSF1 ZMYM4 ATP5F1B HELLS	2.23e-05	1294	186	20	30804502
Pubmed	Combination of factor H mutation and properdin deficiency causes severe C3 glomerulonephritis.	C3 C4A C4B	2.41e-05	11	186	3	23204401
Pubmed	Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.	THSD4 FLNB MDN1 GTF3C1 VCAN SEC61A1 ATP5F1B HELLS	2.54e-05	219	186	8	31353912
Pubmed	SARS-CoV-2 uses Spike glycoprotein to control the host's anaerobic metabolism by inhibiting LDHB.	TPR ESYT1 UBE2M ECPAS PRPF8 NDUFS2 TTLL12 SNRNP40 EIF5B CPSF1 C3 NNT CLUH	2.62e-05	607	186	13	39147351
Pubmed	Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.	C4A C4B	2.84e-05	2	186	2	22737222
Cytoband	2q37.1	SP100 INPP5D TIGD1 SP140L	1.64e-04	67	186	4	2q37.1
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	C3 C4A C4B	2.27e-05	9	119	3	1234
GeneFamily	Small G protein signaling modulators	SGSM1 SGSM2	1.28e-04	3	119	2	751
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	PPP1R21 WDR81 CEP192 GRM7 RYR1 ITPR1 FARP1	1.96e-04	181	119	7	694
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	GMIP ARHGAP35 SRGAP3 SRGAP1	3.25e-04	50	119	4	721
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	MCF2L2 ALS2 ARHGEF17 FARP1	9.39e-04	66	119	4	722
GeneFamily	WD repeat domain containing\|BEACH domain containing	WDR81 LYST	1.50e-03	9	119	2	1230
GeneFamily	Complement system\|Sushi domain containing	C3 C4A C4B	1.69e-03	36	119	3	492
Coexpression	NAKAYA_MYELOID_DENDRITIC_CELL_FLUARIX_FLUVIRIN_AGE_18_50YO_7DY_UP	SP100 LILRA2 TBC1D9B ERAP1 YTHDC2 CPD SOCS6 ITPR1 PARP4 PTPN9 CAMKK2 SLF2 USP4 ZMYM4	1.03e-06	399	185	14	M41172
CoexpressionAtlas	FacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_1000_k-means-cluster#4	UBE2M XPNPEP2 ECPAS GTF2IRD1 LIN9 GTF3C1 SLF2 RPS6KA6 C1D XYLB	1.21e-05	203	185	10	Facebase_RNAseq_e9.5_Mandibular Arch_1000_K4
ToppCell	Tracheal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	THSD4 FLNB ARHGEF28 MUC16 CPD LIMK2 SRGAP3 FARP1 SRGAP1 AACS	1.30e-08	200	186	10	d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	XPNPEP2 LGSN IDO2 SLC6A13 FARP1 XYLB GREB1 ACSM2A	1.02e-06	182	186	8	4a9c13932e7163fd37a3dcc4c6ca3bbea5372459
ToppCell	Bronchial-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	THSD4 ATP13A4 CDKL2 LAMA3 CACHD1 MCCC1 FARP1 LRP2BP	1.98e-06	199	186	8	5f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-dn_T\|COVID-19_Mild / Disease, condition lineage and cell class	FLNB ESYT1 ETS1 LYST IFIT1 SLC6A13 PARP4 PAM	1.98e-06	199	186	8	f307d4887b28cf60a591439e278fd668409cb104
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	THSD4 ARHGEF28 MUC16 CPD MSMO1 FARP1 SRGAP1 AACS	2.06e-06	200	186	8	0eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LGSN IDO2 SLC6A13 FARP1 XYLB GREB1 ACSM2A	9.77e-06	177	186	7	2f81b26be89cc2fd8eafadaf7eae3c6ad6521462
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MAN1A1 CACHD1 ITPR1 PIK3C2G NNT DNASE1 CDH16	1.21e-05	183	186	7	2f0ee40e69ad1259e56e8ee4b352736900eb8901
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ATP13A4 ARHGEF28 LAMA3 PIK3C2G CTNNA3 MAP3K9 CDH16	1.40e-05	187	186	7	db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	LAMA3 AK9 EZH2 LHFPL1 EIF5B CFAP161 HELLS	1.44e-05	188	186	7	0476d7ee3e0ce78c3c5b111e9ade01098f9ea7ec
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PABPC1L2A PON1 GRM7 VCAN CACNA1G FGF14 NOS1	1.55e-05	190	186	7	6c7e1086c0a274cd5527c3104106e372811c9905
ToppCell	Control-Epithelial_alveolar-Mes-Like-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATP13A4 DNAH10 LAMA3 CFAP161 PRORP CLUH	1.57e-05	127	186	6	556aaf88719c83f307fa50dfac151136ed05c8ad
ToppCell	medial-2-Hematologic-Nonclassical_Monocyte\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	LILRA2 CDH23 ADGRE2 LYST UNC119 TBATA LTB	1.77e-05	194	186	7	202e5070728191c46161fa7d931f00be1c7559d4
ToppCell	medial-Hematologic-Nonclassical_Monocyte-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	LILRA2 CDH23 ADGRE2 LYST UNC119 TBATA LTB	1.77e-05	194	186	7	002cd317732fc6b0d9a72fb46199f71db5a638a7
ToppCell	medial-Hematologic-Nonclassical_Monocyte\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	LILRA2 CDH23 ADGRE2 LYST UNC119 TBATA LTB	1.77e-05	194	186	7	ac203d388a3a3884e316dec0dcbd408e43c6ef6c
ToppCell	(001)_CD16+_Monocyte\|World / immune cells in Peripheral Blood (logTPM normalization)	LILRA2 CDH23 ADGRE2 LYST UNC119 FCGR2A C3	1.89e-05	196	186	7	33843d550cbca03c044d593b1f6972e4d3871f7f
ToppCell	distal-Hematologic-Nonclassical_Monocyte-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	LILRA2 CDH23 XPNPEP2 ADGRE2 LYST UNC119 LTB	1.95e-05	197	186	7	e817c1a8549e403e723b1b6c73cdb04f1179909d
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	THSD4 ATP13A4 CDKL2 LAMA3 CACHD1 MCCC1 LRP2BP	2.08e-05	199	186	7	725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCell	Sepsis-URO-Lymphocyte-T/NK-dn_T\|URO / Disease, condition lineage and cell class	FLNB MCCC1 EZH2 UBLCP1 LIMK2 TSHZ1 PIGO	2.15e-05	200	186	7	04ea6381b93a5d8bbeda4d71c788d7fbac6d40bc
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGEF28 MUC16 CPD URB1 SRGAP3 SRGAP1 AACS	2.15e-05	200	186	7	ed093626a9cac7531a2bf02f6e345c5e84b8c060
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD16\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LILRA2 INPP5D CDH23 ADGRE2 LYST FCGR2A VCAN	2.15e-05	200	186	7	fc061de0db2e8b5ca47f5e2a1e861018e7f1b582
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGEF28 MUC16 CPD LIMK2 SRGAP3 SRGAP1 AACS	2.15e-05	200	186	7	85c0f038bcfb42669dca2b80273b0f8a1421405e
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Fibroblasts\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CCDC178 DPM1 ITPR1 SGSM2 CTNNA3 FGF14	5.19e-05	157	186	6	f086753b51860e23f1275bd75e8802d2a7d7b70a
ToppCell	3'-GW_trimst-2-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MORN1 SPTBN2 TMEM210 CYP2W1 CACTIN CLUH	5.37e-05	158	186	6	2ae863ccef201414b82a2ecf7cf1bbb1b0ce4a3c
ToppCell	E16.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SP100 MAN1A1 MARK1 PGR C2CD2L UNC119	5.76e-05	160	186	6	b2d8940ea8c068273b7da1589d3d6ae5110d8209
ToppCell	E16.5-Immune-Immune_Lymphocytic_T/NK\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SP100 MAN1A1 MARK1 PGR C2CD2L UNC119	5.76e-05	160	186	6	229841be7b984a00a301cd5d88c11226a90d8a88
ToppCell	E16.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SP100 MAN1A1 MARK1 PGR C2CD2L UNC119	5.76e-05	160	186	6	99c9ae2041445539fada842e1af01368669bfca0
ToppCell	E16.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SP100 MAN1A1 MARK1 PGR C2CD2L UNC119	5.76e-05	160	186	6	9caab1bb63c7e66c44783852ee75b16bb40fa594
ToppCell	368C-Fibroblasts-Fibroblast-E\|368C / Donor, Lineage, Cell class and subclass (all cells)	XPNPEP2 GRM7 DHRS7C RPS6KA6 C3 HELLS	6.17e-05	162	186	6	e17632778a57c71d6005d3abca3a0443a92040e7
ToppCell	368C-Fibroblasts-Fibroblast-E-\|368C / Donor, Lineage, Cell class and subclass (all cells)	XPNPEP2 GRM7 DHRS7C RPS6KA6 C3 HELLS	6.17e-05	162	186	6	ac4a80fd72c9311ea2b3e574c6284bbce4f2756c
ToppCell	droplet-Limb_Muscle-nan-3m-Myeloid-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN2 WDR81 ALS2 LIN9 UNC119 STAU2	7.06e-05	166	186	6	35db3022c33d6f8bb6587d9eec89a7cccb70271a
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH10 MUC16 AK9 GRM7 RFX3 NEK5	7.80e-05	169	186	6	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	PND10-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNB LIN9 UNC119 CNNM3 CKAP2L C4B	8.06e-05	170	186	6	7534ac69ca3a378df78d61c284e89bc96a71a4a8
ToppCell	facs-Marrow-T-cells-3m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS13C ESYT1 CYP2W1 CAMKK2 VCAN MFSD1	8.06e-05	170	186	6	a78d9789c3e7c84a36e1bd380192d7aba4a4d443
ToppCell	facs-Marrow-T-cells-3m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS13C ESYT1 CYP2W1 CAMKK2 VCAN MFSD1	8.06e-05	170	186	6	ff68600b945b3a5437b14e5411b3db800d0ccbe5
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MAN1A1 SPTBN2 PIK3C2G SRGAP3 CDH16 HELLS	8.06e-05	170	186	6	928e42c51a7079c506f21c669c4e4c1a0df84d77
ToppCell	LPS-IL1RA-Epithelial_alveolar-Mes-like-AT2_Progenitor\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZNF157 GMIP PHEX URB1 CPSF1 OAZ3	8.32e-05	171	186	6	ca2775a17b5c339c480a963953b6fa2b0731f24d
ToppCell	LPS-IL1RA-Epithelial_alveolar-Mes-like\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZNF157 GMIP PHEX URB1 CPSF1 OAZ3	8.32e-05	171	186	6	3ad4f138d9570500cfb4423a2be16bb7d1cacbf8
ToppCell	MS-CD8-proli_CD4\|MS / Condition, Cell_class and T cell subcluster	FLNB GMIP SEC61A2 SIK2 DNASE1 LRP2BP	8.59e-05	172	186	6	0b6dd257110b3f17fa71ab18a165b091a9d5ae9a
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PON1 RTKN CHST8 SRGAP3 STAU2 PRORP	9.45e-05	175	186	6	31f0fb2e47e357dbf9c15436b7df85b3c370ded7
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	XPNPEP2 CHST8 PHEX VCAN RPS6KA6 HELLS	9.75e-05	176	186	6	d30241fb8119834d6e7b59efec3f92fc7a3d1247
ToppCell	COVID-19_Mild-Lymphoid_T/NK-NK_activated\|COVID-19_Mild / Disease group, lineage and cell class	ETS1 ECPAS ADGRE2 IFIT1 SLF2 ATP5F1B	1.01e-04	177	186	6	6978a22fef40c8b455342373abe7593f5ede0fa4
ToppCell	droplet-Lung-LUNG-30m-Epithelial-Club_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD4 PON1 TRIM69 IGSF1 CFAP161 STKLD1	1.01e-04	177	186	6	092a345cb802f183322aa5542341ba2d96d4f06a
ToppCell	droplet-Lung-LUNG-30m-Epithelial-club_cell_of_bronchiole\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD4 PON1 TRIM69 IGSF1 CFAP161 STKLD1	1.01e-04	177	186	6	7ac99ff16df94b4e08d361e3d98a7b3af8d6ee3b
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR SP100 VPS13C LYST IFIT1 MIER1	1.04e-04	178	186	6	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC6A13 FARP1 LTB XYLB GREB1 ACSM2A	1.07e-04	179	186	6	58ae5a97fe2a14e1c6fdeb886397eb06fdaf0428
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCCC1 UNC119 NEK5 C3 IGSF1 CFAP161	1.10e-04	180	186	6	729f0d7af573c7796d8e28e6eec3af2fc0bd33a2
ToppCell	LPS-IL1RA-Myeloid-Neutrophils-Neutrophils\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADGRE2 CFLAR LIMK2 FCGR2A VCAN LTB	1.10e-04	180	186	6	c0c07937839652e01df10cc1e70aa005800ea6f6
ToppCell	LPS-IL1RA-Myeloid-Neutrophils\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADGRE2 CFLAR LIMK2 FCGR2A VCAN LTB	1.10e-04	180	186	6	079c199425dd3c220f03c6dca1823946f07580a1
ToppCell	COPD-Lymphoid-T_Regulatory\|World / Disease state, Lineage and Cell class	RGPD1 ETS1 ERP27 PAM LTB HELLS	1.10e-04	180	186	6	51a12fbad5fa7bb12e6d616a02ff9b5141e2b063
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCCC1 UNC119 NEK5 C3 IGSF1 CFAP161	1.10e-04	180	186	6	9ef79a7c60227e352ac166c7274adb31f585f5ca
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SGSM1 CACHD1 GTF2IRD1 ITPR1 PIK3C2G NOS1	1.14e-04	181	186	6	e0abf2707d9e0aa942c657eef7d2cbcd02f060dd
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ALS2 HMGCR PIAS1 SIK2 MAP3K9 CKAP2L	1.14e-04	181	186	6	3fe648db1cb8326066d8bde3ca1287c5c9af19bd
ToppCell	facs-Marrow-T-cells-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNB VPS13C USP25 ITPR1 SRGAP3 SP7	1.14e-04	181	186	6	7286700396676fdc41d9723979b8b408177aceb9
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	XPNPEP2 LGSN SLC6A13 XYLB GREB1 ACSM2A	1.17e-04	182	186	6	e1e58176f533092b6b974ca1ce8b02192a6e193d
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA3 GTF2IRD1 GRM7 LYST FGF14 NOS1	1.17e-04	182	186	6	a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCell	droplet-Marrow-nan-3m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS13C ESYT1 YTHDC2 SOCS6 LYST CAMKK2	1.17e-04	182	186	6	bc8d621be57f76d718d9b0f11e023b0f4dcb668d
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	XPNPEP2 LGSN SLC6A13 XYLB GREB1 ACSM2A	1.17e-04	182	186	6	57bb5a2da976464ba7c4460106bd9f692008ebd9
ToppCell	URO-Lymphocyte-T_NK-dnT\|URO / Disease, Lineage and Cell Type	FLNB MCCC1 EZH2 UBLCP1 TSHZ1 PIGO	1.17e-04	182	186	6	f2b1c524301d0f2d1b69c46f3653fd53c21c3aa0
ToppCell	droplet-Spleen-nan-18m-Lymphocytic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR SP100 MAN1A1 ETS1 LYST LTB	1.21e-04	183	186	6	28cbf909424f3be4491d49832f0aca0386560814
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ATP13A4 CDKL2 LAMA3 CACHD1 MSMO1 LRP2BP	1.21e-04	183	186	6	6847c1252d6bb105524f812658112517fd351eab
ToppCell	droplet-Lung-LUNG-30m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAH10 MORN1 TBATA NEK5 CACNA1H STKLD1	1.21e-04	183	186	6	cc844f54c7564bf432b179ca63bc7c4b9b8cfdd9
ToppCell	droplet-Spleen-nan-18m-Lymphocytic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR SP100 MAN1A1 ETS1 LYST LTB	1.21e-04	183	186	6	3fa608aa6b119869ec3280dc388dfee57160e63a
ToppCell	droplet-Lung-LUNG-30m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAH10 MORN1 TBATA NEK5 CACNA1H STKLD1	1.21e-04	183	186	6	3991830726d05cf19606d540de04093985b7bdeb
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LGSN IDO2 SLC6A13 FARP1 XYLB ACSM2A	1.24e-04	184	186	6	9434731f651820b05335085582960f08fbf895de
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MARK1 ARHGEF17 FARP1 PAM CACNA1H FGF14	1.28e-04	185	186	6	a7dba7db79275884b2a93d8a16f2e0c739e71370
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	VPS13C HMGCR LHFPL1 URB1 XYLB HELLS	1.28e-04	185	186	6	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	343B-Fibroblasts-Fibroblast-E-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	WDR81 YTHDC2 CEP192 SOCS6 PRR12 GREB1	1.28e-04	185	186	6	1b8e3ddb91797f84e4b15d2457b0c008e5be50db
ToppCell	343B-Fibroblasts-Fibroblast-E\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	WDR81 YTHDC2 CEP192 SOCS6 PRR12 GREB1	1.28e-04	185	186	6	02cbf492bc40abebaa93a3a208888afae72fbe06
ToppCell	droplet-Marrow-nan-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR VPS13C ADGRE2 LYST MIER1 CAMKK2	1.28e-04	185	186	6	7adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell	10x5'-GI_small-bowel-Myeloid_Monocytic-Nonclassical_monocytes\|GI_small-bowel / Manually curated celltypes from each tissue	LILRA2 CDH23 ADGRE2 MMEL1 SRGAP1 VCAN	1.32e-04	186	186	6	a16ecf70271894a842925f232009e2623d16947e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LGSN IDO2 SLC6A13 XYLB GREB1 ACSM2A	1.32e-04	186	186	6	a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA3 CCDC178 GTF2IRD1 GRM7 LYST NOS1	1.36e-04	187	186	6	77886f99c229610abd28c4c370d2c7d1536c9782
ToppCell	LPS-IL1RA-Myeloid-Myeloid_granulocytic\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADGRE2 LIMK2 FCGR2A VCAN LTB	1.37e-04	118	186	5	811e8521129914eef46785a4227c1860e77d9096
ToppCell	LPS-IL1RA-Myeloid-Myeloid_granulocytic-Neutrophils\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADGRE2 LIMK2 FCGR2A VCAN LTB	1.37e-04	118	186	5	6053e19d040fb394f9c270361af07b0c5a4d47db
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Non-classical_Monocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LILRA2 INPP5D CDH23 ADGRE2 LYST FCGR2A	1.40e-04	188	186	6	4e27ada1bda88811b73376c8a6136cbfc83bfdb9
ToppCell	COVID-19-kidney-DCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CCDC178 GTF2IRD1 PIK3C2G FARP1 RPS6KA6 CDH16	1.40e-04	188	186	6	1d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCell	Control-Myeloid-Monocytes\|Control / group, cell type (main and fine annotations)	INPP5D CDH23 ADGRE2 LYST FCGR2A VCAN	1.44e-04	189	186	6	3335d16bd0ffa0c1ddd06d7da645299148130c3f
ToppCell	Control-Myeloid-Transitioning_MDM\|Control / group, cell type (main and fine annotations)	INPP5D ADGRE2 FCGR2A SRGAP1 VCAN MFSD1	1.48e-04	190	186	6	d6fd8c23cde4a10cc1517b6899a5a855fdfff2e2
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CCDC178 GTF2IRD1 ITPR1 FARP1 FGF14 NOS1	1.48e-04	190	186	6	cc17ab84a9328124f146951c06be3eff9650d9fd
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MAN1A1 SPTBN2 PIK3C2G SRGAP3 CDH16 HELLS	1.48e-04	190	186	6	078f4be52fa4cc8dd9c8d7a2b6d9631c3d902285
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAN1A1 INPP5D RYR1 FCGR2A SRGAP1 MFSD1	1.48e-04	190	186	6	f573fef3762a30c38cf8fa7f45df0ffbb49dc873
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 CCDC178 ITPR1 FGF14 NOS1 DNASE1	1.48e-04	190	186	6	3dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ATP13A4 CDKL2 CACHD1 MCCC1 MSMO1 LRP2BP	1.52e-04	191	186	6	a0332a4ef629510fb313ec119195c44a3f704a80
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	VPS13C HMGCR LYST URB1 XYLB HELLS	1.52e-04	191	186	6	9454f642c3621370fa23640b631301346b300950
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLNB MAN1A1 SRGAP1 VCAN C3 IGSF1	1.57e-04	192	186	6	30cefa0990ba1f379f350bfbf994a78db145075e
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	XPNPEP2 LGSN SLC6A13 FARP1 GREB1 ACSM2A	1.57e-04	192	186	6	3e1a4cb0d83efd502c8613d41a1692bdda5860ed
ToppCell	PCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ARHGEF28 CDKL2 LAMA3 CTNNA3 MAP3K9 CKAP2L	1.57e-04	192	186	6	25378b5e4b0cea8415ff125783511fc25a56fc00
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MAN1A1 SPTBN2 PIK3C2G SRGAP3 CDH16 HELLS	1.57e-04	192	186	6	9e031bf93eb8757fdd0cc22f01b44e48f85532d5
ToppCell	NS-critical-d_0-4-Myeloid-Neutrophil\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CPD LYST CFLAR LIMK2 FCGR2A LTB	1.57e-04	192	186	6	3db74359c30172a51177e00eac1f48f483e15578
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH10 CACHD1 GRM7 NEK5 SRGAP3 FGF14	1.61e-04	193	186	6	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	10x5'-Lung-Myeloid_Monocytic\|Lung / Manually curated celltypes from each tissue	LILRA2 CDH23 ADGRE2 LYST UNC119 VCAN	1.61e-04	193	186	6	ebe6be10ef5de9e1da988e263106698d3db42fce
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH10 MORN1 MUC16 AK9 GRM7 RFX3	1.66e-04	194	186	6	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	healthy_donor-Myeloid-Monocytic-CD16+_Monocyte\|healthy_donor / Disease condition, Lineage, Cell class and subclass	LILRA2 CDH23 ADGRE2 LYST UNC119 C3	1.66e-04	194	186	6	ecf746ef1c5c4d6d9ca06a6d3e3778670b5700c2
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAN1A1 INPP5D RYR1 FCGR2A SRGAP1 MFSD1	1.66e-04	194	186	6	c95d5c4ad0210ebd672926558cc8331e6396a854
ToppCell	cellseq-Immune-Immune_Myeloid-pMON-pMON\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	LILRA2 CDH23 ADGRE2 LYST UNC119 LTB	1.70e-04	195	186	6	2cb435dae2691e1250e26e59f9b8fb652a0c383e
ToppCell	distal-1-Hematologic-Nonclassical_Monocyte\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	LILRA2 CDH23 ADGRE2 LYST UNC119 LTB	1.70e-04	195	186	6	e1a8171d1af53c2bbda758170c5053d3a3bb6ddd
ToppCell	distal-2-Hematologic-Nonclassical_Monocyte\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	LILRA2 CDH23 ADGRE2 LYST UNC119 LTB	1.70e-04	195	186	6	34bed73e4dae34b0f1076b7ff9dc7ea2096c1796
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Non-classical_Monocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LILRA2 INPP5D CDH23 ADGRE2 LYST VCAN	1.70e-04	195	186	6	10ce1b6961f10372d1f65388cbf3626a5fcd6840
ToppCell	severe_COVID-19-Non-classical_Monocyte\|World / disease group, cell group and cell class (v2)	LILRA2 CDH23 ADGRE2 UNC119 FCGR2A SRGAP1	1.70e-04	195	186	6	72928a1d987a3a5361c666f3972292aefec5f548
ToppCell	cellseq-Immune-Immune_Myeloid-pMON\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	LILRA2 CDH23 ADGRE2 LYST UNC119 LTB	1.70e-04	195	186	6	217908cb53016a6cb51f1bc3fc752c8df650df71
Drug	PHA-00767505E [723337-45-9]; Up 200; 10uM; PC3; HT_HG-U133A	MAN1A1 HMGCR SOCS6 GMIP CFLAR UNC119 LIMK2 URB1 ZNF45 PIGO	4.87e-06	196	185	10	6591_UP
Drug	Cefepime hydrochloride [123171-59-5]; Up 200; 7.4uM; MCF7; HT_HG-U133A	TPR SP100 LYST IFIT1 CHST8 CACTIN LIMK2 FARP1 CACNA1G VPS13B	5.10e-06	197	185	10	3581_UP
Drug	Alprenolol hydrochloride [13707-88-5]; Down 200; 14uM; HL60; HG-U133A	HIKESHI CPD NHLRC2 GTF2IRD1 CFLAR SLC6A13 CACTIN SLF2 EIF5B NOS1	5.33e-06	198	185	10	1571_DN
Drug	Disopyramide [3737-09-5]; Up 200; 11.8uM; MCF7; HT_HG-U133A	LAMA3 GMIP ECPAS GTF2IRD1 ARHGEF17 UNC119 CAMKK2 CELSR3 DNAH17 GREB1	5.33e-06	198	185	10	7035_UP
Drug	ikarugamycin; Down 200; 2uM; MCF7; HT_HG-U133A_EA	SP100 NHLRC2 ARHGAP35 CFLAR CACTIN LIMK2 FARP1 ZNF76 OAZ3 ZMYM4	5.57e-06	199	185	10	918_DN
Drug	hydride	HMGCR IDI2 MCCC1 NDUFS2 RYR1 CYP2W1 PARP4 MSMO1 VCAN RPS6KA6 PAM C3 C4A CACNA1H CACNA1G ACOT2 XYLB NOS1 NNT ATP5F1B	1.62e-05	835	185	20	CID000000783
Drug	Progesterone [57-83-0]; Down 200; 12.8uM; PC3; HT_HG-U133A	SP100 TBC1D9B ECPAS SEC61A2 VCAN ZNF76 XYLB NNT PIGO	2.99e-05	193	185	9	6646_DN
Drug	Hydralazine hydrochloride [304-20-1]; Down 200; 20.4uM; MCF7; HT_HG-U133A	SP100 VPS13C ARHGAP35 GRM7 ITPR1 CACTIN ANGEL2 EIF5B NOS1	3.24e-05	195	185	9	2311_DN
Drug	Chlorzoxazone [95-25-0]; Up 200; 23.6uM; MCF7; HT_HG-U133A	THSD4 MORN1 ARHGEF17 GRM7 PGR SLC6A13 SRGAP3 GREB1 VPS13B	3.37e-05	196	185	9	2263_UP
Drug	Kynurenine, 3-hydroxy (R,S) [2147-61-7]; Down 200; 17.8uM; MCF7; HT_HG-U133A	YTHDC2 ARHGAP35 ARHGEF17 CFLAR SP140L ZNF45 DNAH17 MAP3K9 NOS1	3.37e-05	196	185	9	5276_DN
Drug	Catechin-(+,-) hydrate [7295-85-4]; Up 200; 13.8uM; MCF7; HT_HG-U133A	ARHGEF28 YTHDC2 ITPR1 LIMK2 ZNF45 FARP1 ZNF76 XYLB DNASE1	3.51e-05	197	185	9	3351_UP
Drug	Naringenine [480-41-1]; Up 200; 14.6uM; MCF7; HT_HG-U133A	ARHGEF28 SPTBN2 PGR URB1 VCAN CPSF1 CACNA1H XYLB GREB1	3.65e-05	198	185	9	4422_UP
Drug	Salbutamol [18559-94-9]; Up 200; 16.8uM; MCF7; HT_HG-U133A	THSD4 ARHGEF28 YTHDC2 PGR C2CD2L LIMK2 ANGEL2 ZNF76 NNT	3.65e-05	198	185	9	4700_UP
Drug	Trolox [53188-07-1]; Up 200; 16uM; MCF7; HT_HG-U133A	ERAP1 IFIT1 CFLAR SLC6A13 URB1 ANGEL2 ZNF76 CACNA1H VPS13B	3.80e-05	199	185	9	6007_UP
Drug	Carbetapentane citrate [23142-01-0]; Down 200; 7.6uM; PC3; HT_HG-U133A	MAN1A1 YTHDC2 ARHGAP35 ITPR1 CFLAR CAMKK2 VCAN ZNF76 NNT	3.80e-05	199	185	9	4649_DN
Disease	Lupus Erythematosus, Systemic	ETS1 FCGR2A C4A C4B DNASE1 PRL	5.21e-06	71	182	6	C0024141
Disease	systemic lupus erythematosus (implicated_via_orthology)	INPP5D FCGR2A C4A C4B DNASE1	6.73e-06	43	182	5	DOID:9074 (implicated_via_orthology)
Disease	systemic lupus erythematosus (is_implicated_in)	FCGR2A C3 C4A C4B DNASE1	4.11e-05	62	182	5	DOID:9074 (is_implicated_in)
Disease	Cohen syndrome (implicated_via_orthology)	VPS13C VPS13B	1.13e-04	3	182	2	DOID:0111590 (implicated_via_orthology)
Disease	SYSTEMIC LUPUS ERYTHEMATOSUS 16	C4A DNASE1	3.74e-04	5	182	2	C3280742
Disease	Libman-Sacks Disease	ETS1 FCGR2A DNASE1 PRL	4.58e-04	58	182	4	C0242380
Disease	systemic lupus erythematosus	MAN1A1 BCL2L15 ETS1 CDH23 GTF2IRD1 LYST UBLCP1 TYK2 FCGR2A SRGAP3 CTNNA3 ZNF76 C3 C4B	4.64e-04	799	182	14	MONDO_0007915
Disease	response to cranial radiation therapy, short-term memory	CACHD1 UBLCP1 FARP1 TSHZ1	5.22e-04	60	182	4	EFO_0004335, EFO_0010950
Disease	SYSTEMIC LUPUS ERYTHEMATOSUS	FCGR2A DNASE1	5.58e-04	6	182	2	152700
Disease	Prolactinoma	CDH23 PRL	5.58e-04	6	182	2	C0033375
Disease	panic disorder	RAN USP25 GRM7	1.10e-03	33	182	3	EFO_0004262
Disease	Complement deficiency disease	C3 C4A C4B	1.10e-03	33	182	3	C0272242
Disease	X-17653 measurement	ACOT2 HELLS	1.32e-03	9	182	2	EFO_0800783
Disease	colorectal cancer	THSD4 PPP1R21 DIP2B ERAP1 NHLRC2 GRM7 PIAS1 SRGAP1 VCAN C1D NOS1	1.39e-03	604	182	11	MONDO_0005575
Disease	systemic scleroderma, rheumatoid arthritis, myositis, systemic lupus erythematosus	FLNB TYK2 PRR12	1.66e-03	38	182	3	EFO_0000685, EFO_0000717, EFO_0000783, MONDO_0007915
Disease	severe acute respiratory syndrome, COVID-19	THSD4 ARHGEF28 INPP5D CCDC178 GRM7 LYST PIK3C2G SRGAP3 SLC4A10	1.92e-03	447	182	9	EFO_0000694, MONDO_0100096
Disease	Inherited neuropathies	SPTBN2 ITPR1 FGF14	1.93e-03	40	182	3	C0598589
Disease	Systemic lupus erythematosus	FCGR2A DNASE1	2.01e-03	11	182	2	cv:C0024141
Disease	high grade glioma (is_marker_for)	CAMKK2 BRD7 HELLS	2.22e-03	42	182	3	DOID:3070 (is_marker_for)
Disease	obesity (implicated_via_orthology)	DNAH10 ITPR1 TYK2 GORASP2 C3 ATP5F1B	2.24e-03	215	182	6	DOID:9970 (implicated_via_orthology)
Disease	dementia (is_implicated_in)	PON1 HMGCR	2.40e-03	12	182	2	DOID:1307 (is_implicated_in)
Disease	cardiomyopathy (biomarker_via_orthology)	NOS1 ATP5F1B	2.82e-03	13	182	2	DOID:0050700 (biomarker_via_orthology)
Disease	hematologic cancer (implicated_via_orthology)	PIAS1 TYK2	2.82e-03	13	182	2	DOID:2531 (implicated_via_orthology)
Disease	Hyperlipoproteinemia Type IIb	PON1 HMGCR	2.82e-03	13	182	2	C1704417
Disease	Depressed mood	TYK2 TRIM69	2.82e-03	13	182	2	C0344315
Disease	pulmonary function measurement, smoking behaviour measurement, FEV/FEC ratio	THSD4 ARHGEF17 C1D	3.07e-03	47	182	3	EFO_0003892, EFO_0004713, EFO_0005671
Disease	sickle cell anemia (is_marker_for)	PON1 C3	3.28e-03	14	182	2	DOID:10923 (is_marker_for)
Disease	Endometrioma	IFIT1 PGR VCAN GREB1 PRL	3.30e-03	161	182	5	C0269102
Disease	Endometriosis	IFIT1 PGR VCAN GREB1 PRL	3.30e-03	161	182	5	C0014175
Disease	antibody measurement	THSD4 PTPN9 NEK5	3.45e-03	49	182	3	EFO_0004556
Disease	acute myeloid leukemia (is_marker_for)	EZH2 CFLAR BRD7	3.45e-03	49	182	3	DOID:9119 (is_marker_for)
Disease	Williams-Beuren syndrome (implicated_via_orthology)	GTF2IRD1 LIMK2	3.77e-03	15	182	2	DOID:1928 (implicated_via_orthology)
Disease	Hyperlipoproteinemia Type IIa	PON1 HMGCR	4.29e-03	16	182	2	C0745103
Disease	atherosclerosis (is_implicated_in)	PON1 FCGR2A	4.29e-03	16	182	2	DOID:1936 (is_implicated_in)
Disease	Kuhnt-Junius degeneration (is_implicated_in)	PON1 C3	4.84e-03	17	182	2	DOID:10873 (is_implicated_in)
Disease	Antibody Deficiency Syndrome	C3 C4A	4.84e-03	17	182	2	C0003257
Disease	non-Hodgkin lymphoma (is_implicated_in)	PON1 FCGR2A	4.84e-03	17	182	2	DOID:0060060 (is_implicated_in)
Disease	free cholesterol to total lipids in large HDL percentage	PON1 HMGCR CYP2W1	5.03e-03	56	182	3	EFO_0022279
Disease	Hypercholesterolemia, Familial	PON1 HMGCR	5.42e-03	18	182	2	C0020445
Disease	Unipolar Depression	PON1 GMIP GRM7 TYK2 SLC6A13 NOS1	5.56e-03	259	182	6	C0041696
Disease	Drug habituation	THSD4 GRM7 FARP1 CTNNA3	5.69e-03	115	182	4	C0013170
Disease	Drug abuse	THSD4 GRM7 FARP1 CTNNA3	5.69e-03	115	182	4	C0013146
Disease	Prescription Drug Abuse	THSD4 GRM7 FARP1 CTNNA3	5.69e-03	115	182	4	C4316881
Disease	Substance-Related Disorders	THSD4 GRM7 FARP1 CTNNA3	5.69e-03	115	182	4	C0236969
Disease	Drug Use Disorders	THSD4 GRM7 FARP1 CTNNA3	5.69e-03	115	182	4	C0013222
Disease	Drug Dependence	THSD4 GRM7 FARP1 CTNNA3	5.69e-03	115	182	4	C1510472
Disease	Substance Dependence	THSD4 GRM7 FARP1 CTNNA3	5.69e-03	115	182	4	C0038580
Disease	Substance Use Disorders	THSD4 GRM7 FARP1 CTNNA3	5.69e-03	115	182	4	C0038586
Disease	Organic Mental Disorders, Substance-Induced	THSD4 GRM7 FARP1 CTNNA3	5.69e-03	115	182	4	C0029231
Disease	Substance abuse problem	THSD4 GRM7 FARP1 CTNNA3	5.86e-03	116	182	4	C0740858
Disease	portal hypertension (implicated_via_orthology)	NOS1 PRL	6.04e-03	19	182	2	DOID:10762 (implicated_via_orthology)
Disease	neuroticism measurement, wellbeing measurement, depressive symptom measurement	MAN1A1 FARP1	6.04e-03	19	182	2	EFO_0007006, EFO_0007660, EFO_0007869
Disease	renovascular hypertension (biomarker_via_orthology)	NOS1 PRL	6.04e-03	19	182	2	DOID:1591 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
YEVMVHEVPGQEIEV	ESYT1	386	Q9BSJ8
DHTKPVYEDILGMQT	VCAN	2581	P13611
ELYSPQEMEVLQFHA	CTCFL	141	Q8NI51
PQEAEKYVLHMIEDG	COPS3	331	Q9UNS2
YILTVPGHLDEMQLD	C4B	251	P0C0L5
PGHLDEMQLDIQARY	C4B	256	P0C0L5
LGPSYREMHLAEQVT	BRD7	576	Q9NPI1
VVGYLPNSEHAVEAM	AACS	156	Q86V21
VHLIEDLMDPYLQHG	ALS2	1621	Q96Q42
AVLMAHYDVQEEDPV	ADGRE2	521	Q9UHX3
DHPLMTDEEYIINRA	ATP13A4	106	Q4VNC1
YRIGPSEVENALMEH	ACSM2A	471	Q08AH3
LQTPHLEFQEGETIM	FCGR2A	126	P12318
MEDRGYLVAHPTLID	CACHD1	841	Q5VU97
IGMTPTVIAVHYLDE	C3	1016	P01024
LMELSERYGPVFTVH	CYP2W1	56	Q8TAV3
EEAMNYLLSHPEVKG	ACOT2	271	P49753
MPHDIVASEDGTVYI	PAM	781	P19021
NDDPGMVDVLYAKVH	ASCC1	256	Q8N9N2
LRPMQLSVTEDGYIH	CFAP161	51	Q6P656
KAEEIGPAIQDAYMH	ADCY10	306	Q96PN6
IHLSSYVMNAEGDEP	ANGEL2	106	Q5VTE6
LIVEAYNHDLGPMRS	CDH23	1176	Q9H251
FSEMVYSQELHLPEG	DMXL1	946	Q9Y485
NPHLVSDYRVLMAEI	CFLAR	86	O15519
GNYIIIMDADLSHHP	DPM1	111	O60762
RIMDPNIVGSEHYDV	ATP5F1B	406	P06576
EVVMDPALAAQYEHD	RAN	186	P62826
VVYDEVTELQGHVLM	PIK3C2G	1396	O75747
PGPHAMTIQELVDYV	PTPN9	281	P43378
HPQDYTVENLIRMGV	LILRA2	441	Q8N149
AGPEMYEIHTNSKEE	ARHGEF28	1161	Q8N1W1
VLSPDTLQLEHMFYV	ARHGEF17	1841	Q96PE2
HLGEYVLMIRDVTTP	MORN1	431	Q5T089
GMEAEYAHPLETLIL	MSMO1	181	Q15800
MASLYVGDLHPEVTE	PABPC1L2A	1	Q5JQF8
VGDLHPEVTEAMLYE	PABPC1L2A	6	Q5JQF8
TITNLQYEEDMRHPG	MUC16	12081	Q8WXI7
TITNLKYEEDMHRPG	MUC16	12551	Q8WXI7
DIPTMLYHGTQEERQ	HELLS	296	Q9NRZ9
IYVPELGMSFQVQHE	MDN1	1846	Q9NU22
LVTHFYPLMGVELND	MDN1	3666	Q9NU22
VIFMVYPLERDVGHL	OAZ3	216	Q9UMX2
IPDYEVLSNEPHETM	LIN9	266	Q5TKA1
LMEVDPIGHLYIFAT	MAGEA3	166	P43357
LMEVDPIGHVYIFAT	MAGEA6	166	P43360
LQIETYGPHVPELEM	MNAT1	251	P51948
PHSDYIIGADTVMNE	GORASP2	131	Q9H8Y8
PDVQLTGQHMSIIYE	LAMA3	1556	Q16787
YSMLGEEIQLHFIIP	GREB1	1496	Q4ZG55
DENSPLMYHIHLVEL	ITPR1	1376	Q14643
VHYEQIFGMDELPQA	GMIP	751	Q9P107
PAELEELDHTVSMQY	LIMK2	616	P53671
LHEYFPEMQILAVSG	HMGCR	671	P04035
DHPDVVYETMRQILA	APPL1	516	Q9UKG1
MAGEEINEDYPVEIH	C1D	1	Q13901
ADIDYMNEHGPLLDS	CCDC178	261	Q5BJE1
VADPYVVIMSAEGHV	CPSF1	651	Q10570
LADMQDHAPAIGRYI	ECPAS	616	Q5VYK3
DITKTLGQMHDYVDP	IDO2	226	Q6ZQW0
VPIIMVNSVSDLHGY	MCF2L2	161	Q86YR7
HETEIMPVFQGLNEL	ERAP1	666	Q9NZ08
LLGYTPEELHAMLDV	ETS1	421	P14921
TVLHNIPYMGDEVLD	EZH2	126	Q15910
VRYAPTEVGLHEMHI	FLNB	1786	O75369
YLTPEVIQEEFSHML	NEK5	266	Q6P3R8
LEVAMYREPSLHDVG	FGF14	201	Q92915
YSGHQSVLIPPMELE	DIP2B	1216	Q9P265
HLQYERFVVAPGEDM	METTL7B	116	Q6UX53
DYDEVHDIPMIAQVT	LRP2BP	271	Q9P2M1
MVAFVVPEHQLGTAY	MFSD1	376	Q9H3U5
EEIEILMRYGQHPNI	RPS6KA6	466	Q9UK32
NYPVRGEGHSLIMVE	LHFPL1	51	Q86WI0
ELTEFGMQNVEIPHL	PARP4	131	Q9UKK3
ENASYVRPLEEGMLH	PPP1R21	306	Q6ZMI0
AMSIREQIGHPDYIL	MMEL1	501	Q495T6
EQIGHPDYILEEMNR	MMEL1	506	Q495T6
VLRYNITHPMVNDAD	NHLRC2	136	Q8NBF2
GVHQDLPLGLMDDIY	NDUFS2	231	O75306
PDMYPDEVHLTVAIV	NOS1	1186	P29475
LMSIEPDVIYAGHDN	PGR	691	P06401
LFPGDSDIDQLYHIM	CDKL2	201	Q92772
RVAHIVTGEMDSYEP	CTNNA3	546	Q9UI47
EQISPEDIVFMTIYH	IDI2	121	Q9BXS1
DLPDYESINHVVVFM	HIKESHI	26	Q53FT3
PEDEGVYICRTHIQM	IGSF1	191	Q8N6C5
EMDILQYIQDHDTPA	HS1BP3	371	Q53T59
MAVELHYEEGSPRNL	C2CD2L	401	O14523
NTLSMGIEYHEQPEE	CACNA1G	756	O43497
YGEEMPEEIHLKLQE	DNAH17	1156	Q9UFH2
VHGQLPLYGMTIEES	FARP1	801	Q9Y4F1
QLAQAISDHYPVEVM	DNASE1	266	P24855
SQHGEPLLMEYSRQE	GALT	211	P07902
RELYVMEISDNPGVH	CPD	536	O75976
PSEIEMETQIHLYGH	LYST	3601	Q99698
RQGDEVSVHYDPMIA	MCCC1	421	Q96RQ3
MNVGHEEEELKPYTE	MARK1	311	Q9P0L2
PVVEETMQDIHFHYG	IFIT1	371	P09914
ADAAPEGMAQHYLEL	MAN1A1	486	P33908
HLEAYFEQLAIPGMI	CEP192	226	Q8TEP8
IEINSLHMVTEYNPV	ERP27	136	Q96DN0
LVEVLDDPNEDHLYM	CAMKK2	251	Q96RR4
DHLYMVFELVNQGPV	CAMKK2	261	Q96RR4
EMYAPHSIRIEGDVT	GRM7	36	Q14831
DLAVEMHEPYTFLNG	CACTIN	321	Q8WUQ7
YGVHPVEVAEEVMRT	DHRS7C	251	A6NNS2
HIMYQIVEGNIPELF	CELSR3	1101	Q9NYQ7
SRYAEALGLDHMVPV	GTF2IRD1	361	Q9UHL9
NTLSMGVEYHEQPEE	CACNA1H	806	O95180
MALHEGEPRIYEDIQ	DNAH10	2736	Q8IVF4
SYGENIDEELKTHPM	RYR1	2776	P21817
RGMNYLHDEAIVPII	MAP3K9	251	P80192
YAAPLELHVLVMDEN	CDH16	316	O75309
YILTVPGHLDEMQLD	C4A	251	P0C0L4
PGHLDEMQLDIQARY	C4A	256	P0C0L4
DQPFMQELVDGLYHT	LGSN	236	Q5TDP6
NLHPGVTDYMDRLLD	MIER1	351	Q8N108
QSELYVRPDDVHMNI	RGPD1	146	P0DJD0
QEYVDIMEELLGSHP	NUTM2F	396	A1L443
QEYVDIMEELLGSHP	NUTM2G	381	Q5VZR2
GVPYDIVLEMDEINH	NNT	981	Q13423
EPLYHLVTEVRGMQE	PRL	121	P01236
QGSLYHEMAIEPLDD	RTKN	446	Q9BST9
TLEEVMAEHNPQYLI	AK9	251	Q5TCS8
VDNLAVVMGLHPDYF	SESN2	76	P58004
NDEVLPVMYIHRQSA	SNIP1	266	Q8TAD8
LVPHQYIVVQDMDDT	SRGAP1	791	Q7Z6B7
MGAIFEDPVHVVVYI	SEC61A2	351	Q9H9S3
TDEDNAMYLLVVNHP	PON1	121	P27169
CDHGMYQALVEILIP	RFX3	431	P48380
ASVMLEHDPQYAVIL	EIF5B	1021	O60841
EDMEAVPGYLSLHQS	SGSM2	271	O43147
QAPIMLLSGHEGEVY	SNRNP40	56	Q96DI7
MGLVTHLQYPVPLEE	INPP5D	91	Q92835
MLDAVDPQHNGYVLV	SIK2	911	Q9H0K1
EKPEYIGEAQVLQMH	TBATA	321	Q96M53
IYNVEPLMEKGHLDH	WDR45	31	Q9Y484
SIHPEGYQDREIMLL	SLF2	926	Q8IX21
APYEHLIIDGLFMEI	PIAS1	381	O75925
MIQALEDTHDELYLP	PRR12	1866	Q9ULL5
FSEVNMQEYPDLIHI	SP140L	126	Q9H930
LYQELLGHDIVPMLE	PRORP	266	O15091
LMDTVPAEQLYEAHL	ARHGAP35	406	Q9NRY4
EALQELHPYMEGAQL	URB1	1106	O60287
LHPYMEGAQLREVTL	URB1	1111	O60287
DPMEQDLYHAIATVA	TBC1D9B	1041	Q66K14
EYMAHIAPEVVGQVA	BCL2L15	121	Q5TBC7
EYEMSIAAHLVDPLN	ATAD1	71	Q8NBU5
FVQYLLDVHRPVGMD	CHST8	311	Q9H2A9
AVSRYPEMLQEHDLV	CKAP2L	696	Q8IYA6
IMQSGHTRIPVYEEE	CNNM3	341	Q8NE01
ERVMGTEHPNTIQEY	CLUH	1051	O75153
GMSHEEDQLIPNLYR	PRPF8	1356	Q6P2Q9
IDPGDYVEMNDSITH	TRIM69	11	Q86WT6
GVQEDLMDLHPVYVE	TMEM210	91	A6NLX4
GDRMEIIELANHPYF	CTPS2	506	Q9NRF8
LIEHQRMHSGEKPYE	ZNF157	401	P51786
EGLNHIMPRDDIFVY	USP4	551	Q13107
EELISEMIRHPYETQ	UNC119	201	Q13432
VPLHVAYAVGEDDLM	MRPL38	171	Q96DV4
QEYVLSHTEMPGTLQ	SPTBN2	1191	O15020
GILHLSPDVYQEMEA	STAU2	411	Q9NUL3
GLIPHQYIVVQDMDD	SRGAP3	791	O43295
SHPRALMEIYEEINV	TIGD1	306	Q96MW7
EDPVHAVVYIVFMLG	SEC61A1	356	P61619
MLLVHLASYEEILPE	STKLD1	616	Q8NE28
LEEEVHYGSSPLAML	SP7	6	Q8TDD2
LGMYETPLFLAHEEE	TPR	2191	P12270
ELSEAYPINMHNDLE	SLC4A10	646	Q6U841
ESLVTALVDMYPHVF	SLC6A13	396	Q9NSD5
FSDVNMQEYPDLIHI	SP100	126	P23497
MTHVYEDLRGQIAIP	ZNRF4	196	Q8WWF5
YFDVMEITPEIIGRH	XYLB	376	O75191
SYLGQEMEPHLQEKL	USP25	991	Q9UHP3
VGYPEFIMNDTHVNE	PHEX	476	P78562
EHYSLPPVIDKMNIE	VPS13C	1796	Q709C8
MEAVPGYLSLHQTAD	SGSM1	271	Q2NKQ1
TYQLAHGTAEEKMPV	TTLL12	176	Q14166
VAGMYPNLVHVDREN	YTHDC2	976	Q9H6S0
DETRIDMQYPAQHKG	VPS13B	316	Q7Z7G8
ETGVELMRPYLHEFL	UBLCP1	156	Q8WVY7
TVDNGILEHLYPTMD	PIGO	206	Q8TEQ8
LSAYIIPGTDAHMNE	XPNPEP2	66	O43895
TYHMPDVELLQDVGN	TRIM64C	236	A6NLI5
EGPTNEILDVYMIHQ	THSD4	501	Q6ZMP0
PVALEDVYPIHMILE	GTF3C1	91	Q12789
ETMVYHPNIDLEGNV	UBE2M	96	P61081
METLQEVGLRYLPHE	ZNF45	86	Q02386
DEHVPVVIGLMPQDY	SOCS6	206	O14544
YIMSDLGPQERVHIS	TSHZ1	916	Q6ZSZ6
AEALLESPEMLYVVH	WDR81	221	Q562E7
LPNGYMFSRIEEEHL	ZMYM4	1351	Q5VZL5
PVQLEDGSMAYIHRT	ZNF76	61	P36508
PENIMVTEYVEHGPL	TYK2	681	P29597
GERVYVNISHPDMVD	LTB	216	Q06643