Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	actin-based cell projection	PCDH15 MPP1 ABI1 MYO7A ABI2	2.03e-04	278	41	5	GO:0098858
GeneOntologyCellularComponent	postsynaptic density	SRGAP2 CLSTN2 ABI1 DST DRP2 KALRN	2.31e-04	451	41	6	GO:0014069
GeneOntologyCellularComponent	SCAR complex	ABI1 ABI2	2.45e-04	12	41	2	GO:0031209
GeneOntologyCellularComponent	asymmetric synapse	SRGAP2 CLSTN2 ABI1 DST DRP2 KALRN	3.12e-04	477	41	6	GO:0032279
GeneOntologyCellularComponent	stereocilium	PCDH15 MPP1 MYO7A	3.35e-04	69	41	3	GO:0032420
GeneOntologyCellularComponent	postsynaptic specialization	SRGAP2 CLSTN2 ABI1 DST DRP2 KALRN	4.14e-04	503	41	6	GO:0099572
GeneOntologyCellularComponent	stereocilium bundle	PCDH15 MPP1 MYO7A	4.99e-04	79	41	3	GO:0032421
GeneOntologyCellularComponent	neuron to neuron synapse	SRGAP2 CLSTN2 ABI1 DST DRP2 KALRN	5.09e-04	523	41	6	GO:0098984
GeneOntologyCellularComponent	filopodium tip	ABI1 ABI2	6.97e-04	20	41	2	GO:0032433
GeneOntologyCellularComponent	postsynapse	SRGAP2 CLSTN2 ABI1 DST DRP2 KALRN ABI2 SRGAP3	7.00e-04	1018	41	8	GO:0098794
GeneOntologyCellularComponent	glutamatergic synapse	SRGAP2 CLSTN2 ABI1 DRP2 KALRN ABI2 SRGAP3	9.56e-04	817	41	7	GO:0098978
GeneOntologyCellularComponent	chromosomal region	CDT1 ATM TNKS2 CENPC SUN2	1.33e-03	421	41	5	GO:0098687
GeneOntologyCellularComponent	condensed chromosome	CDT1 CENPC POLB SUN2	3.01e-03	307	41	4	GO:0000793
MousePheno	enlarged stomach	ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	1.44e-06	33	36	4	MP:0003883
Domain	SH3	MPP1 SRGAP2 ABI1 DST KALRN MYO7A ABI2 SRGAP3 SRGAP1	1.56e-09	216	44	9	PS50002
Domain	SH3_domain	MPP1 SRGAP2 ABI1 DST KALRN MYO7A ABI2 SRGAP3 SRGAP1	1.84e-09	220	44	9	IPR001452
Domain	SH3	MPP1 SRGAP2 ABI1 KALRN MYO7A ABI2 SRGAP3 SRGAP1	3.48e-08	216	44	8	SM00326
Domain	SH3_1	SRGAP2 ABI1 DST ABI2 SRGAP3 SRGAP1	2.24e-06	164	44	6	PF00018
Domain	Abl-interactor_HHR_dom	ABI1 ABI2	1.62e-05	3	44	2	IPR012849
Domain	Abi_HHR	ABI1 ABI2	1.62e-05	3	44	2	PF07815
Domain	FCH	SRGAP2 SRGAP3 SRGAP1	1.82e-05	22	44	3	PF00611
Domain	FCH	SRGAP2 SRGAP3 SRGAP1	1.82e-05	22	44	3	SM00055
Domain	Spectrin	DST DRP2 KALRN	2.09e-05	23	44	3	PF00435
Domain	FCH_dom	SRGAP2 SRGAP3 SRGAP1	2.09e-05	23	44	3	IPR001060
Domain	F_BAR	SRGAP2 SRGAP3 SRGAP1	2.71e-05	25	44	3	IPR031160
Domain	F_BAR	SRGAP2 SRGAP3 SRGAP1	2.71e-05	25	44	3	PS51741
Domain	Spectrin_repeat	DST DRP2 KALRN	4.27e-05	29	44	3	IPR002017
Domain	Spectrin/alpha-actinin	DST DRP2 KALRN	5.77e-05	32	44	3	IPR018159
Domain	SPEC	DST DRP2 KALRN	5.77e-05	32	44	3	SM00150
Domain	Ank_2	ANKRD20A2P ANKRD20A3P TNKS2 ANKRD20A4P ANKRD20A1	1.45e-04	215	44	5	PF12796
Domain	Ank	ANKRD20A2P ANKRD20A3P TNKS2 ANKRD20A4P ANKRD20A1	1.91e-04	228	44	5	PF00023
Domain	-	ANKRD20A2P ANKRD20A3P TNKS2 ANKRD20A4P ANKRD20A1	2.82e-04	248	44	5	1.25.40.20
Domain	ANK	ANKRD20A2P ANKRD20A3P TNKS2 ANKRD20A4P ANKRD20A1	2.98e-04	251	44	5	SM00248
Domain	ANK_REPEAT	ANKRD20A2P ANKRD20A3P TNKS2 ANKRD20A4P ANKRD20A1	3.09e-04	253	44	5	PS50088
Domain	Ankyrin_rpt-contain_dom	ANKRD20A2P ANKRD20A3P TNKS2 ANKRD20A4P ANKRD20A1	3.15e-04	254	44	5	IPR020683
Domain	ANK_REP_REGION	ANKRD20A2P ANKRD20A3P TNKS2 ANKRD20A4P ANKRD20A1	3.15e-04	254	44	5	PS50297
Domain	Ankyrin_rpt	ANKRD20A2P ANKRD20A3P TNKS2 ANKRD20A4P ANKRD20A1	3.63e-04	262	44	5	IPR002110
Domain	RhoGAP	SRGAP2 SRGAP3 SRGAP1	4.19e-04	62	44	3	SM00324
Domain	RhoGAP	SRGAP2 SRGAP3 SRGAP1	4.39e-04	63	44	3	PF00620
Domain	RHOGAP	SRGAP2 SRGAP3 SRGAP1	4.60e-04	64	44	3	PS50238
Domain	RhoGAP_dom	SRGAP2 SRGAP3 SRGAP1	4.60e-04	64	44	3	IPR000198
Domain	-	SRGAP2 SRGAP3 SRGAP1	4.60e-04	64	44	3	1.10.555.10
Domain	Rho_GTPase_activation_prot	SRGAP2 SRGAP3 SRGAP1	1.16e-03	88	44	3	IPR008936
Domain	T_SNARE	ABI1 ABI2	1.70e-03	26	44	2	PS50192
Domain	T_SNARE_dom	ABI1 ABI2	2.11e-03	29	44	2	IPR000727
Domain	Kinase-like_dom	ATM STK40 DST KALRN PRKX	8.63e-03	542	44	5	IPR011009
Pathway	REACTOME_INACTIVATION_OF_CDC42_AND_RAC1	SRGAP2 SRGAP3 SRGAP1	6.49e-07	8	33	3	M27349
Pathway	REACTOME_RAC1_GTPASE_CYCLE	SRGAP2 ABI1 KALRN ABI2 SRGAP3 SRGAP1	2.82e-06	175	33	6	MM15599
Pathway	REACTOME_RAC1_GTPASE_CYCLE	SRGAP2 ABI1 KALRN ABI2 SRGAP3 SRGAP1	3.77e-06	184	33	6	M41809
Pathway	REACTOME_RHO_GTPASE_CYCLE	SRGAP2 ABI1 DST KALRN ABI2 SRGAP3 SRGAP1	5.73e-05	439	33	7	MM15595
Pathway	REACTOME_RHO_GTPASE_CYCLE	SRGAP2 ABI1 DST KALRN ABI2 SRGAP3 SRGAP1	6.70e-05	450	33	7	M27078
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	SRGAP2 ABI1 DST CENPC KALRN ABI2 SRGAP3 SRGAP1	9.64e-05	649	33	8	MM15690
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	SRGAP2 ABI1 DST CENPC KALRN ABI2 SRGAP3 SRGAP1	1.98e-04	720	33	8	M41838
Pathway	REACTOME_SENSORY_PROCESSING_OF_SOUND_BY_OUTER_HAIR_CELLS_OF_THE_COCHLEA	PCDH15 MPP1 MYO7A	2.82e-04	55	33	3	M41823
Pathway	REACTOME_SENSORY_PROCESSING_OF_SOUND	PCDH15 MPP1 MYO7A	7.60e-04	77	33	3	M41822
Pubmed	Expression of testicular germ cell genes identified by differential display analysis.	ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	1.70e-10	8	45	4	12634303
Pubmed	Dynamic expression of the Slit-Robo GTPase activating protein genes during development of the murine nervous system.	SRGAP2 SRGAP3 SRGAP1	2.02e-09	3	45	3	19137586
Pubmed	SRGAP1 Controls Small Rho GTPases To Regulate Podocyte Foot Process Maintenance.	SRGAP2 SRGAP3 SRGAP1	4.04e-08	6	45	3	33514561
Pubmed	FNBP2 gene on human chromosome 1q32.1 encodes ARHGAP family protein with FCH, FBH, RhoGAP and SH3 domains.	SRGAP2 SRGAP3 SRGAP1	4.04e-08	6	45	3	12736724
Pubmed	Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway.	SRGAP2 SRGAP3 SRGAP1	4.04e-08	6	45	3	11672528
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	SRGAP2 DST KALRN ABI2 SRGAP3 GOLGA4	4.29e-08	151	45	6	17043677
Pubmed	Evidence for a role of srGAP3 in the positioning of commissural axons within the ventrolateral funiculus of the mouse spinal cord.	SRGAP2 SRGAP3 SRGAP1	7.06e-08	7	45	3	21655271
Pubmed	Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening.	SRGAP2 KALRN SRGAP3 SRGAP1	5.39e-07	50	45	4	19807924
Pubmed	Evidence of genetic heterogeneity in Alberta Hutterites with Usher syndrome type I.	PCDH15 MYO7A	1.64e-06	2	45	2	22690115
Pubmed	Iron-inhibited autophagy via transcription factor ZFP27 in Parkinson's disease.	ZNF585A ZNF585B	1.64e-06	2	45	2	37668106
Pubmed	Role for the Abi/wave protein complex in T cell receptor-mediated proliferation and cytoskeletal remodeling.	ABI1 ABI2	1.64e-06	2	45	2	16401422
Pubmed	Identification of SRGAP2 as a potential oncogene and a prognostic biomarker in hepatocellular carcinoma.	SRGAP2 SRGAP1	1.64e-06	2	45	2	33984363
Pubmed	The Abl interactor proteins localize to sites of actin polymerization at the tips of lamellipodia and filopodia.	ABI1 ABI2	1.64e-06	2	45	2	11516653
Pubmed	Slit-Robo GTPase-activating proteins are differentially expressed in murine dorsal root ganglia: modulation by peripheral nerve injury.	SRGAP3 SRGAP1	1.64e-06	2	45	2	22271578
Pubmed	ATM regulates Cdt1 stability during the unperturbed S phase to prevent re-replication.	CDT1 ATM	1.64e-06	2	45	2	24280901
Pubmed	Functional mutation of SMAC/DIABLO, encoding a mitochondrial proapoptotic protein, causes human progressive hearing loss DFNA64.	MYO7A DIABLO	1.64e-06	2	45	2	21722859
Pubmed	The inverse F-BAR domain protein srGAP2 acts through srGAP3 to modulate neuronal differentiation and neurite outgrowth of mouse neuroblastoma cells.	SRGAP2 SRGAP3	1.64e-06	2	45	2	23505444
Pubmed	Regulation of cell-cell adhesion by Abi/Diaphanous complexes.	ABI1 ABI2	4.91e-06	3	45	2	19158278
Pubmed	Molecular screening of deafness in Algeria: high genetic heterogeneity involving DFNB1 and the Usher loci, DFNB2/USH1B, DFNB12/USH1D and DFNB23/USH1F.	PCDH15 MYO7A	4.91e-06	3	45	2	19375528
Pubmed	In search of a function for the E3B1/Abi2/Argbp1/NESH family (Review).	ABI1 ABI2	4.91e-06	3	45	2	12011975
Pubmed	Survey of the frequency of USH1 gene mutations in a cohort of Usher patients shows the importance of cadherin 23 and protocadherin 15 genes and establishes a detection rate of above 90%.	PCDH15 MYO7A	4.91e-06	3	45	2	16679490
Pubmed	Genetic analysis of Tunisian families with Usher syndrome type 1: toward improving early molecular diagnosis.	PCDH15 MYO7A	4.91e-06	3	45	2	27440999
Pubmed	Physical and functional interaction between protocadherin 15 and myosin VIIa in mechanosensory hair cells.	PCDH15 MYO7A	9.81e-06	4	45	2	16481439
Pubmed	Abl interactor 1 (Abi-1) wave-binding and SNARE domains regulate its nucleocytoplasmic shuttling, lamellipodium localization, and wave-1 levels.	ABI1 ABI2	9.81e-06	4	45	2	15143189
Pubmed	Usher syndromes due to MYO7A, PCDH15, USH2A or GPR98 mutations share retinal disease mechanism.	PCDH15 MYO7A	9.81e-06	4	45	2	18463160
Pubmed	Localization and phosphorylation of Abl-interactor proteins, Abi-1 and Abi-2, in the developing nervous system.	ABI1 ABI2	9.81e-06	4	45	2	10995551
Pubmed	Mechanotransduction is required for establishing and maintaining mature inner hair cells and regulating efferent innervation.	PCDH15 MYO7A	9.81e-06	4	45	2	30275467
Pubmed	Analysis of subcellular localization of Myo7a, Pcdh15 and Sans in Ush1c knockout mice.	PCDH15 MYO7A	9.81e-06	4	45	2	21156003
Pubmed	Role of the F-box protein Skp2 in cell proliferation in the developing auditory system in mice.	SKP2 MYO7A	9.81e-06	4	45	2	12692478
Pubmed	Degradation of Cdt1 during S phase is Skp2-independent and is required for efficient progression of mammalian cells through S phase.	CDT1 SKP2	9.81e-06	4	45	2	15855168
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SRGAP2 ATG9A STK40 ZNF585A DST KALRN MYO7A PHF12 INTS11	1.01e-05	1105	45	9	35748872
Pubmed	Interactions in the network of Usher syndrome type 1 proteins.	PCDH15 MYO7A	1.63e-05	5	45	2	15590703
Pubmed	Characterization of Usher syndrome type I gene mutations in an Usher syndrome patient population.	PCDH15 MYO7A	1.63e-05	5	45	2	15660226
Pubmed	ABI2-deficient mice exhibit defective cell migration, aberrant dendritic spine morphogenesis, and deficits in learning and memory.	ABI1 ABI2	1.63e-05	5	45	2	15572692
Pubmed	Usher I syndrome: unravelling the mechanisms that underlie the cohesion of the growing hair bundle in inner ear sensory cells.	PCDH15 MYO7A	1.63e-05	5	45	2	16219682
Pubmed	Abl-interactor-1 (Abi1) has a role in cardiovascular and placental development and is a binding partner of the alpha4 integrin.	ABI1 ABI2	1.63e-05	5	45	2	21173240
Pubmed	Digenic inheritance of deafness caused by 8J allele of myosin-VIIA and mutations in other Usher I genes.	PCDH15 MYO7A	1.63e-05	5	45	2	22381527
Pubmed	Mutations of the protocadherin gene PCDH15 cause Usher syndrome type 1F.	PCDH15 MYO7A	1.63e-05	5	45	2	11398101
Pubmed	Impact of the Usher syndrome on olfaction.	PCDH15 MYO7A	2.45e-05	6	45	2	26620972
Pubmed	The SCF(Skp2) ubiquitin ligase complex interacts with the human replication licensing factor Cdt1 and regulates Cdt1 degradation.	CDT1 SKP2	2.45e-05	6	45	2	12840033
Pubmed	Cyclin-dependent kinases phosphorylate human Cdt1 and induce its degradation.	CDT1 SKP2	2.45e-05	6	45	2	15004027
Pubmed	The ORC ubiquitin ligase OBI1 promotes DNA replication origin firing.	CDT1 SKP2 NFIL3	2.58e-05	44	45	3	31160578
Pubmed	Fat3 acts through independent cytoskeletal effectors to coordinate asymmetric cell behaviors during polarized circuit assembly.	ABI1 ABI2	3.42e-05	7	45	2	35108541
Pubmed	JNK1 phosphorylation of Cdt1 inhibits recruitment of HBO1 histone acetylase and blocks replication licensing in response to stress.	CDT1 SKP2	3.42e-05	7	45	2	21856198
Pubmed	DNA repair gene polymorphisms and risk of pancreatic cancer.	ATM POLB	3.42e-05	7	45	2	19147782
Pubmed	Skp2 E3 ligase integrates ATM activation and homologous recombination repair by ubiquitinating NBS1.	ATM SKP2	3.42e-05	7	45	2	22464731
Pubmed	Role of myosin VIIa and Rab27a in the motility and localization of RPE melanosomes.	PCDH15 MYO7A	3.42e-05	7	45	2	15572405
Pubmed	Usher Syndrome Type I	PCDH15 MYO7A	3.42e-05	7	45	2	20301442
Pubmed	Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding.	CDT1 SKP2	3.42e-05	7	45	2	14993212
Pubmed	Specific and ubiquitous expression of different Zn finger protein genes in the mouse.	ZNF585A ZNF585B	3.42e-05	7	45	2	3143103
Pubmed	Usher type 1G protein sans is a critical component of the tip-link complex, a structure controlling actin polymerization in stereocilia.	PCDH15 MYO7A	3.42e-05	7	45	2	21436032
Pubmed	Microarray-based mutation analysis of 183 Spanish families with Usher syndrome.	PCDH15 MYO7A	4.56e-05	8	45	2	19683999
Pubmed	Stereocilin connects outer hair cell stereocilia to one another and to the tectorial membrane.	PCDH15 MYO7A	4.56e-05	8	45	2	21165971
Pubmed	HIV-1 Vpr-induced apoptosis is cell cycle dependent and requires Bax but not ANT.	ATM DIABLO	4.56e-05	8	45	2	17140287
Pubmed	UMD-USHbases: a comprehensive set of databases to record and analyse pathogenic mutations and unclassified variants in seven Usher syndrome causing genes.	PCDH15 MYO7A	4.56e-05	8	45	2	18484607
Pubmed	Molecular basis of human Usher syndrome: deciphering the meshes of the Usher protein network provides insights into the pathomechanisms of the Usher disease.	PCDH15 MYO7A	4.56e-05	8	45	2	16545802
Pubmed	Structure and control of the actin regulatory WAVE complex.	ABI1 ABI2	4.56e-05	8	45	2	21107423
Pubmed	The histone demethylase LSD1/KDM1A promotes the DNA damage response.	CDT1 ATM	5.86e-05	9	45	2	24217620
Pubmed	Tonotopic gradient in the developmental acquisition of sensory transduction in outer hair cells of the mouse cochlea.	PCDH15 MYO7A	5.86e-05	9	45	2	19339464
Pubmed	A core cochlear phenotype in USH1 mouse mutants implicates fibrous links of the hair bundle in its cohesion, orientation and differential growth.	PCDH15 MYO7A	5.86e-05	9	45	2	18339676
Pubmed	Massively parallel DNA sequencing facilitates diagnosis of patients with Usher syndrome type 1.	PCDH15 MYO7A	7.32e-05	10	45	2	24618850
Pubmed	Usher protein functions in hair cells and photoreceptors.	PCDH15 MYO7A	7.32e-05	10	45	2	24239741
Pubmed	NESH (Abi-3) is present in the Abi/WAVE complex but does not promote c-Abl-mediated phosphorylation.	ABI1 ABI2	7.32e-05	10	45	2	17101133
Pubmed	Otogelin, otogelin-like, and stereocilin form links connecting outer hair cell stereocilia to each other and the tectorial membrane.	PCDH15 MYO7A	8.94e-05	11	45	2	31776257
Pubmed	CIB2 interacts with TMC1 and TMC2 and is essential for mechanotransduction in auditory hair cells.	PCDH15 MYO7A	1.07e-04	12	45	2	28663585
Pubmed	DDB1 is essential for genomic stability in developing epidermis.	CDT1 ATM	1.27e-04	13	45	2	17301228
Pubmed	Class III myosins shape the auditory hair bundles by limiting microvilli and stereocilia growth.	PCDH15 MYO7A	1.47e-04	14	45	2	26754646
Pubmed	Parkin mediates the ubiquitination of VPS35 and modulates retromer-dependent endosomal sorting.	ATG9A GOLGA4	1.70e-04	15	45	2	29893854
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SRGAP2 ABI1 DST KALRN ABI2 SRGAP3 GOLGA4	2.21e-04	963	45	7	28671696
Pubmed	Gene Expression by Mouse Inner Ear Hair Cells during Development.	PCDH15 MYO7A	2.76e-04	19	45	2	25904789
Pubmed	Identification of novel human Cdt1-binding proteins by a proteomics approach: proteolytic regulation by APC/CCdh1.	CDT1 SKP2	3.06e-04	20	45	2	18162579
Pubmed	A quantitative survey of gravity receptor function in mutant mouse strains.	PCDH15 MYO7A	3.06e-04	20	45	2	16235133
Pubmed	The LIFEdb database in 2006.	ATG9A STK40 SUN2 ANKRD20A1 VCPIP1 INTS11	3.16e-04	720	45	6	16381901
Pubmed	From ORFeome to biology: a functional genomics pipeline.	ATG9A STK40 SUN2 ANKRD20A1 VCPIP1 INTS11	3.21e-04	722	45	6	15489336
Pubmed	Human Cytomegalovirus UL135 Interacts with Host Adaptor Proteins To Regulate Epidermal Growth Factor Receptor and Reactivation from Latency.	ABI1 ABI2	3.72e-04	22	45	2	30089695
Pubmed	Crosstalk between lysine methylation and phosphorylation of ATG16L1 dictates the apoptosis of hypoxia/reoxygenation-induced cardiomyocytes.	ATM TNKS2	3.72e-04	22	45	2	29634390
Pubmed	Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.	ATG9A STK40 SUN2 ANKRD20A1 VCPIP1 INTS11	3.92e-04	750	45	6	11230166
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	ABI1 DST TNKS2 KALRN NFIL3	4.45e-04	497	45	5	23414517
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	TRAPPC10 SRGAP2 HTRA1 ABI1 DST KALRN MYO7A SRGAP3	4.46e-04	1431	45	8	37142655
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	TRAPPC10 CDT1 ATM PHF12 GOLGA4 VCPIP1	4.63e-04	774	45	6	15302935
Pubmed	BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.	TRAPPC10 ATG9A DST GOLGA4	5.05e-04	285	45	4	34369648
Pubmed	HENA, heterogeneous network-based data set for Alzheimer's disease.	DST TNKS2 GOLGA4	5.11e-04	120	45	3	31413325
Pubmed	Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication.	CDT1 SKP2	5.22e-04	26	45	2	11931757
Pubmed	PTEN dephosphorylates Abi1 to promote epithelial morphogenesis.	ABI1 ABI2	5.22e-04	26	45	2	32673396
Pubmed	DNA cloning using in vitro site-specific recombination.	ATG9A STK40 SUN2 ANKRD20A1 VCPIP1 INTS11	5.30e-04	794	45	6	11076863
Pubmed	Atm deficiency in the DNA polymerase β null cerebellum results in cerebellar ataxia and Itpr1 reduction associated with alteration of cytosine methylation.	ATM POLB	6.50e-04	29	45	2	32123907
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	ABI1 STK40 SKP2 ABI2 NFIL3 ANKRD20A1	7.90e-04	857	45	6	25609649
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	SRGAP2 ABI1 DST SRGAP1 GOLGA4 VCPIP1	8.09e-04	861	45	6	36931259
Pubmed	The addition of 5'-coding information to a 3'-directed cDNA library improves analysis of gene expression.	NFIL3 ADGRG6	1.06e-03	37	45	2	8076819
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ODF2L SRGAP2 ATM DST TNKS2 KALRN VCPIP1	1.23e-03	1285	45	7	35914814
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	DST NFIL3 POLB PHF12 SUN2 VCPIP1 INTS11	1.28e-03	1294	45	7	30804502
Interaction	ANKRD20A4P interactions	ANKRD20A2P ANKRD20A4P ANKRD20A1	2.07e-07	6	45	3	int:ANKRD20A4P
Interaction	ANKRD20A2P interactions	ANKRD20A2P ANKRD20A4P ANKRD20A1	3.62e-07	7	45	3	int:ANKRD20A2P
Interaction	DISC1 interactions	SRGAP2 ATG9A DST TNKS2 KALRN SKP2 ABI2 SRGAP3 SUN2	3.71e-07	429	45	9	int:DISC1
Interaction	ANKRD20A1 interactions	ANKRD20A2P ANKRD20A4P ANKRD20A1	1.70e-06	11	45	3	int:ANKRD20A1
Interaction	RAPH1 interactions	ABI1 ABI2 SRGAP3 SRGAP1	1.25e-05	64	45	4	int:RAPH1
Interaction	PCDH15 interactions	PCDH15 MYO7A	7.27e-05	6	45	2	int:PCDH15
Interaction	FASLG interactions	SRGAP2 KALRN SRGAP3 SRGAP1	8.80e-05	105	45	4	int:FASLG
Interaction	YWHAH interactions	TRAPPC10 SRGAP2 ABI1 ATG9A DST ABI2 DIABLO SRGAP1 GOLGA4 VCPIP1	1.27e-04	1102	45	10	int:YWHAH
Cytoband	9p12	ANKRD20A2P ANKRD20A3P	3.75e-04	29	45	2	9p12
GeneFamily	Rho GTPase activating proteins\|F-BAR domain containing	SRGAP2 SRGAP3 SRGAP1	7.90e-06	23	31	3	1288
GeneFamily	Ankyrin repeat domain containing	ANKRD20A2P ANKRD20A3P TNKS2 ANKRD20A4P ANKRD20A1	5.27e-05	242	31	5	403
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	SRGAP2 SRGAP3 SRGAP1	8.47e-05	50	31	3	721
GeneFamily	Cadherin related	PCDH15 CLSTN2	3.81e-04	17	31	2	24
GeneFamily	Actins\|Deafness associated genes	PCDH15 MYO7A DIABLO	9.41e-04	113	31	3	1152
ToppCell	COPD-Myeloid-cDC1\|World / Disease state, Lineage and Cell class	ANKRD20A2P ANKRD20A3P ANKRD20A8P DST ANKRD20A4P ANKRD20A1	3.08e-08	184	45	6	42d7ce104cd7bcb83fbbbd0e7d3267ad07edfa94
ToppCell	COPD-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1 ADGRG6	3.84e-08	191	45	6	3480e6d27dd4291765bbbb2acdb6a2e4f02c8085
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_C\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ANKRD20A2P ATM ANKRD20A4P KALRN ANKRD20A1	7.85e-07	170	45	5	81341bf4fe090af70b2091b6b2579ed08d76e22d
ToppCell	Control-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	1.16e-06	184	45	5	c6affa0b12510363258f65e46bf2d47bf4a8e75f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2 HTRA1 DST PRDM5 SRGAP1	1.19e-06	185	45	5	9197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2 HTRA1 DST PRDM5 SRGAP1	1.19e-06	185	45	5	ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCell	IPF-Myeloid-cDC1\|World / Disease state, Lineage and Cell class	ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	1.22e-06	186	45	5	962c2dada19185628ead77c32fcb07fa95114247
ToppCell	Control-Myeloid-cDC1\|Control / Disease state, Lineage and Cell class	ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	1.22e-06	186	45	5	b05c394aa3573ba855abc3066739ca193883b0c3
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_C\|390C / Donor, Lineage, Cell class and subclass (all cells)	ANKRD20A2P ATM ANKRD20A4P SUN2 ANKRD20A1	1.26e-06	187	45	5	1e8651e6c547384ace5a66b96c6b24a7f390a7ee
ToppCell	IPF-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	1.29e-06	188	45	5	47bb6caf84f70a1cda7d09803afdfd5182772e66
ToppCell	IPF-Myeloid-cDC1\|IPF / Disease state, Lineage and Cell class	ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	1.29e-06	188	45	5	2331a2bae1383820d598e93aa86c75b101069bac
ToppCell	COPD-Myeloid-cDC1\|COPD / Disease state, Lineage and Cell class	ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	1.43e-06	192	45	5	bd3d00b094d92463b06023361a71240851a542b8
ToppCell	mLN-(5)_Dendritic_cell-(53)_Lymphoid_DC\|mLN / shred on region, Cell_type, and subtype	ANKRD20A2P ANKRD20A3P ANKRD20A4P SRGAP1 ANKRD20A1	1.66e-06	198	45	5	da84c76afe835aeee39da04b63c03549218b5d91
ToppCell	mLN-Dendritic_cell-Lymphoid_DC\|mLN / Region, Cell class and subclass	ANKRD20A2P ANKRD20A3P ANKRD20A4P SRGAP1 ANKRD20A1	1.66e-06	198	45	5	3965a9f1e8a51a196e5349aaca5fa5ed1cd8ee92
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-STK32A\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PCDH15 HTRA1 PRKX SRGAP1 ADGRG6	1.75e-06	200	45	5	8d51b4f7b7002ee51401ebe5eaca1e8f04bfadd5
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-STK32A-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PCDH15 HTRA1 PRKX SRGAP1 ADGRG6	1.75e-06	200	45	5	6a44439e4a7ce3627271375b04cfcfb9467218f4
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-STK32A--L4-5\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PCDH15 HTRA1 PRKX SRGAP1 ADGRG6	1.75e-06	200	45	5	cb1f4b0d66da5b0466ff17b29e7034d451d93e4f
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DST DNAH10 SRGAP3 ADGRG6	1.72e-05	153	45	4	91e9d70a5d3f6fd68c284ed0cc113f03d7d1e10b
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DST DNAH10 SRGAP3 ADGRG6	1.72e-05	153	45	4	f17f62646633cf95c810dcd5328978058741b276
ToppCell	5'-Adult-Appendix-Hematopoietic-T_cells-gdT\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ODF2L ZNF782 ANKRD20A4P SRGAP3	1.76e-05	154	45	4	d2aa24c593a1c0c6f186b74a18438b64b4e59701
ToppCell	Control-B_naive-12\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	MPP1 ZNF585A DST SKP2	1.90e-05	157	45	4	4803f601c1ba43260aa09172acc7964aac2c8ccf
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_macrophage-microglial_cell\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SRGAP2 HTRA1 DST SRGAP1	1.90e-05	157	45	4	d4908cafd8870c1c225817f589ea2bce116ac7ab
ToppCell	normal_Lymph_Node-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	DST DNAH10 CENPC POLB	2.84e-05	174	45	4	2274648b80dd74f3c948a779bba3391095964c34
ToppCell	10x5'-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages\|lymph-node_spleen / Manually curated celltypes from each tissue	MPP1 DST SRGAP1 ADGRG6	3.25e-05	180	45	4	7be7d7a6906fff6dbdecd9cb013d855aba4eda2a
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2 HTRA1 DST SRGAP1	3.32e-05	181	45	4	5bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2 HTRA1 DST SRGAP1	3.32e-05	181	45	4	8e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCell	wk_15-18-Hematologic-Meg-ery-Definitive_erythroblast\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	MPP1 ATG9A ANKRD20A4P ANKRD20A1	3.39e-05	182	45	4	93841f730ca1a735eaaf5f2ccbe5c45ab0e029d1
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SRGAP2 HTRA1 NFIL3 GOLGA4	3.46e-05	183	45	4	614a1c08cf6d01a4f1ed2fb816cd1a6e0c3207ce
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2 HTRA1 PRDM5 SRGAP1	3.46e-05	183	45	4	eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDH15 DRP2 DNAH10 KALRN	3.54e-05	184	45	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDH15 DRP2 DNAH10 KALRN	3.54e-05	184	45	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDH15 DRP2 DNAH10 KALRN	3.54e-05	184	45	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_11\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ANKRD20A3P DST ANKRD20A1 ADGRG6	3.54e-05	184	45	4	667846c422cfa27e949a24844a305df859cb6760
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-5_PVALB_TRIM67\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCDH15 HTRA1 PRKX ADGRG6	3.54e-05	184	45	4	7f6c8912677764d438ab0555faca344d74c2f483
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2 HTRA1 DST SRGAP1	3.61e-05	185	45	4	b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCell	Control-Myeloid-cDC1\|World / Disease state, Lineage and Cell class	ANKRD20A2P ANKRD20A3P ANKRD20A4P ANKRD20A1	3.69e-05	186	45	4	3de803dee3ef10eb85a2b47d3f93385214e5b0ff
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_dendritic-CD141-positive_myeloid_dendritic_cell\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ANKRD20A3P DST SRGAP1 ADGRG6	3.85e-05	188	45	4	78e79b8e298aa77c8c01320bab4fb1a00f11a772
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MPP1 SRGAP2 MYO7A SRGAP1	4.01e-05	190	45	4	2d54fca50593fbd11fe13fc2bfaf937a05db776d
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2 HTRA1 DST SRGAP1	4.26e-05	193	45	4	3eaa0461618582a1754400624350d269d24e750a
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PCDH15 DST KALRN SRGAP1	4.35e-05	194	45	4	011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DST KALRN SRGAP3 ADGRG6	4.35e-05	194	45	4	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HTRA1 DST SRGAP1 ADGRG6	4.35e-05	194	45	4	43eb677a76634bb9a48a40e0d607c4936ae64bcc
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	DST KALRN SRGAP3 ADGRG6	4.44e-05	195	45	4	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	tumor_Lung-T/NK_cells-Exhausted_Tfh\|T/NK_cells / Location, Cell class and cell subclass	HTRA1 MYO7A SRGAP3 GOLGA4	4.53e-05	196	45	4	5a0b5aeff7e535781ea2a4c85799bb468afcb6f8
ToppCell	COPD-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	PCDH15 ANKRD20A2P ANKRD20A3P ANKRD20A4P	4.62e-05	197	45	4	30dbc05ea66892d2e18ff375ffa86d1db7bc4083
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DST KALRN SRGAP3 ADGRG6	4.62e-05	197	45	4	31a1852911bda38543916585fda34255fd62a134
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intermediate\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MPP1 SRGAP2 NFIL3 SRGAP1	4.62e-05	197	45	4	e2983ae16c72371fbf0e5c123de9f4d900724e5e
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ODF2L CLSTN2 DNAH10 LMLN	4.62e-05	197	45	4	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intravascular\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MPP1 SRGAP2 MYO7A SRGAP1	4.71e-05	198	45	4	c7dbf24caae5c4ef285845d13055de9e07281bb3
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ANKRD20A2P ANKRD20A3P ANKRD20A4P VCPIP1	4.71e-05	198	45	4	fa5c15a656d4132950092919600e270f1fd79abf
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	ODF2L MAB21L3 GOLGA4 LMLN	4.71e-05	198	45	4	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	(10)_Ciliated-(2)_GFP_FOXI1\|(10)_Ciliated / shred by cell type by condition	ODF2L MAB21L3 GOLGA4 LMLN	4.80e-05	199	45	4	61b1ed2db71b96157b92b7535d1955a4033098da
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Neuron\|2m / Sample Type, Dataset, Time_group, and Cell type.	KALRN PRKX SRGAP3 SUN2	4.89e-05	200	45	4	a581f1704a87b0390e1e2ff85053367d85247755
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Intermediate\|2m / Sample Type, Dataset, Time_group, and Cell type.	DST ABI2 SRGAP3 SRGAP1	4.89e-05	200	45	4	2a635694844ddabcd98462c5636a6f41a3f08a46
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Neuron\|6m / Sample Type, Dataset, Time_group, and Cell type.	KALRN PRKX SRGAP3 SUN2	4.89e-05	200	45	4	b5019b9d48f32cffd4645a5c0f3e0ac504ea8019
ToppCell	mild-gd_T\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ODF2L ATM CENPC GOLGA4	4.89e-05	200	45	4	109f673a4967ffa52270a0b4f818b3461288db44
ToppCell	(53)_Lymphoid_DC\|World / shred on Cell_type and subtype	ANKRD20A2P ANKRD20A3P SRGAP1 ANKRD20A1	5.70e-05	208	45	4	30212cfacad94a7cc562a69efa73a31259851515
ToppCell	AT2_cells-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	ANKRD20A2P ANKRD20A3P ANKRD20A4P	3.13e-04	131	45	3	ff4e618bd944f852bbd34438f740187aca82460f
ToppCell	TCGA-Peripheral_Nervous_System-Primary_Tumor-Paraganglioma-Paraganglioma-3\|TCGA-Peripheral_Nervous_System / Sample_Type by Project: Shred V9	ATM PRDM5 SKP2	3.42e-04	135	45	3	ac20133d4a36f48338b45bffb13e842cb66f83ad
ToppCell	10x5'-Lung-Myeloid_Mac-Intestinal_macrophages\|Lung / Manually curated celltypes from each tissue	HTRA1 SRGAP1 ADGRG6	3.88e-04	141	45	3	7671d300b1722711fd2d8034b96a3aa7e3ccb560
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ATG9A ANKRD20A8P CENPC	4.56e-04	149	45	3	54c9c6282f5f5de43dfaf2972fab3e3dcf9838a3
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ATG9A ANKRD20A8P CENPC	4.56e-04	149	45	3	14d2e8cab97108d8fa94e540c1957b73ed32dc73
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_dendritic-myeloid_dendritic_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SRGAP2 ANKRD20A3P ANKRD20A4P	4.56e-04	149	45	3	71d72a6e7b128ee96161e08f6a0d77be925e73a1
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1\|343B / Donor, Lineage, Cell class and subclass (all cells)	ATM ZNF782 POLB	4.56e-04	149	45	3	2a7f71da51c85e04de2123164914122480e60d66
ToppCell	390C-Fibroblasts-Fibroblast-G-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	PCDH15 DST LMLN	4.83e-04	152	45	3	ebce79e106bf1d84241f8dd3496ff1771f9666be
ToppCell	390C-Fibroblasts-Fibroblast-G\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	PCDH15 DST LMLN	4.83e-04	152	45	3	4a749d1b6d35fd55a8c42d7bd04b6ff5b11ce781
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PCDH15 MAB21L3 SRGAP3	4.93e-04	153	45	3	3240d4d690335ba22317b1f3d33f9ea069e93838
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PCDH15 MAB21L3 SRGAP3	4.93e-04	153	45	3	edf5d026e8e4c685b7c369d70894741bb2cd568e
ToppCell	10x5'-Liver-Myeloid_Mac-Intestinal_macrophages\|Liver / Manually curated celltypes from each tissue	DST SRGAP3 ADGRG6	5.21e-04	156	45	3	9a897fc79c4fae94c5f2e9012d65297f9225e5e3
ToppCell	severe_COVID-19-cDC\|severe_COVID-19 / disease group, cell group and cell class (v2)	DST ANKRD20A1 ADGRG6	5.31e-04	157	45	3	ec1978e07e2214048d015d8bb793c1d9991f6e37
ToppCell	Control-B_naive-12\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	MPP1 ZNF585A DST	5.41e-04	158	45	3	41318f864770370ce77ed3fa4a84f76c0c22c482
ToppCell	normal_Pleural_Fluid-T/NK_cells-CD4+_Th\|normal_Pleural_Fluid / Location, Cell class and cell subclass	HTRA1 ANKRD20A4P MYO7A	5.51e-04	159	45	3	ebd840ac2b07e62086ee7b5bb01c21804a0fdc7b
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLSTN2 ABI2 ADGRG6	5.72e-04	161	45	3	82ed45f144a07856fe92d37426c5f92e259a03a9
ToppCell	356C-Lymphocytic-ILC-ILC-3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	HTRA1 ATG9A SRGAP3	5.92e-04	163	45	3	2dbdcbc4c187aad3db837d191cc78662a75dd0b5
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SRGAP2 HTRA1 GOLGA4	5.92e-04	163	45	3	a6e272e043859858084b8d4d96fa4ff9e6eca454
ToppCell	normal_Pleural_Fluid-T/NK_cells-CD4+_Th\|T/NK_cells / Location, Cell class and cell subclass	HTRA1 ANKRD20A4P MYO7A	6.03e-04	164	45	3	334f376350c9cf92611d0f75b2e18a102f4c116a
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDT1 ZNF585A DNAH10	6.14e-04	165	45	3	1703d3eb644b3c743ad3c5532b1d29ea010c79c8
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_dendritic\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ANKRD20A3P ANKRD20A4P SRGAP1	6.25e-04	166	45	3	479391aa6c09aa070b716128ab51b8fec0aea22d
ToppCell	droplet-Heart-nan-18m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATM DRP2 PRDM5	6.25e-04	166	45	3	9adceb746e67e955fd8b3e0984f4eed44b64a270
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SRGAP2 MAB21L3 ATM	6.36e-04	167	45	3	942134bbabe9972fae80cbc4ed4e94da52f55dc3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2 HTRA1 DST	6.47e-04	168	45	3	315ca578c945aeeb77acda2727f3e6db8b43f43e
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ABI1 KALRN ABI2	6.47e-04	168	45	3	6db453cbbbaf4144a86fadcfa5805d33396713b5
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2 HTRA1 DST	6.47e-04	168	45	3	e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-Exhausted_Tfh\|T/NK_cells / Location, Cell class and cell subclass	SRGAP3 NFIL3 SRGAP1	6.58e-04	169	45	3	625788d86f0ceebcf2653a251db1f1a9f9746d29
ToppCell	Adult-Endothelial-endothelial_cell_of_vein-D175\|Adult / Lineage, Cell type, age group and donor	ANKRD20A4P KALRN ADGRG6	6.58e-04	169	45	3	e1f0298236e4a1c59077c14f0dd29a78fac12648
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH10 SRGAP3 LMLN	6.58e-04	169	45	3	fba841664939c771881ba97f14ef1df6635c04ff
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SRGAP2 NFIL3 GOLGA4	6.58e-04	169	45	3	0867528101767fc65e93b3561480bf830c50368d
ToppCell	healthy_donor-Myeloid-Monocytic-Developing_Neutrophil\|healthy_donor / Disease condition, Lineage, Cell class and subclass	ANKRD20A4P DNAH10 ADGRG6	6.69e-04	170	45	3	cfd7f29805b7c51666b0eaf269c36c96b8765a1a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2 HTRA1 DST	6.92e-04	172	45	3	6c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRAPPC10 NFIL3 LMLN	6.92e-04	172	45	3	ebeda7ef181cac0109be750a98e7589c615d2724
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2 HTRA1 SRGAP1	6.92e-04	172	45	3	381ae1c3c07d0a424f43455ec571653b192a946a
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLSTN2 CWH43 ADGRG6	6.92e-04	172	45	3	03a0aff6b7971093a4347b5ed12546d78374c56f
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLSTN2 CDT1 KALRN	7.04e-04	173	45	3	12f779b8dce79431b2d1002ba524dd3f9566aeb0
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_12\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CDT1 DST ADGRG6	7.04e-04	173	45	3	9c7386bf0a899882c733f0b4921a96afde032a7d
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_12\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CDT1 DST ADGRG6	7.04e-04	173	45	3	a55f310c533432e9e26e400026a5b47245152976
ToppCell	mild_COVID-19_(asymptomatic)-cDC\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	ANKRD20A3P DST ADGRG6	7.04e-04	173	45	3	71dc0051c87b84e3cf13cde8858166f2a474b5dc
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_E\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ATG9A KALRN SRGAP3	7.16e-04	174	45	3	a1f745962a104c6f4b86b7e482da8755384c773a
ToppCell	Basal_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	ANKRD20A2P ANKRD20A3P ANKRD20A4P	7.16e-04	174	45	3	a0060be3940043015dcc49a5157de5541aed24a1
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRDM5 KALRN SRGAP3	7.28e-04	175	45	3	9a96a946db731ba24c9be34bedebf1f4a1372b9e
ToppCell	PBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_CD56bright\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ATM DST SRGAP3	7.28e-04	175	45	3	e219b61d6bc078d44ea7d06191d3462654d857a1
Disease	Usher Syndrome	PCDH15 MYO7A	1.13e-05	4	41	2	C0271097
Disease	Usher Syndrome, Type II	PCDH15 MYO7A	1.88e-05	5	41	2	C1568249
Disease	Usher syndrome, type 1A	PCDH15 MYO7A	1.88e-05	5	41	2	C2931205
Disease	USHER SYNDROME, TYPE IB (disorder)	PCDH15 MYO7A	1.88e-05	5	41	2	C1848638
Disease	USHER SYNDROME, TYPE IA, FORMERLY	PCDH15 MYO7A	1.88e-05	5	41	2	C1848639
Disease	USHER SYNDROME, TYPE I, FRENCH VARIETY, FORMERLY	PCDH15 MYO7A	1.88e-05	5	41	2	C1848640
Disease	Usher syndrome type 1	PCDH15 MYO7A	1.88e-05	5	41	2	cv:C1568247
Disease	Usher Syndrome, Type I	PCDH15 MYO7A	2.82e-05	6	41	2	C1568247
Disease	Hereditary retinal dystrophy	PCDH15 MYO7A	3.94e-05	7	41	2	C0154860
Disease	Usher Syndrome, Type III	PCDH15 MYO7A	3.94e-05	7	41	2	C1568248
Disease	Usher syndrome	PCDH15 MYO7A	3.94e-05	7	41	2	cv:C0271097
Disease	Nonsyndromic genetic hearing loss	PCDH15 MYO7A DIABLO	1.63e-04	76	41	3	cv:C5680182
Disease	Nonsyndromic Deafness	PCDH15 MYO7A DIABLO	1.97e-04	81	41	3	C3711374
Disease	white matter microstructure measurement	SRGAP2 ABI2 SRGAP3 SUN2 ADGRG6	1.99e-04	390	41	5	EFO_0005674
Disease	idiopathic scoliosis (implicated_via_orthology)	DNAH10 ADGRG6	2.23e-04	16	41	2	DOID:0060250 (implicated_via_orthology)
Disease	hearing impairment	PCDH15 MYO7A DIABLO	3.46e-04	98	41	3	C1384666
Disease	hippocampus volume change measurement, age at assessment	PCDH15 SUN2	7.47e-04	29	41	2	EFO_0008007, EFO_0021492
Disease	Autosomal dominant nonsyndromic hearing loss	MYO7A DIABLO	7.47e-04	29	41	2	cv:C5779548
Disease	cholesteryl ester 22:6 measurement	SRGAP2 SRGAP3	9.10e-04	32	41	2	EFO_0010350
Disease	cysteine-rich with EGF-like domain protein 1 measurement	SRGAP2 SRGAP3	9.10e-04	32	41	2	EFO_0021870
Disease	Hereditary hearing loss and deafness	PCDH15 MYO7A DIABLO	1.10e-03	146	41	3	cv:C0236038
Disease	skin microbiome measurement	SRGAP2 SRGAP3	1.35e-03	39	41	2	EFO_0801228
Disease	lung non-small cell carcinoma (is_marker_for)	HTRA1 ATM DIABLO	1.68e-03	169	41	3	DOID:3908 (is_marker_for)
Disease	Medulloblastoma	ATM SKP2	2.21e-03	50	41	2	C0025149
Disease	Nonsyndromic Hearing Loss and Deafness, Autosomal Recessive	PCDH15 MYO7A	2.30e-03	51	41	2	cv:CN043650
Disease	Chronic Lymphocytic Leukemia	ATM POLB	2.67e-03	55	41	2	C0023434

Protein segments in the cluster

Peptide	Gene	Start	Entry
VHQKEDHKEIVTNIQ	ANKRD20A1	751	Q5TYW2
VHQKEDHKEIVTNIQ	ANKRD20A8P	751	Q5CZ79
VHQKEDHKEIVTNIQ	ANKRD20A4P	751	Q4UJ75
VQIKIKHTRTQEVHH	ADGRG6	786	Q86SQ4
QIFSQKLVEHVKEHH	CDT1	296	Q9H211
NHISQTVDIHKEKVA	ABI1	91	Q8IZP0
HIQLVKLQVEEVHQL	DIABLO	186	Q9NR28
SHKAVVHIQVKDVNE	CLSTN2	141	Q9H4D0
NHISQTVDIHKEKVA	ABI2	91	Q9NYB9
SVKVVHERLQIQIHK	ODF2L	181	Q9ULJ1
FKRKDTLNVHVQVVH	PRDM5	441	Q9NQX1
TLNVHVQVVHERHKK	PRDM5	446	Q9NQX1
VHQKEDHKEIVTNIQ	ANKRD20A2P	751	Q5SQ80
KKVVAVHLHQTVQVD	INTS11	131	Q5TA45
HHQQQVDSIIKEHEV	GOLGA4	731	Q13439
QHEKIISQHQAVIIA	DST	3856	Q03001
DTEVINKVHLKANHV	LMLN	71	Q96KR4
KHVHATVVKVPEVNS	NFIL3	306	Q16649
SKAVHQVLDVVHEVL	KALRN	501	O60229
QAVEEVQKVVHHLTT	MAB21L3	26	Q8N8X9
IHSIVVQVQCINKKV	PCDH15	111	Q96QU1
VCKTILNHVLHVVKN	ATM	986	Q13315
VHQKEDHKEIVTNIQ	ANKRD20A3P	751	Q5VUR7
VTNAHVVTNKHRVKV	HTRA1	216	Q92743
VQAHEVHQKILATDV	CENPC	111	Q03188
RIVQTQKEHQICIHK	ATG9A	186	Q7Z3C6
TKFETVHQIHKQNKI	MPP1	361	Q00013
VHQIHKQNKIAILDI	MPP1	366	Q00013
IENVVKHVVLVHQSV	DNAH10	2986	Q8IVF4
LHQVVEQLQKVHFIT	POLB	211	P06746
HRVTIAEQVKHQTKC	DRP2	596	Q13474
QKVVIDHREVSEKIH	CWH43	656	Q9H720
VVRVVEALHQKNIVH	STK40	181	Q8N2I9
QAHVNEIIKTIIIHH	SRGAP1	676	Q7Z6B7
SQHVVKVDFLNRIHK	PHF12	346	Q96QT6
EKHVQVAVAHVSETI	SKP2	271	Q13309
IGVTEEQVHHIVKQA	SUN2	521	Q9UH99
QAHINEVIKTIIIHH	SRGAP3	676	O43295
QAHVNELIKTIIIQH	SRGAP2	661	O75044
QKSILIVHQKIHTGE	ZNF585B	561	Q52M93
EILVQKVVHTILHQT	VCPIP1	641	Q96JH7
IRLKQEQHVHNEKSV	PRKX	86	P51817
AHNDVVEVVVKHEAK	TNKS2	411	Q9H2K2
QKSILIVHQKIHTGE	ZNF585A	561	Q6P3V2
LHHKEEVIQHQTIQT	ZNF782	196	Q6ZMW2
HVEQIVVNVHFSIEK	TRAPPC10	621	P48553
EVEAIQHKTTQIFHK	MYO7A	1891	Q13402