Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
MousePheno	sclera thinning	FMOD LUM	1.69e-05	2	58	2	MP:0003102
Domain	GPR_3/6/12_orphan	GPR3 GPR12	4.26e-05	3	71	2	IPR000723
Domain	-	GTF2IRD2B GTF2IRD2	8.51e-05	4	71	2	3.90.1460.10
Domain	GTF2I	GTF2IRD2B GTF2IRD2	8.51e-05	4	71	2	PS51139
Domain	GTF2I	GTF2IRD2B GTF2IRD2	8.51e-05	4	71	2	PF02946
Domain	GTF2I	GTF2IRD2B GTF2IRD2	8.51e-05	4	71	2	IPR004212
Domain	LRRNT	FMOD NTRK3 LUM	1.08e-03	53	71	3	PF01462
Domain	DEP	GPR155 RGS7	3.13e-03	22	71	2	PF00610
Domain	DEP	GPR155 RGS7	3.13e-03	22	71	2	PS50186
Domain	DEP	GPR155 RGS7	3.13e-03	22	71	2	SM00049
Domain	DEP_dom	GPR155 RGS7	3.42e-03	23	71	2	IPR000591
Domain	LRRNT	FMOD NTRK3 LUM	6.19e-03	98	71	3	IPR000372
Domain	LRRNT	FMOD NTRK3 LUM	6.19e-03	98	71	3	SM00013
Pubmed	The atypical homeodomain transcription factor Mohawk controls tendon morphogenesis.	COL5A1 FMOD LUM	1.39e-06	11	72	3	20696843
Pubmed	Development of myotendinous-like junctions that anchor cardiac valves requires fibromodulin and lumican.	FMOD LUM	4.23e-06	2	72	2	27503167
Pubmed	Ubiquitin-specific protease activity of USP9Y, a male infertility gene on the Y chromosome.	USP9X USP9Y	4.23e-06	2	72	2	12895410
Pubmed	Identification of Lumican and Fibromodulin as Hub Genes Associated with Accumulation of Extracellular Matrix in Diabetic Nephropathy.	FMOD LUM	4.23e-06	2	72	2	33887734
Pubmed	A syndrome of joint laxity and impaired tendon integrity in lumican- and fibromodulin-deficient mice.	FMOD LUM	4.23e-06	2	72	2	12089156
Pubmed	Macrophage-secreted MMP9 induces mesenchymal transition in pancreatic cancer cells via PAR1 activation.	MMP9 F2R	4.23e-06	2	72	2	32809114
Pubmed	The Drosophila developmental gene fat facets has a human homologue in Xp11.4 which escapes X-inactivation and has related sequences on Yq11.2.	USP9X USP9Y	4.23e-06	2	72	2	8922996
Pubmed	Homologous sequence in lumican and fibromodulin leucine-rich repeat 5-7 competes for collagen binding.	FMOD LUM	4.23e-06	2	72	2	19008226
Pubmed	Ocular and scleral alterations in gene-targeted lumican-fibromodulin double-null mice.	FMOD LUM	4.23e-06	2	72	2	12766039
Pubmed	Usp9y (ubiquitin-specific protease 9 gene on the Y) is associated with a functional promoter and encodes an intact open reading frame homologous to Usp9x that is under selective constraint.	USP9X USP9Y	4.23e-06	2	72	2	12925892
Pubmed	Fibromodulin regulates collagen fibrillogenesis during peripheral corneal development.	FMOD LUM	4.23e-06	2	72	2	20108350
Pubmed	The G-protein-coupled receptors GPR3 and GPR12 are involved in cAMP signaling and maintenance of meiotic arrest in rodent oocytes.	GPR3 GPR12	4.23e-06	2	72	2	16229830
Pubmed	Targeting CLA/E-selectin interactions prevents CCR4-mediated recruitment of human Th2 memory cells to human skin in vivo.	SELE CCR4	4.23e-06	2	72	2	12555662
Pubmed	Comparison of TFII-I gene family members deleted in Williams-Beuren syndrome.	GTF2IRD2B GTF2IRD2	4.23e-06	2	72	2	15388857
Pubmed	Increased vascular MMP-9 in mice lacking RNF213: moyamoya disease susceptibility gene.	RNF213 MMP9	4.23e-06	2	72	2	25383461
Pubmed	Differential expression of lumican and fibromodulin regulate collagen fibrillogenesis in developing mouse tendons.	FMOD LUM	4.23e-06	2	72	2	11076963
Pubmed	Involvement of PU.1 in mast cell/basophil-specific function of the human IL1RL1/ST2 promoter.	SPI1 IL1RL1	4.23e-06	2	72	2	22824976
Pubmed	Sex differences in sex chromosome gene expression in mouse brain.	USP9X USP9Y KDM6A	6.79e-06	18	72	3	12023983
Pubmed	A domain-specific usherin/collagen IV interaction may be required for stable integration into the basement membrane superstructure.	COL5A1 USH2A	1.27e-05	3	72	2	14676276
Pubmed	cDCBLD2 mediates sorafenib resistance in hepatocellular carcinoma by sponging miR-345-5p binding to the TOP2A coding sequence.	DCBLD2 TOP2A	1.27e-05	3	72	2	37781045
Pubmed	Neural expression of G protein-coupled receptors GPR3, GPR6, and GPR12 up-regulates cyclic AMP levels and promotes neurite outgrowth.	GPR3 GPR12	1.27e-05	3	72	2	17284443
Pubmed	Anti-HMGCR Antibody-Positive Myopathy Shows Bcl-2-Positive Inflammation and Lymphocytic Accumulations.	CCR4 HMGCR	1.27e-05	3	72	2	32100014
Pubmed	Expression of lumican and fibromodulin following interleukin-1 beta stimulation of disc cells of the human temporomandibular joint.	FMOD LUM	1.27e-05	3	72	2	22073367
Pubmed	PU.1 binds to a distal regulatory element that is necessary for B cell-specific expression of CIITA.	SPI1 DNASE1	1.27e-05	3	72	2	20363966
Pubmed	Deubiquitinase USP9X regulates the invasion of prostate cancer cells by regulating the ERK pathway and mitochondrial dynamics.	USP9X MMP9	1.27e-05	3	72	2	31002345
Pubmed	Factors which Influence the Levels of ST-2, Galectin-3 and MMP-9 in Acute Coronary Syndrome.	IL1RL1 MMP9	1.27e-05	3	72	2	31438834
Pubmed	Molecular cloning and chromosomal localization of human genes encoding three closely related G protein-coupled receptors.	GPR3 GPR12	1.27e-05	3	72	2	8530049
Pubmed	Knockdown the moyamoya disease susceptibility gene, RNF213, upregulates the expression of basic fibroblast growth factor and matrix metalloproteinase-9 in bone marrow derived mesenchymal stem cells.	RNF213 MMP9	1.27e-05	3	72	2	38811382
Pubmed	Fluid shear stress differentially regulates gpr3, gpr6, and gpr12 expression in human umbilical vein endothelial cells.	GPR3 GPR12	1.27e-05	3	72	2	12649592
Pubmed	Isolation and characterisation of GTF2IRD2, a novel fusion gene and member of the TFII-I family of transcription factors, deleted in Williams-Beuren syndrome.	GTF2IRD2B GTF2IRD2	1.27e-05	3	72	2	15100712
Pubmed	Molecular cloning of a novel putative G protein-coupled receptor (GPCR21) which is expressed predominantly in mouse central nervous system.	GPR3 GPR12	1.27e-05	3	72	2	8262253
Pubmed	Lumican effects in the control of tumour progression and their links with metalloproteinases and integrins.	LUM MMP9	1.27e-05	3	72	2	23438179
Pubmed	Associations of 25 structural, degradative, and inflammatory candidate genes with lumbar disc desiccation, bulging, and height narrowing.	COL5A1 IL1RL1 MMP9	1.89e-05	25	72	3	19180518
Pubmed	Evolution of general transcription factors.	GTF2IRD2B GTF2IRD2	2.53e-05	4	72	2	23229069
Pubmed	GTF2IRD2 from the Williams-Beuren critical region encodes a mobile-element-derived fusion protein that antagonizes the action of its related family members.	GTF2IRD2B GTF2IRD2	2.53e-05	4	72	2	22899722
Pubmed	IL‑33 enhances glioma cell migration and invasion by upregulation of MMP2 and MMP9 via the ST2-NF-κB pathway.	IL1RL1 MMP9	2.53e-05	4	72	2	28849217
Pubmed	The endoplasmic reticulum-resident collagen chaperone Hsp47 interacts with and promotes the secretion of decorin, fibromodulin, and lumican.	FMOD LUM	2.53e-05	4	72	2	30002123
Pubmed	TFII-I gene family during tooth development: candidate genes for tooth anomalies in Williams syndrome.	GTF2IRD2B GTF2IRD2	2.53e-05	4	72	2	17823943
Pubmed	Haploinsufficiency of Gtf2i, a gene deleted in Williams Syndrome, leads to increases in social interactions.	GTF2IRD2B GTF2IRD2	2.53e-05	4	72	2	21328569
Pubmed	Deletion and expression analysis of AZFa genes on the human Y chromosome revealed a major role for DBY in male infertility.	USP9Y KDM6A	2.53e-05	4	72	2	10767340
Pubmed	Proximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins.	EPS15L1 USP9X TJP2 CSPP1 CYFIP2	2.75e-05	169	72	5	31462741
Pubmed	Fragmentation of decorin, biglycan, lumican and keratocan is elevated in degenerate human meniscus, knee and hip articular cartilages compared with age-matched macroscopically normal and control tissues.	FMOD LUM	4.21e-05	5	72	2	18620607
Pubmed	The regulatory roles of small leucine-rich proteoglycans in extracellular matrix assembly.	FMOD LUM	4.21e-05	5	72	2	23331954
Pubmed	Lipid-Droplet Formation Drives Pathogenic Group 2 Innate Lymphoid Cells in Airway Inflammation.	IL1RL1 DGAT1	4.21e-05	5	72	2	32268121
Pubmed	Evaluation of candidate genes in a genome-wide association study of childhood asthma in Mexicans.	IL1RL1 CYFIP2	4.21e-05	5	72	2	19910030
Pubmed	Mechanism of blood-retinal barrier breakdown induced by HIV-1 (Review).	TJP2 MMP9	4.21e-05	5	72	2	24660027
Pubmed	Genes encoding proteoglycans are associated with the risk of anterior cruciate ligament ruptures.	FMOD LUM	4.21e-05	5	72	2	24552666
Pubmed	Novel QTLs for HDL levels identified in mice by controlling for Apoa2 allelic effects: confirmation of a chromosome 6 locus in a congenic strain.	HMGCR DGAT1	4.21e-05	5	72	2	14722362
Pubmed	Embryonic trafficking of gammadelta T cells to skin is dependent on E/P selectin ligands and CCR4.	SELE CCR4	6.31e-05	6	72	2	20368416
Pubmed	Complementary interplay between matrix metalloproteinase-9, vascular endothelial growth factor and osteoclast function drives endochondral bone formation.	SPI1 MMP9	6.31e-05	6	72	2	20142327
Pubmed	Small leucine-rich proteoglycans exhibit unique spatiotemporal expression profiles during cardiac valve development.	FMOD LUM	6.31e-05	6	72	2	24272803
Pubmed	Cytosolic GDH1 degradation restricts protein synthesis to sustain tumor cell survival following amino acid deprivation.	RNF213 KDM6A	8.82e-05	7	72	2	34269483
Pubmed	Multidimensional prognostic risk assessment identifies association between IL12B variation and surgery in Crohn's disease.	COL5A1 CACNA2D1	8.82e-05	7	72	2	23665963
Pubmed	Breaking down the barrier: the effects of HIV-1 on the blood-brain barrier.	TJP2 MMP9	8.82e-05	7	72	2	21641584
Pubmed	TDP2 protects transcription from abortive topoisomerase activity and is required for normal neural function.	CACNA2D1 TOP2A	8.82e-05	7	72	2	24658003
Pubmed	HIV-1 gp120 and drugs of abuse: interactions in the central nervous system.	TJP2 MMP9	1.17e-04	8	72	2	22591361
Pubmed	Genome-wide association of multiple complex traits in outbred mice by ultra-low-coverage sequencing.	PPARGC1A UNC13C	1.17e-04	8	72	2	27376238
Pubmed	JNK1/2-dependent phosphorylation of angulin-1/LSR is required for the exclusive localization of angulin-1/LSR and tricellulin at tricellular contacts in EpH4 epithelial sheet.	TJP2 MARVELD2	1.17e-04	8	72	2	24889144
Pubmed	Scavenger receptor CD36 mediates inhibition of cholesterol synthesis via activation of the PPARγ/PGC-1α pathway and Insig1/2 expression in hepatocytes.	PPARGC1A HMGCR	1.17e-04	8	72	2	24371122
Pubmed	Thrombin Enhanced Matrix Metalloproteinase-9 Expression and Migration of SK-N-SH Cells via PAR-1, c-Src, PYK2, EGFR, Erk1/2 and AP-1.	MMP9 F2R	1.17e-04	8	72	2	27181591
Pubmed	The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics.	EPS15L1 FAM120C SEC16A TOP2A	1.35e-04	125	72	4	29467281
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	EPS15L1 RPN1 USP9X SEC16A TJP2 KDM6A TOP2A	1.43e-04	549	72	7	38280479
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	AGBL4 CACNA2D1 ADCY4 EPS15L1 CORO2B RPN1 FAM120C USP9X SEC16A TJP2 CYFIP2	1.66e-04	1431	72	11	37142655
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	COL5A1 CACNA2D1 FAP RPN1 RNF213 HMGCR CERS6 LUM DCBLD2 DGAT1	1.78e-04	1201	72	10	35696571
Pubmed	The developmental regulation of peroxisome proliferator-activated receptor-gamma coactivator-1alpha expression in the liver is partially dissociated from the control of gluconeogenesis and lipid catabolism.	PPARGC1A HMGCR	1.88e-04	10	72	2	15178647
Pubmed	KSHV Viral Protein Kinase Interacts with USP9X to Modulate the Viral Lifecycle.	USP9X SEC16A	1.88e-04	10	72	2	36995092
Pubmed	The contribution of genetic factors to thrombotic and bleeding outcomes in coronary patients randomised to IIb/IIIa antagonists.	SELE MMP9	1.88e-04	10	72	2	12082590
Pubmed	Characterisation of the coding sequence and fine mapping of the human DFFRY gene and comparative expression analysis and mapping to the Sxrb interval of the mouse Y chromosome of the Dffry gene.	USP9X USP9Y	1.88e-04	10	72	2	9384609
Pubmed	Embryonic macrophages and microglia ablation alter the development of dorsal root ganglion sensory neurons in mouse embryos.	SPI1 NTRK3	2.30e-04	11	72	2	30252950
Pubmed	Defects in chondrocyte maturation and secondary ossification in mouse knee joint epiphyses due to Snorc deficiency.	MMP9 TOP2A	2.30e-04	11	72	2	28323137
Pubmed	Podocan, a novel small leucine-rich repeat protein expressed in the sclerotic glomerular lesion of experimental HIV-associated nephropathy.	FMOD LUM	2.30e-04	11	72	2	12796502
Pubmed	Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.	COL5A1 FMOD LUM MMP9	2.46e-04	146	72	4	27068509
Pubmed	Multi-locus interactions predict risk for post-PTCA restenosis: an approach to the genetic analysis of common complex disease.	SELE MMP9 IL5RA	2.67e-04	60	72	3	12082592
Pubmed	Loss of Usp9x disrupts cortical architecture, hippocampal development and TGFβ-mediated axonogenesis.	USP9X USP9Y	2.75e-04	12	72	2	23861879
Pubmed	Phenotypic analysis of mice lacking the Tmprss2-encoded protease.	MMP9 F2R	2.75e-04	12	72	2	16428450
Pubmed	Cofilin and Vangl2 cooperate in the initiation of planar cell polarity in the mouse embryo.	IFT88 TJP2	2.75e-04	12	72	2	23406901
Pubmed	Phenotypic annotation of the mouse X chromosome.	USP9X KDM6A ALG13	2.81e-04	61	72	3	20548051
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	USP9X SEC16A TJP2 CSPP1 CYFIP2 ALG13	3.29e-04	446	72	6	24255178
Pubmed	Endothelial Cyp26b1 restrains murine heart valve growth during development.	ADCY4 NTRK3 HMGCR F2R	3.73e-04	163	72	4	35364055
Pubmed	Maternal diabetes causes coordinated down-regulation of genes involved with lipid metabolism in the murine fetal heart.	PPARGC1A DGAT1	3.78e-04	14	72	2	18502258
Pubmed	Individual Limb Muscle Bundles Are Formed through Progressive Steps Orchestrated by Adjacent Connective Tissue Cells during Primary Myogenesis.	FMOD LUM	3.78e-04	14	72	2	32160556
Pubmed	Deubiquitinating enzymes: a new class of biological regulators.	USP9X USP9Y	4.36e-04	15	72	2	9827704
Pubmed	Evolutionary strata on the mouse X chromosome correspond to strata on the human X chromosome.	USP9X USP9Y	4.36e-04	15	72	2	14762062
Pubmed	DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization.	AKAP8 RPN1 USP9X SEC16A	4.88e-04	175	72	4	25756610
Pubmed	Chronic Alcohol Exposure and the Circadian Clock Mutation Exert Tissue-Specific Effects on Gene Expression in Mouse Hippocampus, Liver, and Proximal Colon.	PPARGC1A HMGCR MMP9	4.96e-04	74	72	3	26332085
Pubmed	Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning.	ADCY4 USH2A	4.98e-04	16	72	2	17567809
Pubmed	Interacting partners of macrophage-secreted cathepsin B contribute to HIV-induced neuronal apoptosis.	LUM MMP9	4.98e-04	16	72	2	26208400
Pubmed	Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia.	IL1RL1 MMP9 IL5RA TOP2A	5.31e-04	179	72	4	19074885
Pubmed	A strategy for modulation of enzymes in the ubiquitin system.	USP9X USP9Y	5.63e-04	17	72	2	23287719
Pubmed	Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.	PPARGC1A RPN1 USP9X RNF213	5.77e-04	183	72	4	23956138
Pubmed	A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM).	SELE COL5A1 MMP9 IL5RA	6.14e-04	186	72	4	20673868
Pubmed	Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes.	SELE COL5A1 MMP9 IL5RA	6.14e-04	186	72	4	20452482
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	EPS15L1 AKAP8 USP9X SEC16A TJP2 TOP2A	6.19e-04	503	72	6	16964243
Pubmed	A candidate gene approach to genetic prognostic factors of IgA nephropathy--a result of Polymorphism REsearch to DIstinguish genetic factors Contributing To progression of IgA Nephropathy (PREDICT-IgAN).	SELE PPARGC1A MMP9	6.23e-04	80	72	3	19420105
Pubmed	Ciliary Hedgehog signaling patterns the digestive system to generate mechanical forces driving elongation.	IFT88 ANO5	6.33e-04	18	72	2	34893605
Pubmed	Defining the membrane proteome of NK cells.	EPS15L1 AKAP8 RPN1 USP9X RNF213 CERS6 RETSAT LMBRD1 CYFIP2	6.72e-04	1168	72	9	19946888
Pubmed	An integrated genetic map of the pearl locus of mouse chromosome 13.	HMGCR F2R	7.06e-04	19	72	2	8828042
Pubmed	Single-cell atlas of early human brain development highlights heterogeneity of human neuroepithelial cells and early radial glia.	NTRK3 LUM	7.06e-04	19	72	2	33723434
Pubmed	Transcriptional fates of human-specific segmental duplications in brain.	GTF2IRD2B GTF2IRD2	7.06e-04	19	72	2	30228200
Pubmed	Systematic Affinity Purification Coupled to Mass Spectrometry Identified p62 as Part of the Cannabinoid Receptor CB2 Interactome.	RPN1 USP9X ATE1	7.19e-04	84	72	3	31616248
Interaction	TDRD3 interactions	FAM120C USP9X SEC16A TJP2 CSPP1 CYFIP2 ALG13	8.83e-06	212	70	7	int:TDRD3
Cytoband	Ensembl 112 genes in cytogenetic band chr2q24	FAP SCN7A CERS6	1.07e-03	127	72	3	chr2q24
Cytoband	Ensembl 112 genes in cytogenetic band chr5q13	HMGCR MARVELD2 F2R	1.80e-03	152	72	3	chr5q13
GeneFamily	Small leucine rich repeat proteoglycans	FMOD LUM	5.06e-04	12	51	2	573
GeneFamily	G protein-coupled receptors, Class A orphans	GPR3 GPR12 GPR15	1.39e-03	78	51	3	262
Coexpression	FLORIO_NEOCORTEX_BASAL_RADIAL_GLIA_UP	SELE PPARGC1A FMOD ZNF608 IL1RL1 MARVELD2 C7 JAML IL5RA	1.07e-06	384	72	9	M798
Coexpression	GSE11961_FOLLICULAR_BCELL_VS_MARGINAL_ZONE_BCELL_UP	GPR155 CACNA2D1 IFT88 MMP9 USP9Y MS4A7	1.88e-05	200	72	6	M9381
Coexpression	GSE32164_RESTING_DIFFERENTIATED_VS_ALTERNATIVELY_ACT_M2_MACROPHAGE_DN	COL5A1 AKAP8 RPN1 MMP9 F2R DGAT1	1.88e-05	200	72	6	M8524
CoexpressionAtlas	kidney_adult_RenalCapsule_top-relative-expression-ranked_100	FAP FMOD SLFN5 C7 LUM	9.94e-06	88	69	5	gudmap_kidney_adult_RenalCapsule_100
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL5A1 FAP FMOD IL1RL1 C7 LUM MMP9 F2R	1.10e-09	197	72	8	4cf4e9553397cd8dee883dbec24f41bec41aff99
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL5A1 FAP FMOD C7 LUM MMP9 F2R	2.79e-08	193	72	7	dc8e62df6121ee99b156aca6b1b3ae555739b6f2
ToppCell	Mesenchymal-matrix_fibroblast_1_cell\|World / Lineage, Cell type, age group and donor	COL5A1 CACNA2D1 FAP SCN7A UNC13C C7 LUM	2.79e-08	193	72	7	acad568621ed677031797b8c2e34dafea798d681
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL5A1 FAP FMOD C7 LUM MMP9 F2R	2.79e-08	193	72	7	e2ee077fd381bd906e6b4329f22e7d106e422a7f
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL5A1 CACNA2D1 FAP SCN7A UNC13C C7 LUM	2.89e-08	194	72	7	011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell	metastatic_Brain-Fibroblasts-FB-like_cells\|metastatic_Brain / Location, Cell class and cell subclass	COL5A1 FAP FMOD NTRK3 C7 LUM F2R	3.44e-08	199	72	7	12133087eae9f0e9b6c13a71e8187117768e64ce
ToppCell	metastatic_Brain-Fibroblasts\|metastatic_Brain / Location, Cell class and cell subclass	COL5A1 FAP FMOD NTRK3 C7 LUM F2R	3.44e-08	199	72	7	63eb2106bb6e2e33d020628583536c8d96662c84
ToppCell	Biopsy_Control_(H.)-Mesenchymal-Fibroblasts\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	COL5A1 FAP FMOD SCN7A C7 LUM GALNT16	3.56e-08	200	72	7	8d75ce89393df452defacf2ec9a5bd4b7708afbb
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Fibroblasts-4\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	COL5A1 FAP FMOD SCN7A C7 LUM F2R	3.56e-08	200	72	7	54b18c92daaa3b3368c0c46134b0c27e10c8dbb0
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Myeloid-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 CERS6 MMP9 JAML DGAT1 CYFIP2	2.28e-07	159	72	6	a6093b230afdd4d91870d289c6ac91d1856666a3
ToppCell	5'-Adult-Appendix-Hematopoietic-T_cells-Activated_CD8_T\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GPR155 IKZF3 APBA2 RNF213 SLFN5 JAML	2.74e-07	164	72	6	24fdea5113d92b96f56b06dd2449910a3c785e69
ToppCell	-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	COL5A1 SCN7A APBA2 C7 LUM F2R	3.75e-07	173	72	6	88be9182fbb1bc83531cd41e59ea57c112a21d54
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PPARGC1A CACNA2D1 GPR12 ALKAL1 UNC13C RGS7	3.88e-07	174	72	6	b7f5492ce8098f7eb0aef30ee558d00738d59d0e
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PPARGC1A CACNA2D1 GPR12 ALKAL1 UNC13C RGS7	3.88e-07	174	72	6	71730503be3d9c839c4c9e950145e2101d682a1c
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	PPARGC1A CACNA2D1 GPR12 ALKAL1 UNC13C RGS7	3.88e-07	174	72	6	ee8ac51fa0b426ad7b7453371bb79c8bf8c1d358
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PPARGC1A CACNA2D1 GPR12 ALKAL1 UNC13C RGS7	3.88e-07	174	72	6	cafe4d6b5f08d8888e9db6e196c66df991c03e7b
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL5A1 FAP FMOD SCN7A C7 LUM	4.29e-07	177	72	6	cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_3\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	COL5A1 CACNA2D1 FAP CORO2B C7 GALNT16	4.29e-07	177	72	6	3d955ea938a1d2fb1b6d68d4997fd454bd632dfc
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL5A1 FAP FMOD SCN7A C7 LUM	4.29e-07	177	72	6	db222faaecbe5600da39277243c4e7e764eb63c9
ToppCell	facs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Lymphocytic-T_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IKZF3 GPR15 CCR4 IL1RL1 DGAT1 CYFIP2	4.73e-07	180	72	6	5fdd10ffdf49f0e818f865ca095a3882b35c640e
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL5A1 ALKAL1 SCN7A LUM F2R GALNT16	4.89e-07	181	72	6	9c157de9d3403e092c907599f2a2c16db5b21131
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL5A1 ALKAL1 SCN7A LUM F2R GALNT16	4.89e-07	181	72	6	eea943fdcbef0bbaa8578f3296923e874893b405
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL5A1 ALKAL1 SCN7A LUM F2R GALNT16	5.22e-07	183	72	6	bc7dd6a40ec9c773d005c1a46f305d40cdd0a326
ToppCell	COVID-19-Heart-Fib_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL5A1 CACNA2D1 CORO2B SCN7A C7 F2R	5.56e-07	185	72	6	8f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL5A1 FAP FMOD SCN7A C7 LUM	5.74e-07	186	72	6	94d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL5A1 FAP FMOD SCN7A C7 LUM	5.74e-07	186	72	6	5473283fb95cee556b1f6934cf72169b676b5bcc
ToppCell	-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	COL5A1 FMOD SCN7A IL1RL1 C7 LUM	6.11e-07	188	72	6	038f48e8daaeb72716e975d22a6b004a90654960
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IKZF3 APBA2 RNF213 SLFN5 KDM6A CYFIP2	6.50e-07	190	72	6	d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL5A1 FAP FMOD SCN7A C7 LUM	6.70e-07	191	72	6	0fae1c2ef9f83ac7721d0a9d69455bf97eed9257
ToppCell	renal_papilla_nuclei-Adult_normal_reference\|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA2D1 ZNF608 UNC13C C7 USP9Y CYFIP2	6.90e-07	192	72	6	6c106b91e46eabbe686a52a65a9c94ad9cbe9390
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	COL5A1 FAP CORO2B SCN7A C7 LUM	6.90e-07	192	72	6	60b1312e84f6d6448365a952469c506c00b5fe93
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL5A1 FAP FMOD SCN7A C7 LUM	6.90e-07	192	72	6	b9e4585bea280ca0ae159f0c6a2bf7b88a15a6e6
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	IKZF3 APBA2 RNF213 SLFN5 USP9Y F2R	6.90e-07	192	72	6	ab88ea7723f0fa3b39611981c043445f27425404
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL5A1 FAP FMOD SCN7A C7 LUM	7.12e-07	193	72	6	b05361ffe111a38cfa26eb86e4ae62c15ac99b7b
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-T_cells-CD8_Tmem\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IKZF3 APBA2 RNF213 CCR4 F2R JAML	7.34e-07	194	72	6	9344556b375fd9267652cdca57b2cbd50a878a1e
ToppCell	Control-Fibroblasts-Intermediate_pathological_FB\|Control / group, cell type (main and fine annotations)	COL5A1 CACNA2D1 FAP SCN7A C7 LUM	7.34e-07	194	72	6	03a269f75a481ea54aea8e6444605db8d6df493d
ToppCell	21-Trachea-Mesenchymal-Mesenchyme_RSPO2+\|Trachea / Age, Tissue, Lineage and Cell class	COL5A1 FAP SCN7A UNC13C C7 LUM	7.34e-07	194	72	6	8fc98d2c9d94f3bc6292265e20ab71c4f1f37bb3
ToppCell	COVID-19-Heart-Fib_2\|Heart / Disease (COVID-19 only), tissue and cell type	COL5A1 FAP CORO2B SCN7A C7 LUM	7.34e-07	194	72	6	d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCell	21-Trachea-Mesenchymal\|Trachea / Age, Tissue, Lineage and Cell class	COL5A1 FAP SCN7A UNC13C C7 LUM	7.34e-07	194	72	6	749dd8113ef260e00facac09de9861d61725124a
ToppCell	COVID-19-Heart-Fib_1\|Heart / Disease (COVID-19 only), tissue and cell type	COL5A1 CORO2B SCN7A C7 LUM F2R	7.56e-07	195	72	6	f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	COL5A1 CACNA2D1 SCN7A UNC13C C7 LUM	7.56e-07	195	72	6	1cdf5f296029ae424d9dba42e86a6d111e4896e6
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL5A1 FAP FMOD SCN7A C7 LUM	7.56e-07	195	72	6	1236dc60288c7dd91868e86e9174a2dacd3b11b3
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL5A1 FMOD SCN7A C7 LUM F2R	7.79e-07	196	72	6	525d6c8a277364e624e7cc586275f8a891436b57
ToppCell	COPD-Stromal-Myofibroblast\|COPD / Disease state, Lineage and Cell class	COL5A1 FAP FMOD SCN7A C7 LUM	7.79e-07	196	72	6	af206bb5bbb8b604a6212acd79878bcc3d326cec
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL5A1 FAP FMOD SCN7A LUM F2R	7.79e-07	196	72	6	82fad623212d986a7fca3496faf3f8c8f5b83a11
ToppCell	IPF-Stromal-Myofibroblast\|World / Disease state, Lineage and Cell class	COL5A1 FAP FMOD SCN7A C7 LUM	7.79e-07	196	72	6	7fc9894ceb79dab9f0495acc84e2d6d0d1c69bb7
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL5A1 FAP FMOD SCN7A C7 LUM	7.79e-07	196	72	6	9737a5f006d37b549f281e1863aca558e1e4dc99
ToppCell	IPF-Stromal-Myofibroblast\|IPF / Disease state, Lineage and Cell class	COL5A1 FAP FMOD SCN7A C7 LUM	7.79e-07	196	72	6	2d0a48e49b3b37bb66e33e74c52915911e1f8a74
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL5A1 FAP FMOD SCN7A C7 LUM	7.79e-07	196	72	6	42e9828222a9663525d571633e8a454c30bfa7f8
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	COL5A1 CACNA2D1 SCN7A UNC13C C7 LUM	7.79e-07	196	72	6	1450cb69c5bf469e97c03bf1890f6f7c54165b8a
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD8+_T\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IKZF3 APBA2 RNF213 SLFN5 F2R CYFIP2	7.79e-07	196	72	6	0f3c7fd450aaa1f866b8558692534c0ea2a34e75
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD8+_T\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	IKZF3 APBA2 RNF213 SLFN5 F2R CYFIP2	7.79e-07	196	72	6	4e1f8828413896ab8a4ec92a89d6789e8e37e05a
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL5A1 FAP FMOD SCN7A LUM F2R	7.79e-07	196	72	6	85e5046f774537684e1443c0fc147d562b7068d0
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL5A1 ADCY4 IL1RL1 C7 LUM F2R	7.79e-07	196	72	6	12d9028f90c057c6e5cff00301793fa550e86c5a
ToppCell	COVID-19-Fibroblasts-Intermediate_pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	COL5A1 CACNA2D1 FAP SCN7A C7 LUM	8.02e-07	197	72	6	f1c8936986123a3151140c374fcd62d6705c530b
ToppCell	COPD-Stromal-Myofibroblast\|World / Disease state, Lineage and Cell class	COL5A1 FAP FMOD SCN7A C7 LUM	8.02e-07	197	72	6	d51f484b4e01ac64233950d0b97fa88825ea1dbb
ToppCell	PCW_13-14-Mesenchymal\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	COL5A1 CACNA2D1 SCN7A UNC13C C7 LUM	8.02e-07	197	72	6	73a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCell	COPD-Stromal\|COPD / Disease state, Lineage and Cell class	COL5A1 FAP FMOD SCN7A C7 LUM	8.02e-07	197	72	6	d5390d86acaa8c39f1da893e8d2271f9ed2951d7
ToppCell	COVID-19-Fibroblasts\|COVID-19 / group, cell type (main and fine annotations)	COL5A1 CACNA2D1 FAP SCN7A C7 LUM	8.02e-07	197	72	6	fb847f2277609c31fffcdf49517243ce0684facf
ToppCell	distal-mesenchymal-Alveolar_Fibroblast-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FAP FMOD SCN7A C7 LUM F2R	8.26e-07	198	72	6	7f728ca6d5317890c6fcde3ce6c10c0970d49a05
ToppCell	COVID-19-lung-Fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	COL5A1 CACNA2D1 FAP SCN7A C7 LUM	8.26e-07	198	72	6	df3de77216f5c5d6141ec44d01c56b942f611838
ToppCell	distal-1-mesenchymal-Alveolar_Fibroblast\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FAP FMOD SCN7A C7 LUM F2R	8.26e-07	198	72	6	6594c35ab203dc51462167c61807b0d49fa30fb2
ToppCell	Kidney-Leukocytes\|Kidney / Skin and Kidney Cells in Lupus Nephritis Patients.	IKZF3 SPI1 MMP9 JAML MS4A7 TOP2A	8.26e-07	198	72	6	4050553f292ce00d547bc79207d6b9a44f4db34f
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL5A1 FAP FMOD SCN7A C7 LUM	8.26e-07	198	72	6	f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCell	5'-Parenchyma_lung-Mesenchymal\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL5A1 FAP FMOD SCN7A C7 LUM	8.26e-07	198	72	6	aae663c6da70b6e716edeed50cc7d3962d78e697
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL5A1 FAP FMOD C7 LUM GALNT16	8.51e-07	199	72	6	103f657132e830a0e5efeb745afb4b77c208a1fa
ToppCell	Biopsy_Control_(H.)-Mesenchymal-Myofibroblasts\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	COL5A1 FAP FMOD SCN7A C7 LUM	8.51e-07	199	72	6	7a227c239afdaebcac84644d9b2653a5f1a4be71
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL5A1 FAP FMOD SCN7A C7 LUM	8.51e-07	199	72	6	4e128c705ad36fd840582848f278770f356fcc8b
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL5A1 FAP FMOD SCN7A C7 LUM	8.51e-07	199	72	6	a538da095ba996ee96e263442cf5b6ba9178f3d4
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL5A1 FAP FMOD SCN7A C7 LUM	8.51e-07	199	72	6	4032f03a4165f5f2a90ef1d8315cc743ce9075bb
ToppCell	distal-mesenchymal-Alveolar_Fibroblast-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL5A1 FAP FMOD SCN7A C7 LUM	8.51e-07	199	72	6	fb23ecce41e31e2cc01814e3c0add756f489561f
ToppCell	PCW_10-12-Mesenchymal\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	COL5A1 CACNA2D1 SCN7A UNC13C C7 LUM	8.51e-07	199	72	6	a09292de4c4447b8eee55d401808e43b817321cc
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL5A1 FAP FMOD SCN7A C7 LUM	8.51e-07	199	72	6	0019cfaa586a450c2e4952d1184a540561c8d0ba
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL5A1 FAP FMOD SCN7A C7 LUM	8.51e-07	199	72	6	66a79732caf2f04c09b4d9832377aa01ca477677
ToppCell	distal-mesenchymal-Alveolar_Fibroblast\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL5A1 FAP FMOD SCN7A C7 LUM	8.51e-07	199	72	6	655d07cf9a2fd9b945a2ed4f824cba0297de72a8
ToppCell	Biopsy_Other_PF-Mesenchymal-Myofibroblasts\|Biopsy_Other_PF / Sample group, Lineage and Cell type	COL5A1 FAP FMOD SCN7A C7 LUM	8.76e-07	200	72	6	e504570fd7eec1524c401b1cfa9d10822d80d994
ToppCell	cellseq-Mesenchymal-Fibroblastic\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL5A1 FAP FMOD SCN7A C7 LUM	8.76e-07	200	72	6	8978867bf69c830b1e48cac2ad6b512dbe60f149
ToppCell	Biopsy_Control_(H.)-Mesenchymal\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	COL5A1 FAP FMOD SCN7A C7 LUM	8.76e-07	200	72	6	01522ed0b68614b1ebdf190957d44a9d48a6c6e3
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-1\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	COL5A1 FAP FMOD SCN7A C7 LUM	8.76e-07	200	72	6	c3d4ce70ab51d74c9fe2f5864e52a4a9d7570e10
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_alveolar\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL5A1 FAP FMOD SCN7A C7 LUM	8.76e-07	200	72	6	8c62f05c6042f24287a73fbdf80ff4a56f7ff403
ToppCell	Parenchymal-10x5prime-Stromal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL5A1 FAP FMOD SCN7A C7 LUM	8.76e-07	200	72	6	2e525c0d9684e7a2275edb04e1addb6fc6a872e5
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-1-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL5A1 FAP FMOD SCN7A C7 LUM	8.76e-07	200	72	6	137f8f9d255c66336d4f8b44b2e3f3de721f2bf0
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL5A1 FAP FMOD SCN7A C7 LUM	8.76e-07	200	72	6	6e3d1ae0ef84d3075afa40129a41169996462672
ToppCell	356C-Fibroblasts\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL5A1 FAP FMOD SCN7A C7 LUM	8.76e-07	200	72	6	9c95329f0b26ff378de803030d4c28517b3adc85
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL5A1 FAP FMOD SCN7A C7 LUM	8.76e-07	200	72	6	6316c288022719b9e6c4332c5cb9041e1188d0e8
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated\|COVID-19_Mild / Disease, condition lineage and cell class	IKZF3 RNF213 SLFN5 USP9Y F2R CYFIP2	8.76e-07	200	72	6	2281debd86e5d92e8fe0397aec9ef670800f7471
ToppCell	tumor_Lung-Fibroblasts\|tumor_Lung / Location, Cell class and cell subclass	COL5A1 FAP FMOD SCN7A C7 LUM	8.76e-07	200	72	6	073a68b5ce232203ffee86342cba2a00d907e119
ToppCell	Parenchyma_COVID-19-Stromal-TX-Fibroblasts-1\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	COL5A1 FAP FMOD SCN7A C7 LUM	8.76e-07	200	72	6	25d3865aa2ced11a5ed40013e83b47d942fdf582
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL5A1 FAP FMOD SCN7A C7 LUM	8.76e-07	200	72	6	54806080b5e97859ee6a4a9b4f19e22021c218f5
ToppCell	367C-Fibroblasts\|367C / Donor, Lineage, Cell class and subclass (all cells)	COL5A1 FAP FMOD SCN7A C7 LUM	8.76e-07	200	72	6	c5aaa20c59b9f11b8abdf5de9e3fc54f4e6e39f7
ToppCell	Biopsy_IPF-Mesenchymal-Myofibroblasts\|Biopsy_IPF / Sample group, Lineage and Cell type	COL5A1 FAP FMOD SCN7A C7 LUM	8.76e-07	200	72	6	c2c6f687c49ba790174b27c7b8b084af30b34c86
ToppCell	PND07-28-samps-Myeloid-Macrophage-macrophage-A\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	ATP1B4 ADCY4 SPI1 RNF213 USP9Y	1.07e-06	112	72	5	d21cfcb04a27cc9fb74e0c2afa8a8cdfb886ae21
ToppCell	PBMC-Severe-Myeloid-Neutrophil-Neutrophil-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SELE SPI1 IL1RL1 MMP9 NUPR2	3.10e-06	139	72	5	fa0eedebf53317928022c3bed391ce99a2114f98
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-T-T_CD8-MAIT\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	IKZF3 APBA2 CCR4 JAML IL5RA	4.36e-06	149	72	5	f4bee5fdaaa4a1917e403de90e5a62353006df24
ToppCell	PND14-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IL1RL1 CERS6 JAML TOP2A ALG13	5.45e-06	156	72	5	8349604bd801e20d33770f7d8243598c3756302b
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Myeloid-mast_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 MMP9 JAML DGAT1 CYFIP2	5.62e-06	157	72	5	cca7f23485b9d1a1c96134b6ca85dc7dba0c0522
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 MMP9 JAML DGAT1 CYFIP2	5.62e-06	157	72	5	241c983fc3fc5c98113baf27e03ff0eede611bd8
ToppCell	Children_(3_yrs)-Mesenchymal-chondrocyte\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL5A1 FAP SCN7A C7 GALNT16	5.62e-06	157	72	5	f147e24f2ece82e1c54750868954d09b3c461804
ToppCell	droplet-Heart-nan-18m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 MMP9 JAML DGAT1 CYFIP2	5.80e-06	158	72	5	81a5a73090804d41429d297ba2462a842f39d380
ToppCell	droplet-Heart-nan-18m-Myeloid-cardiac_mast_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPI1 MMP9 JAML DGAT1 CYFIP2	5.80e-06	158	72	5	9596b7b0f6f5157a43d67d2e67fb75a2624a6bb9
Disease	coronary artery disease (is_implicated_in)	SELE HMGCR IL1RL1 LUM MMP9	4.41e-06	100	71	5	DOID:3393 (is_implicated_in)
Disease	Ehlers-Danlos syndrome classic type 1 (implicated_via_orthology)	COL5A1 LUM	1.71e-05	3	71	2	DOID:14720 (implicated_via_orthology)
Disease	adenoid cystic carcinoma (is_implicated_in)	NTRK3 KDM6A	5.68e-05	5	71	2	DOID:0080202 (is_implicated_in)
Disease	chronic obstructive pulmonary disease (is_marker_for)	PPARGC1A IL1RL1 MMP9 IL5RA	9.01e-05	97	71	4	DOID:3083 (is_marker_for)
Disease	peripheral neuropathy	NTRK3 SCN7A	1.19e-04	7	71	2	EFO_0003100
Disease	renal fibrosis (biomarker_via_orthology)	PPARGC1A MMP9	3.71e-04	12	71	2	DOID:0050855 (biomarker_via_orthology)
Disease	acute myeloid leukemia (implicated_via_orthology)	SPI1 TOP2A	3.71e-04	12	71	2	DOID:9119 (implicated_via_orthology)
Disease	Brain Ischemia	SELE CCR4 MMP9	4.14e-04	60	71	3	C0007786
Disease	Cerebral Ischemia	SELE CCR4 MMP9	4.14e-04	60	71	3	C0917798
Disease	Headache	CACNA2D1 TJP2 RNF213	5.01e-04	64	71	3	HP_0002315
Disease	alcohol use disorder (biomarker_via_orthology)	SPI1 MMP9	5.10e-04	14	71	2	DOID:1574 (biomarker_via_orthology)
Disease	membranous glomerulonephritis (biomarker_via_orthology)	C7 MMP9	5.10e-04	14	71	2	DOID:10976 (biomarker_via_orthology)
Disease	asthma (is_implicated_in)	HMGCR IL1RL1 MMP9 IL5RA	5.68e-04	157	71	4	DOID:2841 (is_implicated_in)
Disease	brain edema (biomarker_via_orthology)	MMP9 F2R	5.87e-04	15	71	2	DOID:4724 (biomarker_via_orthology)
Disease	myocardial infarction (biomarker_via_orthology)	PPARGC1A C7 MMP9 KDM6A	6.10e-04	160	71	4	DOID:5844 (biomarker_via_orthology)
Disease	Malignant Glioma	NTRK3 CCR4 TOP2A	6.51e-04	70	71	3	C0555198
Disease	mixed gliomas	NTRK3 CCR4 TOP2A	6.51e-04	70	71	3	C0259783
Disease	Huntington's disease (biomarker_via_orthology)	PPARGC1A MMP9	6.70e-04	16	71	2	DOID:12858 (biomarker_via_orthology)
Disease	severe acute respiratory syndrome, COVID-19	PPARGC1A CACNA2D1 RPN1 USP9X UNC13C SLFN5	7.29e-04	447	71	6	EFO_0000694, MONDO_0100096
Disease	total blood protein measurement	CACNA2D1 DNAH3 EPS15L1 IKZF3 SPI1 SEC16A	7.46e-04	449	71	6	EFO_0004536
Disease	esophagus squamous cell carcinoma (is_marker_for)	FAP MMP9 KDM6A	7.66e-04	74	71	3	DOID:3748 (is_marker_for)
Disease	Asthma	IKZF3 IL1RL1 MMP9	9.60e-04	80	71	3	C0004096
Disease	alpha-tocopherol measurement	CACNA2D1 USH2A	1.05e-03	20	71	2	EFO_0007898
Disease	hyperglycemia (biomarker_via_orthology)	PPARGC1A MMP9	1.16e-03	21	71	2	DOID:4195 (biomarker_via_orthology)
Disease	Glioma	NTRK3 CCR4 TOP2A	1.22e-03	87	71	3	C0017638
Disease	carotid artery disease (is_implicated_in)	LUM MMP9	1.28e-03	22	71	2	DOID:3407 (is_implicated_in)
Disease	asthma exacerbation measurement	CACNA2D1 IKZF3 IL1RL1	1.48e-03	93	71	3	EFO_0007614
Disease	nephrotic syndrome (biomarker_via_orthology)	PPARGC1A DGAT1	1.52e-03	24	71	2	DOID:1184 (biomarker_via_orthology)
Disease	hearing impairment	TJP2 MARVELD2 USH2A	1.72e-03	98	71	3	C1384666
Disease	pancreatic cancer (is_marker_for)	CCR4 LUM MMP9	1.88e-03	101	71	3	DOID:1793 (is_marker_for)
Disease	chronic kidney disease (biomarker_via_orthology)	HMGCR DGAT1	2.07e-03	28	71	2	DOID:784 (biomarker_via_orthology)
Disease	cortex volume change measurement, age at assessment	UNC13C LMBRD1	2.07e-03	28	71	2	EFO_0008007, EFO_0021500
Disease	primary biliary cholangitis (biomarker_via_orthology)	PPARGC1A MMP9	2.07e-03	28	71	2	DOID:12236 (biomarker_via_orthology)
Disease	amyotrophic lateral sclerosis (is_marker_for)	PPARGC1A MMP9	2.22e-03	29	71	2	DOID:332 (is_marker_for)
Disease	neutrophil percentage of granulocytes	EPS15L1 IKZF3 RPN1 IL5RA	2.25e-03	228	71	4	EFO_0007994

Protein segments in the cluster

Peptide	Gene	Start	Entry
NSLYESYYKQVDPAY	EPS15L1	16	Q9UBC2
YLYRAEPDYETSGVY	ALG13	796	Q9NP73
FTSDIIPRLVYYYAY	ANO5	751	Q75V66
IPRLVYYYAYSTNAT	ANO5	756	Q75V66
YRPSYSYDYEFDLGS	AKAP8	146	O43823
RLYYNTRECSTPAYY	ALKAL1	96	Q6UXT8
SLIADYTYPSIYTYA	GPR12	271	P47775
TSVYLDYYYATSPNS	GPR15	6	P49685
YDYYLPDEQATIQYS	A2ML1	1436	A8K2U0
FYETYYSLSQQYPLL	ADCY4	16	Q8NFM4
GITYYIRYCPEDDSY	APBA2	96	Q99767
LDESIYSNYYLYESI	CCR4	11	P51679
VSYPDNLTYRDLYYF	DGAT1	241	O75907
SISYYPESASFDLRY	ATP1B4	281	Q9UN42
DLYITYDKYYQTPRL	ATG3	201	Q9NT62
DEYKQYYYEARPSAI	GALNT16	376	Q8N428
DRQLAEEYLYRYGYT	MMP9	41	P14780
LRSQQSTYYDPYDPY	FMOD	31	Q06828
SRDVYSTDYYRLFNP	NTRK3	701	Q16288
ALYQTTYPEYLQYIY	GPR155	156	Q7Z3F1
PSSLQYLPYRDYNYS	HMGCR	506	P04035
RQIEDTVLYGYYTLY	LMBRD1	91	Q9NUN5
LEDYPKALSAYQRYY	KDM6A	106	O15550
SEMDYLSSLPYSEYY	MS4A7	151	Q9GZW8
PISYEEELYDCLDYY	NUPR2	21	A6NF83
PLATNYRTPYDDAYY	CSPP1	541	Q1MSJ5
YPLYHSVYETYELVE	FOLH1B	241	Q9HBA9
IEYLNSILSYSPSYY	SELE	56	P16581
EYVLYPLDLYNDSAY	CYFIP2	686	Q96F07
TVDRYLSLYNALTYY	GPR3	131	P46089
DVLNETLLEGYYAYY	F2R	256	P25116
SPYSRRPRYDSYEEY	PPARGC1A	626	Q9UBK2
AYDRYVAIYNPLLYS	OR5T1	131	Q8NG75
LYDAYVVYPRNYKSS	IL1RL1	376	Q01638
TDAPEDTQYFLYYRY	IL5RA	161	Q01344
LYSGYNDYNPIYDIE	IFT88	16	Q13099
RYYEISTEKPYLSYL	CORO2B	296	Q9UQ03
PSESDLERYYYYLTN	DNAH3	226	Q8TD57
DYSLALVLPTYSFYY	CACNA2D1	616	P54289
YRPDQVSAVDSYYYD	DNASE1	106	P24855
LYDYSAYRRLIDQYG	C7	286	P10643
DSEYALYNIPSYYSS	FAM120C	261	Q9NX05
REEDIYQFAYCYPYT	AGBL4	156	Q5VU57
YQPLTTDLHYYYILE	CERS6	171	Q6ZMG9
NLDENYYDPYYDPTS	COL5A1	411	P20908
TSGQYYDYDFPLSIY	LUM	16	P51884
TYSEKVEEYNLRYSY	MARVELD2	171	Q8N4S9
NCVSSVYLYYDPDYS	ATE1	361	O95260
VYLYYDPDYSFLSLG	ATE1	366	O95260
SYATQTQSVPEYYDY	KHDRBS2	291	Q5VWX1
YYVSAYRILYSDDGQ	DCBLD2	376	Q96PD2
YYPSREQERISYLYN	DCST2	531	Q5T1A1
YELDSQYGSLLYYTE	GTF2IRD2	696	Q86UP8
YELDSQYGSLLYYTE	GTF2IRD2B	696	Q6EKJ0
PYSYSREYNEYENIK	IKZF3	86	Q9UKT9
LHLPSTNYYVYYDTD	RETSAT	401	Q6NUM9
IYTTEDQYPYSIQYF	USH2A	1096	O75445
AYSYTYELRPYLDLL	USP9X	2326	Q93008
DSLLSYTEQYLEYDP	RGS7	281	P49802
LYYEPYYSRVVLESG	TRGV1	66	A0A0A0MS02
KDEYVLYYYSNLSVP	JAML	66	Q86YT9
LPSYEYLYNLGDQYA	RPN1	336	P04843
SRASLVSVYNSYPYY	NKX3-1	206	Q99801
DLYQRQTHEYYPYLS	SPI1	26	P17947
YSYYGDEQYPRTINI	FAP	236	Q12884
LEEVYDYLYQPSYRK	RNF213	1271	Q63HN8
AYDPDYERAYSPEYR	TJP2	256	Q9UDY2
YQPDLSYNLALAYYS	TTC30B	186	Q8N4P2
TTLDSDVYTEPYYYK	UNC13C	846	Q8NB66
LYYQDVYSLYEPRYR	SEC16A	1186	O15027
VAYSYTYELRPYLDL	USP9Y	2326	O00507
PEDYLYGQTTTYLTY	TOP2A	681	P11388
YQPDLSYNLALAYYS	TTC30A	186	Q86WT1
ATSPAYRQQYEKYYE	ZNF608	1096	Q9ULD9
PYYIRETENFYYLEG	SCN7A	286	Q01118
VYSSYLQIYPESYNF	SLFN5	506	Q08AF3