Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR51T1 NPBWR1 NPBWR2 PRLHR DRD2 OXER1 DRD3 HTR2B MLNR MC1R MC2R MC4R MC5R KIR2DS2 NMUR2 PTCH1 GPR101 GRM4 IL18R1 CLEC12A OR52N1 EDNRA FFAR4 OPRK1 OR52E2 CXCR5 OR6F1 ADORA1 ADORA2A OR52K1 OR2A12 IGF2R OR52A5 ACKR3 OR52D1 OR52N2 OR5H8 AGTR2 OR52E4 SCTR ADGRE5 TACR1 TAS2R60 OR51G1 KIR2DS1 OR52K2 KIR2DS4 KIR2DS5 KIR3DS1 ALK OR52B2 GPR45

5.06e-26135313752GO:0004888
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR51T1 NPBWR1 NPBWR2 PRLHR DRD2 OXER1 DRD3 HTR2B MLNR MC1R MC2R MC4R MC5R NMUR2 GPR101 GRM4 OR52N1 EDNRA FFAR4 OPRK1 OR52E2 CXCR5 OR6F1 ADORA1 ADORA2A OR52K1 OR2A12 OR52A5 ACKR3 OR52D1 OR52N2 OR5H8 AGTR2 OR52E4 SCTR ADGRE5 TACR1 TAS2R60 OR51G1 OR52K2 OR52B2 GPR45

3.34e-2488413742GO:0004930
GeneOntologyMolecularFunctionG protein-coupled peptide receptor activity

NPBWR1 NPBWR2 PRLHR MLNR MC1R MC2R MC4R MC5R NMUR2 EDNRA OPRK1 AGTR2 SCTR TACR1

3.98e-1313313714GO:0008528
GeneOntologyMolecularFunctionpeptide receptor activity

NPBWR1 NPBWR2 PRLHR MLNR MC1R MC2R MC4R MC5R NMUR2 EDNRA OPRK1 AGTR2 SCTR TACR1

8.14e-1314013714GO:0001653
GeneOntologyMolecularFunctionmelanocortin receptor activity

MC1R MC2R MC4R MC5R

3.15e-0861374GO:0004977
GeneOntologyMolecularFunctionneuropeptide binding

NPBWR1 NPBWR2 PRLHR MC4R NMUR2 OPRK1

1.82e-07371376GO:0042923
GeneOntologyMolecularFunctionolfactory receptor activity

OR51T1 OR52N1 OR52E2 OR6F1 OR52K1 OR2A12 OR52A5 OR52D1 OR52N2 OR5H8 OR52E4 OR51G1 OR52K2 OR52B2

1.64e-0643113714GO:0004984
GeneOntologyMolecularFunctionneuropeptide receptor activity

NPBWR1 NPBWR2 PRLHR MC2R NMUR2 TACR1

1.65e-06531376GO:0008188
GeneOntologyMolecularFunctionG protein-coupled opioid receptor activity

NPBWR1 NPBWR2 OPRK1

1.08e-0571373GO:0004985
GeneOntologyMolecularFunctionhormone binding

PRLHR MLNR MC1R MC4R MC5R SCTR

7.74e-051031376GO:0042562
GeneOntologyMolecularFunctiondopamine neurotransmitter receptor activity, coupled via Gi/Go

DRD2 DRD3

1.40e-0431372GO:0001591
GeneOntologyMolecularFunctionmelanocyte-stimulating hormone receptor activity

MC1R MC4R

1.40e-0431372GO:0004980
GeneOntologyMolecularFunctionG-protein alpha-subunit binding

DRD2 HTR2B RGS22 IGF2R

2.13e-04431374GO:0001965
GeneOntologyMolecularFunctionserine-type endopeptidase activity

PRSS54 RHBDD1 PRTN3 RHBDF2 TMPRSS6 TYSND1 ADAM17

3.43e-041901377GO:0004252
GeneOntologyMolecularFunctionpeptide binding

NPBWR1 NPBWR2 PRLHR MC4R NMUR2 FFAR4 OPRK1 SLC7A8 SCTR

3.55e-043181379GO:0042277
GeneOntologyMolecularFunctiondopamine neurotransmitter receptor activity

DRD2 DRD3

4.61e-0451372GO:0004952
GeneOntologyMolecularFunctionserine-type peptidase activity

PRSS54 RHBDD1 PRTN3 RHBDF2 TMPRSS6 TYSND1 ADAM17

5.74e-042071377GO:0008236
GeneOntologyMolecularFunctionserine hydrolase activity

PRSS54 RHBDD1 PRTN3 RHBDF2 TMPRSS6 TYSND1 ADAM17

6.61e-042121377GO:0017171
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN11A SCN3A SCN10A

7.32e-04261373GO:0005248
GeneOntologyMolecularFunctionG protein-coupled adenosine receptor activity

ADORA1 ADORA2A

9.59e-0471372GO:0001609
GeneOntologyMolecularFunctionimmune receptor activity

IL18R1 CXCR5 ACKR3 KIR2DS4 KIR2DS5 KIR3DS1

9.80e-041651376GO:0140375
GeneOntologyMolecularFunctionC-X-C chemokine receptor activity

CXCR5 ACKR3

1.27e-0381372GO:0016494
GeneOntologyMolecularFunctionmonoatomic ion channel activity

LRRC8C ANO9 SCN11A NMUR2 SLC26A8 MLC1 SCN3A SCN10A KCNMB4 KCNT1

1.28e-0345913710GO:0005216
GeneOntologyMolecularFunctionheterotrimeric G-protein binding

DRD2 ADORA1

1.63e-0391372GO:0032795
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

OR51T1 NPBWR1 NPBWR2 SCN11A PRLHR DRD2 OXER1 DRD3 HTR2B MLNR MC1R MC2R MC4R MC5R DGKE NMUR2 GPR101 GRM4 OR52N1 EDNRA FFAR4 OPRK1 OR52E2 CXCR5 GPR180 OR6F1 ADORA1 ADORA2A TGM2 OR52K1 OR2A12 IGF2R OR52A5 ACKR3 OR52D1 OR52N2 OR5H8 AGTR2 OR52E4 SCTR ADGRE5 TACR1 TAS2R60 OR51G1 OR52K2 ALK OR52B2 GPR45

4.50e-22139513948GO:0007186
GeneOntologyBiologicalProcessadenylate cyclase-modulating G protein-coupled receptor signaling pathway

DRD2 OXER1 DRD3 MC1R MC2R MC4R MC5R GPR101 GRM4 EDNRA FFAR4 OPRK1 ADORA1 ADORA2A SCTR ADGRE5

1.01e-1028613916GO:0007188
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR51T1 SCN11A OR52N1 FFAR4 OR52E2 OR6F1 ADORA1 OR52K1 OR2A12 OR52A5 OR52D1 OR52N2 OR5H8 SCN10A OR52E4 TAS2R60 OR51G1 OR52K2 OR52B2

1.38e-0858213919GO:0050906
GeneOntologyBiologicalProcessdetection of stimulus

OR51T1 SCN11A OR52N1 FFAR4 OR52E2 OR6F1 ADORA1 OR52K1 OR2A12 OR52A5 OR52D1 OR52N2 OR5H8 SCN10A OR52E4 KCNMB4 TACR1 TAS2R60 OR51G1 OR52K2 OR52B2

1.65e-0872213921GO:0051606
GeneOntologyBiologicalProcesssensory perception

OR51T1 SCN11A DRD2 MC1R NMUR2 OR52N1 FFAR4 OPRK1 OR52E2 OR6F1 ADORA1 ADORA2A COL18A1 OR52K1 OR2A12 OR52A5 OR52D1 OR52N2 OR5H8 SCN10A OR52E4 TAS2R60 OR51G1 OR52K2 OR52B2

4.91e-08107213925GO:0007600
GeneOntologyBiologicalProcessadenylate cyclase-activating G protein-coupled receptor signaling pathway

DRD2 DRD3 MC1R MC2R MC4R MC5R GPR101 FFAR4 ADORA2A SCTR ADGRE5

7.18e-0819113911GO:0007189
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR51T1 OR52N1 FFAR4 OR52E2 OR6F1 OR52K1 OR2A12 OR52A5 OR52D1 OR52N2 OR5H8 OR52E4 KCNMB4 TAS2R60 OR51G1 OR52K2 OR52B2

9.27e-0852413917GO:0009593
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR51T1 DRD2 OR52N1 FFAR4 OR52E2 OR6F1 OR52K1 OR2A12 OR52A5 OR52D1 OR52N2 OR5H8 OR52E4 TAS2R60 OR51G1 OR52K2 OR52B2

1.71e-0754713917GO:0007606
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR51T1 OR52N1 FFAR4 OR52E2 OR6F1 OR52K1 OR2A12 OR52A5 OR52D1 OR52N2 OR5H8 OR52E4 TAS2R60 OR51G1 OR52K2 OR52B2

1.82e-0748513916GO:0050907
GeneOntologyBiologicalProcessphospholipase C-activating G protein-coupled receptor signaling pathway

DRD2 DRD3 HTR2B NMUR2 EDNRA FFAR4 OPRK1 TGM2 TACR1

2.96e-071331399GO:0007200
GeneOntologyBiologicalProcesssensory perception of smell

OR51T1 DRD2 OR52N1 OR52E2 OR6F1 OR52K1 OR2A12 OR52A5 OR52D1 OR52N2 OR5H8 OR52E4 OR51G1 OR52K2 OR52B2

5.98e-0746513915GO:0007608
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR51T1 OR52N1 OR52E2 OR6F1 OR52K1 OR2A12 OR52A5 OR52D1 OR52N2 OR5H8 OR52E4 OR51G1 OR52K2 OR52B2

1.37e-0643213914GO:0050911
GeneOntologyBiologicalProcessadenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

DRD2 OXER1 DRD3 GRM4 EDNRA OPRK1 ADORA1

1.87e-06861397GO:0007193
GeneOntologyBiologicalProcessregulation of behavior

DRD2 DRD3 HTR2B MC1R MC4R OPRK1 ADORA1 ADORA2A

2.52e-061281398GO:0050795
GeneOntologyBiologicalProcesssecretion

RHBDD1 SCN11A DRD2 DRD3 RHBDF2 MC4R MYO18A SYT9 NMUR2 GRM4 EDNRA FFAR4 OPRK1 EFR3A ADORA1 ADORA2A TGM2 AGTR2 TMEM132A KCNMB4 ADAM17 TACR1 OC90

6.96e-06122113923GO:0046903
GeneOntologyBiologicalProcessrenal system process

SCN11A DRD2 EDNRA ADORA1 ADORA2A AGTR2 SCTR TACR1

7.78e-061491398GO:0003014
GeneOntologyBiologicalProcesssignal release

DRD2 DRD3 MC4R SYT9 GRM4 FFAR4 OPRK1 EFR3A ADORA1 ADORA2A TGM2 AGTR2 TMEM132A KCNMB4 ADAM17 TACR1

8.67e-0665313916GO:0023061
GeneOntologyBiologicalProcessfeeding behavior

PRLHR DRD2 MC1R MC4R NMUR2 OPRK1 ADORA2A TACR1

1.43e-051621398GO:0007631
GeneOntologyBiologicalProcesscatecholamine secretion

DRD2 DRD3 OPRK1 ADORA2A TGM2 AGTR2

1.56e-05791396GO:0050432
GeneOntologyBiologicalProcesscarboxylic acid transport

LRRC8C DRD2 DRD3 NMUR2 MFSD12 SLC7A8 ADORA1 ADORA2A SLC26A8 AGTR2 ABCD2 OC90

2.23e-0541013912GO:0046942
GeneOntologyBiologicalProcessorganic acid transport

LRRC8C DRD2 DRD3 NMUR2 MFSD12 SLC7A8 ADORA1 ADORA2A SLC26A8 AGTR2 ABCD2 OC90

2.34e-0541213912GO:0015849
GeneOntologyBiologicalProcessresponse to pain

SCN11A NMUR2 SCN3A SCN10A TACR1

2.37e-05511395GO:0048265
GeneOntologyBiologicalProcessbehavior

SCN11A PRLHR DRD2 DRD3 HTR2B MC1R MC4R NMUR2 GRM4 ZZEF1 OPRK1 ADORA1 ADORA2A SCN3A AGTR2 SCN10A TACR1 ALK

3.12e-0589113918GO:0007610
GeneOntologyBiologicalProcessphosphatidylinositol biosynthetic process

PIGB HTR2B DGKE EFR3A PIK3R4 MTMR14 PIGO

3.17e-051321397GO:0006661
GeneOntologyBiologicalProcesssynaptic transmission, glutamatergic

DRD2 DRD3 GRM4 ZZEF1 CNIH3 ADORA1 ADORA2A

3.17e-051321397GO:0035249
GeneOntologyBiologicalProcesseating behavior

MC4R NMUR2 OPRK1 ADORA2A TACR1

3.75e-05561395GO:0042755
GeneOntologyBiologicalProcessicosanoid secretion

DRD2 DRD3 NMUR2 AGTR2 OC90

3.75e-05561395GO:0032309
GeneOntologyBiologicalProcessresponse to amine

DRD2 DRD3 HTR2B EDNRA ADORA2A

4.45e-05581395GO:0014075
GeneOntologyBiologicalProcesscellular response to serotonin

HTR2B TGM2

4.51e-0521392GO:1904015
GeneOntologyBiologicalProcessresponse to serotonin

HTR2B TGM2

4.51e-0521392GO:1904014
GeneOntologyBiologicalProcessorganic anion transport

SLC17A2 LRRC8C DRD2 DRD3 NMUR2 MFSD12 SLC7A8 ADORA1 ADORA2A SLC26A8 AGTR2 ABCD2 OC90

4.68e-0551513913GO:0015711
GeneOntologyBiologicalProcesscatecholamine transport

DRD2 DRD3 OPRK1 ADORA2A TGM2 AGTR2

4.74e-05961396GO:0051937
GeneOntologyBiologicalProcessregulation of dopamine receptor signaling pathway

DRD2 DRD3 ALK

4.75e-05111393GO:0060159
GeneOntologyBiologicalProcessregulation of circadian sleep/wake cycle, sleep

DRD2 DRD3 ADORA1 ADORA2A

5.40e-05311394GO:0045187
GeneOntologyBiologicalProcessregulation of cytokinesis

DRD2 DRD3 BIRC6 PIK3R4 CXCR5 ATXN10

5.63e-05991396GO:0032465
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

HTR2B MC1R MC2R MC5R AGTR2

5.68e-05611395GO:0007187
GeneOntologyBiologicalProcessbehavioral response to pain

SCN11A SCN3A SCN10A TACR1

6.13e-05321394GO:0048266
GeneOntologyBiologicalProcessregulation of cell division

DRD2 DRD3 HTR2B PTCH1 BIRC6 PIK3R4 CXCR5 ATXN10

6.70e-052011398GO:0051302
GeneOntologyBiologicalProcesscircadian sleep/wake cycle, sleep

DRD2 DRD3 ADORA1 ADORA2A

6.94e-05331394GO:0050802
GeneOntologyBiologicalProcesscellular response to dopamine

DRD2 DRD3 HTR2B TGM2 ALK

7.16e-05641395GO:1903351
GeneOntologyBiologicalProcesssensory perception of pain

SCN11A MC1R NMUR2 OPRK1 ADORA1 SCN10A

7.83e-051051396GO:0019233
GeneOntologyBiologicalProcessG protein-coupled opioid receptor signaling pathway

NPBWR1 NPBWR2 OPRK1

8.15e-05131393GO:0038003
GeneOntologyBiologicalProcessnegative regulation of synaptic transmission, glutamatergic

DRD2 DRD3 ADORA1

8.15e-05131393GO:0051967
GeneOntologyBiologicalProcessresponse to dopamine

DRD2 DRD3 HTR2B TGM2 ALK

8.31e-05661395GO:1903350
GeneOntologyBiologicalProcessregulation of circadian sleep/wake cycle

DRD2 DRD3 ADORA1 ADORA2A

8.79e-05351394GO:0042749
GeneOntologyBiologicalProcessregulation of catecholamine secretion

DRD2 DRD3 OPRK1 ADORA2A AGTR2

8.93e-05671395GO:0050433
GeneOntologyBiologicalProcesscellular response to monoamine stimulus

DRD2 DRD3 HTR2B TGM2 ALK

9.59e-05681395GO:0071868
GeneOntologyBiologicalProcesscellular response to catecholamine stimulus

DRD2 DRD3 HTR2B TGM2 ALK

9.59e-05681395GO:0071870
GeneOntologyBiologicalProcesssecretion by cell

SCN11A DRD2 DRD3 RHBDF2 MC4R MYO18A SYT9 GRM4 FFAR4 OPRK1 EFR3A ADORA1 ADORA2A TGM2 AGTR2 TMEM132A KCNMB4 ADAM17 TACR1

9.72e-05106413919GO:0032940
GeneOntologyBiologicalProcessarachidonate secretion

DRD2 DRD3 NMUR2 OC90

9.84e-05361394GO:0050482
GeneOntologyBiologicalProcesscircadian sleep/wake cycle process

DRD2 DRD3 ADORA1 ADORA2A

9.84e-05361394GO:0022410
GeneOntologyBiologicalProcessarachidonate transport

DRD2 DRD3 NMUR2 OC90

9.84e-05361394GO:1903963
GeneOntologyBiologicalProcessregulation of blood volume by renin-angiotensin

DRD3 AGTR2 TACR1

1.03e-04141393GO:0002016
GeneOntologyBiologicalProcessregulation of systemic arterial blood pressure by renin-angiotensin

DRD3 NOX1 AGTR2 TACR1

1.10e-04371394GO:0003081
GeneOntologyBiologicalProcesssensory perception of temperature stimulus

SCN11A OPRK1 ADORA1 SCN10A

1.22e-04381394GO:0050951
GeneOntologyBiologicalProcesspositive regulation of MAPK cascade

DRD2 DRD3 HTR2B GPR101 GRM4 EDNRA FFAR4 OPRK1 ADORA1 NOX1 ACKR3 MAP4K1 ADAM17

1.32e-0457113913GO:0043410
GeneOntologyBiologicalProcessicosanoid transport

DRD2 DRD3 NMUR2 AGTR2 OC90

1.34e-04731395GO:0071715
GeneOntologyBiologicalProcessresponse to catecholamine

DRD2 DRD3 HTR2B TGM2 ALK

1.34e-04731395GO:0071869
GeneOntologyBiologicalProcessmonoamine transport

DRD2 DRD3 OPRK1 ADORA2A TGM2 AGTR2

1.36e-041161396GO:0015844
GeneOntologyBiologicalProcesslong-chain fatty acid transport

DRD2 DRD3 NMUR2 ABCD2 OC90

1.43e-04741395GO:0015909
GeneOntologyBiologicalProcessresponse to monoamine

DRD2 DRD3 HTR2B TGM2 ALK

1.43e-04741395GO:0071867
GeneOntologyBiologicalProcesssleep

DRD2 DRD3 ADORA1 ADORA2A

1.50e-04401394GO:0030431
GeneOntologyBiologicalProcessresponse to amphetamine

DRD2 DRD3 EDNRA ADORA2A

1.50e-04401394GO:0001975
GeneOntologyBiologicalProcessphosphatidylinositol metabolic process

PIGB HTR2B DGKE EFR3A PIK3R4 MTMR14 PIGO

1.56e-041701397GO:0046488
GeneOntologyBiologicalProcessdopamine secretion

DRD2 DRD3 OPRK1 TGM2

1.65e-04411394GO:0014046
GeneOntologyBiologicalProcessregulation of lipid catabolic process

TYSND1 ADORA1 SCTR ABCD2 ALK

1.84e-04781395GO:0050994
GeneOntologyBiologicalProcessneuropeptide signaling pathway

NPBWR1 NPBWR2 PRLHR MC2R NMUR2 OPRK1

1.96e-041241396GO:0007218
GeneOntologyBiologicalProcessregulation of systemic arterial blood pressure

DRD2 DRD3 ADORA1 NOX1 AGTR2 TACR1

1.96e-041241396GO:0003073
GeneOntologyBiologicalProcesscircadian sleep/wake cycle

DRD2 DRD3 ADORA1 ADORA2A

1.99e-04431394GO:0042745
GeneOntologyBiologicalProcessregulation of amine transport

DRD2 DRD3 OPRK1 ADORA1 ADORA2A AGTR2

2.04e-041251396GO:0051952
GeneOntologyBiologicalProcessregulation of synaptic transmission, GABAergic

DRD2 ADORA1 ADORA2A TACR1

2.37e-04451394GO:0032228
GeneOntologyBiologicalProcessnegative regulation of dopamine receptor signaling pathway

DRD2 DRD3

2.68e-0441392GO:0060160
GeneOntologyBiologicalProcessresponse to alcohol

AANAT SCN11A DRD2 DRD3 PTCH1 OPRK1 MLC1 MAP4K1 TACR1

2.71e-043121399GO:0097305
GeneOntologyBiologicalProcessexport from cell

SCN11A DRD2 DRD3 RHBDF2 MC4R MYO18A SYT9 GRM4 FFAR4 OPRK1 EFR3A ADORA1 ADORA2A TGM2 AGTR2 TMEM132A KCNMB4 ADAM17 TACR1

2.73e-04115313919GO:0140352
GeneOntologyBiologicalProcessfatty acid transport

DRD2 DRD3 NMUR2 AGTR2 ABCD2 OC90

2.75e-041321396GO:0015908
GeneOntologyBiologicalProcesssmooth muscle contraction

SCN11A DRD2 HTR2B NMUR2 EDNRA TACR1

2.86e-041331396GO:0006939
GeneOntologyBiologicalProcessprepulse inhibition

DRD2 DRD3 ADORA2A

3.14e-04201393GO:0060134
GeneOntologyBiologicalProcessamine transport

DRD2 DRD3 OPRK1 ADORA1 ADORA2A AGTR2

3.35e-041371396GO:0015837
GeneOntologyBiologicalProcessG protein-coupled receptor internalization

DRD2 DRD3 HTR2B

3.64e-04211393GO:0002031
GeneOntologyBiologicalProcessregulation of systemic arterial blood pressure by hormone

DRD3 NOX1 AGTR2 TACR1

3.86e-04511394GO:0001990
GeneOntologyBiologicalProcessregulation of synaptic transmission, glutamatergic

DRD2 DRD3 GRM4 ADORA1 ADORA2A

3.97e-04921395GO:0051966
GeneOntologyBiologicalProcessphenol-containing compound metabolic process

DRD2 DRD3 MC1R MFSD12 EDNRA AGTR2

4.06e-041421396GO:0018958
GeneOntologyBiologicalProcesscirculatory system process

SCN11A DRD2 DRD3 HTR2B EDNRA SLC7A8 ADORA1 ADORA2A NOX1 SCN3A AGTR2 SCN10A KCNMB4 TACR1

4.40e-0473313914GO:0003013
GeneOntologyBiologicalProcessregulation of tube diameter

HTR2B EDNRA ADORA1 ADORA2A AGTR2 KCNMB4 TACR1

4.47e-042021397GO:0035296
GeneOntologyBiologicalProcessblood vessel diameter maintenance

HTR2B EDNRA ADORA1 ADORA2A AGTR2 KCNMB4 TACR1

4.47e-042021397GO:0097746
GeneOntologyBiologicalProcessblood circulation

SCN11A DRD2 DRD3 HTR2B EDNRA ADORA1 ADORA2A NOX1 SCN3A AGTR2 SCN10A KCNMB4 TACR1

4.48e-0464813913GO:0008015
GeneOntologyBiologicalProcessregulation of tube size

HTR2B EDNRA ADORA1 ADORA2A AGTR2 KCNMB4 TACR1

4.60e-042031397GO:0035150
GeneOntologyBiologicalProcessanterograde trans-synaptic signaling

NPBWR1 DRD2 DRD3 HTR2B SYT9 DGKE GRM4 ZZEF1 CNIH3 OPRK1 EFR3A ADORA1 ADORA2A SCTR KCNMB4 TACR1

5.45e-0493113916GO:0098916
GeneOntologyBiologicalProcesschemical synaptic transmission

NPBWR1 DRD2 DRD3 HTR2B SYT9 DGKE GRM4 ZZEF1 CNIH3 OPRK1 EFR3A ADORA1 ADORA2A SCTR KCNMB4 TACR1

5.45e-0493113916GO:0007268
GeneOntologyBiologicalProcessbehavioral response to cocaine

DRD2 DRD3 OPRK1

5.46e-04241393GO:0048148
GeneOntologyBiologicalProcessgrooming behavior

DRD2 MC4R NMUR2

5.46e-04241393GO:0007625
GeneOntologyBiologicalProcessnervous system process involved in regulation of systemic arterial blood pressure

DRD2 AGTR2 TACR1

5.46e-04241393GO:0001976
GeneOntologyBiologicalProcessdopamine transport

DRD2 DRD3 OPRK1 TGM2

5.91e-04571394GO:0015872
GeneOntologyBiologicalProcesstrans-synaptic signaling

NPBWR1 DRD2 DRD3 HTR2B SYT9 DGKE GRM4 ZZEF1 CNIH3 OPRK1 EFR3A ADORA1 ADORA2A SCTR KCNMB4 TACR1

5.98e-0493913916GO:0099537
GeneOntologyBiologicalProcessadenylate cyclase-activating adrenergic receptor signaling pathway

DRD2 DRD3 GPR101

6.18e-04251393GO:0071880
GeneOntologyBiologicalProcessnegative regulation of secretion by cell

DRD2 DRD3 RHBDF2 FFAR4 OPRK1 ADORA1 AGTR2

6.30e-042141397GO:1903531
GeneOntologyBiologicalProcessnegative regulation of circadian sleep/wake cycle, sleep

DRD2 ADORA1

6.64e-0461392GO:0042321
GeneOntologyBiologicalProcessadenylate cyclase-inhibiting dopamine receptor signaling pathway

DRD2 DRD3

6.64e-0461392GO:0007195
GeneOntologyBiologicalProcessglycerophospholipid biosynthetic process

PIGB HTR2B DGKE EFR3A PIK3R4 MTMR14 PIGO

6.84e-042171397GO:0046474
GeneOntologyBiologicalProcessdetection of temperature stimulus involved in sensory perception of pain

SCN11A ADORA1 SCN10A

6.95e-04261393GO:0050965
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN11A SCN3A SCN10A

1.83e-04171393GO:0001518
GeneOntologyCellularComponentC-fiber

SCN11A SCN10A

2.61e-0441392GO:0044299
MousePhenoabnormal touch/ nociception

SCN11A PRLHR MC1R NMUR2 PHGDH OPRK1 ADORA1 ADORA2A AGTR2 TMEM132A SCN10A TACR1 KCNT1

1.68e-063769613MP:0001968
MousePhenoabnormal behavioral response to addictive substance

PRLHR DRD2 DRD3 OPRK1 ADORA2A TACR1 ALK

6.27e-06102967MP:0009748
MousePhenoimpaired behavioral response to addictive substance

DRD2 DRD3 OPRK1 ADORA2A TACR1

1.35e-0545965MP:0009750
MousePhenoabnormal pain threshold

SCN11A PRLHR MC1R NMUR2 OPRK1 ADORA1 ADORA2A AGTR2 SCN10A TACR1

1.45e-052679610MP:0001970
MousePhenoabnormal behavioral response to alcohol

DRD2 DRD3 ADORA2A ALK

2.00e-0524964MP:0020157
MousePhenoimpaired behavioral response to morphine

DRD3 OPRK1 TACR1

3.64e-0510963MP:0009757
MousePhenoshort mandibular coronoid process

PTCH1 EDNRA

4.67e-052962MP:0030284
MousePhenoabnormal behavioral response to xenobiotic

PRLHR DRD2 DRD3 MC2R OPRK1 SLC7A8 ADORA2A TACR1 KCNT1 ALK

5.06e-053099610MP:0009745
MousePhenoabnormal behavioral response to morphine

DRD3 OPRK1 TACR1

8.54e-0513963MP:0020159
MousePhenoabnormal conditioned place preference behavior

PRLHR DRD2 DRD3 TACR1

9.29e-0535964MP:0009711
MousePhenoabnormal mechanical nociception

SCN11A PRLHR SCN10A KCNT1

1.04e-0436964MP:0002734
MousePhenoincreased circulating adrenocorticotropin level

DRD2 MC2R AGTR2

1.08e-0414963MP:0001748
MousePhenoabnormal drinking behavior

DRD2 DRD3 PHGDH ADORA2A AGTR2 SCTR ALK

1.10e-04159967MP:0001422
MousePhenoimpaired behavioral response to xenobiotic

DRD2 DRD3 OPRK1 ADORA2A TACR1

2.62e-0483965MP:0009747
MousePhenoabnormal tricuspid valve cusp morphology

COL18A1 ADAM17

2.78e-044962MP:0010622
MousePhenoincreased susceptibility to weight gain

NPBWR1 PRLHR DRD3 MC4R NMUR2 FFAR4

2.81e-04131966MP:0005455
MousePhenoabnormal circulating corticosterone level

PRLHR DRD2 MC2R AGTR2 TACR1

3.44e-0488965MP:0005345
MousePhenoabnormal fluid intake

DRD2 DRD3 PHGDH AGTR2 SCTR ALK

3.44e-04136966MP:0011947
DomainGPCR_Rhodpsn_7TM

OR51T1 NPBWR1 NPBWR2 PRLHR DRD2 OXER1 DRD3 HTR2B MLNR MC1R MC2R MC4R MC5R NMUR2 GPR101 OR52N1 EDNRA FFAR4 OPRK1 OR52E2 CXCR5 OR6F1 ADORA1 ADORA2A OR52K1 OR2A12 OR52A5 ACKR3 OR52D1 OR52N2 AGTR2 OR52E4 TACR1 OR51G1 OR52K2 OR52B2 GPR45

2.96e-2267013937IPR017452
Domain7tm_1

OR51T1 NPBWR1 NPBWR2 PRLHR DRD2 OXER1 DRD3 HTR2B MLNR MC1R MC2R MC4R MC5R NMUR2 GPR101 OR52N1 EDNRA FFAR4 OPRK1 OR52E2 CXCR5 OR6F1 ADORA1 ADORA2A OR52K1 OR2A12 OR52A5 ACKR3 OR52D1 OR52N2 AGTR2 OR52E4 TACR1 OR51G1 OR52K2 OR52B2 GPR45

4.23e-2267713937PF00001
DomainG_PROTEIN_RECEP_F1_1

OR51T1 NPBWR1 NPBWR2 PRLHR DRD2 OXER1 DRD3 HTR2B MLNR MC1R MC2R MC4R MC5R NMUR2 GPR101 OR52N1 EDNRA FFAR4 OPRK1 OR52E2 CXCR5 OR6F1 ADORA1 ADORA2A OR52K1 OR2A12 OR52A5 ACKR3 OR52D1 OR52N2 AGTR2 OR52E4 TACR1 OR51G1 OR52K2 OR52B2 GPR45

6.33e-2268513937PS00237
DomainG_PROTEIN_RECEP_F1_2

OR51T1 NPBWR1 NPBWR2 PRLHR DRD2 OXER1 DRD3 HTR2B MLNR MC1R MC2R MC4R MC5R NMUR2 GPR101 OR52N1 EDNRA FFAR4 OPRK1 OR52E2 CXCR5 OR6F1 ADORA1 ADORA2A OR52K1 OR2A12 OR52A5 ACKR3 OR52D1 OR52N2 AGTR2 OR52E4 TACR1 OR51G1 OR52K2 OR52B2 GPR45

8.53e-2269113937PS50262
DomainGPCR_Rhodpsn

OR51T1 NPBWR1 NPBWR2 PRLHR DRD2 OXER1 DRD3 HTR2B MLNR MC1R MC2R MC4R MC5R NMUR2 GPR101 OR52N1 EDNRA FFAR4 OPRK1 OR52E2 CXCR5 OR6F1 ADORA1 ADORA2A OR52K1 OR2A12 OR52A5 ACKR3 OR52D1 OR52N2 AGTR2 OR52E4 TACR1 OR51G1 OR52K2 OR52B2 GPR45

8.97e-2269213937IPR000276
Domain7TM_GPCR_Srsx

NPBWR2 PRLHR DRD2 DRD3 HTR2B MLNR MC1R MC2R MC4R MC5R NMUR2 OPRK1 OR6F1 ADORA1 ADORA2A OR52A5

1.90e-1611213916SM01381
DomainMelcrt_ACTH_rcpt

MC1R MC2R MC4R MC5R

4.36e-0861394IPR001671
DomainOlfact_rcpt

OR51T1 OR52N1 OR52E2 OR6F1 OR52K1 OR2A12 OR52A5 OR52D1 OR52N2 OR52E4 OR51G1 OR52K2 OR52B2

7.72e-0639313913IPR000725
DomainNa_channel_asu

SCN11A SCN3A SCN10A

4.66e-05101393IPR001696
DomainNa_trans_assoc

SCN11A SCN3A SCN10A

4.66e-05101393IPR010526
DomainNa_trans_assoc

SCN11A SCN3A SCN10A

4.66e-05101393PF06512
DomainNeuropept_B/W_rcpt

NPBWR1 NPBWR2

5.50e-0521392IPR009150
DomainMelancort_rcpt

MC4R MC5R

1.64e-0431392IPR001908
DomainAdenosn_rcpt

ADORA1 ADORA2A

3.27e-0441392IPR001634
DomainATII_rcpt

CXCR5 AGTR2

5.42e-0451392IPR000248
DomainDopamine_rcpt

DRD2 DRD3

5.42e-0451392IPR000929
DomainPH-BEACH_dom

WDFY4 WDFY3

1.50e-0381392IPR023362
DomainPeptidase_S54_rhomboid

RHBDD1 RHBDF2

1.50e-0381392IPR002610
Domain-

WDFY4 WDFY3

1.50e-03813922.30.29.40
DomainPH_BEACH

WDFY4 WDFY3

1.50e-0381392PS51783
DomainBEACH_dom

WDFY4 WDFY3

1.91e-0391392IPR000409
DomainRhomboid

RHBDD1 RHBDF2

1.91e-0391392PF01694
DomainPeptidase_S54_rhomboid_dom

RHBDD1 RHBDF2

1.91e-0391392IPR022764
DomainBEACH

WDFY4 WDFY3

1.91e-0391392PS50197
DomainBeach

WDFY4 WDFY3

1.91e-0391392PF02138
Domain-

WDFY4 WDFY3

1.91e-03913921.10.1540.10
Domain-

RHBDD1 RHBDF2

1.91e-03913921.20.1540.10
DomainBeach

WDFY4 WDFY3

1.91e-0391392SM01026
Domainig

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

3.01e-031901396PF00047
DomainImmunoglobulin

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

3.01e-031901396IPR013151
DomainARM-type_fold

INTS1 WDFY4 EFR3A PIK3R4 XPO6 ATXN10 WDFY3 TARBP1

3.91e-033391398IPR016024
DomainARM-like

WDFY4 EFR3A PIK3R4 XPO6 ATXN10 WDFY3 TARBP1

4.13e-032701397IPR011989
DomainFN_type2_col-bd

IGF2R LY75

4.72e-03141392IPR000562
DomainFN2_2

IGF2R LY75

4.72e-03141392PS51092
DomainDynein_HC_stalk

DNHD1 DNAH2

4.72e-03141392IPR024743
DomainDynein_heavy_dom-2

DNHD1 DNAH2

4.72e-03141392IPR013602
DomainTUDOR

TDRD15 TDRD12

4.72e-03141392PF00567
DomainDHC_N2

DNHD1 DNAH2

4.72e-03141392PF08393
DomainMT

DNHD1 DNAH2

4.72e-03141392PF12777
Domainfn2

IGF2R LY75

4.72e-03141392PF00040
DomainFN2_1

IGF2R LY75

4.72e-03141392PS00023
DomainFN2

IGF2R LY75

4.72e-03141392SM00059
DomainDHC_fam

DNHD1 DNAH2

5.42e-03151392IPR026983
DomainDynein_heavy_dom

DNHD1 DNAH2

5.42e-03151392IPR004273
DomainDynein_heavy

DNHD1 DNAH2

5.42e-03151392PF03028
Domain-

WDFY4 EFR3A PIK3R4 XPO6 ATXN10 WDFY3

6.39e-0322213961.25.10.10
PathwayWP_GPCRS_NONODORANT

NPBWR1 PRLHR DRD2 DRD3 HTR2B MC1R MC2R MC4R MC5R NMUR2 GRM4 EDNRA FFAR4 OPRK1 CXCR5 ADORA1 ADORA2A ACKR3 AGTR2 SCTR ADGRE5 TACR1

1.55e-1626611322MM15843
PathwayREACTOME_GPCR_LIGAND_BINDING

NPBWR1 NPBWR2 PRLHR DRD2 OXER1 DRD3 HTR2B MLNR MC1R MC2R MC4R MC5R NMUR2 PTCH1 GRM4 EDNRA FFAR4 OPRK1 CXCR5 ADORA1 ADORA2A ACKR3 AGTR2 SCTR ADGRE5 TACR1 TAS2R60

2.58e-1646311327M507
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

NPBWR1 NPBWR2 PRLHR DRD2 OXER1 DRD3 HTR2B MLNR MC1R MC2R MC4R MC5R NMUR2 EDNRA FFAR4 OPRK1 CXCR5 ADORA1 ADORA2A ACKR3 AGTR2 TACR1

1.42e-1433011322M18334
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

NPBWR1 NPBWR2 PRLHR DRD2 DRD3 HTR2B MLNR MC1R MC2R MC4R MC5R NMUR2 EDNRA OPRK1 CXCR5 ADORA1 ADORA2A ACKR3 AGTR2 GPR45

1.72e-1426011320M39397
PathwayREACTOME_SIGNALING_BY_GPCR

NPBWR1 NPBWR2 PRLHR DRD2 OXER1 DRD3 HTR2B MLNR RGS22 MC1R MC2R MC4R MC5R DGKE NMUR2 PTCH1 GRM4 EDNRA FFAR4 OPRK1 CXCR5 ADORA1 ADORA2A ACKR3 AGTR2 SCTR ADGRE5 TACR1 TAS2R60 GPR45

1.90e-1470211330M746
PathwayKEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION

NPBWR1 NPBWR2 PRLHR DRD2 DRD3 HTR2B MLNR MC1R MC2R MC4R MC5R NMUR2 GRM4 EDNRA OPRK1 ADORA1 ADORA2A AGTR2 SCTR TACR1

4.05e-1427211320M13380
PathwayREACTOME_GPCR_LIGAND_BINDING

NPBWR1 PRLHR DRD2 DRD3 HTR2B MC1R MC2R MC4R MC5R NMUR2 GRM4 EDNRA OPRK1 CXCR5 ADORA1 ADORA2A ACKR3 AGTR2 SCTR ADGRE5 TACR1 TAS2R60

3.02e-1243011322MM15160
PathwayREACTOME_SIGNALING_BY_GPCR

NPBWR1 PRLHR DRD2 DRD3 HTR2B MC1R MC2R MC4R MC5R DGKE NMUR2 GRM4 EDNRA FFAR4 OPRK1 CXCR5 ADORA1 ADORA2A ACKR3 AGTR2 SCTR ADGRE5 TACR1 TAS2R60 GPR45

3.68e-1164611325MM14962
PathwayREACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS

NPBWR1 NPBWR2 PRLHR MLNR MC1R MC2R MC4R MC5R NMUR2 EDNRA OPRK1 CXCR5 ACKR3 AGTR2 TACR1

4.83e-1119711315M12289
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

NPBWR1 PRLHR DRD2 DRD3 HTR2B MC1R MC2R MC4R MC5R NMUR2 EDNRA OPRK1 CXCR5 ADORA1 ADORA2A ACKR3 AGTR2 TACR1

1.46e-1033311318MM14963
PathwayWP_GPCRS_PEPTIDE

MC1R MC2R MC4R MC5R EDNRA OPRK1 CXCR5 AGTR2 TACR1

4.28e-09701139MM15959
PathwayREACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS

NPBWR1 PRLHR MC1R MC2R MC4R MC5R NMUR2 EDNRA OPRK1 CXCR5 ACKR3 AGTR2 TACR1

5.89e-0919711313MM14970
PathwayWP_PEPTIDE_GPCRS

MC1R MC2R MC4R MC5R EDNRA OPRK1 CXCR5 AGTR2 TACR1

7.99e-09751139M39696
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

DRD3 HTR2B MC1R MC2R MC4R MC5R OPRK1 CXCR5 ADORA2A ACKR3 AGTR2 GPR45

3.02e-0818611312MM15994
PathwayREACTOME_G_ALPHA_I_SIGNALLING_EVENTS

NPBWR1 NPBWR2 OXER1 DRD3 RGS22 NMUR2 GRM4 OPRK1 CXCR5 ADORA1 ACKR3 AGTR2 TAS2R60

1.35e-0631411313M600
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR51T1 OR52N1 OR52E2 OR6F1 OR52K1 OR2A12 OR52A5 OR52D1 OR52N2 OR52E4 OR51G1 OR52K2 OR52B2

1.39e-0538911313M14091
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR51T1 OR52N1 OR52E2 OR6F1 OR52K1 OR2A12 OR52A5 OR52D1 OR52N2 OR52E4 OR51G1 OR52K2 OR52B2

2.89e-0541711313M4072
PathwayREACTOME_DAP12_INTERACTIONS

KIR2DS2 KIR2DS1 KIR2DS4 KIR2DS5 KIR3DS1

3.19e-05461135M27151
PathwayREACTOME_ALK_MUTANTS_BIND_TKIS

EML4 BIRC6 ALK

1.05e-04121133M42522
PathwayREACTOME_G_ALPHA_I_SIGNALLING_EVENTS

NPBWR1 DRD3 NMUR2 GRM4 OPRK1 CXCR5 ADORA1 ACKR3 AGTR2 TAS2R60

1.08e-0428911310MM15057
PathwayWP_GPCRS_OTHER

DRD2 MC4R EDNRA OPRK1 ADORA1 ADGRE5

1.20e-04961136MM15939
PathwayREACTOME_G_ALPHA_S_SIGNALLING_EVENTS

MC1R MC2R MC4R MC5R ADORA2A SCTR GPR45

1.50e-041431137MM15055
PathwayREACTOME_SENSORY_PERCEPTION

OR51T1 GRM4 OR52N1 OR52E2 OR6F1 OR52K1 OR2A12 OR52A5 OR52D1 OR52N2 SCN3A OR52E4 OR51G1 OR52K2 OR52B2

1.65e-0463611315M41834
PathwayWP_ADHD_AND_AUTISM_ASD_PATHWAYS

AANAT SCN11A DRD2 HTR2B MC4R GRM4 PIK3R4 ADORA2A NOX1 SCN3A SCN10A

1.74e-0436711311M48346
PathwayWP_SLEEP_REGULATION

DRD2 DRD3 ADORA1 ADORA2A

2.34e-04381134M39504
PathwayREACTOME_G_ALPHA_S_SIGNALLING_EVENTS

MC1R MC2R MC4R MC5R ADORA2A SCTR GPR45

2.68e-041571137M4904
PathwayREACTOME_DOPAMINE_RECEPTORS

DRD2 DRD3

6.27e-0451132M27301
PathwayKEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_JAK_STAT_SIGNALING_PATHWAY

JAK3 ALK

6.27e-0451132M48987
PathwayREACTOME_DOPAMINE_RECEPTORS

DRD2 DRD3

6.27e-0451132MM15007
PathwayREACTOME_G_ALPHA_Q_SIGNALLING_EVENTS

HTR2B MLNR DGKE NMUR2 EDNRA FFAR4 TACR1

1.81e-032171137M18437
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SCN11A SCN3A SCN10A

1.91e-03311133M877
PathwayWP_MONOAMINE_GPCRS

DRD2 DRD3 HTR2B

1.91e-03311133MM15871
Pubmed

In contrast to other stimulatory natural killer cell immunoglobulin-like receptor loci, several KIR2DS5 alleles predominate in African Americans.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5

1.02e-125141519410616
Pubmed

[Genotype analysis of killer cell immunoglobulin-like receptors in Graves' disease patients].

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

1.81e-1211141619664392
Pubmed

Association of killer cell immunoglobulin-like receptor 2DL5 with systemic lupus erythematosus and accompanying infections.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

3.61e-1212141620371502
Pubmed

Distribution of killer cell immunoglobulin-like receptors (KIR) and their HLA-C ligands in two Iranian populations.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

3.61e-1212141619936734
Pubmed

Association of killer cell immunoglobulin-like receptors with primary Sjogren's syndrome.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

3.61e-1212141619181658
Pubmed

[Relationship between CMV reactivation and KIR haplotype/HLA-Cw genotype in patients after unrelated-donor hematopoietic stem cell transplantation.].

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

3.61e-1212141620137308
Pubmed

KIR and HLA genotypes are associated with disease progression and survival following autologous hematopoietic stem cell transplantation for high-risk neuroblastoma.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

6.69e-1213141619934297
Pubmed

Different KIRs confer susceptibility and protection to adults with latent autoimmune diabetes in Latvian and Asian Indian populations.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

6.69e-1213141619120281
Pubmed

[Study on the polymorphism of killer cell immunoglobulin like receptor (KIR) gene with systemic lupus erythematosus of North population in China].

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

6.69e-1213141618687225
Pubmed

Dissociation of heterotrimeric g proteins in cells.

NPBWR1 NPBWR2 DRD2 OXER1 DRD3 NMUR2 EDNRA OPRK1 CXCR5 ADORA1 ACKR3 AGTR2

1.07e-111791411218577758
Pubmed

Frequencies of killer immunoglobulin-like receptor genotypes influence susceptibility to spontaneous abortion.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

1.17e-1114141619875891
Pubmed

Multiple sclerosis associates with LILRA3 deletion in Spanish patients.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

1.17e-1114141619421224
Pubmed

Distribution of killer cell immunoglobulin-like receptor genes in the Chinese Han population.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

1.17e-1114141615896204
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in a Caucasian population of southern Brazil.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

1.94e-1115141620082646
Pubmed

Killer cell immunoglobulin-like receptors in HLA-B27-associated acute anterior uveitis, with and without axial spondyloarthropathy.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

1.94e-1115141619850842
Pubmed

[Killer cell immunoglobin-like receptor and its ligand gene polymorphisms in Hunan Han patients with type 1 diabetes].

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

1.94e-1115141620356536
Pubmed

Disparate distribution of activating and inhibitory killer cell immunoglobulin-like receptor genes in patients with systemic lupus erythematosus.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

1.94e-1115141619926642
Pubmed

Natural killer-cell receptor polymorphisms and posttransplantation non-Hodgkin lymphoma.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

1.94e-1115141620207982
Pubmed

Killer immunoglobulin-like receptors (KIR2DL2 and/or KIR2DS2) in presence of their ligand (HLA-C1 group) protect against chronic myeloid leukaemia.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

1.94e-1115141619493232
Pubmed

Inhibitory KIR and specific HLA-C gene combinations confer susceptibility to or protection against chronic hepatitis B.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

1.94e-1115141620643584
Pubmed

Killer cell immunoglobulin-like receptor genotype and killer cell immunoglobulin-like receptor-human leukocyte antigen C ligand compatibility affect the severity of hepatitis C virus recurrence after liver transplantation.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

1.94e-1115141619326408
Pubmed

Killer cell immunoglobulin-like receptor gene-cluster 3DS1-2DL5-2DS1-2DS5 predisposes susceptibility to Vogt-Koyanagi-Harada syndrome in Japanese individuals.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

3.09e-1116141619897003
Pubmed

Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Java, Kalimantan, Timor and Irian Jaya.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

3.09e-1116141619000141
Pubmed

Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Sumatra, Sulawesi and Moluccas Islands.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

3.09e-1116141620670355
Pubmed

Asian population frequencies and haplotype distribution of killer cell immunoglobulin-like receptor (KIR) genes among Chinese, Malay, and Indian in Singapore.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

3.09e-1116141618668235
Pubmed

Distribution of killer cell immunoglobulin-like receptor (KIR) genotypes in patients with familial Mediterranean fever.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

3.09e-1116141619309280
Pubmed

Activating killer cell immunoglobulin-like receptor genes' association with recurrent miscarriage.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

3.09e-1116141619527230
Pubmed

Polymorphisms of KIR gene and HLA-C alleles: possible association with susceptibility to HLA-B27-positive patients with ankylosing spondylitis.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

3.09e-1116141620652381
Pubmed

Influence of activating and inhibitory killer immunoglobulin-like receptors on predisposition to recurrent miscarriages.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

3.09e-1116141619279038
Pubmed

No association of KIR genes with Behcet's disease.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

3.09e-1116141617868255
Pubmed

A study of the killer cell immunoglobulin-like receptor gene KIR2DS1 in a Caucasoid Brazilian population with psoriasis vulgaris.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

3.09e-1116141618643961
Pubmed

Report from the killer immunoglobulin-like receptor (KIR) anthropology component of the 15th International Histocompatibility Workshop: worldwide variation in the KIR loci and further evidence for the co-evolution of KIR and HLA.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

3.09e-1116141620331834
Pubmed

HLA-DQA1*0505 sharing and killer immunoglobulin-like receptors in sub fertile couples: report from the 15th International Histocompatibility Workshop.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

3.09e-1116141620210919
Pubmed

[Effects of killer immunoglobulin-like receptor and human leukocyte antigen class I ligand on the prognosis of related donor hematopoietic stem cell transplantation].

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

4.76e-1117141619968064
Pubmed

Association of KIR2DS1 and KIR2DS3 with fatal outcome in Ebola virus infection.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

4.76e-1117141620878400
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in the Tibetan ethnic minority group of China.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

4.76e-1117141620650299
Pubmed

The beneficial impact of missing KIR ligands and absence of donor KIR2DS3 gene on outcome following unrelated hematopoietic SCT for myeloid leukemia in the Chinese population.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

4.76e-1117141620173784
Pubmed

The role of killer immunoglobulin-like receptor haplotypes on the outcome of unrelated donor haematopoietic SCT for thalassaemia.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

4.76e-1117141620173792
Pubmed

Role of killer cell immunoglobulin-like receptor gene content and human leukocyte antigen-C group in susceptibility to human T-lymphotropic virus 1-associated myelopathy/tropical spastic paraparesis in Peru.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

4.76e-1117141620483367
Pubmed

[Analysis of natural killer cell immunoglobulin-like receptor genes in Chinese].

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

4.76e-1117141619218127
Pubmed

KIR genes and KIR ligands affect occurrence of acute GVHD after unrelated, 12/12 HLA matched, hematopoietic stem cell transplantation.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

4.76e-1117141619169284
Pubmed

Killer cell immunoglobulin-like receptor gene polymorphisms in patients with leukemia: possible association with susceptibility to the disease.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

4.76e-1117141619450876
Pubmed

Distribution of killer-cell immunoglobulin-like receptor genes in Eastern mainland Chinese Han and Taiwanese Han populations.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

4.76e-1117141619761533
Pubmed

NullHap--a versatile application to estimate haplotype frequencies from unphased genotypes in the presence of null alleles.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5

5.66e-118141518681957
Pubmed

Killer immunoglobulin-like receptor ligand HLA-Bw4 protects against multiple sclerosis.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

7.11e-1118141619630074
Pubmed

Combination of KIR 2DL2 and HLA-C1 (Asn 80) confers susceptibility to type 1 diabetes in Latvians.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

7.11e-1118141619046302
Pubmed

Association of killer cell immunoglobulin-like receptors and human leukocyte antigen-C genotypes in South Brazilian with type 1 diabetes.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

7.11e-1118141620580654
Pubmed

Influence of HLA class I and HLA-KIR compound genotypes on HIV-2 infection and markers of disease progression in a Manjako community in West Africa.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

7.11e-1118141620519398
Pubmed

Effect of killer immunoglobulin-like receptors in the response to combined treatment in patients with chronic hepatitis C virus infection.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

7.11e-1118141619846535
Pubmed

KIR and HLA gene combinations in Vogt-Koyanagi-Harada disease.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

1.04e-1019141618571006
Pubmed

Association between killer-cell immunoglobulin-like receptor genotypes and leprosy in Brazil.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

1.04e-1019141618778326
Pubmed

Associations between genes for killer immunoglobulin-like receptors and their ligands in patients with solid tumors.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

1.04e-1019141620600442
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in a Southern Brazilian population from the state of Paraná.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

1.04e-1019141618848853
Pubmed

Alternatively spliced forms of human killer inhibitory receptors.

KIR2DS2 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

1.27e-10914158662091
Pubmed

Combination of KIR and HLA gene variants augments the risk of developing birdshot chorioretinopathy in HLA-A*29-positive individuals.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR3DS1

1.27e-109141518340360
Pubmed

Compound KIR-HLA genotype analyses in the Iranian population by a novel PCR-SSP assay.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

1.48e-1020141620193031
Pubmed

HLA and KIR frequencies in Sicilian Centenarians.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

1.48e-1020141620426625
Pubmed

Activating killer cell immunoglobulin-like receptors 3DS1 and 2DS1 protect against developing the severe form of recurrent respiratory papillomatosis.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

2.06e-1021141619861144
Pubmed

Different patterns of evolution in the centromeric and telomeric regions of group A and B haplotypes of the human killer cell Ig-like receptor locus.

KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

2.53e-1010141521206914
Pubmed

Distribution of KIR genes in the population of unrelated individuals homozygous for ancestral haplotype AH8.1 (HLA-A1B8DR3).

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

2.82e-1022141620492596
Pubmed

Natural killer cells and immune surveillance.

KIR2DS2 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

4.62e-1011141518830515
Pubmed

Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors.

NPBWR1 NPBWR2 DRD2 DRD3 HTR2B OPRK1 ADORA1 ADORA2A ACKR3 AGTR2 SCTR

6.62e-102001411118240029
Pubmed

Adrenocorticotropic hormone directly stimulates testosterone production by the fetal and neonatal mouse testis.

MC1R MC2R MC4R MC5R

1.29e-095141412865302
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR51T1 OR52E2 OR6F1 OR52K1 OR2A12 OR52A5 OR52D1 OR52N2 OR5H8 OR52E4 OR51G1 OR52K2 OR52B2

1.52e-093401411311875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR51T1 OR52E2 OR6F1 OR52K1 OR2A12 OR52A5 OR52D1 OR52N2 OR5H8 OR52E4 OR51G1 OR52K2 OR52B2

1.52e-093401411311802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR51T1 OR52E2 OR6F1 OR52K1 OR2A12 OR52A5 OR52D1 OR52N2 OR5H8 OR52E4 OR51G1 OR52K2 OR52B2

1.69e-093431411332295537
Pubmed

Immunogenetic characteristics of patients with autoimmune gastritis.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

1.75e-0929141620082482
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR51T1 OR52E2 OR6F1 OR52K1 OR2A12 OR52A5 OR52D1 OR52N2 OR5H8 OR52E4 OR51G1 OR52K2 OR52B2

1.88e-093461411314611657
Pubmed

[Genotype and haplotype analysis of killer cell immunoglobulin-like receptors in ankylosing spondylitis].

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR3DS1

1.98e-0914141519489269
Pubmed

Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia.

KIR2DS2 KIR2DS1 KIR2DS4 KIR2DS5 KIR3DS1

1.98e-0914141518945962
Pubmed

KIR genes polymorphism in Argentinean Caucasoid and Amerindian populations.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5

2.96e-0915141517498266
Pubmed

Killer cell immunoglobulin-like receptor gene polymorphism in lymphoproliferative diseases of granular lymphocytes in a Japanese population.

KIR2DS2 KIR2DS1 KIR2DS3 KIR3DS1

3.86e-096141420528243
Pubmed

Associations of killer cell immunoglobulin-like receptor genes with complications of rheumatoid arthritis.

KIR2DS2 KIR2DS1 KIR2DS3 KIR3DS1

3.86e-096141417882223
Pubmed

[Polymorphism of killer cell immunoglobulin-like receptors gene family in Zhejiang Han population].

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5

4.30e-0916141516403292
Pubmed

Role of human leukocyte antigen, killer-cell immunoglobulin-like receptors, and cytokine gene polymorphisms in leptospirosis.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

5.88e-0935141619683555
Pubmed

Natural killer cell receptor repertoire and their ligands, and the risk of CMV infection after kidney transplantation.

KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

6.07e-0917141519032228
Pubmed

Signatures of natural selection and coevolution between killer cell immunoglobulin-like receptors (KIR) and HLA class I genes.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5

8.37e-0918141520200544
Pubmed

Distribution of killer cell immunoglobulin-like receptor genes in the mestizo population from Venezuela.

KIR2DS2 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

8.37e-0918141520210918
Pubmed

MRAP and MRAP2 are bidirectional regulators of the melanocortin receptor family.

MC1R MC2R MC4R MC5R

8.97e-097141419329486
Pubmed

The structure and evolution of the melanocortin and MCH receptors in fish and mammals.

MC1R MC2R MC4R MC5R

8.97e-097141412620396
Pubmed

Effects of recombinant agouti-signaling protein on melanocortin action.

MC1R MC2R MC4R MC5R

8.97e-09714149058374
Pubmed

Agouti/melanocortin interactions with leptin pathways in obesity.

MC1R MC2R MC4R MC5R

1.79e-08814149763877
Pubmed

Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains.

KIR2DS2 KIR2DS3 KIR2DS4 KIR2DS5

3.21e-08914147749980
Pubmed

Polymorphisms of killer cell immunoglobulin-like receptor gene: possible association with susceptibility to or clearance of hepatitis B virus infection in Chinese Han population.

KIR2DS2 KIR2DS1 KIR2DS3 KIR3DS1

3.21e-089141418074414
Pubmed

The human olfactory receptor gene family.

OR51T1 OR52N1 OR52E2 OR6F1 OR52K1 OR2A12 OR52A5 OR52D1 OR52N2 OR5H8 OR52E4 OR51G1 OR52K2 OR52B2

4.89e-085411411414983052
Pubmed

Assessment of killer cell immunoglobulinlike receptor expression and corresponding HLA class I phenotypes demonstrates heterogenous KIR expression independent of anticipated HLA class I ligands.

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS5

5.33e-0810141412559621
Pubmed

Melanocortins contribute to sequential differentiation and enucleation of human erythroblasts via melanocortin receptors 1, 2 and 5.

MC1R MC2R MC5R

6.52e-083141325860801
Pubmed

A novel surface molecule homologous to the p58/p50 family of receptors is selectively expressed on a subset of human natural killer cells and induces both triggering of cell functions and proliferation.

KIR2DS3 KIR2DS4 KIR2DS5

6.52e-08314138765026
Pubmed

Activating killer immunoglobulin-like receptor incompatibilities enhance graft-versus-host disease and affect survival after allogeneic hematopoietic stem cell transplantation.

KIR2DS1 KIR2DS3 KIR2DS5

6.52e-083141319500138
Pubmed

Association of killer cell immunoglobulin-like receptors with pulmonary tuberculosis in Chinese Han.

KIR2DS1 KIR2DS3 KIR3DS1

6.52e-083141322653583
Pubmed

NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRs.

KIR2DS2 KIR2DS4 KIR3DS1

6.52e-083141323325834
Pubmed

KIR2DS1, 2DS5, 3DS1 and KIR2DL5 are associated with the risk of head and neck squamous cell carcinoma in Iranians.

KIR2DS1 KIR2DS5 KIR3DS1

6.52e-083141329408295
Pubmed

[Polymorphism of killer cell immunoglobulin-like receptor gene and its correlation with leukemia].

KIR2DS2 KIR2DS4 KIR2DS5 KIR3DS1

1.25e-0712141417490516
Pubmed

Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse.

OR52K1 OR52A5 OR51G1 OR52K2 OR52B2

2.21e-0733141517350283
Pubmed

Killer immunoglobulin-like receptor gene repertoire influences viral load of primary human cytomegalovirus infection in renal transplant patients.

KIR2DS1 KIR2DS5 KIR3DS1

2.60e-074141325253288
Pubmed

Genetic interdependence of adenosine and dopamine receptors: evidence from receptor knockout mice.

DRD2 DRD3 ADORA2A

2.60e-074141316476524
Pubmed

Adenosine A1 and A2A receptors are not upstream of caffeine's dopamine D2 receptor-dependent aversive effects and dopamine-independent rewarding effects.

DRD2 ADORA1 ADORA2A

2.60e-074141320576036
Pubmed

Exercise-Induced Adaptations to the Mouse Striatal Adenosine System.

DRD2 ADORA1 ADORA2A

2.60e-074141332399024
Pubmed

Chromosomal mapping of A1 and A2 adenosine receptors, VIP receptor, and a new subtype of serotonin receptor.

ADORA1 ADORA2A ACKR3

2.60e-07414131662665
Pubmed

Proteochemometric mapping of the interaction of organic compounds with melanocortin receptor subtypes.

MC1R MC4R MC5R

2.60e-074141315470082
InteractionASIP interactions

MC1R MC2R MC4R MC5R

2.58e-06161274int:ASIP
InteractionKIR2DS2 interactions

INTS1 KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS5

3.41e-06371275int:KIR2DS2
Cytoband11p15.4

DNHD1 OR51T1 SYT9 OR52N1 OR52E2 OR52K1 OR52A5 OR52D1 OR52N2 OR52E4 OR51G1 OR52K2 OR52B2

6.66e-142001411311p15.4
CytobandEnsembl 112 genes in cytogenetic band chr11p15

DNHD1 OR51T1 ANO9 SYT9 OR52N1 OR52E2 OR52K1 GTF2H1 OR52A5 OR52D1 OR52N2 OR52E4 OR51G1 OR52K2 OR52B2

2.70e-1056414115chr11p15
Cytoband19q13.4

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

1.74e-0779141619q13.4
Cytoband18p11.2

MC2R MC5R

3.32e-049141218p11.2
Cytoband2q24

SCN3A LY75

5.06e-041114122q24
Cytoband8q24.22

EFR3A OC90

1.24e-031714128q24.22
GeneFamilyOlfactory receptors, family 52

OR52N1 OR52E2 OR52K1 OR52A5 OR52D1 OR52N2 OR52E4 OR52K2 OR52B2

1.37e-11491109165
GeneFamilyCD molecules|Killer cell immunoglobulin like receptors

KIR2DS2 KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DS1

7.73e-10181106620
GeneFamilyMelanocortin receptors

MC1R MC2R MC4R MC5R

6.46e-0951104236
GeneFamilyADAM metallopeptidase domain containing|CD molecules

KIR2DS2 IL18R1 CLEC12A CXCR5 IGF2R CD226 ADGRE5 ADAM17 KIR2DS1 LY75 KIR2DS4 KIR2DS5 ALK

8.05e-0739411013471
GeneFamilySodium voltage-gated channel alpha subunits

SCN11A SCN3A SCN10A

1.79e-05911031203
GeneFamilyAdenosine receptors

ADORA1 ADORA2A

2.18e-0441102211
GeneFamilyDopamine receptors

DRD2 DRD3

3.62e-0451102181
GeneFamilyPeptide receptors

PRLHR MLNR

7.55e-0471102220
GeneFamilyWD repeat domain containing|BEACH domain containing

WDFY4 WDFY3

1.28e-03911021230
GeneFamilyNeuropeptide receptors

NPBWR1 NPBWR2

1.60e-03101102854
GeneFamilyRhomboid family

RHBDD1 RHBDF2

3.18e-03141102926
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2-Th.Nr4a2_(Neuron.Gad1Gad2-Th.Nr4a2)--|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

DNHD1 NPBWR1 PRTN3 SLC26A8 NOX1 CD226

4.47e-07941366c73e99890431750b74f984de5c82e33533ab708b
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2-Th.Nr4a2_(Neuron.Gad1Gad2-Th.Nr4a2)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

DNHD1 NPBWR1 PRTN3 SLC26A8 NOX1 CD226

4.47e-079413661bda61101f45f5c4a68453087b880fdc6d9acfca
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2-Th.Nr4a2_(Neuron.Gad1Gad2-Th.Nr4a2)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

DNHD1 NPBWR1 PRTN3 SLC26A8 NOX1 CD226

4.47e-079413669664f74bc0168c92fb8a68cad628323c476f6103
ToppCellCOVID-19-T_cells-CD4+_T_cells|COVID-19 / group, cell type (main and fine annotations)

LRRC8C EML4 IL18R1 PCNX2 JAK3 CD226 ABCD2

2.05e-0619113670646cca78e24aeb6baa9934d3c439b797c567997
ToppCellnucseq-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-CD4_T|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LRRC8C EML4 JAK3 CD226 XPO6 MAP4K1 ADGRE5

2.19e-0619313679c9434a3297b85774b4f0ecab6294f44d738e29f
ToppCelldroplet-Thymus-nan-3m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FFAR4 SLC7A8 SCN3A TMEM132A WDFY3 KCNT1

1.44e-05171136625493a4a7b636920e2cfd984542cc500709c9dcf
ToppCelldroplet-Thymus-nan-3m-Myeloid-professional_antigen_presenting_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FFAR4 SLC7A8 SCN3A TMEM132A WDFY3 KCNT1

1.44e-051711366508b41e3ad2638f9dd546d251b13ff60fc8c3207
ToppCelldroplet-Thymus-nan-3m-Myeloid-Macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FFAR4 SLC7A8 SCN3A TMEM132A WDFY3 KCNT1

1.54e-05173136663f03abca84ae021ff34ff34537838aa8a1ccd11
ToppCellCOVID-19-Heart-VSMC|COVID-19 / Disease (COVID-19 only), tissue and cell type

EDNRA COL18A1 FRY ACKR3 SCN3A KCNT1

1.64e-0517513661125f0d3a5b2388fa77a820dea0288e824d84a82
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS6 IL18R1 MFSD12 FFAR4 OPRK1 QSOX1

1.64e-0517513660992de1c7bffcb6890584357a7a0a8955927da6c
ToppCellfacs-Trachea-24m-Hematologic-lymphocytic-B_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

WDFY4 PHGDH CXCR5 JAK3 ADORA2A MAP4K1

1.70e-051761366318dc722b95e269002fb01a0feb91c0c8539e150
ToppCellfacs-Trachea-24m-Hematologic-lymphocytic-B_cell-B_cell_of_the_trachea|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

WDFY4 PHGDH CXCR5 JAK3 ADORA2A MAP4K1

1.70e-051761366f6891006d816309edabe75b2abf60675f2958e55
ToppCellfacs-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

WDFY4 CLEC12A TBC1D9 FFAR4 MAP4K1 LY75

1.87e-05179136655fde77dae7f9e7f3431c3185d14212a25af83df
ToppCellAdult-Immune-natural_killer_cell-D231|Adult / Lineage, Cell type, age group and donor

APOBEC3G DENND1C PTCH1 JAK3 MLC1 ADGRE5

2.05e-051821366dbf47bf4754d8ec3bc3ab1d5be7a6c47a7afbf43
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

WDFY4 CLEC12A FFAR4 ADGRE5 ADAM17 ALK

2.46e-051881366d7a9fb5b021e127b8d927658a55a71098d513b5c
ToppCellSevere-Lymphoid-NK-Treg|Severe / Condition, Lineage, Cell class and cell subclass

PIGB EOGT MYO18A IL18R1 TRMT44 TYW5

2.61e-051901366e67803bf55a3f8e47a69ff1829c9100f870d7527
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-C|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ANO9 IL18R1 CXCR5 ADORA2A MAP4K1 SLC23A3

2.69e-05191136695ae42d145adb478d886a2259baacc713cd6587b
ToppCellCOVID-19-lung-CD4+_Treg|COVID-19 / Disease (COVID-19 only), tissue and cell type

EML4 PCNX2 JAK3 CD226 MAP4K1 ABCD2

2.69e-0519113665a4ad5ae5c2dbfb225158cb598ef649c26a48350
ToppCellAdult-Immune-natural_killer_cell|Adult / Lineage, Cell type, age group and donor

APOBEC3G DENND1C JAK3 MLC1 CD226 ADGRE5

2.69e-051911366758ec27e47d7662a5175305e98a1506c6859dbf7
ToppCellCOVID-19-lung-CD4+_Treg|lung / Disease (COVID-19 only), tissue and cell type

EML4 PCNX2 JAK3 CD226 MAP4K1 ABCD2

2.69e-05191136673ea3078c1f55cd47e4d99e77b3ce4ff17549d49
ToppCellControl-Lymphoid-T|World / Disease state, Lineage and Cell class

LRRC8C EML4 JAK3 CD226 XPO6 MAP4K1

2.77e-051921366253cf4d2cf88ad8c45b73779336180840bef054b
ToppCellCOVID-19-lung-CD4+_T_cells_metabolically_active|lung / Disease (COVID-19 only), tissue and cell type

DENND1C PCNX2 JAK3 CD226 MAP4K1 ABCD2

2.94e-0519413662a144a1c2d537c8a59aa419206ddd96c23f0aeab
ToppCellnucseq-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LRRC8C APOBEC3G CD226 XPO6 MAP4K1 ADGRE5

3.02e-051951366ffb40486f8097b2c08e8f3b3685d0b8cb8d1bc66
ToppCellnucseq-Immune-Lymphocytic_T/NK|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LRRC8C APOBEC3G CD226 XPO6 MAP4K1 ADGRE5

3.02e-051951366b8124e8a23e6d37b40023608674e67285c6ffe84
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ANO9 RNF213 DGKE PTCH1 CD226 SLC23A3

3.20e-051971366e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EDNRA COL18A1 FRY ACKR3 SCN3A KCNT1

3.29e-0519813667dd874b09c81cc512ccc1e9b65f290a5f94d736e
ToppCellBronchial-10x5prime-Immune_Lymphocytic-T-T_CD8-gdT|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TDRD15 ANO9 APOBEC3G ADORA2A CD226 MAP4K1

3.29e-0519813669dc91a1101eef649a301f0147ecd5c028a9c2b12
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DENND1C IL18R1 JAK3 CD226 MAP4K1 ADGRE5

3.39e-051991366bc93e5c36ab60b66fb633c954b05d4dc09a7f152
ToppCellCOVID_non-vent-Lymphocytic-ILC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

RNF213 PTCH1 IL18R1 IGF2R MLC1 CD226

3.39e-051991366df4f7d5be099e3e6054f3b812ccf70251664e4c0
ToppCellTracheal-NucSeq-Immune_Lymphocytic-NK-ILC|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TDRD15 RHBDF2 APOBEC3G IL18R1 CD226 ADGRE5

3.39e-051991366713fab2e946b300d21215aff1553785e8857ce65
ToppCellCOVID_non-vent-Lymphocytic-ILC-NK_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

RNF213 PTCH1 IL18R1 IGF2R MLC1 CD226

3.39e-051991366ed35d747f11f6ea6a5cb7061057f0a98d9e0db99
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_TRM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DENND1C JAK3 CD226 MAP4K1 ADGRE5 ABCD2

3.39e-051991366b947ecaf912d97869f6df32736b8c2b2dd695d66
ToppCellTracheal-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TDRD15 RHBDF2 APOBEC3G IL18R1 CD226 ADGRE5

3.39e-051991366ffd5b4d58d81b76e01d87016209f16879d81c592
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T-T_CD4|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DENND1C IL18R1 JAK3 CD226 MAP4K1 ADGRE5

3.48e-052001366d8459e45a8396a9ee063666a1928c649162c5727
ToppCellLPS-IL1RA+antiTNF-Myeloid-Dendritic_cells-mDC|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

WDFY4 CLEC12A FFAR4 CD226 MAP4K1

5.33e-051321365f8e2ba53063007d7507f1837ad669b0e4333cd23
ToppCellmetastatic_Brain-T/NK_cells-CD8_low_T|T/NK_cells / Location, Cell class and cell subclass

TDRD15 OXER1 APOBEC3G STT3B SCTR

6.58e-051381365b2ab273f3e62f169b3b9cb82342e6617af99f582
ToppCellPosterior_cortex-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Sc17a7.Oprk1_(Claustrum?)--|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NPBWR1 SCN11A DRD2 OPRK1

7.80e-057413640feb6bd4c4277f62a4f596370c00ed64e79a389b
ToppCellPosterior_cortex-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Sc17a7.Oprk1_(Claustrum?)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NPBWR1 SCN11A DRD2 OPRK1

7.80e-057413644908cbf8ef5881a01a58c26076bd263f8a5665c2
ToppCellPosterior_cortex-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Sc17a7.Oprk1_(Claustrum?)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NPBWR1 SCN11A DRD2 OPRK1

7.80e-05741364c26fdce3f979a2f5280a6adcc980419389aec3cb
ToppCellLPS-antiTNF-Stromal_mesenchymal-Fibroblasts-Monocytes-Macrophages|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

INTS1 PTCH1 MAP4K1 ABCD2 TDRD12

1.01e-041511365f13a117ae26ae525da4f3e837d8f204d00dc6ee3
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PTCH1 WDFY4 PHGDH TBC1D9 FFAR4

1.25e-0415813656811dc4f101dfa9a9cc13d949760d43aa522bf3b
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PRLHR APOBEC3G DENND1C CD226 MAP4K1

1.28e-041591365bf8ff9251bcb64b2b9d6dd93461aec97659686ec
ToppCellPND03-Immune-Immune_Myeloid-DC-cDC1-cDC1_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C9orf40 WDFY4 TBC1D9 FFAR4 EFR3A

1.36e-0416113655cb91ae9674b370a27be0d5852c3816b4434239e
ToppCelldroplet-Heart-nan-24m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDFY4 FFAR4 CD226 MAP4K1 LY75

1.36e-0416113657e60001637ef0f6fc67ef8a36ab80ebb25b0b0ab
ToppCellfacs-Trachea-3m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

WDFY4 CLEC12A TBC1D9 CD226 MAP4K1

1.48e-0416413655ca7b69684a8bb12dd0b45e7ad94e30d16ed01ce
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MC4R NMUR2 ANKRD50 PTCH1 EDNRA

1.53e-04165136501c6355177d79b4523c8b20366e20b2b62c6d08d
ToppCellfacs-Heart-RA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDFY4 PHGDH CXCR5 MAP4K1 ALK

1.53e-04165136536415924d05373e9dd3665be599f4f3f40bf0497
ToppCellFetal_29-31_weeks-Immune-dendritic_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SCN11A APOBEC3G IL18R1 WDFY4 FFAR4

1.53e-041651365d8b0a9b6f704b98e8f0412c11739879a26c036e2
ToppCellfacs-Heart-RA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDFY4 PHGDH CXCR5 MAP4K1 ALK

1.53e-04165136556310fddd3d8e4afdfde066d26cee9747e5b8c6a
ToppCelldroplet-Spleen-nan-3m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC12A TBC1D9 FFAR4 TGM2 SCN3A

1.57e-041661365c1f18de4a1a2b6cdc703e6d29d136e1134fcbdf3
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|356C / Donor, Lineage, Cell class and subclass (all cells)

INTS1 TYSND1 CDAN1 TYW5 LY75

1.57e-041661365c4f7ea1cad962b1d6ad77423d15978b68a0d6f1d
ToppCelldroplet-Bladder-nan-3m-Hematologic-granulocyte-monocyte_progenitor|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND1C WDFY4 CLEC12A CD226 MAP4K1

1.57e-041661365e01c720de6d4ca144c55378e023e718a64bf32f6
ToppCelldroplet-Spleen-nan-3m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC12A TBC1D9 FFAR4 TGM2 SCN3A

1.57e-04166136594c30d6ca179d0cb02a5ed0093c5a2871e17ae50
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor|lymph-node_spleen / Manually curated celltypes from each tissue

PALD1 OPRK1 MLC1 NYNRIN SCN3A

1.61e-041671365cb396f3edb9e8fdc316091e8e193dbba50e0be0c
ToppCell3'_v3-GI_small-bowel-Lymphocytic_B-Memory_B_cells|GI_small-bowel / Manually curated celltypes from each tissue

WDFY4 TBC1D9 CXCR5 SCN3A TMEM132A

1.66e-0416813658e025bb0541746e232b77ac0e31412ae71420c47
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STT3B QSOX1 TGM2 NOX1 ACKR3

1.66e-0416813653bddf411a60137a8883fc9e77586e4719b0d6067
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_B-B_cells-B-cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRM4 WDFY4 TBC1D9 CXCR5 MAP4K1

1.66e-041681365eeb381b62c7ba263af96de1194ed59e57b6ca3ae
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_B-B_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRM4 WDFY4 TBC1D9 CXCR5 MAP4K1

1.66e-041681365063d0368d656962b335154c230bdcd9236e7c9ad
ToppCell3'_v3-GI_small-bowel-Lymphocytic_B|GI_small-bowel / Manually curated celltypes from each tissue

WDFY4 TBC1D9 CXCR5 SCN3A TMEM132A

1.66e-0416813655535c1b8b7fde7b59a1bc0580cebdfa963aa1c39
ToppCellLPS-antiTNF-Myeloid-Dendritic_cells-mDC|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

WDFY4 CLEC12A TBC1D9 CD226 MAP4K1

1.66e-0416813652dca1c4a33b6da9357fa3b2a523af19baab1c21c
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STT3B QSOX1 TGM2 NOX1 ACKR3

1.66e-041681365b6d948857ee652351ddbe383b75fdd1721cd8721
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_B|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRM4 WDFY4 TBC1D9 CXCR5 MAP4K1

1.66e-041681365a7c4251d8a83bc30196a444028a35c17c24dc291
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Sgol2a_(Very_small_cluster)|Striatum / BrainAtlas - Mouse McCarroll V32

SYT9 RWDD3 GPR101 BIRC6 NOX1

1.71e-041691365c3bf0cb67f200d02d5a021754e9b2a68d23ea168
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Sgol2a_(Very_small_cluster)--|Striatum / BrainAtlas - Mouse McCarroll V32

SYT9 RWDD3 GPR101 BIRC6 NOX1

1.71e-0416913655375eb52ebadccb7bfff997a11985f23e81014d6
ToppCellfacs-Marrow-KLS-3m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GNT9 TMPRSS6 DCST1 NOX1 KCNMB4

1.71e-041691365b798b91567d2f49082e2d8a337169f241c8d2080
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Sgol2a_(Very_small_cluster)-|Striatum / BrainAtlas - Mouse McCarroll V32

SYT9 RWDD3 GPR101 BIRC6 NOX1

1.71e-0416913651c132d21255f5a5174ac38db4e91927f9093418e
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

WDFY4 TBC1D9 FFAR4 LY75 ABCD2

1.85e-041721365584af6537685cb459bf0fc298e6f46872016c116
ToppCellLPS-IL1RA-Myeloid-Dendritic_cells-mDC|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

APOBEC3G WDFY4 CLEC12A CD226 MAP4K1

1.85e-041721365cc0e2a45fa74ee19e41612c3615729462474003a
ToppCellfacs-Trachea-18m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

WDFY4 CLEC12A TBC1D9 FFAR4 MAP4K1

1.85e-041721365eaba10a4d4eaab42ad2e2da65ebb20b50edaf815
ToppCellfacs-Aorta-Heart-3m-Myeloid|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDFY4 CLEC12A TBC1D9 FFAR4 MAP4K1

1.90e-041731365513b4d31bcfb269556c6b4cc389865fb12e52c4f
ToppCellfacs-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

WDFY4 CLEC12A TBC1D9 FFAR4 MAP4K1

1.95e-0417413656688424fc4e40c3c4a89669a2bc79369a726f1e6
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

EOGT EDNRA TGM2 COL18A1 FRY

1.95e-041741365015d3742d3d79a57413a333f00ef2d380a9848dd
ToppCellmetastatic_Brain-Myeloid_cells-CD141+_DCs|Myeloid_cells / Location, Cell class and cell subclass

IL18R1 WDFY4 CD226 MAP4K1 TACR1

1.95e-0417413655ec8a48a390379d6c422120dce46437a77da67cc
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRTN3 FFAR4 MAP4K1 CPSF1 ABCD2

2.01e-0417513653bca1aac2a2a1f46753b5f9462888f144ed8327b
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A2 TMPRSS6 ADORA1 QSOX1 COL18A1

2.01e-0417513655c38d4b6c03473d841e6203a7efaa6dcb2d59386
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANO9 MC1R APOBEC3G PCNX2 CD226

2.01e-04175136526bd957498e41a3f1ffa60d3effa27ca8c4ba631
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMPRSS6 GRM4 FFAR4 OPRK1 SCTR

2.06e-041761365d54543510c804474c5c32e007cd699e75fc5aaba
ToppCellfacs-Lung-EPCAM-18m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDFY4 CLEC12A TBC1D9 FFAR4 MAP4K1

2.11e-0417713657bc92314b22a876296a4e2db51e7fb0fdfd69379
ToppCellfacs-Lung-EPCAM-18m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDFY4 CLEC12A TBC1D9 FFAR4 MAP4K1

2.11e-0417713653cb96d7d56c9ff90f1f8a6caaf49e580e2524c7d
ToppCellcontrol-NK_CD56bright|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CCNJL APOBEC3G IL18R1 MLC1 CD226

2.17e-041781365f3d0bc9a39ed94785676f10c285c5b031bc93aae
ToppCellControl-T/NK-NK|Control / Disease group,lineage and cell class (2021.01.30)

APOBEC3G IL18R1 MLC1 CD226 KCNMB4

2.17e-041781365079fd19bdeed86bf985c4083af432432d66ad546
ToppCellfacs-Heart-LV-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EDNRA FRY SCN3A KCNT1 TDRD12

2.23e-0417913658da6863edc756540bb097cc7221c1408640d9bb4
ToppCellfacs-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

WDFY4 CLEC12A TBC1D9 FFAR4 MAP4K1

2.23e-04179136533ed9270d257895ff3b40df2c1af878119c9f492
ToppCellfacs-Heart-LV-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EDNRA FRY SCN3A KCNT1 TDRD12

2.23e-041791365f39c13c99a07d009cc677e363ffe089089c64916
ToppCellfacs-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

WDFY4 CLEC12A TBC1D9 FFAR4 MAP4K1

2.23e-041791365b7a2429d07d7146b32b3552a5f2a2542105a71e0
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRTN3 WDFY4 CLEC12A FFAR4 KCNT1

2.29e-0418013656ac62bf1251978c8c12e715f7b73144fca619794
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHBDD1 PTCH1 CLEC12A MFSD12 TBC1D9

2.29e-041801365be10fe5bf7c3a671c42704ce7dd8226ab6896794
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHBDD1 PTCH1 CLEC12A MFSD12 TBC1D9

2.29e-0418013653b747a517ce75ef2ff09011c037dad7b01ed3e03
ToppCellcontrol-Lymphoid-B_cell|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DENND1C WDFY4 CXCR5 MAP4K1 SCN3A

2.34e-041811365e414303bb90e5fe7b667c2acf9a50f8694b90e54
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SLC17A2 MC2R PTCH1 EDNRA TMEM132A

2.34e-041811365d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_bright-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CCNJL APOBEC3G RNF213 IL18R1 ALK

2.34e-0418113659c4f9abb9335da2b07644bca8faff1baa1bb9f5b
ToppCelldroplet-Lung-LUNG-30m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHGDH TBC1D9 FFAR4 LY75 ABCD2

2.34e-0418113658fcdab61fad2efd324d2b27c58f5a594f1dc15de
ToppCell11.5-Distal-Immune-Immune|Distal / Age, Tissue, Lineage and Cell class

DENND1C WDFY4 CLEC12A MAP4K1 SCN3A

2.34e-041811365193ee02f547a218b2fc13e1174ea4cff4f8a3450
ToppCellfacs-Lung-EPCAM-24m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDFY4 CLEC12A TBC1D9 FFAR4 MAP4K1

2.40e-0418213659465238ac806fce46dfe1a141e83893f23eb4afb
ToppCellNS-control-d_0-4-Lymphoid-B_cell|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DENND1C WDFY4 CXCR5 MAP4K1 SCN3A

2.40e-0418213654b9b55154a79992112c1c467e8752c3cdbb541d9
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam____kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS6 COL18A1 TMEM132A SCTR ST8SIA5

2.40e-041821365fe4fb213dc0ca482b0f94097fe1b0a51fc2690e2
ToppCellHSPCs-Neutro_prog.|World / Lineage and Cell class

PRTN3 CLEC12A PHGDH STT3B ABCD2

2.40e-041821365f2512354b90f55bf4172c28084bf52cf79e41d8a
ToppCellfacs-Aorta-Heart-3m-Myeloid-macrophage|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDFY4 CLEC12A TBC1D9 FFAR4 MAP4K1

2.40e-041821365df26388c0c46d1c4775103c8e802937b4d4e7470
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHGDH TBC1D9 FFAR4 LY75 ABCD2

2.40e-041821365be48ce85991bceeff938ba080e6bf9cc62176b05
ToppCellfacs-Aorta-Heart-3m-Myeloid-leukocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDFY4 CLEC12A TBC1D9 FFAR4 MAP4K1

2.47e-041831365062ec08d66c923f90fee771b1bf8d98bdc7e6c1b
ComputationalGenes in the cancer module 288.

EDNRA OPRK1 CXCR5 AGTR2 TACR1

2.80e-0637665MODULE_288
ComputationalGenes in the cancer module 289.

DRD3 EDNRA OPRK1 CXCR5 ADORA1 ADORA2A SCTR

1.02e-05124667MODULE_289
ComputationalGenes in the cancer module 146.

DRD3 HTR2B EDNRA OPRK1 CXCR5 ADORA2A

3.61e-05102666MODULE_146
ComputationalGPCR signaling pathways (immune and neuro).

DRD3 EDNRA OPRK1 CXCR5 ADORA1

2.20e-0490665MODULE_375
ComputationalNeighborhood of JAG1

PIGB TMPRSS6 MC2R MC5R COL18A1

2.83e-0495665MORF_JAG1
ComputationalNeighborhood of SMARCD1

SLC17A2 AANAT TCF20 GRM4 ADORA2A

4.50e-04105665GCM_SMARCD1
ComputationalGenes in the cancer module 134.

EDNRA OPRK1 CXCR5

7.97e-0430663MODULE_134
Drugtetradotoxin

SCN11A DRD2 DRD3 HTR2B MLNR COX8A PTCH1 GRM4 EDNRA OPRK1 ADORA1 ADORA2A SCN3A SCN10A KCNMB4 TACR1

7.59e-0942813816CID000020382
Drug[11c]mpdx

DRD2 DRD3 ADORA1 ADORA2A

1.92e-0861384CID005461877
Drug[11c]tmsx

DRD2 DRD3 ADORA1 ADORA2A

1.59e-0791384CID005461878
DrugA804090

MC2R MC4R TACR1

2.18e-0731383CID002724878
DrugSB-277011

DRD2 DRD3 HTR2B

2.18e-0731383CID005311096
DrugLys-pro-val

MC1R MC2R MC4R MC5R

2.64e-07101384CID000125672
DrugAC1L9NAZ

DRD2 MC1R MC2R MC4R TBC1D9 OPRK1 ADORA1 ADORA2A SCTR TACR1

3.71e-0719813810CID000449606
DrugAC1L1CBF

DRD2 DRD3 MC1R MC2R MC4R MC5R EDNRA OPRK1 ADORA1 ADORA2A SCTR TACR1

1.01e-0633613812CID000001822
DrugA 86929

DRD2 DRD3 EDNRA ADORA1

1.67e-06151384ctd:C095427
Drugpentazocine HCl

MC1R MC2R MC4R MC5R OPRK1

1.84e-06341385CID000004736
Drugembitol

MC1R MC2R MC4R

2.16e-0651383CID000005928
DrugAH 21-132

MC1R MC2R MC4R MC5R ADORA1

2.84e-06371385CID003035793
DrugGTP[S]

DRD2 OXER1 DRD3 MLNR GRM4 OPRK1 ADORA1 ADORA2A TGM2 MLC1 SCN3A AGTR2 SCN10A TACR1 GPR45

3.16e-0659113815CID000001764
Drugforskolin from Coleus forskohlii

AANAT PRLHR DRD2 OXER1 DRD3 MC1R MC2R MC4R MC5R NMUR2 PTCH1 GRM4 EDNRA TBC1D9 OPRK1 ADORA1 ADORA2A SCN3A SCN10A SCTR

3.19e-06101313820CID000003413
Drugspirodecanone

DRD2 DRD3 HTR2B ADORA1

3.70e-06181384CID000070556
DrugHis-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2

MC1R MC2R MC4R

4.30e-0661383CID003010021
DrugSB 200646A

DRD2 HTR2B MC2R MC4R

4.67e-06191384CID000126769
Drugthulium

DRD2 MLNR MC1R MC2R MC4R FFAR4 OPRK1

5.18e-061111387CID000023961
Drugdeoxycorticosterone

PALD1 HTR2B MC1R MC2R MC4R MC5R EDNRA

5.18e-061111387CID000006166
Drug4pal

MC1R MC2R MC4R MC5R

5.81e-06201384CID005748175
DrugActh (4-10)

MC1R MC2R MC4R MC5R

7.14e-06211384CID000123787
DrugActh (6-9)

MC1R MC2R MC4R

7.49e-0671383CID000160744
Drugflumezapine

DRD2 DRD3 HTR2B

7.49e-0671383CID000043602
DrugActh(11-24)

MC1R MC2R MC4R MC5R

8.68e-06221384CID003037130
DrugPL 0

MC1R MC2R MC4R PHGDH

1.25e-05241384CID000016157
Drugacetylcholine

DRD2 DRD3 MLNR EDNRA OPRK1 ADORA1 ADORA2A NOX1 AGTR2 KCNMB4 TACR1

1.31e-0536113811CID000000187
Drugfenfluramine

HTR2B MC1R MC2R MC4R BIRC6 SCN3A SCN10A ADAM17

1.33e-051781388CID000003337
Drugisopentenyl diphosphate

CXCR5 EBP KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5

1.71e-05891386CID000001195
DrugShu 9119

MC1R MC2R MC4R MC5R

1.74e-05261384CID006440621
DrugHaatpln

MC1R MC2R MC4R

1.78e-0591383CID005487257
Druglysine salicylate

MC1R MC2R MC4R

1.78e-0591383CID003080858
DrugNIASP

DRD2 DRD3 HTR2B

1.78e-0591383CID006439184
Drugprazosin

AANAT DRD2 DRD3 HTR2B EDNRA OPRK1 ADORA1 ADORA2A

2.39e-051931388CID000004893
Drugindole

MC1R MC4R MC5R

2.53e-05101383ctd:C030374
Drug2-(di-n-propylamino)tetralin

DRD2 DRD3 PHGDH

2.53e-05101383CID000090285
DrugStreptomycin sulfate [3810-74-0]; Up 200; 2.8uM; MCF7; HT_HG-U133A

SCN11A MLNR MC5R EDNRA CNIH3 NOX1 CD226 GPR45

2.77e-0519713883195_UP
Drugphentolamine

AANAT DRD2 DRD3 HTR2B OPRK1 ADORA1 ADORA2A TACR1

3.08e-052001388CID000005775
DrugHis-D-Trp-D-Lys-Trp-D-Phe-Lys-NH2

MC1R MC2R MC4R

3.47e-05111383CID005311279
DrugL-368,899

MC1R MC2R MC4R

3.47e-05111383CID000132857
Drugmesulergine

DRD2 OXER1 DRD3 HTR2B

3.58e-05311384CID000068848
DrugSulpiride

DRD2 DRD3

3.65e-0521382DB00391
DrugN-n-propyl-N-phenylethyl-4(3-hydroxyphenyl)ethylamine hydrochloride

DRD2 DRD3

3.65e-0521382ctd:C016868
Drug5-methoxy-1-methyl-2-(n-propylamino)tetralin

DRD2 DRD3

3.65e-0521382ctd:C051171
DrugCGS 15855A

DRD2 DRD3

3.65e-0521382ctd:C051347
Drug(5,6-dimethoxyindan-2-yl)dipropylamine

DRD2 DRD3

3.65e-0521382ctd:C086335
DrugDomperidone

DRD2 DRD3

3.65e-0521382DB01184
DrugO265

ADORA1 ADORA2A

3.65e-0521382CID000006871
DrugUH 232

DRD2 DRD3

3.65e-0521382ctd:C045971
Drug4,4a,5,6,7,8,8a,9-octahydro-5-propyl-1H-pyrzolo(3,4-g)quinoline

DRD2 DRD3

3.65e-0521382ctd:C416545
Drug5-(5-amino-3-(4-fluorophenyl)pyrazin-2-yl)-1-isopropylprydine-2(1H)-one

ADORA1 ADORA2A

3.65e-0521382ctd:C524699
Drug6-amino-1,3-dimethyluracil

ADORA1 ADORA2A

3.65e-0521382CID000081152
Drug3-(3-cyanophenyl)-N-n-propylpiperidine

DRD2 DRD3

3.65e-0521382ctd:C094012
Drugiodosulpride

DRD2 DRD3

3.65e-0521382ctd:C045105
Drugfluoroclebopride

DRD2 DRD3

3.65e-0521382ctd:C083673
Drug2-amino-4-phenyl-8-pyrrolidin-1-ylmethylindeno(1,2-d)pyrimidin-5-one

ADORA1 ADORA2A

3.65e-0521382ctd:C562225
Drugtrimethoxymethane

MC2R MC4R

3.65e-0521382CID000009005
DrugGR 218231

DRD2 DRD3

3.65e-0521382ctd:C408390
DrugN-(4-(2-(4-(3-cyano-5-trifluoromethylphenyl)piperazin-1-yl)ethyl)cyclohexyl)-3-pyridinesulfonic amide

DRD2 DRD3

3.65e-0521382ctd:C539157
DrugPiribedil

DRD2 DRD3

3.65e-0521382ctd:D010891
DrugAC1L31N6

DRD2 DRD3

3.65e-0521382CID000132830
DrugYM-09151-2

AANAT DRD2 DRD3 HTR2B

4.07e-05321384CID000004452
DrugnM-1

HTR2B MLNR NMUR2 EDNRA OPRK1 ADORA2A TACR1

4.55e-051551387CID000445754
DrugChlorprothixene

DRD2 DRD3 HTR2B

4.61e-05121383DB01239
Drugocaperidone

DRD2 DRD3 HTR2B

4.61e-05121383CID000071351
DrugEN-1530

NPBWR1 PRLHR DRD2 DRD3 GRM4 OPRK1 ADORA1 EBP TACR1

5.15e-052781389CID000004425
DrugA-I-J

MC4R OPRK1 ADORA1 ADAM17

5.20e-05341384CID000449208
Drugatropine sulfate

DRD2 DRD3 HTR2B MLNR MC4R OPRK1 ADORA1 ADORA2A SCTR TACR1

5.23e-0534713810CID000003661
DrugSKF 38393

AANAT DRD2 DRD3 OPRK1 ADORA1 ADORA2A

5.68e-051101386CID000001242
DrugBim 22015

MC1R MC2R MC4R

5.96e-05131383CID000132380
Drugl-stepholidine

DRD2 DRD3 HTR2B TACR1

6.55e-05361384CID000005290
DrugLisuride

DRD2 DRD3 HTR2B

7.55e-05141383DB00589
DrugPramipexole

DRD2 DRD3 HTR2B

7.55e-05141383DB00413
DrugRopinirole

DRD2 DRD3 HTR2B

7.55e-05141383DB00268
Drugnaphthyridine

ADORA1 ADORA2A TGM2

7.55e-05141383CID000136069
DrugYM348

HTR2B MC2R MC4R

7.55e-05141383CID003045225
DrugCY 208-243

DRD2 DRD3 ADORA2A

7.55e-05141383CID000058144
DrugSCH 23390

AANAT DRD2 DRD3 HTR2B OPRK1 ADORA2A

7.64e-051161386CID000005018
Drugnorbiotin

DRD2 DRD3 GRM4 ADORA1 TACR1

7.68e-05721385CID000446903
Drugpipamperone

AANAT DRD2 DRD3 HTR2B

8.13e-05381384CID000004830
DrugMK-801

AANAT DRD2 DRD3 PTCH1 GRM4 OPRK1 ADORA1 ADORA2A TACR1

8.33e-052961389CID000001207
DrugNicorette

AANAT DRD2 DRD3 HTR2B MC1R GRM4 EDNRA OPRK1 ADORA1 ADORA2A SCN3A SCN10A

9.39e-0552913812CID000000942
DrugCabergoline

DRD2 DRD3 HTR2B

9.40e-05151383DB00248
DrugEnkephalin, Ala(2)-MePhe(4)-Gly(5)-

OPRK1 ADORA1 ADORA2A

9.40e-05151383ctd:D020875
DrugApomorphine

DRD2 DRD3 HTR2B

9.40e-05151383DB00714
Drugmitragynine

DRD2 OPRK1 ADORA2A

9.40e-05151383ctd:C001801
DrugGabrene

DRD2 DRD3 PTCH1 ADGRE5

9.97e-05401384CID005361323
Drugmethiothepin

DRD2 OXER1 DRD3 HTR2B TACR1

1.06e-04771385CID000004106
Drug(1-(2-(bis(4-fluorophenyl)methoxy)ethyl)-4-(3-hydroxy-3-phenylpropyl) piperazinyl decanoate)

DRD2 DRD3

1.09e-0431382ctd:C461261
Drug9-chloro-2-(2-furyl)-5-phenylacetylamino(1,2,4)triazolo(1,5-c)quinazoline

ADORA1 ADORA2A

1.09e-0431382ctd:C110041
DrugDP-6OH-3CA

DRD2 DRD3

1.09e-0431382CID000086146
DrugNeuriplege

DRD2 DRD3

1.09e-0431382CID000065750
Drug7-(N,N-dipropylamino)-5,6,7,8-tetrahydronaphtho(2,3-b)dihydro-2,3-furan

DRD2 DRD3

1.09e-0431382ctd:C090812
DrugTheobromine

ADORA1 ADORA2A

1.09e-0431382DB01412
Drug1-allylisoguanosine

ADORA1 ADORA2A

1.09e-0431382CID006438736
DrugKetamine

DRD2 TACR1

1.09e-0431382DB01221
Drug3,7-dimethyl-1-propargylxanthine

ADORA1 ADORA2A

1.09e-0431382ctd:C057837
Drug7-hydroxy-2-N,N-dipropylaminotetralin

DRD2 DRD3

1.09e-0431382ctd:C031349
Drug2-PEMA

ADORA1 ADORA2A

1.09e-0431382CID003025817
Drug3-N-methylspiperone

DRD2 DRD3

1.09e-0431382ctd:C039167
Drugquinelorane

DRD2 DRD3

1.09e-0431382ctd:C047726
DiseaseParkinson's disease (implicated_via_orthology)

NPBWR1 NPBWR2 PRLHR DRD2 DRD3 PTCH1 OPRK1 NOX1

5.99e-071571338DOID:14330 (implicated_via_orthology)
DiseaseVentricular Dysfunction

ADORA1 ADORA2A IGF2R

4.93e-0681333C0242973
DiseaseWithdrawal Symptoms

DRD2 OPRK1 ADORA1 ADORA2A TACR1

6.53e-06581335C0087169
DiseaseDrug Withdrawal Symptoms

DRD2 OPRK1 ADORA1 ADORA2A TACR1

6.53e-06581335C0086189
DiseaseSubstance Withdrawal Syndrome

DRD2 OPRK1 ADORA1 ADORA2A TACR1

6.53e-06581335C0038587
DiseaseDepressive disorder

AANAT DRD2 DRD3 MC1R MC4R OPRK1 ADORA2A TACR1 ALK

6.90e-062891339C0011581
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN11A SCN3A SCN10A

1.05e-05101333DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN11A SCN3A SCN10A

1.05e-05101333DOID:0080422 (implicated_via_orthology)
DiseaseBrain Tumor, Primary

EML4 PTCH1 TGM2 ALK

1.46e-05331334C0750974
DiseasePrimary malignant neoplasm of brain

EML4 PTCH1 TGM2 ALK

1.46e-05331334C0750979
DiseaseRecurrent Brain Neoplasm

EML4 PTCH1 TGM2 ALK

1.46e-05331334C0750977
DiseaseBenign neoplasm of brain, unspecified

EML4 PTCH1 TGM2 ALK

1.46e-05331334C0496899
DiseaseNeoplasms, Intracranial

EML4 PTCH1 TGM2 ALK

1.46e-05331334C1527390
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN11A SCN3A SCN10A

1.91e-05121333DOID:0060170 (implicated_via_orthology)
DiseaseMental Depression

AANAT DRD2 DRD3 MC1R MC4R OPRK1 TACR1 ALK

2.10e-052541338C0011570
DiseaseHypertensive disease

DRD2 HTR2B MC2R EDNRA TGM2 AGTR2 TACR1

2.58e-051901337C0020538
DiseaseMalignant neoplasm of brain

EML4 PTCH1 TGM2 ALK

2.59e-05381334C0153633
DiseaseBrain Neoplasms

EML4 PTCH1 TGM2 ALK

2.87e-05391334C0006118
DiseaseAllodynia

SCN11A DRD3 MC1R SCN10A TACR1

4.00e-05841335C0458247
DiseaseMechanical Allodynia

SCN11A DRD3 MC1R SCN10A TACR1

4.00e-05841335C2936719
DiseaseHyperalgesia, Secondary

SCN11A DRD3 MC1R SCN10A TACR1

4.00e-05841335C0751212
DiseaseHyperalgesia, Primary

SCN11A DRD3 MC1R SCN10A TACR1

4.00e-05841335C0751211
DiseaseHyperalgesia, Thermal

SCN11A DRD3 MC1R SCN10A TACR1

4.00e-05841335C0751214
DiseaseTactile Allodynia

SCN11A DRD3 MC1R SCN10A TACR1

4.00e-05841335C0751213
DiseaseHyperalgesia

SCN11A DRD3 MC1R SCN10A TACR1

4.00e-05841335C0020429
DiseaseDisruptive, Impulse Control, and Conduct Disorders

DRD2 DRD3

6.03e-0531332C0021122
DiseasePrimary Erythermalgia

SCN11A SCN10A

6.03e-0531332C0014805
DiseaseEpilepsies, Partial

SCN3A KCNT1

6.03e-0531332C0014547
DiseasePAROXYSMAL EXTREME PAIN DISORDER

SCN11A SCN10A

6.03e-0531332C1833661
DiseaseIntermittent Explosive Disorder

DRD2 DRD3

6.03e-0531332C0021776
DiseaseSeizures, Focal

DRD2 DRD3 OPRK1 ADORA2A MLC1

1.11e-041041335C0751495
DiseaseTonic - clonic seizures

DRD2 DRD3 OPRK1 ADORA2A MLC1

1.11e-041041335C0494475
Diseasefocal epilepsy (is_implicated_in)

SCN3A NPRL3

1.20e-0441332DOID:2234 (is_implicated_in)
Diseasethioproline measurement

TMPRSS6 SLC23A3

1.20e-0441332EFO_0801012
DiseaseChediak-Higashi syndrome (implicated_via_orthology)

WDFY4 WDFY3

1.20e-0441332DOID:2935 (implicated_via_orthology)
DiseaseEtat Marbre

DRD2 DRD3 ADORA2A

1.48e-04231333C0266487
DiseaseAnhedonia

DRD2 MC4R OPRK1

1.69e-04241333C0178417
DiseaseSchizophrenia

DRD2 DRD3 MC5R GRM4 IL18R1 CNIH3 ADORA1 ADORA2A TGM2 SLC26A8 MLC1 ALK SLC23A3

1.85e-0488313313C0036341
Diseaseheroin dependence (biomarker_via_orthology)

DRD2 DRD3

2.00e-0451332DOID:9976 (biomarker_via_orthology)
DiseaseBradycardia

DRD2 ADORA1 TACR1

2.16e-04261333C0428977
DiseaseAlcoholic Intoxication, Chronic

DRD2 DRD3 NMUR2 OPRK1 TACR1 ALK CDH10

2.22e-042681337C0001973
DiseaseMovement Disorders

DRD2 DRD3 ADORA2A

3.00e-04291333C0026650
DiseaseChild Development Disorders, Specific

DRD2 WDFY4 KCNT1

3.00e-04291333C0085997
DiseaseChild Development Deviations

DRD2 WDFY4 KCNT1

3.00e-04291333C0085996
DiseaseDevelopmental Disabilities

DRD2 WDFY4 KCNT1

3.32e-04301333C0008073
DiseaseHyperkinesia

DRD2 DRD3 ADORA2A

4.04e-04321333C3887506
DiseaseHyperkinesia, Generalized

DRD2 DRD3 ADORA2A

4.04e-04321333C0751217
DiseaseCongenital Pain Insensitivity

SCN11A SCN10A

4.17e-0471332C0002768
DiseaseHereditary Sensory Autonomic Neuropathy, Type 5

SCN11A SCN10A

4.17e-0471332C0020075
DiseaseRecurrent depression

DRD2 DRD3

7.11e-0491332C0221480
DiseaseDelirium

DRD2 DRD3

8.86e-04101332C0011206
DiseaseMood Disorders

DRD2 DRD3 OPRK1 ADORA2A TACR1

1.01e-031681335C0525045
Diseasechildhood trauma measurement, smoking behaviour measurement

NPBWR1 OPRK1 COL18A1

1.11e-03451333EFO_0005671, EFO_0007979
DiseaseGeneralized seizures

DRD2 DRD3 OPRK1 ADORA2A

1.15e-031011334C0234533
DiseaseClonic Seizures

DRD2 DRD3 OPRK1 ADORA2A

1.15e-031011334C0234535
DiseaseConvulsive Seizures

DRD2 DRD3 OPRK1 ADORA2A

1.15e-031011334C0751494
DiseaseSeizures, Sensory

DRD2 DRD3 OPRK1 ADORA2A

1.15e-031011334C0751496
DiseaseNon-epileptic convulsion

DRD2 DRD3 OPRK1 ADORA2A

1.15e-031011334C0751056
DiseaseAtonic Absence Seizures

DRD2 DRD3 OPRK1 ADORA2A

1.15e-031011334C0751123
DiseaseComplex partial seizures

DRD2 DRD3 OPRK1 ADORA2A

1.15e-031011334C0149958
DiseaseSingle Seizure

DRD2 DRD3 OPRK1 ADORA2A

1.15e-031011334C0751110
DiseaseNonepileptic Seizures

DRD2 DRD3 OPRK1 ADORA2A

1.15e-031011334C3495874
DiseaseVisual seizure

DRD2 DRD3 OPRK1 ADORA2A

1.15e-031011334C0270824
DiseaseEpileptic drop attack

DRD2 DRD3 OPRK1 ADORA2A

1.15e-031011334C0270846
DiseaseVertiginous seizure

DRD2 DRD3 OPRK1 ADORA2A

1.15e-031011334C0422855
DiseaseGustatory seizure

DRD2 DRD3 OPRK1 ADORA2A

1.15e-031011334C0422854
DiseaseSeizures, Somatosensory

DRD2 DRD3 OPRK1 ADORA2A

1.15e-031011334C0422850
DiseaseOlfactory seizure

DRD2 DRD3 OPRK1 ADORA2A

1.15e-031011334C0422853
DiseaseSeizures, Auditory

DRD2 DRD3 OPRK1 ADORA2A

1.15e-031011334C0422852
DiseaseGeneralized Absence Seizures

DRD2 DRD3 OPRK1 ADORA2A

1.15e-031011334C4505436
DiseaseJacksonian Seizure

DRD2 DRD3 OPRK1 ADORA2A

1.15e-031011334C0022333
DiseaseEpileptic Seizures

DRD2 DRD3 OPRK1 ADORA2A

1.15e-031011334C4317109
DiseaseAbsence Seizures

DRD2 DRD3 OPRK1 ADORA2A

1.19e-031021334C4316903
DiseaseConvulsions

DRD2 DRD3 OPRK1 ADORA2A

1.19e-031021334C4048158
DiseaseTonic Seizures

DRD2 DRD3 OPRK1 ADORA2A

1.19e-031021334C0270844
DiseaseMyoclonic Seizures

DRD2 DRD3 OPRK1 ADORA2A

1.28e-031041334C4317123
DiseaseLenticulostriate Disorders

DRD2 DRD3

1.29e-03121332C0750951
DiseaseExtrapyramidal Disorders

DRD2 DRD3

1.29e-03121332C0015371
Diseasenicotine dependence (implicated_via_orthology)

DRD2 DRD3

1.29e-03121332DOID:0050742 (implicated_via_orthology)
DiseaseBasal Ganglia Diseases

DRD2 DRD3

1.29e-03121332C0004782
Diseasephospholipids in medium LDL measurement

TDRD15 IGF2R NYNRIN

1.42e-03491333EFO_0022183
Diseaselung disease (implicated_via_orthology)

ADORA1 ADORA2A

1.52e-03131332DOID:850 (implicated_via_orthology)
Diseasetotal lipids in LDL measurement

TDRD15 IGF2R NYNRIN

1.68e-03521333EFO_0022308
DiseaseHypotension

DRD2 ADORA1 ADORA2A

1.78e-03531333C0020649
Diseasepulmonary hypertension (implicated_via_orthology)

EDNRA NOX1 TACR1

1.88e-03541333DOID:6432 (implicated_via_orthology)
DiseaseWaxy flexibility

DRD2 ADORA1

2.04e-03151332C0233612
DiseaseDyskinesia, Medication-Induced

DRD2 DRD3

2.04e-03151332C0751088
DiseaseCatalepsy

DRD2 ADORA1

2.04e-03151332C0007370
DiseaseDyskinesia, Drug-Induced

DRD2 DRD3

2.04e-03151332C0013386
DiseaseRhabdomyosarcoma

PTCH1 ALK

2.04e-03151332C0035412
DiseaseFEV change measurement, response to bronchodilator

MC2R MC5R OR6F1

2.30e-03581333EFO_0005921, GO_0097366
Diseasephospholipids in small LDL measurement

TDRD15 IGF2R NYNRIN

2.42e-03591333EFO_0022297
Diseasehypertension (implicated_via_orthology)

DRD3 EDNRA ADORA1 AGTR2

2.73e-031281334DOID:10763 (implicated_via_orthology)
Diseaserheumatoid arthritis, ACPA-positive rheumatoid arthritis, rheumatoid factor seropositivity measurement

RGS22 WDFY4 CXCR5

2.92e-03631333EFO_0000685, EFO_0007791, EFO_0009459
DiseaseGlobal developmental delay

PIGB TCF20 INTS1 STT3B

3.14e-031331334C0557874
DiseaseSeizures

PIGB DRD2 DRD3 OPRK1 ADORA2A

3.14e-032181335C0036572
Diseasesystemic lupus erythematosus

PRSS54 SLC17A2 WDFY4 CXCR5 SLC7A8 GTF2H1 TRMT44 CD226 SCN10A TARBP1

3.41e-0379913310MONDO_0007915
DiseaseMalignant neoplasm of breast

NPBWR1 TMPRSS6 DGKE PHGDH EDNRA PIK3R4 CXCR5 GPR180 TGM2 ALK CDH10 GPR45

3.45e-03107413312C0006142
DiseaseAlcohol abuse

DRD2 DRD3 TACR1

3.47e-03671333C0085762
DiseaseCocaine Dependence

DRD2 DRD3 MC4R OPRK1

3.67e-031391334C0600427

Protein segments in the cluster

PeptideGeneStartEntry
THLLFLPDWAAVFEL

EOGT

431

Q5NDL2
VLCPAWLFLDVLFST

HTR2B

126

P41595
FLPEEAWCDLTIHLP

BIRC6

3201

Q9NR09
CWSPYHIVIFLDTLA

CXCR5

271

P32302
FPKLVTTETGWLCLH

ABCD2

96

Q9UBJ2
FLFALSWLPLHILNC

ADORA1

241

P30542
AIIVGLFALCWLPLH

ADORA2A

236

P29274
WLPLHIINCFTFFCP

ADORA2A

246

P29274
LFFPDVWHCLPTRSE

CCAR1

571

Q8IX12
SIVWVHAFPELFLSC

ATXN10

151

Q9UBB4
RHAELCFLDVIPFWK

APOBEC3G

256

Q9HC16
LLGICVWFVVDPSHS

GRM4

711

Q14833
FLAFCVWLTLPGAET

ADGRE5

6

P48960
VVLAFIICWLPFHVL

AGTR2

261

P50052
IICWLPFHVLTFLDA

AGTR2

266

P50052
FSWNLCLPTPAHFLD

CCNJL

186

Q8IV13
LVVIFALCWFPLHLS

EDNRA

311

P25101
HHEFFPPWLLLLCSA

ANKRD50

221

Q9ULJ7
HLDLLPFLEQLYCWA

DNHD1

101

Q96M86
HVALCIKLIAAWFVP

ANO9

711

A1A5B4
CILSHLPWFEVFYKL

DENND1C

96

Q8IV53
LTVPWLVEFLSFADH

CDAN1

691

Q8IWY9
LWDPNEFAVHCFKII

EFR3A

266

Q14156
RGFPCSLWVLFHFLT

QSOX1

401

O00391
EDLSCWFPPSHIFSV

JAK3

76

P52333
PFTILLFFLLHRWCS

KIR2DS2

256

P43631
FLCWGPFFLHLTLIV

MC1R

251

Q01726
FALSFSRWLCAHPEL

PALD1

446

Q9ULE6
CIWLLVLSFIGGFLH

OR5H8

141

P0DN80
FLLVFSLWSEPVVCG

SLC7A8

436

Q9UHI5
FVNCPSISLLEWHPF

NOX1

326

Q9Y5S8
PGLEAAHFWIAIPFC

OR52D1

21

Q9H346
GLETLHIWIGFPFCA

OR52E2

21

Q8NGJ4
GLDTLHIWISFPFCI

OR52E4

21

Q8NGH9
HIWISFPFCIVYLIA

OR52E4

26

Q8NGH9
TCWIFSFLLALVHIT

OR2A12

146

Q8NGT7
IALHDCVLEFWPVEL

IL18R1

76

Q13478
PFTILLFFLLHRWCS

KIR2DS4

256

P43632
VFAICWAPFHIDRLF

NMUR2

276

Q9GZQ4
PSASLDFLWACIHVP

INTS1

1691

Q8N201
LLVHCISGWDRTPLF

MTMR14

326

Q8NCE2
FIPVFLNCWLAKHAL

KCNT1

216

Q5JUK3
VHPVIWSLTSLPFDC

CPSF1

251

Q10570
HLIAAFWAPVCAFLA

MFSD6L

56

Q8IWD5
TEAWLLGPVACHLLF

FFAR4

101

Q5NUL3
ALLHAVCFSAVKEPW

PCNX2

1011

A6NKB5
HGWISIPFCFIYLTV

OR51G1

26

Q8NGK1
CLSTLPTVLGIFWFD

OR51G1

76

Q8NGK1
LTAFPGLECAHVWIS

OR51T1

16

Q8NGJ9
IFWFHLPEISFDACL

OR52A5

86

Q9H2C5
GLEAYHIWLSIPLCL

OR52B2

21

Q96RD2
LHFVHCFLPVAEGWA

MYO18A

1041

Q92614
CHPFLAWFFCLLLVP

COL18A1

381

P39060
INSWLEVSFCLPHKI

NPRL3

221

Q12980
FPFLIDGTWHHDCIL

LY75

171

O60449
PFTILLFFLLHRWCS

KIR2DS3

256

Q14952
FWPLNSHFCTALVSL

GPR101

96

Q96P66
LWFLCHPVLACISVI

GPR180

366

Q86V85
GLEATHIWISLPFCF

OR52N2

21

Q8NGI0
IDSFVIWGCATRLFP

PRTN3

216

P24158
HLAFGCILSEFWVLS

PRSS54

66

Q6PEW0
IGLPLLAFDFHWCTN

CYHR1

71

Q6ZMK1
SVAEIFDCLGPHFTW

OC90

51

Q02509
LCWTPFHLASVVALT

NPBWR2

271

P48146
ILFVGFSLCWLPHSV

GPR45

271

Q9Y5Y3
LDPAWHLLFDGCNLT

METTL7A

191

Q9H8H3
SLALFIFCIHTRPWT

OXER1

111

Q8TDS5
PFTILLFFLLHRWCS

KIR2DS5

256

Q14953
FLLLFLFWVCLPHFC

CDH10

6

Q9Y6N8
EWALGLLHVLLSCTF

DCST1

371

Q5T197
FLVCWLPYHVAVLLD

ACKR3

261

P25106
IGVFVVCWAPFFLHL

MC4R

251

P32245
VFTVCWAPFFLHLTL

MC5R

246

P33032
SCFVTFLLPAGWILS

COX8A

46

P10176
DEIVLLHCFLWPLVT

KCNMB4

166

Q86W47
LHCFLWPLVTFVVGV

KCNMB4

171

Q86W47
WGLATHPFKDLLLTC

EML4

596

Q9HC35
VFIICWLPFFITHIL

DRD2

381

P14416
WLPFFITHILNIHCD

DRD2

386

P14416
IEFLTTRAFGPLWCH

FRY

1796

Q5TBA9
TFHVPWKRLLLCDFA

C9orf40

11

Q8IXQ3
LFADGHLILWTLCSV

DGKE

16

P52429
ALCEEVLWHTSVPFA

CD226

16

Q15762
LCWFAVCGFIHLVIE

EBP

66

Q15125
FLHSVFLEGPVESWL

DNAH2

1596

Q9P225
EIFNCIFDAHVPPLW

DNAH2

4226

Q9P225
WHLVGTVCVLLSFPF

MFSD12

96

Q6NUT3
GAFIVCWLPFFLTHV

DRD3

336

P35462
LVVVLAFIICWLPFH

MLNR

301

O43193
AFIICWLPFHVGRII

MLNR

306

O43193
LLCWTPYHLSTVVAL

NPBWR1

261

P48145
PVVFLTHCNWIFSLL

NYNRIN

1371

Q9P2P1
PRAINHFFCDIAPWI

OR6F1

171

Q8NGZ6
PFTILLFFLLHRWCS

KIR2DS1

256

Q14954
CWTPIHIFILVEALG

OPRK1

286

P41145
GLEHLHAWISIPFCF

OR52K1

21

Q8NGK4
HIWISIPFCLAYTLA

OR52K2

26

Q8NGK3
GLEDVHLWISFPLCT

OR52N1

21

Q8NH53
VLFHTVRFGALSCWL

MAP4K1

686

Q92918
HPIFSLNWECVVSFL

IGF2R

901

P11717
VILWTPLLFRHFCQE

PIGB

236

Q92521
HFLDLADFPRECILW

SYT9

326

Q86SS6
WESVIYLCAAVHPII

TAS2R60

281

P59551
FISVLIFCPERWHSD

TRMT44

246

Q8IYL2
CWVELVAIHLFSPGT

RHBDD1

176

Q8TEB9
VFAVCWLPLHVFNLL

PRLHR

286

P49683
RHFLTLCPELSLGWF

AANAT

71

Q16613
LGACVVELELPSHWF

TMEM132A

181

Q24JP5
CSLAHIFPVEDLWTK

TDRD15

596

B5MCY1
LLLYWAPRFCVTHSA

RGS22

501

Q8NE09
WVIIKGCSPFLDHDV

TDRD12

16

Q587J7
WHRFLRCVLTIFPFL

SLC26A8

66

Q96RN1
TFAICWLPFHIFFLL

TACR1

256

P25103
PFTILLFFLLHRWCS

KIR3DS1

351

Q14943
HWLLLFISVVLACTF

PTCH1

1026

Q13635
ELCEEVHLFGFWAFP

ST8SIA5

311

O15466
HSFLIVFRVLCGEWI

SCN3A

931

Q9NY46
EVAQFCFTHWGLALL

SLC23A3

211

Q6PIS1
LKEIHFLAWASAFCP

B3GNT9

206

Q6UX72
IFDPTVHWLFTTCGA

ALK

676

Q9UM73
GVFIFCWAPFVLHVL

MC2R

226

Q01718
LIFWIPFSILVHCVD

ADAM17

681

P78536
SHVWRPAALFLTLLC

CLEC12A

36

Q5QGZ9
LCAALIFFAIWHIIA

CNIH3

16

Q8TBE1
FASDIAPFLCHPNLW

PIK3R4

656

Q99570
VLGHFILLFNAWCPA

TGM2

131

P21980
FLFHCGVINPSWSEL

RNF213

2201

Q63HN8
VLAAIFCRPHEWEVL

RWDD3

11

Q9Y3V2
VAVGELLRHFWSCFP

GTF2H1

466

P32780
LAAPLLILWFHLDCV

TRAV24

6

A0A0B4J272
LLCDFEVWLHAPYEL

WDFY3

1501

Q8IZQ1
FHSFLIVFRILCGEW

SCN10A

836

Q9Y5Y9
FDLHILVCTFPAGLW

STT3B

416

Q8TCJ2
HWLDIDPNFICLSGL

SPATA31D1

21

Q6ZQQ2
PAIFVALWAIARHFL

SCTR

266

P47872
ALLFPWACGTHSDVL

TBC1D9

876

Q6ZT07
TCLPLWAIFLGFFSH

SLC17A2

271

O00624
FLKAWEHSVGIICFP

WDFY4

76

Q6ZS81
PLDSNEFWVHEGCIL

TCF20

1846

Q9UGU0
PLWRDVIATFTDHCI

ZZEF1

2216

O43149
SHLLFAVGCPLLLLW

PIGO

946

Q8TEQ8
HSFLVVFRILCGEWI

SCN11A

756

Q9UI33
IWPLCDFITVHTPLL

PHGDH

196

O43175
HWCAVPILFLSKALA

TARBP1

481

Q13395
ECLAHLFSWIPLSAS

XPO6

251

Q96QU8
ICGLLPWIDNIAHIF

RHBDF2

761

Q6PJF5
LLLSCPAFWAHFARL

TYSND1

136

Q2T9J0
LEAGDVLFIPALWFH

TYW5

221

A2RUC4
ARSHFFEPGLHCWIT

TMPRSS6

691

Q8IU80
PHLSVTFFWILVACF

MLC1

226

Q15049
EHFISILGKCFDSPW

LRRC8C

156

Q8TDW0