Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	D-ribulose-phosphate 3-epimerase activity	RPEL1 RPE	5.76e-05	2	152	2	GO:0004750
GeneOntologyMolecularFunction	vinculin binding	DLC1 DMD UTRN	1.17e-04	13	152	3	GO:0017166
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH2 DNAH17 DNAH11	3.24e-04	18	152	3	GO:0008569
GeneOntologyMolecularFunction	lamin binding	PKP1 DMD TOR1AIP1	3.83e-04	19	152	3	GO:0005521
Domain	Ribul_P_3_epim	RPEL1 RPE	6.58e-05	2	152	2	PF00834
Domain	Dystrophin	DMD UTRN	6.58e-05	2	152	2	IPR016344
Domain	RIBUL_P_3_EPIMER_1	RPEL1 RPE	6.58e-05	2	152	2	PS01085
Domain	Ribul_P_3_epim	RPEL1 RPE	6.58e-05	2	152	2	IPR026019
Domain	Ribul_P_3_epim-like	RPEL1 RPE	6.58e-05	2	152	2	IPR000056
Domain	RibuloseP-bd_barrel	RPEL1 RPE	1.96e-04	3	152	2	IPR011060
Domain	Laminin_N	LAMA5 LAMB3 USH2A	2.74e-04	16	152	3	IPR008211
Domain	LamNT	LAMA5 LAMB3 USH2A	2.74e-04	16	152	3	SM00136
Domain	LAMININ_NTER	LAMA5 LAMB3 USH2A	2.74e-04	16	152	3	PS51117
Domain	Laminin_N	LAMA5 LAMB3 USH2A	2.74e-04	16	152	3	PF00055
Domain	PBC	PBX2 PBX3	3.91e-04	4	152	2	PF03792
Domain	PBX	PBX2 PBX3	3.91e-04	4	152	2	IPR005542
Domain	ARM-type_fold	DOCK11 PKP4 INTS1 USP24 HSF2BP MEI1 ELMO2 PKP1 ATM SYMPK	4.68e-04	339	152	10	IPR016024
Domain	WW	WWC2 DMD UTRN WWC1	5.73e-04	47	152	4	PF00397
Domain	WW	WWC2 DMD UTRN WWC1	6.21e-04	48	152	4	SM00456
Domain	PKNOX/Meis_N	PKNOX2 PKNOX1	6.47e-04	5	152	2	IPR032453
Domain	Meis_PKNOX_N	PKNOX2 PKNOX1	6.47e-04	5	152	2	PF16493
Domain	Rho_GTPase_activation_prot	STARD13 GAPVD1 DLC1 RASAL1 ARAP1	7.61e-04	88	152	5	IPR008936
Domain	WW_DOMAIN_1	WWC2 DMD UTRN WWC1	7.83e-04	51	152	4	PS01159
Domain	WW_DOMAIN_2	WWC2 DMD UTRN WWC1	7.83e-04	51	152	4	PS50020
Domain	WW_dom	WWC2 DMD UTRN WWC1	8.43e-04	52	152	4	IPR001202
Domain	EF-hand_dom_typ1	DMD UTRN	9.66e-04	6	152	2	IPR015153
Domain	EF-hand_dom_typ2	DMD UTRN	9.66e-04	6	152	2	IPR015154
Domain	EF-hand_2	DMD UTRN	9.66e-04	6	152	2	PF09068
Domain	EF-hand_3	DMD UTRN	9.66e-04	6	152	2	PF09069
Domain	Kelch	KBTBD6 KBTBD7 KLHL29 KBTBD12	1.27e-03	58	152	4	SM00612
Domain	Prot-tyrosine_phosphatase-like	PTPN22 PTPRU MTMR10 PTPRD MTMR3	1.29e-03	99	152	5	IPR029021
Domain	Plakophilin/d_Catenin	PKP4 PKP1	1.35e-03	7	152	2	IPR028435
Domain	PTPc_motif	PTPN22 PTPRU PTPRD MTMR3	1.36e-03	59	152	4	SM00404
Domain	Tyr_Pase_cat	PTPN22 PTPRU PTPRD MTMR3	1.36e-03	59	152	4	IPR003595
Domain	BACK	KBTBD6 KBTBD7 KLHL29 KBTBD12	1.44e-03	60	152	4	SM00875
Domain	BACK	KBTBD6 KBTBD7 KLHL29 KBTBD12	1.54e-03	61	152	4	IPR011705
Domain	BACK	KBTBD6 KBTBD7 KLHL29 KBTBD12	1.54e-03	61	152	4	PF07707
Domain	DHC_N1	DNAH2 DNAH11	1.78e-03	8	152	2	PF08385
Domain	Vps4_C	VPS4A VCP	1.78e-03	8	152	2	IPR015415
Domain	Vps4_C	VPS4A VCP	1.78e-03	8	152	2	PF09336
Domain	INT_SG_DDX_CT_C	INTS6L SAGE1	1.78e-03	8	152	2	PF15300
Domain	INT_SG_DDX_CT_C	INTS6L SAGE1	1.78e-03	8	152	2	IPR029307
Domain	Dynein_heavy_dom-1	DNAH2 DNAH11	1.78e-03	8	152	2	IPR013594
Domain	EGF_LAM_2	LAMA5 LAMB3 USH2A	1.83e-03	30	152	3	PS50027
Domain	EGF_LAM_1	LAMA5 LAMB3 USH2A	1.83e-03	30	152	3	PS01248
Domain	ConA-like_dom	LAMA5 TRIM39 PTPRU ITGB4 MEP1B ADGRD2 USH2A	2.13e-03	219	152	7	IPR013320
Domain	Kelch_1	KBTBD6 KBTBD7 KLHL29 KBTBD12	2.55e-03	70	152	4	PF01344
Domain	Kelch_1	KBTBD6 KBTBD7 KLHL29 KBTBD12	2.55e-03	70	152	4	IPR006652
Domain	EGF_Lam	LAMA5 LAMB3 USH2A	2.86e-03	35	152	3	SM00180
Domain	Laminin_EGF	LAMA5 LAMB3 USH2A	2.86e-03	35	152	3	PF00053
Domain	Tyr_Pase_AS	PTPN22 PTPRU PTPRD MTMR3	2.97e-03	73	152	4	IPR016130
Domain	PTPc	PTPN22 PTPRU PTPRD	3.10e-03	36	152	3	SM00194
Domain	BROMODOMAIN_1	BRWD3 PBRM1 TAF1L	3.35e-03	37	152	3	PS00633
Domain	BTB	KBTBD6 KBTBD7 KLHL29 ZBTB34 KCND3 KBTBD12	3.58e-03	180	152	6	SM00225
Domain	Bromodomain	BRWD3 PBRM1 TAF1L	3.62e-03	38	152	3	PF00439
Domain	Laminin_EGF	LAMA5 LAMB3 USH2A	3.62e-03	38	152	3	IPR002049
Domain	TYR_PHOSPHATASE_PTP	PTPN22 PTPRU PTPRD	3.90e-03	39	152	3	PS50055
Domain	BTB/POZ_dom	KBTBD6 KBTBD7 KLHL29 ZBTB34 KCND3 KBTBD12	4.10e-03	185	152	6	IPR000210
Domain	BTB	KBTBD6 KBTBD7 KLHL29 ZBTB34 KBTBD12	4.38e-03	131	152	5	PF00651
Domain	PTPase_domain	PTPN22 PTPRU PTPRD	4.49e-03	41	152	3	IPR000242
Domain	Y_phosphatase	PTPN22 PTPRU PTPRD	4.49e-03	41	152	3	PF00102
Domain	BROMODOMAIN_2	BRWD3 PBRM1 TAF1L	4.49e-03	41	152	3	PS50014
Domain	SKP1/BTB/POZ	KBTBD6 KBTBD7 KLHL29 ZBTB34 KCND3 KBTBD12	4.55e-03	189	152	6	IPR011333
Domain	-	DOCK11 PLEKHG2 MTMR10 RANBP3L ELMO2 OSBPL5 MTMR3 RASAL1 ARAP1	4.79e-03	391	152	9	2.30.29.30
Domain	Bromodomain	BRWD3 PBRM1 TAF1L	4.81e-03	42	152	3	IPR001487
Domain	BROMO	BRWD3 PBRM1 TAF1L	4.81e-03	42	152	3	SM00297
Domain	-	BRWD3 PBRM1 TAF1L	4.81e-03	42	152	3	1.20.920.10
Domain	START	STARD13 DLC1	4.84e-03	13	152	2	SM00234
Domain	BTB-kelch_protein	KBTBD7 KLHL29 KBTBD12	5.14e-03	43	152	3	IPR017096
Domain	TYR_PHOSPHATASE_1	PTPN22 PTPRU PTPRD MTMR3	5.34e-03	86	152	4	PS00383
Domain	TYR_PHOSPHATASE_dom	PTPN22 PTPRU PTPRD MTMR3	5.56e-03	87	152	4	IPR000387
Domain	TYR_PHOSPHATASE_2	PTPN22 PTPRU PTPRD MTMR3	5.56e-03	87	152	4	PS50056
Domain	Dynein_heavy_chain_D4_dom	DNAH2 DNAH11	5.62e-03	14	152	2	IPR024317
Domain	Dynein_HC_stalk	DNAH2 DNAH11	5.62e-03	14	152	2	IPR024743
Domain	Myotubularin-like_Pase_dom	MTMR10 MTMR3	5.62e-03	14	152	2	IPR010569
Domain	Dynein_heavy_dom-2	DNAH2 DNAH11	5.62e-03	14	152	2	IPR013602
Domain	DHC_N2	DNAH2 DNAH11	5.62e-03	14	152	2	PF08393
Domain	ATPase_dyneun-rel_AAA	DNAH2 DNAH11	5.62e-03	14	152	2	IPR011704
Domain	MT	DNAH2 DNAH11	5.62e-03	14	152	2	PF12777
Domain	AAA_8	DNAH2 DNAH11	5.62e-03	14	152	2	PF12780
Domain	PPASE_MYOTUBULARIN	MTMR10 MTMR3	5.62e-03	14	152	2	PS51339
Domain	Myotubularin_fam	MTMR10 MTMR3	5.62e-03	14	152	2	IPR030564
Domain	Myotub-related	MTMR10 MTMR3	5.62e-03	14	152	2	PF06602
Domain	AAA_5	DNAH2 DNAH11	5.62e-03	14	152	2	PF07728
Domain	C2	C2CD5 WWC2 RIMS1 RASAL1 WWC1	6.14e-03	142	152	5	PS50004
Domain	DHC_fam	DNAH2 DNAH11	6.44e-03	15	152	2	IPR026983
Domain	RasGAP	GAPVD1 RASAL1	6.44e-03	15	152	2	PF00616
Domain	RAS_GTPASE_ACTIV_1	GAPVD1 RASAL1	6.44e-03	15	152	2	PS00509
Domain	START_lipid-bd_dom	STARD13 DLC1	6.44e-03	15	152	2	IPR002913
Domain	Dynein_heavy	DNAH2 DNAH11	6.44e-03	15	152	2	PF03028
Domain	START	STARD13 DLC1	6.44e-03	15	152	2	PF01852
Domain	RAS_GTPASE_ACTIV_2	GAPVD1 RASAL1	6.44e-03	15	152	2	PS50018
Domain	Dynein_heavy_dom	DNAH2 DNAH11	6.44e-03	15	152	2	IPR004273
Domain	START	STARD13 DLC1	6.44e-03	15	152	2	PS50848
Domain	ARM-like	PKP4 HSF2BP RIPOR3 MEI1 ELMO2 PKP1 SYMPK	6.69e-03	270	152	7	IPR011989
Domain	-	PTPN22 PTPRU PTPRD MTMR3	6.77e-03	92	152	4	3.90.190.10
Domain	-	KBTBD6 KBTBD7 KBTBD12	6.99e-03	48	152	3	2.120.10.80
Domain	Znf_FYVE_PHD	TCF20 KDM5A CHD3 MTMR3 RIMS1	7.08e-03	147	152	5	IPR011011
Domain	-	C2CD5 WWC2 RIMS1 RASAL1 WWC1	7.28e-03	148	152	5	2.60.40.150
Domain	Galactose-bd-like	LAMA5 LAMB3 PTPRU MEP1B	7.30e-03	94	152	4	IPR008979
Domain	MAM_1	PTPRU MEP1B	7.33e-03	16	152	2	PS00740
Domain	-	GAPVD1 RASAL1	7.33e-03	16	152	2	1.10.506.10
Domain	SAM_DOMAIN	STARD13 MAP3K20 DLC1 ARAP1	7.57e-03	95	152	4	PS50105
Pathway	REACTOME_RHO_GTPASE_CYCLE	STARD13 DOCK11 PKP4 PAK4 PLEKHG2 SOWAHC RHPN1 DLC1 ELMO2 SAMM50 TOR1AIP1 VCP ARAP1	5.91e-05	439	115	13	MM15595
Pathway	REACTOME_RHO_GTPASE_CYCLE	STARD13 DOCK11 PKP4 PAK4 PLEKHG2 SOWAHC RHPN1 DLC1 ELMO2 SAMM50 TOR1AIP1 VCP ARAP1	7.60e-05	450	115	13	M27078
Pathway	PID_INTEGRIN4_PATHWAY	LAMA5 LAMB3 ITGB4	8.32e-05	11	115	3	M158
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FLII MAN2A2 RHBDF1 SZT2 PUF60 INTS1 LAMA5 LAMB3 KTI12 CORO1B BCL9 ITGB4 CABLES1 PCNX2 RHPN1 KANSL1 TMEM259 LMX1B OSBPL5 MTMR3 DENND5A TTC38 RASAL1 ARAP1 SYMPK	3.90e-11	1105	158	25	35748872
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	FLII GAPVD1 PPAN GCFC2 TCF20 KDM5A USP24 CHD3 MED1 BCL9 C2CD5 LIG1 WWC2 KANSL1 CDT1 RIMS1 ATM SYMPK	1.73e-08	774	158	18	15302935
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	MYT1L INTS6L SFR1 KANSL1 CCSER2 KIF3C DMD UTRN WWC1	3.34e-08	151	158	9	17043677
Pubmed	Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype.	PKNOX2 PKNOX1 PBX2 PBX3	2.84e-07	13	158	4	16847320
Pubmed	Dynamic expression of MEIS1 homeoprotein in E14.5 forebrain and differentiated forebrain-derived neural stem cells.	PKNOX2 PKNOX1 PBX2 PBX3	5.38e-07	15	158	4	23756022
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	PPAN TCF20 DNAH2 SOCS6 PCNX2 XIRP2 OSBPL5 SCN9A DNAH11	1.32e-06	233	158	9	37704626
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	RHBDF1 ADAM9 PKP4 PAK4 MTMR10 C2CD5 CABLES1 DLG2 DMD UTRN TOR1AIP1	1.36e-06	377	158	11	38117590
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	MYT1L FLII KDM5A ADAM9 CEP290 RAPGEF4 FBXO11 MTMR10 TRIM52 BRWD3 PTPRD GLS MTMR3 PKNOX1 DLG2 ATM PBX2 PBX3 UTRN VCP	1.69e-06	1285	158	20	35914814
Pubmed	The PBX-regulating protein PREP1 is present in different PBX-complexed forms in mouse.	PKNOX1 PBX2 PBX3	1.82e-06	6	158	3	10381567
Pubmed	Characterization of TALE genes expression during the first lineage segregation in mammalian embryos.	PKNOX1 PBX2 PBX3	1.82e-06	6	158	3	22987645
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	FLII TCF20 KDM5A DOCK11 NHSL2 ADAM9 PKP4 DLGAP4 RAPGEF4 CORO1B BCL9 PBRM1 PTPRD TMEM259 DLG2 RIMS1 RASAL1	2.05e-06	963	158	17	28671696
Pubmed	The atypical homeoprotein Pbx1a participates in the axonal pathfinding of mesencephalic dopaminergic neurons.	LMX1B PKNOX1 PBX2 PBX3	2.81e-06	22	158	4	22748019
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	INTS6L GPBP1 PUF60 ICE2 DLGAP4 USP24 LAMB3 RIPOR3 PTPRU BCL9 LENG8 HOXB3 TCAIM PKNOX1 PBX3 RPE UTRN TLCD3A TOR1AIP1	2.93e-06	1215	158	19	15146197
Pubmed	CFAP45 deficiency causes situs abnormalities and asthenospermia by disrupting an axonemal adenine nucleotide homeostasis module.	CFAP52 DNAH17 DNAH11	3.18e-06	7	158	3	33139725
Pubmed	Regulation of Wnt/PCP signaling through p97/VCP-KBTBD7-mediated Vangl ubiquitination and endoplasmic reticulum-associated degradation.	KBTBD6 KBTBD7 VCP	3.18e-06	7	158	3	33990333
Pubmed	Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.	DNAH2 DNAH17 DNAH11	3.18e-06	7	158	3	31178125
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	FLII GAPVD1 DOCK11 RAPGEF4 HSF2BP PTPN22 MEI1 CABLES1 XIRP2 SCN9A ATM WNK4	3.18e-06	497	158	12	36774506
Pubmed	Spatial and temporal control of laminin-332 and -511 expressions during hair morphogenesis.	LAMA5 LAMB3 ITGB4	5.07e-06	8	158	3	23529140
Pubmed	Evolutionary and molecular facts link the WWC protein family to Hippo signaling.	WWC2 DLC1 WWC1	5.07e-06	8	158	3	24682284
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	GAPVD1 DOCK11 PKP4 PAK4 MAP3K20 C2CD5 CCSER2 MTMR3 LRCH4 UTRN WWC1	6.78e-06	446	158	11	24255178
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	GAPVD1 DOCK11 RNF112 CEP290 INTS1 DNAH2 LAMB3 CABLES1 MYO15B RANBP3L ATM PBX2 UTRN SYMPK	7.42e-06	736	158	14	29676528
Pubmed	Meis homeoproteins directly regulate Pax6 during vertebrate lens morphogenesis.	PKNOX1 PBX2 PBX3	7.57e-06	9	158	3	12183364
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	GAPVD1 TCF20 GPBP1 KDM5A DOCK11 PAK4 MAP3K20 PLEKHG2 WWC2 DLC1 ELMO2 CCSER2 UTRN WNK4 PPP1R12C	9.85e-06	861	158	15	36931259
Pubmed	Beta4 integrin is required for hemidesmosome formation, cell adhesion and cell survival.	LAMA5 LAMB3 ITGB4	1.48e-05	11	158	3	8707838
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	MYD88 MACROD1 CHD3 BRWD3 PCNX2 KLHL29 PKNOX2 KCND3 GLI2 OSBPL5 KCNN2 SAMM50 RIMS1 DENND5A PBX2 PBX3 GPT2 UTRN SAP130 ARAP1	1.49e-05	1489	158	20	28611215
Pubmed	Decreased myocardial nNOS, increased iNOS and abnormal ECGs in mouse models of Duchenne muscular dystrophy.	DMD UTRN	2.05e-05	2	158	2	10525423
Pubmed	WW and C2 domain-containing proteins regulate hepatic cell differentiation and tumorigenesis through the hippo signaling pathway.	WWC2 WWC1	2.05e-05	2	158	2	29116649
Pubmed	In Vivo Genome Editing Restores Dystrophin Expression and Cardiac Function in Dystrophic Mice.	DMD UTRN	2.05e-05	2	158	2	28790199
Pubmed	Metabolic dysfunction and altered mitochondrial dynamics in the utrophin-dystrophin deficient mouse model of duchenne muscular dystrophy.	DMD UTRN	2.05e-05	2	158	2	25859846
Pubmed	G-utrophin, the autosomal homologue of dystrophin Dp116, is expressed in sensory ganglia and brain.	DMD UTRN	2.05e-05	2	158	2	7731967
Pubmed	Role of dystrophin and utrophin for assembly and function of the dystrophin glycoprotein complex in non-muscle tissue.	DMD UTRN	2.05e-05	2	158	2	16710609
Pubmed	Nonclinical Exon Skipping Studies with 2'-O-Methyl Phosphorothioate Antisense Oligonucleotides in mdx and mdx-utrn-/- Mice Inspired by Clinical Trial Results.	DMD UTRN	2.05e-05	2	158	2	30672725
Pubmed	Talin, vinculin and DRP (utrophin) concentrations are increased at mdx myotendinous junctions following onset of necrosis.	DMD UTRN	2.05e-05	2	158	2	7962191
Pubmed	Does utrophin expression in muscles of mdx mice during postnatal development functionally compensate for dystrophin deficiency?	DMD UTRN	2.05e-05	2	158	2	8021701
Pubmed	Correlation of Utrophin Levels with the Dystrophin Protein Complex and Muscle Fibre Regeneration in Duchenne and Becker Muscular Dystrophy Muscle Biopsies.	DMD UTRN	2.05e-05	2	158	2	26974331
Pubmed	Overexpression of PREP-1 in F9 teratocarcinoma cells leads to a functionally relevant increase of PBX-2 by preventing its degradation.	PKNOX1 PBX2	2.05e-05	2	158	2	12871956
Pubmed	Androgen receptor agonists increase lean mass, improve cardiopulmonary functions and extend survival in preclinical models of Duchenne muscular dystrophy.	DMD UTRN	2.05e-05	2	158	2	28453658
Pubmed	A quantitative study of bioenergetics in skeletal muscle lacking utrophin and dystrophin.	DMD UTRN	2.05e-05	2	158	2	11801396
Pubmed	Apo-dystrophin-1 and apo-dystrophin-2, products of the Duchenne muscular dystrophy locus: expression during mouse embryogenesis and in cultured cell lines.	DMD UTRN	2.05e-05	2	158	2	7987307
Pubmed	Comparative analysis of the human dystrophin and utrophin gene structures.	DMD UTRN	2.05e-05	2	158	2	11861579
Pubmed	Distinct mechanical properties in homologous spectrin-like repeats of utrophin.	DMD UTRN	2.05e-05	2	158	2	30914715
Pubmed	Comparison of skeletal muscle pathology and motor function of dystrophin and utrophin deficient mouse strains.	DMD UTRN	2.05e-05	2	158	2	22284942
Pubmed	Haploinsufficiency of utrophin gene worsens skeletal muscle inflammation and fibrosis in mdx mice.	DMD UTRN	2.05e-05	2	158	2	17889902
Pubmed	Matricellular Protein CCN5 Gene Transfer Ameliorates Cardiac and Skeletal Dysfunction in mdx/utrn (±) Haploinsufficient Mice by Reducing Fibrosis and Upregulating Utrophin Expression.	DMD UTRN	2.05e-05	2	158	2	35557546
Pubmed	Characterization of the Ang/Tie2 Signaling Pathway in the Diaphragm Muscle of DMD Mice.	DMD UTRN	2.05e-05	2	158	2	37626761
Pubmed	Molecular heterogeneity of the dystrophin-associated protein complex in the mouse kidney nephron: differential alterations in the absence of utrophin and dystrophin.	DMD UTRN	2.05e-05	2	158	2	15565469
Pubmed	The junctional epithelium originates from the odontogenic epithelium of an erupted tooth.	LAMA5 ITGB4	2.05e-05	2	158	2	24785116
Pubmed	The N- and C-Terminal Domains Differentially Contribute to the Structure and Function of Dystrophin and Utrophin Tandem Calponin-Homology Domains.	DMD UTRN	2.05e-05	2	158	2	26516677
Pubmed	Assessment of cardiac function in three mouse dystrophinopathies by magnetic resonance imaging.	DMD UTRN	2.05e-05	2	158	2	22209498
Pubmed	Listeria monocytogenes infection in macrophages induces vacuolar-dependent host miRNA response.	MYD88 RELA	2.05e-05	2	158	2	22114673
Pubmed	A Protocol for Simultaneous In Vivo Imaging of Cardiac and Neuroinflammation in Dystrophin-Deficient MDX Mice Using [18F]FEPPA PET.	DMD UTRN	2.05e-05	2	158	2	37108685
Pubmed	Prevention of the dystrophic phenotype in dystrophin/utrophin-deficient muscle following adenovirus-mediated transfer of a utrophin minigene.	DMD UTRN	2.05e-05	2	158	2	10694796
Pubmed	KIBRA promotes prostate cancer cell proliferation and motility.	WWC2 WWC1	2.05e-05	2	158	2	27220053
Pubmed	Enhanced currents through L-type calcium channels in cardiomyocytes disturb the electrophysiology of the dystrophic heart.	DMD UTRN	2.05e-05	2	158	2	24337461
Pubmed	Activation of calcineurin and stress activated protein kinase/p38-mitogen activated protein kinase in hearts of utrophin-dystrophin knockout mice.	DMD UTRN	2.05e-05	2	158	2	11297940
Pubmed	ATM regulates Cdt1 stability during the unperturbed S phase to prevent re-replication.	CDT1 ATM	2.05e-05	2	158	2	24280901
Pubmed	Rescue of severely affected dystrophin/utrophin-deficient mice through scAAV-U7snRNA-mediated exon skipping.	DMD UTRN	2.05e-05	2	158	2	22388933
Pubmed	Functional correction in mouse models of muscular dystrophy using exon-skipping tricyclo-DNA oligomers.	DMD UTRN	2.05e-05	2	158	2	25642938
Pubmed	Satellite cells and utrophin are not directly correlated with the degree of skeletal muscle damage in mdx mice.	DMD UTRN	2.05e-05	2	158	2	15703201
Pubmed	Utrophin suppresses low frequency oscillations and coupled gating of mechanosensitive ion channels in dystrophic skeletal muscle.	DMD UTRN	2.05e-05	2	158	2	25941878
Pubmed	Duchenne muscular dystrophy and the neuromuscular junction: the utrophin link.	DMD UTRN	2.05e-05	2	158	2	9297964
Pubmed	SERCA1 overexpression minimizes skeletal muscle damage in dystrophic mouse models.	DMD UTRN	2.05e-05	2	158	2	25652448
Pubmed	Utrophin Compensates dystrophin Loss during Mouse Spermatogenesis.	DMD UTRN	2.05e-05	2	158	2	28785010
Pubmed	Restoration of all dystrophin protein interactions by functional domains in trans does not rescue dystrophy.	DMD UTRN	2.05e-05	2	158	2	16307000
Pubmed	Expression of the dystrophin isoform Dp116 preserves functional muscle mass and extends lifespan without preventing dystrophy in severely dystrophic mice.	DMD UTRN	2.05e-05	2	158	2	21949353
Pubmed	Dystrophin and utrophin "double knockout" dystrophic mice exhibit a spectrum of degenerative musculoskeletal abnormalities.	DMD UTRN	2.05e-05	2	158	2	23097179
Pubmed	The role of utrophin and Dp71 for assembly of different dystrophin-associated protein complexes (DPCs) in the choroid plexus and microvasculature of the brain.	DMD UTRN	2.05e-05	2	158	2	15501597
Pubmed	Enhanced expression of the alpha 7 beta 1 integrin reduces muscular dystrophy and restores viability in dystrophic mice.	DMD UTRN	2.05e-05	2	158	2	11257121
Pubmed	Identifying Cancer-Relevant Mutations in the DLC START Domain Using Evolutionary and Structure-Function Analyses.	STARD13 DLC1	2.05e-05	2	158	2	33142932
Pubmed	β4 integrin marks interstitial myogenic progenitor cells in adult murine skeletal muscle.	ITGB4 DMD	2.05e-05	2	158	2	22205679
Pubmed	Systemic human minidystrophin gene transfer improves functions and life span of dystrophin and dystrophin/utrophin-deficient mice.	DMD UTRN	2.05e-05	2	158	2	18973234
Pubmed	Renin-angiotensin-aldosterone system inhibitors improve membrane stability and change gene-expression profiles in dystrophic skeletal muscles.	DMD UTRN	2.05e-05	2	158	2	27881412
Pubmed	Dystrophins, utrophins, and associated scaffolding complexes: role in mammalian brain and implications for therapeutic strategies.	DMD UTRN	2.05e-05	2	158	2	20625423
Pubmed	Utrophin influences mitochondrial pathology and oxidative stress in dystrophic muscle.	DMD UTRN	2.05e-05	2	158	2	29065908
Pubmed	Stabilization of the cardiac sarcolemma by sarcospan rescues DMD-associated cardiomyopathy.	DMD UTRN	2.05e-05	2	158	2	31039133
Pubmed	Developmentally regulated expression and localization of dystrophin and utrophin in the human fetal brain.	DMD UTRN	2.05e-05	2	158	2	11796130
Pubmed	Dystrophin and dystrophin-related protein in the brains of normal and mdx mice.	DMD UTRN	2.05e-05	2	158	2	8159184
Pubmed	Dystrophin and utrophin: genetic analyses of their role in skeletal muscle.	DMD UTRN	2.05e-05	2	158	2	10679963
Pubmed	TAT-μUtrophin mitigates the pathophysiology of dystrophin and utrophin double-knockout mice.	DMD UTRN	2.05e-05	2	158	2	21565990
Pubmed	Generation and characterization of transgenic mice with the full-length human DMD gene.	DMD UTRN	2.05e-05	2	158	2	18083704
Pubmed	Prognostic significance of pre B cell leukemia transcription factor 2 (PBX2) expression in non-small cell lung carcinoma.	PBX2 VCP	2.05e-05	2	158	2	19356220
Pubmed	Dystrophin and dystrophin-related protein (utrophin) distribution in normal and dystrophin-deficient skeletal muscles.	DMD UTRN	2.05e-05	2	158	2	8186702
Pubmed	Contemporary cardiac issues in Duchenne muscular dystrophy. Working Group of the National Heart, Lung, and Blood Institute in collaboration with Parent Project Muscular Dystrophy.	DMD UTRN	2.05e-05	2	158	2	25940966
Pubmed	Cardiac dysfunction and pathology in the dystrophin and utrophin-deficient mouse during development of dilated cardiomyopathy.	DMD UTRN	2.05e-05	2	158	2	22266080
Pubmed	Postnatal overexpression of the CT GalNAc transferase inhibits muscular dystrophy in mdx mice without altering muscle growth or neuromuscular development: evidence for a utrophin-independent mechanism.	DMD UTRN	2.05e-05	2	158	2	17300937
Pubmed	Early treatment with lisinopril and spironolactone preserves cardiac and skeletal muscle in Duchenne muscular dystrophy mice.	DMD UTRN	2.05e-05	2	158	2	21768542
Pubmed	Social stress is lethal in the mdx model of Duchenne muscular dystrophy.	DMD UTRN	2.05e-05	2	158	2	32192914
Pubmed	Metabolic remodeling of dystrophic skeletal muscle reveals biological roles for dystrophin and utrophin in adaptation and plasticity.	DMD UTRN	2.05e-05	2	158	2	33359740
Pubmed	Utrophin regulates modal gating of mechanosensitive ion channels in dystrophic skeletal muscle.	DMD UTRN	2.05e-05	2	158	2	24879867
Pubmed	Increased vulnerability to kainate-induced seizures in utrophin-knockout mice.	DMD UTRN	2.05e-05	2	158	2	12028357
Pubmed	Excitation-contraction coupling alterations in mdx and utrophin/dystrophin double knockout mice: a comparative study.	DMD UTRN	2.05e-05	2	158	2	20130206
Pubmed	Analysis of gene expression differences between utrophin/dystrophin-deficient vs mdx skeletal muscles reveals a specific upregulation of slow muscle genes in limb muscles.	DMD UTRN	2.05e-05	2	158	2	16525850
Pubmed	Distribution of dystrophin- and utrophin-associated protein complexes during activation of human neutrophils.	DMD UTRN	2.05e-05	2	158	2	20434517
Pubmed	Plasma lipidomic analysis shows a disease progression signature in mdx mice.	DMD UTRN	2.05e-05	2	158	2	34155298
Pubmed	Dystrophic changes in extraocular muscles after gamma irradiation in mdx:utrophin(+/-) mice.	DMD UTRN	2.05e-05	2	158	2	24466085
Pubmed	The Angiotensin Converting Enzyme Inhibitor Lisinopril Improves Muscle Histopathology but not Contractile Function in a Mouse Model of Duchenne Muscular Dystrophy.	DMD UTRN	2.05e-05	2	158	2	27110493
Pubmed	Rapid depletion of muscle progenitor cells in dystrophic mdx/utrophin-/- mice.	DMD UTRN	2.05e-05	2	158	2	24781208
Pubmed	Isolation and characterization of a genomic clone from the murine utrophin locus.	DMD UTRN	2.05e-05	2	158	2	8268660
Pubmed	Phosphorylation-Dependent Regulation of the DNA Damage Response of Adaptor Protein KIBRA in Cancer Cells.	ATM WWC1	2.05e-05	2	158	2	26929199
Pubmed	Flightless I homolog negatively modulates the TLR pathway.	MYD88 FLII	2.05e-05	2	158	2	16424162
Cytoband	9q33.3	GAPVD1 ZBTB34 LMX1B ADGRD2 PBX3	1.81e-07	37	158	5	9q33.3
Cytoband	Ensembl 112 genes in cytogenetic band chr9q33	GAPVD1 ZBTB34 LMX1B ADGRD2 PBX3	1.21e-04	138	158	5	chr9q33
GeneFamily	TALE class homeoboxes and pseudogenes	MEIS3P1 PKNOX2 PKNOX1 PBX2 PBX3	3.25e-07	26	103	5	526
GeneFamily	Dyneins, axonemal	DNAH2 DNAH17 DNAH11	1.15e-04	17	103	3	536
GeneFamily	C2 and WW domain containing	WWC2 WWC1	1.91e-04	4	103	2	838
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	KBTBD6 KBTBD7 KLHL29 ZBTB34 KBTBD12	1.02e-03	134	103	5	861
GeneFamily	Laminin subunits	LAMA5 LAMB3	2.04e-03	12	103	2	626
GeneFamily	Fibronectin type III domain containing	PTPRU ITGB4 PTPRD CNTN3 USH2A	2.22e-03	160	103	5	555
GeneFamily	Myotubularins\|Phosphoinositide phosphatases	MTMR10 MTMR3	3.22e-03	15	103	2	903
GeneFamily	Integrator complex	INTS6L INTS1	3.22e-03	15	103	2	1366
GeneFamily	StAR related lipid transfer domain containing	STARD13 DLC1	3.22e-03	15	103	2	759
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	DMD UTRN	4.63e-03	18	103	2	91
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal-Intermediate\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	TCF20 KBTBD6 MEI1 LENG8 HOXB3 XIRP2 TMEM259 GLS	6.03e-07	200	158	8	a3fcd901cb281920f1bafdfd676399a6dc37355e
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	PTPRU XIRP2 KCND3 LMX1B SCN9A PBX3 TMEM255A	2.19e-06	166	158	7	6a6ed5c7a43fee9a8a9be42dfa99303815b8e8ef
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RHBDF1 LAMB3 ITGB4 PTCD2 PKP1 PBX2 RASAL1	4.81e-06	187	158	7	a6a112689d1c9049f57935ad9d2f4955538427de
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	RAPGEF4 LAMB3 LMX1B SCN9A DMD RASAL1 WWC1	5.72e-06	192	158	7	b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCell	droplet-Fat-Mat-18m-Endothelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKP4 RAPGEF4 LAMA5 ITGB4 PLN ENG UTRN	5.92e-06	193	158	7	54024a373e42e1c0bcc327dc084564b83b63a9d4
ToppCell	droplet-Fat-Mat-18m-Endothelial-endothelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKP4 RAPGEF4 LAMA5 ITGB4 PLN ENG UTRN	5.92e-06	193	158	7	81d908594d2983ba7e7c1ec25afdde4315d9690e
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PKP4 MBOAT2 PTPRD CNTN3 RIMS1 GPT2 WWC1	6.99e-06	198	158	7	af399569c718f5fd971d73a7926768c9311002a3
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells-Ciliated\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CFAP276 RHPN1 CFAP52 SLC24A4 USH2A DNAH11	1.87e-05	154	158	6	9ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CFAP276 RHPN1 CFAP52 SLC24A4 USH2A DNAH11	1.87e-05	154	158	6	58072ce422d09f2de602580325eaac6c4ec6c136
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF4 PLEKHG2 DLC1 CNTN3 ADGRD2 ENG	2.40e-05	161	158	6	1b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRRC63 CHD3 MTMR10 HOXB3 GLS DLG2	3.25e-05	170	158	6	928e42c51a7079c506f21c669c4e4c1a0df84d77
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK11 RIPOR3 KLHL29 HOXB3 DNAH17 DNAH11	3.25e-05	170	158	6	5d5f208682be21ed58320f5fc083a7898f8712da
ToppCell	COVID-19_Convalescent-Hematopoietic_SC\|COVID-19_Convalescent / Disease group, lineage and cell class	LRRC63 MACROD1 RIPOR3 DLC1 XIRP2 TLCD3A	3.25e-05	170	158	6	8a73d5334eed1cd9fdcc3ebeae0bdf9f945c228a
ToppCell	PBMC-Convalescent-Hematopoietic-HSPC-HSPC-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	LRRC63 MACROD1 RIPOR3 DLC1 XIRP2 TLCD3A	3.47e-05	172	158	6	8fd3db757d54949bd583d5f0eadf63a32342cb9d
ToppCell	PBMC-Convalescent-Hematopoietic-HSPC\|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)	LRRC63 MACROD1 RIPOR3 DLC1 XIRP2 TLCD3A	3.47e-05	172	158	6	da78f7a71b7f05c5c484c9ed19ba37c55d35e870
ToppCell	PBMC-Convalescent-Hematopoietic-HSPC-HSPC\|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)	LRRC63 MACROD1 RIPOR3 DLC1 XIRP2 TLCD3A	3.47e-05	172	158	6	382cb5fea099110eb026a8bba6cf4c28763ea52f
ToppCell	Multiple_Sclerosis-Lymphocyte-T_NK-ILC\|Multiple_Sclerosis / Disease, Lineage and Cell Type	MAN2A2 MBOAT2 WWC2 SCN9A PTH2 WWC1	3.71e-05	174	158	6	7c50bf9da37711266cc077eef4e54b58463f1d37
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK11 MTMR10 KLHL29 DNAH17 UTRN DNAH11	4.08e-05	177	158	6	da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCell	Mid-temporal_gyrus_(MTG)\|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NHSL2 CHD3 XIRP2 KCND3 DMD RASAL1	4.21e-05	178	158	6	ad187db4c40b9078d54dd915c143e0172b2f47b8
ToppCell	390C-Lymphocytic-ILC-ILC-1\|390C / Donor, Lineage, Cell class and subclass (all cells)	INTS6L MAN2A2 PTPN22 MEI1 MBOAT2 MTMR10	4.34e-05	179	158	6	e7045e27f0eb88f552b31c04b56d78e5ccd7a36c
ToppCell	RA-16._Neuronal\|RA / Chamber and Cluster_Paper	ITGB4 KLHL29 DLC1 SCN9A GPT2 TMEM255A	4.48e-05	180	158	6	5842febfdabac61ce970254fb0ef17a628f1b8c0
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRRC63 DOCK11 MTMR10 KLHL29 UTRN WWC1	4.62e-05	181	158	6	071f9bb5d39070cdc473d9b0e094d196bc702b56
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK11 FANCC KLHL29 PTPRD DLG2 WWC1	4.62e-05	181	158	6	6956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell	Basal\|World / shred by cell class for mouse tongue	MAN2A2 MAP3K20 LAMA5 LAMB3 ITGB4 WWC2	4.91e-05	183	158	6	c6729a207526ff4aa48176207b9353176f631fea
ToppCell	facs-Liver-Hepatocytes-24m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAM9 MACROD1 PM20D1 PTPRD GPT2 WWC1	4.91e-05	183	158	6	d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRRC63 DOCK11 MTMR10 HOXB3 WWC1 DNAH11	4.91e-05	183	158	6	cfae90c309622b5d499e62a3a8a8b9746478d28d
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRD XIRP2 SCN9A DMD USH2A DNAH11	5.06e-05	184	158	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRD XIRP2 SCN9A DMD USH2A DNAH11	5.06e-05	184	158	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRD XIRP2 SCN9A DMD USH2A DNAH11	5.06e-05	184	158	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LRRC63 DOCK11 MTMR10 KLHL29 WWC1 DNAH11	5.06e-05	184	158	6	da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MAP3K20 PLEKHG2 DLC1 GLI2 DMD UTRN	5.21e-05	185	158	6	51dfe6ac7df8b330343b37e3bee71e5c65267189
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK11 RAPGEF4 PTPRD GLS DMD DNAH11	5.21e-05	185	158	6	4e40d3103ebf4a7066b7ce300b6ef700ba0e2863
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 MBOAT2 MTMR10 GLS DLG2 RASAL1	5.21e-05	185	158	6	d602a9b35e86e6f2a14a58e40fc4fb97f5fa3b08
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MAP3K20 PLEKHG2 DLC1 GLI2 DMD UTRN	5.21e-05	185	158	6	a8c02cec3c414f3a0da9f2d6d28ce563b0030705
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAPGEF4 PTPRD KCND3 GLS DMD DNAH11	5.37e-05	186	158	6	16092819e9148dfe64f07c737652b6e533e699f7
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAP3K20 RIPOR3 DLC1 GLI2 DMD DNAH11	5.53e-05	187	158	6	ec4b694487cc446999c7b27b119950a4f252c4b3
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK11 KLHL29 PTPRD SLC28A1 DLG2 WWC1	5.53e-05	187	158	6	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAP3K20 RIPOR3 DLC1 GLI2 DMD DNAH11	5.53e-05	187	158	6	530e4e6d91b5c0d9aa4543caa2b734a1674c5788
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 MBOAT2 MTMR10 GLS DLG2 RASAL1	5.53e-05	187	158	6	e3095455d2f255854f339f6b05fa87852af0700f
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LRRC63 DOCK11 FANCC KLHL29 WWC1 DNAH11	5.87e-05	189	158	6	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	COVID-19-kidney-TAL\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PKP4 HOXB3 RANBP3L WNK4 RASAL1 WWC1	6.22e-05	191	158	6	fe55475ce0666ab5122447a813dc2369e24947b8
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAP3K20 DLC1 GLI2 DMD PLN DNAH11	6.40e-05	192	158	6	24e2f15f5767a97eb3b389922bcfd7b13805e1ce
ToppCell	Mesenchymal-matrix_fibroblast_1_cell\|World / Lineage, Cell type, age group and donor	NHSL2 PKNOX2 HOXB3 PTPRD GLI2 CNTN3	6.59e-05	193	158	6	acad568621ed677031797b8c2e34dafea798d681
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RIPOR3 PKNOX2 DLC1 GLI2 DMD ENG	6.78e-05	194	158	6	81713e0409e8be695ba5dfdc67a997b33435dd9e
ToppCell	facs-Trachea-nan-3m-Epithelial\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA5 LAMB3 ITGB4 RHPN1 NPY WWC1	6.78e-05	194	158	6	3701ca87c6dc9ccd7b4146e56371546174d26c36
ToppCell	facs-Trachea-nan-3m-Epithelial-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA5 LAMB3 ITGB4 RHPN1 NPY WWC1	6.78e-05	194	158	6	65f9bf126be26114c2c3f4c46d48318986212a92
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PKP4 RAPGEF4 LAMA5 MBOAT2 RIMS1 ENG	6.78e-05	194	158	6	68004855b23fe1e31e8452d70effabc78a4a0bd3
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MAP3K20 DLC1 GLI2 DMD PLN UTRN	6.78e-05	194	158	6	ebb038f94f49f5c655578d1b018676e10c6b7e3c
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RIPOR3 PKNOX2 DLC1 GLI2 DMD ENG	6.78e-05	194	158	6	627cffe2d448e74fc5df92e74e5b922a73304137
ToppCell	droplet-Fat-Mat-18m-Endothelial-Cd36+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKP4 LAMA5 ITGB4 PLN ENG UTRN	6.78e-05	194	158	6	74d0eaa76f6d9af14110dfe5b4bf9751b99ff6e3
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAP3K20 DLC1 GLI2 DMD PLN UTRN	7.18e-05	196	158	6	b8759e6231e0254797d6c30930407b79440c57bb
ToppCell	(7)_Epithelial-I_(AT1)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	KDM5A LAMA5 LAMB3 WWC2 LRCH4 WWC1	7.18e-05	196	158	6	150554fa06868d29b0608189862eef6505ba757f
ToppCell	COPD-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	STARD13 PAK4 RAPGEF4 MBOAT2 RIMS1 ENG	7.38e-05	197	158	6	30dbc05ea66892d2e18ff375ffa86d1db7bc4083
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_airway_neuro-secretory\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	MYT1L LMX1B SCN9A DLG2 NPY RASAL1	7.38e-05	197	158	6	ff4df77117165b6b25315e29b0722cc136eba607
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CEP290 DNAH2 RHPN1 DMD WNK4 DNAH11	7.38e-05	197	158	6	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MAP3K20 DLC1 GLI2 DMD ENG UTRN	7.38e-05	197	158	6	9b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCell	facs-Tongue-nan-3m-Epithelial-basal_cell_of_epidermis\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF20 GPBP1 MAP3K20 LAMB3 ITGB4 VCP	7.59e-05	198	158	6	22559b161e67b49fe8028bfaf861e069063599f5
ToppCell	COVID-19-lung-Fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	NHSL2 PKNOX2 PTPRD KCND3 GLI2 DLG2	7.59e-05	198	158	6	df3de77216f5c5d6141ec44d01c56b942f611838
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6\|World / Primary Cells by Cluster	MYT1L CEP290 CHD3 PTPRD DLG2 NPY	7.80e-05	199	158	6	1b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MYD88 SZT2 DOCK11 DENND5A ENG UTRN	7.80e-05	199	158	6	379bbd9cecf466b902411c54d74bd9885285b1ba
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal\|World / Primary Cells by Cluster	MYT1L CEP290 CHD3 PTPRD DLG2 NPY	7.80e-05	199	158	6	4bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	PKP4 KANSL1 CDT1 DENND5A DMD UTRN	7.80e-05	199	158	6	358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / Treatment groups by lineage, cell group, cell type	CEP290 LAMB3 PTPRU WWC2 UTRN WWC1	8.02e-05	200	158	6	2dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCell	Tracheal\|World / Cell types per location group and 10X technology with lineage, and cell group designations	PKP4 ITGB4 GLI2 DMD GPT2 RASAL1	8.02e-05	200	158	6	682960e28542a3d6c119047cd0131941932cfdea
ToppCell	COVID-19_Convalescent-PLT_3\|World / Disease Group and Platelet Clusters	PAK4 KTI12 ATM DMD WWC1	1.29e-04	137	158	5	bb54bb81b450462ad521b57e1a07a80ce1678e67
Drug	Fenofibrate [49562-28-9]; Up 200; 11uM; MCF7; HT_HG-U133A	KDM5A LAMB3 HS1BP3 PTPRU MED1 TRIM52 CCSER2 PKNOX1 RASAL1	8.67e-06	196	156	9	7432_UP
Drug	Guanabenz acetate [23256-50-0]; Up 200; 13.8uM; PC3; HG-U133A	TBRG4 PKP4 CEP290 BCL9 LIG1 WWC2 MTMR3 RNF41 VCP	8.67e-06	196	156	9	1961_UP
Drug	Paroxetine maleate [64006-44-6]; Down 200; 1uM; PC3; HT_HG-U133A	USP24 CHD3 FANCC GLS CDT1 ATM UTRN TTC38 WWC1	9.03e-06	197	156	9	4556_DN
Drug	minocycline; Down 200; 10.5uM; MCF7; HT_HG-U133A_EA	GCFC2 KDM5A DLGAP4 CEP290 LAMA5 MLH3 PBRM1 GLS CCSER2	9.41e-06	198	156	9	1135_DN
Drug	Oxethazaine [126-27-2]; Down 200; 8.6uM; MCF7; HT_HG-U133A	CEP290 RELA CHD3 SOWAHC ITGB4 MLH3 UTRN ARAP1 SYMPK	9.79e-06	199	156	9	1484_DN
Drug	Fenoterol hydrobromide [1944-12-3]; Down 200; 10.4uM; HL60; HT_HG-U133A	CEP290 PAK4 MAP3K20 WWC2 TMEM259 PKP1 ATM SYMPK	5.53e-05	192	156	8	2378_DN
Drug	Sulfamonomethoxine [1220-83-3]; Down 200; 14.2uM; HL60; HT_HG-U133A	RHBDF1 PKP4 PCNX2 CCSER2 KIF3C ENG UTRN ARAP1	5.95e-05	194	156	8	2742_DN
Drug	Estropipate [7280-37-7]; Down 200; 9.2uM; MCF7; HT_HG-U133A	DLGAP4 SOCS6 TMEM259 GLS DNAH17 MTMR3 KIF3C SYMPK	5.95e-05	194	156	8	6068_DN
Drug	Acetylsalicylsalicylic acid [530-75-6]; Down 200; 13.4uM; HL60; HG-U133A	DLGAP4 FBXO11 CHD3 MLH3 ELMO2 ATM UTRN ARAP1	5.95e-05	194	156	8	1377_DN
Drug	Spiramycin [8025-81-8]; Down 200; 4.8uM; MCF7; HT_HG-U133A	PTPN22 FANCC GLS KCNN2 KIF3C ATM UTRN ARAP1	5.95e-05	194	156	8	3938_DN
Drug	Lumicolchicine gamma [6901-14-0]; Down 200; 10uM; MCF7; HT_HG-U133A	KDM5A CEP290 LAMA5 MBOAT2 TMEM259 PKNOX1 ATM ARAP1	6.17e-05	195	156	8	3254_DN
Drug	Thiamphenicol [15318-45-3]; Up 200; 11.2uM; MCF7; HT_HG-U133A	DLGAP4 SOWAHC WWC2 TMEM259 MTMR3 KIF3C TTC38 SYMPK	6.17e-05	195	156	8	7033_UP
Drug	Famotidine [76824-35-6]; Up 200; 11.8uM; MCF7; HT_HG-U133A	PTPN22 KLHL29 PKNOX2 DLC1 KCND3 LMX1B GLS ARAP1	6.39e-05	196	156	8	5011_UP
Drug	Florfenicol [73231-34-2]; Up 200; 11.2uM; HL60; HT_HG-U133A	STARD13 SZT2 PAK4 MBOAT2 HOXB3 MLH3 PKNOX1 ARAP1	6.39e-05	196	156	8	3083_UP
Drug	Liothyronine [6893-02-3]; Down 200; 6.2uM; PC3; HT_HG-U133A	SZT2 RELA CHD3 BCL9 PCNX2 TMEM259 CCSER2 TTC38	6.39e-05	196	156	8	6602_DN
Drug	rosiglitazone; Up 200; 10uM; MCF7; HT_HG-U133A_EA	GCFC2 MAN2A2 CEP290 PTPRU ITGB4 MLH3 ELMO2 TTC38	6.63e-05	197	156	8	1071_UP
Drug	Deoxycorticosterone [64-85-7]; Up 200; 12.2uM; MCF7; HT_HG-U133A	KDM5A PKNOX2 MLH3 DLC1 KCND3 KIF3C RIMS1 RASAL1	6.63e-05	197	156	8	5357_UP
Drug	Minoxidil [38304-91-5]; Down 200; 19.2uM; MCF7; HT_HG-U133A	CEP290 CHD3 MED1 ITGB4 PCNX2 MLH3 MTMR3 UTRN	6.63e-05	197	156	8	1496_DN
Drug	Aspartic acid, N-acetyl (R,S) [997-55-7]; Down 200; 22.8uM; MCF7; HT_HG-U133A	MAN2A2 CEP290 INTS1 CHD3 BCL9 MLH3 TMEM259 ARAP1	6.63e-05	197	156	8	3265_DN
Drug	Harmaline hydrochloride dihydrate [6027-98-1]; Up 200; 14uM; MCF7; HT_HG-U133A	CEP290 LAMB3 PTPN22 SOCS6 FANCC HOXB3 ARAP1 SYMPK	6.63e-05	197	156	8	4968_UP
Drug	Cyclobenzaprine hydrochloride [6202-23-9]; Down 200; 12.8uM; HL60; HT_HG-U133A	FLII PAK4 USP24 SOCS6 CCSER2 PKNOX1 UTRN TLCD3A	6.87e-05	198	156	8	1332_DN
Drug	Thalidomide [50-35-1]; Up 200; 15.4uM; HL60; HG-U133A	GCFC2 MAN2A2 SZT2 DLC1 ELMO2 EIF4EBP2 CCSER2 RASAL1	6.87e-05	198	156	8	1411_UP
Drug	Dimaprit dihydrochloride [23256-33-9]; Up 200; 17uM; MCF7; HT_HG-U133A	DLGAP4 ITGB4 MEP1B KLHL29 DLC1 RIMS1 UTRN TTC38	6.87e-05	198	156	8	6520_UP
Disease	autism spectrum disorder (implicated_via_orthology)	TCF20 KDM5A PKP4 DLGAP4 EIF4EBP2 PKP1 RIMS1	1.51e-05	152	153	7	DOID:0060041 (implicated_via_orthology)
Disease	Opioid use measurement	PTPRD KCND3 PBX3	5.94e-05	15	153	3	EFO_0009937
Disease	leukemia (implicated_via_orthology)	MEIS3P1 PKNOX2 ATM	1.25e-04	19	153	3	DOID:1240 (implicated_via_orthology)
Disease	atrial fibrillation	LRRC63 HS1BP3 MEI1 FANCC SLC24A4 KCND3 KCNN2 ADGRD2 KIF3C	1.45e-04	371	153	9	EFO_0000275
Disease	Herlitz Disease	LAMB3 ITGB4	1.59e-04	4	153	2	C0079683
Disease	gonadal dysgenesis (implicated_via_orthology)	STARD13 DLC1	1.59e-04	4	153	2	DOID:14447 (implicated_via_orthology)
Disease	Epidermolysis Bullosa Progressiva	LAMB3 ITGB4	1.59e-04	4	153	2	C0079297
Disease	Alzheimer disease, polygenic risk score	TCF20 MAP3K20 FBXO11 KANSL1 SLC24A4 MTMR3 PTCD2 DLG2 RIMS1 GPT2 SYMPK	2.54e-04	586	153	11	EFO_0030082, MONDO_0004975
Disease	Adult junctional epidermolysis bullosa (disorder)	LAMB3 ITGB4	2.64e-04	5	153	2	C0268374
Disease	EPIDERMOLYSIS BULLOSA, JUNCTIONAL, LOCALISATA VARIANT (disorder)	LAMB3 ITGB4	2.64e-04	5	153	2	C2608084
Disease	junctional epidermolysis bullosa non-Herlitz type (implicated_via_orthology)	LAMB3 ITGB4	2.64e-04	5	153	2	DOID:0060738 (implicated_via_orthology)
Disease	smoking status measurement	MYT1L GAPVD1 TBRG4 TCF20 MAP3K20 FBXO11 CHD3 KLHL29 HOXB3 DLC1 PTPRD KANSL1 CNTN3 RIMS1 USH2A UTRN	3.61e-04	1160	153	16	EFO_0006527
Disease	Junctional Epidermolysis Bullosa	LAMB3 ITGB4	3.95e-04	6	153	2	C0079301
Disease	neutropenia, response to metamizole, Drug-induced agranulocytosis	STARD13 PTPRU	3.95e-04	6	153	2	EFO_0010971, HP_0012235, MONDO_0001475
Disease	lung small cell carcinoma (is_implicated_in)	LAMB3 PBRM1 ATM	4.07e-04	28	153	3	DOID:5409 (is_implicated_in)
Disease	susceptibility to mononucleosis measurement	MYT1L DNAH2 PTPRD DMD	4.62e-04	69	153	4	EFO_0008403
Disease	junctional epidermolysis bullosa (is_implicated_in)	LAMB3 ITGB4	5.51e-04	7	153	2	DOID:3209 (is_implicated_in)
Disease	ventral diencephalon volume measurement	CORO1B KANSL1	5.51e-04	7	153	2	EFO_0010337
Disease	restless legs syndrome (implicated_via_orthology)	MEIS3P1 PKNOX2	7.33e-04	8	153	2	DOID:0050425 (implicated_via_orthology)
Disease	lung non-small cell carcinoma (is_implicated_in)	MYD88 FBXO11 RELA PBRM1 ATM	8.08e-04	139	153	5	DOID:3908 (is_implicated_in)
Disease	Colorectal Carcinoma	LAMB3 CORO1B PTPRU CABLES1 LIG1 MLH3 DLC1 PTPRD KCND3 PKNOX1 DMD	1.13e-03	702	153	11	C0009402
Disease	cystic kidney disease (implicated_via_orthology)	CEP290 LAMA5	1.17e-03	10	153	2	DOID:2975 (implicated_via_orthology)
Disease	congestive heart failure (implicated_via_orthology)	MED1 PLN ENG	1.26e-03	41	153	3	DOID:6000 (implicated_via_orthology)
Disease	Macrocephaly	CHD3 BRWD3	1.42e-03	11	153	2	C0221355
Disease	status epilepticus (biomarker_via_orthology)	ADAM9 ATM DMD NPY	1.85e-03	100	153	4	DOID:1824 (biomarker_via_orthology)
Disease	Modic type vertebral endplate changes	PTPRD DLG2	2.01e-03	13	153	2	HP_0030775
Disease	advanced glycosylation end product-specific receptor, soluble measurement	KANSL1 PBX2	2.01e-03	13	153	2	EFO_0020131
Disease	ocular hypertension, response to triamcinolone acetonide	GCFC2 ITGB4 DENND5A	2.11e-03	49	153	3	EFO_0006954, EFO_1001069
Disease	multiple myeloma, monoclonal gammopathy	KIF3C DNAH11	2.33e-03	14	153	2	EFO_0000203, EFO_0001378
Disease	Intellectual Disability	MYT1L TCF20 KDM5A PUF60 CHD3 BRWD3 KANSL1 GPT2	2.39e-03	447	153	8	C3714756
Disease	Neoplasm of uncertain or unknown behavior of bladder	FANCC ATM	2.68e-03	15	153	2	C0496930
Disease	Benign neoplasm of bladder	FANCC ATM	2.68e-03	15	153	2	C0154017
Disease	Carcinoma in situ of bladder	FANCC ATM	2.68e-03	15	153	2	C0154091
Disease	Muscle hypotonia	INTS1 KANSL1	3.45e-03	17	153	2	C0026827
Disease	Amelogenesis imperfecta	LAMB3 SLC24A4	3.45e-03	17	153	2	cv:C0002452
Disease	colorectal cancer (is_implicated_in)	MYD88 MLH3 DLC1 ATM	3.69e-03	121	153	4	DOID:9256 (is_implicated_in)
Disease	PROSTATE CANCER, HEREDITARY, 1	CHD3 PKNOX2 ATM	3.77e-03	60	153	3	C4722327
Disease	Carcinoma of bladder	FANCC ATM	3.87e-03	18	153	2	C0699885
Disease	Hereditary Non-Polyposis Colon Cancer Type 2	MLH3 ATM	4.31e-03	19	153	2	C1333991
Disease	Colorectal cancer, hereditary nonpolyposis, type 1	MLH3 ATM	4.31e-03	19	153	2	C2936783
Disease	parental longevity	MYT1L GAPVD1 MAN2A2 RAPGEF4 MAP3K20 PTPRD CCSER2 NPY	4.37e-03	494	153	8	EFO_0007796
Disease	urate measurement, bone density	LAMA5 RIPOR3 PTPRD GLI2 DLG2 USH2A UTRN RASAL1 DNAH11	5.14e-03	619	153	9	EFO_0003923, EFO_0004531
Disease	Global developmental delay	TCF20 SZT2 INTS1 CHD3	5.16e-03	133	153	4	C0557874

Protein segments in the cluster

Peptide	Gene	Start	Entry
NRAMRRVSSVPSRAQ	PKP4	206	Q99569
RSRRERILTLESMNP	GPT2	41	Q8TD30
RVPRENMLSRFAQVL	ACOX2	261	Q99424
LARTMDIPRSVQNFR	ALDH8A1	101	Q9H2A2
RLSQRDMQRVEPSLL	ACCS	116	Q96QU6
SRPVESIMTLNVRRA	C4orf47	281	A7E2U8
QEVLARARNLISPRM	CDT1	361	Q9H211
RARNLISPRMEKALS	CDT1	366	Q9H211
ISRRNVLSDSRPAMA	CORO1B	406	Q9BR76
TSNTLFRTLLEMQPR	DNAH11	4221	Q96DT5
PNMDISSSPNIRLRR	BRWD3	686	Q6RI45
RKFLLDRRNSPMAQT	EIF4EBP2	56	Q13542
TSLQRSDSSQPMLLR	DMD	3616	P11532
MRSSTLQDPRRRDPQ	CDC14C	1	A4D256
RNRLNSAPDMRVALS	FAM200A	541	Q8TCP9
NPRRSLDRLDSVDML	DLGAP4	411	Q9Y2H0
RTVFMRLNIISPDLS	ENG	566	P17813
RLNSTPTITSMRRDA	CFAP276	46	Q5T5A4
PRTRLRMASRIIINE	SLC24A4	336	Q8NFF2
LTRREVARTMDPNTL	RASAL1	326	O95294
PRRGLLDQLTRMRSN	INTS6L	516	Q5JSJ4
LIREMRTQRPSLVQT	PTPN22	261	Q9Y2R2
RVLSPEAVRNTLSLM	GLS	446	O94925
MTQLRQVLESRLQRP	LRCH4	541	O75427
SRFMERNPLTNAIIR	PM20D1	321	Q6GTS8
VMNLLREQSRTRPIS	PBX3	181	P40426
SSRMTRRDPLTNKVA	DHRS4L2	21	Q6PKH6
SLRMRTPSNLAAARL	PBRM1	296	Q86U86
MNLLREQSRTRPVAP	PBX2	191	P40425
NLPATRLRSMQELST	KCND3	561	Q9UK17
PRMRLLQSLLDTRCV	FLII	761	Q13045
SSQRDLAVRRMPSLL	MBOAT2	161	Q6ZWT7
RPLTMAELSRLRRQF	KTI12	311	Q96EK9
PLRAQLRMLASQASA	INTS1	1476	Q8N201
NSLERRSVRMKRPSS	WWC1	961	Q8IX03
VLSRMLRQQRSGPLE	MTMR10	691	Q9NXD2
LNQQPRLTKLTRMRT	GPBP1	281	Q86WP2
MRPLSNLSASRRNLH	KCNN2	11	Q9H2S1
RNRVATMPVRLLRDS	HSPB9	26	Q9BQS6
SRRLRLEPLVLQMSS	LENG8	521	Q96PV6
NRLPIATRSRSRTNM	GAPVD1	476	Q14C86
TSSNRELLRITVPNM	CFAP52	361	Q8N1V2
RLMRLDSFLERPSTS	KIF3C	741	O14782
QLLLMVARRTQSETP	PCNX2	771	A6NKB5
ARPSEALQDTLRRMQ	PNMA6F	391	A0A0J9YX94
LPRARAERTVMRQDN	MLH3	1111	Q9UHC1
ESLRPRSQLMLTRKA	KANSL1	336	Q7Z3B3
STSSLPLAALNMRVR	MYD88	16	Q99836
ASLDLQRMIRTSPNS	GLI2	241	P10070
MDRTRFPDVLRNQSL	LRRC63	51	Q05C16
MQSREDVPRSRRLAS	KBTBD7	1	Q8WVZ9
RRLAVNRSPVAMTRS	LAMA5	3666	O15230
LRRSQMSPQGLRVRL	ITGB4	96	P16144
TPRVQRLNELEAMTR	KDM5A	71	P29375
DTVLAPLRMSQVRSL	MEI1	1091	Q5TIA1
SIALLPRNRDKNRSM	PTPRU	1196	Q92729
MTAAIRRQRELSILP	P2RY13	1	Q9BPV8
RKQSRLDPSSAVLMR	RIMS1	471	Q86UR5
TCISRQRVLPRMQAR	MYO15B	351	Q96JP2
IRVPLRSSMLTRNSR	CCSER2	261	Q9H7U1
RSSMLTRNSRQPEVL	CCSER2	266	Q9H7U1
ICTIRSRRPQMVRSV	ATM	2606	Q13315
MAPSLKELRVLSNRR	ICE2	36	Q659A1
MQSPAVLVTSRRLQN	HS1BP3	1	Q53T59
IDRKSQTMPALRNRS	DOCK11	1346	Q5JSL3
RMDPRRRQAALSFLT	CABLES1	56	Q8TDN4
TLASNERIPLNRTMR	DNAH17	2226	Q9UFH2
FTLRPQTLRQRMAEE	GCFC2	191	P16383
PSRAARQLMERTQSS	ELMO2	81	Q96JJ3
SRAPTTTMRNLVERL	CEP290	1716	O15078
MNSVRAANRRPRRVS	FBXO11	1	Q86XK2
PIAARLQMSERSILS	CHD3	1891	Q12873
RSLQTLRDIQRMLFP	BCL9	361	O00512
TQRRMAPERVASLSR	FANCC	171	Q00597
PRRVEMANLLNLSER	HOXB3	216	P14651
SMTQLLRRRRAVLPQ	ADAM9	196	Q13443
IRLLNVRTPTLRTSM	DENND5A	611	Q6IQ26
TLRMRQIASNTSLQR	MAP3K20	576	Q9NYL2
MSLQSRLSGRLAQLR	MACROD1	1	Q9BQ69
LNSMVSKLQEDPRRR	MAN2A2	196	P49641
FSMVSLLVNSPRVRV	MAN2A2	661	P49641
RLSQATRQRLSIPVM	TMEM259	221	Q4ZIN3
MQGTSRSLRLIQDRV	LAMB3	1001	Q13751
ATRQPSMTLQRAVSL	DLG2	401	Q15700
LVAENSRSTQRLMLP	LIG1	381	P18858
ISPRLRSRFNIINMT	DNAH2	2541	Q9P225
AIRRASTIEMPQQAR	PLN	11	P26678
AMVIDSRNSSILPRR	SAMM50	261	Q9Y512
PQGLATLETRQMNRR	RNF41	256	Q9H4P4
PDIRQRMSNQRSITT	MEP1B	506	Q16820
NARRRILQPMLDASN	PKNOX2	341	Q96KN3
ARQRLISLMSGELQR	C2CD5	191	Q86YS7
SEQIRIPRITSMDAR	CNTN3	986	Q9P232
MQSREDAPRSRRLAS	KBTBD6	1	Q86V97
MTSNTILSADRPSRL	MED1	1546	Q15648
VLVMLAAQSRRSVPL	TBRG4	261	Q969Z0
RRSFQSLRLLCTQMP	MTMR3	356	Q13615
RMVSRRTFQPLSQSL	PTCD2	371	Q8WV60
PTIMTRRLCTNLVVN	OR11G2	171	Q8NGC1
RMNTIPQTRSIQSRF	PARP6	541	Q2NL67
NMSVTRSNSLRRDSP	PAK4	91	O96013
PRDVQARMLSSTTIL	PTPRD	421	P23468
NPSFLRQALRRNTML	KBTBD12	226	Q3ZCT8
AQRQRARERQESLMP	OSBPL5	676	Q9H0X9
RRRIVQPMIDQSNRT	MEIS3P1	216	A6NDR6
MRELLALVPQRATSS	PKP1	416	Q13835
TSQRELFPRLTADMR	SZT2	3196	Q5T011
LAMSKSRNPRLQTAA	HSF2BP	306	O75031
QLERRESSLPALMTT	USH2A	1501	O75445
LEELRRNMRSQPLTS	UTRN	1391	P46939
QRTLSQMSHRLEPRR	RAPGEF4	996	Q8WZA2
DQTTRRSPYRMSRIL	STARD13	31	Q9Y3M8
RSLRPNRQLGSMVEI	TRIM39	76	Q9HCM9
PRSLRGLQMILNSDR	TCAIM	361	Q8N3R3
RLMRQSRRSTQGVTL	PPP1R12C	551	Q9BZL4
LSPLQSMAAQRQRAL	PUF60	111	Q9UHX1
PSTRVMRNLTQAARE	TMEM255A	151	Q5JRV8
PMVTQSDLRSVRLRS	NHSL2	821	Q5HYW2
INARRRILQPMLDSS	PKNOX1	311	P55347
LSSTNDSPRQMRKLV	RIPPLY1	61	Q0D2K3
TRPMDLQTLRENVRK	TAF1L	1441	Q8IZX4
LQSQMPSIRLIFRRL	OR5AU1	6	Q8NGC0
MQSFRRPSAASIDLR	PRAM1	466	Q96QH2
LRRQAFLRSVSMPAE	RHBDF1	41	Q96CC6
NDPNLRQRAMSRASI	SCN9A	681	Q15858
TAQRPARQNLRDLVM	SOWAHC	196	Q53LP3
SSRKQPMSATLRERL	SFR1	41	Q86XK3
RELEALRQAMRTPSR	RHPN1	146	Q8TCX5
RENSSPRVMQRKQSL	DLC1	1241	Q96QB1
QRLAPLLSTSMTSER	ADGRD2	496	Q7Z7M1
LRNNRTTEVPRLDSM	ARAP1	716	Q96P48
TRRSFRPNLQLANMV	TRIM52	191	Q96A61
RSEIIMSPATLRRQI	XIRP2	3036	A4UGR9
ISMLEQRRDPRNLQS	ZNF880	56	Q6PDB4
MAVRPKERSSLSSRQ	WWC2	976	Q6AWC2
APQTARIRTRMQNDS	TOR1AIP1	291	Q5JTV8
RIFSALRVLPDTMRN	RNF112	481	Q9ULX5
IAKSINRNSVRSRMP	RIPOR3	36	Q96MK2
MRSEDPRSVINLLRN	RPEL1	201	Q2QD12
EIRRERERQTNPSAM	VCP	706	P55072
VLLTLRPRRINMTDT	SAGE1	221	Q9NXZ1
RRVMEPLTASRLQVR	PPAN	51	Q9NQ55
TLQSRLIMRNQGSLR	RANBP3L	336	Q86VV4
PSLTLRNFLSRNRLM	TLCD3A	106	Q8TBR7
RRLQVEMSSQQFPRL	SAP130	21	Q9H0E3
DLLMRESTENVPRTR	NPY	76	P01303
METRQVSRSPRVRLL	PTH2	1	Q96A98
STALLRTLPRASLMR	nan	41	Q9UF83
SSQNPLIMRRRVRSF	TCF20	1246	Q9UGU0
MENDPSRRRESISLT	SLC28A1	1	O00337
MSTLRDLIFKRPSRQ	SYMPK	696	Q92797
MVEISRTQPLTRREQ	TTC38	96	Q5R3I4
RPFRNVSRQTSRQMS	USP24	1271	Q9UPU5
MQRAETRASANAPRR	PLEKHG2	831	Q9H7P9
MRSEDPRSVINLLRN	RPE	201	Q96AT9
VRVSMQLRRPSDREL	RELA	266	Q04206
VAPAAMLSSRQRRLS	WNK4	1176	Q96J92
RLTNPVSRFMQVRSL	SOCS6	486	O14544
RMETTPSKALRSRLQ	ZBTB34	181	Q8NCN2
DMLRSLATTRPTVNA	VPS4A	406	Q9UN37
RQEMQTPRTRPRLSA	KLHL29	566	Q96CT2
RPISDRFLMRVNESS	LMX1B	61	O60663
NLMRLEEQLSPRSRV	MYT1L	381	Q9UL68