Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
ToppCellLPS-IL1RA-Myeloid-Monocytes,_Macrophages-Neutrophils|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPFIA4 ARHGEF40

1.41e-0413962505bf5a483fc2ba69377db9850c3b26ab2f416d1
ToppCell(08)_PNEC-(2)_48hpi|(08)_PNEC / shred by cell type and Timepoint

ARHGEF40 SP140

1.47e-0414262e95d34170f5053678e0dd9793e68d93c03b05822
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SENP3 SP140

1.49e-0414362605532fc0f32979b306cbb58f8796df7d6b24828
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SENP3 SP140

1.49e-04143625cc59deb5a8af8095c1581e585eaeeecdd938621
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SENP3 SP140

1.49e-0414362360a2ea8b64e3b9084f4c4cb8beb0d44106b9edb
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AMER2 ARHGEF40

1.71e-041536283942ef63d21725fa15ed5a91481d1f9936e8f11
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Myeloid-macrophage|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIA4 SP140

1.78e-0415662c841faa1695ff577b0774f531adf1343d05dce9e
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Myeloid|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIA4 SP140

1.78e-041566221baf8c6e62bb7fd1530c2c100f73c0cecee092e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic-Mast_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AMER2 ARHGEF40

1.87e-0416062fe9970c160159b35f6599ed13c89cfb49264d554
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AMER2 SP140

1.91e-04162628ed9149ff53b285591354057055d072b203a47c8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AMER2 SP140

1.91e-04162627a05b05a33e1309fb5c0a8171db105ae68491815
ToppCellfacs-Trachea-3m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PPFIA4 SP140

1.96e-04164625ca7b69684a8bb12dd0b45e7ad94e30d16ed01ce
ToppCellfacs-Pancreas-Endocrine-18m-Hematologic-leukocyte|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIA4 SP140

2.08e-041696280089dfb1f0f4d6bdf6ca161e902b38011992dfd
ToppCelldroplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PPFIA4 ARHGEF40

2.08e-0416962b2d53159e344fad6fcdc485d5b8f6cf1bf094b1f
ToppCellfacs-Pancreas-Endocrine-18m-Hematologic|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIA4 SP140

2.08e-0416962c68a305069a149d66dfdeef2a8010f460dc1da3b
ToppCellfacs-Pancreas-Endocrine-18m-Hematologic-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIA4 SP140

2.08e-04169620e3d0b71fc21fd1de7034d13895608de5494fad8
ToppCelldroplet-Thymus-nan-21m-Myeloid-professional_antigen_presenting_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIA4 SP140

2.11e-041706229deb285d5a82c0abcc108012ca42f4b4b4d9e19
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PPFIA4 C22orf15

2.11e-041706260bbd738c12e64e483485586c30057304884f5a6
ToppCelldroplet-Thymus-nan-21m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIA4 SP140

2.11e-0417062dc35d66a9a9fe6cdd7f4ec0fe7efa49d02f2b5b2
ToppCellE16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PPFIA4 SP140

2.18e-041736220f7dfe7d92a3dbec9da9a1f3185aa10cb8f0a3c
ToppCelldroplet-Tongue-nan-24m-Myeloid-Langerhans_cell|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIA4 SP140

2.42e-04182620f06309318c064f0ebdb12a46226b90032290137
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AMER2 ARHGEF40

2.72e-041936264edc1d6fb0fe117767d494cf4a5723bf8be2804
ToppCellCV-Moderate-1|CV / Virus stimulation, Condition and Cluster

PPFIA4 SP140

2.83e-0419762e3d00d850b4d191f9592ef993c0eaadfe5710b5f
DrugPergolide mesylate [66104-23-2]; Up 200; 9.8uM; HL60; HT_HG-U133A

ARHGEF40 SP140

5.21e-04166522403_UP
DrugFenoterol hydrobromide [1944-12-3]; Up 200; 10.4uM; HL60; HT_HG-U133A

ARHGEF40 SP140

6.19e-04181522378_UP
DrugProgesterone [57-83-0]; Down 200; 12.8uM; HL60; HT_HG-U133A

PPFIA4 SENP3

6.53e-04186522426_DN
DrugGramine [87-52-5]; Up 200; 23uM; MCF7; HT_HG-U133A

ARHGEF40 SP140

6.96e-04192522799_UP
DrugLY 294002; Down 200; 10uM; PC3; HT_HG-U133A

ARHGEF40 SENP3

7.03e-04193524460_DN
DrugFamprofazone [22881-35-2]; Up 200; 10.6uM; PC3; HT_HG-U133A

PPFIA4 SP140

7.18e-04195524309_UP
DrugLY294002; Down 200; 10uM; PC3; HT_HG-U133A

ARHGEF40 SENP3

7.25e-04196525970_DN
DrugEtofenamate [30544-47-9]; Down 200; 10.8uM; HL60; HT_HG-U133A

PPFIA4 ARHGEF40

7.25e-04196522907_DN
DrugZuclopenthixol hydrochloride [633-59-0]; Down 200; 9.2uM; HL60; HT_HG-U133A

PPFIA4 ARHGEF40

7.25e-04196522936_DN
DrugAminohippuric acid [61-78-9]; Down 200; 20.6uM; HL60; HT_HG-U133A

SENP3 SP140

7.25e-04196523076_DN
DrugPiribedil hydrochloride [78213-63-5]; Up 200; 12uM; HL60; HT_HG-U133A

PPFIA4 SP140

7.25e-04196522951_UP
Drug5194442; Up 200; 20uM; PC3; HT_HG-U133A

SENP3 SP140

7.25e-04196526594_UP
DrugMebhydroline 1,5-naphtalenedisulfonate [6153-33-9]; Down 200; 4.8uM; HL60; HT_HG-U133A

PPFIA4 ARHGEF40

7.32e-04197521333_DN
DrugRetrorsine [480-54-6]; Up 200; 11.4uM; HL60; HT_HG-U133A

PPFIA4 SENP3

7.32e-04197522129_UP
DrugMianserine hydrochloride [21535-47-7]; Up 200; 13.2uM; HL60; HG-U133A

ARHGEF40 SENP3

7.32e-04197521385_UP
DrugAntimycin A [1397-94-0]; Up 200; 7.2uM; PC3; HT_HG-U133A

PPFIA4 ARHGEF40

7.40e-04198525053_UP
DrugRanitidine hydrochloride [66357-59-3]; Up 200; 11.4uM; PC3; HT_HG-U133A

PPFIA4 ARHGEF40

7.40e-04198522088_UP
DrugSulfasalazine [599-79-1]; Down 200; 10uM; PC3; HT_HG-U133A

ARHGEF40 SENP3

7.40e-04198526346_DN
DrugTolazoline hydrochloride [59-97-2]; Up 200; 20.4uM; PC3; HT_HG-U133A

PPFIA4 ARHGEF40

7.47e-04199524262_UP
DrugDehydroisoandosterone 3-acetate [853-23-6]; Down 200; 12.2uM; HL60; HT_HG-U133A

PPFIA4 SP140

7.55e-04200523097_DN
DrugAcetaminophen [103-90-2]; Down 200; 26.4uM; PC3; HT_HG-U133A

ARHGEF40 SENP3

7.55e-04200526284_DN
DrugImipenem [74431-23-5]; Up 200; 13.4uM; HL60; HG-U133A

ARHGEF40 SENP3

7.55e-04200521724_UP
DrugPolychlorinated Biphenyls

PPFIA4 SP140

7.30e-0363352ctd:D011078
Drugmercuric bromide

PPFIA4 AMER2

2.03e-02107652ctd:C042720
Drug3,4,5,3',4'-pentachlorobiphenyl

ARHGEF40 SP140

2.57e-02121952ctd:C023035

Protein segments in the cluster

PeptideGeneStartEntry
KRGLRGLFSGMRWHR

AMER2

191

Q8N7J2
GAGGKGRHRRHRAWM

ARHGEF40

276

Q8TER5
GRHRRHRAWMHQKGL

ARHGEF40

281

Q8TER5
GHNWRKRMGTRRGRH

C22orf15

121

Q8WYQ4
WRKRFRPREHHGRGG

PPFIA4

1121

O75335
FHWKLWGRHRGRRRG

SENP3

146

Q9H4L4
WGRHRGRRRGLAHPK

SENP3

151

Q9H4L4
DGGWRGAMKGRRHRQ

nan

76

Q9BRP9
KKRGHGWSRMRMRRQ

SP140

501

Q13342