Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionaliphatic amine oxidase activity

AOC2 AOC3

5.85e-054632GO:0052595
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

JAK1 NEK3 PIK3C2G PIK3CB PPM1D ETNK2 FES MAP3K10 MAP3K21 ALK

6.97e-057096310GO:0016773
GeneOntologyMolecularFunctionkinase activity

JAK1 NEK3 PIK3C2G PIK3CB PPM1D ETNK2 FES MAP3K10 MAP3K21 ALK

1.29e-047646310GO:0016301
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

JAK1 NEK3 RPAP1 PIK3C2G PIK3CB PPM1D ETNK2 FES MAP3K10 MAP3K21 ALK

1.52e-049386311GO:0016772
GeneOntologyMolecularFunction1-phosphatidylinositol-4-phosphate 3-kinase activity

PIK3C2G PIK3CB

2.04e-047632GO:0035005
GeneOntologyMolecularFunctionprimary methylamine oxidase activity

AOC2 AOC3

3.48e-049632GO:0008131
GeneOntologyMolecularFunction1-phosphatidylinositol-3-kinase activity

PIK3C2G PIK3CB

5.29e-0411632GO:0016303
GeneOntologyMolecularFunctionprotein kinase activity

JAK1 NEK3 PIK3CB PPM1D FES MAP3K10 MAP3K21 ALK

5.73e-04600638GO:0004672
GeneOntologyMolecularFunctionJUN kinase kinase kinase activity

MAP3K10 MAP3K21

6.34e-0412632GO:0004706
GeneOntologyMolecularFunctionN6-methyladenosine-containing RNA reader activity

IGF2BP3 IGF2BP2

1.00e-0315632GO:1990247
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor

AOC2 AOC3

1.14e-0316632GO:0016641
GeneOntologyMolecularFunctionquinone binding

AOC2 AOC3

1.29e-0317632GO:0048038
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-NH2 group of donors

AOC2 AOC3

1.79e-0320632GO:0016638
DomainSer-Thr/Tyr_kinase_cat_dom

JAK1 NEK3 FES MAP3K10 MAP3K21 ALK

6.38e-06138626IPR001245
Domain-

AOC2 AOC3

3.25e-0536222.70.98.20
DomainCu_amine_oxidase_N3

AOC2 AOC3

3.25e-053622IPR015802
DomainCu_amine_oxidase_N2

AOC2 AOC3

3.25e-053622IPR015800
DomainCu_amine_oxidN2

AOC2 AOC3

3.25e-053622PF02727
DomainCu_amine_oxidN3

AOC2 AOC3

3.25e-053622PF02728
DomainCu_amine_oxidase_N-reg

AOC2 AOC3

3.25e-053622IPR016182
DomainCu_amine_oxid

AOC2 AOC3

3.25e-053622PF01179
DomainCu_amine_oxidase_C

AOC2 AOC3

3.25e-053622IPR015798
DomainCOPPER_AMINE_OXID_1

AOC2 AOC3

3.25e-053622PS01164
DomainCOPPER_AMINE_OXID_2

AOC2 AOC3

3.25e-053622PS01165
DomainMLK1/MLK2/MLK4

MAP3K10 MAP3K21

6.48e-054622IPR016231
DomainMAP3K10

MAP3K10 MAP3K21

6.48e-054622IPR015785
DomainCu_amine_oxidase

AOC2 AOC3

6.48e-054622IPR000269
DomainPkinase_Tyr

JAK1 FES MAP3K10 MAP3K21 ALK

6.86e-05129625PF07714
DomainKinase-like_dom

JAK1 NEK3 PIK3C2G PIK3CB ETNK2 FES MAP3K10 MAP3K21 ALK

7.04e-05542629IPR011009
DomainTyrKc

JAK1 FES MAP3K21 ALK

2.08e-0488624SM00219
DomainTyr_kinase_cat_dom

JAK1 FES MAP3K21 ALK

2.08e-0488624IPR020635
DomainPI3K_Ras-bd_dom

PIK3C2G PIK3CB

2.25e-047622IPR000341
DomainPI3K_rbd

PIK3C2G PIK3CB

2.25e-047622PF00794
DomainPI3K_RBD

PIK3C2G PIK3CB

2.25e-047622PS51546
DomainPI3K_rbd

PIK3C2G PIK3CB

2.25e-047622SM00144
DomainPI3K_C2_dom

PIK3C2G PIK3CB

3.00e-048622IPR002420
DomainPI3K_C2

PIK3C2G PIK3CB

3.00e-048622PF00792
DomainPI3K_C2

PIK3C2G PIK3CB

3.00e-048622PS51547
DomainPI3K_C2

PIK3C2G PIK3CB

3.00e-048622SM00142
DomainPI3Ka

PIK3C2G PIK3CB

3.85e-049622PF00613
Domain-

PIK3C2G PIK3CB

3.85e-0496221.25.40.70
DomainPI3Ka

PIK3C2G PIK3CB

3.85e-049622SM00145
DomainPIK_HELICAL

PIK3C2G PIK3CB

4.80e-0410622PS51545
DomainPI_Kinase

PIK3C2G PIK3CB

4.80e-0410622IPR015433
DomainPInositide-3_kin_accessory_dom

PIK3C2G PIK3CB

4.80e-0410622IPR001263
DomainPI3/4_kinase_CS

PIK3C2G PIK3CB

1.11e-0315622IPR018936
Domain-

PIK3C2G PIK3CB

1.26e-03166221.10.1070.11
DomainPI3Kc

PIK3C2G PIK3CB

1.26e-0316622SM00146
Domain-

PIK3C2G PIK3CB SYT1 NEDD4

1.48e-031486242.60.40.150
DomainProtein_kinase_ATP_BS

JAK1 NEK3 FES MAP3K10 MAP3K21 ALK

1.58e-03379626IPR017441
DomainPI3/4_kinase_cat_dom

PIK3C2G PIK3CB

1.60e-0318622IPR000403
DomainPI3_PI4_kinase

PIK3C2G PIK3CB

1.60e-0318622PF00454
DomainPI3_4_KINASE_3

PIK3C2G PIK3CB

1.60e-0318622PS50290
DomainPI3_4_KINASE_1

PIK3C2G PIK3CB

1.60e-0318622PS00915
DomainPI3_4_KINASE_2

PIK3C2G PIK3CB

1.60e-0318622PS00916
DomainC2_dom

PIK3C2G PIK3CB SYT1 NEDD4

2.15e-03164624IPR000008
DomainPROTEIN_KINASE_ATP

JAK1 NEK3 FES MAP3K10 MAP3K21 ALK

4.10e-03459626PS00107
DomainPROTEIN_KINASE_TYR

JAK1 FES ALK

4.11e-0397623PS00109
DomainTyr_kinase_AS

JAK1 FES ALK

4.11e-0397623IPR008266
DomainProt_kinase_dom

JAK1 NEK3 FES MAP3K10 MAP3K21 ALK

5.56e-03489626IPR000719
DomainPROTEIN_KINASE_DOM

JAK1 NEK3 FES MAP3K10 MAP3K21 ALK

5.79e-03493626PS50011
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

CRYBG2 ERCC2 PDE4A MAN2B1 RPAP1 CCDC34 AOC2 SEC16A PEX6 PCNX1 GGA1 CRAMP1 IGSF3

7.52e-081105631335748872
Pubmed

A network of heterochronic genes including Imp1 regulates temporal changes in stem cell properties.

IGF2BP3 IGF2BP2 APC SYT1

3.38e-073263424192035
Pubmed

Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders.

IGF2BP3 IGF2BP2 ZMYND8 APC

1.14e-064363436950384
Pubmed

Genomic analysis of mouse retinal development.

CLIP3 RAB3GAP1 IGF2BP3 ERCC2 CHST14 PIK3C2G SCG2 APC SYT1 RPL15 NEDD4

1.75e-061006631115226823
Pubmed

Associations of schizophrenia risk genes ZNF804A and CACNA1C with schizotypy and modulation of attention in healthy subjects.

CACNA1C ZNF804A

3.23e-06263231076262
Pubmed

The impact of CACNA1C gene, and its epistasis with ZNF804A, on white matter microstructure in health, schizophrenia and bipolar disorder1.

CACNA1C ZNF804A

3.23e-06263227790829
Pubmed

GGA function is required for maturation of neuroendocrine secretory granules.

SCG2 GGA1

3.23e-06263216601685
Pubmed

Impact of ZNF804A rs1344706 or CACNA1C rs1006737 polymorphisms on cognition in patients with severe mental disorders: A systematic review and meta-analysis.

CACNA1C ZNF804A

3.23e-06263235786202
Pubmed

The unique substrate specificity of human AOC2, a semicarbazide-sensitive amine oxidase.

AOC2 AOC3

3.23e-06263219588076
Pubmed

Neuronal precursor cell-expressed developmentally down-regulated 4-1 (NEDD4-1) controls the sorting of newly synthesized Ca(V)1.2 calcium channels.

CACNA1C NEDD4

3.23e-06263221220429
Pubmed

Anatomical distribution of primary amine oxidase activity in four adipose depots and plasma of severely obese women with or without a dysmetabolic profile.

AOC2 AOC3

3.23e-06263227766585
Pubmed

The effect of psychosis associated CACNA1C, and its epistasis with ZNF804A, on brain function.

CACNA1C ZNF804A

3.23e-06263230079586
Pubmed

A functional neuroimaging association study on the interplay between two schizophrenia genome-wide associated genes (CACNA1C and ZNF804A).

CACNA1C ZNF804A

3.23e-06263235796825
Pubmed

Intestinal knockout of Nedd4 enhances growth of Apcmin tumors.

APC NEDD4

3.23e-06263227086928
Pubmed

HIV-1 Tat protein induces the production of IDO in human monocyte derived-dendritic cells through a direct mechanism: effect on T cells proliferation.

JAK1 PIK3C2G PIK3CB

5.38e-061963324073214
Pubmed

IGF2BP1, IGF2BP2 and IGF2BP3 genotype, haplotype and genetic model studies in metabolic syndrome traits and diabetes.

IGF2BP3 IGF2BP2

9.68e-06363220627640
Pubmed

Expression of the RNA-binding protein VICKZ in normal hematopoietic tissues and neoplasms.

IGF2BP3 IGF2BP2

9.68e-06363217296566
Pubmed

Hematopoietic prostaglandin D synthase suppresses intestinal adenomas in ApcMin/+ mice.

HPGDS APC

9.68e-06363217283118
Pubmed

Fes mediates the IL-4 activation of insulin receptor substrate-2 and cellular proliferation.

JAK1 FES

9.68e-06363211160325
Pubmed

IMP2 and IMP3 cooperate to promote the metastasis of triple-negative breast cancer through destabilization of progesterone receptor.

IGF2BP3 IGF2BP2

9.68e-06363229217458
Pubmed

Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation.

IGF2BP3 IGF2BP2

9.68e-06363229476152
Pubmed

Expression of IGF-II mRNA-binding proteins (IMPs) in gonads and testicular cancer.

IGF2BP3 IGF2BP2

9.68e-06363216049158
Pubmed

A family of insulin-like growth factor II mRNA-binding proteins represses translation in late development.

IGF2BP3 IGF2BP2

9.68e-0636329891060
Pubmed

m6A-dependent upregulation of DDX21 by super-enhancer-driven IGF2BP2 and IGF2BP3 facilitates progression of acute myeloid leukaemia.

IGF2BP3 IGF2BP2

9.68e-06363238572589
Pubmed

VICKZ proteins: a multi-talented family of regulatory RNA-binding proteins.

IGF2BP3 IGF2BP2

9.68e-06363215601260
Pubmed

Initiation of stress granule assembly by rapid clustering of IGF2BP proteins upon osmotic shock.

IGF2BP3 IGF2BP2

9.68e-06363232668274
Pubmed

Wip1 phosphatase regulates p53-dependent apoptosis of stem cells and tumorigenesis in the mouse intestine.

PPM1D APC

9.68e-06363218371349
Pubmed

Characterization of AOC2 gene encoding a copper-binding amine oxidase expressed specifically in retina.

AOC2 AOC3

9.68e-06363214585497
Pubmed

ZBP1 recognition of beta-actin zipcode induces RNA looping.

IGF2BP3 IGF2BP2

9.68e-06363220080952
Pubmed

ANK3, CACNA1C and ZNF804A gene variants in bipolar disorders and psychosis subphenotype.

CACNA1C ZNF804A

9.68e-06363221767209
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

IGF2BP3 CD5 STON1 SEC16A APC MRPS9 GGA1 IGSF3 RPL15

1.07e-0577763935844135
Pubmed

HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway.

PDE4A PIK3C2G PIK3CB

1.61e-052763311156964
Pubmed

The RNA Binding Protein IMP2 Preserves Glioblastoma Stem Cells by Preventing let-7 Target Gene Silencing.

IGF2BP3 IGF2BP2

1.93e-05463227184842
Pubmed

Kir5.1 regulates Nedd4-2-mediated ubiquitination of Kir4.1 in distal nephron.

KCNJ16 NEDD4

1.93e-05463229897283
Pubmed

H19 RNA binds four molecules of insulin-like growth factor II mRNA-binding protein.

IGF2BP3 IGF2BP2

1.93e-05463210875929
Pubmed

The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability.

ZMYND8 APC

1.93e-05463233932349
Pubmed

Phosphodiesterase 4B in the cardiac L-type Ca²⁺ channel complex regulates Ca²⁺ current and protects against ventricular arrhythmias in mice.

CACNA1C PDE4A

1.93e-05463221670503
Pubmed

Truncated PPM1D impairs stem cell response to genotoxic stress and promotes growth of APC-deficient tumors in the mouse colon.

PPM1D APC

1.93e-05463231659152
Pubmed

mTOR phosphorylates IMP2 to promote IGF2 mRNA translation by internal ribosomal entry.

IGF2BP3 IGF2BP2

1.93e-05463221576258
Pubmed

Differential regulation of the insulin-like growth factor II mRNA-binding protein genes by architectural transcription factor HMGA2.

IGF2BP3 IGF2BP2

1.93e-05463215225648
Pubmed

miR-1275: A single microRNA that targets the three IGF2-mRNA-binding proteins hindering tumor growth in hepatocellular carcinoma.

IGF2BP3 IGF2BP2

1.93e-05463226160756
Pubmed

IMP2 axonal localization, RNA interactome, and function in the development of axon trajectories.

IGF2BP3 IGF2BP2

1.93e-05463227385015
Pubmed

Functional dissection of the interactions of stonin 2 with the adaptor complex AP-2 and synaptotagmin.

STON1 SYT1

1.93e-05463214726597
Pubmed

Human stoned B interacts with AP-2 and synaptotagmin and facilitates clathrin-coated vesicle uncoating.

STON1 SYT1

3.22e-05563211454741
Pubmed

Multiple modification and protein interaction signals drive the Ring finger protein 11 (RNF11) E3 ligase to the endosomal compartment.

GGA1 NEDD4

4.82e-05663220676133
Pubmed

Direct interaction of the Rab3 effector RIM with Ca2+ channels, SNAP-25, and synaptotagmin.

CACNA1C SYT1

4.82e-05663211438518
Pubmed

circNDUFB2 inhibits non-small cell lung cancer progression via destabilizing IGF2BPs and activating anti-tumor immunity.

IGF2BP3 IGF2BP2

4.82e-05663233436560
Pubmed

The application of the polymerase chain reaction to cloning members of the protein tyrosine kinase family.

JAK1 FES

6.74e-0576322482828
Pubmed

IL-4/IL-13 signaling beyond JAK/STAT.

JAK1 FES

6.74e-05763210856136
Pubmed

Stonin 2: an adaptor-like protein that interacts with components of the endocytic machinery.

STON1 SYT1

8.98e-05863211381094
Pubmed

METTL16 promotes glycolytic metabolism reprogramming and colorectal cancer progression.

IGF2BP3 IGF2BP2

1.15e-04963237340443
Pubmed

Role of Gadd45a in Wip1-dependent regulation of intestinal tumorigenesis.

PPM1D APC

1.15e-04963222555459
Pubmed

The HIV-1 nef protein interferes with phosphatidylinositol 3-kinase activation 1.

PIK3C2G PIK3CB

1.44e-04106328636073
Pubmed

Extracellular human immunodeficiency virus type-1 Tat protein activates phosphatidylinositol 3-kinase in PC12 neuronal cells.

PIK3C2G PIK3CB

1.44e-04106328798481
Pubmed

CAPS1 regulates catecholamine loading of large dense-core vesicles.

SCG2 SYT1

1.44e-041063215820695
Pubmed

Expression of HIV-1 nef decreases basal phosphatidyl-inositol 3-kinase activity.

PIK3C2G PIK3CB

1.44e-04106329247029
Pubmed

Two dominant host resistance genes to pre-B lymphoma in wild-derived inbred mouse strain MSM/Ms.

APC CFB

1.44e-04106328706013
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

RPAP1 PCDH11X CRAMP1 DNAH1

1.75e-0415363410718198
Pubmed

HIV-1 gp120-induced TNF-{alpha} production by primary human macrophages is mediated by phosphatidylinositol-3 (PI-3) kinase and mitogen-activated protein (MAP) kinase pathways.

PIK3C2G PIK3CB

1.76e-041163216081599
Pubmed

HIV-1 Tat induces tyrosine phosphorylation of p125FAK and its association with phosphoinositide 3-kinase in PC12 cells.

PIK3C2G PIK3CB

1.76e-04116329708406
Pubmed

HIV-Nef enhances interleukin-2 production and phosphatidylinositol 3-kinase activity in a human T cell line.

PIK3C2G PIK3CB

1.76e-041163210985305
Pubmed

Nef-mediated disruption of HLA-A2 transport to the cell surface in T cells.

PIK3C2G PIK3CB

1.76e-041163212584329
Pubmed

Ligands of CD4 inhibit the association of phospholipase Cgamma1 with phosphoinositide 3 kinase in T cells: regulation of this association by the phosphoinositide 3 kinase activity.

PIK3C2G PIK3CB

1.76e-04116329808187
Pubmed

Cold-inducible RBM3 inhibits PERK phosphorylation through cooperation with NF90 to protect cells from endoplasmic reticulum stress.

IGF2BP3 IGF2BP2 MRPS9

1.80e-046063326472337
Pubmed

Human immunodeficiency virus type 1 tat-mediated cytotoxicity of human brain microvascular endothelial cells.

PIK3C2G PIK3CB

2.11e-041263214602571
Pubmed

Colony-stimulating factor-1 requires PI3-kinase-mediated metabolism for proliferation and survival in myeloid cells.

PIK3C2G PIK3CB

2.11e-041263216514418
Pubmed

HIV-1 Nef plays an essential role in two independent processes in CD4 down-regulation: dissociation of the CD4-p56(lck) complex and targeting of CD4 to lysosomes.

PIK3C2G PIK3CB

2.11e-041263210208934
Pubmed

Recruitment of phosphatidylinositol 3-kinase to CD28 inhibits HIV transcription by a Tat-dependent mechanism.

PIK3C2G PIK3CB

2.11e-041263212077252
Pubmed

Down-regulation of LFA-1-mediated T cell adhesion induced by the HIV envelope glycoprotein gp160 requires phosphatidylinositol-3-kinase activity.

PIK3C2G PIK3CB

2.11e-04126329341793
Pubmed

Phosphatidylinositol 3-kinase regulates human immunodeficiency virus type 1 replication following viral entry in primary CD4+ T lymphocytes and macrophages.

PIK3C2G PIK3CB

2.11e-041263212551992
Pubmed

HIV-1 Nef in macrophage-mediated disease pathogenesis.

PIK3C2G PIK3CB

2.49e-041363223215766
Pubmed

Genotype phenotype correlations in Israeli colorectal cancer patients.

ERCC2 APC

2.49e-041363215523694
Pubmed

Extracellular HIV-1 Tat protein activates phosphatidylinositol 3- and Akt/PKB kinases in CD4+ T lymphoblastoid Jurkat cells.

PIK3C2G PIK3CB

2.49e-04136329394803
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

RAB3GAP1 IGF2BP3 ERCC2 IGF2BP2 RPAP1 ZMYND8 MRPS9

2.80e-0470463729955894
Pubmed

Neurocalcin Delta Knockout Impairs Adult Neurogenesis Whereas Half Reduction Is Not Pathological.

APC MAP3K10

2.90e-041463230853885
Pubmed

Infection of human immunodeficiency virus and intracellular viral Tat protein exert a pro-survival effect in a human microglial cell line.

PIK3C2G PIK3CB

2.90e-041463217157319
Pubmed

HIV Nef enhances Tat-mediated viral transcription through a hnRNP-K-nucleated signaling complex.

PIK3C2G PIK3CB

3.34e-041563218854243
Pubmed

Zbtb7b engages the long noncoding RNA Blnc1 to drive brown and beige fat development and thermogenesis.

JAK1 NEDD4

3.34e-041563228784777
Pubmed

HIV-1 gp120-mediated apoptosis of T cells is regulated by the membrane tyrosine phosphatase CD45.

PIK3C2G PIK3CB

3.81e-041663216524887
Pubmed

HIV-1 Nef blocks transport of MHC class I molecules to the cell surface via a PI 3-kinase-dependent pathway.

PIK3C2G PIK3CB

3.81e-041663211289809
Pubmed

Human immunodeficiency virus type 1 Tat accelerates Kaposi sarcoma-associated herpesvirus Kaposin A-mediated tumorigenesis of transformed fibroblasts in vitro as well as in nude and immunocompetent mice.

PIK3C2G PIK3CB

3.81e-041663220019835
Pubmed

Akt/Nox2/NF-κB signaling pathway is involved in Tat-induced HIV-1 long terminal repeat (LTR) transactivation.

PIK3C2G PIK3CB

3.81e-041663221029719
Pubmed

A high-throughput candidate gene mutation screen in lymphoproliferative and myeloproliferative neoplasias.

JAK1 FES

3.81e-041663219464057
Pubmed

Erythropoietin plus insulin-like growth factor-I protects against neuronal damage in a murine model of human immunodeficiency virus-associated neurocognitive disorders.

PIK3C2G PIK3CB

3.81e-041663220818790
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

JAK1 CRNKL1 PPM1D ZMYND8 PARL

3.88e-0434163532971831
Pubmed

Synergistic cooperation between methamphetamine and HIV-1 gsp120 through the P13K/Akt pathway induces IL-6 but not IL-8 expression in astrocytes.

PIK3C2G PIK3CB

4.32e-041763223251686
Pubmed

Macrophage activation through CCR5- and CXCR4-mediated gp120-elicited signaling pathways.

PIK3C2G PIK3CB

4.32e-041763212960231
Pubmed

Signaling mechanism of HIV-1 gp120 and virion-induced IL-1beta release in primary human macrophages.

PIK3C2G PIK3CB

4.32e-041763218453587
Pubmed

Mapping of five subtype genes for muscarinic acetylcholine receptor to mouse chromosomes.

CD5 CHRM5

4.32e-041763210549128
Pubmed

SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes.

JAK1 IGF2BP3 SEC16A APC RPL15

4.54e-0435363527545878
Pubmed

The protein tyrosine kinase family of the human genome.

JAK1 FES ALK

4.69e-048363311114734
Pubmed

HIV-1 Nef downregulates MHC-I by a PACS-1- and PI3K-regulated ARF6 endocytic pathway.

PIK3C2G PIK3CB

4.85e-041863212526811
Pubmed

Genetically distinct subsets within ANCA-associated vasculitis.

MXRA5 PCDH11X

4.85e-041863222808956
Pubmed

EBP1 is a nucleolar growth-regulating protein that is part of pre-ribosomal ribonucleoprotein complexes.

IGF2BP2 RPL15

4.85e-041863215064750
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

JAK1 CRNKL1 SCG2 ZMYND8 APC MRPS9 MAP3K10 GEN1 RPL15

4.90e-04128563935914814
Pubmed

Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays.

AMPD2 FES SYT1 NEDD4

5.13e-0420363419953087
Pubmed

No evidence for association between 19 cholinergic genes and bipolar disorder.

CHRM5 CHRNB1

5.41e-041963217373692
Pubmed

Large-scale concatenation cDNA sequencing.

CACNA1C AOC3 PCDH11X APC ZNF804A RPL15

5.71e-045686369110174
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

IGF2BP3 STON1 SEC16A APC

5.72e-0420963436779422
Pubmed

Extracellular HIV-1 Tat protein induces a rapid and selective activation of protein kinase C (PKC)-alpha, and -epsilon and -zeta isoforms in PC12 cells.

PIK3C2G PIK3CB

6.63e-04216329446795
CytobandEnsembl 112 genes in cytogenetic band chr15q15

RPAP1 CHST14 RHOV

1.11e-03147633chr15q15
Cytoband15q15.1

RPAP1 CHST14

1.93e-034763215q15.1
Cytoband3p21.3

VILL DLEC1

3.02e-03596323p21.3
Cytoband17q21

AOC2 AOC3

3.43e-036363217q21
GeneFamilyPhosphatidylinositol 3-kinase subunits

PIK3C2G PIK3CB

1.68e-048452831
GeneFamilyMitogen-activated protein kinase kinase kinases|RAF family

MAP3K10 MAP3K21

1.61e-0324452654
ToppCellwk_15-18-Epithelial-PNS-KCNIP4+_neuron|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

GPR22 SCG2 SYT1 ZNF804A ALK

5.50e-06179635e20bfdfb6d5af8556eb66b81a19fbe4e3e28334a
ToppCellwk_15-18-Epithelial-PNS-SST+_neuron|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

GPR22 SCG2 SYT1 ZNF804A ALK

5.96e-06182635a7e77aaaddabf78c7784f72b3431703fc5ee4a8c
ToppCellwk_15-18-Epithelial-PNS-PCP4+_neuron|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

GPR22 SCG2 SYT1 ZNF804A ALK

7.16e-0618963522c927d2691b867fbdee1fbee042a6d3f7eadd7d
ToppCellwk_08-11-Epithelial-PNS-SST+_neuron|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

GPR22 SCG2 SYT1 ZNF804A ALK

7.53e-06191635df2bef74a54f4c23c99bd3b93225fd36bcd90723
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR22 SCG2 SYT1 ZNF804A ALK

7.53e-0619163573b15ffa60d592c43aaa575f1b1479d49a66dfe8
ToppCellwk_08-11-Epithelial-PNS-KCNIP4+_neuron|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

GPR22 SCG2 SYT1 ZNF804A ALK

7.72e-0619263553642c88891f4e4e14b1740c5ced759b7d8b3572
ToppCellwk_15-18-Epithelial-PNS|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

GPR22 SCG2 SYT1 ZNF804A ALK

7.92e-06193635ca65f8f93058ad50d89e69e06c10deeb46dbfc87
ToppCellThalamus-Neuronal|Thalamus / BrainAtlas - Mouse McCarroll V32

RAB3GAP1 GPR22 RHOV SCG2 SYT1

7.92e-06193635712a4acd1167e43543950bc819ff11984e6f718d
ToppCell18-Airway-Epithelial-Epithelial|Airway / Age, Tissue, Lineage and Cell class

GPR22 SCG2 SYT1 ZNF804A ALK

8.12e-06194635d3c90e1f1228f8ba0ba56105c6cf4f302c388f28
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR22 SCG2 SYT1 ZNF804A ALK

8.75e-06197635a1ae1aa797762a3768e14434c7e5cd19c595ecb3
ToppCellwk_08-11-Epithelial-PNS|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

GPR22 SCG2 SYT1 ZNF804A ALK

8.75e-06197635ce3f9feb6935f0e9daf13673b0a0d6e92817e187
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR22 SCG2 SYT1 ZNF804A ALK

8.75e-061976355593721407f61fc5bc3f2f8bf8fa2604c4e29565
ToppCellControl_saline-Epithelial_airway|Control_saline / Treatment groups by lineage, cell group, cell type

CRYBG2 IQCH VILL DLEC1 DNAH1

8.97e-06198635e6863238e022ecfb6a8e3f4b7661b376e92c5d8f
ToppCellControl_saline-Epithelial_airway-airway_epithelial|Control_saline / Treatment groups by lineage, cell group, cell type

CRYBG2 IQCH VILL DLEC1 DNAH1

8.97e-06198635e7aa42e5fbd42c68f50cda4a8f3aa464c862c007
ToppCellwk_08-11-Epithelial-PNS-TM4SF4+_CHODL+_neuron|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

GPR22 SCG2 SYT1 ZNF804A ALK

8.97e-06198635eb3c389e7452d74e5e15179503e480d6d11ca9ca
ToppCellMS-Multiple_Sclerosis-Others-HSPC|Multiple_Sclerosis / Disease, condition lineage and cell class

IGF2BP2 HPGDS KBTBD12 ZNF804A NEDD4

9.19e-061996357f4a22207a8b27af9a070d289e31ebd0e57af1a6
ToppCellTCGA-Peripheral_Nervous_System|World / Sample_Type by Project: Shred V9

AMPD2 GPR22 SCG2 SYT1

5.18e-051446343bbadb4b07ffb461d5400a5d69ad3b259f74041e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

STON1 PIK3C2G KCNJ16 CFB

6.39e-05152634eee86b508b8f140ea44e21d8c04c409a7b689e39
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3CB KCNJ16 GEN1 CHRNB1

6.39e-05152634b61d2f6ee819c8dd4b4b601a8bc8388b1983de58
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IQCH IQCC DLEC1 DNAH1

6.72e-051546349ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IQCH IQCC DLEC1 DNAH1

6.72e-0515463458072ce422d09f2de602580325eaac6c4ec6c136
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4/8-lo-Trm_Tgd|lymph-node_spleen / Manually curated celltypes from each tissue

ERCC2 PDE4A IQCC GEN1

6.89e-05155634b0e456c4915076e1d38282e116a6eb3230ae80dc
ToppCelldroplet-Liver-Hepatocytes-18m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGF2BP2 IQCC PIK3CB KCNJ16

7.42e-05158634d3446fc98eff09c3626b47a2c90d07cd985378b5
ToppCelldroplet-Liver-Hepatocytes-18m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGF2BP2 IQCC PIK3CB KCNJ16

7.42e-05158634df614450e10629dc9115d7365397663e82f9e48f
ToppCelldroplet-Lung-nan-18m-Lymphocytic-plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRYBG2 TP53INP1 SYT1 GEN1

8.37e-051636345efecdd8a069a822bc9d35b407092925a865e629
ToppCellnormal_Pleural_Fluid-Myeloid_cells-Undetermined|Myeloid_cells / Location, Cell class and cell subclass

MXRA5 HPGDS RHOV RPL15

8.37e-05163634be774c0ba38fa89a9c0076524cf05d593c6c6826
ToppCelldroplet-Lung-nan-18m-Lymphocytic-Plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRYBG2 TP53INP1 SYT1 GEN1

8.37e-051636340d94a427f86e62aba12c397c6d7b8cd297f3a0e5
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-plasma_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CRYBG2 TP53INP1 SYT1 GEN1

8.57e-05164634b92e7c91910d518627376166c6ea9ed333b3d07e
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-plasma_cell-plasma_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CRYBG2 TP53INP1 SYT1 GEN1

8.57e-05164634a1e43c6b3e2553f5604100db6e92bf244b70c36d
ToppCellfacs-Skin-Anagen-24m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRYBG2 PIK3C2G RHOV CHRM5

9.20e-0516763402c89069dcd0e87f7502e32b14e7cbd3cab81a09
ToppCellPosterior_cortex-Neuronal-Inhibitory|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SCG2 ZNF804A ALK IGSF3

9.20e-051676349a84f45345c75f2c8ff38a04245aadee2a26a240
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-5_VIP_KCNJ2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MXRA5 SCG2 ZNF804A IGSF3

1.08e-04174634fdadac1eaab2c4a67e4832f0901df22e893add6a
ToppCellPND07-Epithelial-Epithelial_Airway-Neurosecretory|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPR22 RHOV SCG2 ZNF804A

1.10e-0417563419eda8b5d39dc93d79737ebdbeeba5ec0cb23c51
ToppCellPCW_13-14-Neuronal-Neuronal_postreplicative-neuro_NA|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GPR22 SCG2 ZNF804A ALK

1.15e-041776348c78f7de091f16e86e326a73c9f1429e0232821f
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SCG2 ZNF804A ALK NEDD4

1.20e-041796343b0f8781232e1d42b6f8913bc989a14b3f978e79
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SCG2 ZNF804A ALK NEDD4

1.25e-04181634153709b4dd3d81e09f251fa8765b58bed1932fda
ToppCell343B-Lymphocytic-NK_cells-NK_cell_A2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

CD5 PIK3CB CCDC34 DNAH1

1.28e-0418263403992d0ae519795239e4f2cc8e63f33c4482de6a
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HPGDS RHOV MAP3K10 CRAMP1

1.28e-0418263457f8b8d7b132f3ad6f2b1e79c3812fe938657d2c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MXRA5 PIK3C2G RHOV RPL15

1.34e-041846349690d4290e70f9bda889754ffb30b0af1f7cb94b
ToppCellPCW_13-14-Neuronal|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GPR22 SCG2 ZNF804A ALK

1.34e-0418463465cf3460125e3dbc34978957bc138a449f71f7df
ToppCellPND07-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPR22 SCG2 SYT1 ZNF804A

1.34e-041846343e5c68a99c10eb1ddc1048bea4aa9f6b8e2746ff
ToppCellPND07-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPR22 SCG2 SYT1 ZNF804A

1.34e-041846341e2f0cec50475a1cf2973a5082826bbc60fc9a68
ToppCellCOVID-19_Moderate-HSPC|World / disease group, cell group and cell class

CLIP3 IGF2BP2 HPGDS NEDD4

1.34e-04184634ccc93babe1fcdeb66b78e1d8414357877a7c45bd
ToppCelldroplet-Marrow-nan-18m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TP53INP1 SYT1 ZNF804A CHRNB1

1.36e-04185634238938a4682b44e88a30b86b13af4feeabe9553d
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1C CLIP3 SYT1 PZP

1.39e-041866346add08d4ca019ff2864acdd5ec2c66a59a574591
ToppCellwk_15-18-Epithelial-PNS-MFNG+_DBH+_neuron|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

GPR22 SCG2 SYT1 ALK

1.39e-0418663472f7427d62d65e37bb0bf99229a1b75df081a128
ToppCellPCW_07-8.5-Neuronal-Neuronal_postreplicative|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

GPR22 SCG2 ZNF804A ALK

1.39e-041866342fdd0a80ad31cf017aafcf5dcf760ebd786b98c1
ToppCellPCW_13-14-Neuronal-Neuronal_postreplicative|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GPR22 SCG2 ZNF804A ALK

1.39e-04186634cf96f880e6e22189593ce1357c55e65c34644559
ToppCellPCW_07-8.5-Neuronal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

GPR22 SCG2 ZNF804A ALK

1.39e-041866347a4bb42f3f6a27b463e48eafc587d9ab3386f2fb
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MXRA5 PIK3C2G RHOV MAP3K21

1.39e-04186634b3358e0fa6d845c81e94d56c8575f016621d28ff
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|lymph-node_spleen / Manually curated celltypes from each tissue

IGF2BP3 ERCC2 VILL SEC16A

1.42e-041876343c10b8501226c69d71bcd99dc1c064a3c2154f87
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

RHOV SCG2 SYT1 CHRM5

1.45e-04188634b73e8a40393c3f656e2fcfe395a761b1f985c254
ToppCellPCW_07-8.5-Neuronal-Neuronal_postreplicative-neuro_immature_neuronal_(2)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

GPR22 SCG2 ZNF804A ALK

1.48e-04189634de06ef69f3f97b3f21dc269eb6965da9b2f6e3f8
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1C CLIP3 SYT1 PZP

1.54e-041916347853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

RHOV SCG2 SYT1 ZNF804A

1.54e-041916345d24022cec293bc8d9e978ae99a109e660bb8f83
ToppCellEntopeduncular-Neuronal-Inhibitory|Entopeduncular / BrainAtlas - Mouse McCarroll V32

RHOV SCG2 SYT1 ZNF804A

1.54e-0419163473dae4cdea86aec62393ad7303dc7375a6b3fc86
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1C CLIP3 SYT1 ZNF804A

1.54e-04191634b133ee1c0e58d00ddd2e4e05b01fd04947524c18
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR22 SCG2 SYT1 ALK

1.57e-04192634d8f5df2c2a50e567f24ebecc8033ac97ba89d9c5
ToppCell11.5-Airway-Epithelial-Epithelial|Airway / Age, Tissue, Lineage and Cell class

GPR22 SCG2 ZNF804A ALK

1.57e-04192634a77d3692ff02ef7e066a9bd9e22725055a25c4d4
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR22 SCG2 SYT1 ZNF804A

1.57e-041926342f1c4ef693515ccc7231bd8c6641fad51d445d20
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GPR22 CCDC34 PCDH11X SYT1

1.57e-04192634f518839ecd9377537a414e8798766f7d91eafeac
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_B|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR22 SCG2 SYT1 ALK

1.60e-041936349661ea0ee7273928c7de2a9f49e853595fa77699
ToppCellLAM-LAM-LAM+|LAM / Condition, Lineage and Cell class

CACNA1C CLIP3 GPR22 SYT1

1.64e-041946344ba73a9145ed44896e359f6df9c1f32bbe24a189
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR22 SCG2 SYT1 ALK

1.64e-041946345bd0f739aa75f387cca7c3b2686493ee2d1ee968
ToppCellLAM-LAM|LAM / Condition, Lineage and Cell class

CACNA1C CLIP3 GPR22 SYT1

1.64e-041946344c6561a64711c72c4ef4a3e67c41d2e8d31fba57
ToppCellfacs-Brain_Myeloid-Hippocampus|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JAK1 HPGDS SCG2 APC

1.67e-04195634a1478021a3ed0e779716393124ca2a7770c433b7
ToppCell15-Trachea-Epithelial-Epithelial|Trachea / Age, Tissue, Lineage and Cell class

CLIP3 GPR22 SYT1 ZNF804A

1.67e-041956349e9283a397f56732a0a5f2e2527f154d4c2dd56a
ToppCellwk_08-11-Epithelial-PNS-TM4SF4+_PENK+_neuron|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

GPR22 SCG2 SYT1 ALK

1.70e-04196634afa3a2f5f3a51d1830c6f95f97a4b3e13ed42512
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR22 SYT1 ZNF804A ALK

1.77e-041986346483d412b6c0aab58b3348f99231caa5daf65025
ToppCellParenchymal-NucSeq-Stromal-Pericyte-Muscle_pericyte_systemic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C PIK3C2G AOC3 CRAMP1

1.77e-04198634882710bd6215e299257dd3df234292db9a2823ba
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MXRA5 PIK3C2G KCNJ16 CFB

1.77e-041986340d9d401190792fd61434f1b82548253187d805f0
ToppCellFetal_29-31_weeks|World / Lineage, Cell type, age group and donor

CACNA1C IGF2BP3 IGF2BP2 RPL15

1.80e-041996345b9d355795dd03a22f0961dfd143425c367a4654
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M|organoid_Kanton_Nature / Sample Type, Dataset, Time_group, and Cell type.

GPR22 SCG2 APC SYT1

1.80e-04199634b2d7dea11207cca63d688f8051143850b29dbdf0
ToppCellCOVID-19-COVID-19_Severe-Others-HSPC|COVID-19_Severe / Disease, condition lineage and cell class

CLIP3 IGF2BP2 HPGDS NEDD4

1.80e-0419963425de67b6c9c8d6bb9a538e071a40ef865906c95d
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

IQCH VILL DLEC1 DNAH1

1.80e-0419963460919c2af31d39a2d36d7bc432e43dab2a4e05fb
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6|World / Primary Cells by Cluster

GPR22 PCDH11X APC RPL15

1.80e-041996341b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCellCOVID-19-COVID-19_Mild-Others-HSPC|COVID-19_Mild / Disease, condition lineage and cell class

CLIP3 IGF2BP2 HPGDS NEDD4

1.80e-041996340230103c37ae3aff58240739b89f2c36b1e39a69
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal|World / Primary Cells by Cluster

GPR22 PCDH11X APC RPL15

1.80e-041996344bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCellLPS_anti-TNF-Epithelial_airway|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

IQCH VILL DLEC1 DNAH1

1.80e-041996346aca164bbbb961f34b1e6f1857f91ade5c059405
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MXRA5 PIK3C2G KCNJ16 MAP3K21

1.80e-041996343cd6383c50ce342fe5c175e2e50784d634a90e80
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

IQCH PIK3C2G DLEC1 DNAH1

1.84e-0420063496701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

IQCH VILL DLEC1 DNAH1

1.84e-04200634da12821e8a0657869ca0f75d351cce2d7605a505
ToppCellParenchymal-10x5prime-Stromal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C CLIP3 MXRA5 AOC3

1.84e-042006342e525c0d9684e7a2275edb04e1addb6fc6a872e5
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-ADAMTSL1|Neuronal / cells hierarchy compared to all cells using T-Statistic

MXRA5 SCG2 ZNF804A IGSF3

1.84e-04200634e1fca7ee2dc18c7fded53c3561f519c1fcd9767a
ToppCellBronchus_Control_(B.)-Stromal-TX-Fibroblasts-1|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

CACNA1C CLIP3 MXRA5 STON1

1.84e-0420063416a3685c41194a0a4a772e4eee372160263480e0
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

JAK1 IGF2BP3 IGF2BP2 NEDD4

1.84e-042006343585484c7e24e941708bee471ca607d8ccee74e6
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Interneuron|5w / Sample Type, Dataset, Time_group, and Cell type.

GPR22 APC SYT1 IGSF3

1.84e-04200634c7e33057466915d4e2b34f2062b22d9cdffa69dc
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-ADAMTSL1-L1-3|Neuronal / cells hierarchy compared to all cells using T-Statistic

MXRA5 SCG2 ZNF804A IGSF3

1.84e-042006344409471479dd7c0f770bcb84ba7b3652c4706743
ToppCellLPS_IL1RA_TNF-Epithelial_airway|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

IQCH VILL DLEC1 DNAH1

1.84e-0420063472c1d9eeaed4b3ee6b6c602e8aa29efc2e8744eb
DrugNsc82118

AOC2 AOC3 CFB

2.01e-075633CID000164749
Drugethylglyoxal

AOC2 AOC3 CFB

4.01e-076633CID000145744
DrugAC1L3Y6U

AOC2 AOC3 CFB

7.01e-077633CID000097282
DrugDrotaverine

CACNA1C PDE4A

7.54e-062632DB06751
Drugdiphenylglyoxal bis(guanylhydrazone

AOC2 AOC3

7.54e-062632CID000357080
DrugAC1Q77R6

AOC2 AOC3

7.54e-062632CID000094259
DrugDPGBG

AOC2 AOC3

7.54e-062632CID005356884
Drugmonopropionylcadaverine

AOC2 AOC3

7.54e-062632CID000194207
Drugp-dimethylaminomethylbenzaldehyde

AOC2 AOC3

7.54e-062632CID000193251
Drug1-carboxymethylpyridinium

AOC2 AOC3

7.54e-062632CID000080439
Drugisoputreanine

AOC2 AOC3

7.54e-062632CID000171763
Drugsupinidine

AOC2 AOC3

7.54e-062632CID000164663
DrugN-(3-aminopropyl)pyrrolidin-2-one

AOC2 AOC3

7.54e-062632CID000082111
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A

CRYBG2 MXRA5 STON1 IQCC SCG2 BBS9

1.35e-051886363177_UP
Drug2-bromoethylamine

AOC2 AOC3 ALK

1.60e-0518633CID000007851
DrugCholecalciferol [67-97-0]; Up 200; 10.4uM; MCF7; HT_HG-U133A

IQCC HPGDS ETNK2 APC GGA1 CHRNB1

1.65e-051956363298_UP
DrugAC1L1B7L

AOC2 AOC3

2.26e-053632CID000026477
Drug3-aminopropionamide

AOC2 AOC3

2.26e-053632CID000192802
Drugpentafluorobenzamide

AOC2 AOC3

2.26e-053632CID000069547
Drugacisoga

AOC2 AOC3

2.26e-053632CID000129397
Drug(+)-Cyanustine

AOC2 AOC3

2.26e-053632CID000028846
Drugpropylglyoxal

AOC2 AOC3

2.26e-053632CID000123249
Drug3-Hydroxycadaverine

AOC2 AOC3

2.26e-053632CID000435285
Drug5-fluoropentane-1,4-diamine

AOC2 AOC3

2.26e-053632CID010011890
DrugNSD-1531

AOC2 AOC3

2.26e-053632CID003014318
DrugNazlinine

AOC2 AOC3

2.26e-053632CID000126237
Drug5-aminopentanal

AOC2 AOC3

2.26e-053632CID000443849
Drugnecic acid

AOC2 AOC3

2.26e-053632CID006440847
DrugAC1L34PU

AOC2 AOC3

2.26e-053632CID000134498
Drugh202

AOC2 AOC3

2.26e-053632CID000013826
Drugamicarbalide

AOC2 AOC3

2.26e-053632CID000072074
DrugN-(4-aminobutyl)aziridine

AOC2 AOC3

2.26e-053632CID000152643
DrugC10974

AOC2 AOC3

2.26e-053632CID000443042
Drugalpha-difluoromethyl putrescine

AOC2 AOC3

2.26e-053632CID000135151
Drugketosuccinamate

AOC2 AOC3

2.26e-053632CID000439716
DrugN-(3-aminopropyl)aziridine

AOC2 AOC3

2.26e-053632CID000014076
Drugethylmethylglyoxal bis(guanylhydrazone

AOC2 AOC3

2.26e-053632CID000129202
Drugmethylglyoxal bis(guanylhydrazone

ERCC2 AOC2 AOC3 CFB

2.47e-0561634CID000009991
Drug3-methyladenine

ERCC2 TP53INP1 PIK3C2G PIK3CB ALK

3.50e-05134635CID000001673
Drugbaryta

ERCC2 AOC2 KCNJ16 AOC3 CFB

3.76e-05136635CID000062392
Drugplastoquinol-9

AOC2 FES CFB

3.92e-0524633CID006440941
DrugICR-191

JAK1 ERCC2 PEX6

3.92e-0524633CID000028240
Drugmalonamate

AOC2 AOC3

4.51e-054632CID000075367
Drug2-aminoresorcinol

AOC2 AOC3

4.51e-054632CID000069450
DrugEovist (TN)

AOC2 AOC3

4.51e-054632CID009961939
DrugAC1Q3E6A

AOC2 AOC3

4.51e-054632CID000068318
Drugspermic acid

AOC2 AOC3

4.51e-054632CID000167029
DrugN-acetyl-1,6-diaminohexane

AOC2 AOC3

4.51e-054632CID000162081
Drug3-aminooxy-2-fluoro-1-propanamine

AOC2 AOC3

4.51e-054632CID000126496
Drug2-Butene-1,4-diamine

AOC2 AOC3

4.51e-054632CID000148401
Druglanthionamine

AOC2 AOC3

4.51e-054632CID000070096
DrugN-methylpyrrolinium

AOC2 AOC3

4.51e-054632CID000440932
Drugdimethylpyridine

AOC2 AOC3

4.51e-054632CID000011420
Drug1,4-diamino-2-butyne

AOC2 AOC3

4.51e-054632CID000124159
Drugpiperideine

AOC2 AOC3

7.50e-055632CID000068161
Druggeranylamine

AOC2 AOC3

7.50e-055632CID000160248
Drugallyl formate

STON1 AOC3

7.50e-055632CID000061278
Drugphenamidine

AOC2 AOC3

7.50e-055632CID000064948
DrugNSD 1039

AOC2 AOC3

7.50e-055632CID000193408
DrugNSD 1024

AOC2 AOC3

7.50e-055632CID000188951
DrugN(8)-(2-carboxyethyl)spermidine

AOC2 AOC3

7.50e-055632CID000125245
Drugoxosparteine

AOC2 AOC3

7.50e-055632CID000097492
Drugalpha-hydrazinohistidine

AOC2 AOC3

7.50e-055632CID000169499
Drugperhydroazepinyl

AOC2 AOC3

7.50e-055632CID000123152
Drug2-fluoroputrescine

AOC2 AOC3

7.50e-055632CID000147066
Drugpelletierine

AOC2 AOC3

7.50e-055632CID000092987
Drug1,4-diamino-2-butanone

AOC2 AOC3

7.50e-055632CID000151733
Drug16 d

ERCC2 AOC2 AOC3

7.77e-0530633CID000016401
DrugAC1MBZ1C

CACNA1C PDE4A P2RY11 PIK3C2G PIK3CB SCG2 SYT1

9.47e-05387637CID000003541
Drugquinuclidinyl benzilate

AOC3 PZP CHRM5 CHRNB1

9.97e-0587634CID000023056
DrugNSC614854

AOC2 AOC3

1.12e-046632CID000122633
Drugisothiouronium

AOC2 AOC3

1.12e-046632CID000031429
Drugtrihydroxyphenylalanine

AOC2 AOC3

1.12e-046632CID000591034
Drugcyclohexanone oxime

AOC2 AOC3

1.12e-046632CID000007517
DrugFF-705

AOC2 AOC3

1.12e-046632CID000126643
Drug1,4-dimethylputrescine

AOC2 AOC3

1.12e-046632CID000162247
Drugputreanine

AOC2 AOC3

1.57e-047632CID000161506
DrugGYKI 11.121

AOC2 AOC3

1.57e-047632CID000193769
Drugp-dimethylaminomethylbenzylamine

AOC2 AOC3

1.57e-047632CID000193714
Drug2-hydrazinopyridine

AOC2 AOC3

1.57e-047632CID000078645
DrugAC1L28PE

AOC2 AOC3

1.57e-047632CID000067954
Drugtele-methylhistamine

TP53INP1 AOC2 AOC3

1.59e-0438633CID000003614
DrugMethimazole [60-56-0]; Up 200; 35uM; MCF7; HT_HG-U133A

RPAP1 SCG2 ZMYND8 APC BBS9

1.91e-041926353432_UP
DrugTrimethadione [127-48-0]; Up 200; 28uM; MCF7; HT_HG-U133A

ERCC2 ZMYND8 GGA1 ALK CHRNB1

1.91e-041926352846_UP
DrugLasalocid sodium salt [25999-20-6]; Down 200; 6.6uM; PC3; HT_HG-U133A

ZMYND8 APC PCNX1 GGA1 BBS9

1.91e-041926356639_DN
Drugorthovanadate

JAK1 PDE4A PIK3C2G PIK3CB AOC2 AOC3 DNAH1

1.95e-04435637CID000061672
DrugChlorpheniramine maleate [113-92-8]; Up 200; 10.2uM; PC3; HT_HG-U133A

NEK3 CRYBG2 ETNK2 ZMYND8 CHRNB1

1.96e-041936352055_UP
DrugPF-01378883-00 [351320-41-7]; Up 200; 10uM; PC3; HT_HG-U133A

CRYBG2 ETNK2 APC SYT1 ALK

2.01e-041946356368_UP
DrugCarbetapentane citrate [23142-01-0]; Up 200; 7.6uM; MCF7; HT_HG-U133A

CRYBG2 ERCC2 PDE4A MXRA5 CD5

2.01e-041946355610_UP
DrugDosulepin hydrochloride [897-15-4]; Down 200; 12uM; MCF7; HT_HG-U133A

RPAP1 ZMYND8 APC GGA1 BBS9

2.01e-041946352864_DN
Drugvanadyl

JAK1 PDE4A PIK3C2G PIK3CB FES DNAH1

2.04e-04307636CID000061671
DrugChlorogenic acid [327-97-9]; Up 200; 11.2uM; MCF7; HT_HG-U133A

IQCC ZMYND8 GGA1 BBS9 CHRNB1

2.06e-041956353282_UP
DrugClomiphene citrate (Z,E) [50-41-9]; Down 200; 6.6uM; PC3; HT_HG-U133A

STON1 PIK3CB APC SYT1 PCNX1

2.06e-041956356648_DN
DrugPramoxine hydrochloride [637-58-1]; Down 200; 12.2uM; MCF7; HT_HG-U133A

ERCC2 STON1 RPAP1 IQCC APC

2.06e-041956354368_DN
DrugMedina G

APC CRAMP1

2.09e-048632CID000171284
Drughyamine hydroxide

AOC2 AOC3

2.09e-048632CID000014842
Drug1,2-diaminoguanidine

AOC2 AOC3

2.09e-048632CID000170039
DrugNSC-356893

AOC2 AOC3

2.09e-048632CID000434770
DrugZ H-H

AOC2 AOC3

2.09e-048632CID000004657
DrugQ 192

AOC2 AOC3

2.09e-048632CID000077317
Diseaseacquired metabolic disease (implicated_via_orthology)

IGF2BP3 IGF2BP2

2.52e-054612DOID:0060158 (implicated_via_orthology)
DiseaseSchizophrenia

CACNA1C IGF2BP2 PDE4A HPGDS PIK3CB APC ZNF804A CHRM5 ALK

7.94e-05883619C0036341
Diseaseprostate cancer (is_implicated_in)

JAK1 ERCC2 PIK3CB APC

1.03e-04117614DOID:10283 (is_implicated_in)
Diseasebrain connectivity measurement

JAK1 STON1 KCNJ16 FES SYT1 NEDD4

1.77e-04400616EFO_0005210
DiseaseDental enamel hypoplasia

SYT1 MAP3K21

2.74e-0412612EFO_1001304
Diseasestomach cancer (is_implicated_in)

JAK1 ERCC2 APC

4.53e-0472613DOID:10534 (is_implicated_in)
Diseasecongenital myasthenic syndrome (implicated_via_orthology)

SYT1 CHRNB1

4.95e-0416612DOID:3635 (implicated_via_orthology)
Diseasehepatocellular carcinoma (is_implicated_in)

JAK1 ERCC2 FES APC

5.44e-04181614DOID:684 (is_implicated_in)
DiseaseGlioma

PPM1D APC ALK

7.87e-0487613C0017638
Diseaseunipolar depression, schizophrenia

CACNA1C ZNF804A

1.22e-0325612EFO_0003761, MONDO_0005090
Diseasemacular degeneration (is_implicated_in)

ERCC2 CFB

1.43e-0327612DOID:4448 (is_implicated_in)
DiseaseBreast Cancer, Familial

PPM1D GEN1

1.76e-0330612C0346153
Diseasewhite matter volume measurement

SYT1 ZNF804A

2.00e-0332612EFO_0008320

Protein segments in the cluster

PeptideGeneStartEntry
EPREHQPLPIQWKIQ

CD5

226

P06127
GQWEIIHKPSRLIQP

CHRNB1

206

P11230
HRVHSPNVRWLVQVP

AMPD2

561

Q01433
VPWSPEHQLQRLQVT

AOC3

551

Q16853
QAPHWSVRVRKAENP

RAB3GAP1

306

Q15042
VKEDNLVHWERPQRP

PZP

1181

P20742
QHAQPVNEKRFPTWR

IQCH

716

Q86VS3
LGIQWRHKPNVVSVE

JAK1

321

P23458
PSHEGQKKQRTIPWR

IQCC

421

Q4KMZ1
PETWVHRINFPLEIK

PIK3C2G

536

O75747
PEHWLQRPQLTRQVL

AOC2

551

O75106
HKQPWQAKISVIRPS

CFB

491

P00751
RKQRPWHPAVVFSVQ

P2RY11

56

Q96G91
VPPHVLVNWAVQVAR

MAP3K10

191

Q02779
INHNIKRTQWEDPRL

NEDD4

911

P46934
VQAIPAVANWIKRRP

HPGDS

181

O60760
IQELRPHWKPEQVRT

ETNK2

71

Q9NVF9
VTHYVLPQVRKQLPW

PCNX1

1306

Q96RV3
QHLWRQPRTPIRIQQ

PDE4A

31

P27815
QPHLARVQVLEPRWD

PEX6

236

Q13608
IRHRWGLPQKIQQSI

FAM205A

601

Q6ZU69
IQKQSIRHRWGLPQK

FAM205BP

326

Q63HN1
IRHRWGLPQKIQQSI

FAM205BP

331

Q63HN1
KWRLRVQHVVQESPP

ERCC2

341

P18074
QVRWEKQQPTPRLTL

GGA1

441

Q9UJY5
SRKIQIRNIPPHLQW

IGF2BP2

81

Q9Y6M1
VNRVVWKRPRLTHNG

PPM1D

241

O15297
IWIHPQPQRKSEGKV

PCDH11X

1031

Q9BZA7
RKLQIRNIPPHLQWE

IGF2BP3

81

O00425
KWATQLPHIPVAVRV

BBS9

321

Q3SYG4
PNLHRRQWEKNVPNT

NEK3

356

P51956
VEIPTHQPQRHWIKR

DNAH1

4241

Q9P2D7
RAIANVPPIQEKRHW

CRNKL1

516

Q9BZJ0
VWKPNHPERETVARL

IGSF3

856

O75054
VDHPIIQPRSWENSK

CACNA1C

1101

Q13936
EQKQVRLPESRLTPW

CCDC34

131

Q96HJ3
TWRQRPPTQEEIKHG

CRYBG2

21

Q8N1P7
VPIELQPRNNHAWAR

CRAMP1

321

Q96RY5
QQKPLPVSRWAQIHL

MAN2B1

666

O00754
LWQILEPVKQHIPLR

GEN1

6

Q17RS7
RQWVPQVQHKIDVIG

CLIP3

86

Q96DZ5
PNNAVIHNSWIDPKR

GPR22

396

Q99680
PRNKNWMNHLRVPQR

DLEC1

296

Q9Y238
LPKETAPAVQRVVWN

ZMYND8

806

Q9ULU4
VERDNWKRVSPLPLQ

KBTBD12

411

Q3ZCT8
NREPLVKIWHEIRTN

PARL

356

Q9H300
QLIPEVQKPLHEQLW

FES

446

P07332
ANPRRPIAQWHTLQV

SYT1

396

P21579
RIPPHVLVNWAVQIA

MAP3K21

231

Q5TCX8
NQLPKAAWIPHVENR

SCG2

476

P13521
PPKKTRIISHVWENN

PIK3CB

316

P42338
PVNHQPLERHRLWEV

CHRM5

16

P08912
PHTPQWQVRTLKDAR

ALK

496

Q9UM73
QSPSQNERWARPKHI

APC

1041

P25054
ANQVLEWVRAPPHVR

CHST14

306

Q8NCH0
ITEKWLPEIRTHNPQ

RHOV

121

Q96L33
KHPEQIFPRQRAIQW

MRPS9

126

P82933
PRIVNHWASPELRQN

SEC16A

306

O15027
DNIRIHFPVPSQWIK

STON1

566

Q9Y6Q2
AIRRNPDTQWITKPV

RPL15

141

P61313
PSQWIKEHSERQPLN

TP53INP1

191

Q96A56
WKDQQLHIEKAPPVR

KCNJ16

346

Q9NPI9
KLHWTQDLPPVRRQQ

RPAP1

336

Q9BWH6
WCIQDLHRQPVDPKR

VILL

396

O15195
VPVLNKHRSTVLQWP

ZNF804A

426

Q7Z570
EDRKTVWIHVNVQPP

MXRA5

2426

Q9NR99