Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	actin binding	CTNNAL1 DST SPATA31A3 SPATA31A7 SPTBN2 RDX MACF1 PLEC DMD SPATA31A5	1.50e-05	479	77	10	GO:0003779
GeneOntologyMolecularFunction	molecular function inhibitor activity	SERPINB8 SERPINB13 NEDD4L POT1 SERPINB2 KCNK2 TFDP3 ROCK1 C3 LYAR	9.45e-05	596	77	10	GO:0140678
GeneOntologyMolecularFunction	cytoskeletal protein binding	CTNNAL1 DST SPATA31A3 SPATA31A7 SPTBN2 RDX MACF1 ROCK1 TTLL1 PLEC DMD SPATA31A5 FRMD5	2.72e-04	1099	77	13	GO:0008092
GeneOntologyMolecularFunction	cell adhesion molecule binding	CTNNAL1 DST SWAP70 SPTBN2 RDX MACF1 PLEC DMD FRMD5	4.86e-04	599	77	9	GO:0050839
GeneOntologyMolecularFunction	endopeptidase inhibitor activity	SERPINB8 SERPINB13 SERPINB2 ROCK1 C3	6.58e-04	180	77	5	GO:0004866
GeneOntologyMolecularFunction	peptidase inhibitor activity	SERPINB8 SERPINB13 SERPINB2 ROCK1 C3	7.82e-04	187	77	5	GO:0030414
GeneOntologyMolecularFunction	potassium channel inhibitor activity	NEDD4L KCNK2	7.89e-04	11	77	2	GO:0019870
GeneOntologyMolecularFunction	dystroglycan binding	PLEC DMD	9.45e-04	12	77	2	GO:0002162
GeneOntologyMolecularFunction	endopeptidase regulator activity	SERPINB8 SERPINB13 SERPINB2 ROCK1 C3	1.08e-03	201	77	5	GO:0061135
GeneOntologyCellularComponent	centriole	POC1B ROCK1 CEP152 POC5 HERC2 SPICE1	3.58e-05	172	75	6	GO:0005814
GeneOntologyCellularComponent	costamere	TRPC1 PLEC DMD	6.50e-05	22	75	3	GO:0043034
GeneOntologyCellularComponent	sarcolemma	DST LAMA2 RDX PLEC DMD	6.07e-04	190	75	5	GO:0042383
GeneOntologyCellularComponent	hemidesmosome	DST PLEC	6.84e-04	11	75	2	GO:0030056
Domain	Spectrin_repeat	DST SPTBN2 MACF1 PLEC DMD CCDC141	1.64e-09	29	76	6	IPR002017
Domain	Actinin_actin-bd_CS	DST SPTBN2 MACF1 PLEC DMD	3.10e-08	23	76	5	IPR001589
Domain	Spectrin	DST SPTBN2 MACF1 DMD CCDC141	3.10e-08	23	76	5	PF00435
Domain	ACTININ_2	DST SPTBN2 MACF1 PLEC DMD	3.10e-08	23	76	5	PS00020
Domain	ACTININ_1	DST SPTBN2 MACF1 PLEC DMD	3.10e-08	23	76	5	PS00019
Domain	Spectrin/alpha-actinin	DST SPTBN2 MACF1 PLEC DMD	1.80e-07	32	76	5	IPR018159
Domain	SPEC	DST SPTBN2 MACF1 PLEC DMD	1.80e-07	32	76	5	SM00150
Domain	-	DST MACF1 PLEC	1.28e-06	6	76	3	3.90.1290.10
Domain	Plectin_repeat	DST MACF1 PLEC	2.24e-06	7	76	3	IPR001101
Domain	Plectin	DST MACF1 PLEC	2.24e-06	7	76	3	PF00681
Domain	PLEC	DST MACF1 PLEC	2.24e-06	7	76	3	SM00250
Domain	CH	DST SPTBN2 MACF1 PLEC DMD	6.67e-06	65	76	5	SM00033
Domain	CH	DST SPTBN2 MACF1 PLEC DMD	9.61e-06	70	76	5	PF00307
Domain	-	DST SPTBN2 MACF1 PLEC DMD	1.03e-05	71	76	5	1.10.418.10
Domain	CH	DST SPTBN2 MACF1 PLEC DMD	1.18e-05	73	76	5	PS50021
Domain	CH-domain	DST SPTBN2 MACF1 PLEC DMD	1.35e-05	75	76	5	IPR001715
Domain	DUF4599	SPATA31A3 SPATA31A7 SPATA31A5	1.39e-05	12	76	3	PF15371
Domain	DUF4599	SPATA31A3 SPATA31A7 SPATA31A5	1.39e-05	12	76	3	IPR027970
Domain	HECT	NEDD4L WWP1 HERC2	1.77e-04	27	76	3	PF00632
Domain	HECTc	NEDD4L WWP1 HERC2	1.77e-04	27	76	3	SM00119
Domain	HECT_dom	NEDD4L WWP1 HERC2	1.77e-04	27	76	3	IPR000569
Domain	HECT	NEDD4L WWP1 HERC2	1.77e-04	27	76	3	PS50237
Domain	GAR	DST MACF1	2.43e-04	6	76	2	PS51460
Domain	-	DST MACF1	2.43e-04	6	76	2	3.30.920.20
Domain	GAS_dom	DST MACF1	2.43e-04	6	76	2	IPR003108
Domain	GAS2	DST MACF1	2.43e-04	6	76	2	PF02187
Domain	GAS2	DST MACF1	2.43e-04	6	76	2	SM00243
Domain	Serpin_CS	SERPINB8 SERPINB13 SERPINB2	2.95e-04	32	76	3	IPR023795
Domain	Serpin_dom	SERPINB8 SERPINB13 SERPINB2	4.20e-04	36	76	3	IPR023796
Domain	DHC_N1	DNAH9 DYNC1H1	4.50e-04	8	76	2	PF08385
Domain	Dynein_heavy_dom-1	DNAH9 DYNC1H1	4.50e-04	8	76	2	IPR013594
Domain	SERPIN	SERPINB8 SERPINB13 SERPINB2	4.55e-04	37	76	3	SM00093
Domain	SERPIN	SERPINB8 SERPINB13 SERPINB2	4.55e-04	37	76	3	PS00284
Domain	Serpin	SERPINB8 SERPINB13 SERPINB2	4.93e-04	38	76	3	PF00079
Domain	Serpin_fam	SERPINB8 SERPINB13 SERPINB2	5.33e-04	39	76	3	IPR000215
Domain	WW	NEDD4L WWP1 DMD	9.23e-04	47	76	3	PF00397
Domain	WW	NEDD4L WWP1 DMD	9.82e-04	48	76	3	SM00456
Domain	WW_DOMAIN_2	NEDD4L WWP1 DMD	1.17e-03	51	76	3	PS50020
Domain	WW_DOMAIN_1	NEDD4L WWP1 DMD	1.17e-03	51	76	3	PS01159
Domain	WW_dom	NEDD4L WWP1 DMD	1.24e-03	52	76	3	IPR001202
Domain	Dynein_heavy_chain_D4_dom	DNAH9 DYNC1H1	1.44e-03	14	76	2	IPR024317
Domain	Dynein_HC_stalk	DNAH9 DYNC1H1	1.44e-03	14	76	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH9 DYNC1H1	1.44e-03	14	76	2	IPR013602
Domain	DHC_N2	DNAH9 DYNC1H1	1.44e-03	14	76	2	PF08393
Domain	MT	DNAH9 DYNC1H1	1.44e-03	14	76	2	PF12777
Domain	AAA_8	DNAH9 DYNC1H1	1.44e-03	14	76	2	PF12780
Domain	ATPase_dyneun-rel_AAA	DNAH9 DYNC1H1	1.44e-03	14	76	2	IPR011704
Domain	AAA_5	DNAH9 DYNC1H1	1.44e-03	14	76	2	PF07728
Domain	DHC_fam	DNAH9 DYNC1H1	1.66e-03	15	76	2	IPR026983
Domain	Dynein_heavy_dom	DNAH9 DYNC1H1	1.66e-03	15	76	2	IPR004273
Domain	Dynein_heavy	DNAH9 DYNC1H1	1.66e-03	15	76	2	PF03028
Domain	ZZ	HERC2 DMD	2.40e-03	18	76	2	PF00569
Domain	ZF_ZZ_2	HERC2 DMD	2.40e-03	18	76	2	PS50135
Domain	ZF_ZZ_1	HERC2 DMD	2.40e-03	18	76	2	PS01357
Domain	Znf_ZZ	HERC2 DMD	2.67e-03	19	76	2	IPR000433
Domain	ZnF_ZZ	HERC2 DMD	2.67e-03	19	76	2	SM00291
Domain	Ez/rad/moesin-like	RDX FRMD5	3.26e-03	21	76	2	IPR000798
Pubmed	Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.	DST MACF1 DMD	4.50e-08	4	79	3	8954775
Pubmed	A human MAP kinase interactome.	DST NEDD4L CCDC186 SPTBN2 MACF1 AKAP13 POGZ PLEC HERC2 DMD	1.58e-07	486	79	10	20936779
Pubmed	The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.	SPATA31A3 SPATA31A7 SPATA31A5	2.24e-07	6	79	3	20850414
Pubmed	Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.	SPATA31A3 SPATA31A7 SPATA31A5	2.24e-07	6	79	3	25930072
Pubmed	HENA, heterogeneous network-based data set for Alzheimer's disease.	DST MACF1 ZFC3H1 HERC2 DMD DYNC1H1	3.37e-07	120	79	6	31413325
Pubmed	Comparative genomic analysis of the clade B serpin cluster at human chromosome 18q21: amplification within the mouse squamous cell carcinoma antigen gene locus.	SERPINB8 SERPINB13 SERPINB2	1.84e-06	11	79	3	15203215
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	DST ANKRD36 PLEC ZFC3H1 DMD PARP14	4.47e-06	187	79	6	26460568
Pubmed	Stretch-activated calcium channel protein TRPC1 is correlated with the different degrees of the dystrophic phenotype in mdx mice.	TRPC1 DMD	5.09e-06	2	79	2	21900691
Pubmed	Extended tropism of an adenoviral vector does not circumvent the maturation-dependent transducibility of mouse skeletal muscle.	LAMA2 DMD	5.09e-06	2	79	2	10753064
Pubmed	Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.	DST MACF1	5.09e-06	2	79	2	11002341
Pubmed	Analysis of dystrophin in fast- and slow-twitch skeletal muscles from mdx and dy2J mice at different ages.	LAMA2 DMD	5.09e-06	2	79	2	2183046
Pubmed	Quantitative morphology of mast cells in skeletal muscle of normal and genetically dystrophic mice.	LAMA2 DMD	5.09e-06	2	79	2	9066911
Pubmed	Laminin-alpha2 but not -alpha1-mediated adhesion of human (Duchenne) and murine (mdx) dystrophic myotubes is seriously defective.	LAMA2 DMD	5.09e-06	2	79	2	9188790
Pubmed	Complement 3 deficiency and oral prednisolone improve strength and prolong survival of laminin alpha2-deficient mice.	LAMA2 C3	5.09e-06	2	79	2	12044978
Pubmed	Diseased muscles that lack dystrophin or laminin-alpha2 have altered compositions and proliferation of mononuclear cell populations.	LAMA2 DMD	5.09e-06	2	79	2	15817132
Pubmed	Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association.	RDX ROCK1	5.09e-06	2	79	2	9456324
Pubmed	Muscular dystrophies: diseases of the dystrophin-glycoprotein complex.	LAMA2 DMD	5.09e-06	2	79	2	7481760
Pubmed	Muscle fiber growth and necrosis in dystrophic muscles: a comparative study between dy and mdx mice.	LAMA2 DMD	5.09e-06	2	79	2	3440862
Pubmed	Cytoplasmic gamma-actin contributes to a compensatory remodeling response in dystrophin-deficient muscle.	LAMA2 DMD	5.09e-06	2	79	2	16565216
Pubmed	Animal models for muscular dystrophy show different patterns of sarcolemmal disruption.	LAMA2 DMD	5.09e-06	2	79	2	9334342
Pubmed	Genetic analysis of diabetic nephropathy on chromosome 18 in African Americans: linkage analysis and dense SNP mapping.	SERPINB13 NEDD4L SERPINB2	7.50e-06	17	79	3	19690890
Pubmed	Functional proteomics mapping of a human signaling pathway.	DST NEDD4L NELFCD WWP1 MACF1 ROCK1 PLEC HERC2 DYNC1H1	7.95e-06	591	79	9	15231748
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	DST SWAP70 SPTBN2 MACF1 CEP152	1.22e-05	130	79	5	12421765
Pubmed	Cytoplasmic antiproteinase 2 (PI8) and bomapin (PI10) map to the serpin cluster at 18q21.3.	SERPINB8 SERPINB2	1.53e-05	3	79	2	9268635
Pubmed	BPAG1 isoform-b: complex distribution pattern in striated and heart muscle and association with plectin and alpha-actinin.	DST PLEC	1.53e-05	3	79	2	19932097
Pubmed	Expression of the mouse Macf2 gene during inner ear development.	DST MACF1	1.53e-05	3	79	2	12399109
Pubmed	Proinflammatory signals and the loss of lymphatic vessel hyaluronan receptor-1 (LYVE-1) in the early pathogenesis of laminin alpha2-deficient skeletal muscle.	LAMA2 DMD	1.53e-05	3	79	2	20876525
Pubmed	Dystroglycan is not required for localization of dystrophin, syntrophin, and neuronal nitric-oxide synthase at the sarcolemma but regulates integrin alpha 7B expression and caveolin-3 distribution.	LAMA2 DMD	1.53e-05	3	79	2	11741881
Pubmed	Tissue distribution of the dystrophin-related gene product and expression in the mdx and dy mouse.	LAMA2 DMD	1.53e-05	3	79	2	2014247
Pubmed	The Lbc Rho guanine nucleotide exchange factor α-catulin axis functions in serotonin-induced vascular smooth muscle cell mitogenesis and RhoA/ROCK activation.	CTNNAL1 AKAP13	1.53e-05	3	79	2	20696764
Pubmed	Three mouse models of muscular dystrophy: the natural history of strength and fatigue in dystrophin-, dystrophin/utrophin-, and laminin alpha2-deficient mice.	LAMA2 DMD	1.53e-05	3	79	2	11595512
Pubmed	Severe muscular dystrophy in mice that lack dystrophin and alpha7 integrin.	LAMA2 DMD	1.53e-05	3	79	2	16684813
Pubmed	FERM domain-containing protein FRMD5 regulates cell motility via binding to integrin β5 subunit and ROCK1.	ROCK1 FRMD5	1.53e-05	3	79	2	25448675
Pubmed	Regulation of intestinal phosphate cotransporter NaPi IIb by ubiquitin ligase Nedd4-2 and by serum- and glucocorticoid-dependent kinase 1.	NEDD4L SLC34A2	1.53e-05	3	79	2	15044175
Pubmed	Dystrophin-associated proteins are greatly reduced in skeletal muscle from mdx mice.	LAMA2 DMD	1.53e-05	3	79	2	1757468
Pubmed	Interaction of α-catulin with dystrobrevin contributes to integrity of dystrophin complex in muscle.	CTNNAL1 DMD	1.53e-05	3	79	2	22577143
Pubmed	Genetic ablation of complement C3 attenuates muscle pathology in dysferlin-deficient mice.	C3 DMD	1.53e-05	3	79	2	21060153
Pubmed	Overexpression of the cytotoxic T cell (CT) carbohydrate inhibits muscular dystrophy in the dyW mouse model of congenital muscular dystrophy 1A.	LAMA2 DMD	1.53e-05	3	79	2	17591965
Pubmed	Spontaneous opening of the acetylcholine receptor channel in developing muscle cells from normal and dystrophic mice.	LAMA2 DMD	1.53e-05	3	79	2	8568931
Pubmed	Dystroglycan expression in the wild type and mdx mouse neural retina: synaptic colocalization with dystrophin, dystrophin-related protein but not laminin.	LAMA2 DMD	1.53e-05	3	79	2	8568939
Pubmed	TRPC1 binds to caveolin-3 and is regulated by Src kinase - role in Duchenne muscular dystrophy.	TRPC1 DMD	1.53e-05	3	79	2	18544631
Pubmed	Alternative splicing determines the domain structure of WWP1, a Nedd4 family protein.	NEDD4L WWP1	1.53e-05	3	79	2	11779188
Pubmed	Loss of dystrophin and β-sarcoglycan significantly exacerbates the phenotype of laminin α2 chain-deficient animals.	LAMA2 DMD	1.53e-05	3	79	2	24393714
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	DST SPTBN2 KRI1 MACF1 POGZ URB2 PLEC HERC2 DYNC1H1	1.75e-05	653	79	9	22586326
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	DST WWP1 LAMA2 RDX MACF1 PLEC CCDC141 USP1	1.76e-05	497	79	8	23414517
Pubmed	Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.	LRP2 LAMA2 DMD SPICE1	2.13e-05	71	79	4	33541421
Pubmed	Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.	POC1B CEP152 POC5 DYNC1H1 SPICE1	2.14e-05	146	79	5	21399614
Pubmed	Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.	SPATA31A3 SPATA31A7 SPATA31A5	2.21e-05	24	79	3	32212159
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	LSM12 SPTBN2 LRP2 KRI1 CEP152 POC5 PLEC HERC2 LYAR DYNC1H1	2.34e-05	853	79	10	28718761
Pubmed	Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.	MACF1 PLEC HERC2 DYNC1H1	2.79e-05	76	79	4	27542412
Pubmed	System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.	NEDD4L WWP1 HERC2	2.82e-05	26	79	3	26949039
Pubmed	Altered expression of the alpha7beta1 integrin in human and murine muscular dystrophies.	LAMA2 DMD	3.05e-05	4	79	2	9427295
Pubmed	Association of Lbc Rho guanine nucleotide exchange factor with alpha-catenin-related protein, alpha-catulin/CTNNAL1, supports serum response factor activation.	CTNNAL1 AKAP13	3.05e-05	4	79	2	12270917
Pubmed	Role of binding of plectin to the integrin beta4 subunit in the assembly of hemidesmosomes.	DST PLEC	3.05e-05	4	79	2	14668477
Pubmed	Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy.	LAMA2 DMD	3.05e-05	4	79	2	18345011
Pubmed	Loss of β2-spectrin prevents cardiomyocyte differentiation and heart development.	SPTBN2 DMD	3.05e-05	4	79	2	24064296
Pubmed	Muscle-specific BCL2 expression ameliorates muscle disease in laminin {alpha}2-deficient, but not in dystrophin-deficient, mice.	LAMA2 DMD	3.05e-05	4	79	2	15757977
Pubmed	Human eye colour and HERC2, OCA2 and MATP.	SLC34A2 HERC2	3.05e-05	4	79	2	20457063
Pubmed	The involvement of collagen triple helix repeat containing 1 in muscular dystrophies.	LAMA2 DMD	3.05e-05	4	79	2	23274062
Pubmed	The Ubiquitin Ligase Itch and Ubiquitination Regulate BFRF1-Mediated Nuclear Envelope Modification for Epstein-Barr Virus Maturation.	NEDD4L WWP1	3.05e-05	4	79	2	27466427
Pubmed	Bortezomib partially improves laminin α2 chain-deficient muscular dystrophy.	LAMA2 DMD	3.05e-05	4	79	2	24631023
Pubmed	Rho-ROCK-dependent ezrin-radixin-moesin phosphorylation regulates Fas-mediated apoptosis in Jurkat cells.	RDX ROCK1	3.05e-05	4	79	2	18941185
Pubmed	Elevated Expression of Moesin in Muscular Dystrophies.	LAMA2 DMD	3.05e-05	4	79	2	28082118
Pubmed	Plectin 1f scaffolding at the sarcolemma of dystrophic (mdx) muscle fibers through multiple interactions with beta-dystroglycan.	PLEC DMD	3.05e-05	4	79	2	17389230
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	MAPKAP1 CTNNAL1 DST NEDD4L MACF1 ROCK1 DMD	4.96e-05	421	79	7	36976175
Pubmed	EMRE is essential for mitochondrial calcium uniporter activity in a mouse model.	LAMA2 DMD	5.07e-05	5	79	2	32017711
Pubmed	miR-410 and miR-495 Are Dynamically Regulated in Diverse Cardiomyopathies and Their Inhibition Attenuates Pathological Hypertrophy.	LAMA2 DMD	5.07e-05	5	79	2	26999812
Pubmed	Ex vivo stretch reveals altered mechanical properties of isolated dystrophin-deficient hearts.	LAMA2 DMD	5.07e-05	5	79	2	22427904
Pubmed	α-Catulin promotes cancer stemness by antagonizing WWP1-mediated KLF5 degradation in lung cancer.	CTNNAL1 WWP1	5.07e-05	5	79	2	35154481
Pubmed	Differential expression of C-protein isoforms in developing and degenerating mouse striated muscles.	LAMA2 DMD	5.07e-05	5	79	2	10024132
Pubmed	Exacerbated pathology of viral encephalitis in mice with central nervous system-specific autoantibodies.	CD4 C3	5.07e-05	5	79	2	17255324
Pubmed	Complement C3 and marginal zone B cells promote IgG-mediated enhancement of RBC alloimmunization in mice.	CD4 C3	5.07e-05	5	79	2	38618959
Pubmed	Pax7, Pax3 and Mamstr genes are involved in skeletal muscle impaired regeneration of dy2J/dy2J mouse model of Lama2-CMD.	LAMA2 DMD	5.07e-05	5	79	2	31348492
Pubmed	A Nedd4 E3 Ubiquitin Ligase Pathway Inhibits Robo1 Repulsion and Promotes Commissural Axon Guidance across the Midline.	NEDD4L WWP1	5.07e-05	5	79	2	36002265
Pubmed	Identification of new partners of the epithelial sodium channel alpha subunit.	NEDD4L WWP1	5.07e-05	5	79	2	14556380
Pubmed	Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.	TMTC3 CCDC186 WWP1 SGO2 PNPLA8 TTLL1 POGZ LYAR USP1	5.15e-05	750	79	9	11230166
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	POC1B STRN4 SGO2 CEP152 POC5 POGZ HERC2 ESCO1 DYNC1H1 SPICE1 TTC33	5.92e-05	1155	79	11	20360068
Pubmed	Scanning the human proteome for calmodulin-binding proteins.	DST RDX HERC2 CDC37L1	5.92e-05	92	79	4	15840729
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	DST NEDD4L SPTBN2 STRN4 RDX MACF1 ROCK1 HERC2 DYNC1H1 SPICE1	6.47e-05	963	79	10	28671696
Pubmed	Cib2 binds integrin alpha7Bbeta1D and is reduced in laminin alpha2 chain-deficient muscular dystrophy.	LAMA2 DMD	7.60e-05	6	79	2	18611855
Pubmed	Gene expression in temporal lobe epilepsy is consistent with increased release of glutamate by astrocytes.	RDX PLEC	7.60e-05	6	79	2	17515952
Pubmed	Mechanism of ubiquitin chain synthesis employed by a HECT domain ubiquitin ligase.	NEDD4L WWP1	7.60e-05	6	79	2	28461335
Pubmed	Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability.	DST NEDD4L MACF1 PLEC DYNC1H1	7.69e-05	191	79	5	33762435
Pubmed	Proximity interactions among centrosome components identify regulators of centriole duplication.	CEP152 POC5 LYAR SPICE1	8.52e-05	101	79	4	24613305
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	SPTBN2 HERC2 DNAH9 DYNC1H1	9.54e-05	104	79	4	9205841
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	IQCF2 DST NELFCD SPTBN2 STRN4 RDX MACF1 TTLL1 PLEC ZFC3H1 DMD USP1	9.65e-05	1442	79	12	35575683
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	TMTC3 AKAP13 PLEC HERC2 PARP14	1.00e-04	202	79	5	33005030
Pubmed	Inhibition of pulmonary antibacterial defense by interferon-gamma during recovery from influenza infection.	CD4 C3	1.06e-04	7	79	2	18438414
Pubmed	Transmembrane adaptor protein WBP1L regulates CXCR4 signalling and murine haematopoiesis.	NEDD4L WWP1	1.06e-04	7	79	2	31845480
Pubmed	The N terminus of the transmembrane protein BP180 interacts with the N-terminal domain of BP230, thereby mediating keratin cytoskeleton anchorage to the cell surface at the site of the hemidesmosome.	DST PLEC	1.06e-04	7	79	2	10637308
Pubmed	Alpha-dystrobrevin-1 recruits alpha-catulin to the alpha1D-adrenergic receptor/dystrophin-associated protein complex signalosome.	CTNNAL1 DMD	1.06e-04	7	79	2	21115837
Pubmed	Cytoplasmic gamma-actin expression in diverse animal models of muscular dystrophy.	LAMA2 DMD	1.06e-04	7	79	2	17475492
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	LSM12 RNASEH2B DST SGO2 ROCK1 C3 CEP152 SPICE1	1.10e-04	645	79	8	25281560
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	DST MACF1 URB2 PLEC PARP14 DYNC1H1	1.12e-04	332	79	6	37433992
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	DST USP40 STRN4 LRP2 MACF1 PLEC HERC2	1.14e-04	481	79	7	28190767
Pubmed	Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.	CEP152 POGZ URB2 PLEC PARP14 DYNC1H1	1.27e-04	340	79	6	29478914
Pubmed	Update of the human and mouse SERPIN gene superfamily.	SERPINB8 SERPINB13 SERPINB2	1.30e-04	43	79	3	24172014
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	CTNNAL1 SPTBN2 KRI1 ROCK1 POC5 HERC2 DMD USP1 SPICE1 TTC33	1.31e-04	1049	79	10	27880917
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SWAP70 SPTBN2 MACF1 CEP152 ZFC3H1 PTGFRN ESCO1	1.33e-04	493	79	7	15368895
Pubmed	Caveolin-3 deficiency causes muscle degeneration in mice.	LAMA2 DMD	1.41e-04	8	79	2	11115849
Interaction	PCNT interactions	DST SPTBN2 POC1B RDX MACF1 CEP152 PLEC SPICE1	3.49e-06	241	76	8	int:PCNT
Cytoband	Ensembl 112 genes in cytogenetic band chr18q21	SERPINB13 NEDD4L MRO SERPINB2 ST8SIA3	2.91e-05	205	79	5	chr18q21
Cytoband	Ensembl 112 genes in cytogenetic band chr9q12	SPATA31A7 SPATA31A5	8.13e-05	8	79	2	chr9q12
Cytoband	18q21	NEDD4L MRO	4.39e-04	18	79	2	18q21
Cytoband	9p13.1	SPATA31A3 ANKRD18A	7.87e-04	24	79	2	9p13.1
GeneFamily	EF-hand domain containing\|Plakins	DST MACF1 PLEC	1.56e-06	8	56	3	939
GeneFamily	Serpin peptidase inhibitors	SERPINB8 SERPINB13 SERPINB2	2.03e-04	37	56	3	739
GeneFamily	Zinc fingers\|Zinc fingers PARP-type\|Poly(ADP-ribose) polymerases	ZFC3H1 LYAR	9.64e-04	15	56	2	26
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	HERC2 DMD	1.40e-03	18	56	2	91
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	SWAP70 SPTBN2 ROCK1 AKAP13	3.79e-03	206	56	4	682
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	MTIF3 DST TMTC3 CCDC186 WWP1 ROCK1 ANKRD36	6.60e-08	199	79	7	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	MACF1 ROCK1 AKAP13 DDX60L ZFC3H1 PARP14 DYNC1H1	6.83e-08	200	79	7	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	NEDD4L LRP2 SLC34A2 C3 CCDC141 FRMD5	1.16e-06	191	79	6	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	facs-Thymus-Thymus_Epithelium\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA1A KCNK2 LRP2 LAMA2 C3 DMD	1.35e-06	196	79	6	6bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCell	facs-Thymus-Thymus_Epithelium-18m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA1A KCNK2 LRP2 LAMA2 C3 DMD	1.35e-06	196	79	6	c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	KRI1 ANKRD18A CEP152 ANKRD36 ZFC3H1 LYAR	1.39e-06	197	79	6	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	MTIF3 TMTC3 CCDC186 WWP1 RDX ROCK1	1.48e-06	199	79	6	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell	LPS_IL1RA-Endothelial-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CTNNAL1 DST RDX MACF1 PARP14 DYNC1H1	1.52e-06	200	79	6	72ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCell	LPS_IL1RA-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CTNNAL1 DST RDX MACF1 PARP14 DYNC1H1	1.52e-06	200	79	6	5c092b2ecc081b5d04476c56333c338cd89ab984
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CTNNAL1 DST RDX MACF1 PARP14 DYNC1H1	1.52e-06	200	79	6	79e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating-cycling_ventral_progenitors\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	RNASEH2B NEDD4L SGO2 DLX6 USP1	1.31e-05	170	79	5	73601c873b177d5d134618d8e228c51381119f7d
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Differentiating_glia\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CTNNAL1 DST KCNK2 DLX6 FRMD5	1.46e-05	174	79	5	412ccc099028a372b9d953363984c2da54b2187f
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-mesothelial_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SERPINB2 LRP2 SLC34A2 SGO2 C3	1.77e-05	181	79	5	3dcb74b28f93be35ddf4de1937f7e30b25e11927
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SERPINB2 LRP2 SLC34A2 SGO2 C3	1.77e-05	181	79	5	7679a5980011d6dfb1aaca7abf678c29b6f819bb
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	NEDD4L LRP2 SLC34A2 C3 CCDC141	1.91e-05	184	79	5	369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	DST MACF1 C3 AKAP13 TESPA1	1.91e-05	184	79	5	d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	DST LAMA2 AKAP13 DMD CCDC141	1.91e-05	184	79	5	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CTNNAL1 DST LAMA2 DMD FRMD5	2.01e-05	186	79	5	6f88b68735d0f7c9904eb8413e6007910d556185
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TUT4 CD4 MACF1 ESCO1 TESPA1	2.23e-05	190	79	5	91ba66d4b56c59523485b17738e93f14bb00afa4
ToppCell	COVID-19-lung-AT2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NEDD4L SLC34A2 C3 CCDC141 FRMD5	2.23e-05	190	79	5	27a1a86620fe9b5ee930d388b32352206485e6d0
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|RV / Chamber and Cluster_Paper	DST LAMA2 AKAP13 DMD CCDC141	2.23e-05	190	79	5	fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	DST LAMA2 AKAP13 DMD CCDC141	2.29e-05	191	79	5	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CTNNAL1 DST TMTC3 DMD IQCK	2.46e-05	194	79	5	8985095f291c1b54e45f4edece49aa26e8c8b732
ToppCell	Control-Epithelial-ATII\|Epithelial / Disease state, Lineage and Cell class	SLC34A2 MACF1 C3 AKAP13 CCDC141	2.46e-05	194	79	5	a01de094f7bfd099bcbb2f94224690a2efb887b4
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NEDD4L LRP2 SLC34A2 AKAP13 CCDC141	2.52e-05	195	79	5	6617abca0009ad3d8731f515f91ab275f9ea4c40
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NEDD4L LRP2 SLC34A2 AKAP13 CCDC141	2.52e-05	195	79	5	fc0ae145a2118df7cbbc9ac4ca9dc12d26c087c4
ToppCell	COVID-19-Heart-CM_2\|Heart / Disease (COVID-19 only), tissue and cell type	DST LAMA2 AKAP13 DMD CCDC141	2.52e-05	195	79	5	75fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD4+_Memory_T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	CD4 DST WWP1 ANKRD18A TESPA1	2.52e-05	195	79	5	22191d361af136942508f1553ff41a626ed982ad
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NEDD4L SLC34A2 C3 AKAP13 CCDC141	2.59e-05	196	79	5	7e5addaa844e66f8160e05858c341866a80aed23
ToppCell	facs-Skin-Telogen-3m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SERPINB8 DST KCNK2 MACF1 DMD	2.59e-05	196	79	5	90edf61116ffcb4f8b6be3d0a05732d59b0a87d5
ToppCell	facs-Skin-Telogen-3m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SERPINB8 DST KCNK2 MACF1 DMD	2.59e-05	196	79	5	c936014125b2ed5f796221b74acb77b8f8359875
ToppCell	cellseq-Epithelial-Epithelial_Alveolar\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NEDD4L SLC34A2 C3 AKAP13 CCDC141	2.59e-05	196	79	5	a7cbe66ebd8931ef2b8ff26a42afce0ad1c48f17
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NEDD4L SLC34A2 C3 AKAP13 CCDC141	2.59e-05	196	79	5	65e161fd672e37a5d10f28011bb422c4d7042d6a
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CTNNAL1 DST KCNK2 DMD FRMD5	2.65e-05	197	79	5	bb35a2b7320fda92e9cd42f536b7bd54e3a73a32
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CTNNAL1 DST KCNK2 DMD FRMD5	2.65e-05	197	79	5	1018aac22659c081d227d566afa29b1748c18ade
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NEDD4L SLC34A2 C3 AKAP13 CCDC141	2.65e-05	197	79	5	bf10727fbe90b71d2ac60a11711e5f0701b3799d
ToppCell	COVID-19_Mild\|World / Disease condition and Cell class	CD4 AKAP13 DDX60L PARP14 DYNC1H1	2.72e-05	198	79	5	61ceb2245b6cb58e308b999a61d218c89dbc615e
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CTNNAL1 DST KCNK2 DMD FRMD5	2.72e-05	198	79	5	5b9a7b9f53a3d9cf8d6e6a7c1c94514b22cf9fa8
ToppCell	distal-1-Epithelial-Alveolar_Epithelial_Type_2\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NEDD4L LRP2 SLC34A2 C3 CCDC141	2.72e-05	198	79	5	ce9d6b2a93c7b304414ce1b8b1a09562cf581278
ToppCell	Biopsy_Other_PF-Epithelial-AT2\|Biopsy_Other_PF / Sample group, Lineage and Cell type	NEDD4L LRP2 SLC34A2 C3 CCDC141	2.78e-05	199	79	5	9a65acfe9bf500db72142469cf17bf0973540001
ToppCell	Control_saline\|World / Treatment groups by lineage, cell group, cell type	CTNNAL1 DST RDX MACF1 PLEC	2.78e-05	199	79	5	11c9c1779caceb725ecccf3f23b7d4e6dbd1af64
ToppCell	Bronchial-10x5prime-Epithelial-Epi_alveolar\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	NEDD4L LRP2 SLC34A2 C3 CCDC141	2.78e-05	199	79	5	a38a981cffa61c8444a980916de7414e689a1b63
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LRP2 SLC34A2 C3 AKAP13 CCDC141	2.78e-05	199	79	5	2dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CTNNAL1 DST KCNK2 DMD FRMD5	2.78e-05	199	79	5	1761669ec514fdb4175042f11b9a31fa5687fc2b
ToppCell	(01)_IL1RL1+-(2)_GFP_FOXI1\|(01)_IL1RL1+ / shred by cell type by condition	MTIF3 CTNNAL1 CCDC186 ROCK1 ANKRD18A	2.78e-05	199	79	5	a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TUT4 CTNNAL1 DST RDX MACF1	2.85e-05	200	79	5	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	LPS_only-Endothelial\|LPS_only / Treatment groups by lineage, cell group, cell type	CTNNAL1 DST RDX MACF1 PARP14	2.85e-05	200	79	5	81e76508c9050d533853d5fd2f3097b27613d836
ToppCell	Control_saline-Endothelial-Endothelial-Gen_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	TUT4 CTNNAL1 DST RDX MACF1	2.85e-05	200	79	5	3b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_alveolar-AT2\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	NEDD4L LRP2 SLC34A2 C3 CCDC141	2.85e-05	200	79	5	23088edc62bf7d4db890937bfd7925dc316fcc76
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CTNNAL1 DST KCNK2 LAMA2 DMD	2.85e-05	200	79	5	363a8cebf2ace820661bcb87c7941f6671f8e5f3
ToppCell	Bronchial-10x5prime-Epithelial-Epi_alveolar-AT2\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	NEDD4L LRP2 SLC34A2 C3 CCDC141	2.85e-05	200	79	5	b535323e18d9fb0dde1e0026df142c831e48c29f
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TUT4 CTNNAL1 DST RDX MACF1	2.85e-05	200	79	5	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	MACF1 ROCK1 AKAP13 PARP14 DYNC1H1	2.85e-05	200	79	5	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	LPS_only-Endothelial-Endothelial\|LPS_only / Treatment groups by lineage, cell group, cell type	CTNNAL1 DST RDX MACF1 PARP14	2.85e-05	200	79	5	4bb609a284d4e6066f17470a1736076aa4a1f84c
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_activate-7\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SWAP70 SPTBN2 URB2 DMD	7.49e-05	126	79	4	518a6e4919981b556ce6b451a91270dba976bc75
ToppCell	ILEUM-non-inflamed-(3)_MNP-(3)_moDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	TUT4 DST MACF1 AKAP13	9.78e-05	135	79	4	b7a792a7c0c22d8b703509f134115f0e394d7de0
ToppCell	(08)_Brush+PNEC-(2)_GFP_FOXI1\|(08)_Brush+PNEC / shred by cell type by condition	MAPKAP1 MTIF3 CCDC186 ROCK1	1.07e-04	138	79	4	817e3f639604ea95adae01e8685ffaa2e0aff7a8
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-Z\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CD4 ZNF556 C3 PARP14	1.29e-04	145	79	4	9743d68ba8bfef56fd9a979ab357c0e287eb5ae2
ToppCell	lung-Type_II_Pneumocytes\|lung / shred on tissue and cell subclass	SLC34A2 C3 AKAP13 CCDC141	1.36e-04	147	79	4	8a3039de45b8087f8319e2e37329acf7278219b7
ToppCell	TCGA-Uterus-Primary_Tumor-Uterine_Carcinoma-Uterine_Carcinosarcoma\|TCGA-Uterus / Sample_Type by Project: Shred V9	DST CCDC186 POC1B PNPLA8	1.51e-04	151	79	4	2810bfa01bd3016aeba29735eb4a9284792e8aac
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Tall_Cell-1\|TCGA-Thryoid / Sample_Type by Project: Shred V9	SERPINB13 SPATA31A3 SERPINB2 FRMD5	1.71e-04	156	79	4	45a05c7a45a3ec8551818ab67f18b3b9553934c1
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SLC9B1 DMD PTGFRN WARS2	1.75e-04	157	79	4	f896997490bb2eec598c6581f161220e70f9a991
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SLC9B1 DMD PTGFRN WARS2	1.75e-04	157	79	4	14a8516346a89a89f1119b744625bd9844a74a03
ToppCell	Influenza_Severe-CD4+_T_naive\|Influenza_Severe / Disease group and Cell class	ANKRD18A CCDC141 TESPA1 CDC37L1	1.75e-04	157	79	4	287bdc4e455cd0160261a93d13538e0def49fcd4
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SWAP70 C3 AKAP13 PARP14	2.02e-04	163	79	4	a6e272e043859858084b8d4d96fa4ff9e6eca454
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SLC34A2 C3 AKAP13 CCDC141	2.07e-04	164	79	4	b0ed8cb6000ce8bf94444307e4b7b3574fa3fab2
ToppCell	343B-Epithelial_cells-Epithelial-A_(AT2)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	LRP2 SLC34A2 C3 AKAP13	2.07e-04	164	79	4	beaa13a75c3bb72446c85084d75e9fe3f15fd3d4
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SLC34A2 C3 AKAP13 CCDC141	2.07e-04	164	79	4	3aea6207a011ad55a1aeb2ed9fb54d31b23694b5
ToppCell	343B-Epithelial_cells-Epithelial-A_(AT2)\|343B / Donor, Lineage, Cell class and subclass (all cells)	LRP2 SLC34A2 C3 AKAP13	2.07e-04	164	79	4	d005cfd821b87548b075120bffe65a0be9860463
ToppCell	facs-Heart-RV-24m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA1A KCNK2 LAMA2 C3	2.21e-04	167	79	4	3e3d8f6df2feefafad5b44ba0ebf5b5a0fe4ed58
ToppCell	facs-Heart-RV-24m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA1A KCNK2 LAMA2 C3	2.21e-04	167	79	4	3ad9f3122dbe96580f640388ef920ea209fc2349
ToppCell	368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	NEDD4L SPTBN2 LRP2 ANKRD18A	2.27e-04	168	79	4	e870d2e69316406f45112ed0bf324b24f902a99e
ToppCell	368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	NEDD4L SPTBN2 LRP2 ANKRD18A	2.27e-04	168	79	4	403aba73a0f9ffb32252288d075fad8a588ca440
ToppCell	facs-Heart-LV-18m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA1A KCNK2 LAMA2 C3	2.32e-04	169	79	4	849a8f8509c58d65462a09c84d58b6ecdc8934f5
ToppCell	3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CTNNAL1 DST KCNK2 DMD	2.32e-04	169	79	4	2456b3e7776e8a2214972be1b4d66a3ca5480ae0
ToppCell	facs-Heart-RV-18m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA1A SERPINB2 KCNK2 C3	2.37e-04	170	79	4	d7c9a604311974ff87ece43a0f8725a234d262f7
ToppCell	MS-CD8-proli_CD4\|MS / Condition, Cell_class and T cell subcluster	CTNNAL1 TMTC3 STRN4 SPICE1	2.48e-04	172	79	4	0b6dd257110b3f17fa71ab18a165b091a9d5ae9a
ToppCell	droplet-Lung-1m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD4 TRPC1 CCDC141 TESPA1	2.48e-04	172	79	4	30f4979abf0218618a56afb06aa6afc23ad838ec
ToppCell	367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SERPINB13 SERPINB2 LRP2 ANKRD18A	2.53e-04	173	79	4	3d7c281a1a9f183a5a861d1a9c7b50d216535893
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST MACF1 AKAP13 ZFC3H1	2.53e-04	173	79	4	869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST MACF1 AKAP13 ZFC3H1	2.53e-04	173	79	4	0672bd8a4a9d18af343d01f09253fb3388896c10
ToppCell	facs-Brain_Myeloid-Cerebellum-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST MACF1 AKAP13 ZFC3H1	2.53e-04	173	79	4	870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCell	367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SERPINB13 SERPINB2 LRP2 ANKRD18A	2.53e-04	173	79	4	3aa90578371039f81b7c6fa873ec70f8f2bc7dfa
ToppCell	5'-GW_trimst-2-LymphNode-Neuronal-Glial_immature\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CTNNAL1 LAMA2 DMD FRMD5	2.59e-04	174	79	4	c9d4e375dedd2b099a9ed70ec38ff35bbb0ce48a
ToppCell	5'-GW_trimst-2-LymphNode-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CTNNAL1 LAMA2 DMD FRMD5	2.59e-04	174	79	4	1463c98f8f519dd030587abbdbeb1b4e1bca5dd1
ToppCell	5'-GW_trimst-2-LymphNode-Neuronal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CTNNAL1 LAMA2 DMD FRMD5	2.59e-04	174	79	4	d421c0069d24cb560a3a429929e3cd1eceaeabcf
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DST LAMA2 MACF1 DMD	2.65e-04	175	79	4	1799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST MACF1 AKAP13 ZFC3H1	2.65e-04	175	79	4	1ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCell	facs-Marrow-B-cells-24m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP2 LAMA2 ANKRD36 DNAH9	2.65e-04	175	79	4	887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCell	facs-Heart-RV-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA1A SERPINB2 KCNK2 C3	2.70e-04	176	79	4	c0a084f7a8645262d61971f094689e02bf15b113
ToppCell	facs-Heart-RV-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA1A SERPINB2 KCNK2 C3	2.70e-04	176	79	4	cccf9201f6e2da7524b911a5961d3b227edab222
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MACF1 PNPLA8 DMD ESCO1	2.70e-04	176	79	4	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	facs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA1A KCNK2 LAMA2 C3	2.70e-04	176	79	4	fee4e0f32aaf77294040c7af6c1f503571750d43
ToppCell	facs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA1A KCNK2 LAMA2 C3	2.70e-04	176	79	4	f25251abd4ef9fb077a978f9f9f658af58e4e0d2
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC186 LAMA2 DMD ST8SIA3	2.76e-04	177	79	4	1dc69c661e70e7e22bd9d7cf953eb638da9fd43c
ToppCell	PCW_13-14-Neuronal-Neuronal_postreplicative-neuro_NA\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	KCNK2 DLX6 ST8SIA3 FRMD5	2.76e-04	177	79	4	8c78f7de091f16e86e326a73c9f1429e0232821f
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC186 LAMA2 DMD ST8SIA3	2.76e-04	177	79	4	426a9845df7fd13b02e744532c336c60bc4d4a22
ToppCell	3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CTNNAL1 DST LAMA2 DMD	2.95e-04	180	79	4	b294f9db1e2ff51c94cde64fae4c2b057c0030a1
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	NEDD4L LRP2 SLC34A2 CCDC141	2.95e-04	180	79	4	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CTNNAL1 LAMA2 DMD FRMD5	2.95e-04	180	79	4	38490017dd590e3fcfa7e88d8d15235d55f90cf1
Computational	Neighborhood of BMPR2	MACF1 POGZ HERC2 DYNC1H1 IQCK	2.62e-05	85	45	5	GCM_BMPR2
Drug	plakin	DST SPTBN2 MACF1 PLEC DMD DYNC1H1	3.24e-07	82	76	6	CID000018752
Disease	Duchenne and Becker Muscular Dystrophy	CD4 DMD	6.34e-05	5	75	2	C3542021
Disease	Becker Muscular Dystrophy	CD4 DMD	6.34e-05	5	75	2	C0917713
Disease	Lissencephaly	TMTC3 MACF1	9.50e-05	6	75	2	C0266463
Disease	Muscular Dystrophy, Duchenne	CD4 DMD	9.50e-05	6	75	2	C0013264
Disease	epidermolysis bullosa simplex (is_implicated_in)	DST PLEC	1.33e-04	7	75	2	DOID:4644 (is_implicated_in)
Disease	Periventricular Nodular Heterotopia	NEDD4L TMTC3	1.33e-04	7	75	2	C1868720
Disease	left ventricular ejection fraction measurement	NEDD4L PLEC CCDC141	1.46e-04	40	75	3	EFO_0008373
Disease	Muscular Dystrophy	LAMA2 DMD	1.77e-04	8	75	2	C0026850
Disease	muscular dystrophy (implicated_via_orthology)	LAMA2 DMD	1.30e-03	21	75	2	DOID:9884 (implicated_via_orthology)
Disease	level of Phosphatidylcholine (16:1_18:2) in blood serum	ROCK1 ESCO1	1.30e-03	21	75	2	OBA_2045083
Disease	osteoarthritis, hip	SPTBN2 PLEC HERC2	1.68e-03	92	75	3	EFO_1000786
Disease	psychosis predisposition measurement	MTIF3 CCDC141	1.99e-03	26	75	2	EFO_0008337
Disease	electrocardiography	USP40 PLEC ZFC3H1 CCDC141 WARS2 FRMD5	2.31e-03	530	75	6	EFO_0004327
Disease	retinal degeneration (biomarker_via_orthology)	C3 DMD	2.31e-03	28	75	2	DOID:8466 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
VKTQHWKKIEKFTAQ	URB2	651	Q14146
NSHVIKVKWAQNKLK	CCDC186	386	Q7Z3E2
KVNWKKSKVTSIVQE	CEP152	516	O94986
NLNETWTSKKKLFQV	ANKRD18A	651	Q8IVF6
WSRIIDSKFLKQQKK	AKAP13	1976	Q12802
NKKNKLTQSKIWDVV	C3	606	P01024
QKQSAWKVIFKKKVS	ANKRD36	616	A6QL64
VQKKTFTKWVNAQFS	DMD	16	P11532
CKKSHQSKKWRIQAQ	C3orf22	6	Q8N5N4
TQVKIWFQNKRSKFK	DLX6	91	P56179
QVKIFWAKQEQKVKC	IQCK	256	Q8N0W5
STWLKLNKKVTQQDV	RDX	56	P35241
LKKVWKVWRSVVQKQ	POC5	281	Q8NA72
HKTIKDCKWQEKNIV	LSM12	121	Q3MHD2
VVETWKKNKRVSINK	NELFCD	366	Q8IXH7
RTVFQENVKVKWKSS	HERC2	156	O95714
KVVQTNCKNWAVTKT	IHO1	351	Q8IYA8
TIKTNWDTFNKQVKE	DST	4931	Q03001
KGKRENKVCVSTWQK	ATXN8OS	156	P0DMR3
KTVKPKWRNVTQEKS	KIAA1109	631	Q2LD37
KVEDTFIKWNVSQTK	KCNK2	206	O95069
TNWIKNGQVKKVKRV	DDX60L	1061	Q5H9U9
DLDTKTKQIQQWIKK	MTIF3	171	Q9H2K0
TKQIQQWIKKKHLVQ	MTIF3	176	Q9H2K0
KAQNSWKKRQVFKSL	KRI1	576	Q8N9T8
KWKSFTLSRIQKQAN	LAMA2	2421	P24043
KWKKFFTSQVKQTRD	MRO	166	Q9BYG7
QVTKWNLFKRKSKQT	LRP2	4576	P98164
KTIKIWDTTNKQCVN	POC1B	166	Q8TC44
RDRVQKKTFTKWVNK	MACF1	76	Q9UPN3
KLFWPKIKKVNVQVS	PARP14	691	Q460N5
KRVHFIKWNEVTKLK	FRMD5	236	Q7Z6J6
KQQWAAFKEQLKKTS	CCDC141	681	Q6ZP82
ISVWIQAQSKKTKSI	CTNNAL1	361	Q9UBT7
NTWKFIIKQSLKHQS	C1orf112	181	Q9NSG2
KKSIQFHWKNSNQIK	CD4	46	P01730
KTHKGDIKQQAWIQK	LYAR	66	Q9NX58
ESIEWKTLQKKKQQK	IQCF2	21	Q8IXL9
RWVKQTNTEKKASVV	DYNC1H1	4591	Q14204
INSSAKKNSNWTKIK	ESCO1	381	Q5FWF5
EKWNNIKKVAITVKQ	DNAH9	1196	Q9NYC9
SQIKIWFQNKRAKIK	EN2	286	P19622
KQKEFVKSSVACKWN	CDC37L1	56	Q7L3B6
RKKINSWVKTQTKGK	SERPINB2	166	P05120
KTTLQKINDWIKLKT	PNPLA8	756	Q9NP80
TKQRNNSWVKSKDVF	PTGFRN	521	Q9P2B2
QWKAKTTKQKHDGTV	WARS2	141	Q9UGM6
VCIKRTVKNFLHKKW	POGZ	1266	Q7Z3K3
NIKQIFQWIFSKKKS	SPATA31A7	1166	Q8IWB4
SKIWTTKNQKGRKVA	POT1	421	Q9NUX5
NQKASTKFWIKQKPI	MAPKAP1	416	Q9BPZ7
KKGTKFTTKWQESHQ	ST8SIA3	341	O43173
SKINKLRNKVNWKTE	SGO2	901	Q562F6
KAWTNSEKLTKSKVQ	SERPINB8	251	P50452
VKKKKTSVKQEWDNT	SPICE1	21	Q8N0Z3
KSLVKIWCKTFTNKT	SLC34A2	296	O95436
TSKGKVKRQNSLKEW	TRPC1	706	P48995
QVKFKFQSSNRVWKK	PLA1A	396	Q53H76
NIKQIFQWIFSKKKS	SPATA31A3	1166	Q5VYP0
KERNKGQKKSLSVWQ	MLN	41	P12872
EAVQKKTFTKWVNSH	SPTBN2	56	O15020
EKTLKWLEKKVNQTV	RNASEH2B	161	Q5TBB1
NIKQIFQWIFSKKKS	SPATA31A5	1166	Q5VU36
KKINSWVESKTNEKI	SERPINB13	146	Q9UIV8
SLKQKIEKFTRKNIW	ZNF556	66	Q9HAH1
KAFSWVSVLNKHKKI	ZNF728	571	P0DKX0
TKWSQEKMKVQKIIT	SLC9B1	356	Q4ZJI4
QKKTFTKWVNKHLIK	PLEC	181	Q15149
KKKIKWIGLTTNSAQ	TFDP3	181	Q5H9I0
SQDEQKKWVTHLVKK	ROCK1	1301	Q13464
TLKLWNLQKAVTAKK	STRN4	461	Q9NRL3
KKKKQEWIQAIHSTI	SWAP70	291	Q9UH65
KVKSLDLSITQQKWK	TESPA1	451	A2RU30
HGWQKISTKSVFKKL	TMTC3	391	Q6ZXV5
QVTVSSAKLKRKKNW	WWP1	21	Q9H0M0
QKKLLTTFEKQWTSK	TUT4	1211	Q5TAX3
PISSWNQQITKRKKK	USP40	1131	Q9NVE5
TAKQALRKQQTKAWK	ZFC3H1	426	O60293
SQKKSRVKINWLKSA	USP1	331	O94782
INKLSQIKKWSRDSK	TTLL1	151	O95922
WKRKIGEKVSKVTSQ	TTC33	6	Q6PID6
VQTKTIKKTLNPKWN	NEDD4L	61	Q96PU5