Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium ion binding

DCHS2 PCDHA9 SYT9 ADGRV1 STAB1 ESYT2 FAT1 DST SYT13 HSPG2 FAT4 DSG2 PCDHGA11 PCDHGA6 FAT3 PCLO PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1 MACF1 PCDHGA8 CDH15

5.38e-0674925926GO:0005509
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

DCHS2 PCDHA9 FAT1 NECTIN4 FAT4 SDK2 DSCAM DSG2 PCDHGA11 PCDHGA6 FAT3 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1 PCDHGA8 CDH15

2.39e-1318725720GO:0007156
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

DCHS2 PCDHA9 FAT1 NECTIN4 FAT4 SDK2 DSCAM DSG2 PCDHGA11 PCDHGA6 FAT3 PCDHA13 PCDHA11 PCDHA8 PCDHA6 GRID2 PCDHA4 PCDHA2 PCDHA1 PCDHGA8 CDH15

4.44e-1031325721GO:0098742
GeneOntologyBiologicalProcesscell-cell adhesion

DCHS2 PCDHA9 ADGRV1 ITGAV FAT1 NECTIN4 TLN2 FAT4 SDK2 DSCAM DSG2 PCDHGA11 KIF26B PCDHGA6 FAT3 CAMSAP3 ITGA10 LAMA3 PCDHA13 PCDHA11 PCDHA8 GPAM PCDHA6 GRID2 PCDHA4 PCDHA2 PCDHA1 SIGLEC1 PCDHGA8 CDH15

3.28e-05107725730GO:0098609
MousePhenoincreased spleen germinal center number

C4A C4B C5AR1 BANK1 PLD4 RGS13 BECN1

4.36e-08261927MP:0008481
MousePhenoabnormal macrophage cell number

AKR1A1 KMT2E LYST C3 C4A ADGRF5 C4B C5AR1 PLD4 HSPG2 LAMA3 IL18BP RIOX2 DCLRE1C

3.02e-0527819214MP:0020202
DomainCadherin_CS

DCHS2 PCDHA9 FAT1 FAT4 DSG2 PCDHGA11 PCDHGA6 FAT3 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1 PCDHGA8 CDH15

1.17e-1310925417IPR020894
DomainCADHERIN_1

DCHS2 PCDHA9 FAT1 FAT4 DSG2 PCDHGA11 PCDHGA6 FAT3 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1 PCDHGA8 CDH15

2.15e-1311325417PS00232
DomainCadherin

DCHS2 PCDHA9 FAT1 FAT4 DSG2 PCDHGA11 PCDHGA6 FAT3 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1 PCDHGA8 CDH15

2.15e-1311325417PF00028
Domain-

DCHS2 PCDHA9 FAT1 FAT4 DSG2 PCDHGA11 PCDHGA6 FAT3 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1 PCDHGA8 CDH15

2.50e-13114254172.60.40.60
DomainCADHERIN_2

DCHS2 PCDHA9 FAT1 FAT4 DSG2 PCDHGA11 PCDHGA6 FAT3 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1 PCDHGA8 CDH15

2.50e-1311425417PS50268
DomainCA

DCHS2 PCDHA9 FAT1 FAT4 DSG2 PCDHGA11 PCDHGA6 FAT3 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1 PCDHGA8 CDH15

2.90e-1311525417SM00112
DomainCadherin-like

DCHS2 PCDHA9 FAT1 FAT4 DSG2 PCDHGA11 PCDHGA6 FAT3 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1 PCDHGA8 CDH15

3.36e-1311625417IPR015919
DomainCadherin

DCHS2 PCDHA9 FAT1 FAT4 DSG2 PCDHGA11 PCDHGA6 FAT3 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1 PCDHGA8 CDH15

4.48e-1311825417IPR002126
DomainCadherin_tail

PCDHA9 PCDHGA11 PCDHGA6 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1 PCDHGA8

1.48e-123725411PF15974
DomainCadherin_CBD

PCDHA9 PCDHGA11 PCDHGA6 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1 PCDHGA8

1.48e-123725411IPR031904
DomainCadherin_2

PCDHA9 PCDHGA11 PCDHGA6 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1 PCDHGA8

1.11e-096525411PF08266
DomainCadherin_N

PCDHA9 PCDHGA11 PCDHGA6 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1 PCDHGA8

1.11e-096525411IPR013164
DomainDEP_dom

DVL1P1 RAPGEF3 DVL1 PIKFYVE FMN2 DEPDC5

4.96e-07232546IPR000591
DomainDEP

DVL1P1 RAPGEF3 DVL1 PIKFYVE DEPDC5

9.75e-06222545PF00610
DomainDEP

DVL1P1 RAPGEF3 DVL1 PIKFYVE DEPDC5

9.75e-06222545PS50186
DomainDEP

DVL1P1 RAPGEF3 DVL1 PIKFYVE DEPDC5

9.75e-06222545SM00049
DomainAnaphylatoxn_comp_syst_dom

C3 C4A C4B

2.44e-0552543IPR001840
DomainAnaphylatoxin_comp_syst

C3 C4A C4B

2.44e-0552543IPR018081
DomainLamG

FAT1 HSPG2 FAT4 FAT3 LAMA3 COL18A1

2.73e-05442546SM00282
DomainARM-type_fold

GPRASP1 TRRAP LYST PI4KA PUM3 GCN1 UNC79 DOCK1 ZYG11A RANBP6 APOB HEATR5A RALGAPA2 PPP4R3B DAAM2

6.67e-0533925415IPR016024
DomainANATO

C3 C4A C4B

8.36e-0572543SM00104
DomainANAPHYLATOXIN_2

C3 C4A C4B

8.36e-0572543PS01178
DomainANAPHYLATOXIN_1

C3 C4A C4B

8.36e-0572543PS01177
DomainAnaphylatoxin/fibulin

C3 C4A C4B

8.36e-0572543IPR000020
DomainANATO

C3 C4A C4B

8.36e-0572543PF01821
DomainMacrogloblnA2_thiol-ester-bond

C3 C4A C4B

1.32e-0482543IPR019565
DomainThiol-ester_cl

C3 C4A C4B

1.32e-0482543PF10569
DomainMacrogloblnA2_CS

C3 C4A C4B

1.32e-0482543IPR019742
DomainLaminin_G

FAT1 HSPG2 FAT4 FAT3 LAMA3 COL18A1

1.34e-04582546IPR001791
DomainLAM_G_DOMAIN

FAT1 HSPG2 FAT4 FAT3 LAMA3

1.56e-04382545PS50025
DomainDVL-1

DVL1P1 DVL1

1.84e-0422542IPR008340
DomainLaminin_G_2

FAT1 HSPG2 FAT4 FAT3 LAMA3

1.99e-04402545PF02210
DomainConA-like_dom

ADGRV1 TRIM14 ADGRG4 FAT1 PTPRK HSPG2 TRIM15 FAT4 FAT3 LAMA3 COL18A1

2.13e-0421925411IPR013320
DomainSpectrin

DST SYNE2 SYNE1 MACF1

2.41e-04232544PF00435
DomainACTININ_2

DST SYNE2 SYNE1 MACF1

2.41e-04232544PS00020
DomainACTININ_1

DST SYNE2 SYNE1 MACF1

2.41e-04232544PS00019
DomainActinin_actin-bd_CS

DST SYNE2 SYNE1 MACF1

2.41e-04232544IPR001589
DomainA2M

C3 C4A C4B

2.78e-04102543PF00207
DomainA2M_N_2

C3 C4A C4B

2.78e-04102543IPR011625
DomainA2M_comp

C3 C4A C4B

2.78e-04102543IPR011626
DomainA2M_recep

C3 C4A C4B

2.78e-04102543PF07677
DomainA2M_comp

C3 C4A C4B

2.78e-04102543PF07678
DomainA2M_N_2

C3 C4A C4B

2.78e-04102543PF07703
DomainA2M_N

C3 C4A C4B

2.78e-04102543PF01835
DomainA2M_N

C3 C4A C4B

2.78e-04102543IPR002890
DomainA-macroglobulin_rcpt-bd

C3 C4A C4B

2.78e-04102543IPR009048
DomainALPHA_2_MACROGLOBULIN

C3 C4A C4B

2.78e-04102543PS00477
DomainMacroglobln_a2

C3 C4A C4B

2.78e-04102543IPR001599
Domain-

ADGRV1 ADGRG4 FAT1 HSPG2 FAT4 FAT3 LAMA3

3.16e-049525472.60.120.200
DomainSpectrin_repeat

DST SYNE2 SYNE1 MACF1

6.07e-04292544IPR002017
DomainEGF_LAM_2

STAB1 HSPG2 LAMA3 LAMB2

6.93e-04302544PS50027
DomainEGF_LAM_1

STAB1 HSPG2 LAMA3 LAMB2

6.93e-04302544PS01248
DomainATPase_dyneun-rel_AAA

MDN1 DNAH6 DYNC1H1

8.10e-04142543IPR011704
DomainAAA_5

MDN1 DNAH6 DYNC1H1

8.10e-04142543PF07728
DomainSEA

ADGRF5 HSPG2 MUC16

8.10e-04142543SM00200
DomainSPEC

DST SYNE2 SYNE1 MACF1

8.90e-04322544SM00150
DomainSpectrin/alpha-actinin

DST SYNE2 SYNE1 MACF1

8.90e-04322544IPR018159
DomainLactamase_B

ELAC2 DCLRE1C ETHE1

1.00e-03152543SM00849
DomainKASH

SYNE2 SYNE1

1.09e-0342542PS51049
DomainDishevelled

DVL1P1 DVL1

1.09e-0342542PF02377
DomainLactamase_B_2

ELAC2 DCLRE1C

1.09e-0342542PF12706
DomainKASH

SYNE2 SYNE1

1.09e-0342542PF10541
DomainDishevelled_fam

DVL1P1 DVL1

1.09e-0342542IPR008339
Domain-

C3 C4A

1.09e-03425421.20.91.20
DomainKASH

SYNE2 SYNE1

1.09e-0342542IPR012315
DomainKASH

SYNE2 SYNE1

1.09e-0342542SM01249
DomainDishevelled_protein_dom

DVL1P1 DVL1

1.09e-0342542IPR003351
DomainEGF_Lam

STAB1 HSPG2 LAMA3 LAMB2

1.26e-03352544SM00180
DomainLaminin_EGF

STAB1 HSPG2 LAMA3 LAMB2

1.26e-03352544PF00053
DomainC345C

C3 C4A C4B

1.47e-03172543SM00643
DomainLaminin_EGF

STAB1 HSPG2 LAMA3 LAMB2

1.71e-03382544IPR002049
DomainTerpenoid_cyclase/PrenylTrfase

C3 C4A C4B

1.74e-03182543IPR008930
DomainTMEM132D_N

TMEM132B TMEM132C

1.79e-0352542PF15705
DomainTMEM132D_C

TMEM132B TMEM132C

1.79e-0352542PF15706
DomainVmron_rcpt_1

VN1R3 VN1R4

1.79e-0352542IPR004072
DomainTMEM132

TMEM132B TMEM132C

1.79e-0352542IPR026307
DomainTMEM132_M

TMEM132B TMEM132C

1.79e-0352542IPR031437
DomainTMEM132_C

TMEM132B TMEM132C

1.79e-0352542IPR031436
DomainTMEM132_N

TMEM132B TMEM132C

1.79e-0352542IPR031435
DomainBPI/LBP

PLTP BPIFB2

1.79e-0352542IPR030675
DomainCOUP_TF

HNF4A NR2F2

1.79e-0352542IPR003068
DomainV1R

VN1R3 VN1R4

1.79e-0352542PF03402
DomainTMEM132

TMEM132B TMEM132C

1.79e-0352542PF16070
DomainNTR

C3 C4A C4B

2.05e-03192543PF01759
DomainNetrin_module_non-TIMP

C3 C4A C4B

2.05e-03192543IPR018933
Domain-

ELAC2 DCLRE1C ETHE1

2.39e-032025433.60.15.10
DomainMetallo-B-lactamas

ELAC2 DCLRE1C ETHE1

2.39e-03202543IPR001279
DomainCadherin_C

PCDHA9 PCDHGA11 PCDHGA6 PCDHGA8

2.49e-03422544IPR032455
DomainCadherin_C_2

PCDHA9 PCDHGA11 PCDHGA6 PCDHGA8

2.49e-03422544PF16492
DomainCH

DST SYNE2 SYNE1 CAMSAP3 MACF1

2.64e-03702545PF00307
DomainGAR

DST MACF1

2.67e-0362542PS51460
DomainMyb-like_dom

DMTF1 EP400

2.67e-0362542IPR017877
DomainGAS_dom

DST MACF1

2.67e-0362542IPR003108
Domain-

DST MACF1

2.67e-03625423.90.1290.10
DomainGAS2

DST MACF1

2.67e-0362542PF02187
Domain-

DST MACF1

2.67e-03625423.30.920.20
DomainGAS2

DST MACF1

2.67e-0362542SM00243
Domain-

GALK2 LONP2 TOP2A

2.76e-032125433.30.230.10
Pubmed

Interaction with protocadherin-gamma regulates the cell surface expression of protocadherin-alpha.

PCDHA9 PCDHGA11 PCDHGA6 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1

6.23e-15282641015347688
Pubmed

Monoallelic yet combinatorial expression of variable exons of the protocadherin-alpha gene cluster in single neurons.

PCDHA9 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1

6.09e-1415264815640798
Pubmed

Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice.

PCDHA9 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1

2.27e-1317264829911975
Pubmed

CNR/Pcdhalpha family in subplate neurons, and developing cortical connectivity.

PCDHA9 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1

4.06e-1318264815570159
Pubmed

Genomic organization of the family of CNR cadherin genes in mice and humans.

PCDHA9 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1

4.06e-1318264810662547
Pubmed

Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.

PCDHA9 PCDHGA11 PCDHGA6 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1 PCDHGA8

4.09e-12682641111230163
Pubmed

Developmental epigenetic modification regulates stochastic expression of clustered protocadherin genes, generating single neuron diversity.

PCDHA9 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1

6.56e-1224264824698270
Pubmed

A striking organization of a large family of human neural cadherin-like cell adhesion genes.

PCDHA9 PCDHGA11 PCDHGA6 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1 PCDHGA8

7.86e-12722641110380929
Pubmed

Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.

PCDHA9 PCDHGA11 PCDHGA6 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1 PCDHGA8

1.07e-11742641110817752
Pubmed

Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.

PCDHA9 PCDHGA11 PCDHGA6 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1 PCDHGA8

1.68e-11772641110835267
Pubmed

Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.

PCDHA9 PCDHGA11 PCDHGA6 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1

1.69e-11572641032633719
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ACACA MYO7A CC2D1A PIGG TRRAP BIRC6 LYST ELAC2 ADCY7 FAT1 DST MDN1 KCNG1 PI4KA TLN2 GCN1 TTC38 DYNC1H1 AGAP3 HSPG2 EP400 DVL1 LAMB2 SMG5 RALGAPA2 NR2F2 KANSL3 PIKFYVE FANCI ZFYVE26 DEPDC5 TNFAIP2 SLC45A1

2.42e-1111052643335748872
Pubmed

Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.

PCDHA9 PCDHGA11 PCDHGA6 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1 PCDHGA8

2.58e-11802641110716726
Pubmed

Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex.

PCDHA9 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4

8.09e-111126469655502
Pubmed

Proteins of the CNR family are multiple receptors for Reelin.

PCDHA9 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4

1.61e-1012264610612399
Pubmed

The DNA sequence and comparative analysis of human chromosome 5.

PCDHA9 CCNO RBM27 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1

2.88e-10752641015372022
Pubmed

CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons.

PCDHA9 PCDHGA6 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1

5.62e-1058264930377227
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

ADGRV1 BIRC6 STAB1 ESYT2 DST SYNE2 TLN2 CAMTA1 GCN1 SYNE1 ALS2 CHD7 SMG5 MACF1

2.33e-092252641412168954
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

UBAP2 ADGRV1 STAB1 DST INTS2 RBM27 MED23 SYT13 SDK2 PDCD6IP SASH1 EP400 PHRF1 ZNF507 KIAA1549 SMG5 KANSL3 PPP4R3B TET1 DEPDC5

5.32e-095292642014621295
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

UBAP2 ACACA MYO9A CC2D1A LYST ESYT2 DST MDN1 PI4KA SYNE2 KIF11 AGAP3 PDCD6IP SASH1 DSG2 KIF26B NCKIPSD CAMSAP3 ALS2 RESF1 TET1 FMN2 MACF1 BECN1 OTOG

1.28e-088612642536931259
Pubmed

A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220.

PCDHA9 PCDHGA11 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1 SLC26A7

2.76e-081192641028625976
Pubmed

Modulation of the antitumor immune response by complement.

C3 C4A C4B C5AR1

4.81e-086264418820683
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TCAF1 KIAA0586 MRPS27 TRIM14 BIRC6 ATAD3C KCNS2 PUM3 ADGRF5 NUP160 CEP290 ARHGEF18 GPAM TRAPPC8 RALGAPA2 PIKFYVE ZNF526 MACF1

5.35e-084932641815368895
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

ACACA MYO7A LRRC70 BIRC6 TMEM132B DST MDN1 KCNG1 PI4KA KCNS2 BANK1 DYNC1H1 FAT4 MXRA5 KIF26B PCLO CEP290 CAMSAP3 GPAM RIOX2 FMN2 MTMR9

6.02e-087362642229676528
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PCDHA9 MDN1 TLN2 DYNC1H1 ADAMTS3 CEP290 DAAM2 ZFYVE26 PCDHGA8

1.07e-0710426499205841
Pubmed

Expression of mouse dchs1, fjx1, and fat-j suggests conservation of the planar cell polarity pathway identified in Drosophila.

DCHS2 FAT1 FAT4 FAT3

1.12e-077264416059920
Pubmed

Complement C3a signaling facilitates skeletal muscle regeneration by regulating monocyte function and trafficking.

C3 C4A C4B C5AR1

1.12e-077264429233958
Pubmed

Synergy between the classical and alternative pathways of complement is essential for conferring effective protection against the pandemic influenza A(H1N1) 2009 virus infection.

C3 C4A C4B C5AR1

2.22e-078264428301559
Pubmed

Genetic polymorphism of murine C3 controlled by a single co-dominant locus on chromosome 17.

C3 C4A C4B

4.32e-0732643681746
Pubmed

Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity.

C3 C4A C4B

4.32e-07326438524789
Pubmed

Immune complex glomerulonephritis in C4- and C3-deficient mice.

C3 C4A C4B

4.32e-07326439461092
Pubmed

Regulation of the B cell response to T-dependent antigens by classical pathway complement.

C3 C4A C4B

4.32e-07326438752901
Pubmed

Complement genes contribute sex-biased vulnerability in diverse disorders.

C3 C4A C4B

4.32e-073264332499649
Pubmed

Role of complement in a murine model of peanut-induced anaphylaxis.

C3 C4A C4B

4.32e-073264323182714
Pubmed

Serum complement component 3, complement component 4 and complement component 1q levels predict progressive visual field loss in older women with primary angle closure glaucoma.

C3 C4A C4B

4.32e-073264335017157
Pubmed

Genetic evidence for involvement of classical complement pathway in induction of experimental autoimmune myasthenia gravis.

C3 C4A C4B

4.32e-073264314500686
Pubmed

In vitro C3 deposition on Cryptococcus capsule occurs via multiple complement activation pathways.

C3 C4A C4B

4.32e-073264321723612
Pubmed

Acute nephrotoxic serum nephritis in complement knockout mice: relative roles of the classical and alternate pathways in neutrophil recruitment and proteinuria.

C3 C4A C4B

4.32e-07326439829481
Pubmed

Three distinct profiles of serum complement C4 proteins in pediatric systemic lupus erythematosus (SLE) patients: tight associations of complement C4 and C3 protein levels in SLE but not in healthy subjects.

C3 C4A C4B

4.32e-073264316893076
Pubmed

Complement C4-deficient mice have a high mortality rate during PTZ-induced epileptic seizures, which correlates with cognitive problems and the deficiency in the expression of Egr1 and other immediate early genes.

C3 C4A C4B

4.32e-073264337234916
Pubmed

Epithelial secretion of C3 promotes colonization of the upper urinary tract by Escherichia coli.

C3 C4A C4B

4.32e-073264311433344
Pubmed

Increased susceptibility to endotoxin shock in complement C3- and C4-deficient mice is corrected by C1 inhibitor replacement.

C3 C4A C4B

4.32e-07326439218619
Pubmed

Complement Inhibitor CRIg/FH Ameliorates Renal Ischemia Reperfusion Injury via Activation of PI3K/AKT Signaling.

C3 C4A C4B C5AR1

6.58e-0710264430429287
Pubmed

Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.

DMTF1 FAT4 SYNE1 PCLO

1.03e-0611264420351715
Pubmed

Impaired mast cell-dependent natural immunity in complement C3-deficient mice.

C3 C4A C4B

1.72e-06426439367154
Pubmed

Complement C4 is protective for lupus disease independent of C3.

C3 C4A C4B

1.72e-064264311801636
Pubmed

A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo.

C3 C4A C4B

1.72e-064264310934224
Pubmed

The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74).

C3 C4A C5AR1

1.72e-064264311773063
Pubmed

Intestinal reperfusion injury is mediated by IgM and complement.

C3 C4A C4B

1.72e-064264310066708
Pubmed

Antigen localization within the splenic marginal zone restores humoral immune response and IgG class switch in complement C4-deficient mice.

C3 C4A C4B

1.72e-064264315477230
Pubmed

Phylogeny of the C3/C4/C5 complement-component gene family indicates that C5 diverged first.

C3 C4A C4B

1.72e-06426438015436
Pubmed

The alternative activation pathway and complement component C3 are critical for a protective immune response against Pseudomonas aeruginosa in a murine model of pneumonia.

C3 C4A C4B

1.72e-064264315102802
Pubmed

Macrophages from C3-deficient mice have impaired potency to stimulate alloreactive T cells.

C3 C4A C4B

1.72e-064264316304047
Pubmed

Efficient amyloid A clearance in the absence of immunoglobulins and complement factors.

C3 C4A C4B

1.72e-064264323454183
Pubmed

The human complement system: assembly of the classical pathway C3 convertase.

C3 C4A C4B

1.72e-06426436906228
Pubmed

Functional analysis of Ficolin-3 mediated complement activation.

C3 C4A C4B

1.72e-064264321085669
Pubmed

Protection against anti-glomerular basement membrane (GBM)-mediated nephritis in C3- and C4-deficient mice.

C3 C4A C4B

1.72e-06426439409643
Pubmed

Complement Activation Contributes to Severe Acute Respiratory Syndrome Coronavirus Pathogenesis.

C3 C4A C4B

1.72e-064264330301856
Pubmed

Allelic distribution of complement components BF, C4A, C4B, and C3 in Psoriasis vulgaris.

C3 C4A C4B

1.72e-064264311803045
Pubmed

Complement classical pathway components are all important in clearance of apoptotic and secondary necrotic cells.

C3 C4A C4B

1.72e-064264319302245
Pubmed

Evidence for non-traditional activation of complement factor C3 during murine liver regeneration.

C3 C4A C4B

1.72e-064264318452991
Pubmed

Blocking properdin, the alternative pathway, and anaphylatoxin receptors ameliorates renal ischemia-reperfusion injury in decay-accelerating factor and CD59 double-knockout mice.

C3 C4A C4B C5AR1

2.20e-0613264423427256
Pubmed

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

AZU1 CC2D1A AKR1A1 ITGAV NECTIN4 C3 C4A C4B TTC38 DYNC1H1 HSPG2 COL6A3 FAT4 PDCD6IP LAMA3 LAMB2 APOB IL18BP COL18A1 CUTA SERPINC1 BPIFB2 TNXA CDH15

2.61e-0610702642423533145
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

RBM27 UNC79 SYT13 MUC20 PDCD6IP HEATR5A CHD7 KANSL3 PPP4R3B

2.81e-06153264910718198
Pubmed

The C5a receptor on mast cells is critical for the autoimmune skin-blistering disease bullous pemphigoid.

C4A C4B C5AR1

4.28e-065264321393236
Pubmed

The generation of thymus-independent germinal centers depends on CD40 but not on CD154, the T cell-derived CD40-ligand.

C3 C4A C4B

4.28e-065264316783845
Pubmed

Local production and activation of complement up-regulates the allostimulatory function of dendritic cells through C3a-C3aR interaction.

C3 C4A C4B

4.28e-065264318056835
Pubmed

Complement proteins C3 and C4 bind to collagen and elastin in the vascular wall: a potential role in vascular stiffness and atherosclerosis.

C3 C4A C4B

4.28e-065264321707943
Pubmed

Role of complement receptors 1 and 2 (CD35 and CD21), C3, C4, and C5 in survival by mice of Staphylococcus aureus bacteremia.

C3 C4A C4B

4.28e-065264315192652
Pubmed

A role for Mac-1 (CDIIb/CD18) in immune complex-stimulated neutrophil function in vivo: Mac-1 deficiency abrogates sustained Fcgamma receptor-dependent neutrophil adhesion and complement-dependent proteinuria in acute glomerulonephritis.

C3 C4A C4B

4.28e-06526439382884
Pubmed

Protective T cell-independent antiviral antibody responses are dependent on complement.

C3 C4A C4B

4.28e-065264310523614
Pubmed

Stromal complement receptor CD21/35 facilitates lymphoid prion colonization and pathogenesis.

C3 C4A C4B

4.28e-065264317947689
Pubmed

The C5 convertase is not required for activation of the terminal complement pathway in murine experimental cerebral malaria.

C3 C4A C4B

4.28e-065264322689574
Pubmed

Predominant role for C5b-9 in renal ischemia/reperfusion injury.

C3 C4A C4B

4.28e-065264310811844
Pubmed

Intranasal peptide-induced tolerance and linked suppression: consequences of complement deficiency.

C3 C4A C4B

4.28e-065264325039245
Pubmed

Both complement and IgG fc receptors are required for development of attenuated antiglomerular basement membrane nephritis in mice.

C3 C4A C4B

4.28e-065264319710463
Pubmed

The complete exon-intron structure of a human complement component C4A gene. DNA sequences, polymorphism, and linkage to the 21-hydroxylase gene.

C4A C4B TNXA

4.28e-06526431988494
Pubmed

Classical and alternative complement activation on photoreceptor outer segments drives monocyte-dependent retinal atrophy.

C3 C4A C4B

4.28e-065264329743491
Pubmed

Formation of high affinity C5 convertase of the classical pathway of complement.

C3 C4A C4B

4.28e-065264312878586
Pubmed

Complement C4A Regulates Autoreactive B Cells in Murine Lupus.

C3 C4A C4B

4.28e-065264333147456
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

ACACA BIRC6 DST GCN1 KIF11 CAMSAP3 ZNF507 DVL1 CHD7 RLF NOL4L RESF1 WDCP TET1

4.50e-064182641434709266
Pubmed

A human MAP kinase interactome.

MYO9A PARD6B DST C4A GCN1 DOCK1 PDCD6IP KIF26B CCDC186 SYNE1 CEP290 LAMA3 LAMB2 PIAS1 MACF1

5.51e-064862641520936779
Pubmed

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

KIAA0586 C8orf34 FAT1 MDN1 SYNE2 SEPTIN1 UNC79 MUC16 OTOG

6.65e-06170264923314748
Pubmed

Cross-Linking Mass Spectrometry Uncovers Interactions Between High-Density Lipoproteins and the SARS-CoV-2 Spike Glycoprotein.

C3 C4A C4B DYNC1H1 APOB COL18A1 SERPINC1

6.78e-0692264737343697
Pubmed

Predominant role of IgM-dependent activation of the classical pathway in the clearance of dying cells by murine bone marrow-derived macrophages in vitro.

C3 C4A C4B

8.50e-066264315597324
Pubmed

Ubiquitin-SUMO circuitry controls activated fanconi anemia ID complex dosage in response to DNA damage.

FANCD2 PIAS1 FANCI

8.50e-066264325557546
Pubmed

CD21/35 promotes protective immunity to Streptococcus pneumoniae through a complement-independent but CD19-dependent pathway that regulates PD-1 expression.

C3 C4A C4B

8.50e-066264319710450
Pubmed

Burn injury reveals altered phenotype in mannan-binding lectin-deficient mice.

C3 C4A C4B

8.50e-066264317363917
Pubmed

Fancd2-deficient hematopoietic stem and progenitor cells depend on augmented mitochondrial translation for survival and proliferation.

FANCD2 ATAD3C FANCI

8.50e-066264331472450
Pubmed

Structure and genetics of the partially duplicated gene RP located immediately upstream of the complement C4A and the C4B genes in the HLA class III region. Molecular cloning, exon-intron structure, composite retroposon, and breakpoint of gene duplication.

C4A C4B TNXA

8.50e-06626438132574
Pubmed

A dominant complement fixation pathway for pneumococcal polysaccharides initiated by SIGN-R1 interacting with C1q.

C3 C4A C4B

8.50e-066264316615889
Pubmed

A physical interaction network of dengue virus and human proteins.

DST PDCD6IP APOB PIAS1

9.13e-0618264421911577
Pubmed

Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.

HSPG2 COL6A3 ADAMTS3 LAMB2 APOB COL18A1

9.37e-0664264622261194
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

BIRC6 ESYT2 INTS2 MED23 SYNE1 RALGAPA2 MACF1

1.43e-05103264710574462
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

TRRAP DST SYNE2 DNAH6 NUP160 KIF11 COL6A3 MXRA5 SYNE1

1.43e-05187264926460568
Pubmed

Functional interactions between Fat family cadherins in tissue morphogenesis and planar polarity.

FAT1 FAT4 FAT3

1.48e-057264322510986
Pubmed

Complement component C3 binds to activated normal platelets without preceding proteolytic activation and promotes binding to complement receptor 1.

C3 C4A C4B

1.48e-057264320139276
Pubmed

A platelet-mediated system for shuttling blood-borne bacteria to CD8α+ dendritic cells depends on glycoprotein GPIb and complement C3.

C3 C4A C4B

1.48e-057264322037602
Pubmed

Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome.

C4A C4B C5AR1

1.48e-057264314660741
Pubmed

Protection from Streptococcus pneumoniae infection by C-reactive protein and natural antibody requires complement but not Fc gamma receptors.

C3 C4A C4B

1.48e-057264312055255
InteractionPCDHA10 interactions

PCDHA9 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2

6.57e-09222537int:PCDHA10
InteractionFLT3 interactions

PCDHA9 TRRAP MDN1 PI4KA PUM3 GCN1 DYNC1H1 PCDHGA11 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 APOB PCDHA1 SLC26A7 FANCI

1.22e-0731825318int:FLT3
InteractionPCDHA9 interactions

PCDHA9 PCDHGA11 LONP2 PCDHGA6 PCDHA11 PCDHA4

2.54e-06322536int:PCDHA9
InteractionCEACAM8 interactions

ADGRV1 ITGAV FAT1 PTPRK MANEAL PLTP FAT4 SDK2 LAMA3 KIAA1549

2.61e-0611925310int:CEACAM8
InteractionPCDHA1 interactions

PCDHA11 PCDHA8 PCDHA4 PCDHA1

2.91e-0692534int:PCDHA1
InteractionPCDHA11 interactions

PCDHA9 LONP2 PCDHA11 PCDHA4 PCDHA1

3.02e-06192535int:PCDHA11
InteractionPCDHA3 interactions

PCDHA9 LONP2 PCDHA11 PCDHA8 PCDHA6 PCDHA1

3.70e-06342536int:PCDHA3
InteractionSLAMF1 interactions

ADGRV1 FAT1 INTS2 LAMA3 LAMB2 NR2F2 RGS13 FANCI TNFAIP2 BECN1

4.08e-0612525310int:SLAMF1
InteractionPCDHA8 interactions

LONP2 PCDHA13 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1

5.49e-06552537int:PCDHA8
InteractionPCDHA7 interactions

PCDHA9 PCDHA8 PCDHA4 PCDHA2

2.20e-05142534int:PCDHA7
InteractionCD160 interactions

ADGRV1 ITGAV FAT1 PTPRK FAT4 FAT3

2.91e-05482536int:CD160
InteractionTOP3B interactions

UBAP2 ACACA MYO7A CC2D1A PIGG TRRAP BIRC6 LYST ELAC2 ADCY7 FAT1 DST MDN1 KCNG1 PI4KA TLN2 GCN1 TTC38 DYNC1H1 AGAP3 HSPG2 PDCD6IP EP400 DVL1 LAMB2 APOB SMG5 RALGAPA2 NR2F2 KANSL3 PIKFYVE FANCI ZFYVE26 DEPDC5 TNFAIP2 SLC45A1 MRPL11

3.93e-05147025337int:TOP3B
InteractionTAFA5 interactions

ADGRV1 PLTP FAT4 SDK2

6.46e-05182534int:TAFA5
InteractionRYK interactions

DVL1P1 DST PTPRK DYNC1H1 FAT4 SDK2 DSG2 PCDHGA11 PCDHGA6 FAT3 DVL1

8.00e-0521225311int:RYK
InteractionPCDHGA10 interactions

PCDHA9 PCDHA11 PCDHA8 PCDHA4

8.10e-05192534int:PCDHGA10
InteractionDCANP1 interactions

FAT1 FAT4 PCDHGA11 FAT3

8.10e-05192534int:DCANP1
Cytoband5q31

PCDHA9 SLC4A9 PCDHGA11 PCDHGA6 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1 PCDHGA8

3.71e-12115264125q31
CytobandEnsembl 112 genes in cytogenetic band chr5q31

PCDHA9 SLC4A9 PCDHGA11 PCDHGA6 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1 PCDHGA8

1.95e-0729826412chr5q31
GeneFamilyClustered protocadherins

PCDHA9 PCDHGA11 PCDHGA6 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1 PCDHGA8

3.30e-11641801120
GeneFamilyCadherin related

DCHS2 FAT1 FAT4 FAT3

2.04e-0517180424
GeneFamilyC3 and PZP like, alpha-2-macroglobulin domain containing

C3 C4A C4B

7.80e-05918031234
GeneFamilyImmunoglobulin like domain containing

HEPACAM PTPRK ADGRF5 HSPG2 SDK2 MXRA5 DSCAM IL18BP CD96

1.39e-041931809594
GeneFamilyComplement system|Sushi domain containing

C3 C4A C4B C5AR1

4.36e-04361804492
GeneFamilySpectrin repeat containing nuclear envelope family

SYNE2 SYNE1

5.84e-04418021252
GeneFamilyEndogenous ligands|Minor histocompatibility antigens

PUM3 TYMP RESF1 LY75

1.65e-03511804870
GeneFamilyEF-hand domain containing|Plakins

DST MACF1

2.65e-0381802939
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages|lymph-node_spleen / Manually curated celltypes from each tissue

PDK4 STAB1 DST C5AR1 PLTP SASH1 DSCAM TYMP DAAM2 SIGLEC1 TNFAIP2

1.09e-08180263117be7d7a6906fff6dbdecd9cb013d855aba4eda2a
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRV1 FAT1 TLN2 UNC79 FAT4 KIF26B FAT3 PCLO APOB GRIK3 OTOG

1.37e-08184263112cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRV1 FAT1 TLN2 UNC79 FAT4 KIF26B FAT3 PCLO APOB GRIK3 OTOG

1.37e-08184263112b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRV1 FAT1 TLN2 UNC79 FAT4 KIF26B FAT3 PCLO APOB GRIK3 OTOG

1.37e-0818426311ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CTNNAL1 BIRC6 DST SYNE2 TOX3 ADGRF5 FAT4 CHD7 RALGAPA2 RESF1 MACF1

3.24e-0820026311dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO9A SYT9 PARD6B HSPG2 DPP6 LAMA3 HEATR5A GRIK3 LRRC1 DAAM2

1.07e-07177263109af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ACACA MYO9A ADGRV1 C8orf34 PARD6B SLC9C1 PTPRK ADGRF5 SYNE1 LAMA3

2.64e-07195263109406866f99555198a9be311fbd65751b70f35446
ToppCellLPS_only-Unknown-Endothelial-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HMGCS2 LIN7A SLC9C1 SLCO1C1 TRPV1 PYROXD2 ITGA10 GRIK3

4.23e-071152638c67145d3cd9243994a141749b426ff2a6dcc8d93
ToppCellLPS_only-Unknown-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HMGCS2 LIN7A SLC9C1 SLCO1C1 TRPV1 PYROXD2 ITGA10 GRIK3

4.23e-071152638ad5298c2ad8bf94fa13c2e50b0799e929473ef59
ToppCellLPS_only-Unknown|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HMGCS2 LIN7A SLC9C1 SLCO1C1 TRPV1 PYROXD2 ITGA10 GRIK3

4.23e-0711526387a733f6987b40ec497a03734b79ed5355ad3a2fc
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SYNE2 UGT2A1 ATG9B EID2 IL18BP NOL4L RESF1 GZMK PCDHGA8

6.62e-0716626399e916fc1858573358e1eb5e3789b2c9f8ef74476
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DST ACSM5 TLN2 COL6A3 FAT4 ITGA10 PODN MACF1 DAAM2

1.03e-0617526391799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DDX59 CC2D1A TMEM132B MDN1 MUC20 FAT3 LAMB2 TNFAIP2 MTMR9

1.03e-061752639dbd9dac129fb6ae5f55e7b96d04b37585458dc4a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PLEKHS1 STAP1 LIN7A ADGRF5 SLC4A9 ADAMTS3 C4orf54 SLC26A7 GYG1

1.08e-061762639cb21342dd135cc80a50aafe7bf8bf31265db68dd
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLEKHS1 STAP1 LIN7A TOX3 ADGRF5 SLC4A9 DSCAM DSG2 SLC26A7

1.13e-0617726398e4005fad50e6f919da175f3b9ae58849dbd60b1
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GPRASP1 RBM27 COL6A3 PCDHGA6 FAT3 PCDHA4 TET1 DAAM2 CATSPERB

1.18e-06178263909475e522dc1b8cf9ff1c25de5d1e3082b162948
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GPRASP1 RBM27 COL6A3 PCDHGA6 FAT3 PCDHA4 TET1 DAAM2 CATSPERB

1.18e-061782639000d25f3f13cc76cf39c46c312c6fafc2ea4f368
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GPRASP1 RBM27 COL6A3 PCDHGA6 FAT3 PCDHA4 TET1 DAAM2 CATSPERB

1.18e-06178263935de8f791b0e78a6caf52ff095f05e204a59e828
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

DCHS2 MYO9A FAT1 RAPGEF3 SYNE2 DPP6 ADAMTS3 KIF26B FMN2

1.18e-061782639544379f5a6145429762258d426b876bb36c112f5
ToppCell390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|390C / Donor, Lineage, Cell class and subclass (all cells)

DCHS2 CCNO PLEKHS1 TOX3 NECTIN4 MUC16 GRIK3 BPIFB2 TNFAIP2

1.18e-061782639fce60ce6b662f1bdaa3b4da43800c6c22fe89533
ToppCell390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|390C / Donor, Lineage, Cell class and subclass (all cells)

DCHS2 CCNO PLEKHS1 TOX3 NECTIN4 MUC16 GRIK3 BPIFB2 TNFAIP2

1.18e-061782639b19c906e067b07eadfd68934d9330b447e24c708
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCX LIN7A PARD6B NECTIN4 OLFM1 KIF26B PCLO CHD7 CDH15

1.78e-0618726391b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
ToppCellCOVID-19-Epithelial-Ionocytes|COVID-19 / Condition, Lineage and Cell class

CCNO STAP1 SLC9C1 FAT1 ADGRF5 C4B MUC20 HSPG2 MUC16

1.86e-061882639a581cb9528d0febbf3addbb4f6bc140f91a584e6
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYT9 HMGCS2 STAP1 LIN7A ESYT2 SLC9C1 TOX3 SLC4A9 SLC26A7

1.95e-061892639532aaf02b364c5c4f58a2021c7c21d86df3875c9
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMEM132B LIN7A TMEM132C FAT1 COL6A3 SYNE1 GRID2 NR2F2 DAAM2

2.12e-06191263908042952431ca1a6fd7dfc13f36eb28643979598
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADGRG4 STAT4 TMEM132C SYNE2 TTC38 SYNE1 GZMK MACF1 CD96

2.21e-061922639ce867b6e78c1d8f30dff81bf572a78a897bc7625
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADGRG4 STAT4 TMEM132C SYNE2 TTC38 SYNE1 GZMK MACF1 CD96

2.21e-06192263958a7829b411b02b422ef75e2277a868969cc23e8
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW10-Myeloid|GW10 / Sample Type, Dataset, Time_group, and Cell type.

RGSL1 PDK4 C19orf84 C3 C5AR1 PLD4 C12orf71 DAAM2 MRNIP

2.41e-0619426394f28841c7f37884fc34c6689cd6976c6559d23f1
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SPATA33 KCNS2 UNC79 SLC4A9 SYT13 FAT3 MUC16 FMN2 PCSK4

2.41e-0619426392dcc3b99dbedaf8a6916891c85091ddb79d7ee31
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW10-Myeloid-Microglia|GW10 / Sample Type, Dataset, Time_group, and Cell type.

RGSL1 PDK4 C19orf84 C3 C5AR1 PLD4 C12orf71 DAAM2 MRNIP

2.41e-061942639459e836bcdb6742333684ac23d960efa5e99702f
ToppCellCOVID_non-vent-Lymphocytic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

KMT2E STAT4 SYNE2 SEPTIN1 SYNE1 ZNF507 RESF1 MACF1 CD96

2.74e-061972639c672915f8c8c1e948d251f6eaf9f84a5600c1193
ToppCellTransverse-B_cell-B_cell_IgG_Plasma|B_cell / Region, Cell class and subclass

PARD6B ESYT2 KHDC1L TOX3 COL6A3 PYROXD2 KIAA1549 MUC16 HEATR5A

2.74e-061972639a0a096e8e80763a92d5d7396eb678a4587771a3a
ToppCell10x3'2.3-week_14-16-Endothelial-stroma-sinusoidal_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PDK4 TMEM132B STAB1 ADGRF5 PLTP HSPG2 SASH1 DSG2 NR2F2

2.74e-061972639f1080d93acf1a4756d2f2c8cabd1fb50bc7bcd09
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CTNNAL1 STAT4 SYNE2 KIF11 SYNE1 FANCI GZMK TOP2A CD96

2.85e-06198263980b105a7c7d00ea3b5e586831fbb755bd84f9d1a
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CTNNAL1 STAT4 SYNE2 KIF11 SYNE1 FANCI GZMK TOP2A CD96

2.85e-061982639c73e906d2d12d6eba0e606958be16e63a2292cd0
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_macrophage|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MYO7A PDK4 STAB1 C5AR1 PLTP SASH1 DAAM2 SIGLEC1 TNFAIP2

2.97e-061992639b827dd8a249f904a0ff930a6c4d3b00fb7bc6fb1
ToppCell3'_v3-GI_small-bowel-Myeloid_Mac-Intestinal_macrophages|GI_small-bowel / Manually curated celltypes from each tissue

PDK4 STAB1 DST C5AR1 PLTP PLD4 SASH1 SIGLEC1 TNFAIP2

2.97e-06199263996070b5ffcbab4952970f43b536969ddd2ca5d14
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

TCAF1 TMEM132C FAT1 DST COL6A3 FAT4 NR2F2 PODN DAAM2

2.97e-06199263938cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCell3'_v3-GI_small-bowel-Myeloid_Mac|GI_small-bowel / Manually curated celltypes from each tissue

PDK4 STAB1 DST C5AR1 PLTP PLD4 SASH1 SIGLEC1 TNFAIP2

2.97e-0619926398990a3d69e24cb3aaba9d6def3d0be9ee973436d
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_macrophage-macrophage|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MYO7A PDK4 STAB1 C5AR1 PLTP SASH1 DAAM2 SIGLEC1 TNFAIP2

2.97e-061992639c0dcdda30485bb920d3706dcfb06f11b76b6ea37
ToppCellControl-Control-Myeloid-immature_Neutrophil|Control / Disease, condition lineage and cell class

AZU1 LIN7A FANCD2 KIF11 CHD7 RLF KANSL3 CIAO3 TOP2A

3.10e-062002639118321ac443feb42aee171baccfc4610f00a8822
ToppCellmLN-Macrophage|mLN / Region, Cell class and subclass

MYO7A PDK4 STAB1 C5AR1 PLTP SASH1 CDCP1 SIGLEC1 TNFAIP2

3.10e-06200263968d709afd226241e002dae6d6820bccd1cfd87a1
ToppCellLPS_IL1RA-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CTNNAL1 DST SYNE2 ADGRF5 DYNC1H1 SASH1 RALGAPA2 RESF1 MACF1

3.10e-0620026395c092b2ecc081b5d04476c56333c338cd89ab984
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DCHS2 AHCYL1 ADGRV1 SLCO1C1 RAPGEF3 SASH1 SYNE1 GPAM MACF1

3.10e-062002639d0812817ef99608994193787a62d39adeb2070ca
ToppCell10x5'v1-week_14-16-Endothelial-stroma-sinusoidal_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PDK4 TMEM132B STAB1 ADGRF5 PLTP HSPG2 SASH1 DSG2 NR2F2

3.10e-062002639ae429f2de652cc1976e63644781197e9ce0e70c8
ToppCellLPS_IL1RA-Endothelial-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CTNNAL1 DST SYNE2 ADGRF5 DYNC1H1 SASH1 RALGAPA2 RESF1 MACF1

3.10e-06200263972ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCellmLN-(6)_Macrophage|mLN / shred on region, Cell_type, and subtype

MYO7A PDK4 STAB1 C5AR1 PLTP SASH1 CDCP1 SIGLEC1 TNFAIP2

3.10e-0620026396dcba82a7d322102bae205543086e84c7655b3e0
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DCHS2 AHCYL1 ADGRV1 SLCO1C1 RAPGEF3 SASH1 SYNE1 GPAM MACF1

3.10e-062002639cd54ddf1919c98e84b7e4aba85b374fc8b407206
ToppCellLPS-antiTNF-Endothelial-Epi-like-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACACA STAP1 RMC1 DNAH6 TTC38 PDIK1L LRRC1 MRNIP

3.15e-0615026389cb3332924bd67c966873343c14445e30d3f384f
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-9|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NIBAN3 STAP1 DBNDD1 PTPRK KCNG1 BANK1 C12orf71 SDK2

3.31e-0615126382314c004434aed9b7fa1ad01c61c43e5ed4a18ce
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Rorb-Excitatory_Neuron.Sc17a7.Rorb-Gpr83_(Layer_5a)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

KLHL41 SCX STAT4 CDCP1 C4orf54 RGS13 GZMK

3.63e-0610826375af010a1ee6535b144ccd16999c225508a4b3433
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2-Npnt_(Retrosplenial_areas,_layer_5,_Npnt+)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SLURP2 ARHGEF18 APOB CBY2 BPIFB2

4.15e-06412635b1e70962de91a747ec718a3fad4247fd0cb7d9a8
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2-Npnt_(Retrosplenial_areas,_layer_5,_Npnt+)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SLURP2 ARHGEF18 APOB CBY2 BPIFB2

4.15e-0641263516dbb13baa47c4db80ddd83ac36aad6c43b5461a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PLEKHS1 STAP1 LIN7A TOX3 ADGRF5 SLC4A9 C4orf54 SLC26A7

4.63e-061582638debebc8534a80e5500051f6fd352dc201585968d
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAP1 FOXRED2 DPEP3 OLFM1 PLTP SASH1 ARHGEF18 SIGLEC1

4.85e-061592638323cb4a2416d2e6bff0a3f225d2edeae9ab7dc76
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLEKHS1 STAP1 LIN7A ADGRF5 SLC4A9 SDK2 DSG2 SLC26A7

5.08e-061602638174a4ab27114efcc63be36929b80680be3c35c9b
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLEKHS1 STAP1 ADGRF5 SLC4A9 MUC20 DSG2 TMEM31 SLC26A7

6.38e-061652638a6c6de17fec678ad0cac3138dde3a14cc39ffd26
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Cerebellum / BrainAtlas - Mouse McCarroll V32

ANKRD13B DBNDD1 KCNS2 UNC79 ADAMTS3 GRIK3 SLC45A1 EPHA8

6.97e-0616726389efb9511a211d0824bb97f82c1a5860c43d2138f
ToppCellCerebellum-Neuronal-Inhibitory|Cerebellum / BrainAtlas - Mouse McCarroll V32

ANKRD13B DBNDD1 KCNS2 UNC79 ADAMTS3 GRIK3 SLC45A1 EPHA8

6.97e-061672638904c613aac3f9919a432b110bb1dcc832b5aec0a
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CTNNAL1 TMEM132B SDK2 PCDHA11 GRID2 PCDHA2 GRIK3 CHD7

6.97e-06167263817c653b46507c8bb85da95836ae72a6015336142
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLEKHS1 HMGCS2 TOX3 ADGRF5 SLC4A9 KLB DSG2 SLC26A7

6.97e-061672638166b7b4ca0663cde6d88219ee0bcc1988d03dab8
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OLFM1 TLN2 C5AR1 SYNE1 RESF1 ETHE1 LY75 TOP2A

7.28e-061682638faaba5ac01c2ebe380f56559374a121979a85a13
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CTNNAL1 TMEM132B DST DBNDD1 PCDHA1 GRIK3 CHD7 COL18A1

7.28e-061682638af82e07d1eec51fc6530155f37addbce6221885d
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NIBAN3 STAT4 ADAMTS3 DSG2 LAMA3 CDCP1 CDH15

7.71e-06121263705c40fd39e6b6275f35aaad835f95a81fcbb0990
ToppCellfacs-Marrow-T_cells-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCNO SYNE2 C3 C5AR1 KIF11 SYNE1 ETHE1 LY75

8.28e-06171263895e87987a2332fa646849fb0de785f1e0b8a07dd
ToppCellfacs-Marrow-T_cells-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCNO SYNE2 C3 C5AR1 KIF11 SYNE1 ETHE1 LY75

8.28e-06171263836657e277aad75c4f157c1726c48e09b5836cf37
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-5_VIP_KCNJ2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TOX3 FAT4 SDK2 MXRA5 GRID2 CHD7 NR2F2 NR2E1

9.41e-061742638fdadac1eaab2c4a67e4832f0901df22e893add6a
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_3|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CCNO PLEKHS1 NECTIN4 MUC20 KIF26B PCLO MUC16 CDCP1

9.41e-0617426389e5fae9ecc7c0111fc8a252e72b89dc89c0d3a7c
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE2 C3 C5AR1 KIF11 SYNE1 ETHE1 LY75 TOP2A

1.11e-05178263815a99080e9f669572ab6d82934f324e6714846c1
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE2 C3 C5AR1 KIF11 SYNE1 ETHE1 LY75 TOP2A

1.11e-051782638200308e109abb7e6f8816a6f8cce6d56862d4098
ToppCellCOVID-19-kidney-Epi_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

DCHS2 DST C3 ADAMTS3 KIF26B SYNE1 LAMA3 NR2F2

1.16e-051792638e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO9A SYT9 PARD6B HSPG2 DPP6 LAMA3 HEATR5A LRRC1

1.25e-051812638b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellfacs-Marrow-B-cells-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE2 C3 C5AR1 KIF11 SYNE1 ETHE1 LY75 TOP2A

1.30e-051822638c075756cd4bb484ede1be2bcdb9eac60eab0573a
ToppCellfacs-Marrow-B-cells-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE2 C3 C5AR1 KIF11 SYNE1 ETHE1 LY75 TOP2A

1.30e-0518226389025178ede571e3808d4657ad4892152f336c9b4
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DCHS2 SLC7A13 FTCD ADGRV1 DNAJC22 HNF4A UGT2A1 TRPV1

1.36e-051832638d73cac83cde82665f110baad7cf28db75f9ffe52
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ACACA HMGCS2 ADGRV1 C8orf34 FAT1 PTPRK TOX3 NECTIN4

1.41e-051842638102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCellpdx-Tumor_cells-T0|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

HMGCS2 FTCD HNF4A PTPRK TOX3 KLB GPAM COL18A1

1.47e-0518526381d874608aa2062024323512f68889219471b2f00
ToppCellCOPD-Epithelial-Goblet|World / Disease state, Lineage and Cell class

CCNO PLEKHS1 PARD6B FAT1 PTPRK TOX3 MUC16 CATSPERB

1.53e-051862638d75fe7640a4b2c450c9759a1b3c3ef2a087f0092
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ADGRV1 STAB1 PCLO LAMA3 MUC16 DAAM2 TNFAIP2 HDAC10

1.53e-05186263823b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellSubstantia_nigra-Neuronal-Inhibitory|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

DBNDD1 CAMTA1 UNC79 SYT13 KIF26B CAMSAP3 OGDH SLC45A1

1.53e-0518626389d3efe2a4feea2bc205a7e45b9b9f9ed9b3609ce
ToppCellLPS_only-Myeloid-Dendritic_cells-pDC|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNF280B NIBAN3 PLD4 TRPV1 SIGLEC1 CDH15 MTMR9

1.58e-0513526370afe232aa1a1e6c37a5b3183b67d7fa07e0ea791
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO9A SYT9 ADGRV1 SYNE2 C3 DPP6 SDK2 LAMA3

1.59e-05187263858d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

TMEM132C DST TLN2 COL6A3 FAT4 FAT3 PODN DAAM2

1.59e-051872638bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCDHA9 HMGCS2 TMEM132C C3 C4B HSPG2 COL6A3 PODN

1.65e-051882638b382d18fb09fb2869f3c151efa71540a7f5ed229
ToppCellnormal_Lymph_Node-Myeloid_cells-mo-Mac|normal_Lymph_Node / Location, Cell class and cell subclass

PDK4 STAB1 DST C5AR1 PLTP SASH1 SIGLEC1 TNFAIP2

1.65e-051882638e83de94a9b47a6a90e98face887eae031a322af6
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDK4 HEPACAM KAT2B SLCO1C1 RAPGEF3 DOCK1 CHD7 DAAM2

1.65e-051882638505b6b4277d7dea87aee27191d0acca67928b8e6
ToppCellHealthy-B_naive|World / disease group, cell group and cell class

NIBAN3 SCX STAP1 DBNDD1 PTPRK KCNG1 RAPGEF3 BANK1

1.71e-0518926381e533a43f739ff295740cf2b25479756dfb8e595
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LIN7A TMEM132C FAT1 COL6A3 SYNE1 GRID2 NR2F2 DAAM2

1.71e-0518926387ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

STAT4 SYNE2 TTC38 DMTF1 SYNE1 RESF1 MACF1 CD96

1.78e-051902638d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCellSevere-Lymphoid-T-NK|Severe / Condition, Lineage, Cell class and cell subclass

STAT4 SYNE2 SEPTIN1 KIF11 FANCI GZMK TOP2A CD96

1.78e-05190263860642de433f84fa2cecd796c3a1a4aab9219d3db
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CTNNAL1 MYO7A STAB1 C12orf71 SASH1 NR2F2 COL18A1 LRRC1

1.78e-05190263826e2237f65cb43723c5da853831b40df2982d6e4
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HMGCS2 STAP1 TOX3 ADGRF5 SLC4A9 MUC20 DSG2 SLC26A7

1.78e-051902638223587b5df037794a2cee234babf87d12bf48ac8
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CTNNAL1 MYO7A STAB1 C12orf71 SASH1 NR2F2 COL18A1 LRRC1

1.78e-051902638a1514d2186eb4fe569971ab22dc0c17d353fb94a
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CTNNAL1 MYO7A STAB1 C12orf71 SASH1 NR2F2 COL18A1 LRRC1

1.78e-0519026380bb954a94317cfc742b9b6221bb80f8baa6d3ff1
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDK4 HEPACAM SLCO1C1 RAPGEF3 C3 DOCK1 CHD7 DAAM2

1.85e-051912638a90c8ab2077e52bbc998457c85a1b9867f9c8c93
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF280B HEPACAM SYNE2 TTC38 SYNE1 NOL4L GZMK CD96

1.92e-05192263897c312c82ec025c13052f8d424b11c0034c8ea54
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TCAF1 TMEM132C FAT1 TOX3 COL6A3 FAT4 FAT3 NR2F2

1.92e-05192263872881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCellPND28-Mesenchymal-Mesenchymal_structural|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMEM132C C3 C4B COL6A3 NR2F2 GYG1 PODN MACF1

1.99e-051932638ec81c1afdae2e0433a22c8c1fa1c6232526ff7e7
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMEM132C C3 C4B COL6A3 NR2F2 GYG1 PODN MACF1

1.99e-05193263830481fb01c7acf85beae10213f038da86bed6777
ToppCellsevere_influenza-B_naive|severe_influenza / disease group, cell group and cell class (v2)

NIBAN3 STAP1 DBNDD1 PTPRK BANK1 PLD4 SDK2 CHD7

2.07e-0519426387c1e9ce5de3bb1657a67010de673c8bb60129cb6
Disease1,5 anhydroglucitol measurement

PCDHA9 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1

9.91e-11292548EFO_0008009
Diseasevisceral adipose tissue measurement, body mass index

PCDHA9 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1

8.78e-07872548EFO_0004340, EFO_0004765
Diseaseneutrophil count, basophil count

PCDHA9 HNF4A NUP160 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1 CHD7

4.30e-0622425411EFO_0004833, EFO_0005090
Diseaseneuroticism measurement, cognitive function measurement

PCDHA9 NUP210L BIRC6 STAB1 PTPRK RMC1 DSCAM PCLO ZNF507 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1 GRIK3

9.56e-0656625417EFO_0007660, EFO_0008354
Diseasephospholipids:total lipids ratio, intermediate density lipoprotein measurement

HNF4A BANK1 PLTP GPAM APOB MACF1

2.47e-05672546EFO_0008595, EFO_0020946
Disease1-stearoylglycerol 1-monostearin measurement

SYNE2 KIAA1549

7.38e-0522542EFO_0021111
Diseasepost-traumatic stress disorder symptom measurement

SYNE1 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1

7.77e-05822546EFO_0008535
Diseasesystemic lupus erythematosus (is_implicated_in)

STAT4 C3 C4A C4B BANK1

1.97e-04622545DOID:9074 (is_implicated_in)
DiseaseHennekam syndrome (is_implicated_in)

FAT4 ADAMTS3

2.20e-0432542DOID:0060366 (is_implicated_in)
DiseaseHennekam lymphangiectasia-lymphedema syndrome

FAT4 ADAMTS3

2.20e-0432542C0340834
Diseasecholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement

HNF4A SYNE2 BANK1 GPAM APOB MACF1

2.73e-041032546EFO_0008595, EFO_0020944
Diseasecortical thickness

ANKRD13B GALK2 NUP210L ADGRV1 ELAC2 STAB1 PI4KA TOX3 DLEC1 CAMTA1 BANK1 AGAP3 HSPG2 ADAMTS3 FAT3 CHD7 NR2F2 COL18A1 NOL4L CBY2 FMN2 MACF1

2.75e-04111325422EFO_0004840
Diseasehair colour measurement

ADGRV1 LYST SPATA33 DBNDD1 RBM27 SYNE2 TOX3 SASH1 MTERF1 RANBP6 FMN2 CATSPERB BPIFB2 SLC45A1 CDH15

3.16e-0461525415EFO_0007822
DiseaseLupus Erythematosus, Systemic

STAT4 C4A C4B BANK1 PHRF1

3.72e-04712545C0024141
Diseasepost-traumatic stress disorder

KAT2B KHDC1L DPP6 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1

3.85e-042022548EFO_0001358
Diseasephospholipids in large HDL measurement

HNF4A BANK1 PLTP GPAM APOB

4.24e-04732545EFO_0022190
DiseaseAutosomal dominant Emery-Dreifuss muscular dystrophy

SYNE2 SYNE1

4.38e-0442542cv:CN293514
DiseaseX-22162 measurement

TTC38 PYROXD2

4.38e-0442542EFO_0800839
DiseaseUsher Syndrome

MYO7A PLD4

4.38e-0442542C0271097
Diseasefree cholesterol to total lipids in large LDL percentage

BANK1 PLTP GPAM APOB MACF1

4.51e-04742545EFO_0022280
Diseasevital capacity

PCDHA9 MFSD6 KMT2E C8orf34 DST RMC1 AGAP3 HSPG2 COL6A3 ADAMTS3 SYNE1 PCLO PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 APOB PCDHA1 CHD7 PDIK1L OTOG

4.67e-04123625423EFO_0004312
Diseasesystemic lupus erythematosus (implicated_via_orthology)

C4A C4B PLD4 BECN1

5.08e-04432544DOID:9074 (implicated_via_orthology)
Diseasewhite matter microstructure measurement

ANKRD13B SPATA33 BANK1 SLC4A9 SDK2 SASH1 APOB PCDHA1 XRCC4 CARF CATSPERB

6.13e-0439025411EFO_0005674
Diseasecholesterol:total lipids ratio, intermediate density lipoprotein measurement

HNF4A SYNE2 BANK1 GPAM APOB MACF1

6.46e-041212546EFO_0008595, EFO_0020943
DiseaseAutosomal Recessive Emery-Dreifuss Muscular Dystrophy

SYNE2 SYNE1

7.26e-0452542C1450051
DiseaseAutosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)

SYNE2 SYNE1

7.26e-0452542C0410190
DiseaseDiGeorge syndrome (is_implicated_in)

DVL1P1 DVL1

7.26e-0452542DOID:11198 (is_implicated_in)
DiseaseHypoplastic Left Heart Syndrome

PCDHA9 PCDHA13

7.26e-0452542C0152101
DiseaseAbnormality of refraction

PCDHA9 BIRC6 DPEP3 DLEC1 DSCAM FAT3 PCLO PHRF1 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 PCDHA1

7.98e-0467325415HP_0000539
Diseasethalamus volume

ADGRV1 CAMTA1 DPP6 FAT3 MACF1

8.51e-04852545EFO_0006935
Diseasecholesteryl esters to total lipids in IDL percentage

BANK1 GPAM APOB MACF1

9.05e-04502544EFO_0022247
DiseaseImmunologic Deficiency Syndromes

C3 C4A CHD7

9.83e-04232543C0021051
Diseasepulse pressure measurement

PCDHA9 MRPS27 AKR1A1 UGT2A1 TLN2 DLEC1 NUP160 KLB COL6A3 MXRA5 DSCAM MTERF1 FAT3 PCDHA13 PCDHA11 PCDHA8 PCDHA6 PCDHA4 PCDHA2 HEATR5A PCDHA1 SLC26A7 TET1 LRRC1

1.02e-03139225424EFO_0005763
DiseaseEmery-Dreifuss muscular dystrophy

SYNE2 SYNE1

1.08e-0362542cv:C0410189
DiseaseMuscular Dystrophy, Emery-Dreifuss

SYNE2 SYNE1

1.08e-0362542C0410189
Diseasecongenital muscular dystrophy (implicated_via_orthology)

DYNC1H1 COL6A3

1.08e-0362542DOID:0050557 (implicated_via_orthology)
DiseaseBehcet Syndrome

STAT4 C4A APOB

1.12e-03242543C0004943
Diseasenephrotic syndrome (biomarker_via_orthology)

GPAM APOB SERPINC1

1.12e-03242543DOID:1184 (biomarker_via_orthology)
DiseaseSquamous cell carcinoma of esophagus

FAT1 DLEC1 FAT4 FAT3 TYMP

1.40e-03952545C0279626
DiseaseN6-methyllysine measurement

PYROXD2 GPAM

1.51e-0372542EFO_0800061
DiseaseX-Linked Emery-Dreifuss Muscular Dystrophy

SYNE2 SYNE1

1.51e-0372542C0751337
Diseasecholesterol:total lipids ratio, low density lipoprotein cholesterol measurement

HNF4A SYNE2 PLTP APOB OGDH MACF1

1.59e-031442546EFO_0004611, EFO_0020943
Diseaseneurodegenerative disease (implicated_via_orthology)

DVL1P1 DYNC1H1 FAT4 DVL1 GRIK3 OGDH

1.65e-031452546DOID:1289 (implicated_via_orthology)
Diseasecholesterol to total lipids in IDL percentage

BANK1 GPAM APOB MACF1

1.79e-03602544EFO_0022233
Diseasefree cholesterol to total lipids in medium HDL percentage

HNF4A PLTP GPAM APOB

1.79e-03602544EFO_0022282
Diseasefree cholesterol in HDL measurement

HNF4A PLTP GPAM APOB

1.90e-03612544EFO_0022264
Diseasephospholipids in HDL measurement

HNF4A PLTP GPAM APOB

1.90e-03612544EFO_0022293
Diseasehippocampus volume change measurement, age at assessment

TMEM132C MOCS3 KCNG1

1.95e-03292543EFO_0008007, EFO_0021492
Diseasecommon bile duct neoplasm (is_marker_for)

APOB TYMP

2.00e-0382542DOID:4608 (is_marker_for)
Diseaseribose-5-phosphate measurement, ribulose-5-phosphate measurement

TMEM132C GRID2

2.00e-0382542EFO_0010529, EFO_0010530
Diseaseneutrophil count

PCDHA9 NUP210L KMT2E HNF4A OLFM1 TLN2 ADGRF5 RMC1 ZNF282 NUP160 C12orf71 DSCAM PCDHA13 PCDHA11 PCDHA8 GPAM PCDHA6 PCDHA4 PCDHA2 PCDHA1 CHD7 MRNIP LY75

2.04e-03138225423EFO_0004833
Diseasetotal lipids in HDL measurement

HNF4A PLTP GPAM APOB

2.15e-03632544EFO_0022307
Diseaselipoprotein measurement

HNF4A PLTP DOCK1 GPAM APOB

2.18e-031052545EFO_0004732
Diseaseunipolar depression, bipolar disorder

SYNE2 DMTF1 FAT4 SYNE1 PCLO GRIK3

2.38e-031562546EFO_0003761, MONDO_0004985
Diseasetotal lipids in very large HDL measurement

BANK1 PLTP GPAM APOB

2.54e-03662544EFO_0022312
Diseasephospholipids in very large HDL measurement

BANK1 PLTP GPAM APOB

2.54e-03662544EFO_0022298
DiseaseRNA-binding protein 24 measurement

C3 PIKFYVE

2.55e-0392542EFO_0802030
DiseaseX-21467 measurement

SLCO1C1 MTERF1

2.55e-0392542EFO_0020007
Diseaseobesity (implicated_via_orthology)

DCHS2 HNF4A STAT4 C3 C5AR1 FAT4 SDK2

2.71e-032152547DOID:9970 (implicated_via_orthology)
DiseaseBenign Neoplasm

PLEKHS1 BIRC6 TRPV1 ATF2

2.84e-03682544C0086692
DiseaseNeoplasms

PLEKHS1 BIRC6 TRPV1 ATF2

2.84e-03682544C0027651
Diseasetriglycerides to phosphoglycerides ratio

BANK1 PLTP GPAM APOB

2.84e-03682544EFO_0022327
DiseaseComplement deficiency disease

C3 C4A C4B

2.84e-03332543C0272242
Diseasecholesterol in very large HDL measurement

BANK1 PLTP GPAM APOB

2.99e-03692544EFO_0022229
DiseaseAlzheimer disease, age at onset

DCHS2 AHCYL1 TMEM132C FAT1 DST PUM3 BANK1 HSPG2 COL18A1

3.06e-033432549EFO_0004847, MONDO_0004975
DiseaseDNA-directed RNA polymerases I and III subunit RPAC1 measurement

C3 PIKFYVE

3.17e-03102542EFO_0801535
DiseaseOCIA domain-containing protein 1 measurement

C3 PIKFYVE

3.17e-03102542EFO_0008252
Diseasediabetes mellitus biomarker

KIF11 GRID2

3.17e-03102542EFO_0006842
Diseasethrombosis (implicated_via_orthology)

C5AR1 SERPINC1

3.17e-03102542DOID:0060903 (implicated_via_orthology)
Diseasecancer antigen 125 measurement

MUC16 CIAO3

3.17e-03102542EFO_0010603
DiseaseFanconi anemia (is_implicated_in)

FANCD2 FANCI

3.17e-03102542DOID:13636 (is_implicated_in)
Diseasechildhood trauma measurement, alcohol consumption measurement

C8orf34 PCDHGA11 PCDHGA6 PCDHGA8

3.32e-03712544EFO_0007878, EFO_0007979
Diseasehigh density lipoprotein particle size measurement

AHCYL1 HNF4A BANK1 PLTP GPAM APOB

3.64e-031702546EFO_0008592
Diseasetotal lipids in large HDL

BANK1 PLTP GPAM APOB

3.85e-03742544EFO_0022189
Diseasecytochrome p450 3a4 measurement

APOB PIKFYVE

3.86e-03112542EFO_0020303
Diseasediffuse scleroderma (is_implicated_in)

STAT4 BANK1

3.86e-03112542DOID:1580 (is_implicated_in)
DiseaseSodium measurement

DVL1 PRDM12

3.86e-03112542C0337443
DiseaseAdverse Event by CTCAE Category

DVL1 PRDM12

3.86e-03112542C1879645
Diseasenucleus accumbens volume change measurement

DSCAM MUC16

3.86e-03112542EFO_0021493
Diseasevery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

HNF4A SYNE2 BANK1 PLTP GPAM APOB MACF1 MTMR9

3.89e-032912548EFO_0008317, EFO_0020946
DiseaseEmery-Dreifuss muscular dystrophy (implicated_via_orthology)

SYNE2 SYNE1

4.60e-03122542DOID:11726 (implicated_via_orthology)
Diseaseamyloid plaque accumulation rate

MOCS3 KCNG1

4.60e-03122542EFO_0007646
Diseasefree cholesterol in large HDL measurement

BANK1 PLTP GPAM APOB

4.86e-03792544EFO_0022157
Diseasetriglycerides:total lipids ratio, intermediate density lipoprotein measurement

HNF4A SYNE2 GPAM APOB MACF1

4.93e-031272545EFO_0008595, EFO_0020947
Diseasecholesterol in large HDL measurement

BANK1 PLTP GPAM APOB

5.08e-03802544EFO_0021900
Diseasephospholipids:total lipids ratio, high density lipoprotein cholesterol measurement

AHCYL1 HNF4A BANK1 PLTP GPAM APOB MACF1 CDH15

5.34e-033072548EFO_0004612, EFO_0020946
Diseasehyperglycemia (is_marker_for)

ITGAV HSPG2

5.41e-03132542DOID:4195 (is_marker_for)
Diseaseneuroimaging measurement

DCHS2 CTNNAL1 UBAP2 ELAC2 TOX3 TLN2 CAMTA1 BANK1 SLC4A9 AGAP3 ADAMTS3 KIF26B FAT3 CHD7 XRCC4 NR2F2 COL18A1 MACF1

5.45e-03106925418EFO_0004346
Diseaseliver cirrhosis (is_marker_for)

HNF4A IL18BP THPO BECN1

5.55e-03822544DOID:5082 (is_marker_for)
Diseasesevere acute respiratory syndrome, COVID-19

MYO7A LYST LIN7A TMEM132C TOX3 CAMTA1 COL6A3 MXRA5 ARHGEF18 PCDHA6

5.66e-0344725410EFO_0000694, MONDO_0100096
DiseaseFanconi anemia

FANCD2 FANCI

6.27e-03142542cv:C0015625
Diseasethalamus volume change measurement

FAT1 KIF26B

6.27e-03142542EFO_0021496
Diseaseesterified cholesterol measurement, low density lipoprotein cholesterol measurement

ADAMTS3 APOB

6.27e-03142542EFO_0004611, EFO_0008589
Disease5-methyluridine (ribothymidine) measurement

PCLO TYMP

6.27e-03142542EFO_0020013
DiseaseMalignant Head and Neck Neoplasm

FANCD2 FAT1 FANCI

6.44e-03442543C0278996
Diseaseornithine measurement

MED23 DPP6 OGDH

6.44e-03442543EFO_0009776
Diseasetriglycerides to total lipids in chylomicrons and extremely large VLDL percentage

PLTP APOB

7.20e-03152542EFO_0022328
DiseaseHypertriglyceridemia

PLTP APOB

7.20e-03152542C0020557
Diseasesickle cell anemia (is_implicated_in)

C3 APOB

8.18e-03162542DOID:10923 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
EEELPTATLTLTLRT

SYT13

231

Q7L8C5
SEAVTVLPASQLESR

ZNF280B

96

Q86YH2
ELSEASRNTIPLAVV

BANK1

186

Q8NDB2
TPSISQRELRIETIA

AGAP3

306

Q96P47
QRELRIETIAASSTP

AGAP3

311

Q96P47
IASDISLPIATQELR

ESYT2

756

A0FGR8
VDASVLVRQISLSPS

EP400

171

Q96L91
LELVEQVTRVESLSP

SLC4A9

151

Q96Q91
TQILVELRSSTFPES

CCDC186

116

Q7Z3E2
PTVLESELVQRIQTL

ARHGEF18

981

Q6ZSZ5
TLSVNSISTLEPVSR

CFAP410

46

O43822
LPTNVSEELVLSTTL

CAMTA1

456

Q9Y6Y1
LIQPVDTISISSLRQ

CAGE1

106

Q8TC20
PEDLIQTSSTEQLRT

BIRC6

2011

Q9NR09
QSSVQLLETIDEPLT

BIRC6

2451

Q9NR09
LSDVLDRVSDTPSIT

BIRC6

3866

Q9NR09
LVDIPRENITQSTDI

CATSPERB

111

Q9H7T0
LTVNTLDRFLTTTPV

CCNO

156

P22674
IIPQTISELQLSVSA

C4B

436

P0C0L5
PEILSRSQTQTLESL

ALS2

1336

Q96Q42
DAEATRTALTPEITL

ADGRG4

576

Q8IZF6
RTALTPEITLASTVA

ADGRG4

581

Q8IZF6
SVTLTPRTVDLTVIL

CDCP1

656

Q9H5V8
QSSLVPALTDFVRSV

CUTA

126

O60888
SLRPSDTLREVTVTV

GZMK

161

P49863
QITVTAELDRETLPI

FAT4

3461

Q6V0I7
GQRSTVLDVILTPET

ADGRV1

5571

Q8WXG9
ETVTFNSSLLRPRVI

C8orf34

256

Q49A92
VPDTESETRILLQGT

C3

971

P01024
ISPTQRAEVIRILST

ACACA

2326

Q13085
AIPTRTVAISDAAQL

EIF4EBP2

16

Q13542
IITSDSLAPRVDAIS

ACSM5

166

Q6NUN0
VPNVLLTSSDSSVII

ATF2

171

P15336
SVASVTVPIRLDTLS

C19orf84

51

I3L1E1
TISERVETQPLLRLT

ADCY7

656

P51828
TDVIPSEAINELTVL

SERPINC1

231

P01008
PSLLRNVLTEESVVR

C5AR1

316

P21730
SQVPVQTRSSILLAE

CAMSAP3

816

Q9P1Y5
SIIEPITEERASRTL

CHD7

2041

Q9P2D1
IQASDVIDTESVLPL

DMTF1

706

Q9Y222
LASVEQITIVSRPLS

ARIH2OS

196

Q8N7S6
SINSNITRVVLEPDS

RBM27

546

Q9P2N5
EPALTATATVLVSLV

PCDHA9

656

Q9Y5H5
NIDALEASIVISVSP

HSPG2

2701

P98160
RLPSLRTVSSSVIEQ

NR2F2

366

P24468
EVIITSLFSPVLENS

PCDHGA8

346

Q9Y5G5
PEITITSSINSILEN

PCDHGA11

346

Q9Y5H2
IISEIISSLPSIVND

PUM3

421

Q15397
LPRVVQTLLRTVEAS

NIBAN3

376

Q86XR2
EPALTATATVLVSLV

PCDHA2

656

Q9Y5H9
EPALTATATVLVSLV

PCDHA6

656

Q9UN73
VPNTESLESLTQIEL

PARD6B

311

Q9BYG5
LSSRTLPEIVASLTE

KIAA1549

261

Q9HCM3
TTVLSQSLEETISPR

KIAA1549

326

Q9HCM3
VSELPLRSLEETVSA

MRNIP

66

Q6NTE8
EIDILPTQLVNTSSV

PDK4

71

Q16654
SESSFTPLVVIELAQ

ANO10

11

Q9NW15
LSRLTAPVVTTQLDT

ANKRD13B

231

Q86YJ7
VTERVLAPASTLQSS

DSG2

1046

Q14126
AQPEAISTIAQSLRT

DAAM2

196

Q86T65
AALLAATVPEQRTVT

DEPDC5

1341

O75140
VITAVTLSPSELDRD

FAT1

256

Q14517
LEQVLNRVVTRASSP

FANCI

441

Q9NVI1
STPAFLETRRIQTEL

MUC16

7811

Q8WXI7
IQIEPTSSLTSGLRE

MUC16

8406

Q8WXI7
DISTEVITRLSTSPI

MUC16

9056

Q8WXI7
SPDIITEVITRLSSS

MUC16

9931

Q8WXI7
PALTATATVLVSLVE

PCDHA11

656

Q9Y5I1
IRSVDANVLTPIRSL

PODN

321

Q7Z5L7
QSIEAPLTATDTAIL

DNAJC11

166

Q9NVH1
SDPRVAQVTTLILSV

OR11A1

191

Q9GZK7
PLSTETIISLNVADT

PCDHGA6

431

Q9Y5G7
EPALTATATVLVSLV

PCDHA8

656

Q9Y5H6
EQTSIRSPQTRILLV

KLHL34

271

Q8N239
AATRPSSVLIEQLAV

MDN1

651

Q9NU22
EALPDILTSIIRTSN

LONP2

181

Q86WA8
TLTVVQPLTLDRDVA

LIN7A

16

O14910
VQRLSLSPEVLDLTS

LAMA3

2901

Q16787
PRADLQQIIVSLTES

KAT2B

121

Q92831
ALVTVSRNPLEETSA

MUC20

521

Q8N307
LQVTSLAQIILEPRS

MTMR9

341

Q96QG7
SSVPTLRSELNVVLQ

DST

1141

Q03001
LLVRATPVSQTTTAA

IL18BP

26

O95998
SIIATISPASLNLEE

KIF11

331

P52732
SRPVSIISSISEDLE

KIF26B

1226

Q2KJY2
RVTIQELTAPLLTTA

BECN1

36

Q14457
VLPITTREANNSLIS

CARF

46

Q8N187
ILVSATIPTSIEQLA

DDX59

381

Q5T1V6
LQAEVLSRQITSPVS

HNF4A

156

P41235
ILQLTRAVQETSLTP

HMGCS2

11

P54868
TFIPEQIQTLSRTLS

GRID2

931

O43424
VSLQQSPLVLSSVVE

PCLO

4631

Q9Y6V0
TRSTLVAIRPLDVST

PCSK4

516

Q6UW60
TVLSALSREPTVDIS

PDCD6IP

166

Q8WUM4
LNSLLDTVPVRSSVD

PLTP

196

P55058
LAEVRVSASTLPTVL

OR51J1

71

Q9H342
NIVVSRLDPVSLQTL

OLFM1

376

Q99784
TVPTESLARAETLVL

COL18A1

131

P39060
ISLEELRTQILSPNT

GALK2

306

Q01415
VATQTRDIDPIITRL

INTS2

1136

Q9H0H0
VVNLVVESTPTLANL

KCNS2

276

Q9ULS6
DRIVSVISSPSLTSE

MED23

1166

Q9ULK4
EVVSQTPLLRSRALV

PHRF1

1386

Q9P1Y6
VTPAELSELRSTIIN

PI4KA

856

P42356
TEFPQERSSISLVSL

KLHL41

526

O60662
TALAEIITETEVPAL

KMT2E

706

Q8IZD2
GLSTESILIPRQSET

LCN1

156

P31025
TLPSVLSQIEQDFIT

LY75

986

O60449
VATRVLELSIPASAE

LAMB2

1536

P55268
LRSPENVIETISSLL

GCN1

271

Q92616
DRVLPQLISTITASV

GCN1

736

Q92616
AVNLSVSTLPSLREE

KCNG1

241

Q9UIX4
SLVLPAEVIIAQSSI

PRDM12

81

Q9H4Q4
VLIVVTITASPSLRS

OR4C13

41

Q8NGP0
ADLVTSVLSSPIRRE

PPP4R3B

146

Q5MIZ7
ELPITQLTSSIVRRV

FOXRED2

426

Q8IWF2
LLETRLNVSDTVTLP

MFSD6

201

Q6ZSS7
TAQLSPTEISAVRQL

NOL4L

396

Q96MY1
SILIDESEPTTNIQI

NSFL1C

286

Q9UNZ2
TDILTAPRSEAVTVL

RALGAPA2

1091

Q2PPJ7
LETTAVLPVQIQLTT

LRRC70

476

Q7Z2Q7
RLTRIPAEVSQATEL

LRRC1

346

Q9BTT6
SSVPTLRSELNLLVE

MACF1

1126

Q9UPN3
VTLDPVQLESSLLRS

MACF1

4936

Q9UPN3
TVSRLDRESIPTVIL

DCHS2

1571

Q6V1P9
EDAPLSTVIALITVS

PCDHA1

361

Q9Y5I3
EPALTATATVLVSLV

PCDHA1

656

Q9Y5I3
EDTQPSAIIALISVS

PCDHA13

361

Q9Y5I0
PTLARTSTDLQVLAA

PLD4

181

Q96BZ4
EPALTATATVLVSLV

PCDHA4

656

Q9UN74
VTDRNITLSLVANPS

OGDH

361

Q02218
DTRSESLEIPISVVL

CBY2

36

Q8NA61
DPRTAVQLRSLSTVL

PIKFYVE

121

Q9Y2I7
SNTPLSTRLVSVQED

PIKFYVE

281

Q9Y2I7
EAVTSLLPQLIEVSS

APOB

361

P04114
IVLIIPQENDTRSSL

ADAMTS3

806

O15072
TSTLINTILEVQPRS

DNAH6

3831

Q9C0G6
RTAVALTTPDITLVL

HDAC10

411

Q969S8
TRESPSIQLASLEVV

HEATR5A

1616

Q86XA9
TTRRLVVLATPQVSD

GYG1

31

P46976
RIISIEIETPTQISL

DCLRE1C

81

Q96SD1
LQQSEAVILSETISP

DOCK1

1721

Q14185
SVEQTLLPLVSQITT

CTNNAL1

36

Q9UBT7
ETSLIIPSLERLVNA

CEP290

671

O15078
TERRQPLSSVSSLEV

DBNDD1

56

Q9H9R9
SQIVSVLDALIRSPE

EPHA8

886

P29322
LPIEDITNSTLVTTN

ITGAV

966

P06756
TELQTITNDPRLVFT

COL6A3

1581

P12111
SIVRSLDNSPLVIRA

FAT3

1786

Q8TDW7
REPLTAQQLETTTER

CC2D1A

791

Q6P1N0
PSLVRETSRITVLEA

ATAD3C

106

Q5T2N8
LLASISRIAQDPSSV

ATG9B

796

Q674R7
TIALTASEVINPLIE

EID2

211

Q8N6I1
SDIIDILRTPENVTQ

LYST

2661

Q99698
TVSTVEEERTLNPRL

ETHE1

201

O95571
TALQAALTVRPEIVS

MANEAL

386

Q5VSG8
RPVALTVTFALDNTT

ITGA10

751

O75578
VSSQLRVLTLSEDSP

DYNC1H1

131

Q14204
TIVRTIPVATTLSSL

KANSL3

801

Q9P2N6
VRSQPLTNDDLVTSV

KHDC1L

106

Q5JSQ8
QDITRLSSPTRLAVI

KLB

851

Q86Z14
SRPQVLVASTTVLEL

HEPACAM

146

Q14CZ8
LREIVSQTGPISLTV

DVL1

321

O14640
SDTLIRRVLEVSQAP

DPEP3

271

Q9H4B8
VTSVILLTPAEDNSL

DPP6

111

P42658
LREIVSQTGPISLTV

DVL1P1

321

P54792
LTNRSLIVTTVLEEP

GRIK3

431

Q13003
LDREANLTSSVTILP

AZU1

121

P20160
RVVTLLEPLNVRSES

C4orf54

746

D6RIA3
SLIVSPRRISVQLDS

FMN2

786

Q9NZ56
LRAVVAVPELQLSTS

DLEC1

1626

Q9Y238
AILPISVAASITAQR

DNAJC22

151

Q8N4W6
PSSRIAITLENTLVI

SDK2

156

Q58EX2
PVATLSTVERRAINL

SDK2

596

Q58EX2
ALQRLVELTTSRVTP

SBK3

21

P0C264
LSVTTVLTLVSIPER

SLC45A1

311

Q9Y2W3
QPRTATGTLSIEILE

CDH15

461

P55291
TTQEAERILLRTQTP

PPHLN1

416

Q8NEY8
SLQLLSPEERVSVTD

MOCS3

326

O95396
LELTPTTSLSTRVNR

TACR2

336

P21452
IIPQTISELQLSVSA

C4A

436

P0C0L4
RAVSVPLTLAETVAS

FTCD

446

O95954
IENTSLTVPILDVLS

FANCD2

236

Q9BXW9
AVSTTPERQTLVSLA

NR2E1

146

Q9Y466
AESTQPIRLSSIILA

NUP210L

96

Q5VU65
LNETATTITVLLRPA

PTPRK

606

Q15262
PREINIDSSTRETII

RGS13

96

O14921
VSPLATRSLEIVLST

OTOG

1721

Q6ZRI0
ALQDVPLSSVVRSII

MRPL11

131

Q9Y3B7
VISTLQILPTVREDS

DSCAM

846

O60469
IIASPLVSTDSVLVA

GPRASP1

116

Q5JY77
PVSSLTISRLIDNIS

MRPS27

66

Q92552
RDPDISVSLLTLVVT

SYT9

46

Q86SS6
LQVELTSPVFLTDIT

RGSL1

561

A5PLK6
IALVELSVPVTLSSR

TPSG1

126

Q9NRR2
LDSQSIIRPLTVEEV

SLC9C1

851

Q4G0N8
TDRPLLSTLEESVVR

SMG5

751

Q9UPR3
APESRVVAQVLTLLD

SPATA5L1

316

Q9BVQ7
LSRQLEVVESSIPSV

SYNE1

6701

Q8NF91
TVQVLSPLSDSILAE

TMEM132B

631

Q14DG7
TIQVLSPLSDSILAE

TMEM132C

641

Q8N3T6
VNLSELESIVTERPQ

SYNE2

4361

Q8WXH0
ILISTLPSVSLVEET

SYNE2

4856

Q8WXH0
TDNIILTVPTANLRT

TCAF1

666

Q9Y4C2
NTEIDVTSLRTPELT

AHCYL1

401

O43865
TELQIAVVSPLVLSE

RESF1

756

Q9HCM1
LLSVVVDTLSTNVIP

GPAM

331

Q9HCL2
LISQTRLDTSDLEPT

PDIK1L

171

Q8N165
QLRAIIEADPLTTTR

SETMAR

416

Q53H47
PERVASLDTVVSVLR

IQANK1

261

A8MXQ7
NITSLVRLSTTVPNT

PIAS1

251

O75925
STLQTVRIERSPLLD

NOPCHAP1

56

Q8N5I9
PELVIQLATSAITEA

NUP160

976

Q12769
LALEVIVTLSETATP

RANBP6

286

O60518
DAAIISTLVSSVLPV

NCKIPSD

471

Q9NZQ3
STLVSSVLPVELARD

NCKIPSD

476

Q9NZQ3
ATRVLSNTEDLPLVT

SLURP2

51

P0DP57
VVAIEALTQLSEAPS

TET1

891

Q8NFU7
TLPVELLADTRVTQS

BPIFB2

111

Q8N4F0
ILDLLSTVPTQVNSE

ADGRF5

776

Q8IZF2
SRQIDDILSVASVRP

AKR1A1

166

P14550
DILSVASVRPAVLQV

AKR1A1

171

P14550
LVVVSVSPQSRASLA

CIAO3

111

Q9H6Q4
QRTSAPEISSILSEQ

C12orf71

181

A8MTZ7
VPEASARLTQTLAIE

SEPTIN1

61

Q8WYJ6
PQIIITRASNETLVS

SPATA33

86

Q96N06
TPRSVLLELDNIIAS

PLEKHS1

211

Q5SXH7
TTSSDRTINLLEVLP

TMEM31

61

Q5JXX7
VLTLQLPVTASVREV

RAPGEF3

571

O95398
VLSETTLAQPQSLER

UBXN6

241

Q9BZV1
LQLPSTTIENISVSV

UBAP2

481

Q5T6F2
TLENIIATVDTRLPE

TNFAIP2

491

Q03169
LDLVDRQSITLISSP

ZSWIM7

46

Q19AV6
IRNVSATLVNISPDT

ELAC2

496

Q9BQ52
SVTLVDVSALRPNTT

CD96

416

P40200
LIVAETTTVPSLENL

RLF

1846

Q13129
TTTVPSLENLRVVLD

RLF

1851

Q13129
NTTIPLLLEIARQTD

TRPV1

171

Q8NER1
FLERISQLDTRSPVT

PYROXD2

361

Q8N2H3
PESAVILLSTTVLEN

RMC1

161

Q96DM3
AVLRENLSPTTIETA

STAT4

726

Q14765
TITQIERRFDIPSSL

SLCO1C1

66

Q9NYB5
ILTVTELSVPQNVSL

STAP1

116

Q9ULZ2
ITLDPQTASRSLVLS

TRIM15

296

Q9C019
SIISSLDVTDIAPSR

XRCC4

256

Q13426
AEILVTLSQVIISPA

UNQ5815/PRO19632

46

Q6UWF5
SISQIIENPRVLDSS

MTERF1

341

Q99551
SPTSLQLRSQIEESL

SASH1

101

O94885
VTALVPSEAAVRQLS

STAB1

1021

Q9NY15
VSSVAAQRLVLDTLP

RGS14

431

O43566
LTVLTPREILSSDAV

SLC7A13

261

Q8TCU3
LETVTLLPVARTDAA

SIGLEC1

756

Q9BZZ2
LDLPSITISRNLVEQ

TOX3

111

O15405
SPENRATQSILILVS

VN1R4

226

Q7Z5H5
ESRPRLSQLSVTDVT

TNXA

141

Q16473
PRQLLLQVESTTVAT

RIOX2

291

Q8IUF8
PEITVRSVLLSRSQQ

RWDD2B

116

P57060
VEAVESTLQTPLDIR

TRIM14

216

Q14142
LNSTTIEISELPVRT

TOP2A

916

P11388
EQEAILTAESIISPS

ZNF507

16

Q8TCN5
NVIVERLPSAEETLS

ZNF507

396

Q8TCN5
PQTTQELLTTLRDAS

TTC38

346

Q5R3I4
RIATAPLIEAVENLT

TLN2

1561

Q9Y4G6
TIAIIETSQPLALED

ZNF526

631

Q8TF50
TVSSRPSVEQLSSLI

TRAPPC8

1296

Q9Y2L5
ATVDSQVAIATELPL

WDCP

211

Q9H6R7
STEEVNTPLILISSA

PIGG

281

Q5H8A4
VNTAFTALRTLIPTE

SCX

91

Q7RTU7
LTSLISANAVERIVP

SLC26A7

106

Q8TE54
RSSPESRVTQSILVL

VN1R3

226

Q9BXE9
VVATQLPESTSLRLA

NAE1

126

Q13564
VDLLSALRTVINEPS

UGT2A1

421

P0DTE4
VSQLPRLESLDISNT

ZYG11A

201

Q6WRX3
EATLRTQSLSLAVIP

ZFYVE26

2136

Q68DK2
SLSTLSAIATPRIIE

THEGL

331

P0DJG4
PSVTIEQRRLAVDLS

TRRAP

1996

Q9Y4A5
ARDVTATVDSLPLIT

TYMP

201

P19971
ITDSPISAQDLLSRI

ZNF282

316

Q9UDV7
LTVQVLPSVDIDSIS

KIAA0586

796

Q9BVV6
VLSLSTAPLVQVSVE

UNC79

1676

Q9P2D8
AVPSRTSLVLTLNEL

THPO

181

P40225
ETTVAILLSETRPQN

MXRA5

1466

Q9NR99
TVSTPLSREQALDVR

MYO7A

381

Q13402
SRLTSEDRTVPLVVE

MYO9A

2066

B2RTY4
VREIETQTELLSPGS

NECTIN4

451

Q96NY8