Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	D-dopachrome decarboxylase activity	DDT DDTL	2.90e-05	2	108	2	GO:0033981
GeneOntologyMolecularFunction	cannabinoid receptor activity	CNR1 CNR2	8.66e-05	3	108	2	GO:0004949
GeneOntologyMolecularFunction	phenylpyruvate tautomerase activity	DDT DDTL	8.66e-05	3	108	2	GO:0050178
GeneOntologyMolecularFunction	SUMO ligase activity	RGPD4 RGPD1 RGPD3	1.64e-04	20	108	3	GO:0061665
GeneOntologyMolecularFunction	intramolecular oxidoreductase activity, interconverting keto- and enol-groups	DDT DDTL	1.73e-04	4	108	2	GO:0016862
GeneOntologyMolecularFunction	small GTPase binding	RGPD4 STRN3 DOCK9 RGPD1 XPO4 UNC13D INF2 RGPD3	3.57e-04	321	108	8	GO:0031267
GeneOntologyMolecularFunction	GTPase binding	RGPD4 STRN3 DOCK9 RGPD1 XPO4 UNC13D INF2 RGPD3	7.60e-04	360	108	8	GO:0051020
GeneOntologyMolecularFunction	SUMO transferase activity	RGPD4 RGPD1 RGPD3	9.65e-04	36	108	3	GO:0019789
GeneOntologyBiologicalProcess	positive regulation of glucokinase activity	RGPD4 RGPD1 RGPD3	1.11e-05	9	107	3	GO:0033133
GeneOntologyBiologicalProcess	positive regulation of hexokinase activity	RGPD4 RGPD1 RGPD3	1.59e-05	10	107	3	GO:1903301
GeneOntologyBiologicalProcess	regulation of glucokinase activity	RGPD4 RGPD1 RGPD3	3.74e-05	13	107	3	GO:0033131
GeneOntologyBiologicalProcess	regulation of hexokinase activity	RGPD4 RGPD1 RGPD3	4.74e-05	14	107	3	GO:1903299
GeneOntologyCellularComponent	cytoplasmic periphery of the nuclear pore complex	RGPD4 RGPD1 RGPD3	7.17e-06	8	107	3	GO:1990723
GeneOntologyCellularComponent	nuclear pore cytoplasmic filaments	RGPD4 RGPD1 RGPD3	1.52e-05	10	107	3	GO:0044614
GeneOntologyCellularComponent	annulate lamellae	RGPD4 RGPD1 RGPD3	4.56e-05	14	107	3	GO:0005642
GeneOntologyCellularComponent	perinuclear region of cytoplasm	CALCOCO2 RGPD4 AFTPH RGPD1 FSD2 TEK FAT1 KLHL7 INF2 PDE8B PAFAH1B1 RGPD3 OSBPL6 FMN2 ROS1	8.15e-05	934	107	15	GO:0048471
GeneOntologyCellularComponent	inclusion body	RGPD4 MIOX RGPD1 PSMC4 RGPD3	9.95e-05	90	107	5	GO:0016234
GeneOntologyCellularComponent	nuclear pore nuclear basket	RGPD4 RGPD1 RGPD3	1.01e-04	18	107	3	GO:0044615
GeneOntologyCellularComponent	nuclear inclusion body	RGPD4 RGPD1 RGPD3	1.40e-04	20	107	3	GO:0042405
GeneOntologyCellularComponent	SUMO ligase complex	RGPD4 RGPD1 RGPD3	1.62e-04	21	107	3	GO:0106068
MousePheno	abnormal nervous system development	KRAS NCALD KMT2B ROR1 DYNC2I1 GXYLT1 DZIP1 OPA1 OVOL2 ADGB GMNC CSDE1 FAT1 NAMPT MTOR PAFAH1B1 VRTN HYDIN CNR1	3.73e-05	1257	77	19	MP:0003861
MousePheno	abnormal brain development	KRAS NCALD DYNC2I1 GXYLT1 OPA1 OVOL2 ADGB GMNC FAT1 NAMPT MTOR PAFAH1B1 HYDIN	4.09e-05	638	77	13	MP:0000913
Domain	GCC2_Rab_bind	RGPD4 RGPD1 RGPD3	6.47e-06	7	108	3	IPR032023
Domain	Rab_bind	RGPD4 RGPD1 RGPD3	6.47e-06	7	108	3	PF16704
Domain	-	RGPD4 RGPD1 RGPD3	2.19e-05	10	108	3	1.10.220.60
Domain	Grip	RGPD4 RGPD1 RGPD3	3.00e-05	11	108	3	SM00755
Domain	GRIP	RGPD4 RGPD1 RGPD3	3.00e-05	11	108	3	PF01465
Domain	Cnbnoid_rcpt	CNR1 CNR2	3.31e-05	2	108	2	IPR002230
Domain	ZINC_FINGER_C2H2_2	ZNF658 ZNF280C ZBTB8B ZNF215 ZNF275 DZIP1 ZNF284 OVOL2 ZNF800 ZNF620 ZFHX3 ZNF761 ZNF350 ZNF615 ZNF598	3.92e-05	775	108	15	PS50157
Domain	Ran_BP1	RGPD4 RGPD1 RGPD3	3.98e-05	12	108	3	PF00638
Domain	GRIP_dom	RGPD4 RGPD1 RGPD3	3.98e-05	12	108	3	IPR000237
Domain	GRIP	RGPD4 RGPD1 RGPD3	3.98e-05	12	108	3	PS50913
Domain	RANBD1	RGPD4 RGPD1 RGPD3	3.98e-05	12	108	3	PS50196
Domain	ZINC_FINGER_C2H2_1	ZNF658 ZNF280C ZBTB8B ZNF215 ZNF275 DZIP1 ZNF284 OVOL2 ZNF800 ZNF620 ZFHX3 ZNF761 ZNF350 ZNF615 ZNF598	4.03e-05	777	108	15	PS00028
Domain	RanBD	RGPD4 RGPD1 RGPD3	5.16e-05	13	108	3	SM00160
Domain	Ran_bind_dom	RGPD4 RGPD1 RGPD3	5.16e-05	13	108	3	IPR000156
Domain	Znf_C2H2	ZNF658 ZNF280C ZBTB8B ZNF215 ZNF275 DZIP1 ZNF284 OVOL2 ZNF800 ZNF620 ZFHX3 ZNF761 ZNF350 ZNF615 ZNF598	6.03e-05	805	108	15	IPR007087
Domain	ZnF_C2H2	ZNF658 ZNF280C ZBTB8B ZNF215 ZNF275 DZIP1 ZNF284 OVOL2 ZNF800 ZNF620 ZFHX3 ZNF761 ZNF350 ZNF615 ZNF598	6.29e-05	808	108	15	SM00355
Domain	Macrophage_inhib_fac	DDT DDTL	9.90e-05	3	108	2	PD004816
Domain	Macrophage_inhib_fac_CS	DDT DDTL	9.90e-05	3	108	2	IPR019829
Domain	Macrophage_inhib_fac	DDT DDTL	9.90e-05	3	108	2	IPR001398
Domain	Tautomerase/MIF_sf	DDT DDTL	9.90e-05	3	108	2	IPR014347
Domain	MIF	DDT DDTL	9.90e-05	3	108	2	PS01158
Domain	MIF	DDT DDTL	9.90e-05	3	108	2	PF01187
Domain	Znf_C2H2-like	ZNF658 ZNF280C ZBTB8B ZNF215 DZIP1 ZNF284 OVOL2 ZNF800 ZNF620 ZFHX3 ZNF761 ZNF350 ZNF615 ZNF598	1.98e-04	796	108	14	IPR015880
Domain	Munc13_dom-2	UNC13D UNC13A	3.28e-04	5	108	2	IPR014772
Domain	Membr_traf_MHD	UNC13D UNC13A	3.28e-04	5	108	2	PF10540
Domain	MHD2	UNC13D UNC13A	3.28e-04	5	108	2	PS51259
Domain	Munc13_subgr_dom-2	UNC13D UNC13A	3.28e-04	5	108	2	IPR019558
Domain	FAT	TRRAP MTOR	4.89e-04	6	108	2	PS51189
Domain	FATC	TRRAP MTOR	4.89e-04	6	108	2	PS51190
Domain	FAT	TRRAP MTOR	4.89e-04	6	108	2	PF02259
Domain	PIK-rel_kinase_FAT	TRRAP MTOR	4.89e-04	6	108	2	IPR003151
Domain	FATC_dom	TRRAP MTOR	4.89e-04	6	108	2	IPR003152
Domain	PIK_FAT	TRRAP MTOR	4.89e-04	6	108	2	IPR014009
Domain	FATC	TRRAP MTOR	4.89e-04	6	108	2	SM01343
Domain	-	ZNF658 ZBTB8B ZNF215 DZIP1 ZNF284 OVOL2 ZNF800 ZNF620 ZFHX3 ZNF761 ZNF350 ZNF615	5.56e-04	679	108	12	3.30.160.60
Domain	zf-C2H2	ZNF658 ZBTB8B ZNF215 ZNF275 DZIP1 ZNF284 OVOL2 ZNF620 ZFHX3 ZNF761 ZNF350 ZNF615	6.66e-04	693	108	12	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	ZNF658 ZBTB8B ZNF215 DZIP1 ZNF284 OVOL2 ZNF800 ZNF620 ZFHX3 ZNF761 ZNF350 ZNF615	6.74e-04	694	108	12	IPR013087
Domain	DUF1041	UNC13D UNC13A	6.83e-04	7	108	2	PF06292
Domain	Munc13_1	UNC13D UNC13A	6.83e-04	7	108	2	IPR014770
Domain	CAPS_dom	UNC13D UNC13A	6.83e-04	7	108	2	IPR010439
Domain	MHD1	UNC13D UNC13A	6.83e-04	7	108	2	PS51258
Domain	KRAB	ZNF658 ZNF215 ZNF275 ZNF284 ZNF620 ZNF761 ZNF350 ZNF615	1.12e-03	358	108	8	PS50805
Domain	KRAB	ZNF658 ZNF215 ZNF275 ZNF284 ZNF620 ZNF761 ZNF350 ZNF615	1.12e-03	358	108	8	PF01352
Domain	KRAB	ZNF658 ZNF215 ZNF275 ZNF284 ZNF620 ZNF761 ZNF350 ZNF615	1.36e-03	369	108	8	SM00349
Domain	KRAB	ZNF658 ZNF215 ZNF275 ZNF284 ZNF620 ZNF761 ZNF350 ZNF615	1.39e-03	370	108	8	IPR001909
Domain	-	HSPH1 HSPA6	2.11e-03	12	108	2	2.60.34.10
Domain	HSP70_peptide-bd	HSPH1 HSPA6	2.11e-03	12	108	2	IPR029047
Domain	-	HSPH1 HSPA6	2.48e-03	13	108	2	1.20.1270.10
Domain	Heat_shock_70_CS	HSPH1 HSPA6	2.48e-03	13	108	2	IPR018181
Domain	HSP70_C	HSPH1 HSPA6	2.48e-03	13	108	2	IPR029048
Domain	FH2	INF2 FMN2	3.31e-03	15	108	2	PS51444
Domain	FH2_Formin	INF2 FMN2	3.31e-03	15	108	2	IPR015425
Domain	FH2	INF2 FMN2	3.31e-03	15	108	2	PF02181
Domain	FH2	INF2 FMN2	3.31e-03	15	108	2	SM00498
Domain	FBOX	FBXL8 SKP2 FBXO30	3.38e-03	52	108	3	SM00256
Domain	ARM-type_fold	PDS5B DOCK9 XPO4 TRRAP INF2 MTOR NIPBL	3.56e-03	339	108	7	IPR016024
Domain	-	TRRAP MTOR	3.77e-03	16	108	2	1.10.1070.11
Domain	HSP70	HSPH1 HSPA6	3.77e-03	16	108	2	PF00012
Domain	PI3Kc	TRRAP MTOR	3.77e-03	16	108	2	SM00146
Domain	VWA	COL20A1 COL22A1 VWA3B	4.17e-03	56	108	3	PF00092
Domain	HSP70_2	HSPH1 HSPA6	4.26e-03	17	108	2	PS00329
Domain	HSP70_3	HSPH1 HSPA6	4.26e-03	17	108	2	PS01036
Domain	HSP70_1	HSPH1 HSPA6	4.26e-03	17	108	2	PS00297
Domain	Laminin_G	COL20A1 COL22A1 FAT1	4.61e-03	58	108	3	IPR001791
Domain	PI3/4_kinase_cat_dom	TRRAP MTOR	4.77e-03	18	108	2	IPR000403
Domain	PI3_PI4_kinase	TRRAP MTOR	4.77e-03	18	108	2	PF00454
Domain	PI3_4_KINASE_3	TRRAP MTOR	4.77e-03	18	108	2	PS50290
Domain	PI3_4_KINASE_1	TRRAP MTOR	4.77e-03	18	108	2	PS00915
Domain	PI3_4_KINASE_2	TRRAP MTOR	4.77e-03	18	108	2	PS00916
Domain	Hsp_70_fam	HSPH1 HSPA6	4.77e-03	18	108	2	IPR013126
Pubmed	Comparative evaluation of cannabinoid receptors, apelin and S100A6 protein in the heart of women of different age groups.	ACE CNR1 CNR2	1.26e-07	4	111	3	30286717
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	PDS5B DOCK9 HSPH1 PSMC4 CHD9 TRRAP OPA1 DNAH12 TIAL1 TBL2 HYDIN	5.95e-07	497	111	11	36774506
Pubmed	Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2.	RGPD4 RGPD1 RGPD3	1.10e-06	7	111	3	9037092
Pubmed	Complex genomic rearrangements lead to novel primate gene function.	RGPD4 RGPD1 RGPD3	1.10e-06	7	111	3	15710750
Pubmed	Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.	RGPD4 RGPD1 RGPD3	1.10e-06	7	111	3	11353387
Pubmed	Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons.	RGPD4 RGPD1 RGPD3	1.10e-06	7	111	3	30944974
Pubmed	Nucleoporin Nup358 drives the differentiation of myeloid-biased multipotent progenitors by modulating HDAC3 nuclear translocation.	RGPD4 RGPD1 RGPD3	1.10e-06	7	111	3	38838144
Pubmed	Retina-specifically expressed novel subtypes of bovine cyclophilin.	RGPD4 RGPD1 RGPD3	1.10e-06	7	111	3	7559465
Pubmed	Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate.	RGPD4 RGPD1 RGPD3	1.10e-06	7	111	3	17372272
Pubmed	Proteostatic Remodeling of Small Heat Shock Chaperones─Crystallins by Ran-Binding Protein 2─and the Peptidyl-Prolyl cis-trans Isomerase and Chaperone Activities of Its Cyclophilin Domain.	RGPD4 RGPD1 RGPD3	1.10e-06	7	111	3	38657106
Pubmed	Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.	RGPD4 RGPD1 RGPD3	1.10e-06	7	111	3	21205196
Pubmed	Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons.	RGPD4 RGPD1 RGPD3	1.10e-06	7	111	3	18949001
Pubmed	Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.	RGPD4 RGPD1 RGPD3	1.10e-06	7	111	3	25187515
Pubmed	Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex.	RGPD4 RGPD1 RGPD3	1.10e-06	7	111	3	8603673
Pubmed	Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).	RGPD4 RGPD1 RGPD3	1.10e-06	7	111	3	26632511
Pubmed	Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.	RGPD4 RGPD1 RGPD3	1.10e-06	7	111	3	24403063
Pubmed	Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.	RGPD4 RGPD1 RGPD3	1.10e-06	7	111	3	23818861
Pubmed	Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.	RGPD4 RGPD1 RGPD3	1.10e-06	7	111	3	23536549
Pubmed	Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization.	RGPD4 RGPD1 RGPD3	1.10e-06	7	111	3	12191015
Pubmed	Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).	RGPD4 RGPD1 RGPD3	1.10e-06	7	111	3	22821000
Pubmed	Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress.	RGPD4 RGPD1 RGPD3	1.10e-06	7	111	3	20682751
Pubmed	The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.	RGPD4 RGPD1 RGPD3	1.75e-06	8	111	3	21670213
Pubmed	Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis.	RGPD4 RGPD1 RGPD3	1.75e-06	8	111	3	27412403
Pubmed	Mice lacking Ran binding protein 1 are viable and show male infertility.	RGPD4 RGPD1 RGPD3	1.75e-06	8	111	3	21310149
Pubmed	The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2.	RGPD4 RGPD1 RGPD3	1.75e-06	8	111	3	22262462
Pubmed	Zap70 and downstream RanBP2 are required for the exact timing of the meiotic cell cycle in oocytes.	RGPD4 RGPD1 RGPD3	1.75e-06	8	111	3	28745977
Pubmed	Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.	RGPD4 RGPD1 RGPD3	2.62e-06	9	111	3	18394993
Pubmed	Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes.	RGPD4 RGPD1 RGPD3	2.62e-06	9	111	3	28100513
Pubmed	Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function.	RGPD4 RGPD1 RGPD3	2.62e-06	9	111	3	17887960
Pubmed	The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain.	RGPD4 RGPD1 RGPD3	2.62e-06	9	111	3	11553612
Pubmed	The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1.	RGPD4 RGPD1 RGPD3	2.62e-06	9	111	3	10601307
Pubmed	The cyclophilin-like domain mediates the association of Ran-binding protein 2 with subunits of the 19 S regulatory complex of the proteasome.	RGPD4 RGPD1 RGPD3	2.62e-06	9	111	3	9733766
Pubmed	Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2.	RGPD4 RGPD1 RGPD3	2.62e-06	9	111	3	28877029
Pubmed	The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes.	RGPD4 RGPD1 RGPD3	3.74e-06	10	111	3	27160050
Pubmed	Parkin ubiquitinates and promotes the degradation of RanBP2.	RGPD4 RGPD1 RGPD3	3.74e-06	10	111	3	16332688
Pubmed	Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin.	RGPD4 RGPD1 RGPD3	3.74e-06	10	111	3	8857542
Pubmed	Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability.	RGPD4 RGPD1 RGPD3	3.74e-06	10	111	3	21859863
Pubmed	RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism.	RGPD4 RGPD1 RGPD3	5.12e-06	11	111	3	17069463
Pubmed	An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age.	RGPD4 RGPD1 RGPD3	5.12e-06	11	111	3	35771867
Pubmed	T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1.	RGPD4 RGPD1 RGPD3	5.12e-06	11	111	3	34110283
Pubmed	Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.	RGPD4 RGPD1 RGPD3	8.84e-06	13	111	3	31427429
Pubmed	The clinical and pathological significance of increased expression of the cannabinoid receptors CB-1R and CB-2R in patients with papillary thyroid carcinomas compared to benign thyroid lesions.	CNR1 CNR2	1.01e-05	2	111	2	37700679
Pubmed	The effects of targeted deletion of cannabinoid receptors CB1 and CB2 on intranasal sensitization and challenge with adjuvant-free ovalbumin.	CNR1 CNR2	1.01e-05	2	111	2	20190202
Pubmed	Association of cannabinoid receptor genes (CNR1 and CNR2) polymorphisms and panic disorder.	CNR1 CNR2	1.01e-05	2	111	2	32114795
Pubmed	Noncanonical Activity of Endocannabinoids and Their Receptors in Central and Peripheral Synapses.	CNR1 CNR2	1.01e-05	2	111	2	34284706
Pubmed	MECHANISMS IN ENDOCRINOLOGY: Endocannabinoids and metabolism: past, present and future.	CNR1 CNR2	1.01e-05	2	111	2	28246151
Pubmed	Roles of cannabinoid receptors type 1 and 2 on the retinal function of adult mice.	CNR1 CNR2	1.01e-05	2	111	2	24255040
Pubmed	Cannabinoid receptors as novel targets for the treatment of melanoma.	CNR1 CNR2	1.01e-05	2	111	2	17065222
Pubmed	Roles of cannabinoid CB1 and CB2 receptors in the modulation of psychostimulant responses.	CNR1 CNR2	1.01e-05	2	111	2	35993329
Pubmed	Role of CB1 and CB2 cannabinoid receptors in the development of joint pain induced by monosodium iodoacetate.	CNR1 CNR2	1.01e-05	2	111	2	23199705
Pubmed	Involvement of cannabinoid receptors in peripheral and spinal morphine analgesia.	CNR1 CNR2	1.01e-05	2	111	2	24365460
Pubmed	Coordination of microtubule acetylation and the actin cytoskeleton by formins.	INF2 FMN2	1.01e-05	2	111	2	29947928
Pubmed	Antinociceptive effects of the non-selective cannabinoid receptor agonist CP 55,940 are absent in CB1(-/-) and not CB2(-/-) mice in models of acute and persistent pain.	CNR1 CNR2	1.01e-05	2	111	2	19538975
Pubmed	Hepatic expression of endocannabinoid receptors and their novel polymorphisms in primary biliary cirrhosis.	CNR1 CNR2	1.01e-05	2	111	2	19730968
Pubmed	Role of cannabinoid receptors in alcoholic hepatic injury: steatosis and fibrogenesis are increased in CB2 receptor-deficient mice and decreased in CB1 receptor knockouts.	CNR1 CNR2	1.01e-05	2	111	2	21645218
Pubmed	Inhibitory effect of synthetic cannabinoids on cytokine production in rheumatoid fibroblast-like synoviocytes.	CNR1 CNR2	1.01e-05	2	111	2	18799087
Pubmed	Distribution of cannabinoid receptor 1 (CB1) and 2 (CB2) on sensory nerve fibers and adnexal structures in human skin.	CNR1 CNR2	1.01e-05	2	111	2	15927811
Pubmed	CB1 cannabinoid receptor drives oocyte maturation and embryo development via PI3K/Akt and MAPK pathways.	CNR1 CNR2	1.01e-05	2	111	2	28428264
Pubmed	Expression pattern of the cannabinoid receptor genes in the frontal cortex of mood disorder patients and mice selectively bred for high and low fear.	CNR1 CNR2	1.01e-05	2	111	2	22534181
Pubmed	CB1 and CB2 cannabinoid receptors differentially regulate the production of reactive oxygen species by macrophages.	CNR1 CNR2	1.01e-05	2	111	2	19596672
Pubmed	Presence and regulation of cannabinoid receptors in human retinal pigment epithelial cells.	CNR1 CNR2	1.01e-05	2	111	2	19547718
Pubmed	Tamoxifen Isomers and Metabolites Exhibit Distinct Affinity and Activity at Cannabinoid Receptors: Potential Scaffold for Drug Development.	CNR1 CNR2	1.01e-05	2	111	2	27936172
Pubmed	CB1 and CB2 cannabinoid receptor expression during development and in epileptogenic developmental pathologies.	CNR1 CNR2	1.01e-05	2	111	2	20621164
Pubmed	Altered expression of type-1 and type-2 cannabinoid receptors in celiac disease.	CNR1 CNR2	1.01e-05	2	111	2	23620805
Pubmed	Characterization of anandamide-stimulated cannabinoid receptor signaling in human ULTR myometrial smooth muscle cells.	CNR1 CNR2	1.01e-05	2	111	2	19477951
Pubmed	Cannabinoid receptor type 1- and 2-mediated increase in cyclic AMP inhibits T cell receptor-triggered signaling.	CNR1 CNR2	1.01e-05	2	111	2	19858202
Pubmed	Immunolocalization of cannabinoid receptor type 1 and CB2 cannabinoid receptors, and transient receptor potential vanilloid channels in pterygium.	CNR1 CNR2	1.01e-05	2	111	2	28849159
Pubmed	Involvement of CB1 and CB2 receptors in the modulation of cholinergic neurotransmission in mouse gastric preparations.	CNR1 CNR2	1.01e-05	2	111	2	17656103
Pubmed	Silencing of Receptor Tyrosine Kinase ROR1 Inhibits Tumor-Cell Proliferation via PI3K/AKT/mTOR Signaling Pathway in Lung Adenocarcinoma.	ROR1 MTOR	1.01e-05	2	111	2	25978653
Pubmed	Δ⁹-Tetrahydrocannabinol attenuates allogeneic host-versus-graft response and delays skin graft rejection through activation of cannabinoid receptor 1 and induction of myeloid-derived suppressor cells.	CNR1 CNR2	1.01e-05	2	111	2	26034207
Pubmed	Cannabinoid receptors distribution in mouse cortical plasma membrane compartments.	CNR1 CNR2	1.01e-05	2	111	2	34099009
Pubmed	KRAS gene silencing inhibits the activation of PI3K-Akt-mTOR signaling pathway to regulate breast cancer cell epithelial-mesenchymal transition, proliferation and apoptosis.	KRAS MTOR	1.01e-05	2	111	2	32271426
Pubmed	Cannabinoid receptor subtype 2 (CB2R) agonist, GW405833 reduces agonist-induced Ca(2+) oscillations in mouse pancreatic acinar cells.	CNR1 CNR2	1.01e-05	2	111	2	27432473
Pubmed	Expression analysis of cannabinoid receptors 1 and 2 in B cells during pregnancy and their role on cytokine production.	CNR1 CNR2	1.01e-05	2	111	2	27163857
Pubmed	Enhanced humoral immunity in mice lacking CB1 and CB2 receptors (Cnr1-/-/Cnr2-/- mice) is not due to increased splenic noradrenergic neuronal activity.	CNR1 CNR2	1.01e-05	2	111	2	24870806
Pubmed	Mice Missing Cnr1 and Cnr2 Show Implantation Defects.	CNR1 CNR2	1.01e-05	2	111	2	30776303
Pubmed	Expression of the endocannabinoid system in human first trimester placenta and its role in trophoblast proliferation.	CNR1 CNR2	1.01e-05	2	111	2	18599552
Pubmed	CB₂ cannabinoid receptors inhibit synaptic transmission when expressed in cultured autaptic neurons.	CNR1 CNR2	1.01e-05	2	111	2	22579668
Pubmed	Characterization of the effects of cannabinoid receptor deletion on energy metabolism in female C57BL mice.	CNR1 CNR2	1.01e-05	2	111	2	38962676
Pubmed	Genetic association analysis of CNR1 and CNR2 polymorphisms with schizophrenia in a Korean population.	CNR1 CNR2	1.01e-05	2	111	2	25014618
Pubmed	Mice lacking cannabinoid CB1-, CB2-receptors or both receptors show increased susceptibility to trinitrobenzene sulfonic acid (TNBS)-induced colitis.	CNR1 CNR2	1.01e-05	2	111	2	20228420
Pubmed	Hepatic expression of cannabinoid receptors CB1 and CB2 correlate with fibrogenesis in patients with chronic hepatitis B.	CNR1 CNR2	1.01e-05	2	111	2	28315398
Pubmed	Endocannabinoids decrease neuropathic pain-related behavior in mice through the activation of one or both peripheral CB₁ and CB₂ receptors.	CNR1 CNR2	1.01e-05	2	111	2	24148808
Pubmed	Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors.	CNR1 CNR2	1.01e-05	2	111	2	10570211
Pubmed	The inhibitory action of exo- and endocannabinoids on [³H]GABA release are mediated by both CB₁and CB₂receptors in the mouse hippocampus.	CNR1 CNR2	1.01e-05	2	111	2	22133429
Pubmed	The preimplantation mouse embryo is a target for cannabinoid ligand-receptor signaling.	CNR1 CNR2	1.01e-05	2	111	2	7568154
Pubmed	The cannabinoid CB1 receptor regulates bone formation by modulating adrenergic signaling.	CNR1 CNR2	1.01e-05	2	111	2	17704191
Pubmed	CB1 and CB2 receptor mRNA expression in human peripheral blood mononuclear cells (PBMC) from various donor types.	CNR1 CNR2	1.01e-05	2	111	2	11727770
Pubmed	Neuroprotection and Beyond: The Central Role of CB1 and CB2 Receptors in Stroke Recovery.	CNR1 CNR2	1.01e-05	2	111	2	38069049
Pubmed	Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors.	CNR1 CNR2	1.01e-05	2	111	2	12511587
Pubmed	Effects of targeted deletion of cannabinoid receptors CB1 and CB2 on immune competence and sensitivity to immune modulation by Delta9-tetrahydrocannabinol.	CNR1 CNR2	1.01e-05	2	111	2	18791168
Pubmed	Blockade of cannabinoid receptors reduces inflammation, leukocyte accumulation and neovascularization in a model of sponge-induced inflammatory angiogenesis.	CNR1 CNR2	1.01e-05	2	111	2	23722450
Pubmed	Variability in cannabinoid receptor genes is associated with psychiatric comorbidities in anorexia nervosa.	CNR1 CNR2	1.01e-05	2	111	2	33575982
Pubmed	Cnr2 deficiency confers resistance to inflammation-induced preterm birth in mice.	CNR1 CNR2	1.01e-05	2	111	2	25051450
Pubmed	Cannabinoid receptor-mediated regulation of intracellular calcium by delta(9)-tetrahydrocannabinol in resting T cells.	CNR1 CNR2	1.01e-05	2	111	2	14966196
Pubmed	Evaluation of cannabinoid CB1 and CB2 receptors expression in mobile tongue squamous cell carcinoma: associations with clinicopathological parameters and patients' survival.	CNR1 CNR2	1.01e-05	2	111	2	26459312
Pubmed	Yin and yang of cannabinoid CB1 receptor: CB1 deletion in immune cells causes exacerbation while deletion in non-immune cells attenuates obesity.	CNR1 CNR2	1.01e-05	2	111	2	36093055
Pubmed	Cognitive performance and peripheral endocannabinoid system receptor expression in schizophrenia.	CNR1 CNR2	1.01e-05	2	111	2	24853061
Pubmed	Expression and function of cannabinoid receptors in mouse islets.	CNR1 CNR2	1.01e-05	2	111	2	21099327
Pubmed	Expression of the endocannabinoid receptors in human fascial tissue.	CNR1 CNR2	1.01e-05	2	111	2	27349320
Interaction	TRIM28 interactions	KRAS PDS5B ZNF658 HSPH1 PSMC4 TRRAP BIRC6 ZNF284 CSDE1 NAMPT TIAL1 UTP15 MTOR PAFAH1B1 RGPD3 ZNF620 ZNF761 ZNF350 ZNF615 ZNF598 NIPBL MAST3	1.11e-05	1474	109	22	int:TRIM28
Interaction	RELN interactions	KRAS PAFAH1B1 CNR1 CNR2	1.29e-05	27	109	4	int:RELN
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF658 ZBTB8B ZNF215 ZNF275 ZNF284 OVOL2 ZNF800 ZNF620 ZFHX3 ZNF761 ZNF350 ZNF615 ZNF598	8.31e-06	718	76	13	28
GeneFamily	Cannabinoid receptors	CNR1 CNR2	1.74e-05	2	76	2	202
GeneFamily	UNC13 homologs	UNC13D UNC13A	1.04e-04	4	76	2	836
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	ROR1 TEK ROS1	6.31e-04	40	76	3	321
GeneFamily	Heat shock 70kDa proteins	HSPH1 HSPA6	2.28e-03	17	76	2	583
GeneFamily	F-box and leucine rich repeat proteins	FBXL8 SKP2	3.48e-03	21	76	2	558
GeneFamily	Fibronectin type III domain containing	COL20A1 FSD2 TEK ROS1	4.62e-03	160	76	4	555
GeneFamily	WD repeat domain containing	STRN3 DYNC2I1 UTP15 PAFAH1B1 TBL2	4.92e-03	262	76	5	362
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FILIP1 ZBTB8B PCED1B ADGB DNAH12 HYDIN	2.11e-06	150	111	6	53de595376a9fc92491dfd58ff25938b0bf79903
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FILIP1 ZBTB8B PCED1B ADGB DNAH12 HYDIN	2.11e-06	150	111	6	e4b40b3243ed26d0c46bf196ac06e148834e7ed2
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNC2I1 ADGB DNAH12 OSBPL6 VWA3B HYDIN	4.20e-06	169	111	6	fba841664939c771881ba97f14ef1df6635c04ff
ToppCell	Ciliated_cells-B-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	ADGB DNAH12 OSBPL6 FMN2 VWA3B HYDIN	5.48e-06	177	111	6	c38138fb5ad9766c2d240811210c854338cd612e
ToppCell	Ciliated_cells-B-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	DZIP1 ADGB DNAH12 OSBPL6 VWA3B HYDIN	6.42e-06	182	111	6	e44c4810dc7d51a76b86d7623f8e4c4d8b4bf2fc
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL22A1 FREM1 GMNC FAT1 ROS1 HYDIN	6.84e-06	184	111	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL22A1 FREM1 GMNC FAT1 ROS1 HYDIN	6.84e-06	184	111	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL22A1 FREM1 GMNC FAT1 ROS1 HYDIN	6.84e-06	184	111	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	COPD-Endothelial-VE_Capillary_A\|Endothelial / Disease state, Lineage and Cell class	NCALD ACE HECW2 OSBPL6 ZFHX3 CDH12	7.73e-06	188	111	6	1aa0e35b1c28ac847886fece16c3ef7fc6fcdd51
ToppCell	Multiciliated\|World / shred by cell class for nasal brushing	FILIP1 ADGB DNAH12 KLHL7 VWA3B HYDIN	7.97e-06	189	111	6	34b110aef839376228c5a403a6b5047a945f472b
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FILIP1 DOCK9 TEK ACE HECW2 RPGR	8.21e-06	190	111	6	06bfb62b94b0faf467ef93d5bc5d08924c770098
ToppCell	BL-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FILIP1 ADGB DNAH12 OSBPL6 VWA3B HYDIN	9.52e-06	195	111	6	07a6bcef6af93ed87df455dee624037cb75e011a
ToppCell	PSB-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FILIP1 ADGB DNAH12 OSBPL6 VWA3B HYDIN	1.01e-05	197	111	6	6865f4831eb23794fb88a8649d48d497bbae3f44
ToppCell	NS-moderate-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FILIP1 DYNC2I1 ADGB DNAH12 VWA3B HYDIN	1.01e-05	197	111	6	71fea4aa6ce96c7693fa94792d08770622873850
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNC2I1 ADGB DNAH12 OSBPL6 VWA3B HYDIN	1.01e-05	197	111	6	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	Ciliated_cells-A-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	RGPD1 ADGB GMNC DNAH12 HYDIN	3.27e-05	146	111	5	20f080318e9cbfd9b8b90a5e9f704d6d85b969ee
ToppCell	(6)_Endothelial_cells-(6)_Endothelial-C_(Capillary_Aerocyte_)\|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	NCALD ACE DPEP2 HECW2 SERPINB1	4.62e-05	157	111	5	84f629b7f589ca8a1abc220fa740c4a6fdc1b579
ToppCell	Control-Endothelial_cells-Inflamed_endothelial_cells\|Control / group, cell type (main and fine annotations)	NCALD DOCK9 TEK ACE HECW2	5.05e-05	160	111	5	958256e3d3836160763b82bb48f794087918d935
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NCALD DOCK9 TEK PDE8B HECW2	6.55e-05	169	111	5	987ff79ad563825dd9877ea8ccb536758f8c6700
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRAS INF2 SERPINB1 TM4SF20 AMIGO2	6.55e-05	169	111	5	8dba7546adc6b1345933eec81fc77fc9611fae60
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_ETV4\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FILIP1 ZNF658B FREM1 ZFHX3 ROS1	6.55e-05	169	111	5	716e9d4c5fb99c56b76afaa5ed90bfa859fde802
ToppCell	facs-Lung-Endomucin-24m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRAS INF2 SERPINB1 TM4SF20 AMIGO2	6.55e-05	169	111	5	d2862a7ddee6d7a65d84ef9d0800ba6f4690973f
ToppCell	facs-Lung-nan-3m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRAS ZNF280C TEK HECW2 AMIGO2	6.73e-05	170	111	5	8e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCell	facs-Lung-nan-3m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRAS ZNF280C TEK HECW2 AMIGO2	6.73e-05	170	111	5	67d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FBXL8 ZNF275 PDE8B GLRA1 CNR2	7.31e-05	173	111	5	e4d9a9a781acc531bc81c3fcee24d637e805c8e1
ToppCell	Control-CD4+_T_activated\|Control / Disease group and Cell class	HSPH1 HECW2 FAM157C DDTL HSPA6	7.52e-05	174	111	5	2b683e81b315ad22555314433aed5681feb48da8
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Epcam____podocyte-3\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS13 ZBTB8B ADGB FMN2 ROS1	7.52e-05	174	111	5	76310c0af1d7df6a4de3816838b2ac2892f68746
ToppCell	Ciliated_cells-A-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	ADGB DNAH12 OSBPL6 VWA3B HYDIN	7.93e-05	176	111	5	1c364155f46b9a7c995bdc2cc2333c437cd90f5b
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-RGCs_early_2\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	FREM1 ADGB DNAH12 DPEP2 HYDIN	7.93e-05	176	111	5	8e0ac3ad5e47614b4befabd674a40e3eaae553f3
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NCALD TEK PCED1B HECW2 FDXACB1	7.93e-05	176	111	5	dc5a22f9d1347f157bdd93e6e5769b983deccf1a
ToppCell	Ciliated_cells-B-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	DNAH12 OSBPL6 FMN2 VWA3B HYDIN	8.82e-05	180	111	5	bdea5ec6b60fc8c7cce4d71db5da74ac8675e211
ToppCell	Control-Epithelial_cells-Airway_ciliated\|Control / group, cell type (main and fine annotations)	ADGB DNAH12 FMN2 VWA3B HYDIN	9.29e-05	182	111	5	fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADGB DNAH12 FMN2 VWA3B HYDIN	9.78e-05	184	111	5	5daff849625f2f41d56615569c0ed59cd733b34c
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FILIP1 ADGB DNAH12 VWA3B HYDIN	1.00e-04	185	111	5	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	Ciliated_cells-B-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	ADGB DNAH12 OSBPL6 VWA3B HYDIN	1.00e-04	185	111	5	f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCell	Control-Epithelial_alveolar\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FILIP1 ROR1 UNC13D DDT OVOL2	1.00e-04	185	111	5	3937e026add96a396122139daf8011cfbc60e75c
ToppCell	Adult-Epithelial-ciliated_cell-D175\|Adult / Lineage, Cell type, age group and donor	ADGB DNAH12 FMN2 VWA3B HYDIN	1.00e-04	185	111	5	30f4980dee6cd5959655f8d74049f3bfb5312611
ToppCell	NS-critical-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FILIP1 ADGB DNAH12 VWA3B HYDIN	1.03e-04	186	111	5	76033438426d8f9c72cd6691a7baf92104c9f03d
ToppCell	NS-moderate-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FILIP1 ADGB DNAH12 VWA3B HYDIN	1.03e-04	186	111	5	85787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DOCK9 XPO4 CHD9 TEK ACE	1.05e-04	187	111	5	3699d5e71d779da922920aa3160895db187bf81b
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DOCK9 XPO4 CHD9 TEK ACE	1.05e-04	187	111	5	033ba52c0c2f9978784947098fa697368ae44834
ToppCell	Epithelial-ciliated_cell\|World / Lineage, Cell type, age group and donor	ADGB DNAH12 FMN2 VWA3B HYDIN	1.08e-04	188	111	5	61a459f3fe57e5728efc72637ff2edc2d343492b
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADGB DNAH12 FMN2 VWA3B HYDIN	1.08e-04	188	111	5	2b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCell	facs-MAT-Fat-18m\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KMT2B PSMC4 BIRC6 DDT LYPD8	1.08e-04	188	111	5	7f0cda7aab442aa9511d4c35569ec2389e014a71
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADGB DNAH12 FMN2 VWA3B HYDIN	1.11e-04	189	111	5	68a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCell	Epithelial-D_(Ciliated)\|World / shred on cell class and cell subclass (v4)	DYNC2I1 ADGB DNAH12 OSBPL6 HYDIN	1.11e-04	189	111	5	0bf560b595c7a8450a46bc821b742b67965bd9f9
ToppCell	Nasal_Brush-Epithelial-Ciliated_2\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	FILIP1 ADGB DNAH12 VWA3B HYDIN	1.14e-04	190	111	5	9ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCell	343B-Epithelial_cells-Epithelial-F_(Ciliated)\|343B / Donor, Lineage, Cell class and subclass (all cells)	ADGB DNAH12 OSBPL6 VWA3B HYDIN	1.14e-04	190	111	5	169e600e95878000acf5d11f813f9028c7249646
ToppCell	343B-Epithelial_cells-Epithelial-F_(Ciliated)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	ADGB DNAH12 OSBPL6 VWA3B HYDIN	1.14e-04	190	111	5	0cc36117c793d83cf4a1f66f47758a07d6712bd3
ToppCell	Nasal_Brush-Epithelial-Ciliated_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	FILIP1 ADGB DNAH12 VWA3B HYDIN	1.14e-04	190	111	5	833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NCALD DOCK9 TEK ACE HECW2	1.14e-04	190	111	5	474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCell	Ciliated_cells-A\|World / lung cells shred on cell class, cell subclass, sample id	ADGB DNAH12 OSBPL6 VWA3B HYDIN	1.14e-04	190	111	5	cd87731aaa7d252424f79cfce9f7931457f17bdf
ToppCell	BAL-Mild-Epithelial-Epithelial-Ciliated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ADGB DNAH12 OSBPL6 VWA3B HYDIN	1.16e-04	191	111	5	2a8e6d560907e71e9f6e190ca0667da804e25641
ToppCell	BAL-Mild-Epithelial-Epithelial-Ciliated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ADGB DNAH12 OSBPL6 VWA3B HYDIN	1.16e-04	191	111	5	46c9d4d10c66c0fae1fa351924091b69ea2f38d4
ToppCell	PND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DYNC2I1 ADGB DNAH12 OSBPL6 HYDIN	1.16e-04	191	111	5	bda8faf92495c8b362850c0aff4fc6fbdd9c563b
ToppCell	PND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DYNC2I1 ADGB DNAH12 OSBPL6 HYDIN	1.16e-04	191	111	5	6880fb348bb0915db9a5da4f3566ca9ff93ed258
ToppCell	Mild_COVID-19-Epithelial-Ciliated\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	ADGB DNAH12 OSBPL6 VWA3B HYDIN	1.16e-04	191	111	5	995e76bbf07674d95b8ef09e078cf6410af27a09
ToppCell	BAL-Mild-Epithelial-Epithelial-Ciliated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ADGB DNAH12 OSBPL6 VWA3B HYDIN	1.16e-04	191	111	5	a37f20172b85566b9039254a89680e37fd503fd5
ToppCell	BAL-Mild-Epithelial-Epithelial-Ciliated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	ADGB DNAH12 OSBPL6 VWA3B HYDIN	1.16e-04	191	111	5	2d36e08c5629cf73b6dd02cd173cafb52e8a3a7d
ToppCell	PND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DYNC2I1 ADGB DNAH12 OSBPL6 HYDIN	1.19e-04	192	111	5	b5cdc2dae3154b1e4ade88f841f38584402ffe33
ToppCell	facs-Lung-nan-3m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCALD DOCK9 TEK ACE HECW2	1.19e-04	192	111	5	4bab9754cfd8b9c2d7cc1490e8a29f58c3c26f6c
ToppCell	droplet-Lung-30m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MRAS DOCK9 TEK HECW2 AMIGO2	1.19e-04	192	111	5	452d54f0aca8657722d7ac61e8422921d08c06b3
ToppCell	droplet-Lung-30m-Endothelial-venous_endothelial-vein_endothelial_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MRAS DOCK9 TEK HECW2 AMIGO2	1.19e-04	192	111	5	7ddaca206599603d4d0b2afb73ed2850225d277d
ToppCell	droplet-Lung-30m-Endothelial-venous_endothelial\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MRAS DOCK9 TEK HECW2 AMIGO2	1.19e-04	192	111	5	bf0b996aeedc34a79c71df3379ec9c1aabe06a8c
ToppCell	PND03-Epithelial-Epithelial_Airway\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DYNC2I1 ADGB DNAH12 OSBPL6 HYDIN	1.19e-04	192	111	5	2d8d5a38e205339eda9c8aca1ca9ba3dcbe5ae56
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FILIP1 DYNC2I1 ADGB VWA3B HYDIN	1.22e-04	193	111	5	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	IPF-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	DYNC2I1 ADGB DNAH12 VWA3B HYDIN	1.22e-04	193	111	5	ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH12 OSBPL6 VWA3B ROS1 HYDIN	1.22e-04	193	111	5	bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ROR1 FREM1 FAT1 ZFHX3 CDH12	1.22e-04	193	111	5	e2b455387d1de7812305200a2041a0f4759a6f54
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ADGB DNAH12 OSBPL6 VWA3B HYDIN	1.25e-04	194	111	5	756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCell	ASK440-Epithelial-Ciliated\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	POLR2I ADGB DNAH12 VWA3B HYDIN	1.25e-04	194	111	5	c84a7fa94fb06e08aae04db56c8c313b0afde1d7
ToppCell	Bronchial_Brush-Epithelial-Ciliated_1\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	DYNC2I1 ADGB DNAH12 VWA3B HYDIN	1.25e-04	194	111	5	b4ce60c06568123008b1081d644733cb91c28f51
ToppCell	NS-critical-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FILIP1 ADGB DNAH12 VWA3B HYDIN	1.25e-04	194	111	5	1ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCell	IPF-Endothelial-VE_Capillary_A\|Endothelial / Disease state, Lineage and Cell class	NCALD ACE HECW2 OSBPL6 SERPINB1	1.25e-04	194	111	5	777ce41c3f22c591e2d81120f189b834e53ffb4b
ToppCell	Bronchial_Brush-Epithelial-Ciliated_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	DYNC2I1 ADGB DNAH12 VWA3B HYDIN	1.25e-04	194	111	5	7a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NCALD DOCK9 TEK HECW2 RPGR	1.25e-04	194	111	5	40842a7160f337bfc191ee15fbda3e3d38a04c57
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNC2I1 ADGB DNAH12 VWA3B HYDIN	1.28e-04	195	111	5	649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HSPH1 NAMPT HSPA6 LRRFIP1 ADSS1	1.28e-04	195	111	5	042b4f44f90eb23caadeced43699b51e5195ab04
ToppCell	NS-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FILIP1 ADGB DNAH12 VWA3B HYDIN	1.28e-04	195	111	5	34e37cff4849696ca4ba5dd8fd2cf98fed8bc912
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNC2I1 ADGB DNAH12 VWA3B HYDIN	1.28e-04	195	111	5	129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNC2I1 ADGB DNAH12 VWA3B HYDIN	1.28e-04	195	111	5	3e70ee987d66d450062d5df3d7c733ccc7344470
ToppCell	moderate-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	FILIP1 ADGB DNAH12 VWA3B HYDIN	1.28e-04	195	111	5	3486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCell	moderate-Epithelial-Ciliated\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	FILIP1 ADGB DNAH12 VWA3B HYDIN	1.28e-04	195	111	5	e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCell	background-Endothelial_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	FILIP1 DOCK9 TEK PCED1B HECW2	1.31e-04	196	111	5	e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCell	critical-Epithelial-Ciliated\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	FILIP1 ADGB DNAH12 VWA3B HYDIN	1.31e-04	196	111	5	27b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCell	NS-control-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FILIP1 ADGB DNAH12 VWA3B HYDIN	1.31e-04	196	111	5	d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HSPH1 NAMPT HSPA6 LRRFIP1 ADSS1	1.35e-04	197	111	5	6c42ce26574adcc6dfc5dd8109c9943fe5cf12d5
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNC2I1 ADGB DNAH12 VWA3B HYDIN	1.35e-04	197	111	5	91637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNC2I1 ADGB DNAH12 VWA3B HYDIN	1.35e-04	197	111	5	22c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNC2I1 ADGB DNAH12 VWA3B HYDIN	1.35e-04	197	111	5	3bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma-tip_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	FILIP1 DOCK9 TEK ACE HECW2	1.35e-04	197	111	5	b212ff28ca2d1fea4140f186ab90941bdca21249
ToppCell	control-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	FILIP1 ADGB DNAH12 VWA3B HYDIN	1.35e-04	197	111	5	e453d085182364ca347cbcc9dc995c62c3353016
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNC2I1 ADGB DNAH12 VWA3B HYDIN	1.35e-04	197	111	5	87db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCell	control-Epithelial-Ciliated\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	FILIP1 ADGB DNAH12 VWA3B HYDIN	1.35e-04	197	111	5	d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCell	wk_20-22-Epithelial-Proximal_epithelial\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ADGB DNAH12 OSBPL6 VWA3B HYDIN	1.38e-04	198	111	5	16c54b884500066ade05a406915f9569ca8abdfc
ToppCell	critical-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	FILIP1 ADGB DNAH12 VWA3B HYDIN	1.38e-04	198	111	5	ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NCALD OSBPL6 FMN2 UNC13A CDH12	1.38e-04	198	111	5	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NCALD DOCK9 TEK PCED1B HECW2	1.38e-04	198	111	5	fa84bf8533d1b91d2c2bcf06b710670605072b89
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADGB DNAH12 OSBPL6 VWA3B HYDIN	1.41e-04	199	111	5	92fdf6e2f0786ab2ab78126e9131a93794168139
ToppCell	proximal-Epithelial-Ciliated\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ADGB DNAH12 OSBPL6 VWA3B HYDIN	1.41e-04	199	111	5	9700f06e51ddca85e482b4f9bd4a79bfcd3cfb76
Drug	arachidoylethanolamide	CNR1 CNR2	2.31e-05	2	110	2	CID003787294
Drug	Cerebrodiene	CNR1 CNR2	2.31e-05	2	110	2	CID006439505
Drug	Nabilone	CNR1 CNR2	2.31e-05	2	110	2	DB00486
Drug	Dronabinol	CNR1 CNR2	2.31e-05	2	110	2	DB00470
Drug	3-pentylphenol	CNR1 CNR2	2.31e-05	2	110	2	CID000088345
Drug	CP-47,497	CNR1 CNR2	2.31e-05	2	110	2	CID000125835
Drug	AC1L399Q	CNR1 CNR2	2.31e-05	2	110	2	CID000111274
Drug	AC1LD0O8	CNR1 CNR2	2.31e-05	2	110	2	CID000640435
Drug	JWH-073	CNR1 CNR2	2.31e-05	2	110	2	ctd:C568258
Drug	1,3-dihydroxypropan-2-yl 11-(3-hydroxy-5-(2-methyloctan-2-yl)phenoxy)undecanoate	CNR1 CNR2	2.31e-05	2	110	2	ctd:C570532
Drug	1,3,5-triphenylhydantoin	CNR1 CNR2	2.31e-05	2	110	2	CID011609579
Drug	3-(2-cyano-3-(trifluoromethyl)phenoxy)phenyl-4,4,4-trifluoro-1-butanesulfonate	CNR1 CNR2	2.31e-05	2	110	2	ctd:C498148
Drug	1-pentyl-3-(1-naphthoyl)indole	CNR1 CNR2	2.31e-05	2	110	2	ctd:C552597
Drug	L759633	CNR1 CNR2	2.31e-05	2	110	2	CID005311215
Drug	L759656	CNR1 CNR2	2.31e-05	2	110	2	CID005311216
Drug	11-Hydroxycannabinol	CNR1 CNR2	2.31e-05	2	110	2	CID003082311
Drug	1-pentyne	CNR1 CNR2	2.31e-05	2	110	2	CID000012309
Drug	tetrahydrocannabivarin	CNR1 CNR2	2.31e-05	2	110	2	CID000034180
Drug	HU-243	CNR1 CNR2	2.31e-05	2	110	2	CID003081854
Drug	Clozapine [5786-21-0]; Up 200; 12.2uM; PC3; HT_HG-U133A	MRAS DOCK9 ADGB SYCP1 TBL2 UNC13A LRRFIP1	4.30e-05	193	110	7	4670_UP
Drug	Cp55	CNR1 CNR2	6.92e-05	3	110	2	CID010513376
Drug	AC1MI0NY	CNR1 CNR2	6.92e-05	3	110	2	CID003036153
Drug	2-octyn-1-ol	CNR1 CNR2	6.92e-05	3	110	2	CID000140750
Drug	AM 281	CNR1 CNR2	6.92e-05	3	110	2	CID004302962
Drug	CP-272871	CNR1 CNR2	6.92e-05	3	110	2	CID000188204
Drug	1,5-diphenyl-1H-pyrazole	CNR1 CNR2	6.92e-05	3	110	2	CID000613283
Drug	THC-DMH	CNR1 CNR2	6.92e-05	3	110	2	CID003032800
Drug	Tag Peptide	HSPH1 BIRC6 NAMPT	7.10e-05	17	110	3	CID005486959
Drug	Pyrazoles	ACE CNR1 CNR2	1.18e-04	20	110	3	ctd:D011720
Drug	Bradykinin[1-8]	ACE CNR1 CNR2	1.37e-04	21	110	3	CID000105044
Drug	dipyridamole	ACE F2RL1 BIRC6 FAT1 PDE8B SERPINB1	1.38e-04	162	110	6	CID000003108
Drug	AC1L1BF2	CNR1 CNR2	1.38e-04	4	110	2	CID000001411
Drug	CP-55,244	CNR1 CNR2	1.38e-04	4	110	2	CID000133254
Drug	DBD-COCl	CNR1 CNR2	1.38e-04	4	110	2	CID000133003
Drug	AC1L1CNE	CNR1 CNR2	1.38e-04	4	110	2	CID000001977
Disease	Ovarian Mucinous Adenocarcinoma	ROR1 TRRAP MTOR	1.83e-04	31	105	3	C1335167
Disease	Hemimegalencephaly	KRAS MTOR	1.86e-04	6	105	2	C0431391
Disease	Large cell carcinoma of lung	TRRAP MTOR ROS1	2.01e-04	32	105	3	C0345958
Disease	Writer's Cramp	KMT2B GLRA1	2.60e-04	7	105	2	C4316810
Disease	Dystonia Disorders	KMT2B GLRA1	2.60e-04	7	105	2	C0393593
Disease	Idiopathic familial dystonia	KMT2B GLRA1	2.60e-04	7	105	2	C0393598
Disease	Adult-Onset Idiopathic Focal Dystonias	KMT2B GLRA1	2.60e-04	7	105	2	C0752198
Disease	Adult-Onset Dystonias	KMT2B GLRA1	2.60e-04	7	105	2	C0752197
Disease	Adult-Onset Idiopathic Torsion Dystonias	KMT2B GLRA1	2.60e-04	7	105	2	C0752199
Disease	Autosomal Dominant Familial Dystonia	KMT2B GLRA1	2.60e-04	7	105	2	C0752200
Disease	Childhood Onset Dystonias	KMT2B GLRA1	2.60e-04	7	105	2	C0752202
Disease	Autosomal Recessive Familial Dystonia	KMT2B GLRA1	2.60e-04	7	105	2	C0752201
Disease	Dystonia, Primary	KMT2B GLRA1	2.60e-04	7	105	2	C0752203
Disease	Dystonias, Sporadic	KMT2B GLRA1	2.60e-04	7	105	2	C0752206
Disease	Dystonia, Secondary	KMT2B GLRA1	2.60e-04	7	105	2	C0752205
Disease	Pseudodystonia	KMT2B GLRA1	2.60e-04	7	105	2	C0752208
Disease	Familial Dystonia	KMT2B GLRA1	2.60e-04	7	105	2	C0752207
Disease	Focal Dystonia	KMT2B GLRA1	2.60e-04	7	105	2	C0743332
Disease	Adenocarcinoma of large intestine	KRAS ROR1 TRRAP ROS1	3.91e-04	96	105	4	C1319315
Disease	mitral valve prolapse (is_implicated_in)	DZIP1 ACE	4.44e-04	9	105	2	DOID:988 (is_implicated_in)
Disease	Pancreatic Neoplasm	KRAS SYCP1 CNR1 CNR2	4.57e-04	100	105	4	C0030297
Disease	Malignant neoplasm of pancreas	KRAS SYCP1 CNR1 CNR2	4.92e-04	102	105	4	C0346647
Disease	schizophrenia (is_marker_for)	ACE OPA1 PAFAH1B1	5.22e-04	44	105	3	DOID:5419 (is_marker_for)
Disease	middle cerebral artery infarction (implicated_via_orthology)	ACE NAMPT MTOR	5.57e-04	45	105	3	DOID:3525 (implicated_via_orthology)
Disease	glomerulosclerosis (implicated_via_orthology)	ACE INF2	6.76e-04	11	105	2	DOID:0050851 (implicated_via_orthology)
Disease	Carcinoma, Granular Cell	KRAS ACE MTOR SYCP1	7.98e-04	116	105	4	C0205644
Disease	Adenocarcinoma, Tubular	KRAS ACE MTOR SYCP1	7.98e-04	116	105	4	C0205645
Disease	Adenocarcinoma, Oxyphilic	KRAS ACE MTOR SYCP1	7.98e-04	116	105	4	C0205642
Disease	Carcinoma, Cribriform	KRAS ACE MTOR SYCP1	7.98e-04	116	105	4	C0205643
Disease	Adenocarcinoma, Basal Cell	KRAS ACE MTOR SYCP1	7.98e-04	116	105	4	C0205641
Disease	Adenocarcinoma	KRAS ACE MTOR SYCP1	7.98e-04	116	105	4	C0001418
Disease	Carcinogenesis	KRAS PAFAH1B1	9.54e-04	13	105	2	C0596263
Disease	benign prostatic hyperplasia	DPEP2 UNC13A	1.11e-03	14	105	2	EFO_0000284
Disease	Malignant Neoplasms	KRAS SKP2 BIRC6 MTOR	1.15e-03	128	105	4	C0006826
Disease	autosomal recessive polycystic kidney disease (implicated_via_orthology)	ACE MTOR	1.46e-03	16	105	2	DOID:0110861 (implicated_via_orthology)
Disease	renal fibrosis (implicated_via_orthology)	KRAS ACE	1.65e-03	17	105	2	DOID:0050855 (implicated_via_orthology)
Disease	Hemangiosarcoma	KRAS TEK	1.85e-03	18	105	2	C0018923
Disease	Benign Neoplasm	KRAS SKP2 BIRC6	1.86e-03	68	105	3	C0086692
Disease	Neoplasms	KRAS SKP2 BIRC6	1.86e-03	68	105	3	C0027651
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	ROR1 TEK MTOR FMN2	1.96e-03	148	105	4	C0279702
Disease	Noonan-Like Syndrome With Loose Anagen Hair	KRAS MRAS	2.06e-03	19	105	2	C3501846
Disease	Noonan syndrome-like disorder with loose anagen hair	KRAS MRAS	2.06e-03	19	105	2	C1843181
Disease	Cardio-facio-cutaneous syndrome	KRAS MRAS	2.06e-03	19	105	2	C1275081
Disease	Costello syndrome (disorder)	KRAS MRAS	2.06e-03	19	105	2	C0587248
Disease	end stage renal disease (implicated_via_orthology)	ACE MTOR	2.29e-03	20	105	2	DOID:783 (implicated_via_orthology)
Disease	Unipolar Depression	ACE MTOR MMP8 CNR1 CNR2	2.37e-03	259	105	5	C0041696
Disease	haptoglobin measurement	ZFHX3 HYDIN	2.52e-03	21	105	2	EFO_0004640
Disease	Self-injurious behavior	PDS5B NIPBL CNR1	2.74e-03	78	105	3	HP_0100716
Disease	nucleus accumbens volume	BIRC6 GMNC	2.77e-03	22	105	2	EFO_0006931
Disease	LEOPARD Syndrome	KRAS MRAS	2.77e-03	22	105	2	C0175704
Disease	Kidney Failure	ACE INF2	2.77e-03	22	105	2	C0035078
Disease	Renal glomerular disease	KRAS INF2	3.02e-03	23	105	2	C0268731
Disease	Epilepsy, Benign Psychomotor, Childhood	TEK CNR1	3.02e-03	23	105	2	C0393672
Disease	Ovarian Serous Adenocarcinoma	TEK TRRAP	3.02e-03	23	105	2	C1335177
Disease	Epilepsy, Lateral Temporal	TEK CNR1	3.02e-03	23	105	2	C0393682
Disease	Glomerulopathy Assessment	KRAS INF2	3.02e-03	23	105	2	C4521256
Disease	sciatic neuropathy (implicated_via_orthology)	MTOR CNR2	3.02e-03	23	105	2	DOID:11446 (implicated_via_orthology)
Disease	Uncinate Epilepsy	TEK CNR1	3.02e-03	23	105	2	C0014558
Disease	Epilepsy, Temporal Lobe	TEK CNR1	3.02e-03	23	105	2	C0014556
Disease	cardioembolic stroke	FILIP1 TEK VRTN ZFHX3	3.24e-03	170	105	4	EFO_1001976
Disease	Coronary heart disease	MRAS ACE	3.29e-03	24	105	2	C0010068
Disease	Neoplasm of the genitourinary tract	KRAS ZFHX3	3.29e-03	24	105	2	cv:C0042065
Disease	nephrotic syndrome (implicated_via_orthology)	ACE FAT1	3.29e-03	24	105	2	DOID:1184 (implicated_via_orthology)
Disease	congenital diaphragmatic hernia (biomarker_via_orthology)	ACE FREM1	3.29e-03	24	105	2	DOID:3827 (biomarker_via_orthology)
Disease	Noonan Syndrome	KRAS MRAS	3.29e-03	24	105	2	C0028326

Protein segments in the cluster

Peptide	Gene	Start	Entry
NFHFECHNSSDRIKV	UNC13A	726	Q9UPW8
QSTFHAQACEELFKH	BIRC6	2051	Q9NR09
VTRNETHFDAGAKFH	ACE	506	P12821
DKELTAQHFRVFHLS	ADGB	831	Q8N7X0
AAFGDQQATESHHRK	AFTPH	586	Q6ULP2
GFIETANHDKEIFFH	CSDE1	531	O75534
TVSRSHAHEAFNTAF	AMIGO2	386	Q86SJ2
HAHEAFNTAFTTLAA	AMIGO2	391	Q86SJ2
IGHIFSTDKNFHNDA	CCDC144CP	361	Q8IYA2
AAFTTTLQHHKDEVA	ARL2BP	91	Q9Y2Y0
DVHADRNTFHRFDKF	AMPD2	476	Q01433
VNHSLSVFHTKDFQD	ANO9	651	A1A5B4
SHSAHFFEFLTKELA	DDTL	76	A6NHG4
FVNFHVFHGVDSKAV	CNR2	91	P34972
ESKVDAVFQQEHFFH	MMP8	421	P22894
VFAINNTKSFEDIHH	KRAS	81	P01116
DKASFEHVDRFHQLI	MRAS	96	O14807
HCIHAIFSSKETQFA	PDS5B	731	Q9NTI5
LNAHEHFVTSLDFHK	PAFAH1B1	376	P43034
DHQGKAFFVDHNSRT	HECW2	996	Q9P2P5
HVTYHIVNDFAKDRF	FAT1	2526	Q14517
VHEVFSRNHAAPFSK	HSPH1	416	Q92598
HKEGFHFDDERHQSN	DYNC2I1	261	Q8WVS4
NSTHAADVLHATAFF	PDE8B	616	O95263
ANFHSATEARKHNFD	PCED1B	196	Q96HM7
SHSAHFFEFLTKELA	DDT	76	P30046
VRYHHDDSDSTKDFV	FREM1	481	Q5H8C1
QFHIFAEDQLHHSFK	GXYLT1	146	Q4G148
VLEAFFHTQSSVRHF	NIPBL	2286	Q6KC79
VIKDHFKESFHSIFS	DNAH12	2151	Q6ZR08
TEQHSHSFVKKAFRF	FAM157C	111	P0CG43
SSFSHVDEIKEFLHF	LY75	686	O60449
AVSQRFEDGHYKSVH	KMT2B	1451	Q9UMN6
LKATADDFIHQHFTE	KLHL7	161	Q8IXQ5
FNDTFDLKRHVRTHT	OVOL2	156	Q9BRP0
EDKGFRFFSEQVSHH	OSBPL6	661	Q9BZF3
HQEVFASLFHKVSCS	INF2	271	Q27J81
HHVALFKDSSREFDL	OPA1	336	O60313
FVSHDFRDHAKNALL	F2RL1	346	P55085
FKHFHSVDIQASEIV	RGPD3	631	A6NKT7
HQNKSFVAHHDFALF	CHD9	151	Q3L8U1
FHADKRVLHETGFST	HYDIN	1626	Q4G0P3
QRHFFSKHDNRTSFD	C3orf84	51	H3BNL1
KISADFHVDLNHFSV	DOCK9	411	Q9BZ29
VSQASHVSKFDSFHE	COL20A1	1201	Q9P218
FCVVSHSVLDAFRAH	FBXL8	336	Q96CD0
ATEKQIFEDHVFCHS	CALCOCO2	431	Q13137
DFHVFHRKDSRNVFL	CNR1	176	P21554
HVFHVSDFNAIDKIR	COL22A1	196	Q8NFW1
AAHAVYEQKHDASAL	MASP2	481	O00187
TAFTVHVSAEEHFHF	LYPD8	81	Q6UX82
HFLSKHFRSSENVLD	MAST3	126	O60307
NVSTVADHFDHIKAV	DPEP2	326	Q9H4A9
FKVEASNLHLDHRFH	CDH12	346	P55289
RFIIVSAFDHFASVH	HSPB11	116	Q9Y547
KTFHFNTVEEVHSRF	SERPINB1	56	P30740
DRVAAKNSLEAHVFH	HSPA6	536	P17066
IGHIFSTDKNFHNDA	CCDC144A	411	A2RUR9
EFSSHFKNVHGDIHA	FBXO30	531	Q8TB52
DKSFHVEGALNHIFT	FDXACB1	181	Q9BRP7
EFQTSHEHSVSSAFK	FMN2	836	Q9NZ56
ASKFAEHVFRTFDAN	NCALD	61	P61601
HDLNHTVFQVKDSTF	C14orf178	71	Q8N769
TDEAFKDQIHHRVSS	FTCD	506	O95954
EREKHAHSILQFQFA	LRRFIP1	221	Q32MZ4
FKHFHSVDIQASEIV	RGPD1	621	P0DJD0
SFHAFQTAEGIRKAH	MIOX	96	Q9UGB7
SFEFEGHSLTQFVRH	MTOR	591	P42345
ERNTFHVISFFTSEH	RPGR	126	Q92834
RQFEGHTKAVHTVDF	UTP15	116	Q8TED0
FKHFHSVDIQASEIV	RGPD4	631	Q7Z3J3
TITAHEDRHIKFFDN	STRN3	696	Q13033
SDRAHLVFDFHQAVD	ADSS1	131	Q8N142
AKAVAHHTTAAFIRV	PSMC4	216	P43686
VDFEHKASRFSQEHE	FILIP1	301	Q7Z7B0
KTHSFHQGQAFVRRD	GMNC	306	A6NCL1
HHDTFFTKALEHRVA	FASTKD3	346	Q14CZ7
LFFANEKGAHFHEIT	GLRA1	126	P23415
EHSKLSFFNVDLSQH	FSD2	696	A1L4K1
HKEAVFFQSHSARAE	POLR2I	91	P36954
DHEKDAFEHIVTQFS	NAMPT	256	P43490
LHQDVHHFNSFDKVR	SGSH	91	P51688
ELEAAHHASAVRFSK	DZIP1	256	Q86YF9
RASSFHFDSEENKHR	TM4SF20	171	Q53R12
HFDSEENKHRLIHFS	TM4SF20	176	Q53R12
IINSFAEHNFVAKAH	CLEC17A	291	Q6ZS10
LSSHFFVHKDLAARN	ROR1	606	Q01973
CFDFTEKHVQVAVAH	SKP2	266	Q13309
AEFNRDGKSLFHANH	ZNF615	156	Q8N8J6
FRSNFEIHRKIHTED	ZNF761	421	Q86XN6
DDKHFHKGFFTQHAV	XPO4	416	Q9C0E2
AHRTTEVAHRDFANS	TMPRSS13	271	Q9BYE2
SNKARAAHSFVVTEF	SYCP1	366	Q15431
FTDTSARHHEAYEVK	ZNF620	151	Q6ZNG0
FSAHSKFLASEQHSL	ROS1	986	P08922
KDFNHTDHFSVAIFT	TEK	396	Q02763
LDFTAHQRIHTEDKF	ZNF658	366	Q5TYW1
HDAFENIVHCSKSQF	ZNF350	106	Q9GZX5
QFTHAFRTEIDLKAH	ZNF598	251	Q86UK7
THDSEASRQKFRHFQ	ZNF215	41	Q9UL58
FATKANVRRHFDEVH	ZNF800	296	Q2TB10
SDVEAHFRAAHENTK	ZNF280C	426	Q8ND82
AKTHSRFHAFAERTE	VWA3B	286	Q502W6
AARFSAKHFLQDSFH	VRTN	311	Q9H8Y1
VAEFNEHRKSHVAAE	ZNF275	141	Q9NSD4
KDTSNHFHVFVGDLS	TIAL1	91	Q01085
RAEEIVAAQEKSFHH	TRRAP	1226	Q9Y4A5
FLHATQKDLSDFHQS	UNC13D	336	Q70J99
RAFELKGHSAAVHSF	TBL2	271	Q9Y4P3
LSHRDTFHFQREEKF	ZNF284	51	Q2VY69
FTHFEKEKQHDIRSF	ZRANB3	511	Q5FWF4
FKTSAALQTHFNEVH	ZFHX3	1371	Q15911
KLDFTAHQRIHTDFT	ZNF658B	121	Q4V348
RNSAAPSKDDADHHF	ZBTB8B	286	Q8NAP8
LKHFNVRVTHADIFS	EXD3	711	Q8N9H8
FKHSRSAAVTSEFHL	NECTIN4	196	Q96NY8