Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesscell junction organization

DAB2IP OPRPN ERBB2 KIF1A FKRP PCDHB6 PCDHB4 LAMB2 TNR CDH5 ARHGAP33 ABHD17C NEDD4

4.27e-069746113GO:0034330
GeneOntologyBiologicalProcesssynapse organization

DAB2IP OPRPN ERBB2 KIF1A PCDHB6 PCDHB4 LAMB2 TNR ARHGAP33 ABHD17C NEDD4

4.61e-066856111GO:0050808
GeneOntologyBiologicalProcessblood vessel development

DAB2IP OPRPN AMHR2 ERBB2 LOXL1 JMJD8 CEACAM4 ANKRD17 RRAS CDH5 PRRX2 NEDD4

1.47e-059296112GO:0001568
GeneOntologyBiologicalProcessvasculature development

DAB2IP OPRPN AMHR2 ERBB2 LOXL1 JMJD8 CEACAM4 ANKRD17 RRAS CDH5 PRRX2 NEDD4

2.23e-059696112GO:0001944
GeneOntologyBiologicalProcessgliogenesis

DAB2IP OPRPN ERBB2 FKRP NTF3 LAMB2 DAAM2 RRAS

4.06e-05435618GO:0042063
GeneOntologyBiologicalProcessaxon extension involved in regeneration

LAMB2 TNR

8.55e-055612GO:0048677
GeneOntologyBiologicalProcesssprouting of injured axon

LAMB2 TNR

1.28e-046612GO:0048682
GeneOntologyBiologicalProcessretrograde neuronal dense core vesicle transport

KIF1A KIF1B

1.28e-046612GO:1990049
GeneOntologyBiologicalProcessregulation of angiogenesis

DAB2IP OPRPN ERBB2 JMJD8 CEACAM4 RRAS CDH5

2.34e-04420617GO:0045765
GeneOntologyBiologicalProcessanterograde neuronal dense core vesicle transport

KIF1A KIF1B

2.38e-048612GO:1990048
GeneOntologyBiologicalProcessblood vessel maturation

ANKRD17 CDH5

2.38e-048612GO:0001955
GeneOntologyBiologicalProcesscirculatory system development

DAB2IP OPRPN AMHR2 ERBB2 FKRP LOXL1 JMJD8 CEACAM4 ANKRD17 RRAS CDH5 PRRX2 NEDD4

2.51e-0414426113GO:0072359
GeneOntologyBiologicalProcessregulation of vasculature development

DAB2IP OPRPN ERBB2 JMJD8 CEACAM4 RRAS CDH5

2.69e-04430617GO:1901342
GeneOntologyBiologicalProcessregulation of anatomical structure morphogenesis

DAB2IP OPRPN ERBB2 KIF1A JMJD8 CEACAM4 RRAS TNR CDH5 ARHGAP33 NEDD4

3.13e-0410906111GO:0022603
GeneOntologyBiologicalProcessglial cell differentiation

OPRPN ERBB2 FKRP NTF3 LAMB2 DAAM2

3.67e-04321616GO:0010001
GeneOntologyBiologicalProcessMDA-5 signaling pathway

ANKRD17 OAS3

4.65e-0411612GO:0039530
GeneOntologyBiologicalProcesspositive regulation of angiogenesis

OPRPN JMJD8 CEACAM4 RRAS CDH5

4.83e-04220615GO:0045766
GeneOntologyBiologicalProcesspositive regulation of vasculature development

OPRPN JMJD8 CEACAM4 RRAS CDH5

5.14e-04223615GO:1904018
GeneOntologyBiologicalProcesscalcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

PCDHB6 PCDHB4 CDH5

5.19e-0453613GO:0016339
GeneOntologyBiologicalProcessdense core granule cytoskeletal transport

KIF1A KIF1B

5.57e-0412612GO:0099519
MousePhenoabnormal synaptic vesicle number

KIF1A KIF1B TNR NEDD4

2.00e-0542544MP:0004792
MousePhenoabnormal synaptic vesicle morphology

KIF1A KIF1B TNR NEDD4

4.34e-0551544MP:0004769
DomainKinesin-like_KIF1-typ

KIF1A KIF1B

7.12e-054652IPR022140
DomainKIF1B

KIF1A KIF1B

7.12e-054652PF12423
DomainKinesin_assoc

KIF1A KIF1B

1.77e-046652PF16183
DomainKinesin_assoc

KIF1A KIF1B

1.77e-046652IPR032405
DomainDUF3694

KIF1A KIF1B

1.77e-046652PF12473
DomainKinesin-like

KIF1A KIF1B

1.77e-046652IPR022164
DomainNPIP

NPIPA5 NPIPA7

1.06e-0314652IPR009443
DomainFHA

KIF1A KIF1B

4.25e-0328652SM00240
Pubmed

Solution structure of a Nedd4 WW domain-ENaC peptide complex.

SCNN1B NEDD4

3.55e-06266211323714
Pubmed

The neuron-specific kinesin superfamily protein KIF1A is a unique monomeric motor for anterograde axonal transport of synaptic vesicle precursors.

KIF1A KIF1B

3.55e-0626627539720
Pubmed

BORC Functions Upstream of Kinesins 1 and 3 to Coordinate Regional Movement of Lysosomes along Different Microtubule Tracks.

KIF1A KIF1B

1.06e-05366227851960
Pubmed

Girdin/GIV regulates transendothelial permeability by controlling VE-cadherin trafficking through the small GTPase, R-Ras.

RRAS CDH5

1.06e-05366225869066
Pubmed

A disorganized innervation of the inner ear persists in the absence of ErbB2.

ERBB2 NTF3

1.06e-05366216630588
Pubmed

In vivo optical trapping indicates kinesin's stall force is reduced by dynein during intracellular transport.

KIF1A KIF1B

1.06e-05366223404705
Pubmed

The Daam2-VHL-Nedd4 axis governs developmental and regenerative oligodendrocyte differentiation.

DAAM2 NEDD4

2.12e-05466232792353
Pubmed

Multiple WW domains, but not the C2 domain, are required for inhibition of the epithelial Na+ channel by human Nedd4.

SCNN1B NEDD4

2.12e-05466211359767
Pubmed

Nedd4-1 binds and ubiquitylates activated FGFR1 to control its endocytosis and function.

SCNN1B NEDD4

2.12e-05466221765395
Pubmed

The Molecular Motor KIF1A Transports the TrkA Neurotrophin Receptor and Is Essential for Sensory Neuron Survival and Function.

KIF1A KIF1B

2.12e-05466227263974
Pubmed

GRK2 interacts with and phosphorylates Nedd4 and Nedd4-2.

SCNN1B NEDD4

2.12e-05466217544362
Pubmed

Human Nedd4 interacts with the human epithelial Na+ channel: WW3 but not WW1 binds to Na+-channel subunits.

SCNN1B NEDD4

2.12e-05466210642508
Pubmed

All three WW domains of murine Nedd4 are involved in the regulation of epithelial sodium channels by intracellular Na+.

SCNN1B NEDD4

2.12e-05466210212229
Pubmed

Ubiquitin-protein ligase WWP2 binds to and downregulates the epithelial Na(+) channel.

SCNN1B NEDD4

3.53e-05566212167593
Pubmed

KIF1Bbeta- and KIF1A-mediated axonal transport of presynaptic regulator Rab3 occurs in a GTP-dependent manner through DENN/MADD.

KIF1A KIF1B

3.53e-05566218849981
Pubmed

Differential effects of extracellular ATP on chloride transport in cortical collecting duct cells.

CLCA2 SCNN1B

3.53e-05566222647633
Pubmed

Functionally reduced sensorimotor connections form with normal specificity despite abnormal muscle spindle development: the role of spindle-derived neurotrophin 3.

ERBB2 NTF3

3.53e-05566219369542
Pubmed

COMMD1 downregulates the epithelial sodium channel through Nedd4-2.

SCNN1B NEDD4

3.53e-05566220237237
Pubmed

Interaction of WW domains with hematopoietic transcription factor p45/NF-E2 and RNA polymerase II.

WBP1 NEDD4

3.53e-0556629305852
Pubmed

The Nedd4-like protein KIAA0439 is a potential regulator of the epithelial sodium channel.

SCNN1B NEDD4

9.86e-05866211244092
Pubmed

Osterix functions downstream of anti-Müllerian hormone signaling to regulate Müllerian duct regression.

AMHR2 SP7

9.86e-05866230061417
Pubmed

HIV-1 capsids bind and exploit the kinesin-1 adaptor FEZ1 for inward movement to the nucleus.

KIF1A KIF1B

9.86e-05866225818806
Pubmed

ERBB3-dependent AKT and ERK pathways are essential for atrioventricular cushion development in mouse embryos.

ERBB2 CDH5

1.27e-04966234714866
Pubmed

Functional regulation of the epithelial Na+ channel by IkappaB kinase-beta occurs via phosphorylation of the ubiquitin ligase Nedd4-2.

SCNN1B NEDD4

1.27e-04966218981174
Pubmed

Notch signaling regulates Hey2 expression in a spatiotemporal dependent manner during cardiac morphogenesis and trabecular specification.

ERBB2 CDH5

1.27e-04966229422515
Pubmed

Identification of multiple proteins expressed in murine embryos as binding partners for the WW domains of the ubiquitin-protein ligase Nedd4.

WBP1 NEDD4

1.27e-04966211042109
Pubmed

Amhr2-Cre-Mediated Global Tspo Knockout.

AMHR2 TP53INP2

1.58e-041066232099945
Pubmed

Respiratory distress and perinatal lethality in Nedd4-2-deficient mice.

SCNN1B NEDD4

1.93e-041166221505443
Pubmed

Cell autonomous roles of Nedd4 in craniofacial bone formation.

SP7 NEDD4

2.31e-041266226681395
Pubmed

Coordinated transport of phosphorylated amyloid-beta precursor protein and c-Jun NH2-terminal kinase-interacting protein-1.

KIF1A KIF1B

2.31e-041266216301330
Pubmed

Protocadherins.

PCDHB6 PCDHB4

2.73e-041366212231349
Pubmed

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

SCNN1B NEDD4

2.73e-041366215123669
Pubmed

Disorganized innervation and neuronal loss in the inner ear of Slitrk6-deficient mice.

ERBB2 NTF3

3.18e-041466219936227
Pubmed

Comparative interactome analysis of α-arrestin families in human and Drosophila.

EPB41L4B SAP18 LAMB2 ZCCHC2 NEDD4

3.26e-0431366538270169
Pubmed

Intrafusal-fiber LRP4 for muscle spindle formation and maintenance in adult and aged animals.

ERBB2 NTF3

3.67e-041566236765071
Pubmed

Sequence identification of 2,375 human brain genes.

KIF1A DAAM2

3.67e-04156621538749
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

PODNL1 ELOA YIF1A SAP18 LOXL1 MRPS34 LAMB2 OAS3 FUT8 NEDD4

3.89e-041451661030550785
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

YIF1A RARS1 KIF1A SLC12A9 FKRP ARFGEF1 ANKRD17 FUT8

4.03e-0494266831073040
Pubmed

Postsynaptic and differential localization to neuronal subtypes of protocadherin beta16 in the mammalian central nervous system.

PCDHB6 PCDHB4

4.74e-041766218279309
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

RARS1 KIF1A ZNF592 MRPS34 LAMB2 ANKRD17 RRAS FUT8 PRRC2A INO80E

4.96e-041497661031527615
Pubmed

Identification of novel human WW domain-containing proteins by cloning of ligand targets.

WBP1 SCNN1B

5.32e-04186629169421
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

ELOA ZNF592 KIF1B ANKRD17 PHF10 PRRC2A ANKS1A

6.56e-0477466715302935
Pubmed

The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number.

PCDHB6 PCDHB4

6.59e-042066211322959
Pubmed

Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.

NTF3 LAMB2 SP7 NEDD4

6.95e-0421066416537572
Pubmed

NRG1 signalling regulates the establishment of Sertoli cell stock in the mouse testis.

ERBB2 CDH5

7.28e-042166230040984
Pubmed

Erg is a crucial regulator of endocardial-mesenchymal transformation during cardiac valve morphogenesis.

ERBB2 CDH5

7.28e-042166222932696
Pubmed

Blood flow controls bone vascular function and osteogenesis.

CDH5 SP7

7.99e-042266227922003
Pubmed

Loss of Gata5 in mice leads to bicuspid aortic valve.

ERBB2 CDH5

9.53e-042466221633169
Pubmed

Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome.

KIF1A KIF1B

1.03e-03256629275178
Pubmed

Genome-wide association analyses identify variants in developmental genes associated with hypospadias.

DAAM2 DENND2B

1.03e-032566225108383
Pubmed

Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry.

DAB2IP DDX17 RARS1 ARFGEF1 ANKRD17

1.11e-0341166536652389
Pubmed

Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.

DDX17 SAP18 PHF10 PRRC2A

1.21e-0324466429884807
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ERBB2 ZNF592 PANK4 ANKRD17 OAS3 PHF10 ARHGAP33 INO80E

1.21e-03111666831753913
Pubmed

The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.

ANKRD17 PHF10 ABHD17C NEDD4

1.23e-0324566419521500
Pubmed

YAP and TAZ are required for the postnatal development and the maintenance of the structural integrity of the oviduct.

AMHR2 DDX17

1.39e-032966232520726
Pubmed

Embryonic forebrain transcriptome of mice with polyalanine expansion mutations in the ARX homeobox gene.

SACS TNR

1.59e-033166227798109
Pubmed

Regulation of ETAA1-mediated ATR activation couples DNA replication fidelity and genome stability.

OAS3 MCM10 PRRC2A

1.64e-0312266331615875
Pubmed

A germline-specific class of small RNAs binds mammalian Piwi proteins.

FKRP JMJD8 LAMB2 PRRC2A ANKS1A

1.66e-0345066516751776
Pubmed

TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.

ELOA DDX17 SAP18 MTERF3 MCM10 PRRC2A ABHD17C

1.80e-0392266727609421
CoexpressionHAY_BONE_MARROW_STROMAL

PODNL1 KCNT2 CLCA2 EPB41L4B LOXL1 PCDHB6 LAMB2 DAAM2 CDH5 DENND2B PRRX2

3.11e-067676611M39209
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OPRPN KCNT2 SACS LOXL1 SSUH2

2.74e-06148665dfd3f2c4b884ea9e23831a242a89ac985b409640
ToppCellAT1_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

DAB2IP ERBB2 KCNT2 SCNN1B LAMB2

6.92e-061796651603117b52623663458a977c94bf7f9f6c1114b8
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PODNL1 C14orf93 PANK4 ARHGAP33

5.57e-051406647b359bfbd404ab06d799048252f4985d85852048
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF311 KCNT2 DAAM2 MCM10

8.07e-05154664b6e982e341c6cfb6ff80a318078fcb10c36d182f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF311 KCNT2 DAAM2 MCM10

8.07e-05154664d76fd51a4587decbfe1dde1c8a9b880c5fa18e4a
ToppCellLPS-antiTNF-Endothelial-Mes-Like-Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZBTB7C FKRP MTERF3 PRRX2

1.08e-0416666494a00edf66d54bc5f7343daea700ca26cf38fd90
ToppCellwk_08-11-Mesenchymal-Fibroblast-Airway_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ZBTB7C NTF3 PSTPIP2 PRRX2

1.26e-04173664b23b408acc29a667cce104429afef1a6cf2720a5
ToppCellBasal_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

PODNL1 CLCA2 LOXL1 SCNN1B

1.29e-04174664a0060be3940043015dcc49a5157de5541aed24a1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KCNT2 NTF3 DAAM2 DENND2B

1.41e-0417866478a0c6340001a77f5b2d890b6263f574af2e72da
ToppCellfacs-Kidney-nan-24m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LOXL1 DAAM2 ADGRA1 PRRX2

1.47e-04180664f9f8245cbcdea18c15e2976c85b72c6807309787
ToppCellAT1_cells-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

DAB2IP KCNT2 SCNN1B LAMB2

1.47e-041806642d52cb5f77dde0e3dccac1333d4ec67ec680fcb2
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB2 RRAS CDH5 ANKS1A

1.47e-041806642405aa5699a8d8cf4c6b3dca07510e774728ac50
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB2 RRAS CDH5 ANKS1A

1.47e-041806649c47852c0a723e2f5cd6898afff4c31a0da06905
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB2 RRAS CDH5 ANKS1A

1.47e-04180664499d5fe71e0dc20cffdf85e3b3f14eb4e83e3a3d
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-1|TCGA-Thryoid / Sample_Type by Project: Shred V9

PODNL1 LOXL1 PSTPIP2 PRRX2

1.57e-0418366406e4b05d86a7d643569e19575c2c9aa351d33f29
ToppCellwk_20-22-Mesenchymal-Chondrocyte-intermediate_chondrocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

KCNT2 DAAM2 CBR3 ABHD17C

1.57e-041836641464b5c4425e8776c4aeb4d2b560481d4bf13931
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KCNT2 DAAM2 DENND2B PRRX2

1.57e-04183664667717366cb181b8a04a347e64f0f5a4dfc6ee7f
ToppCell10x5'v1-week_12-13-Mesenchymal_myocytic|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

PODNL1 EPB41L4B DAAM2 SP7

1.60e-04184664437bc6c983849c1c3ff85f0dee091cf7010a4665
ToppCell10x5'v1-week_12-13-Mesenchymal_myocytic-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

PODNL1 EPB41L4B DAAM2 SP7

1.60e-04184664d1d5dd1701dff4eedf1cebbb9f4cd603aa0009c1
ToppCelldroplet-Lung-nan-21m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AMHR2 ZBTB7C EPB41L4B SCNN1B

1.60e-041846647cc3b9bba1f600b40b02fe2456b5d007dbf9fa37
ToppCelldroplet-Lung-nan-21m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AMHR2 ZBTB7C EPB41L4B SCNN1B

1.60e-0418466453b71c4ac86dc5e42763b8f64fbc917177531017
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2IP CLCA2 CDH5 SSUH2

1.63e-0418566462cfcb0e2a9e6718e6b200dfbb1a81eaead229b5
ToppCell10x3'2.3-week_12-13-Mesenchymal_myocytic-stroma-muscle|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

PODNL1 ERBB2 KIF1A SP7

1.63e-041856640094f9baddb20214d2a2c166f1637d1a9cf1169a
ToppCell10x5'v1-week_12-13-Mesenchymal_myocytic-stroma-muscle|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

PODNL1 EPB41L4B DAAM2 SP7

1.67e-04186664fbc4ba4a7a8e5902a1b0add52ece0d6da85a8a5f
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZBTB7C KCNT2 NTF3 DAAM2

1.67e-041866644780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZBTB7C KCNT2 NTF3 DAAM2

1.67e-04186664a95744b8649096bd7cfc3591a02841fa411085b3
ToppCellControl-Epithelial-ATI|Epithelial / Disease state, Lineage and Cell class

KCNT2 SCNN1B LAMB2 RRAS

1.70e-041876643a032432f780525f4f4c2a358897d9989b1ecae7
ToppCell368C-Epithelial_cells-Epithelial-I_(AT1)-|368C / Donor, Lineage, Cell class and subclass (all cells)

ERBB2 DAAM2 OAS3 ABHD17C

1.74e-04188664c74771584b3ba9561a99a54bf55a9203ddf8eff8
ToppCell368C-Epithelial_cells-Epithelial-I_(AT1)|368C / Donor, Lineage, Cell class and subclass (all cells)

ERBB2 DAAM2 OAS3 ABHD17C

1.74e-041886649155b9a92496e75646778c025b02947e9e9ec73a
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCNT2 LOXL1 ADGRA1 PRRX2

1.74e-04188664bba6b273bd47dd0e27fde914e9e6fc9d76fd5176
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TNR CDH5 DENND2B NEDD4

1.77e-04189664b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZBTB7C KCNT2 NTF3 DAAM2

1.77e-04189664975e7aa3b862a8b07c2ab8426a14f5cc54998aca
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZBTB7C KCNT2 NTF3 DAAM2

1.77e-04189664127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZBTB7C KCNT2 NTF3 DAAM2

1.77e-041896642cfb4d12f75678d1619f4743838a0e954bd57761
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZBTB7C KCNT2 NTF3 DAAM2

1.81e-0419066473d94fbae92029745989a8712eed8b99fd84c193
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KCNT2 NTF3 DAAM2 DENND2B

1.85e-04191664a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCNT2 NTF3 LOXL1 PRRX2

1.85e-0419166424dc77ee8de01b42559f92721655f4281b114e17
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KCNT2 NTF3 DAAM2 DENND2B

1.85e-041916648f6d592edc32fdb901af30501d4360512334e8c2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZBTB7C KCNT2 NTF3 DAAM2

1.88e-04192664bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZBTB7C KCNT2 NTF3 DAAM2

1.88e-04192664b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCellAT1_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

DAB2IP KCNT2 SCNN1B LAMB2

1.88e-041926640444f9e9cef7403e220e862b5a787443d3f5c9ac
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KCNT2 NTF3 DAAM2 DENND2B

1.92e-04193664f1199518c3626fd29bfce65070dd21a660671213
ToppCell(1)_Osterolineage_cells|World / Cell class and subclass of bone marrow stroma cells in homeostatis

PODNL1 LOXL1 PRRX2 SP7

1.92e-04193664035eeea9f77c4bf9cd85f07fa791b6c857be76b5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KCNT2 NTF3 LOXL1 DAAM2

1.96e-04194664cf0244a29934e515446ac917d3c30672b460fb04
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KCNT2 NTF3 DAAM2 DENND2B

1.96e-04194664e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KCNT2 NTF3 LOXL1 DAAM2

1.96e-04194664ba7f971fb9a19423602da60770f23d9fead4a451
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KCNT2 NTF3 DAAM2 DENND2B

1.96e-04194664ebb038f94f49f5c655578d1b018676e10c6b7e3c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KCNT2 NTF3 DAAM2 DENND2B

2.00e-04195664edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCell(1)_Osterolineage_cells-(11)_OLC-2|World / Cell class and subclass of bone marrow stroma cells in homeostatis

NTF3 LOXL1 DAAM2 PRRX2

2.00e-0419566478978d85273e5463a7f43e4c121e647fa6aba42b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KCNT2 NTF3 DAAM2 DENND2B

2.04e-04196664b8759e6231e0254797d6c30930407b79440c57bb
ToppCell(00)_Basal-(0)_Reference|(00)_Basal / shred by cell type by condition

NPIPA5 SCNN1B WDR83OS PRRC2A

2.04e-04196664ba03530a20d7b29902721fd50df8d860557ddefa
ToppCellEnterocyte-C_05|Enterocyte / shred on cell type and cluster

ZBTB7C SCNN1B OAS3 ABHD17C

2.04e-04196664c307e5a70186567c62da938caa21749dc0e929d0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KCNT2 NTF3 DAAM2 DENND2B

2.04e-04196664fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KCNT2 NTF3 DAAM2 DENND2B

2.04e-04196664802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KCNT2 SCNN1B LAMB2 RRAS

2.04e-04196664eb68f7954e7c2f86d05e740e95b6e74805a6053f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KCNT2 NTF3 DAAM2 DENND2B

2.08e-04197664ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KCNT2 NTF3 DAAM2 DENND2B

2.08e-0419766437f6b6f2809b952382eaebb642b0aad6371f4251
ToppCell(2)_5-FU-(3)_LEPR+_perivascular_cells|World / Stress and Cell class

PODNL1 EPB41L4B RRAS DENND2B

2.08e-04197664434ae0231972acba12d06279908cf407e70511ac
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KCNT2 NTF3 DAAM2 DENND2B

2.12e-0419866479576525a10ed3e3a9d1608077cd16ecda23376f
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-Stromal_4_(MMP1+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PODNL1 LOXL1 DENND2B PRRX2

2.12e-04198664229588189825b1080181db9515185677b742c668
ToppCell10x5'v1-week_14-16-Mesenchymal_myocytic|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PODNL1 LOXL1 DAAM2 SP7

2.12e-0419866455d2ed345101bec4b73f1242ba8c4d73073b7e88
ToppCell10x5'v1-week_14-16-Mesenchymal_myocytic-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PODNL1 LOXL1 DAAM2 SP7

2.12e-041986648602a518b5913625b1dd3cbc3c7e6efde0d5d942
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RRAS FUT8 CDH5 SSUH2

2.16e-04199664a3ec743b978ba8fdf1677b4971b5731f50ddd30f
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RRAS FUT8 CDH5 SSUH2

2.16e-041996649b02acae6325b0ac9642438a4431285ff396e5fe
ToppCellNasal_Brush-Epithelial-Goblet_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

LOXL1 OAS3 CBR3 PRRX2

2.16e-04199664aa6f1390283617c7f9aaf91d379024832ea24a9e
ToppCellcontrol-unassigned|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

WBP1 ZNF592 ARHGAP33 ANKS1A

2.16e-0419966450e2da35edff1aadef939cfbd4549f73c1a07717
ToppCellcontrol-unassigned|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

WBP1 ZNF592 ARHGAP33 ANKS1A

2.16e-041996645db7c8089172ac8e796613b3cef618d87007a0ab
ToppCellNasal_Brush-Epithelial-Goblet_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

LOXL1 OAS3 CBR3 PRRX2

2.16e-041996642ac716f887687b5109fb9feced75d5c62646a268
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ZBTB7C KCNT2 NTF3 DAAM2

2.20e-042006649169a9ec8e9ab95d90a64c5a19ac666a5cf82313
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LOXL1 OAS3 CBR3 DENND2B

2.20e-042006640f6620a5baace704518d42fa2f3f90751240f7dd
ToppCellLPS_IL1RA-Endothelial-Endothelial-Artery|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

LAMB2 FUT8 CDH5 SSUH2

2.20e-04200664ac9ead34afa14067171833f5c277eaf06db7b02e
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte|LPS_only / Treatment groups by lineage, cell group, cell type

ZBTB7C KCNT2 NTF3 DAAM2

2.20e-042006648c8ef2b19ab5b1bfc0fae6c38a330f464f28e86f
ToppCellControl_saline-Endothelial-Endothelial-Activated_Alv_Cap|Control_saline / Treatment groups by lineage, cell group, cell type

OAS3 RRAS CDH5 NEDD4

2.20e-04200664be55cef682ba87250dad97689332c8820b3a7420
ToppCellLPS_only-Endothelial-Endothelial-Artery|LPS_only / Treatment groups by lineage, cell group, cell type

LAMB2 FUT8 CDH5 SSUH2

2.20e-04200664b17eb1587ca86c3d40515128a00a8d8fd787fccf
Drugphosphotyrosine (pY

WBP1 ERBB2 KIF1A KIF1B SCNN1B ANKS1A NEDD4

1.63e-06203647CID000030819
Diseasesynucleinopathy (biomarker_via_orthology)

KIF1A KIF1B

2.43e-054602DOID:0050890 (biomarker_via_orthology)
DiseaseLiddle syndrome (implicated_via_orthology)

SCNN1B NEDD4

2.43e-054602DOID:0050477 (implicated_via_orthology)
Diseasehypospadias

DAAM2 DENND2B SP7

6.93e-0539603EFO_0004209
Diseasenervous system disease (implicated_via_orthology)

KIF1A KIF1B

2.65e-0412602DOID:863 (implicated_via_orthology)
Diseaselysophosphatidylethanolamine 16:0 measurement

ANKRD17 TNR

1.28e-0326602EFO_0010366
Diseasefactor VIII measurement, coronary artery disease

DAB2IP PRRC2A ANKS1A

1.60e-03113603EFO_0001645, EFO_0004630
Diseasesmoking behavior, BMI-adjusted waist circumference

LOXL1 KIF1B ANKS1A

1.99e-03122603EFO_0004318, EFO_0007789

Protein segments in the cluster

PeptideGeneStartEntry
PSPLQRYSEDPTVPL

ERBB2

1106

P04626
PLPSPRTATPIYEEL

CEACAM4

211

O75871
PESPQLRYLPPQTVD

ARFGEF1

241

Q9Y6D6
DTDQPPYPRQPLLRF

ADGRA1

121

Q86SQ6
LTLRPPSLAAPYAPV

ANKS1A

911

Q92625
LLDYPNNLLSAPPPD

ANKRD17

716

O75179
VLSPPRSPIYPLSDS

DENND2B

36

P78524
AKPPRPALDARPSLY

CDH5

671

P33151
LRYKPPPSECNPALD

WDR83OS

16

Q9Y284
DLRPDSSPPPFQLAY

AMHR2

426

Q16671
LPIPKSSPDDPNYSL

PSTPIP2

311

Q9H939
QPVAPRPTALSPDYL

PRRX2

186

Q99811
PPNLLSTLQYPRPSS

DAB2IP

936

Q5VWQ8
LPQDPYPSSDVPLRK

DAAM2

581

Q86T65
DVPLYPLPTENPRLE

NEDD4

526

P46934
DTLYSPLPPELLPTE

KIF1B

796

O60333
ALEPPYLPVRSSDTP

LOXL1

326

Q08397
VLDPAIPIPDPYSSR

LAMB2

221

P55268
YDESPPPRPKLSALA

MCM10

641

Q7L590
LIRPDPLAYLPNSEP

KCNT2

1101

Q6UVM3
LSDSTPLEPPPLYLM

NTF3

106

P20783
FPSDYLALQLPEPSP

INO80E

141

Q8NBZ0
DLPLLLDPPSYVPDT

PANK4

421

Q9NVE7
TYSLLPPQDPHLPLA

PCDHB4

486

Q9Y5E5
QLSYLPPSLPPSLER

PODNL1

206

Q6PEZ8
TALYEPPLDPELPAL

PHF10

281

Q8WUB8
PPPYLPRQQSDGSLL

ARHGAP33

966

O14559
DLPLPAIQANYRPLP

ELOA

511

Q14241
PSAEAQLLPPELYNP

C14orf93

481

Q9H972
LPPEPTYTVLAPEQR

ABHD17C

36

Q6PCB6
PVYLALLPPDATEPQ

CBR3

251

O75828
PLLPRYSPQSLTDPQ

KIAA1210

1016

Q9ULL0
ALPSPAIRAPLPDLY

DDX17

61

Q92841
VAADTLPYPPLALPR

FKRP

81

Q9H9S5
PPPNYDSLRLQPLDV

SCNN1B

616

P51168
TRYPDLLPFPQIPND

SACS

4536

Q9NZJ4
YPLPSPVLSSSDRLP

EPB41L4B

471

Q9H329
DTLYSPLPPDLLPPE

KIF1A

756

Q12756
DPPLPPASFTLRDYV

MTERF3

136

Q96E29
PAPASLPPAYALELL

OAS3

621

Q9Y6K5
YSLLPPQDPHLPLSS

PCDHB6

486

Q9Y5E3
LYPLPPSADDNLKTP

NPIPA7

271

E9PJI5
LYPLPPSADDNLKTP

NPIPA8

271

P0DM63
PPYLPLAVPEDLADR

FUT8

301

Q9BYC5
APEDSLASVPYPPLL

MRPS34

156

P82930
AYPDLENPPLLVTPS

RARS1

91

P54136
PSERLLYPLPPSADD

NPIPA5

266

E9PKD4
LYPLPPSADDNLKTP

NPIPA5

271

E9PKD4
DPRLLQGRPPLDFYP

PRRC2A

731

P48634
PPYDSRLNSPLSLPF

OPRPN

51

Q99935
DYLDIAITPPNRAPP

SAP18

131

O00422
LDSYLAPALPLDPPP

SELENOV

141

P59797
PLAPPTELLERLPSY

SSUH2

21

Q9Y2M2
LFIPPNSDPVPARDY

CLCA2

886

Q9UQC9
LRYAPPLPPSNDTLD

ZCCHC2

1161

Q9C0B9
APLPPRQDLNAPDLY

YIF1A

126

O95070
LIIDLPDSYAAPPSP

TP53INP2

36

Q8IXH6
LASLPPPSLYLSPEL

SPEM2

226

Q0P670
LNPQLPTYPSDFAPL

SP7

191

Q8TDD2
PLYAPNLSPPADSRI

ZNF592

566

Q92610
TALTFLYLPRPPADP

SLC12A9

866

Q9BXP2
DPSPPADRLILNYSP

TNR

796

Q92752
YPKANIPDRRPSLSP

ZBTB7C

236

A1YPR0
RKYQEQELPPSPPSA

RRAS

191

P10301
TLPDLEDYSPCALPP

WBP1

236

Q96G27
LPQESALLPAPYPAF

ZNF311

26

Q5JNZ3
LRDTYPALPPSARPL

JMJD8

216

Q96S16