Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontranscription coregulator activity

BCL9L NCOA3 TCF4 NCOA6 HDAC4 HIPK1 EID2B BCL9 RUVBL2 ZIC3 ARID1B KMT2D TLE3 TOX3 EID1 MED23

2.83e-0656214316GO:0003712
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

NCOA3 TCF4 TBX21 ASCL5 ATF6B ZEB2 MEIS1 MEIS2 ZIC3 KMT2D TP63 BARHL2 ZNF91 ONECUT3 FOXF1

1.22e-0556014315GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

NCOA3 TCF4 TBX21 ASCL5 ATF6B ZEB2 MEIS1 MEIS2 ZIC3 KMT2D TP63 BARHL2 ZNF91 ONECUT3 FOXF1

1.38e-0556614315GO:0001216
GeneOntologyMolecularFunctionmolecular adaptor activity

BCL9L NCOA3 TCF4 NCOA6 HDAC4 OFD1 HIPK1 ITSN1 EID2B AMBRA1 BCL9 RUVBL2 ST13 KCTD17 ZIC3 ARID1B KMT2D TLE3 ITSN2 TOX3 EID1 ZNF91 MED23

9.51e-05135614323GO:0060090
GeneOntologyMolecularFunctionprofilin binding

PCLO DBN1 ENAH

9.76e-05131433GO:0005522
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

BCL9L NCOA3 TCF4 NCOA6 HDAC4 HIPK1 EID2B AMBRA1 BCL9 RUVBL2 ST13 KCTD17 ZIC3 ARID1B KMT2D TLE3 TOX3 EID1 ZNF91 MED23

2.30e-04116014320GO:0030674
GeneOntologyMolecularFunctiontranscription coactivator activity

BCL9L NCOA3 NCOA6 BCL9 ZIC3 ARID1B KMT2D TOX3 MED23

3.42e-043031439GO:0003713
GeneOntologyMolecularFunctionhistone H3K4 methyltransferase activity

KMT2B KMT2D SETBP1

3.75e-04201433GO:0042800
GeneOntologyMolecularFunctiontRNA (cytidine-5-)-methyltransferase activity

NSUN4 NSUN6

5.02e-0451432GO:0016428
GeneOntologyMolecularFunctiondATP binding

ST13 ST13P5

5.02e-0451432GO:0032564
GeneOntologyMolecularFunctionadenyl deoxyribonucleotide binding

ST13 ST13P5

7.50e-0461432GO:0032558
GeneOntologyMolecularFunctionpurine deoxyribonucleotide binding

ST13 ST13P5

1.04e-0371432GO:0032554
GeneOntologyMolecularFunctiontranscription corepressor activity

TCF4 HDAC4 HIPK1 EID2B RUVBL2 TLE3 EID1

1.33e-032291437GO:0003714
GeneOntologyMolecularFunctionhistone H3K4 monomethyltransferase activity

KMT2B KMT2D

1.39e-0381432GO:0140945
GeneOntologyMolecularFunctionS-adenosylmethionine-dependent methyltransferase activity

NSUN4 KMT2B NSUN6 KMT2D SETBP1 PRMT7

1.51e-031721436GO:0008757
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

NCOA3 TCF4 HDAC4 TBX21 ASCL5 RUVBL2 ATF6B ZEB2 MEIS1 MEIS2 HSF5 ZIC3 STK16 BBX TP63 BARHL2 ZFHX3 ZNF91 ONECUT3 ZNF98 FOXF1

1.67e-03145914321GO:0000977
GeneOntologyMolecularFunctionhistone methyltransferase activity

KMT2B KMT2D SETBP1 PRMT7

1.69e-03711434GO:0042054
GeneOntologyMolecularFunctionbeta-catenin binding

BCL9L TCF4 AMER1 BCL9 RUVBL2

1.73e-031201435GO:0008013
GeneOntologyMolecularFunctiondeoxyribonucleotide binding

ST13 ST13P5

1.77e-0391432GO:0032552
GeneOntologyMolecularFunctiontRNA (cytidine) methyltransferase activity

NSUN4 NSUN6

2.21e-03101432GO:0016427
GeneOntologyMolecularFunctionhistone H3K4 trimethyltransferase activity

KMT2B KMT2D

2.21e-03101432GO:0140999
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

BCL9L NCOA3 TCF4 NCOA6 HDAC4 TBX21 ASCL5 BCL9 RUVBL2 ATF6B ZEB2 MEIS1 MEIS2 ZIC3 STK16 ZNF462 KMT2D CSF3 TP63 BARHL2 TOX3 ZFHX3 CHD6 ZNF91 ONECUT3 MED23 FOXF1

8.23e-07139014227GO:0045944
GeneOntologyCellularComponentbeta-catenin-TCF complex

BCL9L TCF4 BCL9 TLE3

1.43e-06131434GO:1990907
GeneOntologyCellularComponenttranscription regulator complex

BCL9L NCOA3 TCF4 NCOA6 HDAC4 ASCL5 BCL9 ATF6B MEIS1 GTF3C2 TLE3 ZFHX3 ONECUT3 MED23 FOXF1

1.49e-0559614315GO:0005667
GeneOntologyCellularComponentpostsynaptic actin cytoskeleton

ITSN1 DBN1 KPTN

2.80e-04191433GO:0098871
HumanPhenoShort fourth metatarsal

TCF4 HDAC4 CDC42BPB ITPR1 PRMT7

4.43e-0716545HP:0004689
HumanPhenoAbnormality of the fourth metatarsal bone

TCF4 HDAC4 CDC42BPB ITPR1 PRMT7

4.43e-0716545HP:0040035
HumanPhenoAbnormality of dental eruption

TCF4 MIA3 AMER1 HDAC4 TRIO ZEB2 SEC24D ARID1B KMT2D TP63 SETBP1 CHD6

5.34e-062405412HP:0006292
HumanPhenoAnkyloglossia

COL7A1 OFD1 CDC42BPB KMT2D SETBP1

1.09e-0529545HP:0010296
HumanPhenoDelayed speech and language development

POMT2 CACNA1E TCF4 AMPD2 AMER1 KMT2B HDAC4 OFD1 TRIO WDR81 ZEB2 MEIS2 OPHN1 ITPR1 KPTN ZNF462 ACSL4 ARID1B NSUN6 KMT2D TP63 SETBP1 TRAPPC10 MED23 PRMT7 MN1

1.86e-0511235426HP:0000750
HumanPhenoAbnormal nasal tip morphology

TCF4 KMT2B HDAC4 OFD1 TRIO CDC42BPB ZEB2 KPTN ZNF462 ARID1B KMT2D TP63 SETBP1 PRMT7

3.19e-053865414HP:0000436
HumanPhenoDilatation of the renal pelvis

MIA3 HDAC4 OFD1 LAMB3 CDC42BPB ZEB2 ZIC3 ARID1B KMT2D TP63 SETBP1 FOXF1

3.66e-052905412HP:0010946
HumanPhenoAbnormality of the palpebral fissures

TCF4 AMPD2 HDAC4 OFD1 TRIO PCLO CDC42BPB ZEB2 MEIS2 ITPR1 KPTN ZNF462 ACSL4 SEC24D ARID1B KMT2D TP63 SETBP1 TRAPPC10 HSD17B4 PRMT7 MN1

3.78e-058805422HP:0008050
HumanPhenoLanguage impairment

POMT2 CACNA1E TCF4 AMPD2 AMER1 KMT2B HDAC4 OFD1 TRIO WDR81 ZEB2 MEIS2 OPHN1 ITPR1 KPTN ZNF462 ACSL4 ARID1B NSUN6 KMT2D TP63 SETBP1 TRAPPC10 MED23 PRMT7 MN1

4.52e-0511785426HP:0002463
HumanPhenoAbnormal renal pelvis morphology

MIA3 HDAC4 OFD1 LAMB3 CDC42BPB ZEB2 ZIC3 ARID1B KMT2D TP63 SETBP1 FOXF1

5.11e-053005412HP:0010944
HumanPhenoAplasia/Hypoplasia of metatarsal bones

TCF4 HDAC4 CDC42BPB ITPR1 TP63 PRMT7

5.96e-0566546HP:0001964
HumanPhenoHydronephrosis

MIA3 HDAC4 OFD1 LAMB3 ZEB2 ZIC3 ARID1B KMT2D TP63 SETBP1 FOXF1

7.68e-052645411HP:0000126
HumanPhenoIntellectual disability, severe

POMT2 TCF4 KMT2B OFD1 WDR81 ZEB2 OPHN1 ITPR1 ACSL4 ARID1B SETBP1 TRAPPC10 PRMT7

9.33e-053715413HP:0010864
HumanPhenoRetrognathia

MIA3 AMER1 KMT2B OFD1 TRIO KPTN SEC24D ARID1B KMT2D SETBP1 HSD17B4 PRMT7 FOXF1

1.04e-043755413HP:0000278
HumanPhenoBilirubinuria

SLCO1B3 SLCO1B1

1.10e-042542HP:0031811
HumanPhenoFrontal bossing

AMER1 KMT2B HDAC4 OFD1 TRIO CDC42BPB ZEB2 MEIS2 OPHN1 ITPR1 KPTN SEC24D ARID1B KMT2D TP63 SETBP1 CHD6 HSD17B4 PRMT7

1.12e-047385419HP:0002007
HumanPhenoSlanting of the palpebral fissure

TCF4 AMPD2 HDAC4 OFD1 TRIO CDC42BPB ZEB2 MEIS2 ITPR1 KPTN ZNF462 ACSL4 SEC24D ARID1B KMT2D SETBP1 TRAPPC10 HSD17B4 MN1

1.14e-047395419HP:0200006
HumanPhenoDelayed eruption of teeth

TCF4 MIA3 AMER1 HDAC4 TRIO ZEB2 SEC24D ARID1B SETBP1

1.17e-04185549HP:0000684
HumanPhenoAbnormal shape of the frontal region

AMER1 KMT2B HDAC4 OFD1 TRIO CDC42BPB ZEB2 MEIS2 OPHN1 ITPR1 KPTN SEC24D ARID1B KMT2D TP63 SETBP1 CHD6 HSD17B4 PRMT7

1.19e-047415419HP:0011218
HumanPhenoAbnormal frontal bone morphology

AMER1 KMT2B HDAC4 OFD1 TRIO CDC42BPB ZEB2 MEIS2 OPHN1 ITPR1 KPTN SEC24D ARID1B KMT2D TP63 SETBP1 CHD6 HSD17B4 PRMT7

1.21e-047425419HP:0430000
HumanPhenoAbnormal eyelid morphology

TCF4 AMPD2 AMER1 KMT2B HDAC4 OFD1 TRIO PCLO CDC42BPB ZEB2 MEIS2 KCTD17 ITPR1 KPTN ZNF462 ACSL4 SEC24D ZNF469 ARID1B KMT2D TP63 SETBP1 TRAPPC10 DSG4 CHD6 HSD17B4 PRMT7 MN1

1.33e-0414085428HP:0000492
HumanPhenoAbnormality of the dentition

TCF4 COL7A1 MIA3 AMER1 HDAC4 OFD1 TRIO LAMB3 CDC42BPB ZEB2 MEIS2 ITPR1 ACSL4 SEC24D ZNF469 ARID1B KMT2D TP63 SETBP1 AGXT DSG4 CHD6 PRMT7

1.43e-0410305423HP:0000164
HumanPhenoDeviation of the hand or of fingers of the hand

TCF4 MIA3 AMER1 KMT2B HDAC4 OFD1 TRIO ZEB2 ZIC3 KPTN ZNF462 ARID1B KMT2D TP63 SETBP1 CHD6

1.55e-045645416HP:0009484
HumanPhenoSparse eyebrow

TCF4 HDAC4 CDC42BPB MEIS2 KMT2D TP63 DSG4 CHD6

1.62e-04151548HP:0045075
HumanPhenoAbnormal midface morphology

TCF4 AMPD2 KMT2B HDAC4 OFD1 TRIO PCLO CDC42BPB ZNF462 ACSL4 SEC24D ARID1B KMT2D TP63 SETBP1 CHD6 PRMT7 MN1

2.01e-047045418HP:0000309
HumanPhenoAbnormality of the forehead

POMT2 TCF4 AMPD2 AMER1 KMT2B HDAC4 OFD1 TRIO CDC42BPB ZEB2 MEIS2 OPHN1 ITPR1 KPTN ZNF462 SEC24D ARID1B KMT2D TP63 SETBP1 TRAPPC10 CHD6 HSD17B4 PRMT7 MN1

2.16e-0412085425HP:0000290
HumanPhenoAbnormal palm morphology

TCF4 COL7A1 KMT2B HDAC4 TRIO DSG1 WDR81 LAMB3 CDC42BPB ZNF462 ZNF469 ARID1B KMT2D TP63 SETBP1

2.26e-045215415HP:0100871
HumanPhenoAplasia/Hypoplasia involving bones of the feet

TCF4 MIA3 HDAC4 OFD1 WDR81 CDC42BPB ITPR1 ARID1B TP63 CHD6 PRMT7

2.27e-042985411HP:0006494
HumanPhenoDeficiency of speech development

POMT2 CACNA1E TCF4 AMPD2 HDAC4 OFD1 TRIO ZEB2 OPHN1 ARID1B TP63 SETBP1 TRAPPC10 MED23

2.32e-044635414HP:0002116
HumanPhenoSupernumerary tooth

AMER1 OFD1 ACSL4 KMT2D TP63 CHD6

2.46e-0485546HP:0011069
HumanPhenoHighly arched eyebrow

HDAC4 OFD1 TRIO CDC42BPB ZEB2 MEIS2 ZNF462 KMT2D MN1

2.65e-04206549HP:0002553
HumanPhenoCongenital malformation of the great arteries

AMER1 KMT2B HDAC4 OFD1 TRIO CDC42BPB ZEB2 ZIC3 ITPR1 ZNF462 ACSL4 ARID1B KMT2D TP63 FOXF1

2.67e-045295415HP:0011603
HumanPhenoDelayed ability to walk

AMPD2 HDAC4 TRIO WDR81 ZEB2 OPHN1 ITPR1 KPTN ARID1B TRAPPC10 PRMT7

2.70e-043045411HP:0031936
HumanPhenoAbnormal skin morphology of the palm

TCF4 COL7A1 HDAC4 TRIO DSG1 LAMB3 CDC42BPB ZNF462 ZNF469 ARID1B KMT2D TP63 SETBP1

2.76e-044135413HP:0040211
HumanPhenoLip pit

OFD1 KMT2D TP63

2.99e-0413543HP:0100267
HumanPhenoAbnormal hand morphology

TCF4 COL7A1 MIA3 AMER1 KMT2B HDAC4 OFD1 TRIO WDR81 LAMB3 CDC42BPB ZEB2 MEIS2 ZIC3 KPTN ZNF462 ARID1B KMT2D TP63 SETBP1 CHD6 HSD17B4 PRMT7

3.10e-0410825423HP:0005922
HumanPhenoDeviation of finger

TCF4 MIA3 AMER1 KMT2B HDAC4 OFD1 TRIO ZIC3 KPTN ZNF462 ARID1B KMT2D TP63 SETBP1 CHD6

3.15e-045375415HP:0004097
HumanPhenoThin corpus callosum

POMT2 CACNA1E TCF4 AMPD2 AMER1 HDAC4 OFD1 PCLO WDR81 CDC42BPB ZEB2 ITPR1 ZNF462 ARID1B KMT2D SETBP1 TRAPPC10 HSD17B4 MED23 PRMT7

3.25e-048685420HP:0033725
HumanPhenoIntellectual disability, mild

POMT2 MIA3 AMER1 KMT2B TRIO ITPR1 ZNF462 ARID1B KMT2D SETBP1 HSD17B4 PRMT7

3.33e-043655412HP:0001256
HumanPhenoMotor delay

POMT2 TCF4 AMPD2 KMT2B HDAC4 OFD1 TRIO WDR81 ZEB2 OPHN1 ITPR1 KPTN ZNF462 SEC24D ARID1B NSUN6 KMT2D SETBP1 TRAPPC10 HSD17B4 PRMT7 MN1

3.58e-0410185422HP:0001270
HumanPhenoShort metatarsal

TCF4 HDAC4 CDC42BPB ITPR1 PRMT7

4.54e-0462545HP:0010743
HumanPhenoAbsent speech

POMT2 CACNA1E TCF4 AMPD2 HDAC4 OFD1 TRIO ZEB2 OPHN1 ARID1B SETBP1 TRAPPC10 MED23

4.69e-044365413HP:0001344
HumanPhenoPatent ductus arteriosus

AMER1 KMT2B HDAC4 TRIO CDC42BPB ZEB2 ZIC3 ACSL4 ARID1B KMT2D TP63 FOXF1

5.06e-043825412HP:0001643
HumanPhenoSparse hair

KMT2B HDAC4 OFD1 DSG1 LAMB3 CDC42BPB ARID1B KMT2D TP63 DSG4 CHD6 PRMT7

5.19e-043835412HP:0008070
HumanPhenoMulticystic kidney dysplasia

AMER1 HDAC4 OFD1 LAMB3 ZEB2 KMT2D

5.33e-0498546HP:0000003
HumanPhenoThick vermilion border

TCF4 AMER1 HDAC4 OFD1 TRIO ZEB2 ACSL4 ARID1B KMT2D SETBP1

5.77e-042795410HP:0012471
HumanPhenoAbnormal 5th finger morphology

MIA3 AMER1 KMT2B HDAC4 OFD1 TRIO MEIS2 KPTN ZNF462 ARID1B KMT2D TP63 SETBP1 CHD6

6.18e-045095414HP:0004207
HumanPhenoAbnormality of the curvature of the cornea

TCF4 KMT2B HDAC4 OFD1 ARHGEF18 ZEB2 ITPR1 ZNF469 ARID1B SETBP1 PRMT7

6.39e-043365411HP:0100691
HumanPhenoFinger clinodactyly

TCF4 MIA3 AMER1 KMT2B HDAC4 OFD1 TRIO KPTN ZNF462 ARID1B KMT2D TP63 CHD6

6.64e-044525413HP:0040019
HumanPhenoMilia

COL7A1 OFD1 LAMB3

6.89e-0417543HP:0001056
HumanPhenoUnderdeveloped nasal alae

HDAC4 OFD1 TRIO KMT2D TP63 CHD6

7.31e-04104546HP:0000430
HumanPhenoAbnormality of hair density

KMT2B HDAC4 OFD1 DSG1 LAMB3 CDC42BPB ARID1B KMT2D TP63 DSG4 CHD6 PRMT7

7.34e-043985412HP:0011357
HumanPhenoAbnormal oral frenulum morphology

COL7A1 OFD1 CDC42BPB KMT2D SETBP1

7.96e-0470545HP:0000190
HumanPhenoAbnormality of corneal size

POMT2 TCF4 KMT2B HDAC4 OFD1 ARHGEF18 ZEB2 ITPR1 ZNF469 ARID1B KMT2D SETBP1 PRMT7

8.01e-044615413HP:0001120
HumanPhenoVentriculomegaly

POMT2 TCF4 AMPD2 HDAC4 OFD1 WDR81 CDC42BPB ZEB2 OPHN1 ITPR1 KPTN ZNF462 ARID1B KMT2D SETBP1 TRAPPC10 HSD17B4 FOXF1

8.52e-047905418HP:0002119
HumanPhenoPruritus

TCF4 COL7A1 MIA3 SLCO1B3 SLCO1B1 ZEB2 DSG4

8.89e-04149547HP:0000989
HumanPhenoAbnormal corpus callosum morphology

POMT2 CACNA1E TCF4 AMPD2 AMER1 HDAC4 OFD1 PCLO WDR81 CDC42BPB ZEB2 ITPR1 ZNF462 ARID1B KMT2D SETBP1 TRAPPC10 HSD17B4 MED23 PRMT7

9.10e-049375420HP:0001273
HumanPhenoAbnormal fetal gastrointestinal system morphology

ZIC3 KMT2D HSD17B4

9.68e-0419543HP:0034207
HumanPhenoAbnormality of globe location or size

POMT2 TCF4 AMER1 KMT2B HDAC4 OFD1 TRIO PCLO CDC42BPB ZEB2 MEIS2 OPHN1 ZIC3 KPTN ZNF462 SEC24D ARID1B KMT2D SETBP1 CHD6 HSD17B4 PRMT7 MN1 FOXF1

9.81e-0412465424HP:0000489
DomainBCL9

BCL9L BCL9

5.58e-0521402PF11502
DomainBcl-9

BCL9L BCL9

5.58e-0521402IPR015668
DomainBCL9_beta-catenin-bd_dom

BCL9L BCL9

5.58e-0521402IPR024670
DomainPH_13

ITSN1 ITSN2

5.58e-0521402PF16652
DomainEH

SYNRG ITSN1 ITSN2

6.51e-05111403PS50031
DomainEH

SYNRG ITSN1 ITSN2

6.51e-05111403SM00027
DomainEH_dom

SYNRG ITSN1 ITSN2

6.51e-05111403IPR000261
DomainRhoGEF

TRIO ITSN1 ARHGEF18 ITSN2 VAV2

1.57e-04681405SM00325
DomainEID

EID2B EID1

1.67e-0431402IPR033258
DomainRhoGEF

TRIO ITSN1 ARHGEF18 ITSN2 VAV2

1.80e-04701405PF00621
DomainDH_2

TRIO ITSN1 ARHGEF18 ITSN2 VAV2

1.80e-04701405PS50010
Domain-

TRIO ITSN1 ARHGEF18 ITSN2 VAV2

1.93e-047114051.20.900.10
DomainDH-domain

TRIO ITSN1 ARHGEF18 ITSN2 VAV2

1.93e-04711405IPR000219
DomainDesmoglein

DSG1 DSG4

3.31e-0441402IPR009123
DomainPH_dom-like

TRIO ITSN1 FRMPD1 APBA2 ARHGEF18 CDC42BPB OPHN1 TYK2 ITSN2 ENAH VAV2

3.72e-0442614011IPR011993
DomainFYrich_C

KMT2B KMT2D

5.50e-0451402IPR003889
DomainFYrich_N

KMT2B KMT2D

5.50e-0451402IPR003888
DomainFYRC

KMT2B KMT2D

5.50e-0451402SM00542
DomainFYRN

KMT2B KMT2D

5.50e-0451402SM00541
DomainPKNOX/Meis_N

MEIS1 MEIS2

5.50e-0451402IPR032453
DomainFYRN

KMT2B KMT2D

5.50e-0451402PF05964
DomainFYRC

KMT2B KMT2D

5.50e-0451402PF05965
DomainFYRC

KMT2B KMT2D

5.50e-0451402PS51543
DomainFYRN

KMT2B KMT2D

5.50e-0451402PS51542
DomainMeis_PKNOX_N

MEIS1 MEIS2

5.50e-0451402PF16493
DomainHMG_box

KMT2D PBRM1 BBX TOX3

6.66e-04531404PF00505
DomainHMG

KMT2D PBRM1 BBX TOX3

7.15e-04541404SM00398
DomainWD40

WDR33 WDR81 AMBRA1 THOC3 FBXW8 GTF3C2 TLE3 PRPF19

7.59e-042591408PF00400
Domain-

KMT2D PBRM1 BBX TOX3

7.67e-045514041.10.30.10
DomainGATASE_TYPE_1

PFAS CTPS2

8.20e-0461402PS51273
DomainNOL1_NOP2_SUN

NSUN4 NSUN6

8.20e-0461402PS01153
DomainRCMT

NSUN4 NSUN6

8.20e-0461402IPR023267
DomainGATASE

PFAS CTPS2

8.20e-0461402IPR017926
Domain-

PCLO ITSN1 RAB11FIP1 C2CD2L ITSN2 CCDC33

8.78e-0414814062.60.40.150
DomainWD40

WDR33 WDR81 AMBRA1 THOC3 FBXW8 GTF3C2 TLE3 PRPF19

9.47e-042681408SM00320
DomainWD40_repeat

WDR33 WDR81 AMBRA1 THOC3 FBXW8 GTF3C2 TLE3 PRPF19

1.04e-032721408IPR001680
DomainDesmosomal_cadherin

DSG1 DSG4

1.14e-0371402IPR009122
DomainSAM_MT_RSMB_NOP

NSUN4 NSUN6

1.14e-0371402PS51686
DomainWD_REPEATS_1

WDR33 WDR81 AMBRA1 THOC3 FBXW8 GTF3C2 TLE3 PRPF19

1.20e-032781408PS00678
DomainWD_REPEATS_2

WDR33 WDR81 AMBRA1 THOC3 FBXW8 GTF3C2 TLE3 PRPF19

1.22e-032791408PS50082
DomainWD_REPEATS_REGION

WDR33 WDR81 AMBRA1 THOC3 FBXW8 GTF3C2 TLE3 PRPF19

1.22e-032791408PS50294
DomainDH_1

TRIO ITSN1 ARHGEF18 VAV2

1.28e-03631404PS00741
DomainHMG_box_dom

KMT2D PBRM1 BBX TOX3

1.44e-03651404IPR009071
DomainC2_dom

PCLO ITSN1 RAB11FIP1 C2CD2L ITSN2 CCDC33

1.49e-031641406IPR000008
DomainMeTrfase_RsmB/NOP2

NSUN4 NSUN6

1.52e-0381402IPR001678
DomainMethyltr_RsmB-F

NSUN4 NSUN6

1.52e-0381402PF01189
DomainPH

TRIO ITSN1 ARHGEF18 CDC42BPB OPHN1 ITSN2 VAV2

1.72e-032291407PF00169
DomainWD40_repeat_dom

WDR33 WDR81 AMBRA1 THOC3 FBXW8 GTF3C2 TLE3 PRPF19

1.82e-032971408IPR017986
DomainMIR

POMT2 ITPR1

2.41e-03101402PF02815
Domain-

PFAS CTPS2

2.41e-031014023.40.50.880
DomainSTI1

ST13 ST13P5

2.41e-03101402SM00727
DomainMIR_motif

POMT2 ITPR1

2.41e-03101402IPR016093
DomainMIR

POMT2 ITPR1

2.41e-03101402PS50919
DomainMIR

POMT2 ITPR1

2.41e-03101402SM00472
DomainEF-hand_4

ITSN1 ITSN2

2.41e-03101402PF12763
DomainSTI1_HS-bd

ST13 ST13P5

2.41e-03101402IPR006636
DomainKazal_2

SLCO1B3 SLCO1B1 WFIKKN1

2.46e-03361403PF07648
Domain-

TRIO ITSN1 APBA2 ARHGEF18 CDC42BPB OPHN1 ITSN2 ENAH VAV2

2.78e-0339114092.30.29.30
PathwayREACTOME_CDC42_GTPASE_CYCLE

TRIO ITSN1 PAK5 WDR81 GIT2 CDC42BPB OPHN1 VAV2

2.31e-051551078M41808
PathwayREACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

BCL9L BCL9 KMT2D TLE3

4.12e-05261074MM14793
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

KIF13B GPRASP1 CACNA1E NCOA3 AMPD2 MIA3 HDAC4 TRIO ITSN1 PAK5 HNRNPM WDR81 ARHGEF18 GIT2 DBN1 BCL9 CDC42BPB ATF6B ZEB2 KHSRP ZNF462 EEF2 PBRM1 NCAN ENAH AFDN

3.00e-149631442628671696
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

NCOA3 HNRNPM RUVBL2 KHSRP ZNF462 ARID1B KMT2D PBRM1 PRPF19 ZFHX3 MED23 PSPC1

1.51e-102201441235785414
Pubmed

Interaction network of human early embryonic transcription factors.

BCL9L NCOA3 NCOA6 KMT2B HDAC4 BCL9 ZEB2 ZNF462 ARID1B KMT2D PBRM1 TLE3 ZFHX3

2.90e-093511441338297188
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

GPRASP1 BCL9L SYNRG AMPD2 MIA3 TRIO DSG1 PCLO HNRNPM APBA2 DBN1 RUVBL2 CDC42BPB ST13 KHSRP ITPR1 C2CD2L ENAH AFDN ST13P5 SLC16A7

1.08e-0811391442136417873
Pubmed

Human transcription factor protein interaction networks.

BCL9L NCOA3 TCF4 NCOA6 KMT2B OFD1 WDR33 MRPL10 DBN1 BCL9 RUVBL2 ZEB2 ZIC3 ZNF462 ARID1B KMT2D PBRM1 BBX GTF3C2 TLE3 PRPF19 ZFHX3 CHD6

2.48e-0814291442335140242
Pubmed

A census of human transcription factors: function, expression and evolution.

NCOA3 TCF4 TBX21 ATF6B ZEB2 MEIS1 MEIS2 HSF5 KMT2D BBX TP63 BARHL2 SETBP1 TOX3 ZFHX3 ZNF91 ONECUT3 FOXF1

4.50e-089081441819274049
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

BCL9L AMPD2 MIA3 AMER1 HDAC4 OFD1 DBN1 RAB11FIP1 RUVBL2 ARID1B MOB1B TRAPPC10 AFDN

4.90e-084461441324255178
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

NCOA3 NCOA6 BCL9 ARID1B KMT2D TLE3 TP63

5.75e-0883144728794006
Pubmed

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

NCOA6 KMT2B HDAC4 RUVBL2 ARID1B KMT2D PBRM1 CHD6

3.23e-07157144830186101
Pubmed

TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation.

TCF4 ST13 ZEB2 PBRM1 BBX CHD6 ST13P5

3.77e-07109144733554859
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

NCOA3 NCOA6 MRPL10 TBC1D25 BCL9 ACSL4 RNF123 ARID1B KMT2D PBRM1 TLE3 ITSN2 DSG4 CHD6

4.68e-076381441431182584
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

SYNRG NCOA6 KMT2B WDR33 DBN1 RUVBL2 KHSRP ARID1B KMT2D GTF3C2 ENAH AFDN MED23

5.26e-075491441338280479
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

CACNA1E HDAC4 TRIO DSG1 INTS7 OPHN1 KHSRP ITPR1 EEF2 PBRM1 CHD6 HSD17B4

7.47e-074751441231040226
Pubmed

Functional proteomics mapping of a human signaling pathway.

NCOA6 KMT2B HIPK1 ITSN1 ST13 ZEB2 SEC24D RNF123 ARID1B KMT2D PBRM1 AFDN CHD6

1.19e-065911441315231748
Pubmed

Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases.

NCOA6 KMT2B KMT2D

1.38e-066144317021013
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

BCL9L NCOA3 NCOA6 WDR33 BCL9 ARID1B KMT2D PBRM1 TLE3

1.92e-06268144933640491
Pubmed

ASCOM controls farnesoid X receptor transactivation through its associated histone H3 lysine 4 methyltransferase activity.

NCOA6 KMT2B KMT2D

2.40e-067144319556342
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

BCL9L NCOA3 NCOA6 HDAC4 WDR33 HNRNPM BCL9 ARID1B KMT2D TLE3 PSPC1

3.49e-064571441132344865
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SYNRG NCOA6 RTL6 KMT2B OFD1 TRIO LAMB3 AMBRA1 PFAS TBC1D25 BCL9 CDC42BPB C2CD2L TYK2 KMT2D SGSM2 SNX8

3.55e-0611051441735748872
Pubmed

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

NCOA3 DSG1 HNRNPM AMBRA1 RUVBL2 KHSRP EEF2 BBX GTF3C2 PRPF19 CHD6 HSD17B4 PSPC1

3.68e-066551441335819319
Pubmed

Constitutive scaffolding of multiple Wnt enhanceosome components by Legless/BCL9.

BCL9L BCL9 TLE3

3.83e-068144328296634
Pubmed

Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress.

HNRNPM RUVBL2 KHSRP PBRM1 PRPF19 HSD17B4 PSPC1

4.75e-06159144722751105
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

NCOA6 GIT2 CDC42BPB C2CD2L ZNF462 NLN SETBP1 CHD6

4.79e-06225144812168954
Pubmed

Genome-wide association analysis identifies 13 new risk loci for schizophrenia.

TCF4 ZEB2 NSUN6 PBRM1 NCAN SNX8

6.47e-06109144623974872
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

PCED1A HDAC4 DSG1 WDR33 PAK5 HNRNPM PFAS GIT2 RAB11FIP1 RUVBL2 CDC42BPB KHSRP KPTN STK16 RNF123 TLE3 PRPF19 AFDN

6.49e-0612841441817353931
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

TRIO DSG1 PCLO HNRNPM PFAS DBN1 THOC3 RUVBL2 ST13 KHSRP EEF2 PBRM1 GTF3C2 ENAH PRPF19 AFDN HSD17B4 MED23 PSPC1

7.19e-0614251441930948266
Pubmed

FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligands.

KMT2B ENAH ZFHX3

8.17e-061014439171351
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

KIF13B CACNA1E AMER1 WDR33 PCLO ITSN1 HNRNPM DBN1 ZEB2 KHSRP ACSL4 EEF2 BBX ITSN2 PRPF19 CHD6 HSD17B4 PSPC1 DNAH8

8.50e-0614421441935575683
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

NCOA3 AMPD2 HNRNPM RAB11FIP1 KHSRP EEF2 PBRM1 GTF3C2 TLE3 ENAH AFDN

8.63e-065031441116964243
Pubmed

Maintenance of silent chromatin through replication requires SWI/SNF-like chromatin remodeler SMARCAD1.

WDR33 HNRNPM RUVBL2 PBRM1 GTF3C2 PRPF19

9.26e-06116144621549307
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

SYNRG TRIO HNRNPM RUVBL2 KHSRP ZNF462 EEF2 SETBP1 PRPF19 DSG4 PGM2

1.04e-055131441125798074
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

NSUN4 WDR33 HNRNPM DBN1 THOC3 RUVBL2 KHSRP ZNF462 EEF2 ARID1B BBX PRPF19 CHD6 HSD17B4 MED23 PSPC1

1.14e-0510821441638697112
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

MIA3 AMER1 HDAC4 TRIO FRMPD1 ARHGEF18 CASC2 CDC42BPB TYK2 ZNF462 SLC35A4 SGSM2 TLE3 SETBP1 ENAH TOX3 ZFHX3 CHD6 VAV2

1.33e-0514891441928611215
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

TCF4 NSUN4 HIPK1 FRMPD1 ZEB2 MEIS1 KHSRP ACSL4 FBXW8 KMT2D BBX GTF3C2 TLE3 FOXF1

1.40e-058571441425609649
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

NCOA3 NCOA6 KMT2B HDAC4 BCL9 RUVBL2 ZEB2 KHSRP EEF2 ARID1B KMT2D TLE3 PRPF19 HSD17B4 MED23 PSPC1

1.45e-0511031441634189442
Pubmed

Intersectin deficiency impairs cortico-striatal neurotransmission and causes obsessive-compulsive behaviors in mice.

ITSN1 ITSN2

1.70e-052144237603735
Pubmed

Phosphorylated cortactin recruits Vav2 guanine nucleotide exchange factor to activate Rac3 and promote invadopodial function in invasive breast cancer cells.

NCOA3 VAV2

1.70e-052144228356423
Pubmed

KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis.

KMT2D TP63

1.70e-052144229440247
Pubmed

Modulation of transporter activity of OATP1B1 and OATP1B3 by the major active components of Radix Ophiopogonis.

SLCO1B3 SLCO1B1

1.70e-052144229944058
Pubmed

SLCO1B1 and SLCO1B3 genetic mutations in Taiwanese patients with Rotor syndrome.

SLCO1B3 SLCO1B1

1.70e-052144236964102
Pubmed

Exon Inclusion Modulates Conformational Plasticity and Autoinhibition of the Intersectin 1 SH3A Domain.

ITSN1 ITSN2

1.70e-052144231031201
Pubmed

Intersectin associates with synapsin and regulates its nanoscale localization and function.

ITSN1 ITSN2

1.70e-052144229078407
Pubmed

Meis2 as a critical player in MN1-induced leukemia.

MEIS2 MN1

1.70e-052144228960191
Pubmed

Contribution of OATP1B1 and OATP1B3 to the disposition of sorafenib and sorafenib-glucuronide.

SLCO1B3 SLCO1B1

1.70e-052144223340295
Pubmed

Kabuki syndrome stem cell models reveal locus specificity of histone methyltransferase 2D (KMT2D/MLL4).

KMT2B KMT2D

1.70e-052144235640156
Pubmed

Further Studies to Support the Use of Coproporphyrin I and III as Novel Clinical Biomarkers for Evaluating the Potential for Organic Anion Transporting Polypeptide 1B1 and OATP1B3 Inhibition.

SLCO1B3 SLCO1B1

1.70e-052144229777022
Pubmed

Down-regulation of OATP1B proteins correlates with hyperbilirubinemia in advanced cholestasis.

SLCO1B3 SLCO1B1

1.70e-052144226191226
Pubmed

Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions.

BCL9L BCL9

1.70e-052144215371335
Pubmed

The transcription factors ZEB2 and T-bet cooperate to program cytotoxic T cell terminal differentiation in response to LCMV viral infection.

TBX21 ZEB2

1.70e-052144226503446
Pubmed

Utility of Oatp1a/1b-knockout and OATP1B1/3-humanized mice in the study of OATP-mediated pharmacokinetics and tissue distribution: case studies with pravastatin, atorvastatin, simvastatin, and carboxydichlorofluorescein.

SLCO1B3 SLCO1B1

1.70e-052144224194513
Pubmed

Clinical significance of LAMB3 and COL7A1 mRNA in esophageal squamous cell carcinoma.

COL7A1 LAMB3

1.70e-052144218331784
Pubmed

Evaluation of organic anion transporting polypeptide 1B1 and 1B3 humanized mice as a translational model to study the pharmacokinetics of statins.

SLCO1B3 SLCO1B1

1.70e-052144224855184
Pubmed

Vertebrate intersectin1 is repurposed to facilitate cortical midline connectivity and higher order cognition.

ITSN1 ITSN2

1.70e-052144223447614
Pubmed

Preclinical Mouse Models To Study Human OATP1B1- and OATP1B3-Mediated Drug-Drug Interactions in Vivo.

SLCO1B3 SLCO1B1

1.70e-052144226474710
Pubmed

Effects of anthocyans on the expression of organic anion transporting polypeptides (SLCOs/OATPs) in primary human hepatocytes.

SLCO1B3 SLCO1B1

1.70e-052144225578040
Pubmed

Prediction of organic anion-transporting polypeptide 1B1- and 1B3-mediated hepatic uptake of statins based on transporter protein expression and activity data.

SLCO1B3 SLCO1B1

1.70e-052144224989890
Pubmed

The human intersectin genes and their spliced variants are differentially expressed.

ITSN1 ITSN2

1.70e-052144211690630
Pubmed

Expression of organic anion-transporting polypeptides 1B1 and 1B3 in ovarian cancer cells: relevance for paclitaxel transport.

SLCO1B3 SLCO1B1

1.70e-052144221719246
Pubmed

Organic anion transporting polypeptide 1B1 (OATP1B1) and OATP1B3: genetic variability and haplotype analysis in white Canadians.

SLCO1B3 SLCO1B1

1.70e-052144220877131
Pubmed

TANGO1 recruits ERGIC membranes to the endoplasmic reticulum for procollagen export.

COL7A1 MIA3

1.70e-052144226568311
Pubmed

BCL9/BCL9L promotes tumorigenicity through immune-dependent and independent mechanisms in triple negative breast cancer.

BCL9L BCL9

1.70e-052144233767438
Pubmed

MEIS1 and MEIS2 Expression and Prostate Cancer Progression: A Role For HOXB13 Binding Partners in Metastatic Disease.

MEIS1 MEIS2

1.70e-052144229716922
Pubmed

Transport of fluorescent chenodeoxycholic acid via the human organic anion transporters OATP1B1 and OATP1B3.

SLCO1B3 SLCO1B1

1.70e-052144216534140
Pubmed

Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3.

SLCO1B3 SLCO1B1

1.70e-052144218321482
Pubmed

St13 protects against disordered acinar cell arachidonic acid pathway in chronic pancreatitis.

ST13 ST13P5

1.70e-052144235562743
Pubmed

Interaction of oral antidiabetic drugs with hepatic uptake transporters: focus on organic anion transporting polypeptides and organic cation transporter 1.

SLCO1B3 SLCO1B1

1.70e-052144218314419
Pubmed

OATP 1B1/1B3 expression in hepatocellular carcinomas treated with orthotopic liver transplantation.

SLCO1B3 SLCO1B1

1.70e-052144221691816
Pubmed

Myeloid ecotropic viral integration site 1 (MEIS) 1 involvement in embryonic implantation.

MEIS1 MEIS2

1.70e-052144218408019
Pubmed

Linking organic anion transporting polypeptide 1B1 and 1B3 (OATP1B1 and OATP1B3) interaction profiles to hepatotoxicity - The hyperbilirubinemia use case.

SLCO1B3 SLCO1B1

1.70e-052144228063966
Pubmed

Targeted Resequencing of 29 Candidate Genes and Mouse Expression Studies Implicate ZIC3 and FOXF1 in Human VATER/VACTERL Association.

ZIC3 FOXF1

1.70e-052144226294094
Pubmed

Control of mouse limb initiation and antero-posterior patterning by Meis transcription factors.

MEIS1 MEIS2

1.70e-052144234035267
Pubmed

Long-lasting inhibitory effects of cyclosporin A, but not tacrolimus, on OATP1B1- and OATP1B3-mediated uptake.

SLCO1B3 SLCO1B1

1.70e-052144222240838
Pubmed

Human organic anion transporter 1B1 and 1B3 function as bidirectional carriers and do not mediate GSH-bile acid cotransport.

SLCO1B3 SLCO1B1

1.70e-052144217412826
Pubmed

Genetic analysis of epidermolysis bullosa: identification of mutations in LAMB3 and COL7A1 genes in three families.

COL7A1 LAMB3

1.70e-052144223769655
Pubmed

Targeting BCL9/BCL9L enhances antigen presentation by promoting conventional type 1 dendritic cell (cDC1) activation and tumor infiltration.

BCL9L BCL9

1.70e-052144238811552
Pubmed

Visualization of hepatic uptake transporter function in healthy subjects by using gadoxetic acid-enhanced MR imaging.

SLCO1B3 SLCO1B1

1.70e-052144222771883
Pubmed

Establishment of a set of double transfectants coexpressing organic anion transporting polypeptide 1B3 and hepatic efflux transporters for the characterization of the hepatobiliary transport of telmisartan acylglucuronide.

SLCO1B3 SLCO1B1

1.70e-052144218180273
Pubmed

Adaptor proteins intersectin 1 and 2 bind similar proline-rich ligands but are differentially recognized by SH2 domain-containing proteins.

ITSN1 ITSN2

1.70e-052144223936226
Pubmed

Structure of human drug transporters OATP1B1 and OATP1B3.

SLCO1B3 SLCO1B1

1.70e-052144237723174
Pubmed

Comparison of methylation episignatures in KMT2B- and KMT2D-related human disorders.

KMT2B KMT2D

1.70e-052144235506254
Pubmed

Effects of Rifampin, a potent inducer of drug-metabolizing enzymes and an inhibitor of OATP1B1/3 transport, on the single dose pharmacokinetics of anacetrapib.

SLCO1B3 SLCO1B1

1.70e-052144223670789
Pubmed

Type VII collagen regulates expression of OATP1B3, promotes front-to-rear polarity and increases structural organisation in 3D spheroid cultures of RDEB tumour keratinocytes.

COL7A1 SLCO1B3

1.70e-052144224357722
Pubmed

Bosentan is a substrate of human OATP1B1 and OATP1B3: inhibition of hepatic uptake as the common mechanism of its interactions with cyclosporin A, rifampicin, and sildenafil.

SLCO1B3 SLCO1B1

1.70e-052144217496208
Pubmed

Rotor Syndrome

SLCO1B3 SLCO1B1

1.70e-052144223236639
Pubmed

Bcl9/Bcl9l are critical for Wnt-mediated regulation of stem cell traits in colon epithelium and adenocarcinomas.

BCL9L BCL9

1.70e-052144220682801
Pubmed

Hybrid selection of transcribed sequences from microdissected DNA: isolation of genes within amplified region at 20q11-q13.2 in breast cancer.

NCOA3 NCOA6

1.70e-05214428758910
Pubmed

Expression Patterns of Organic Anion Transporting Polypeptides 1B1 and 1B3 Protein in Human Pediatric Liver.

SLCO1B3 SLCO1B1

1.70e-052144227098745
Pubmed

Introduction of aromatic ring-containing substituents in cyclic nucleotides is associated with inhibition of toxin uptake by the hepatocyte transporters OATP 1B1 and 1B3.

SLCO1B3 SLCO1B1

1.70e-052144224740327
Pubmed

UGT-dependent regioselective glucuronidation of ursodeoxycholic acid and obeticholic acid and selective transport of the consequent acyl glucuronides by OATP1B1 and 1B3.

SLCO1B3 SLCO1B1

1.70e-052144231299240
Pubmed

In vitro OATP1B1 and OATP1B3 inhibition is associated with observations of benign clinical unconjugated hyperbilirubinemia.

SLCO1B3 SLCO1B1

1.70e-052144223886114
Pubmed

OATP1B1/1B3 activity in plated primary human hepatocytes over time in culture.

SLCO1B3 SLCO1B1

1.70e-052144221787759
Pubmed

Mutation of ARHGAP9 in patients with coronary spastic angina.

TRIO OPHN1 ITSN2 VAV2

1.86e-0538144419911011
Pubmed

Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping.

NCOA3 NCOA6 ARID1B KMT2D TLE3

1.88e-0578144528611094
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

NCOA3 SYNRG NCOA6 KMT2B ITSN1 DBN1 BCL9 EEF2 KMT2D TLE3 TRAPPC10 AFDN MN1

2.16e-057741441315302935
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

TRIO DSG1 WDR33 ITSN1 MRPL10 ARHGEF18 GIT2 ST13 OPHN1 ITSN2 ENAH HSD17B4 PSPC1 VAV2

2.91e-059161441432203420
Pubmed

H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation.

NCOA6 KMT2B KMT2D

3.74e-0516144324368734
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

NCOA3 AMPD2 PCLO ZEB2 TYK2 ARID1B KMT2D PBRM1 TLE3

4.50e-05398144935016035
Pubmed

MLL3 and MLL4 Methyltransferases Bind to the MAFA and MAFB Transcription Factors to Regulate Islet β-Cell Function.

NCOA6 KMT2B KMT2D

4.53e-0517144326180087
Pubmed

Preincubation With Everolimus and Sirolimus Reduces Organic Anion-Transporting Polypeptide (OATP)1B1- and 1B3-Mediated Transport Independently of mTOR Kinase Inhibition: Implication in Assessing OATP1B1- and OATP1B3-Mediated Drug-Drug Interactions.

SLCO1B3 SLCO1B1

5.09e-053144231047942
Pubmed

Multiple Genetic Modifiers of Bilirubin Metabolism Involvement in Significant Neonatal Hyperbilirubinemia in Patients of Chinese Descent.

SLCO1B3 SLCO1B1

5.09e-053144226146841
InteractionGSC interactions

BCL9L NCOA3 TBX21 BCL9 ZEB2 ZNF462 ARID1B KMT2D TLE3 ZFHX3 DSG4

2.55e-118714211int:GSC
InteractionFEV interactions

NCOA3 NCOA6 KMT2B BCL9 ZEB2 ZNF462 ARID1B KMT2D PBRM1 GTF3C2 TLE3 ZFHX3 CHD6

2.08e-0920314213int:FEV
InteractionPAX9 interactions

BCL9L NCOA3 NCOA6 TBX21 BCL9 ARID1B KMT2D PBRM1 TLE3 ZFHX3

2.84e-0813014210int:PAX9
InteractionEGR2 interactions

BCL9L NCOA3 NCOA6 HDAC4 BCL9 ZEB2 ZNF462 ARID1B KMT2D TLE3 ZFHX3

3.63e-0817114211int:EGR2
InteractionTLX1 interactions

NCOA3 BCL9 ZEB2 MEIS1 MEIS2 ZNF462 ARID1B KMT2D PBRM1 TLE3 ZFHX3

4.60e-0817514211int:TLX1
InteractionTLX3 interactions

BCL9L NCOA3 NCOA6 TBX21 DBN1 BCL9 MEIS1 ARID1B KMT2D PBRM1 TLE3 ZFHX3 CHD6

1.50e-0729114213int:TLX3
InteractionGATA2 interactions

NCOA3 NCOA6 BCL9 ZEB2 ARID1B KMT2D PBRM1 TLE3 TRAPPC10 ZFHX3 CHD6

1.71e-0719914211int:GATA2
InteractionAR interactions

BCL9L NCOA3 TCF4 NCOA6 HDAC4 WDR33 HNRNPM RAB11FIP1 BCL9 RUVBL2 KHSRP ZNF462 EEF2 ARID1B KMT2D MLH3 PBRM1 TLE3 PRPF19 ZFHX3 MED23 PSPC1 VAV2

4.49e-0799214223int:AR
InteractionHNF4A interactions

NCOA3 NCOA6 KMT2B HDAC4 ZEB2 STK16 ZNF462 ARID1B KMT2D PBRM1 GTF3C2 MED23

5.92e-0727514212int:HNF4A
InteractionTLX2 interactions

DBN1 BCL9 MEIS1 ARID1B KMT2D PBRM1 TLE3 ZFHX3 CHD6

7.49e-071421429int:TLX2
InteractionTBR1 interactions

BCL9L NCOA3 BCL9 RNF123 ARID1B KMT2D TLE3 ZFHX3

1.37e-061131428int:TBR1
InteractionSP7 interactions

BCL9L NCOA3 NCOA6 KMT2B WDR33 BCL9 ZEB2 RNF123 ARID1B KMT2D PBRM1 TLE3

1.70e-0630414212int:SP7
InteractionCRX interactions

BCL9L NCOA3 BCL9 ZEB2 STK16 ZNF462 ARID1B KMT2D PBRM1 TLE3 ZFHX3

1.91e-0625414211int:CRX
InteractionPAX6 interactions

NCOA3 NCOA6 BCL9 ZEB2 MEIS2 ZNF462 ARID1B KMT2D PBRM1 GTF3C2 TLE3 ZFHX3 CHD6

2.00e-0636614213int:PAX6
InteractionSOX9 interactions

NCOA3 NCOA6 BCL9 ARID1B KMT2D PBRM1 TLE3

5.63e-06971427int:SOX9
InteractionHNF1B interactions

NCOA3 BCL9 RUVBL2 ZEB2 ARID1B KMT2D PBRM1 TLE3 ZFHX3

8.27e-061901429int:HNF1B
InteractionGCM1 interactions

NCOA3 HDAC4 BCL9 ARID1B KMT2D TLE3

8.41e-06681426int:GCM1
InteractionMYOD1 interactions

NCOA3 TCF4 BCL9 ZEB2 ARID1B KMT2D PBRM1 TLE3 EXOC3L1

9.79e-061941429int:MYOD1
InteractionPAX8 interactions

NCOA3 BCL9 ZEB2 ARID1B KMT2D PBRM1 TLE3

1.37e-051111427int:PAX8
InteractionTBXT interactions

NCOA3 NCOA6 BCL9 ZEB2 ARID1B KMT2D TLE3

1.83e-051161427int:TBXT
InteractionSCARNA22 interactions

HNRNPM RUVBL2 KHSRP PBRM1 PRPF19 HSD17B4 PSPC1

2.04e-051181427int:SCARNA22
InteractionETS1 interactions

NCOA3 MEIS1 ARID1B KMT2D PBRM1 TLE3 MED23

2.40e-051211427int:ETS1
InteractionSOX7 interactions

NCOA3 ZEB2 ARID1B KMT2D PBRM1 TLE3

2.48e-05821426int:SOX7
InteractionPAX7 interactions

NCOA3 BCL9 ARID1B KMT2D TLE3 ZFHX3 CHD6

2.82e-051241427int:PAX7
InteractionERG interactions

NCOA3 NCOA6 HIPK1 HNRNPM DBN1 BCL9 ARID1B KMT2D TLE3

2.96e-052231429int:ERG
InteractionTEAD1 interactions

ZEB2 ZNF462 ARID1B KMT2D PBRM1 TLE3 TP63 ZFHX3

3.58e-051761428int:TEAD1
InteractionNUP35 interactions

BCL9L NCOA3 NCOA6 HDAC4 WDR33 HNRNPM BCL9 ARID1B KMT2D TLE3 AFDN PSPC1

4.77e-0542414212int:NUP35
InteractionSOX10 interactions

NCOA3 TCF4 BCL9 ARID1B KMT2D PBRM1

4.77e-05921426int:SOX10
InteractionKIF20A interactions

WDR33 S100A7L2 PCLO CD109 HNRNPM AMBRA1 DBN1 RUVBL2 CDC42BPB ZEB2 KHSRP ITPR1 ZNF462 ACSL4 NLN EEF2 PRPF19 HSD17B4 MGAT5B PGM2

4.92e-05105214220int:KIF20A
InteractionGATA3 interactions

NCOA3 HDAC4 TBX21 BCL9 ARID1B KMT2D PBRM1 TLE3

5.50e-051871428int:GATA3
InteractionSOX17 interactions

NCOA3 NCOA6 BCL9 ARID1B KMT2D PBRM1

5.72e-05951426int:SOX17
InteractionPPARG interactions

NCOA3 TCF4 NCOA6 HDAC4 HNRNPM RUVBL2 KHSRP ARID1B KMT2D PBRM1

6.57e-0530714210int:PPARG
InteractionKLF5 interactions

NCOA3 NCOA6 BCL9 ARID1B KMT2D PBRM1 TLE3 TP63

7.39e-051951428int:KLF5
InteractionFOS interactions

NCOA3 NCOA6 DBN1 BCL9 KHSRP ARID1B KMT2D PBRM1 DSG4 HSD17B4

7.51e-0531214210int:FOS
InteractionFAM222A interactions

MEIS1 MEIS2 FBXW8

9.30e-05131423int:FAM222A
InteractionETV4 interactions

NCOA3 BCL9 ARID1B KMT2D TP63

1.27e-04691425int:ETV4
InteractionSYDE1 interactions

KIF13B HDAC4 DSG1 WDR33 TBC1D25 AFDN

1.29e-041101426int:SYDE1
InteractionCHD6 interactions

TCF4 HDAC4 RNF123 TLE3 CHD6

1.45e-04711425int:CHD6
InteractionC16orf90 interactions

RNF123 TP63

1.47e-0431422int:C16orf90
InteractionSOX2 interactions

BCL9L NCOA3 ATP6V1B1 NCOA6 INTS7 HNRNPM DBN1 BCL9 RUVBL2 ZEB2 MEIS2 KHSRP ZNF462 EEF2 ARID1B KMT2D PBRM1 TLE3 TP63 PRPF19 ZFHX3 CHD6 PGM2

1.51e-04142214223int:SOX2
InteractionSETD1B interactions

NCOA6 KMT2B HDAC4 KMT2D TP63

1.88e-04751425int:SETD1B
InteractionWWTR1 interactions

SYNRG NCOA6 DBN1 RUVBL2 KHSRP ARID1B KMT2D GTF3C2 TP63 ENAH AFDN

2.04e-0442214211int:WWTR1
InteractionTWIST1 interactions

TCF4 ST13 ZEB2 ZIC3 PBRM1 BBX CHD6

2.06e-041701427int:TWIST1
InteractionNFIX interactions

KMT2B ZEB2 ARID1B KMT2D PBRM1 GTF3C2 TLE3 ZFHX3

2.11e-042271428int:NFIX
InteractionKLF3 interactions

KMT2B ZEB2 ARID1B KMT2D PBRM1 TLE3 ZFHX3 CHD6

2.17e-042281428int:KLF3
InteractionAMER3 interactions

AMER1 RNF123

2.93e-0441422int:AMER3
InteractionALG13 interactions

NCOA3 MIA3 WDR33 BCL9 ARID1B KMT2D TLE3

3.22e-041831427int:ALG13
InteractionLHX2 interactions

BCL9L BCL9 ZEB2 ARID1B KMT2D PBRM1 ZFHX3

3.22e-041831427int:LHX2
InteractionSMAD3 interactions

NCOA3 NCOA6 KMT2B HDAC4 GIT2 ZEB2 ARID1B ZFHX3 PSPC1 VAV2 CCDC33

3.33e-0444714211int:SMAD3
InteractionMEN1 interactions

KIF13B NCOA6 KMT2B WDR33 HNRNPM RUVBL2 KHSRP ZNF462 ARID1B KMT2D PBRM1 GTF3C2 TLE3 SETBP1 PRPF19 AFDN HSD17B4 PSPC1

3.36e-04102914218int:MEN1
InteractionIRF4 interactions

NCOA3 OFD1 ARID1B KMT2D PBRM1

3.38e-04851425int:IRF4
InteractionPAX2 interactions

NCOA3 BCL9 ARID1B KMT2D TLE3

3.38e-04851425int:PAX2
InteractionFBXW7 interactions

NCOA3 NCOA6 NSUN4 HNRNPM LAMB3 GIT2 RUVBL2 CDC42BPB ZEB2 KCTD17 EEF2 KMT2D GTF3C2 TP63 SNX8 PRPF19 CHD6 KCTD2 MED23 PSPC1

3.40e-04121514220int:FBXW7
InteractionTLE3 interactions

BCL9L NCOA3 TCF4 BCL9 ARID1B KMT2D TLE3 ZFHX3 CHD6 MED23

3.40e-0437614210int:TLE3
InteractionKDM1A interactions

NCOA3 ATP6V1B1 TCF4 KMT2B OFD1 RUVBL2 ZEB2 ZNF462 KMT2D GTF3C2 TLE3 ITSN2 ZFHX3 CHD6 MED23 PSPC1 CCDC33

3.43e-0494114217int:KDM1A
InteractionPYGO2 interactions

BCL9L BCL9 KMT2D TLE3

3.61e-04481424int:PYGO2
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

PCLO ITSN1 RAB11FIP1 ITSN2 CCDC33

1.32e-0636975823
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

TRIO ITSN1 ARHGEF18 ITSN2 VAV2

2.76e-0566975722
GeneFamilyWD repeat domain containing

WDR33 WDR81 AMBRA1 THOC3 FBXW8 GTF3C2 TLE3 PRPF19

8.30e-05262978362
GeneFamilyAtaxins|Trinucleotide repeat containing

NCOA3 KMT2D TOX3

3.16e-0425973775
GeneFamilyNOP2/Sun RNA methyltransferase family

NSUN4 NSUN6

5.88e-047972664
GeneFamilyDesmosomal cadherins

DSG1 DSG4

5.88e-0479721188
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZEB2 ZFHX3

2.86e-0315972529
CoexpressionGRYDER_PAX3FOXO1_ENHANCERS_IN_TADS

POMT2 TRIO LAMB3 GIT2 ZEB2 MEIS1 MEIS2 ITPR1 NSUN6 TLE3 SETBP1 ITSN2 ENAH TOX3 EID1 CHD6 KCTD2 MN1 FOXF1

2.59e-06100914319M157
ToppCellIPF-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

NCOA3 TCF4 TRIO ARHGEF18 ITPR1 SETBP1 SNX8 VAV2

1.60e-071871428af1327559f7e01bec070881cae52834917c3da65
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-T_lymphocytic-type_I_NK_T_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KIF13B SYNRG OFD1 TBX21 APBA2 DBN1 ZEB2 TRAPPC10

2.20e-0719514280a72b8446399807ace5b6c72f865bb40dbd9e92d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FRMPD1 NRG2 XKR6 OPHN1 ITPR1 ACSL4 TOX3

1.91e-061811427e0abf2707d9e0aa942c657eef7d2cbcd02f060dd
ToppCellControl-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

NCOA3 TCF4 TRIO ARHGEF18 SETBP1 SNX8 VAV2

2.37e-0618714274e64be635f445276e71f2937f33f041c3a4204ab
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

NCOA3 TCF4 TRIO RAB11FIP1 ITPR1 SNX8 VAV2

2.64e-06190142760bb6aaea9691d07295f61c14d1650f5041a0f9c
ToppCellCOPD-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

NCOA3 TCF4 TRIO RAB11FIP1 SETBP1 SNX8 VAV2

2.64e-0619014271e85ee686ff6dd27c69415d524d54fa825b1daad
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-Immature_INs|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

TCF4 LAMB3 ARID1B ENAH TOX3 AFDN ZFHX3

2.64e-061901427842760bfe0a52e67bad800efa7d99448a4a23ebb
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

TCF4 TRIO RAB11FIP1 ITPR1 SETBP1 ITSN2 VAV2

2.92e-06193142708696a99309f5b088692ddac8cca35413b5e810d
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TCF4 CD109 SLCO1B3 MEIS2 TOX3 EXOC3L1 AFDN

2.92e-0619314276e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCellLPS-IL1RA-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TCF4 CD109 SLCO1B3 MEIS2 TOX3 EXOC3L1 AFDN

3.02e-06194142743f92b0533e26633dc94cce554045d641ef8fd76
ToppCellLPS-IL1RA-Endothelial-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TCF4 CD109 SLCO1B3 MEIS2 TOX3 EXOC3L1 AFDN

3.02e-0619414271d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCellLPS_only-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TCF4 CD109 SLCO1B3 MEIS2 TOX3 EXOC3L1 AFDN

3.02e-06194142758f069efdefa0366033764446b9d6ffd4a17807e
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TCF4 CD109 SLCO1B3 MEIS2 TOX3 EXOC3L1 AFDN

3.02e-061941427bfd92ec75facb0ba55c31e5f2e089d983b3d0169
ToppCellIPF-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

CD109 ZEB2 MEIS1 OPHN1 ABHD17C MN1 FOXF1

3.24e-0619614278f0f72ead06abe02b575e443552eacc2151077ef
ToppCelldroplet-Tongue-TONGUE-1m-Epithelial-basal_cell_of_epidermis|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL7A1 LAMB3 MEIS1 MEIS2 EEF2 TP63 EID1

3.24e-061961427d4df86ce289835e76763213641989fde77935a16
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-35|World / Primary Cells by Cluster

TCF4 ZEB2 MEIS2 ZNF462 ENAH ZNF91 MN1

3.46e-061981427de5214a85fe017eb23d4aa8af624464f062ec57e
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal|GW16 / Sample Type, Dataset, Time_group, and Cell type.

CACNA1E PCLO PAK5 ZEB2 OPHN1 NLN MN1

3.70e-06200142784e4565d28a02700bf7f6730d1b3a58744ca0aea
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-GABAergic_neurons|GW26 / Sample Type, Dataset, Time_group, and Cell type.

CACNA1E TCF4 PCLO PAK5 ZEB2 AFDN ZNF91

3.70e-062001427bad32a95b759fad509401b07bc96a56687c2a592
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KIF13B TBX21 PBRM1 MOB1B AGXT DNAH8

5.89e-061401426af9efcbaeeae69fcdac4a15fa244728b65915564
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

TCF4 TRIO RAB11FIP1 ZEB2 ITPR1 SETBP1

1.40e-0516314266bed27d2f67a430a847da5eb47878d14b4949c45
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

MIA3 HIPK1 RNF123 ARID1B BBX AFDN

1.56e-05166142632d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCellBronchial_Biopsy-Immune-Mast_cells|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

GPRASP1 HDAC4 NRG2 XKR6 MEIS2 ZNF462

1.67e-05168142645ccc0cb42d21f4853190e8e9ed9a54aefefe738
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_dendritic-CD1c-positive_myeloid_dendritic_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TCF4 TRIO CD109 LAMB3 SNX8 AFDN

1.78e-051701426cc66ac6846c58be9493eb270644ee3ce0f86cfea
ToppCellfacs-Marrow-T_cells-18m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E TCF4 ITSN1 NRG2 ITPR1 SEC24D

2.17e-05176142674f851a398c7562dd713bc0d8d488c0037243112
ToppCellnormal_Lymph_Node-Myeloid_cells-pDCs|normal_Lymph_Node / Location, Cell class and cell subclass

TCF4 PFAS RAB11FIP1 ZEB2 OPHN1 SETBP1

2.17e-051761426476794ef75ce5ab732d78cfeb4944e2f841e3e92
ToppCellfacs-Marrow-T_cells-18m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E TCF4 ITSN1 NRG2 ITPR1 SEC24D

2.17e-05176142631b5459a978d5cdde0af03a77401e0464d8c95ba
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TCF4 CD109 MEIS2 EXOC3L1 MN1 MGAT5B

2.17e-051761426dc5a22f9d1347f157bdd93e6e5769b983deccf1a
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TCF4 MEIS1 ITPR1 FRRS1 SNX8 DNAH8

2.87e-0518514263563dd39ec58d3273f95f5bb36b9ccdc0aafb63a
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)-D231|Adult / Lineage, Cell type, age group and donor

TCF4 CD109 MEIS1 MEIS2 MGAT5B FOXF1

2.87e-05185142607f9f38f0739d7c830641723a38385550ac1ac92
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

XKR6 OPHN1 ITPR1 ACSL4 TOX3 SLC16A7

3.14e-051881426bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCell368C-Epithelial_cells-Epithelial-I_(AT1)-|368C / Donor, Lineage, Cell class and subclass (all cells)

LAMB3 AMBRA1 ABHD17C KCTD2 MED23 SLC23A3

3.14e-051881426c74771584b3ba9561a99a54bf55a9203ddf8eff8
ToppCellCOPD-Endothelial-VE_Capillary_A|Endothelial / Disease state, Lineage and Cell class

NCOA3 XKR6 MEIS1 OPHN1 ZFHX3 FOXF1

3.14e-0518814261aa0e35b1c28ac847886fece16c3ef7fc6fcdd51
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

XKR6 OPHN1 ITPR1 ACSL4 TOX3 SLC16A7

3.14e-051881426eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCell368C-Epithelial_cells-Epithelial-I_(AT1)|368C / Donor, Lineage, Cell class and subclass (all cells)

LAMB3 AMBRA1 ABHD17C KCTD2 MED23 SLC23A3

3.14e-0518814269155b9a92496e75646778c025b02947e9e9ec73a
ToppCellCTRL-Lymphoid-B_cell|Lymphoid / Disease state, Lineage and Cell class

NCOA3 TCF4 TRIO SETBP1 SNX8 VAV2

3.23e-05189142614f3a8c0f4f057ad4e6839b4c3eeaf956d6dc92e
ToppCellIPF-Epithelial-Basal|Epithelial / Disease state, Lineage and Cell class

COL7A1 CD109 LAMB3 THOC3 ACSL4 TP63

3.33e-0519014264f15842b424eefadbfe451875e517cf70e29607f
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4/8-lo-Tgd_CRTAM|lymph-node_spleen / Manually curated celltypes from each tissue

KIF13B TBX21 APBA2 MRPL10 DBN1 ZEB2

3.43e-051911426f802a4686ecf00e8302047bfe23356f24b266cf8
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4/8-lo|lymph-node_spleen / Manually curated celltypes from each tissue

KIF13B TBX21 APBA2 MRPL10 DBN1 ZEB2

3.53e-0519214264d72b9264ed62e0c08cde4078061b348253f6989
ToppCellLPS-IL1RA+antiTNF-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD109 SLCO1B3 MEIS2 TOX3 EXOC3L1 AFDN

3.53e-05192142604f5a2e3dd6beff027b89d66eefdd92036e041af
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD109 SLCO1B3 MEIS2 TOX3 EXOC3L1 AFDN

3.53e-051921426c07d7b40b2aa4eb27ac85801c014a656e2fd01dc
ToppCellLPS-antiTNF-Endothelial-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD109 SLCO1B3 MEIS2 TOX3 EXOC3L1 AFDN

3.64e-05193142602f633b016ab19bfa65bfd0cf32f000549a62148
ToppCellLPS-antiTNF-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD109 SLCO1B3 MEIS2 TOX3 EXOC3L1 AFDN

3.64e-0519314265122b1ffba42de190061be34ecdc6176f84e56a3
ToppCellCF-Lymphoid-B_cell|Lymphoid / Disease state, Lineage and Cell class

NCOA3 TRIO SETBP1 SNX8 DNAH8 VAV2

3.64e-0519314267ebf20344a9a154fd2cffa281526867fcf0aded3
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NCOA3 TCF4 ITPR1 ARID1B SETBP1 VAV2

3.74e-051941426ff661419b697aef51a53fdeac8d37d870d65f491
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TCF4 SLCO1B3 MEIS2 TOX3 EXOC3L1 AFDN

3.74e-0519414260b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NCOA3 TCF4 RAB11FIP1 ZEB2 ITPR1 SETBP1

3.85e-051951426481989d2e5bd2582da3d86b0155c4d6615317067
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NCOA3 TCF4 RAB11FIP1 ZEB2 ITPR1 SETBP1

3.85e-0519514266108a27523d1b93a7fbe35cb95704a5ad9071e3c
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-IPC/newborn-38|World / Primary Cells by Cluster

TCF4 DBN1 MEIS2 ZNF462 BBX SETBP1

3.96e-05196142638da0751941adca650fe9b383d9f343153978eb5
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-IPC/newborn|World / Primary Cells by Cluster

TCF4 DBN1 MEIS2 ZNF462 BBX SETBP1

3.96e-051961426721650a08d260faf530dbd52d4e9275d27f3bac2
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn|World / Primary Cells by Cluster

TCF4 PAK5 MEIS2 ZNF462 ZNF91 MN1

3.96e-0519614269401bd84798f0ea3e986e94135a9e1dc5643330f
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_capillary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TCF4 CD109 MEIS1 MEIS2 EXOC3L1 FOXF1

4.08e-05197142681718164c9802ee20c860ffbda7e62d5e9a76f16
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TCF4 COL7A1 NRG2 THOC3 TP63 SETBP1

4.08e-0519714261e915957ea6a4550ecb9d6ee4b232aa5800faf20
ToppCellCOVID-19-lung-Capillary_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

TCF4 CD109 MEIS1 MEIS2 EXOC3L1 FOXF1

4.19e-05198142645419f2804b4be79bae6632e71c54e1af482d115
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TCF4 ZEB2 MEIS1 MEIS2 EID1 FOXF1

4.19e-051981426ebceb11f50b8a6ebb7629fdbd3d31fb131ace6fd
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

TRIO AMBRA1 XKR6 MEIS1 OPHN1 ARID1B

4.31e-05199142694b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell3'-GW_trimst-1|3' / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DBN1 MEIS2 EEF2 ENAH EID1 FOXF1

4.31e-051991426ecfb6381e2971a3e355e661a6df0021914485e74
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PCLO MEIS1 MEIS2 TP63 ENAH AFDN

4.43e-05200142697f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-OPC_related|10w / Sample Type, Dataset, Time_group, and Cell type.

TCF4 MEIS1 BBX SETBP1 TOX3 AFDN

4.43e-0520014268f5d98f962ddd8c4658c89ff8a2894de1228562a
ToppCellInfluenza-Influenza_Severe-Myeloid-cDC|Influenza_Severe / Disease, condition lineage and cell class

CD109 LYSMD4 RUVBL2 OPHN1 FRRS1 CTPS2

4.43e-052001426b8415a68ad6f4fea562236a1b0da0dc376d874fb
ToppCellmild-B_intermediate|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

NCOA3 TCF4 ARID1B SETBP1 ITSN2 DNAH8

4.43e-052001426fe815824e9e4be3f3db73610e3814a7fd533da65
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal-Cortical_neuron|GW16 / Sample Type, Dataset, Time_group, and Cell type.

CACNA1E PCLO ZEB2 MEIS2 OPHN1 MN1

4.43e-05200142619055194a5e0ea122f1b8fc62df44813f6843c95
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal|GW26 / Sample Type, Dataset, Time_group, and Cell type.

CACNA1E TCF4 PAK5 ZEB2 ZNF91 MN1

4.43e-052001426306926cb7a847871641f02e03d52dc56fd55711c
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-OPC_related-Oligodendrocyte/OPC|10w / Sample Type, Dataset, Time_group, and Cell type.

TCF4 MEIS1 BBX SETBP1 TOX3 AFDN

4.43e-052001426345f1eac498cc87fd7bf08e7312608b2d6fe1dd7
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PCLO MEIS1 MEIS2 TP63 ENAH AFDN

4.43e-052001426ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Papillary_Renal_Cell_Carcinoma-9|TCGA-Kidney / Sample_Type by Project: Shred V9

FRMPD1 ZIC3 TOMM40L AGRP ZNF98

6.54e-051321425f1ef63a4842ab6ca584a9dcc2dd5b2108fc990aa
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-midbrain/hindbrain_cells|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

FREM3 BARHL2 RTL9 EXOC3L1 ONECUT3

1.35e-041541425df1b58a20af73fa79c6c069c0117a9ffd85b476f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BCL9L TCF4 CD109 MEIS2 MN1

1.35e-041541425e51a5114f0ec38f997f5b8bbf3a7770f98595474
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NRG2 XKR6 OPHN1 ITPR1 TOX3

1.52e-0415814257960337d87afecf2692ab65e5991f052ceddfacc
ToppCellCOVID-CD4-CD4_Treg|COVID / Condition, Cell_class and T cell subcluster

KIF13B AMPD2 BCL9 KCTD17 KMT2D

1.57e-041591425037cd97c41eb2f91fd3f69bbb3ffdfd6c0158410
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FRMPD1 OPHN1 ITPR1 ACSL4 TOX3

1.62e-0416014258bcdbcfdf1e0ace6053e8de82762f6e2f86bba7a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FRMPD1 OPHN1 ITPR1 ACSL4 TOX3

1.62e-0416014252d391ba6f7adb55dfa89feecc10cc9ce97e5fe74
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TCF4 TRIO FBXW8 SNX8 VAV2

1.66e-04161142563f0b97c741b610c450f65fa5764d712bfe09ce8
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_4|356C / Donor, Lineage, Cell class and subclass (all cells)

NRG2 KPTN FRRS1 EXOC3L1 SPOCD1

1.71e-0416214257d43d59531cbefe3ac94953b7faf7156b2a31441
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Keratinizing_Cervical_Squamous_Cell_Carcinoma|TCGA-Cervix / Sample_Type by Project: Shred V9

COL7A1 CD109 LAMB3 HSF5 TP63

1.81e-041641425de1646dbcf2a10b48e021acf7dc63e803e6a47ce
ToppCellControl-NK|Control / Disease group and Cell class

TCF4 CD109 MEIS1 ZFHX3 VAV2

2.03e-041681425683d389c8a1e791bfc773e63148115a21a6566db
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL7A1 NRG2 LAMB3 DBN1 TP63

2.14e-0417014250cc20322cb3e3e7bbd4daad8785c99f80e355c16
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PCED1A TBX21 KCTD17 SETBP1 PRPF19

2.14e-04170142532917888c3f1d54302675c1d4de1fd3b7c79af5f
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL7A1 NRG2 LAMB3 DBN1 TP63

2.14e-0417014252d880223d01bde4bf777bd6f50b7d2768489075f
ToppCellAT1-AT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

ASCL5 LAMB3 SLCO1B3 DBN1 ZFHX3

2.26e-0417214250be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

TCF4 TRIO RAB11FIP1 ZEB2 ITPR1

2.32e-041731425d56e337eae727a29cd53cfd628e1b3c0a98e1f51
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FRMPD1 NRG2 OPHN1 ACSL4 TOX3

2.32e-0417314254bc6d93716f093b460c8b047199db8cab5fea720
ToppCell(6)_Endothelial_cells-(6)_Endothelial-E|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

CD109 MEIS1 MEIS2 SETBP1 FOXF1

2.39e-0417414254a1b67ce5ea353b3f81f59fa57da07668146afca
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NCOA3 KMT2B RAB11FIP1 SETBP1 ITSN2

2.39e-041741425ebe6ce173ad12d4a2afa39f8d6185c0e4f97fb1e
ToppCellNasal_Brush-Epithelial-Basal_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

COL7A1 PAK5 LAMB3 TP63 SPOCD1

2.52e-041761425fc5787946f5a10056d326d070620575ae4081836
ToppCellNasal_Brush-Epithelial-Basal_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

COL7A1 PAK5 LAMB3 TP63 SPOCD1

2.52e-0417614255daaba0853afe7d20d4635169ccd4f96e735b938
ToppCellCOVID-19-lung-B_cells|lung / Disease (COVID-19 only), tissue and cell type

NCOA3 XKR6 ITPR1 SETBP1 DNAH8

2.58e-041771425f54691e5558091c1734ab15153a10bff15ed171e
ToppCellControl-Myeloid-pDC|Control / Disease state, Lineage and Cell class

TCF4 OFD1 PFAS MOB1B SETBP1

2.58e-0417714253940663bb5b45b2ca9f772550380a516c53e410b
ToppCellCOVID-19-B_cells-Activated_B_cells|COVID-19 / group, cell type (main and fine annotations)

NCOA3 XKR6 ITPR1 SETBP1 DNAH8

2.58e-041771425653bb62a3744d4024ab3186ee01d410ed62832a6
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

KIF13B NCOA3 MEIS2 HSF5 MLH3

2.58e-04177142582fdd6185b368f54f03de389427cbe3071d21a99
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL7A1 LAMB3 WFIKKN1 TP63 ZNF98

2.58e-04177142575cb2067a3f2d1b5a964890b02b604d1e79bd163
ToppCellControl-Myeloid-pDC|Myeloid / Disease state, Lineage and Cell class

TCF4 OFD1 PFAS MOB1B SETBP1

2.58e-041771425e82115bfc32c7b689460fbc5caeb983c1aabe30f
ToppCellControl-Myeloid-pDC|World / Disease state, Lineage and Cell class

TCF4 OFD1 PFAS MOB1B SETBP1

2.65e-04178142520ef63d925e67ddd5955832312ca8574a6f838a4
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCED1A KIF13B PCLO SEC24D ENAH

2.65e-041781425fcbbcc44271515de1969b4732b6441c012693d5f
ToppCellCOVID-19-kidney-vSMC/Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

MEIS1 MEIS2 SETBP1 ZFHX3 PGM2

2.72e-041791425111b1084f73306bdeffaaf240e7dbb4f5bf33de1
ToppCellCOPD-Myeloid-pDC|Myeloid / Disease state, Lineage and Cell class

TCF4 OFD1 PFAS MOB1B SETBP1

2.72e-04179142529b058c5e33fda9f0d738c074bdb67ff16b9b6d5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FRMPD1 OPHN1 ITPR1 ACSL4 TOX3

2.72e-041791425666072c0e8448dbaec1683d18368ec2502453f90
ToppCellIPF-Myeloid-pDC|Myeloid / Disease state, Lineage and Cell class

TCF4 OFD1 PFAS MOB1B SETBP1

2.79e-0418014250f8567aa835d4e3a52f6631ae15216eca18a030c
ToppCellfacs-Marrow-B-cells-3m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E TCF4 ZEB2 ITPR1 SEC24D

2.79e-041801425bf8d13d4db1af55b8c9fe16aaccf8743e000e005
ToppCellfacs-Marrow-B-cells-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E TCF4 ZEB2 ITPR1 SEC24D

2.79e-041801425839defb40f7cfb2711e9025194de636533f51bcd
ToppCellIPF-Lymphoid-B|World / Disease state, Lineage and Cell class

NCOA3 ARHGEF18 XKR6 ITPR1 SETBP1

2.79e-04180142530f9398c9b784f49470847a025bac90687e997a1
ComputationalGenes in the cancer module 453.

GPRASP1 CD109 KMT2D ITSN2 VAV2

1.64e-0544795MODULE_453
ComputationalGenes in the cancer module 11.

GPRASP1 APBA2 NRG2 FAM131A DBN1 BCL9 MEIS2 KCTD17 ITPR1 NCAN SETBP1 TM7SF2 PRPF19

1.40e-045407913MODULE_11
ComputationalGenes in the cancer module 66.

GPRASP1 APBA2 NRG2 FAM131A DBN1 BCL9 MEIS2 KCTD17 ITPR1 NCAN SETBP1 TM7SF2 PRPF19

1.74e-045527913MODULE_66
ComputationalGenes in the cancer module 100.

GPRASP1 APBA2 NRG2 FAM131A DBN1 MEIS2 KCTD17 ITPR1 NCAN SETBP1 TM7SF2 PRPF19

5.74e-045447912MODULE_100
ComputationalCNS genes.

GPRASP1 APBA2 NRG2 FAM131A DBN1 MEIS2 KCTD17 ITPR1 NCAN SETBP1 TM7SF2 PRPF19

5.93e-045467912MODULE_137
DrugQuinidine hydrochloride monohydrate [6151-40-2]; Down 200; 10.6uM; PC3; HT_HG-U133A

TCF4 WDR33 ITSN1 AMBRA1 DBN1 C2CD2L ACSL4 TLE3 SETBP1 ZFHX3

4.84e-07198142105793_DN
DrugAcemetacin [53164-05-9]; Down 200; 9.6uM; PC3; HT_HG-U133A

POMT2 NCOA3 TCF4 KMT2B ITPR1 C2CD2L SEC24D SETBP1 ZFHX3 PRMT7

5.07e-07199142106361_DN
Drugfullerene C60

CACNA1E NCOA3 TCF4 NCOA6 COL7A1 AMPD2 TRIO INTS7 ITSN1 APBA2 NRG2 LAMB3 ARHGEF18 SLCO1B3 PFAS RAB11FIP1 LY6G5C CDC42BPB C2CD2L BBX SGSM2 SNX8 TRAPPC10 EXOC3L1 PRMT7 CCDC33

1.78e-06149814226ctd:C069837
Drug17-AAG; Up 200; 1uM; PC3; HG-U133A

NCOA3 TCF4 COL7A1 ITSN1 AMBRA1 ARHGEF18 GIT2 C2CD2L SEC24D

2.62e-061861429432_UP
DrugFurosemide [54-31-9]; Up 200; 12uM; HL60; HG-U133A

KMT2B APBA2 AMBRA1 ITPR1 ACSL4 EID1 TM7SF2 SLC16A7

2.83e-0519214281580_UP
DrugAzaguanine-8 [134-58-7]; Down 200; 26.2uM; MCF7; HT_HG-U133A

SYNRG ITSN1 LAMB3 BCL9 MEIS1 C2CD2L TLE3 TRAPPC10

3.05e-0519414281670_DN
DrugHarmol hydrochloride monohydrate [40580-83-4]; Down 200; 15.8uM; PC3; HT_HG-U133A

KIF13B NCOA3 TRIO HIPK1 ITSN1 RAB11FIP1 MEIS1 PRMT7

3.28e-0519614287320_DN
DrugDO 897/99; Down 200; 8.2uM; MCF7; HT_HG-U133A

HDAC4 GIT2 DBN1 BCL9 MEIS1 C2CD2L MLH3 TLE3

3.40e-0519714287462_DN
DrugAmidopyrine [58-15-1]; Down 200; 17.2uM; PC3; HT_HG-U133A

POMT2 KIF13B KMT2B PCLO BCL9 ITPR1 SGSM2 TM7SF2

3.40e-0519714282060_DN
DrugMetampicillin sodium salt [6489-61-8]; Down 200; 10.4uM; HL60; HG-U133A

NCOA3 GIT2 ZEB2 ITPR1 ACSL4 BBX ITSN2 EID1

3.65e-0519914281440_DN
DrugMetoprolol-(+,-) (+)-tartrate salt [56392-17-7]; Up 200; 5.8uM; HL60; HT_HG-U133A

COL7A1 NRG2 SLCO1B1 KCTD17 KMT2D SETBP1 AGXT ZFHX3

3.65e-0519914282543_UP
Drug(5-(3-(4-(2-bromo-5-fluorophenoxy)piperidin-1-yl)isoxazol-5-yl)-2H-tetrazol-2-yl)acetic acid

SLCO1B3 SLCO1B1

3.86e-0521422ctd:C561635
DiseaseMalignant neoplasm of breast

NCOA3 NCOA6 COL7A1 HDAC4 FRMPD1 CD109 FAM131A DBN1 SLCO1B1 ZEB2 MEIS1 EEF2 ARID1B NSUN6 KMT2D PBRM1 CSF3 TLE3 SETBP1 ITSN2 TOX3 EXOC3L1 SPOCD1

9.34e-10107413723C0006142
DiseaseBreast Carcinoma

NCOA3 COL7A1 CD109 SLCO1B1 ZEB2 MEIS1 EEF2 ARID1B NSUN6 KMT2D PBRM1 CSF3 TLE3 SETBP1 ITSN2 TOX3

4.65e-0953813716C0678222
DiseaseMammary Carcinoma, Human

NCOA3 COL7A1 CD109 SLCO1B1 ZEB2 MEIS1 EEF2 NSUN6 KMT2D CSF3 TLE3 SETBP1 ITSN2 TOX3

1.72e-0752513714C4704874
DiseaseMammary Neoplasms, Human

NCOA3 COL7A1 CD109 SLCO1B1 ZEB2 MEIS1 EEF2 NSUN6 KMT2D CSF3 TLE3 SETBP1 ITSN2 TOX3

1.72e-0752513714C1257931
DiseaseMammary Neoplasms

NCOA3 COL7A1 CD109 SLCO1B1 ZEB2 MEIS1 EEF2 NSUN6 KMT2D CSF3 TLE3 SETBP1 ITSN2 TOX3

1.80e-0752713714C1458155
Diseasetestosterone measurement

NCOA6 MIA3 AMER1 ASCL5 WDR81 LAMB3 SLCO1B3 NAA38 SLCO1B1 RUVBL2 OPHN1 TYK2 PNMA6F ARID1B BBX GTF3C2 RTL9 ZFHX3 MED23 SPOCD1

1.87e-06127513720EFO_0004908
DiseaseNeurodevelopmental Disorders

TCF4 TRIO CDC42BPB ITPR1 ARID1B SETBP1

4.91e-06931376C1535926
DiseaseParanoia

TCF4 TYK2 DNAH8

1.57e-05111373C1456784
DiseaseHYPERBILIRUBINEMIA, ROTOR TYPE, DIGENIC

SLCO1B3 SLCO1B1

2.14e-0521372C4016905
DiseaseRotor Syndrome

SLCO1B3 SLCO1B1

2.14e-0521372C0220991
DiseaseRotor syndrome

SLCO1B3 SLCO1B1

2.14e-0521372cv:C0220991
DiseaseHYPERBILIRUBINEMIA, ROTOR TYPE

SLCO1B3 SLCO1B1

2.14e-0521372237450
DiseaseBladder Neoplasm

HDAC4 FBXW8 KMT2D CSF3 NCAN CHD6

5.06e-051401376C0005695
DiseaseMalignant neoplasm of urinary bladder

HDAC4 FBXW8 KMT2D CSF3 NCAN CHD6

5.26e-051411376C0005684
Diseasecolorectal cancer (is_marker_for)

AMER1 EEF2 PBRM1 CTPS2 BARHL2 ZFHX3

9.55e-051571376DOID:9256 (is_marker_for)
DiseaseColorectal Carcinoma

COL7A1 CD109 LAMB3 SLCO1B3 ZEB2 ACSL4 MLH3 TOMM40L TP63 SETBP1 SNX8 DNAH8

1.11e-0470213712C0009402
Diseasecalcium measurement

NCOA6 HDAC4 CD109 WDR81 ITPR1 ARID1B BBX TLE3 RTL9 SNX8 ZFHX3

1.75e-0462813711EFO_0004838
Diseasetriacylglycerol 52:6 measurement

LY6G5C BBX NCAN

2.09e-04251373EFO_0010418
Diseaseanti-human herpes virus 7 antibody measurement

BCL9L TBX21

2.12e-0451372EFO_0011038
Diseasebilirubin metabolic disorder (implicated_via_orthology)

SLCO1B3 SLCO1B1

2.12e-0451372DOID:2741 (implicated_via_orthology)
Diseasegamma wave measurement

NRG2 GIT2

2.12e-0451372EFO_0008388
DiseaseUnipolar Depression

PCLO TBX21 BCL9 FREM3 TYK2 ACSL4 CSF3

2.16e-042591377C0041696
Diseasebreast carcinoma (is_marker_for)

NCOA3 KMT2D AFDN ZFHX3

2.56e-04661374DOID:3459 (is_marker_for)
Diseaseaggressive behaviour measurement, ADHD symptom measurement

TCF4 NCOA6 XKR6 BBX

2.88e-04681374EFO_0007826, EFO_0007860
Diseaselung small cell carcinoma (is_implicated_in)

LAMB3 KMT2D PBRM1

2.95e-04281373DOID:5409 (is_implicated_in)
Diseaseserum non-albumin protein measurement

MIA3 TBX21 XKR6 CDC42BPB TLE3 TP63 SNX8 AFDN

2.95e-043611378EFO_0004568
Diseasecongenital heart disease (implicated_via_orthology)

KMT2B ITPR1 KMT2D CHD6

3.04e-04691374DOID:1682 (implicated_via_orthology)
Diseasebilirubin metabolic disorder (is_implicated_in)

SLCO1B3 SLCO1B1

3.17e-0461372DOID:2741 (is_implicated_in)
Diseaserestless legs syndrome (implicated_via_orthology)

MEIS1 MEIS2

5.88e-0481372DOID:0050425 (implicated_via_orthology)
Diseasedeoxycholic acid glucuronide measurement

SLCO1B3 SLCO1B1

5.88e-0481372EFO_0800575
Diseasehand, foot and mouth disease, illness severity status

HDAC4 XKR6

7.54e-0491372EFO_0007294, EFO_0007863
Diseasehexadecenedioate (C16:1-DC) measurement

SLCO1B3 SLCO1B1

7.54e-0491372EFO_0800562
Diseaseinterferon alpha/beta receptor 1 measurement

ITSN1 TYK2

7.54e-0491372EFO_0021850
DiseaseX-21467 measurement

SLCO1B3 SLCO1B1

7.54e-0491372EFO_0020007
Diseaseprostate cancer (is_marker_for)

NCOA3 KMT2B SLCO1B3 EEF2 KMT2D

8.26e-041561375DOID:10283 (is_marker_for)
Diseaseunipolar depression, bipolar disorder

CACNA1E TCF4 PCLO NCAN SETBP1

8.26e-041561375EFO_0003761, MONDO_0004985
Diseaseresponse to simvastatin, myopathy

TBX21 XKR6 SLCO1B1

9.17e-04411373EFO_0004145, GO_1903491
Diseasealopecia

TCF4 HDAC4 OPHN1 ZNF462 BBX SETBP1

9.41e-042411376MONDO_0004907
DiseaseAdenocarcinoma of large intestine

PAK5 CDC42BPB TYK2 MLH3

1.06e-03961374C1319315
DiseaseIntellectual Disability

CACNA1E HDAC4 TRIO MEIS2 ZNF462 SETBP1 MED23 MN1

1.19e-034471378C3714756
Diseasetotal blood protein measurement

NCOA3 SLCO1B1 KMT2D BBX TLE3 TP63 SNX8 AFDN

1.22e-034491378EFO_0004536
DiseasePsychotic Disorders

TCF4 PAK5 BCL9 PBRM1

1.28e-031011374C0033975
DiseaseLeukemia, Myelocytic, Acute

TRIO CSF3 SETBP1 ENAH MN1

1.31e-031731375C0023467
Diseaseglycochenodeoxycholate glucuronide (1) measurement

SLCO1B3 SLCO1B1

1.61e-03131372EFO_0800474
Diseasecolon carcinoma (is_marker_for)

SLCO1B3 KMT2D

1.61e-03131372DOID:1520 (is_marker_for)
DiseaseSkin Abnormalities

ZNF469 TP63

1.61e-03131372C0037268
Diseasesitting height ratio

TCF4 ARID1B ITSN2

1.73e-03511373EFO_0007118
DiseaseBipolar Disorder

TCF4 PCLO DBN1 BCL9 ITPR1 PBRM1 NCAN DNAH8

1.79e-034771378C0005586
Diseasediffuse large B-cell lymphoma

CDC42BPB ITSN2

1.88e-03141372EFO_0000403
DiseaseSitus ambiguus

BCL9L ZIC3

2.16e-03151372C0266642
Diseaseresponse to statin, LDL cholesterol change measurement

SLCO1B1 ZNF98

2.16e-03151372EFO_0007804, GO_0036273
DiseaseX-17654 measurement

SLCO1B1 HSD17B4

2.16e-03151372EFO_0800784
DiseasePontoneocerebellar hypoplasia

AMPD2 PCLO

2.46e-03161372cv:C1261175
DiseaseMultiple congenital anomalies

TP63 SETBP1

2.78e-03171372C0000772
Diseasesphingomyelin 14:0 measurement

PAK5 ZFHX3

2.78e-03171372EFO_0010390
Diseaseautosomal dominant intellectual developmental disorder (is_implicated_in)

KMT2B TRIO

2.78e-03171372DOID:0060307 (is_implicated_in)
Diseasechronotype measurement

TCF4 HDAC4 THOC3 MEIS1 MEIS2 ZNF462 RNF123 KMT2D CSF3 BARHL2 MGAT5B

2.79e-0388213711EFO_0008328
DiseaseAcute Myeloid Leukemia, M1

TRIO CSF3 ENAH MN1

2.79e-031251374C0026998
DiseaseAcute Myeloid Leukemia (AML-M2)

TRIO CSF3 ENAH MN1

2.79e-031251374C1879321
Diseaseobesity (implicated_via_orthology)

TCF4 ITPR1 TYK2 ZFHX3 HSD17B4

3.37e-032151375DOID:9970 (implicated_via_orthology)
Diseaseleukemia (implicated_via_orthology)

MEIS1 MEIS2

3.47e-03191372DOID:1240 (implicated_via_orthology)
Diseaseneuroticism measurement

CACNA1E TCF4 PCLO XKR6 ATF6B ST13 ITPR1 CTPS2 BBX ENAH TOX3

3.51e-0390913711EFO_0007660
Diseasecorneal hysteresis

TCF4 ZNF469

3.85e-03201372EFO_0010066
DiseaseCraniosynostosis

ZNF462 MN1

3.85e-03201372C0010278
Diseaselung non-small cell carcinoma (is_implicated_in)

ARID1B KMT2D PBRM1 ZFHX3

4.08e-031391374DOID:3908 (is_implicated_in)
DiseaseNonorganic psychosis

TCF4 PAK5 PBRM1

4.10e-03691373C0349204
DiseaseHbA1c measurement, response to sulfonylurea

SLCO1B1 TOX3

4.24e-03211372EFO_0004541, EFO_0007922
DiseaseMalignant neoplasm of liver

TCF4 TRIO CSF3 TOX3

4.40e-031421374C0345904
DiseaseLiver neoplasms

TCF4 TRIO CSF3 TOX3

4.40e-031421374C0023903
Diseasebiological sex

TCF4 ITSN1 BARHL2 SETBP1 CCDC33

4.48e-032301375PATO_0000047

Protein segments in the cluster

PeptideGeneStartEntry
PATRGAQMGLAPMEG

AGRP

16

O00253
AQMGLAPMEGIRRPD

AGRP

21

O00253
AGDFDGMSMDLPLPP

AFDN

1376

P55196
LLGGNVRMMLSGGAP

ACSL4

431

O60488
LGQEMMGSLELGPEA

EXOC3L1

346

Q86VI1
MAEMGGLEDLPQPRG

ARHGEF18

841

Q6ZSZ5
MPMGAAERGAGPQSS

ASCL5

1

Q7RTU5
DPTQMGGLSMLLLAG

BBX

201

Q8WY36
PMLSASGLPLGSMGE

CCDC33

796

Q8N5R6
PGPGMMCGAVNNLLS

CACNA1E

2291

Q15878
FMPAMNAVLGSGVPL

BPIFB4

576

P59827
MRPLGPSVMGLAAGV

AMER1

656

Q5JTC6
PNDMEPDGMGSSRKG

GIT2

596

Q14161
ILANMMNGGPAARSG

APBA2

596

Q99767
CGAVPLGRMPSAGMQ

ARID1B

961

Q8NFD5
EPSTMPGDLGLGLRM

AMPD2

311

Q01433
DMGLMNAIGLQPRNP

AMBRA1

1081

Q9C0C7
GMAGMPGLNEILSDP

ST13P5

306

Q8NFI4
GMAGMPGLNEILSDP

ST13

306

P50502
PLISARFGMGSMPNL

ITSN2

111

Q9NZM3
IAMQLPVLGDGMLGD

INTS7

456

Q9NVH2
PSNMGVIFGPTLMRA

OPHN1

521

O60890
AGNMPRQLEMGGLSP

OFD1

831

O75665
RQLEMGGLSPAGDMS

OFD1

836

O75665
DGQQHMGIRAPGPMS

MEIS1

361

O00470
SRSGSGLQEPMMPFG

PAK5

286

Q9P286
MRFMAGPAGSQSLGP

LY6G5C

1

Q5SRR4
PLQGPVDGLVSMGSM

PBRM1

1496

Q86U86
SEQPMMGLSNLSPGP

FAM156A

36

Q8NDB6
NMAFTGGLDPPMGDA

HDAC4

891

P56524
SMAMGTVPGQAPRLA

LYSMD4

261

Q5XG99
LRGGGFLPMTPMAAA

ITPR1

946

Q14643
PTAMIPEAMGSGQQL

HIPK1

776

Q86Z02
HMGIRPAGLQSMPGD

MEIS2

376

O14770
LLGGDMDMGNPGTLS

TCF4

126

P15884
ANSLERMGPAMGPAL

HNRNPM

586

P52272
CMGPVMSGNILVGPE

DSG4

986

Q86SJ6
MAEPTGLLEMSELPG

EID2B

1

Q96D98
MPPGAGLMERIQAIA

MGAT5B

111

Q3V5L5
VMPGEGDLPQMEVGS

EID1

21

Q9Y6B2
SDSPPNLMVSGNMDG

FBXW8

441

Q8N3Y1
ESPLSPVGQPMGMAR

PCLO

4361

Q9Y6V0
GGLPARMGSAVDMAP

PNMA6F

511

A0A0J9YX94
MMGEAAVAAGPCPLR

KPTN

1

Q9Y664
GSLDSPSGMLMNPVE

MLH3

996

Q9UHC1
PSGMLMNPVEDATGD

MLH3

1001

Q9UHC1
MAPTFLLVGMPGLSG

OR51S1

16

Q8NGJ8
NMAMPLGERITGGFL

PCED1A

181

Q9H1Q7
TLAQALGMNMGGAPA

DNAH8

1831

Q96JB1
GGMRRDPAPGFSMLL

NRG2

91

O14511
GNGIMRIPLPGTNCM

MED23

501

Q9ULK4
GLRAAMGPGISRMND

PGM2

61

Q96G03
RKRPMANGLAMAGSP

SLC16A7

141

O60669
ASMPLSPGGQMEEVA

KMT2B

816

Q9UMN6
LGSGNLRMAVMLPEG

MOB1B

36

Q7L9L4
PRGPGSPAEDLMFME

DBN1

411

Q16643
GPGDGMQVLMDLPLS

CDC42BPB

1596

Q9Y5S2
LLDAPCSGMGQRPNM

NSUN6

321

Q8TEA1
PAMRMEAGEAAPPAG

KCTD17

6

Q8N5Z5
PISGADLHGMLEMPD

DSG1

871

Q02413
GELVIPNLMANFGPM

NSUN4

361

Q96CB9
GMSAGLPLGALPEML

TM7SF2

116

O76062
MEAGFPMASGPGIIR

NCOA6

161

Q14686
AGEPMDLGELVGMTP

PRPF19

156

Q9UMS4
PMAGDMNGLSPTQAL

TP63

511

Q9H3D4
SGPGRSGMALMEVNL

CD109

1306

Q6YHK3
PAMMVNLRACSAPGG

C2CD2L

251

O14523
DQHLGPGAMVMPQAA

PRMT7

501

Q9NVM4
IVADSPSGMGPLFMN

CHD6

2456

Q8TD26
PLFMNGLIAGMDLVG

CHD6

2466

Q8TD26
LGFAGMNEMVAPRIG

FRMPD1

1316

Q5SYB0
AMFLGMDLPGLNLPD

FRRS1

496

Q6ZNA5
MMGGGLAEIPGLSIN

HSD17B4

386

P51659
RLPGFAGMINSEMEG

BCL9

561

O00512
MASPAMLGNVESGGP

BCL9

956

O00512
TLMSNPAAAVGMIPG

BCL9

1346

O00512
GMGGIASMPPLTAVA

ITSN1

116

Q15811
RGPMDVQDPMQLRGG

BCL9L

581

Q86UU0
LMGPQGLSPEEMARV

BCL9L

806

Q86UU0
MAGTRGLMLLGPGPV

CASC2

1

Q8IU53
MDTDMAGQLPLGPHL

FAM131A

206

Q6UXB0
MPEPGPRMNGFSLGE

ABHD17C

1

Q6PCB6
SSGSPGMMNGDFRPL

BARHL2

21

Q9NY43
MAGAGPTMLLREENG

NAA38

1

Q9BRA0
ELGMAPALQPTQGAM

CSF3

156

P09919
PMPAGMLIERSSDFG

LAMB3

126

Q13751
IRDMPYMDPSGNNLG

COL7A1

1121

Q02388
PLPLGGSGLMEEMSA

ENAH

436

Q8N8S7
ESGPMGNIMIDPVLG

EEF2

196

P13639
SGDDGRMDMPGLVNL

S100A7L2

21

Q5SY68
MAELQLDPAMAGLGG

KCTD2

1

Q14681
RGELAGPLHPAMGMA

ONECUT3

81

O60422
PGASAMPRAAGMVGL

MN1

271

Q10571
MGPERHLSGAPARMA

MEA1

1

Q16626
MMLDDIVSRGRGGPP

KHSRP

206

Q92945
MFGGKPRNMVLSPEG

GPRASP1

1081

Q5JY77
PMMVELLGPEGQDAG

FREM3

266

P0C091
CPPNSLALEGGLGMM

FOXF1

181

Q12946
EMGPDVLVQTMGAPA

KIF13B

1511

Q9NQT8
IAMGMAQALGPDTPF

RUVBL2

86

Q9Y230
SGDPGRLAGFLMQMD

RTL6

106

Q6ICC9
GELSPILMQDMNPGV

RTL9

201

Q8NET4
LDSGAMSTPLMGAPA

RTL9

406

Q8NET4
GKMLSQPMSTQDPGG

RTL9

716

Q8NET4
GEMSLPLMRAPASGE

RTL9

791

Q8NET4
PSEQMGFLISEMGPA

HSF5

531

Q4G112
MAMEIDSRPGGLPGS

ATP6V1B1

1

P15313
MLMGVKPGEDASGPA

RAB11FIP1

466

Q6WKZ4
SNLPPRIMAAGGLQM

AGXT

31

P21549
MTGRAMDPLPAAAVG

SNX8

1

Q9Y5X2
LGDEGQPVLMDLGSM

STK16

156

O75716
GMVGPLAQDPQSPMA

POMT2

726

Q9UKY4
ASPTGDMAVGSPLMQ

TBC1D25

571

Q3MII6
GSMPLSLGQPVMGIN

SYNRG

411

Q9UMZ2
LVMAPPLEEGLGGAM

MIA3

1041

Q5JRA6
EPPLAMAVTEMLGSG

NCAN

521

O14594
SMDGLLAGPTMPQAP

NCOA3

1291

Q9Y6Q9
AGDMIEMQGFGPSLP

SGSM2

431

O43147
MGNMLRGIGETPIVP

SLCO1B1

176

Q9Y6L6
VSGLLQGMMGLLGSP

SLC23A3

171

Q6PIS1
MMKPAGPLGATATRG

SEC24D

41

O94855
MPAMAPNETLSGRGA

ATF6B

621

Q99941
PGCLLPDGSRMMAVA

NLN

456

Q9BYT8
EMPNREPAGMGLNPF

ZIC3

26

O60481
MPEHNPGNLGGTMRL

CTPS2

436

Q9NRF8
VEGLTSRGPPMMGAG

XKR6

196

Q5GH73
MAAAVAGMLRGGLLP

MRPL10

1

Q7Z7H8
MGPRGAINMGDAFSP

PSPC1

396

Q8WXF1
MAQRPMQALAVGGPL

RNF123

651

Q5XPI4
LQNMEGASSMPGLSP

SPOCD1

26

Q6ZMY3
VGPGPALMLRGMEGA

PFAS

1211

O15067
MGNMLRGIGETPIVP

SLCO1B3

176

Q9NPD5
MAVPAAAMGPSALGQ

THOC3

1

Q96J01
LPSSPGLLMVGEDMQ

nan

211

A8MX80
MSVEDGGMPGLGRPR

SLC35A4

1

Q96G79
NMPSNIGAPLISSMG

TOX3

406

O15405
GMDPIGIMASALRTP

TLE3

346

Q04726
HGMEMLSRLPFPAGG

ZNF469

496

Q96JG9
LPSSPGLLMVGEDMQ

nan

181

A8MV72
MPGTPGSLEMGLLTF

ZNF91

1

Q05481
CPNMTAGDGPLVIMG

WFIKKN1

491

Q96NZ8
LPSSPGLLMVGEDMQ

nan

211

Q8N9G6
LPSSPGLLMVGEDMQ

nan

211

A8MUI8
MGNTLGLAPMGTLPR

TOMM40L

1

Q969M1
MPGPLGSLEMGVLTF

ZNF98

1

A6NK75
PPTAAMMRGVEGPQG

ZNF462

1151

Q96JM2
CRGMAPNGLPNHIMA

GTF3C2

291

Q8WUA4
DASGAGPGPKMVAMQ

VAV2

581

P52735
VSQGPLMGLNPRGMQ

WDR33

771

Q9C0J8
PSAPALGGESDMLGM

TRAPPC10

886

P48553
VGMEAPLLGFPTMNS

ZEB2

441

O60315
HLQGPVSMGLGDMQP

SETBP1

1116

Q9Y6X0
VSMGLGDMQPSLNPP

SETBP1

1121

Q9Y6X0
MLTGTEPMPGSDEGR

TBX21

11

Q9UL17
LQMSGPEVPMGAERG

WDR81

826

Q562E7
SASLRVLGPGMDGIM

TRIO

2771

O75962
GSKPVGDGAQPMAAM

TYK2

11

P29597
AGPMAAMTPALVGGE

ZFHX3

896

Q15911
AMTPALVGGEIPLDM

ZFHX3

901

Q15911
GLGLKPGQSMMGSRD

KMT2D

3151

O14686