Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-8 ERVK-18 ERVK-19 ERVK-25 ERVK-24

7.44e-12371539GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-8 ERVK-18 ERVK-19 ERVK-25 ERVK-24

9.68e-12381539GO:0070001
GeneOntologyMolecularFunctionnuclear import signal receptor activity

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

3.49e-07201535GO:0061608
GeneOntologyMolecularFunctionnuclear localization sequence binding

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

1.74e-06271535GO:0008139
GeneOntologyMolecularFunctionnucleocytoplasmic carrier activity

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

4.22e-06321535GO:0140142
GeneOntologyMolecularFunctionsignal sequence binding

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

4.37e-05511535GO:0005048
GeneOntologyMolecularFunctionRNA-DNA hybrid ribonuclease activity

ERVK-6 ERVK-7 ERVK-8

6.96e-05111533GO:0004523
GeneOntologyMolecularFunctionnuclear receptor coactivator activity

NCOA3 ETS1 ZMIZ1 TMF1 MED12

1.04e-04611535GO:0030374
GeneOntologyMolecularFunctionRNA-directed DNA polymerase activity

ERVK-6 ERVK-7 ERVK-8

1.51e-04141533GO:0003964
GeneOntologyMolecularFunctionRNA endonuclease activity, producing 5'-phosphomonoesters

ERVK-6 ERVK-7 ERVK-8 PLD6

1.80e-04371534GO:0016891
GeneOntologyMolecularFunctionmolecular carrier activity

KPNA4 KPNA5 KPNA6 EMC10 KPNA2 KPNA3

1.85e-041081536GO:0140104
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

ERVK-6 ERVK-7 ERVK-8 PLD6

4.21e-04461534GO:0016893
GeneOntologyMolecularFunctionRNA stem-loop binding

ERVK-6 ERVK-7 ERVK-8

5.30e-04211533GO:0035613
GeneOntologyMolecularFunctiondisaccharide binding

LGALS9C LGALS9B

1.19e-0371532GO:0048030
GeneOntologyBiologicalProcessNLS-bearing protein import into nucleus

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

3.08e-07201545GO:0006607
GeneOntologyBiologicalProcessviral penetration into host nucleus

KPNA6 KPNA2 KPNA3

1.62e-0641543GO:0075732
GeneOntologyBiologicalProcessmaintenance of animal organ identity

ADGRV1 IQCB1 USH2A

4.04e-0651543GO:0048496
GeneOntologyBiologicalProcessnegative regulation of mammary gland epithelial cell proliferation

GATA3 BRCA2 ROBO1

1.40e-0571543GO:0033600
GeneOntologyBiologicalProcessmammary gland epithelium development

NCOA3 ERBB4 GATA3 SLC12A2 BRCA2 ROBO1

3.95e-05841546GO:0061180
GeneOntologyBiologicalProcessviral process

ERVK-6 SP1 SLC6A19 KPNA6 ERVK-7 ERVK-21 ERVK-9 ERVK-8 ERVK-19 ERVK-24 NOTCH1 KPNA2 KPNA3

4.70e-0546415413GO:0016032
GeneOntologyBiologicalProcessdevelopmental growth

NCOA3 ERBB4 FN1 NLGN4Y NTRK3 UBTFL1 GATA3 ZMIZ1 SIX1 TBL1XR1 BMPR2 NLGN4X SLC12A2 BRCA2 ITSN2 ROBO1 ALCAM MED12 NOTCH1

5.08e-0591115419GO:0048589
GeneOntologyBiologicalProcessnegative regulation of cell proliferation involved in heart valve morphogenesis

BMPR2 NOTCH1

5.54e-0521542GO:0003252
GeneOntologyBiologicalProcessentry of viral genome into host nucleus through nuclear pore complex via importin

KPNA6 KPNA2

5.54e-0521542GO:0075506
GeneOntologyBiologicalProcessprotein localization to organelle

KPNA4 KPNA5 ERBB4 KALRN SYNE1 PEX14 KPNA6 TEX15 HUWE1 CUBN SIX1 SPAG5 PTPN5 BRCA2 INTS13 EMC10 SIX2 NOTCH1 PCM1 KPNA2 KPNA3

6.34e-05109115421GO:0033365
GeneOntologyBiologicalProcessintracellular transport of virus

KPNA6 KPNA2 KPNA3

6.45e-05111543GO:0075733
GeneOntologyBiologicalProcessmulticellular organismal reproductive process

DNHD1 SP1 BRIP1 SPATA31E1 KALRN NLGN4Y SYNE1 SPATA31C2 KPNA6 RSPH6A TEX15 ZMIZ1 SPATA31C1 FANCA BMPR2 NLGN4X BRCA2 TMF1 PLD6 SPACA5 HERC2 NOTCH1

7.95e-05119415422GO:0048609
GeneOntologyBiologicalProcessdevelopmental growth involved in morphogenesis

FN1 NTRK3 SIX1 BMPR2 SLC12A2 ITSN2 ROBO1 ALCAM MED12 NOTCH1

8.62e-0529915410GO:0060560
GeneOntologyBiologicalProcessprotein localization to nucleus

KPNA4 KPNA5 SYNE1 KPNA6 SIX1 PTPN5 INTS13 SIX2 NOTCH1 KPNA2 KPNA3

8.98e-0536215411GO:0034504
GeneOntologyBiologicalProcessanatomical structure formation involved in morphogenesis

ERVK-6 SP1 GATAD2A FN1 GATA3 ETS1 ETS2 RNF213 ERVK-21 ERVK-9 SIX1 HPSE BMPR2 DLC1 SLC12A2 PRCP ERVK-8 TMF1 ROBO1 EMC10 ERVK-19 ENPEP SIX2 MED12 NOTCH1

1.03e-04148315425GO:0048646
GeneOntologyBiologicalProcessDNA integration

ERVK-6 ERVK-7 ERVK-8

1.10e-04131543GO:0015074
GeneOntologyBiologicalProcessprotein import into nucleus

KPNA4 KPNA5 KPNA6 PTPN5 SIX2 NOTCH1 KPNA2 KPNA3

1.11e-041951548GO:0006606
GeneOntologyBiologicalProcessimport into nucleus

KPNA4 KPNA5 KPNA6 PTPN5 SIX2 NOTCH1 KPNA2 KPNA3

1.37e-042011548GO:0051170
GeneOntologyBiologicalProcessresponse to mercury ion

FN1 GATM ALAD

1.40e-04141543GO:0046689
GeneOntologyBiologicalProcessterritorial aggressive behavior

NLGN4Y NLGN4X

1.65e-0431542GO:0002124
GeneOntologyBiologicalProcessregulation of cell proliferation involved in heart valve morphogenesis

BMPR2 NOTCH1

1.65e-0431542GO:0003250
GeneOntologyBiologicalProcesscell proliferation involved in heart valve morphogenesis

BMPR2 NOTCH1

1.65e-0431542GO:0003249
GeneOntologyBiologicalProcesspromoter clearance during DNA-templated transcription

RPRD1B RPRD1A

1.65e-0431542GO:0001109
GeneOntologyBiologicalProcessRNA polymerase II promoter clearance

RPRD1B RPRD1A

1.65e-0431542GO:0001111
GeneOntologyBiologicalProcessnegative regulation of natural killer cell activation

LGALS9C LGALS9B CLNK

1.74e-04151543GO:0032815
GeneOntologyBiologicalProcessmammary gland development

NCOA3 ERBB4 KALRN GATA3 SLC12A2 BRCA2 ROBO1

2.19e-041621547GO:0030879
GeneOntologyBiologicalProcesstube morphogenesis

NCOA3 SP1 GATAD2A FN1 GATA3 ETS1 RNF213 ZMIZ1 SIX1 HPSE BMPR2 DLC1 SLC12A2 PRCP ROBO1 EMC10 ENPEP SIX2 MED12 NOTCH1

2.76e-04112515420GO:0035239
GeneOntologyBiologicalProcesstube development

NCOA3 SP1 BRIP1 GATAD2A FN1 GATA3 ETS1 RNF213 ZMIZ1 SIX1 HPSE BMPR2 LIPA DLC1 SLC12A2 PRCP ROBO1 EMC10 ENPEP SDC1 SIX2 MED12 NOTCH1

2.99e-04140215423GO:0035295
GeneOntologyBiologicalProcesspositive regulation of ureteric bud formation

GATA3 SIX1

3.29e-0441542GO:0072107
GeneOntologyBiologicalProcessregulation of ureteric bud formation

GATA3 SIX1

3.29e-0441542GO:0072106
GeneOntologyBiologicalProcessnegative regulation of cell proliferation involved in heart morphogenesis

BMPR2 NOTCH1

3.29e-0441542GO:2000137
GeneOntologyBiologicalProcessnegative regulation of natural killer cell degranulation

LGALS9C LGALS9B

3.29e-0441542GO:0043322
GeneOntologyBiologicalProcessmale courtship behavior

NLGN4Y NLGN4X

3.29e-0441542GO:0008049
GeneOntologyBiologicalProcesscell proliferation involved in heart valve development

BMPR2 NOTCH1

3.29e-0441542GO:2000793
GeneOntologyBiologicalProcessaortic valve development

GATA3 BMPR2 ROBO1 NOTCH1

3.82e-04461544GO:0003176
GeneOntologyBiologicalProcesscell-cell fusion

ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19

4.41e-04851545GO:0140253
GeneOntologyBiologicalProcesssyncytium formation by plasma membrane fusion

ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19

4.41e-04851545GO:0000768
GeneOntologyBiologicalProcessimmunoglobulin production

SHLD2 IGLV2-33 IGLV2-23 IGLV2-18 IGLV2-14 IGLV2-11 IGLV2-8 IGHD

4.67e-042411548GO:0002377
GeneOntologyBiologicalProcessregulation of cell proliferation involved in heart morphogenesis

SIX1 BMPR2 NOTCH1

4.92e-04211543GO:2000136
GeneOntologyBiologicalProcessregulation of mammary gland epithelial cell proliferation

GATA3 BRCA2 ROBO1

4.92e-04211543GO:0033599
GeneOntologyBiologicalProcessestablishment of protein localization to organelle

KPNA4 KPNA5 PEX14 KPNA6 HUWE1 CUBN PTPN5 BRCA2 SIX2 NOTCH1 KPNA2 KPNA3

5.01e-0451515412GO:0072594
GeneOntologyBiologicalProcesssemi-lunar valve development

GATA3 BMPR2 ROBO1 NOTCH1

5.27e-04501544GO:1905314
GeneOntologyBiologicalProcesssyncytium formation

ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19

5.45e-04891545GO:0006949
GeneOntologyBiologicalProcessregulation of mesonephros development

GATA3 SIX1

5.46e-0451542GO:0061217
GeneOntologyBiologicalProcessnuclear transport

KPNA4 KPNA5 ERVK-6 KPNA6 SMG5 PTPN5 SIX2 NOTCH1 KPNA2 KPNA3

5.63e-0437815410GO:0051169
GeneOntologyBiologicalProcessnucleocytoplasmic transport

KPNA4 KPNA5 ERVK-6 KPNA6 SMG5 PTPN5 SIX2 NOTCH1 KPNA2 KPNA3

5.63e-0437815410GO:0006913
GeneOntologyBiologicalProcessresponse to nutrient

BRIP1 SLC6A19 GATM CUBN F5 LIPA ALAD

6.10e-041921547GO:0007584
GeneOntologyBiologicalProcesscell proliferation involved in heart morphogenesis

SIX1 BMPR2 NOTCH1

6.48e-04231543GO:0061323
GeneOntologyBiologicalProcesstransport of virus

KPNA6 KPNA2 KPNA3

7.36e-04241543GO:0046794
GeneOntologyBiologicalProcesspulmonary valve development

BMPR2 ROBO1 NOTCH1

7.36e-04241543GO:0003177
GeneOntologyCellularComponentNLS-dependent protein nuclear import complex

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

5.48e-09101575GO:0042564
GeneOntologyCellularComponentnucleocytoplasmic transport complex

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

1.70e-08121575GO:0031074
GeneOntologyCellularComponenthost cell

KPNA6 KPNA2 KPNA3

3.38e-0591573GO:0043657
GeneOntologyCellularComponenthost cellular component

KPNA6 KPNA2 KPNA3

1.77e-04151573GO:0018995
GeneOntologyCellularComponentimmunoglobulin complex

IGLV2-33 IGLV2-23 IGLV2-18 IGLV2-14 IGLV2-11 IGLV2-8 IGHD

2.64e-041661577GO:0019814
GeneOntologyCellularComponentsymmetric, GABA-ergic, inhibitory synapse

NLGN4Y NLGN4X

3.33e-0441572GO:0098983
GeneOntologyCellularComponentUSH2 complex

ADGRV1 USH2A

3.33e-0441572GO:1990696
GeneOntologyCellularComponentstereocilia ankle link

ADGRV1 USH2A

8.24e-0461572GO:0002141
GeneOntologyCellularComponentstereocilia ankle link complex

ADGRV1 USH2A

8.24e-0461572GO:0002142
GeneOntologyCellularComponentstereocilium membrane

ADGRV1 USH2A

8.24e-0461572GO:0060171
GeneOntologyCellularComponentpericiliary membrane compartment

ADGRV1 USH2A

8.24e-0461572GO:1990075
GeneOntologyCellularComponentapical plasma membrane

FN1 SLC6A19 CUBN BMPR2 SLC12A2 PTPRH SLC15A1 USH2A MUC4 ENPEP NOTCH1

1.16e-0348715711GO:0016324
GeneOntologyCellularComponentstereocilia coupling link

ADGRV1 USH2A

1.52e-0381572GO:0002139
GeneOntologyCellularComponentcell projection membrane

SLC6A19 ADGRV1 CUBN DLC1 SLC12A2 PTPRH ROBO1 USH2A MUC4 ENPEP

1.59e-0343115710GO:0031253
GeneOntologyCellularComponentinhibitory synapse

ERBB4 NLGN4Y NLGN4X

1.60e-03311573GO:0060077
GeneOntologyCellularComponentapical part of cell

FN1 SLC6A19 CUBN BMPR2 SLC12A2 PTPRH SLC15A1 USH2A MUC4 ENPEP NOTCH1 PCM1

1.75e-0359215712GO:0045177
GeneOntologyCellularComponentinner dynein arm

DNHD1 DNAH12

2.42e-03101572GO:0036156
HumanPhenoRenal insufficiency

BRIP1 FN1 GATA3 GATM CUBN SIX1 F5 FANCA LRIG2 BRCA2 SHPK IQCB1 ROBO1 MED12 MOCOS

8.86e-064215115HP:0000083
DomainArm_3

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

4.57e-1071405PF16186
DomainImporting_su_alpha

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

4.57e-1071405IPR024931
DomainIBB

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

4.57e-1071405PF01749
DomainArm_3

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

4.57e-1071405IPR032413
DomainIBB

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

1.21e-0981405PS51214
DomainImportin-a_IBB

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

2.71e-0991405IPR002652
DomainArm

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

3.20e-06311405PF00514
DomainARM_REPEAT

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

1.17e-05401405PS50176
DomainARM

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

1.17e-05401405SM00185
DomainArmadillo

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

2.62e-05471405IPR000225
DomainARM-like

KPNA4 KPNA5 KPNA6 HEATR5A HUWE1 IQCB1 TARBP1 MED12 KPNA2 KPNA3

3.72e-0527014010IPR011989
DomainTransform_prot_C-ets

ETS1 ETS2

5.58e-0521402IPR016311
DomainNLGN4

NLGN4Y NLGN4X

5.58e-0521402IPR030025
DomainDUF4599

SPATA31E1 SPATA31C2 SPATA31C1

8.63e-05121403PF15371
DomainDUF4599

SPATA31E1 SPATA31C2 SPATA31C1

8.63e-05121403IPR027970
DomainCREPT

RPRD1B RPRD1A

1.67e-0431402IPR032337
DomainCREPT

RPRD1B RPRD1A

1.67e-0431402PF16566
DomainNlgn

NLGN4Y NLGN4X

5.50e-0451402IPR000460
DomainARM-type_fold

KPNA4 KPNA5 KPNA6 HEATR5A HUWE1 IQCB1 TARBP1 KPNA2 KPNA3

1.05e-033391409IPR016024
DomainRNA_pol_II-bd

RPRD1B RPRD1A

1.14e-0371402IPR006903
DomainCTD_bind

RPRD1B RPRD1A

1.14e-0371402PF04818
DomainSIX1_SD

SIX1 SIX2

1.14e-0371402IPR031701
DomainSIX1_SD

SIX1 SIX2

1.14e-0371402PF16878
DomainSpectrin_repeat

KALRN SYNE1 KRT77

1.31e-03291403IPR002017
Domain-

KPNA4 KPNA5 KPNA6 HEATR5A MED12 KPNA2 KPNA3

1.44e-0322214071.25.10.10
DomainERAP1-like_C_dom

TRHDE ENPEP

1.52e-0381402IPR024571
DomainRPR

RPRD1B RPRD1A

1.52e-0381402SM00582
DomainCID_dom

RPRD1B RPRD1A

1.52e-0381402IPR006569
DomainERAP1_C

TRHDE ENPEP

1.52e-0381402PF11838
DomainCID

RPRD1B RPRD1A

1.52e-0381402PS51391
DomainLRRCT

LRIG2 TLR1 CD180

1.74e-03321403PF01463
DomainSPEC

KALRN SYNE1 KRT77

1.74e-03321403SM00150
DomainSpectrin/alpha-actinin

KALRN SYNE1 KRT77

1.74e-03321403IPR018159
DomainGPS

ADGRV1 ADGRE4P ADGRF1

2.08e-03341403SM00303
DomainPAS

NCOA3 KCNH8 ARNT2

2.08e-03341403PS50112
DomainPAS

NCOA3 KCNH8 ARNT2

2.08e-03341403IPR000014
DomainGPS

ADGRV1 ADGRE4P ADGRF1

2.26e-03351403PF01825
DomainGPS

ADGRV1 ADGRE4P ADGRF1

2.46e-03361403PS50221
DomainGPS

ADGRV1 ADGRE4P ADGRF1

2.66e-03371403IPR000203
DomainPNT

ETS1 ETS2

2.94e-03111402PS51433
DomainSAM_PNT

ETS1 ETS2

2.94e-03111402PF02198
DomainPointed_dom

ETS1 ETS2

2.94e-03111402IPR003118
DomainSAM_PNT

ETS1 ETS2

2.94e-03111402SM00251
DomainPeptidase_M1

TRHDE ENPEP

3.51e-03121402IPR001930
DomainCarboxylesterase_B_CS

NLGN4Y NLGN4X

4.12e-03131402IPR019819
DomainPeptidase_M1_N

TRHDE ENPEP

4.12e-03131402IPR014782
DomainPeptidase_M1

TRHDE ENPEP

4.12e-03131402PF01433
DomainCys-rich_flank_reg_C

NTRK3 LRIG2 TLR1 CD180

4.70e-03901404IPR000483
DomainLRRCT

NTRK3 LRIG2 TLR1 CD180

4.70e-03901404SM00082
DomainCARBOXYLESTERASE_B_2

NLGN4Y NLGN4X

4.79e-03141402PS00941
DomainDynein_heavy_dom-2

DNHD1 DNAH12

4.79e-03141402IPR013602
DomainDHC_N2

DNHD1 DNAH12

4.79e-03141402PF08393
DomainCOesterase

NLGN4Y NLGN4X

4.79e-03141402PF00135
DomainCarbesteraseB

NLGN4Y NLGN4X

4.79e-03141402IPR002018
DomainDHC_fam

DNHD1 DNAH12

5.49e-03151402IPR026983
DomainGalectin_CRD

LGALS9C LGALS9B

5.49e-03151402IPR001079
DomainDynein_heavy

DNHD1 DNAH12

5.49e-03151402PF03028
DomainZnf_GATA

GATAD2A GATA3

5.49e-03151402IPR000679
DomainGal-bind_lectin

LGALS9C LGALS9B

5.49e-03151402PF00337
DomainGATA

GATAD2A GATA3

5.49e-03151402PF00320
DomainGal-bind_lectin

LGALS9C LGALS9B

5.49e-03151402SM00908
DomainDynein_heavy_dom

DNHD1 DNAH12

5.49e-03151402IPR004273
DomainGALECTIN

LGALS9C LGALS9B

5.49e-03151402PS51304
DomainGLECT

LGALS9C LGALS9B

5.49e-03151402SM00276
Domain-

LGALS9C LGALS9B ADGRV1 USH2A

5.69e-039514042.60.120.200
DomainCUB

DCBLD1 CUBN ATRNL1

5.90e-03491403PF00431
Domain7tm_2

ADGRV1 ADGRE4P ADGRF1

6.25e-03501403PF00002
DomainG_PROTEIN_RECEP_F2_2

ADGRV1 ADGRE4P ADGRF1

6.25e-03501403PS00650
DomainCUB

DCBLD1 CUBN ATRNL1

6.25e-03501403SM00042
DomainGATA_ZN_FINGER_1

GATAD2A GATA3

6.25e-03161402PS00344
DomainGATA_ZN_FINGER_2

GATAD2A GATA3

6.25e-03161402PS50114
Domain-

DCBLD1 CUBN ATRNL1

6.97e-035214032.60.120.290
DomainCUB

DCBLD1 CUBN ATRNL1

7.35e-03531403PS01180
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-6 ERVK-7 ERVK-21 ERVK-18 ERVK-19

1.82e-125158512629516
Pubmed

Role of the karyopherin pathway in human immunodeficiency virus type 1 nuclear import.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

1.09e-11615858551560
Pubmed

p17 and p17-containing gag precursors of input human immunodeficiency virus are transported into the nuclei of infected cells.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

1.09e-11615852064827
Pubmed

Backbone cyclic peptide, which mimics the nuclear localization signal of human immunodeficiency virus type 1 matrix protein, inhibits nuclear import and virus production in nondividing cells.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

1.09e-11615859548947
Pubmed

The putative alpha helix 2 of human immunodeficiency virus type 1 Vpr contains a determinant which is responsible for the nuclear translocation of proviral DNA in growth-arrested cells.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

1.09e-11615859557700
Pubmed

A role for human immunodeficiency virus type 1 Vpr during infection of peripheral blood mononuclear cells.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

1.09e-11615859603322
Pubmed

CNI-H0294, a nuclear importation inhibitor of the human immunodeficiency virus type 1 genome, abrogates virus replication in infected activated peripheral blood mononuclear cells.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

1.09e-11615859593140
Pubmed

HIV nuclear import is governed by the phosphotyrosine-mediated binding of matrix to the core domain of integrase.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

1.09e-11615857585960
Pubmed

The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

1.09e-11615858041786
Pubmed

The nuclear localization signal of the matrix protein of human immunodeficiency virus type 1 allows the establishment of infection in macrophages and quiescent T lymphocytes.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

1.09e-11615858041734
Pubmed

HIV-1 infection of non-dividing cells: evidence that the amino-terminal basic region of the viral matrix protein is important for Gag processing but not for post-entry nuclear import.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

1.09e-11615859303297
Pubmed

Inhibition of nuclear import by backbone cyclic peptidomimetics derived from the HIV-1 MA NLS sequence.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

1.09e-116158511904219
Pubmed

Phenotype of HIV-1 lacking a functional nuclear localization signal in matrix protein of gag and Vpr is comparable to wild-type HIV-1 in primary macrophages.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

1.09e-11615859918876
Pubmed

HIV-1 infection of nondividing cells: C-terminal tyrosine phosphorylation of the viral matrix protein is a key regulator.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

1.09e-11615857859280
Pubmed

Nuclear localization signal of HIV-1 as a novel target for therapeutic intervention.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

1.09e-11615858529100
Pubmed

Phosphorylation of residue 131 of HIV-1 matrix is not required for macrophage infection.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

1.09e-11615859008157
Pubmed

A synthetic peptide bearing the HIV-1 integrase 161-173 amino acid residues mediates active nuclear import and binding to importin alpha: characterization of a functional nuclear localization signal.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

1.09e-116158515037073
Pubmed

Critical role of reverse transcriptase in the inhibitory mechanism of CNI-H0294 on HIV-1 nuclear translocation.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

1.09e-11615858876228
Pubmed

Role of the basic domain of human immunodeficiency virus type 1 matrix in macrophage infection.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

1.09e-11615857745752
Pubmed

Evidence for direct association of Vpr and matrix protein p17 within the HIV-1 virion.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

1.09e-11615858659115
Pubmed

An actin-regulated importin α/β-dependent extended bipartite NLS directs nuclear import of MRTF-A.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

1.01e-108158520818336
Pubmed

Phosphorylation-dependent human immunodeficiency virus type 1 infection and nuclear targeting of viral DNA.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

1.01e-10815858552640
Pubmed

HIV-1 nuclear import: in search of a leader.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

2.25e-109158510525473
Pubmed

HIV-1 infection requires a functional integrase NLS.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

2.25e-109158511389849
Pubmed

Viral protein R regulates nuclear import of the HIV-1 pre-integration complex.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

2.25e-10915859463369
Pubmed

Reassessment of the roles of integrase and the central DNA flap in human immunodeficiency virus type 1 nuclear import.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

2.25e-109158512414950
Pubmed

Nuclear localization of human immunodeficiency virus type 1 integrase expressed as a fusion protein with green fluorescent protein.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

2.25e-109158510366569
Pubmed

HIV-1 nuclear import: in search of a leader.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

2.25e-10915859366553
Pubmed

Two nuclear localization signals in the HIV-1 matrix protein regulate nuclear import of the HIV-1 pre-integration complex.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

2.25e-109158510860744
Pubmed

Nuclear localization of human immunodeficiency virus type 1 preintegration complexes (PICs): V165A and R166A are pleiotropic integrase mutants primarily defective for integration, not PIC nuclear import.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

2.25e-109158512368302
Pubmed

Cellular distribution and karyophilic properties of matrix, integrase, and Vpr proteins from the human and simian immunodeficiency viruses.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

2.25e-109158511035935
Pubmed

HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

2.25e-10915859275210
Pubmed

The karyophilic properties of human immunodeficiency virus type 1 integrase are not required for nuclear import of proviral DNA.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

2.25e-109158510888652
Pubmed

Active nuclear import of human immunodeficiency virus type 1 preintegration complexes.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

2.25e-10915851631159
Pubmed

A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

2.25e-10915858105392
Pubmed

Characterization of the nuclear import pathway for HIV-1 integrase.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

2.25e-109158511278458
Pubmed

Cloning of two novel human importin-alpha subunits and analysis of the expression pattern of the importin-alpha protein family.

KPNA4 KPNA5 KPNA6 KPNA3

4.10e-10415849395085
Pubmed

HIV-1 p17 and IFN-gamma both induce fructose 1,6-bisphosphatase.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

4.49e-101015859282826
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-8 ERVK-18 ERVK-19 ERVK-25 ERVK-24

5.01e-1094158921542922
Pubmed

HIV-1 nuclear import: matrix protein is back on center stage, this time together with Vpr.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

8.21e-101115859562972
Pubmed

Mutational analysis of cell cycle arrest, nuclear localization and virion packaging of human immunodeficiency virus type 1 Vpr.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

1.40e-091215857494303
Pubmed

Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.

ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19

1.40e-0912158514557543
Pubmed

Inhibition of HIV-1 integrase nuclear import and replication by a peptide bearing integrase putative nuclear localization signal.

KPNA4 KPNA5 KPNA2 KPNA3

2.04e-095158419961612
Pubmed

Plasmodium circumsporozoite protein promotes the development of the liver stages of the parasite.

KPNA4 KPNA5 KPNA6 KPNA3

2.04e-095158417981117
Pubmed

Identification of novel homologues of mouse importin alpha, the alpha subunit of the nuclear pore-targeting complex, and their tissue-specific expression.

KPNA4 KPNA6 KPNA2 KPNA3

2.04e-09515849369227
Pubmed

Heat-shock protein 70 can replace viral protein R of HIV-1 during nuclear import of the viral preintegration complex.

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

5.26e-0915158510964507
Pubmed

Three distinct classes of the alpha-subunit of the nuclear pore-targeting complex (importin-alpha) are differentially expressed in adult mouse tissues.

KPNA4 KPNA6 KPNA2 KPNA3

6.11e-096158410026238
Pubmed

Evidence for distinct substrate specificities of importin alpha family members in nuclear protein import.

KPNA4 KPNA6 KPNA2 KPNA3

1.42e-087158410523667
Pubmed

Active nuclear import and cytoplasmic retention of activation-induced deaminase.

KPNA4 KPNA5 KPNA2 KPNA3

1.42e-087158419412186
Pubmed

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.

ERVK-21 ERVK-9 ERVK-18 ERVK-25 ERVK-24

1.48e-0818158518664271
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

KPNA4 FN1 KALRN PPFIBP1 SYNE1 ETS2 GATM TTC27 KPNA6 SMG5 HUWE1 RAD54L2 FRMD4B RPRD1A ATRNL1 ROBO1 CIPC ALAD HERC2 TARBP1 SNTA1 PCM1 KPNA3

2.12e-0812851582335914814
Pubmed

Importin α7 is essential for zygotic genome activation and early mouse development.

KPNA4 KPNA6 KPNA2 KPNA3

2.83e-088158421479251
Pubmed

Blocking nuclear import of pre-integration complex: an emerging anti-HIV-1 drug discovery paradigm.

KPNA4 KPNA5 KPNA2 KPNA3

2.83e-088158420015032
Pubmed

Changing expression and subcellular distribution of karyopherins during murine oogenesis.

KPNA4 KPNA6 KPNA2 KPNA3

5.08e-089158426399853
Pubmed

Transportin 3 and importin α are required for effective nuclear import of HIV-1 integrase in virus-infected cells.

KPNA4 KPNA5 KPNA2 KPNA3

5.08e-089158421326825
Pubmed

SCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia.

KPNA4 KPNA6 KPNA2 KPNA3

8.43e-0810158435021089
Pubmed

A critical role of Sp1- and Ets-related transcription factors in maintaining CTL-specific expression of the mouse perforin gene.

SP1 ETS1 ETS2

9.20e-08315838871649
Pubmed

Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.

ERVK-6 ERVK-18 ERVK-19

9.20e-083158310516026
Pubmed

Regulation of the human interleukin-5 promoter by Ets transcription factors. Ets1 and Ets2, but not Elf-1, cooperate with GATA3 and HTLV-I Tax1.

GATA3 ETS1 ETS2

9.20e-083158310212281
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

KPNA4 SP1 ERBB4 SPATA31E1 PEX14 RAD54L2 ASAP2 USF3 SLC12A2 NOTCH1 RIC1 KPNA2 KPNA3

9.63e-084301581335044719
Pubmed

The HIV-1 passage from cytoplasm to nucleus: the process involving a complex exchange between the components of HIV-1 and cellular machinery to access nucleus and successful integration.

KPNA4 KPNA5 KPNA2 KPNA3

1.32e-0711158422509482
Pubmed

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Membrane (M) and Spike (S) Proteins Antagonize Host Type I Interferon Response.

KPNA4 KPNA6 KPNA2 KPNA3

2.84e-0713158434950606
Pubmed

Importin α3 regulates chronic pain pathways in peripheral sensory neurons.

KPNA4 KPNA6 KPNA3

3.67e-074158332792398
Pubmed

MERS-CoV 4b protein interferes with the NF-κB-dependent innate immune response during infection.

KPNA4 KPNA2 KPNA3

3.67e-074158329370303
Pubmed

Nuclear import of transcriptional corepressor BCOR occurs through interaction with karyopherin α expressed in human periodontal ligament.

KPNA4 KPNA6 KPNA2

3.67e-074158330396568
Pubmed

Viral and cellular requirements for the nuclear entry of retroviral preintegration nucleoprotein complexes.

KPNA5 KPNA2 KPNA3

3.67e-074158324103892
Pubmed

Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.

ERVK-6 ERVK-7 ERVK-24

3.67e-074158310469592
Pubmed

Molecular determinants for nuclear import of influenza A PB2 by importin α isoforms 3 and 7.

KPNA4 KPNA6 KPNA2

3.67e-074158325599645
Pubmed

Nuclear trafficking of the POZ-ZF protein Znf131.

KPNA6 KPNA2 KPNA3

3.67e-074158317306895
Pubmed

Development of a pipeline for automated, high-throughput analysis of paraspeckle proteins reveals specific roles for importin α proteins.

KPNA4 KPNA6 KPNA2

3.67e-074158328240251
Pubmed

Regulating the functions of the HIV-1 matrix protein.

KPNA4 KPNA5 KPNA2 KPNA3

3.96e-0714158417411366
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

PPFIBP1 SYNE1 URB2 TBL1XR1 FANCA SLC38A10 SLC12A2 PRCP LPCAT3 ITSN2 TMF1 ROBO1 ALCAM HERC2 TARBP1

1.12e-067191581535337019
Pubmed

Activation of C1r by proteolytic cleavage.

IGLV2-33 IGLV2-23 IGLV2-18 IGLV2-14 IGLV2-11

1.52e-064315851249422
Pubmed

Retinoblastoma-binding Protein 4-regulated Classical Nuclear Transport Is Involved in Cellular Senescence.

KPNA5 KPNA2 KPNA3

1.82e-066158326491019
Pubmed

Karyopherin alpha7 (KPNA7), a divergent member of the importin alpha family of nuclear import receptors.

KPNA4 KPNA2 KPNA3

1.82e-066158320701745
Pubmed

Human endogenous retrovirus HERV-K(HML-2) proviruses with Rec protein coding capacity and transcriptional activity.

ERVK-6 ERVK-9 ERVK-19

1.82e-066158315063128
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

KPNA4 KPNA5 PPFIBP1 UGGT1 TTC27 PEX14 KPNA6 URB2 COMMD9 HERC2 RFT1 PCM1 MOCOS KPNA2 KPNA3

2.01e-067541581533060197
Pubmed

Physicochemical and functional characterization of the C1r subunit of the first complement component.

IGLV2-33 IGLV2-23 IGLV2-18 IGLV2-14 IGLV2-11

2.39e-06471585814163
Pubmed

Recognition of immunoglobulins by Fcgamma receptors.

IGLV2-33 IGLV2-23 IGLV2-18 IGLV2-14 IGLV2-11

2.66e-0648158511955599
Pubmed

Sequence and evolution of the human germline V lambda repertoire.

IGLV2-33 IGLV2-18 IGLV2-14 IGLV2-11 IGLV2-8

2.95e-064915858951372
Pubmed

Associations and interactions between Ets-1 and Ets-2 and coregulatory proteins, SRC-1, AIB1, and NCoR in breast cancer.

NCOA3 ETS1 ETS2

3.18e-067158315788656
Pubmed

Nuclear translocation of hypoxia-inducible factors (HIFs): involvement of the classical importin alpha/beta pathway.

KPNA5 KPNA6 KPNA3

5.07e-068158318187047
Pubmed

BIG3 Inhibits the Estrogen-Dependent Nuclear Translocation of PHB2 via Multiple Karyopherin-Alpha Proteins in Breast Cancer Cells.

KPNA5 KPNA6 KPNA2

5.07e-068158326052702
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

KPNA4 UGGT1 TTC27 RNF213 KPNA6 HUWE1 PTPN5 SLC12A2 PTPRH TMF1 ROBO1 CRYBG3 HERC2 SIX2 NOTCH1 KPNA2 KPNA3

6.34e-0610491581727880917
Pubmed

14-3-3 suppresses the nuclear localization of threonine 157-phosphorylated p27(Kip1).

KPNA4 KPNA5 KPNA3

7.57e-069158315057270
Pubmed

Conserved overlapping gene arrangement, restricted expression, and biochemical activities of DNA polymerase ν (POLN).

BRIP1 FANCA BRCA2

7.57e-069158326269593
Pubmed

Cellular cofactors of lentiviral integrase: from target validation to drug discovery.

KPNA4 KPNA6 KPNA2

7.57e-069158322928108
Pubmed

Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.

ERVK-6 ERVK-21 ERVK-19

1.08e-0510158312970426
Pubmed

Importin alpha/beta mediates nuclear transport of a mammalian circadian clock component, mCRY2, together with mPER2, through a bipartite nuclear localization signal.

KPNA4 KPNA6 KPNA2

1.08e-0510158315689618
Pubmed

One-megabase sequence analysis of the human immunoglobulin lambda gene locus.

IGLV2-33 IGLV2-23 IGLV2-18 IGLV2-14 IGLV2-11 IGLV2-8

1.10e-0510915869074928
Pubmed

CTCF tethers an insulator to subnuclear sites, suggesting shared insulator mechanisms across species.

KPNA4 KPNA2 KPNA3

1.96e-0512158314759373
Pubmed

Transcriptional regulation of telomerase activity: roles of the the Ets transcription factor family.

ETS1 ETS2

2.05e-052158217986575
Pubmed

Analysis of the mutational status of SIX1/2 and microRNA processing genes in paired primary and relapsed Wilms tumors and association with relapse.

SIX1 SIX2

2.05e-052158233281191
Pubmed

Heparanase regulates levels of syndecan-1 in the nucleus.

HPSE SDC1

2.05e-052158219305494
Pubmed

ETS-1 and ETS-2 are upregulated in a transgenic mouse model of pigmented ocular neoplasm.

ETS1 ETS2

2.05e-052158218958307
Pubmed

Ets-1 and Ets-2 protooncogene expression in theca cells of the adult mouse ovary.

ETS1 ETS2

2.05e-05215821511734
Pubmed

Development of an autism severity score for mice using Nlgn4 null mutants as a construct-valid model of heritable monogenic autism.

NLGN4Y NLGN4X

2.05e-052158223183221
Pubmed

Juvenile manifestation of ultrasound communication deficits in the neuroligin-4 null mutant mouse model of autism.

NLGN4Y NLGN4X

2.05e-052158224855039
Pubmed

Genetic variants in fanconi anemia pathway genes BRCA2 and FANCA predict melanoma survival.

FANCA BRCA2

2.05e-052158225243787
Pubmed

Heparanase-enhanced Shedding of Syndecan-1 and Its Role in Driving Disease Pathogenesis and Progression.

HPSE SDC1

2.05e-052158232623935
InteractionPPP4R1L interactions

BRIP1 TBL1XR1 DMXL1 FANCA BRCA2 IQCB1 MED12 MOCOS

1.82e-07871428int:PPP4R1L
InteractionBRCA1 interactions

DNHD1 NCOA3 SP1 BRIP1 RBBP5 UGGT1 GATA3 ETS1 ETS2 KPNA6 ZMIZ1 HUWE1 RAD54L2 CUBN TBL1XR1 SPAG5 RPRD1B FANCA RPRD1A BRCA2 HERC2 USH2A MED12 KPNA2 KPNA3

1.99e-06124914225int:BRCA1
InteractionHDAC1 interactions

KPNA4 SP1 GATAD2A FN1 RBBP5 GATA3 ETS1 TTC27 PEX14 KPNA6 ZMIZ1 TBL1XR1 SPAG5 USP38 BRCA2 TMF1 CRYBG3 MED12 NOTCH1 PCM1 KPNA2 KPNA3

1.01e-05110814222int:HDAC1
InteractionETS1 interactions

NCOA3 SP1 GATA3 ETS1 ETS2 ZMIZ1 HUWE1

2.40e-051211427int:ETS1
InteractionEPAS1 interactions

KPNA5 SP1 ETS1 KPNA6 RPRD1B ARNT2 MED12 KPNA3

3.17e-051731428int:EPAS1
InteractionFBXO2 interactions

FN1 ADGRV1 ERVMER34-1 HPSE LRIG2 LIPA PRCP IQCB1 ROBO1 ALCAM ADGRF1 NOTCH1

3.53e-0541114212int:FBXO2
Cytoband22q11.2

IGLV2-33 IGLV2-23 IGLV2-18 IGLV2-14 IGLV2-11 IGLV2-8

3.85e-06120157622q11.2
Cytoband10p15

GATA3 ITIH2

2.41e-047157210p15
GeneFamilyArmadillo repeat containing|Importins

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

3.42e-0818985596
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

KPNA4 KPNA5 KPNA6 KPNA2 KPNA3

3.45e-0643985409
GeneFamilyImmunoglobulin lambda locus at 22q11.2

IGLV2-33 IGLV2-23 IGLV2-18 IGLV2-14 IGLV2-11 IGLV2-8

8.78e-0689986353
GeneFamilyRing finger proteins|Fanconi anemia complementation groups|Protein phosphatase 1 regulatory subunits|BRCA1 A complex|BRCA1 B complex|BRCA1 C complex

BRIP1 FANCA BRCA2

1.65e-0420983548
GeneFamilyFibronectin type III domain containing|USH2 complex

ADGRV1 USH2A

1.73e-0449821244
GeneFamilySINE class homeoboxes

SIX1 SIX2

4.30e-046982525
GeneFamilyFibronectin type III domain containing

FN1 KALRN PTPRH ROBO1 USH2A

1.79e-03160985555
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

GATAD2A GATA3

2.92e-031598282
GeneFamilyGalectins

LGALS9C LGALS9B

2.92e-0315982629
CoexpressionGSE42021_CD24HI_VS_CD24INT_TCONV_THYMUS_UP

SYNE1 GATA3 ETS2 MARCHF7 ZMIZ1 DLC1 RPRD1A ALCAM

1.55e-052001448M9591
CoexpressionGSE27670_CTRL_VS_BLIMP1_TRANSDUCED_GC_BCELL_DN

SIX1 BMPR2 COMMD9 ALCAM ENPEP SDC1 SIX2 CD200

1.55e-052001448M8208
CoexpressionBROWNE_HCMV_INFECTION_30MIN_DN

KALRN CUBN RGS3 DMXL1 BRCA2 ITSN2 MUC4

1.60e-051451447M0
CoexpressionMATHEW_FANCONI_ANEMIA_GENES

BRIP1 FANCA BRCA2

2.59e-05111443M12972
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FN1 PPFIBP1 ETS1 ETS2 RNF213 BMPR2 ASAP2 DLC1 PRCP CD200

1.54e-09200149102d07237022b409c4fac6fcf99b68c8affb3007cd
ToppCellLPS_only-Endothelial-Endothelial-Activated_Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

ETS1 ETS2 RNF213 BMPR2 DLC1 SLC12A2 PRCP ALCAM CD200

2.58e-082001499edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCellLPS_IL1RA-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ETS1 ETS2 RNF213 BMPR2 ASAP2 DLC1 SLC12A2 PRCP CD200

2.58e-0820014995c092b2ecc081b5d04476c56333c338cd89ab984
ToppCellLPS_IL1RA-Endothelial-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ETS1 ETS2 RNF213 BMPR2 ASAP2 DLC1 SLC12A2 PRCP CD200

2.58e-08200149972ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ERBB4 NTRK3 ATP13A5 RSPH6A ADGRV1 F5 USH2A HYDIN

7.69e-081621498bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellCOVID_non-vent-Lymphocytic-Plasma_cell-IgA_Plasmablast|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

NCOA3 IGLV2-23 IGLV2-18 IGLV2-14 IGLV2-11 IGLV2-8 CD180 SDC1

3.44e-071971498fdbf4eb9fa5aefb4ffb307494fe4774bf5e0aaeb
ToppCellkidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A19 CUBN SLC38A10 SLC15A1 PRCP ALCAM SDC1

5.97e-07145149747a3bb973a508d3097213a2d86ad1ce697af9bae
ToppCellBAL-Mild-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

URB2 IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8 IQCB1 SDC1

9.77e-0715614975d9e1df70f2e9219f6b029be2e39297605d36726
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IP6K3 FRMD4B SLC12A2 PTPRH TLR1 ADGRE4P SNTA1

1.48e-06166149791eeb48680dd07ae4115afacdc0a8f6fa18885e5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FN1 SYNE1 NTRK3 GATA3 ETS1 DLC1 ROBO1

1.88e-06172149708a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FN1 SYNE1 NTRK3 GATA3 ETS1 DLC1 ROBO1

1.88e-061721497553701349444eb366df3c11f54bb093434f153c6
ToppCellControl-Lymphoid_P|Control / Disease group, lineage and cell class

IGLV2-33 IGLV2-23 IGLV2-18 IGLV2-14 IGLV2-11 IGLV2-8 SDC1

2.19e-061761497d895a6b295cd649273ff80ad7785a3e0ae4c728a
ToppCellControl-Lymphoid_P-Plasmablast|Control / Disease group, lineage and cell class

IGLV2-33 IGLV2-23 IGLV2-18 IGLV2-14 IGLV2-11 IGLV2-8 SDC1

2.19e-0617614974b4416f342b732d2cc60133838728880326257d8
ToppCellCV-Severe-7|CV / Virus stimulation, Condition and Cluster

NCOA3 KALRN NLGN4Y UGGT1 RNF213 HUWE1 PCM1

2.19e-0617614973de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IGLV2-33 IGLV2-23 IGLV2-18 IGLV2-14 IGLV2-11 IGLV2-8 SDC1

2.27e-0617714974c434a7b7cc54cf4dac996bbc3f5124d9ef9a9cd
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

NCOA3 KALRN NLGN4Y UGGT1 RNF213 HUWE1 PCM1

2.27e-06177149782fdd6185b368f54f03de389427cbe3071d21a99
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGLV2-33 IGLV2-23 IGLV2-18 IGLV2-14 IGLV2-11 IGLV2-8 SDC1

2.27e-061771497d746122bf8d208c3aa4d156e8c12d0a0e555c6e5
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGLV2-33 IGLV2-23 IGLV2-18 IGLV2-14 IGLV2-11 IGLV2-8 SDC1

2.27e-061771497fc40918825b7e1eb6861df59dfca944778a64b98
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-1|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NCOA3 GATM DNAH12 IGHD CD180 CCDC191 CD200

2.36e-061781497812e261d9cbdc74fafe3c5c3422151c1cfacb22d
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGLV2-33 IGLV2-23 IGLV2-18 IGLV2-14 IGLV2-11 IGLV2-8 SDC1

2.45e-061791497837ed81f18257f444eaeadc4fac89deedd4e3061
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGLV2-33 IGLV2-23 IGLV2-18 IGLV2-14 IGLV2-11 IGLV2-8 SDC1

2.45e-061791497494febe77c6d4e6a2c6f0928bbf4c84b0301f188
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGLV2-33 IGLV2-23 IGLV2-18 IGLV2-14 IGLV2-11 IGLV2-8 SDC1

2.45e-061791497b6ee4f41d8fb5f047b7bdd8489dda0a89fc6d43f
ToppCell10x5'-Lung-Lymphocytic_B|Lung / Manually curated celltypes from each tissue

KCNH8 IGLV2-14 IGLV2-11 IGLV2-8 NLGN4X IGHD CD200

2.73e-061821497310f94437d197eaaaf6e30e68063b33e94befe77
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

TRHDE MACC1 GATM CUBN SLC15A1 ENPEP HYDIN

2.83e-0618314976878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-4|TCGA-Thryoid / Sample_Type by Project: Shred V9

CDC42BPG MACC1 GATAD2A FN1 SMG5 HPSE RPRD1A

2.93e-061841497d9659d1e4465fec68f48a22edef443f354f6c7cf
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

MACC1 PPFIBP1 GATM CUBN FRMD4B ENPEP HYDIN

2.93e-06184149751ed1ebfdef45149541917c66cbacad87072e51f
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-Plasma_B-Plasma_B-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8 IGHD SDC1 MOCOS

3.04e-06185149796423bdcf0e85ca41370f79347d27c22f3de98f5
ToppCellLA-07._Pericyte|LA / Chamber and Cluster_Paper

KALRN ETS1 DCBLD1 LIPA DLC1 SLC12A2 ENPEP

3.04e-061851497ba5baa4d7f097108622674de5b7f4fd279843d24
ToppCell10x5'v1-week_12-13-Lymphocytic_NK-T_NK-mature_NK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

LGALS9C PRR5L LGALS9B SYNE1 GATA3 ETS1 RNF213

3.15e-061861497165d02be3b3eaeb8784a2b0b2020928b21a19bc7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN SYNE1 NTRK3 GATA3 ETS1 DLC1 ROBO1

3.27e-06187149715d6e158562d7d85af3ceaf955439b379c8fce81
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN SYNE1 NTRK3 GATA3 ETS1 DLC1 ROBO1

3.27e-061871497f62074b631fd45ad299c69d71b09267b04d656ee
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN SYNE1 NTRK3 GATA3 ETS1 DLC1 ROBO1

3.38e-06188149732f22a4d8cb98fd8b8fa0fbf28ef9266d711d081
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MACC1 ERBB4 KCNH8 NLGN4Y RNF213 ALCAM HYDIN

3.50e-061891497aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MACC1 ERBB4 KCNH8 NLGN4Y RNF213 ALCAM HYDIN

3.50e-0618914978977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCellLPS_only-Endothelial-Endothelial-Activated_Alv_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ETS1 BMPR2 DLC1 SLC12A2 PRCP ALCAM CD200

3.75e-061911497a7b18bcf27c38ad2353c239ecb309c80f3ef3359
ToppCellCOVID-19-lung-Secretory|COVID-19 / Disease (COVID-19 only), tissue and cell type

MACC1 ERBB4 ADGRV1 SIX1 ALCAM MUC4 SDC1

3.89e-06192149759261098ccb52306f837f632ebaea45b90ad30fe
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

DNHD1 IGLV2-23 IGLV2-18 IGLV2-14 IGLV2-11 IGLV2-8 CD180

3.89e-0619214973dddfc93c3c954c4416c7c1f1f161e4d1dcc1233
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE MACC1 ERBB4 SYNE1 RNF213 ADGRF1 HYDIN

4.16e-061941497e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell5'-Adult-LargeIntestine|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRR5L IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8 MUC4 SDC1

4.30e-061951497600174e35574fe7c44dd923adcf43686e7b01e39
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN PPFIBP1 ETS1 ETS2 BMPR2 DLC1 CD200

4.30e-061951497818bc18c5834238e5f733cac6fe928ed0788f57d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN PPFIBP1 ETS1 ETS2 BMPR2 DLC1 CD200

4.45e-0619614977cbb19108b4553ef60ef5c230a29de1662c02efe
ToppCellCOVID-19-lung-Capillary_Aerocytes|lung / Disease (COVID-19 only), tissue and cell type

NCOA3 KALRN PPFIBP1 SYNE1 ETS1 BMPR2 SLC12A2

4.45e-0619614974ac4073380d939a73cec7413e9f3f5ef616d2924
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FN1 KALRN SYNE1 NTRK3 DLC1 ATRNL1 ROBO1

4.60e-0619714979b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MACC1 DNAH12 ALCAM ADGRF1 MUC4 HYDIN PCM1

4.76e-061981497d0ecace1fad24ce50b0935036fabb07e6c9e372d
ToppCellSepsis-Leuk-UTI-Lymphocyte-B-B_naive|Leuk-UTI / Disease, condition lineage and cell class

KCNH8 IGLV2-23 IGLV2-14 IGLV2-8 IGHD CD180 CD200

4.92e-061991497f93efc7d4c4a40d65fa10b53a2da6d961930f7d2
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

NCOA3 ETS1 ETS2 RNF213 BMPR2 SLC12A2 CD200

5.08e-06200149779e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCellLPS_anti-TNF-Endothelial|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ETS1 ETS2 BMPR2 ASAP2 SLC12A2 PRCP CD200

5.08e-0620014971d105eeda5a2c51f9a4654ffc79b7e2348ad593b
ToppCellLPS_anti-TNF-Endothelial-Endothelial|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ETS1 ETS2 BMPR2 ASAP2 SLC12A2 PRCP CD200

5.08e-06200149760d2cbf41f37f1b11eddb4c9d9246c9c1fc5a5af
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ETS1 ETS2 RNF213 BMPR2 DLC1 PRCP CD200

5.08e-0620014973585484c7e24e941708bee471ca607d8ccee74e6
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / Treatment groups by lineage, cell group, cell type

ETS1 ETS2 BMPR2 DLC1 SLC12A2 PRCP CD200

5.08e-0620014974bb609a284d4e6066f17470a1736076aa4a1f84c
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ETS1 RNF213 BMPR2 ASAP2 DLC1 PRCP NOTCH1

5.08e-062001497dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellLPS_only-Endothelial-Endothelial-Activated_Gen_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

ETS1 ETS2 RNF213 BMPR2 DLC1 PRCP CD200

5.08e-0620014976f531a418ff25b59a543800cf4bce7b72404ce08
ToppCellLPS_only-Endothelial|LPS_only / Treatment groups by lineage, cell group, cell type

ETS1 ETS2 BMPR2 DLC1 SLC12A2 PRCP CD200

5.08e-06200149781e76508c9050d533853d5fd2f3097b27613d836
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ETS1 ETS2 RGS3 BMPR2 DLC1 PRCP CD200

5.08e-062001497f15fffefe372005c33e31845982e2d2714ac26af
ToppCellTCGA-Uvea-Primary_Tumor-Uveal_Melanoma-Spindle_Cell-2|TCGA-Uvea / Sample_Type by Project: Shred V9

ERBB4 USF3 TLR1 IQCB1 ROBO1 CCDC191

6.58e-061361496b460669c13ed43ff3885acd38ce18f75d693738d
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERBB4 ATP13A5 ADGRV1 ADGRF1 USH2A HYDIN

9.49e-06145149696712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellhealthy_donor-Lymphocytic-Plasma_cell-IgG_Plasmablast|healthy_donor / Disease condition, Lineage, Cell class and subclass

IGLV2-33 IGLV2-23 IGLV2-18 IGLV2-11 IGLV2-8 SDC1

1.24e-051521496a2ba2d95ac9010e1a62db34dcad10d004f8a90cc
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_4|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

MACC1 NTRK3 TRIM54 F5 USF3 CD200

1.34e-0515414961f8d127b657976656e4ec292f26d619943533b86
ToppCellBAL-Mild-Lymphocyte-B-Plasmablast-Plasmablast-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8 IQCB1 SDC1

1.55e-0515814961397078f909338fa5fa3b01748db891e5e3fc9e7
ToppCellBAL-Mild-Lymphocyte-B-Plasmablast|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8 IQCB1 SDC1

1.55e-051581496e5451cfe67e882eb0c1eca287740f8ab75370abc
ToppCellBAL-Mild-Lymphocyte-B-Plasmablast-Plasmablast|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8 IQCB1 SDC1

1.55e-05158149617a13c5719eb363f2eb8f1d4e171429c6a1ce1e9
ToppCellBAL-Mild-Lymphocyte-B-Plasmablast-Plasmablast|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8 IQCB1 SDC1

1.60e-0515914966ecc3cb2daa5887b59836842be414a00cdcdaeec
ToppCellnormal_Lung-B_lymphocytes-MALT_B_cells|normal_Lung / Location, Cell class and cell subclass

IGLV2-18 IGLV2-14 IGLV2-11 IGLV2-8 IGHD SDC1

1.60e-051591496fbd0131b66f4267f7b0d6c3ad874ad097b859074
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 NTRK3 GATA3 ETS1 DLC1 ROBO1

1.60e-0515914965ca96db4281abb5f646150ccf36adc66ab201c78
ToppCellBAL-Mild-Lymphocyte-B-Plasmablast|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8 IQCB1 SDC1

1.60e-0515914961827493fb464bbddb2ee23f99472cfbcaf57405b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FN1 NTRK3 GATA3 ETS1 DLC1 ROBO1

1.72e-0516114961b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DNHD1 SLC15A1 ALAD ALCAM MUC4 SDC1

1.78e-051621496e0417f1242edf71934fe62bccc55c4678f7ff4ac
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DNHD1 SLC15A1 ALAD ALCAM MUC4 SDC1

1.78e-0516214968e0f03fcc25b2ea777e8478fbf771699cf93719c
ToppCellMild_COVID-19-B_cell-Plasmablast|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8 IQCB1 SDC1

1.78e-051621496b67f6fb3d7f6093c8ef02398ff8fea4d0fb41a3b
ToppCelldroplet-Thymus-nan-21m-Myeloid-Plasma_cells_and_B_cells|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EVI2A CUBN HPSE IQCB1 ALCAM SDC1

1.98e-05165149621a82a975f550080b6674750b06212205cd16742
ToppCellLV-16._Neuronal|World / Chamber and Cluster_Paper

KCNH8 TMEM132B ASAP2 DLC1 NLGN4X ALCAM

1.98e-0516514966ed52cb756d21addf46c7f6c457458b01339fe04
ToppCellhealthy_donor-Lymphocytic-Plasma_cell-IgM_Plasmablast|healthy_donor / Disease condition, Lineage, Cell class and subclass

IGLV2-23 IGLV2-18 IGLV2-14 IGLV2-11 IGLV2-8 SDC1

2.05e-0516614962b7b580bec8d9467b0deaf97098065f72dbf2a4f
ToppCell10x5'-GI_large-bowel|World / Manually curated celltypes from each tissue

IGLV2-33 IGLV2-23 IGLV2-18 IGLV2-11 IGLV2-8 SDC1

2.19e-0516814961290c909655bc37f6b8bf216d18127a21b99e9c0
ToppCellLA-16._Neuronal|LA / Chamber and Cluster_Paper

KCNH8 TMEM132B DLC1 NLGN4X CIPC ALCAM

2.19e-051681496c55bbfbde8bb954f1cb9af82007bdd1f8070fee3
ToppCellBAL-Mild-Lymphocyte-B|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KCNH8 IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8 IGHD

2.26e-051691496307571e57c3bfdf15f0fe1a8b36585e8e4f8a207
ToppCellLV-16._Neuronal|LV / Chamber and Cluster_Paper

KCNH8 TMEM132B ASAP2 DLC1 NLGN4X ALCAM

2.26e-051691496a8fc8ab0f0757e939e213efb61c03cfe390bf7d2
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 NTRK3 GATA3 ETS1 DLC1 ROBO1

2.34e-051701496876b84740e15399bfff2b9c7f0b80fd759bbdb3f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 NTRK3 GATA3 ETS1 DLC1 ROBO1

2.34e-0517014961f8738acf439d893880db7e1fdc9b3615ca00c39
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BRIP1 FN1 FANCA DLC1 BRCA2 ATRNL1

2.42e-051711496b0373ed8283ee1792b6a490bff93906546978593
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BRIP1 FN1 FANCA DLC1 BRCA2 ATRNL1

2.42e-051711496b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCell10x5'-Lung-Lymphocytic_B-Memory_B_cells|Lung / Manually curated celltypes from each tissue

KCNH8 IGLV2-14 IGLV2-11 IGLV2-8 NLGN4X ATRNL1

2.50e-0517214962cb2dc7cfd6db5a98a393b1a84c23abf3d692a53
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RBBP5 TBL1XR1 TEX22 ASAP2 MUC4 MOCOS

2.67e-05174149642f2ba54b4ea4c62482582b0ccdadffae0a5eb4a
ToppCellCOVID-19-kidney-REN+Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

KALRN NTRK3 GATA3 ETS1 DLC1 ROBO1

2.67e-0517414968393f0b43c767839c1630bcb952d62b42efc788d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ATP13A5 SIX1 C4orf54 CRYBG3 CLNK ADGRF1

2.84e-051761496cb21342dd135cc80a50aafe7bf8bf31265db68dd
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-Plasma_B-Plasma_B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8 IGHD SDC1

2.84e-05176149667d6dc38708692f8c58cea5ed896f10718e9ffa6
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-Plasma_B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8 IGHD SDC1

2.84e-051761496125be81311f87563ca321472fcce6e0e0ae24c16
ToppCell10x5'v1-week_17-19-Lymphocytic_NK-T_NK-mature_NK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

LGALS9C PRR5L LGALS9B SYNE1 GATA3 ETS1

2.94e-0517714960f2616a81f8fbede77c860b2126e3fa826672da3
ToppCelldroplet-Marrow-nan-21m-Myeloid-monocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FN1 EVI2A HPSE LIPA PRCP ADGRE4P

2.94e-051771496b860013f1fd397400a62d66ab521cfc81349ffe2
ToppCellControl-Lymphocyte-B-B_naive|Control / Disease, Lineage and Cell Type

IGLV2-23 IGLV2-14 IGHD CD180 CCDC191 CD200

3.13e-05179149635994281904bfe38766e715ab608211a5ca865a9
ToppCellCOVID-19-kidney-REN+Pericyte|kidney / Disease (COVID-19 only), tissue and cell type

FN1 KALRN NTRK3 ETS1 DLC1 ROBO1

3.13e-051791496342c1cc4444f51b8dcb30d3adc98285a25669c6e
ToppCellcellseq2-Epithelial-Epithelial_Airway-Basal/Suprabasal-Suprabasal|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LGALS9C LGALS9B ADGRF1 MUC4 SDC1 SIX2

3.22e-051801496535a890bde0d978b461c2d4c571529b585c76b21
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGLV2-23 IGLV2-18 IGLV2-14 IGLV2-11 IGLV2-8 IGHD

3.22e-051801496cea079bc02e08c46600eed05ab9924ec90e1e3d3
ToppCellLeuk-UTI-Lymphocyte-B-B_naive|Leuk-UTI / Disease, Lineage and Cell Type

IGLV2-23 IGLV2-14 IGLV2-8 IGHD CD180 CD200

3.33e-051811496fb0b5a94796b99c64091f9890f7a09c39bbc3f73
ToppCellPCW_05-06-Neuronal-Neuronal_SCP|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ERBB4 KCNH8 GATM ADGRV1 TMEM132B NLGN4X

3.43e-051821496b4fc5e4f5d8440a3c9ee0a6fd0da87b43cabc8c6
ToppCellLV-07._Pericyte|World / Chamber and Cluster_Paper

KALRN DCBLD1 LIPA DLC1 SLC12A2 ENPEP

3.54e-051831496273db6a3b00a93ca852498471187b642b5368185
ToppCellLA-07._Pericyte|World / Chamber and Cluster_Paper

KALRN DCBLD1 LIPA DLC1 SLC12A2 ENPEP

3.54e-051831496e3835db4795362b0442d5893baf2a78efcc20428
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE KALRN ADGRV1 ROBO1 USH2A HYDIN

3.65e-0518414962cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE KALRN ADGRV1 ROBO1 USH2A HYDIN

3.65e-0518414962b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGLV2-23 IGLV2-18 IGLV2-14 IGLV2-11 IGLV2-8 IGHD

3.65e-05184149615f2c10101ccc8ed059520fc082ee42593dff269
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGLV2-23 IGLV2-18 IGLV2-14 IGLV2-11 IGLV2-8 IGHD

3.65e-051841496a90a58d9e319afa1cd572e4c2f516fadc42f56e5
DrugHcda

KPNA4 KPNA5 KPNA2 KPNA3

1.02e-0781434CID005312573
DrugTat11

KPNA4 KPNA5 KPNA2 KPNA3

1.83e-0791434CID000480142
DrugHYCRON linker

KPNA4 KPNA5 KPNA3

2.40e-0651433CID011069636
DrugCNI-H0294

KPNA4 KPNA5 KPNA3

2.40e-0651433CID000073088
DrugAC1LA3FM

KPNA4 KPNA5 KPNA3

4.79e-0661433CID000480797
DrugdmDBP

KPNA4 KPNA2 KPNA3

4.79e-0661433CID005316801
DrugLysylproline

SP1 SYNE1 PTPN5 SLC15A1 ENPEP

1.26e-05481435CID000171204
DiseaseMalignant neoplasm of breast

KPNA5 NCOA3 ERBB4 BRIP1 FN1 KALRN SYNE1 GATA3 ETS2 ZMIZ1 CUBN HPSE BMPR2 RPRD1A BRCA2 ITSN2 ROBO1 HERC2 ENPEP MED12 NOTCH1 DOP1A

5.09e-09107413722C0006142
DiseaseNeoplasm of uncertain or unknown behavior of breast

ERBB4 BRIP1 GATA3 BRCA2 HERC2 NOTCH1

3.53e-08411376C0496956
DiseaseBreast adenocarcinoma

ERBB4 BRIP1 GATA3 BRCA2 HERC2 NOTCH1

3.53e-08411376C0858252
DiseaseBreast Carcinoma

NCOA3 ERBB4 BRIP1 FN1 SYNE1 GATA3 ETS2 HPSE BMPR2 BRCA2 ITSN2 HERC2 MED12 NOTCH1

2.31e-0753813714C0678222
DiseasePancytopenia

BRIP1 FANCA BRCA2 MOCOS

6.14e-06261374C0030312
Diseaseuric acid measurement

CDC42BPG SHLD2 ERBB4 TTC27 ADGRV1 ZMIZ1 CUBN F5 FANCA BMPR2 ASAP2 RFT1

2.91e-0561013712EFO_0004761
DiseaseFanconi anemia

BRIP1 FANCA BRCA2

3.43e-05141373cv:C0015625
DiseaseMammary Carcinoma, Human

NCOA3 BRIP1 FN1 SYNE1 ETS2 HPSE BMPR2 BRCA2 ITSN2 MED12 NOTCH1

3.59e-0552513711C4704874
DiseaseMammary Neoplasms, Human

NCOA3 BRIP1 FN1 SYNE1 ETS2 HPSE BMPR2 BRCA2 ITSN2 MED12 NOTCH1

3.59e-0552513711C1257931
DiseaseMammary Neoplasms

NCOA3 BRIP1 FN1 SYNE1 ETS2 HPSE BMPR2 BRCA2 ITSN2 MED12 NOTCH1

3.72e-0552713711C1458155
Diseaserespiratory system disease

PRR5L GATA3 PEX14 TBL1XR1 TLR1 RIC1

6.15e-051451376EFO_0000684
DiseaseBone marrow hypocellularity

BRIP1 FANCA BRCA2

7.59e-05181373C1855710
Diseaseurate measurement, bone density

ERBB4 PPFIBP1 SYNE1 ETS1 ETS2 PEX14 MARCHF7 FANCA ADGRE4P ROBO1 USH2A

1.55e-0461913711EFO_0003923, EFO_0004531
DiseaseFanconi Anemia

BRIP1 FANCA BRCA2

2.09e-04251373C0015625
Diseasetri-iodothyronine/thyroxine ratio measurement

ZMIZ1 KPNA3

2.12e-0451372EFO_0009779
Diseaseurate measurement

CDC42BPG SHLD2 ERBB4 ADGRV1 ZMIZ1 CUBN FRMD4B BMPR2 ASAP2 USP38 TMF1 RFT1 CLNK

2.83e-0489513713EFO_0004531
DiseaseVaricose veins

PPFIBP1 ETS1 ADGRV1 OR2B6 SLC12A2 ADGRF1

2.93e-041931376HP_0002619
Diseaserenal overload-type gout

SPATA31C2 SPATA31C1

3.17e-0461372EFO_0021525
DiseaseAdult only

BRCA2 MUTYH

3.17e-0461372C3842001
DiseaseMiller Dieker syndrome

BRIP1 FANCA BRCA2

3.27e-04291373C0265219
DiseaseBilateral Wilms Tumor

SIX1 BRCA2 SIX2

3.27e-04291373C2930471
Diseaseskin pigmentation measurement

KALRN FANCA HERC2 USH2A HYDIN

4.59e-041371375EFO_0007009
DiseaseAbnormality of radial ray

BRIP1 FANCA BRCA2

4.82e-04331373C4228778
Diseaseobsolete_red blood cell distribution width

ASNSD1 SP1 BRIP1 GATAD2A KALRN RBBP5 SLC6A19 SMG5 TBL1XR1 BMPR2 LIPA SLC12A2 PTPRH LPCAT3 MUC4 NOTCH1

5.32e-04134713716EFO_0005192
DiseaseAnimal Mammary Neoplasms

FN1 GATA3 GATM SLC12A2 ALCAM

5.40e-041421375C0024667
DiseaseMammary Carcinoma, Animal

FN1 GATA3 GATM SLC12A2 ALCAM

5.40e-041421375C1257925
Diseaseeosinophil cationic protein measurement

SPATA31C2 SPATA31C1

5.88e-0481372EFO_0010913
Diseasecervical cancer (is_marker_for)

MACC1 ERBB4 SPAG5

6.25e-04361373DOID:4362 (is_marker_for)
DiseaseNephroblastoma

SIX1 BRCA2 SIX2

6.25e-04361373C0027708
DiseaseProstatic Neoplasms

NCOA3 TBL1XR1 SLC12A2 BRCA2 ITSN2 TMF1 ROBO1 ALAD MUC4 MED12

6.26e-0461613710C0033578
DiseaseMalignant neoplasm of prostate

NCOA3 TBL1XR1 SLC12A2 BRCA2 ITSN2 TMF1 ROBO1 ALAD MUC4 MED12

6.26e-0461613710C0376358
Diseasemean corpuscular hemoglobin concentration

SP1 BRIP1 PRR5L GATAD2A KALRN TRIM54 SMG5 URB2 TBL1XR1 FRMD4B DMXL1 BMPR2 RPRD1A INTS13

6.46e-04110513714EFO_0004528
Diseaselongitudinal alcohol consumption measurement

SPATA31C2 SPATA31C1

7.54e-0491372EFO_0007645
DiseaseMammary Neoplasms, Experimental

FN1 GATA3 GATM SLC12A2 ALCAM

8.02e-041551375C0024668
DiseaseFanconi anemia (is_implicated_in)

FANCA BRCA2

9.40e-04101372DOID:13636 (is_implicated_in)
DiseaseMajor Depressive Disorder

KALRN NTRK3 HPSE ENPEP MED12 KPNA3

9.82e-042431376C1269683
DiseaseCarcinomatosis

FN1 GATA3 GATM SLC12A2 ALCAM

1.01e-031631375C0205699
DiseaseCarcinoma, Spindle-Cell

FN1 GATA3 GATM SLC12A2 ALCAM

1.01e-031631375C0205697
DiseaseUndifferentiated carcinoma

FN1 GATA3 GATM SLC12A2 ALCAM

1.01e-031631375C0205698
DiseaseAnaplastic carcinoma

FN1 GATA3 GATM SLC12A2 ALCAM

1.01e-031631375C0205696
DiseaseCarcinoma

FN1 GATA3 GATM SLC12A2 ALCAM

1.03e-031641375C0007097
DiseaseAdenocarcinoma of large intestine

ERBB4 TBL1XR1 DLC1 MUTYH

1.06e-03961374C1319315
Diseasemelanoma

ERBB4 DCBLD1 CUBN HPSE TMEM132B BRCA2

1.09e-032481376C0025202
Diseasehip geometry

KCNH8 ADGRV1 FRMD4B

1.13e-03441373EFO_0004685
Diseasecerebral cavernous malformation (implicated_via_orthology)

CDC42BPG RNF213

1.15e-03111372DOID:0060669 (implicated_via_orthology)
DiseaseCongenital Abnormality

SIX1 NOTCH1

1.15e-03111372C0000768
Diseasehearing impairment

ADGRV1 SIX1 FANCA USH2A

1.15e-03981374C1384666
Diseaseesophagus squamous cell carcinoma (is_implicated_in)

ERBB4 FANCA BRCA2

1.20e-03451373DOID:3748 (is_implicated_in)
DiseaseVitiligo

ZMIZ1 FANCA HERC2 CLNK

1.28e-031011374EFO_0004208
Diseasemyocardial infarction

BRIP1 FN1 KALRN DCBLD1 RSPH6A LIPA SLC15A1

1.28e-033501377EFO_0000612
DiseaseUnipolar Depression

KALRN NTRK3 HPSE ENPEP MED12 KPNA3

1.36e-032591376C0041696
Diseasehair colour measurement, hair morphology measurement

FANCA HERC2

1.37e-03121372EFO_0007821, EFO_0007822
DiseaseAlzheimer disease, dementia, family history of Alzheimer’s disease

KCNH8 DCBLD1 ROBO1

1.45e-03481373EFO_0009268, MONDO_0001627, MONDO_0004975
Diseasebipolar disorder

KPNA4 SYNE1 DCBLD1 ZMIZ1 HUWE1 ASAP2 DLC1 KCNU1 TARBP1

1.54e-035771379MONDO_0004985
Diseaseegg allergy measurement, parental genotype effect measurement

SPATA31C2 SPATA31C1

1.61e-03131372EFO_0005939, EFO_0007018
DiseaseColorectal Carcinoma

FN1 KALRN SYNE1 ZMIZ1 CUBN F5 DLC1 NLGN4X INTS13 MUTYH

1.67e-0370213710C0009402
Diseasenon-high density lipoprotein cholesterol measurement

SP1 FN1 GATA3 HEATR5A BMPR2 LIPA DLC1 BRCA2 ITSN2 HYDIN

1.87e-0371313710EFO_0005689
Diseaseskin melanoma (is_implicated_in)

FANCA BRCA2

1.88e-03141372DOID:8923 (is_implicated_in)
Diseasenephroblastoma (is_implicated_in)

SIX1 BRCA2

1.88e-03141372DOID:2154 (is_implicated_in)
Diseasetrimethylamine-N-oxide measurement

CUBN INTS13

1.88e-03141372EFO_0010541
DiseaseHereditary Breast and Ovarian Cancer Syndrome

BRIP1 BRCA2

1.88e-03141372C0677776
Diseaseleukemia

NCOA3 BRIP1 FANCA

2.15e-03551373C0023418
DiseaseNeoplasm of uncertain or unknown behavior of bladder

TBL1XR1 NOTCH1

2.16e-03151372C0496930
DiseaseBenign neoplasm of bladder

TBL1XR1 NOTCH1

2.16e-03151372C0154017
DiseaseCarcinoma in situ of bladder

TBL1XR1 NOTCH1

2.16e-03151372C0154091
Diseasegout

CDC42BPG SHLD2 OR13C3 FRMD4B CLNK

2.26e-031961375EFO_0004274
Diseasehippocampal atrophy

ETS1 TTC27 F5

2.27e-03561373EFO_0005039
Diseaseamygdala volume change measurement

SPATA31C2 SPATA31C1

2.46e-03161372EFO_0021490
Diseaseresponse to methotrexate

PRR5L COMMD9

2.46e-03161372GO_0031427
DiseasePolyposis, Adenomatous Intestinal

F5 MUTYH

2.46e-03161372C2713442
DiseaseFamilial Intestinal Polyposis

F5 MUTYH

2.46e-03161372C2713443
Diseasecolorectal cancer (is_implicated_in)

ERBB4 BRIP1 NTRK3 DLC1

2.48e-031211374DOID:9256 (is_implicated_in)
DiseaseMalignant neoplasm of skin

SP1 ERBB4 NOTCH1

2.63e-03591373C0007114
DiseaseSkin Neoplasms

SP1 ERBB4 NOTCH1

2.63e-03591373C0037286
Diseasepursuit maintenance gain measurement

NLGN4Y SPATA31C2 SPATA31C1 ENPEP

2.64e-031231374EFO_0008433
DiseaseAdenomatous Polyposis Coli

F5 MUTYH

2.78e-03171372C0032580
Diseaseceliac disease

ETS1 ZMIZ1 FRMD4B HYDIN

2.87e-031261374EFO_0001060
Diseasebreast carcinoma

ERBB4 GATAD2A PEX14 ZMIZ1 UBE2U KCNU1 SLC12A2 BRCA2 TLR1 ALCAM CD180 PCM1

2.89e-03101913712EFO_0000305
Diseaseacute kidney failure (biomarker_via_orthology)

FN1 GATM ALAD

2.89e-03611373DOID:3021 (biomarker_via_orthology)
DiseaseCarcinoma of bladder

TBL1XR1 NOTCH1

3.12e-03181372C0699885
Diseasebone mineral content measurement

ADGRV1 ALCAM HERC2 CLNK

3.22e-031301374EFO_0007621
Diseaseskin sensitivity to sun

FANCA HERC2

3.47e-03191372EFO_0004795
Diseaseacute lymphoblastic leukemia, response to antineoplastic agent

NCOA3 GATA3

3.47e-03191372EFO_0000220, GO_0097327
DiseaseMYELODYSPLASTIC SYNDROME

BRIP1 FANCA BRCA2

3.78e-03671373C3463824
Diseasediet measurement, body mass index

ATP13A5 TBL1XR1

3.85e-03201372EFO_0004340, EFO_0008111
Diseaseserum homoarginine measurement

GATM SLC15A1

3.85e-03201372EFO_0005421
DiseaseAdenocarcinoma of prostate

FANCA BRCA2

3.85e-03201372C0007112
Diseaselifestyle measurement, anxiety disorder measurement

TRHDE TTC27 USH2A SIX2

3.88e-031371374EFO_0007795, EFO_0010724
Diseaseskin pigmentation

RPRD1B FANCA HERC2

4.10e-03691373EFO_0003784
Diseasehaptoglobin measurement

DLC1 HYDIN

4.24e-03211372EFO_0004640
DiseaseBREAST CANCER

BRIP1 BRCA2

4.24e-03211372114480
DiseaseMalignant Glioma

NTRK3 DMXL1 BRCA2

4.27e-03701373C0555198
Diseasemixed gliomas

NTRK3 DMXL1 BRCA2

4.27e-03701373C0259783
DiseaseAbnormality of refraction

BRIP1 PEX14 RGS3 CHRNG PTPN5 DLC1 ROBO1 MOCOS KPNA2

4.28e-036731379HP_0000539
DiseaseMalignant neoplasm of urinary bladder

TBL1XR1 FANCA BRCA2 NOTCH1

4.30e-031411374C0005684
Diseaseestrogen-receptor negative breast cancer

PEX14 KCNU1 BRCA2

4.44e-03711373EFO_1000650

Protein segments in the cluster

PeptideGeneStartEntry
QQASTLISDWISSNR

TRHDE

831

Q9UKU6
TWTQAGQGQLRQVLS

URB2

216

Q14146
TINWTTLFSTINQRI

ERBB4

471

Q15303
SNFSTNVSLERNWTG

ATP13A5

1016

Q4VNC0
NSTRLWNSQSSIDQK

ERVK-18

396

O42043
KNSTRLWNSQSSIDQ

ERVK-19

506

O71037
KNSTRLWNSQSSIDQ

ERVK-8

506

Q902F8
NSTRLWNSQSSIDQK

ERVK-9

506

Q9UKH3
GSQTSFQWTQEQPLS

CCDC116

226

Q8IYX3
IASSNNLLNKNAWGS

CRYBG3

326

Q68DQ2
SIADNILNSASVTNW

ADGRF1

376

Q5T601
QSRLQNGSSGWSITT

CHRNG

371

P07510
NNSQGTTQSNVDIWV

ADGRE4P

106

Q86SQ3
HGNVSANWVLTRNST

ADGRV1

426

Q8WXG9
NSGTLGNVTVQWVAT

ADGRV1

2261

Q8WXG9
GSTSSVGQAWLNQVL

DOP1A

971

Q5JWR5
GRWSQVTLTQVLQTQ

DNHD1

4286

Q96M86
QSLTSIPAFSQRNWQ

RAD54L2

996

Q9Y4B4
GLQNSTTQSLWLGTF

CD180

241

Q99467
LTGSSYLQLWSNTNL

DMXL1

126

Q9Y485
SQISRQLNQSQVAWT

ARNT2

561

Q9HBZ2
LTNSNRLTTTRNAVW

KPNA5

221

O15131
WTVSNITAGNRAQIQ

KPNA5

361

O15131
LSGGTQRDWSQTLNL

RFT1

71

Q96AA3
TVWNRASQSRQSGLI

RGS3

221

P49796
DAGISNIQRSQSWLS

RIC1

1161

Q4ADV7
NIQRSQSWLSNIGPT

RIC1

1166

Q4ADV7
NLSQTQLATIWTLAD

ITSN2

276

Q9NZM3
IWSQNATNLVSSLLT

PTPN5

111

P54829
VSLLSLWSNRINTAN

INTS13

651

Q9NVM9
VSSLSRQVTQLQGQW

CDC42BPG

561

Q6DT37
RDWSNGAVLQASSQL

GATAD2A

516

Q86YP4
AQWTLGSNTYQAILS

MUC4

4461

Q99102
AWALTNIASGTSQQT

KPNA6

146

O60684
TGFSNSVWLSTLTLQ

OR2B6

151

P58173
AWALTNIASGTSAQT

KPNA3

136

O00505
NLTQSRSTTWKLNNL

nan

241

O00370
STSLNGQCEWLSRLQ

NOTCH1

2301

P46531
KQIVSSQNGLSAWTS

SPACA5

116

Q96QH8
LTQGTGSWAQSALTQ

IGLV2-33

11

A0A075B6J2
LSWSDTAQVTNQRVQ

ITIH2

791

P19823
SNRLTTLSWQLFQTL

NTRK3

136

Q16288
WVQRTFQSTQAATAS

GATM

31

P50440
WIASGQTLLQASQQD

PPFIBP1

671

Q86W92
LRAWQTATTTLNASN

ALAD

16

P13716
TVQSAAQAVLQSGWS

HERC2

881

O95714
WLQSSIFSGGLQTSQ

HERC2

1336

O95714
NTQINNSWGSEERSL

LGALS9C

281

Q6DKI2
NVGKVQTASSANTLW

ASAP2

791

O43150
QTASSANTLWKTNSV

ASAP2

796

O43150
WWLTGSNLTLSVNNS

ERVMER34-1

281

Q9H9K5
NTQINNSWGSEERSL

LGALS9B

281

Q3B8N2
LTQDTGSWAQSALTQ

IGLV2-23

11

P01705
QSWSSQSSFNSLQRV

ETS1

266

P14921
SVNSGTWIASNSELT

PCM1

1446

Q15154
SSWDSVIQNKTGRNQ

EVI2A

41

P22794
SLLQSWNSQSSLLDV

ETS2

291

P15036
ISNRQSFWQSAGETN

FAM214A

346

Q32MH5
GSQIWQQSVASTLDT

KALRN

2611

O60229
LQNVQTIPSWLSGTS

DNAH12

361

Q6ZR08
WDAINRLSNTGSGLQ

PRCP

241

P42785
TGTIASFNINTNAWV

LPCAT3

331

Q6P1A2
QQNGTASSRKTLWNQ

GPKOW

306

Q92917
LTQGTGSWAQSALTQ

IGLV2-18

11

A0A075B6J9
NFWLVTARSQSAINT

MED12

101

Q93074
LTGSRVWNNSSTVNA

MOCOS

536

Q96EN8
AWNQSRTNSIISSQI

KCNU1

1106

A8MYU2
LNNASSLFEQWLNGT

ENPEP

761

Q07075
ITSWVSGSINSLVQT

OR2F2

146

O95006
SASWLSGLTNSVAQT

OR2I1P

146

Q8NGU4
SVNQWGSQLGLSVLS

HUWE1

921

Q7Z6Z7
SAAVAIWQTLQQTTG

IP6K3

101

Q96PC2
IWQTLQQTTGSNGSD

IP6K3

106

Q96PC2
KNSTRLWNSQSSIDQ

ERVK-7

1266

P63135
LLRTADLQWNSSNAQ

HPSE

191

Q9Y251
ASISSGVVSIWAQNQ

RBBP5

311

Q15291
ITQLGLQNSTITFWN

CD200

96

P41217
ARQALQLSSSSAWNS

PRR5L

41

Q6MZQ0
QLSSSSAWNSVQTAV

PRR5L

46

Q6MZQ0
QTKRVSWSSFNSLGQ

BRIP1

996

Q9BX63
AWALTNIASGTSEQT

KPNA2

141

P52292
AIIQSGTALSSWAVN

NLGN4Y

276

Q8NFZ3
VSTWRTEAQANQISL

COMMD9

106

Q9P000
WTLSNPNQGNSSISI

CUBN

2601

O60494
QTTTTTLWRRNANGD

GATA3

321

P23771
VSSTNASGNWRTQLT

FRMD4B

951

Q9Y2L6
TQTILLSNRTNQTWN

HYDIN

4646

Q4G0P3
QNSRLSAQRTQAGWL

HEATR5A

541

Q86XA9
WNSSITLTSQAGAVF

DNASE2

211

O00115
NLIDNGSWPATTTQN

BRCA2

556

P51587
NSTRLWNSQSSIDQK

ERVK-24

396

P61566
KNSTRLWNSQSSIDQ

ERVK-25

506

P61570
KNSTRLWNSQSSIDQ

ERVK-6

506

Q69384
NSTRLWNSQSSIDQK

ERVK-7

396

P61567
STGQEALSQTTISWA

FN1

2201

P02751
LQALTSGWSVAASLQ

FANCA

1056

O15360
QQSDTWSLSKTSLVN

CCDC191

921

Q8NCU4
TSSELNSGQNFLTQW

CENPJ

6

Q9HC77
TSSQLSTPLQQWRQG

IGHD

66

P01880
WTILLVSTAAASQNQ

BMPR2

16

Q13873
SNNFNLNITWSVGST

ATRNL1

1151

Q5VV63
NSTRLWNSQSSIDQK

ERVK-21

506

P61565
NTISQSPGWAQTQLA

MACC1

196

Q6ZN28
NVGNGLNTLSDSSWR

MARCHF7

106

Q9H992
LSSVGTQTSGLANQW

ASNSD1

156

Q9NWL6
SRIQGGWTTISQLTQ

IQCB1

71

Q15051
WNQQDGTLSLSQRQL

EMC10

76

Q5UCC4
QIRASSSWQSVNESG

DCBLD1

266

Q8N8Z6
NNWTGQLSYRTLATV

C4orf54

36

D6RIA3
LFDQQGSRWTLQATT

SLC15A1

296

P46059
ASNWGLITNIVNSIV

SLC38A10

6

Q9HBR0
QWTITGSGSVINQTE

ALCAM

446

Q13740
AIIQSGTALSSWAVN

NLGN4X

276

Q8N0W4
LTQGTGSWAQSALTQ

IGLV2-11

11

P01706
STSWVIGFANSLLQT

OR2B8P

146

P59922
SVSWLSGGINSAVQT

OR13C3

176

Q8NGS6
LTQGTGSWAQSALTQ

IGLV2-14

11

P01704
VLITGSLNWTTQAIQ

PLD6

166

Q8N2A8
GWSQRGSLSQQENLL

RSPH6A

56

Q9H0K4
GTSWVSNVFTNITQL

USH2A

351

O75445
RGQVQSSSAINLSWS

USH2A

1061

O75445
GSDSVTLTWTTLSNQ

USH2A

1161

O75445
LNISTSISDSGSIQW

SLC6A19

181

Q695T7
LSNSQQSVQTLSLWL

RPRD1B

16

Q9NQG5
VQQTVSLTSTLQQDW

SPAG5

631

Q96R06
SARSWATAIQAQVNT

SNTA1

256

Q13424
LGGSNSQVSALSWSQ

SPATA31C2

276

B4DYI2
AQSSQSLWNRLSVLL

SMG5

676

Q9UPR3
LAQARTTWTQQRQSS

SYNE1

6216

Q8NF91
NSSDLAGAQQITWQV

TMEM132B

381

Q14DG7
TAVNNWLISPQNASR

F5

966

P12259
LTQGTGSWAQSALTQ

IGLV2-8

11

P01709
STVNGVSWTNETQRQ

NCOA3

176

Q9Y6Q9
QWIGETVLQSTFSSQ

SHLD2

516

Q86V20
NTQSQSWNVETLRSS

SHPK

206

Q9UHJ6
ALQDITLSQQTPSTW

SDC1

51

P18827
TGLTTTQVSNWFKNR

SIX1

161

Q15475
LATTVWVSRNPSSQN

SPATA31E1

451

Q6ZUB1
SSTLVSQQLWGLAQQ

MUTYH

251

Q9UIF7
NSQVSALSWSQETTK

SPATA31C1

286

P0DKV0
TATQLSQGANGWQII

SP1

96

P08047
ATTSTNWILESQNIN

PEX14

196

O75381
LPIIQSNQVSSNSWG

DLC1

151

Q96QB1
WNLSENSTSGSTQLV

TBL1XR1

196

Q9BZK7
LSNLTLNNIETTWNS

TLR1

246

Q15399
TSISIGQPTWNTQTR

CLNK

116

Q7Z7G1
KQGSSSSQLQSWTVQ

CIPC

101

Q9C0C6
STFSILQTWDTINLN

RNF213

536

Q63HN8
QASNPLWQSRGSTTV

TRIM54

56

Q9BYV2
SIQSSVQQGLQTQDW

TEX22

36

C9J3V5
ENLQATLGSQTSSWE

TMF1

776

P82094
QATSWALTSQLQQLR

TEX13D

101

A0A0J9YY54
QGLQAAGTDSSQTIW

UBTFL1

341

P0CB47
LSNSQQSVQTLSLWL

RPRD1A

16

Q96P16
VNWGSSTQALTYLNA

SLC12A2

756

P55011
QATSWALTSQLQQLR

TEX13C

101

A0A0J9YWL9
AGNTQTTWTTLQLAG

USF3

426

Q68DE3
TTWTTLQLAGNTIQP

USF3

431

Q68DE3
DLISWTNTLNTNTSE

UBE2U

306

Q5VVX9
TVTLSWQPNLNSGAT

ROBO1

576

Q9Y6N7
ILNQSAWTSQSNSLA

USP38

416

Q8NB14
TGLTTTQVSNWFKNR

SIX2

161

Q9NPC8
IISSLSNTQLIFWAN

TARBP1

976

Q13395
SWIVSASNVSQGSLS

TARBP1

1046

Q13395
NWTSLKNILSGLNAS

TEX15

16

Q9BXT5
LGVSSLQLFVQSNWT

TTC27

96

Q6P3X3
NAVTSLSKQDWTNST

PTPRH

476

Q9HD43
SRAIWAALQTQTSNA

UGGT1

811

Q9NYU2
VVTTVWGVTNTSQSQ

ZMIZ1

166

Q9ULJ6
NTNWPASVQVSVNAT

ZMIZ1

621

Q9ULJ6
AWALTNIASGTSEQT

KPNA4

136

O00629
WELLQQVNTSTGTNN

KRT77

196

Q7Z794
QAQLCSSNITSDIWS

KCNH8

946

Q96L42
DSSNWVTNLANSSLG

LIPA

91

P38571
SGKSLTQSLWLNNNV

LRRC51

46

Q96E66
RLSNWNISLESQTLQ

LRIG2

86

O94898