Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionchromatin binding

ARID1A FOXA1 GLI3 ARID1B NCOA3

2.63e-05739115GO:0003682
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

CASZ1 FOXA1 POU2F3 NCOA3

1.73e-04560114GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

CASZ1 FOXA1 POU2F3 NCOA3

1.80e-04566114GO:0001216
GeneOntologyMolecularFunctionRNA polymerase core enzyme binding

NCOA3 SPTY2D1

2.70e-0445112GO:0043175
GeneOntologyMolecularFunctiontranscription coactivator activity

ARID1A ARID1B NCOA3

5.22e-04303113GO:0003713
GeneOntologyMolecularFunctionRNA polymerase binding

NCOA3 SPTY2D1

5.63e-0465112GO:0070063
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

CASZ1 FOXA1 GLI3 POU2F3 NCOA3

5.65e-041412115GO:0000981
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

CASZ1 FOXA1 GLI3 POU2F3 NCOA3

6.58e-041459115GO:0000977
GeneOntologyMolecularFunctionnucleosome binding

ARID1A ARID1B

1.27e-0398112GO:0031491
GeneOntologyMolecularFunctionRNA polymerase II-specific DNA-binding transcription factor binding

ARID1A FOXA1 NCOA3

1.32e-03417113GO:0061629
GeneOntologyMolecularFunctiontranscription coregulator activity

ARID1A ARID1B NCOA3

3.09e-03562113GO:0003712
GeneOntologyMolecularFunctionDNA-binding transcription factor binding

ARID1A FOXA1 NCOA3

3.41e-03582113GO:0140297
GeneOntologyMolecularFunctionnuclear receptor binding

ARID1A NCOA3

4.54e-03187112GO:0016922
GeneOntologyMolecularFunctiontranscription factor binding

ARID1A FOXA1 NCOA3

7.02e-03753113GO:0008134
GeneOntologyBiologicalProcesscamera-type eye morphogenesis

TDRD7 ARID1A CASZ1 GLI3

1.44e-06171114GO:0048593
GeneOntologyBiologicalProcesseye morphogenesis

TDRD7 ARID1A CASZ1 GLI3

2.90e-06204114GO:0048592
GeneOntologyBiologicalProcessestrogen receptor signaling pathway

ARID1A FOXA1 NCOA3

3.25e-0657113GO:0030520
GeneOntologyBiologicalProcessneuron fate commitment

CASZ1 FOXA1 GLI3

1.34e-0591113GO:0048663
GeneOntologyBiologicalProcesspositive regulation of intracellular estrogen receptor signaling pathway

FOXA1 NCOA3

1.70e-0512112GO:0033148
GeneOntologyBiologicalProcessanimal organ morphogenesis

TDRD7 ARID1A CASZ1 FOXA1 GLI3 NCOA3

1.89e-051269116GO:0009887
GeneOntologyBiologicalProcesssensory organ morphogenesis

TDRD7 ARID1A CASZ1 GLI3

2.26e-05343114GO:0090596
GeneOntologyBiologicalProcesschromatin remodeling

ARID1A FOXA1 ARID1B NCOA3 SPTY2D1

2.28e-05741115GO:0006338
GeneOntologyBiologicalProcesspositive regulation of cell-cell adhesion

ARID1A FOXA1 GLI3 ARID1B

3.70e-05389114GO:0022409
GeneOntologyBiologicalProcesspositive regulation of intracellular steroid hormone receptor signaling pathway

FOXA1 NCOA3

3.94e-0518112GO:0033145
GeneOntologyBiologicalProcessepithelium development

TDRD7 ARID1A FOXA1 GLI3 POU2F3 NCOA3

4.37e-051469116GO:0060429
GeneOntologyBiologicalProcessnuclear receptor-mediated steroid hormone signaling pathway

ARID1A FOXA1 NCOA3

4.45e-05136113GO:0030518
GeneOntologyBiologicalProcessradial glial cell differentiation

CASZ1 GLI3

4.89e-0520112GO:0060019
GeneOntologyBiologicalProcessepithelial tube morphogenesis

ARID1A FOXA1 GLI3 NCOA3

5.04e-05421114GO:0060562
GeneOntologyBiologicalProcesscamera-type eye development

TDRD7 ARID1A CASZ1 GLI3

5.28e-05426114GO:0043010
GeneOntologyBiologicalProcesspositive regulation of T cell differentiation

ARID1A GLI3 ARID1B

5.28e-05144113GO:0045582
GeneOntologyBiologicalProcesschromatin organization

ARID1A FOXA1 ARID1B NCOA3 SPTY2D1

5.68e-05896115GO:0006325
GeneOntologyBiologicalProcesssteroid hormone receptor signaling pathway

ARID1A FOXA1 NCOA3

6.57e-05155113GO:0043401
GeneOntologyBiologicalProcesspositive regulation of lymphocyte differentiation

ARID1A GLI3 ARID1B

7.49e-05162113GO:0045621
GeneOntologyBiologicalProcessdorsal/ventral neural tube patterning

FOXA1 GLI3

7.71e-0525112GO:0021904
GeneOntologyBiologicalProcesseye development

TDRD7 ARID1A CASZ1 GLI3

8.39e-05480114GO:0001654
GeneOntologyBiologicalProcessvisual system development

TDRD7 ARID1A CASZ1 GLI3

8.60e-05483114GO:0150063
GeneOntologyBiologicalProcesssensory system development

TDRD7 ARID1A CASZ1 GLI3

9.17e-05491114GO:0048880
GeneOntologyBiologicalProcessprotein-DNA complex organization

ARID1A FOXA1 ARID1B NCOA3 SPTY2D1

9.54e-05999115GO:0071824
GeneOntologyBiologicalProcessgland morphogenesis

FOXA1 GLI3 NCOA3

9.91e-05178113GO:0022612
GeneOntologyBiologicalProcessregulation of nucleotide-excision repair

ARID1A ARID1B

1.04e-0429112GO:2000819
GeneOntologyBiologicalProcessbranching morphogenesis of an epithelial tube

FOXA1 GLI3 NCOA3

1.36e-04198113GO:0048754
GeneOntologyBiologicalProcessneural tube development

ARID1A FOXA1 GLI3

1.44e-04202113GO:0021915
GeneOntologyBiologicalProcessnuclear receptor-mediated signaling pathway

ARID1A FOXA1 NCOA3

1.44e-04202113GO:0141193
GeneOntologyBiologicalProcessregulation of intracellular estrogen receptor signaling pathway

FOXA1 NCOA3

1.61e-0436112GO:0033146
GeneOntologyBiologicalProcesspositive regulation of cell adhesion

ARID1A FOXA1 GLI3 ARID1B

1.73e-04579114GO:0045785
GeneOntologyBiologicalProcessregulation of cell-cell adhesion

ARID1A FOXA1 GLI3 ARID1B

1.74e-04580114GO:0022407
GeneOntologyBiologicalProcesspositive regulation of cell differentiation

ARID1A FOXA1 GLI3 ARID1B NCOA3

1.79e-041141115GO:0045597
GeneOntologyBiologicalProcessregulation of mitotic cell cycle

ARID1A FOXA1 ARID1B NABP1

1.91e-04594114GO:0007346
GeneOntologyBiologicalProcessregulation of T cell differentiation

ARID1A GLI3 ARID1B

2.01e-04226113GO:0045580
GeneOntologyBiologicalProcessregulation of G0 to G1 transition

ARID1A ARID1B

2.20e-0442112GO:0070316
GeneOntologyBiologicalProcessneuron fate specification

FOXA1 GLI3

2.20e-0442112GO:0048665
GeneOntologyBiologicalProcessmorphogenesis of an epithelium

ARID1A FOXA1 GLI3 NCOA3

2.24e-04619114GO:0002009
GeneOntologyBiologicalProcessmorphogenesis of a branching epithelium

FOXA1 GLI3 NCOA3

2.28e-04236113GO:0061138
GeneOntologyBiologicalProcesscellular response to steroid hormone stimulus

ARID1A FOXA1 NCOA3

2.37e-04239113GO:0071383
GeneOntologyBiologicalProcessG0 to G1 transition

ARID1A ARID1B

2.42e-0444112GO:0045023
GeneOntologyBiologicalProcesspositive regulation of leukocyte differentiation

ARID1A GLI3 ARID1B

2.46e-04242113GO:1902107
GeneOntologyBiologicalProcesspositive regulation of hemopoiesis

ARID1A GLI3 ARID1B

2.46e-04242113GO:1903708
GeneOntologyBiologicalProcesshormone-mediated signaling pathway

ARID1A FOXA1 NCOA3

2.52e-04244113GO:0009755
GeneOntologyBiologicalProcessneural tube patterning

FOXA1 GLI3

2.53e-0445112GO:0021532
GeneOntologyBiologicalProcessregulation of neuron differentiation

CASZ1 FOXA1 GLI3

2.86e-04255113GO:0045664
GeneOntologyBiologicalProcessmorphogenesis of a branching structure

FOXA1 GLI3 NCOA3

2.96e-04258113GO:0001763
GeneOntologyBiologicalProcessregulation of lymphocyte differentiation

ARID1A GLI3 ARID1B

3.24e-04266113GO:0045619
GeneOntologyBiologicalProcesspositive regulation of stem cell population maintenance

ARID1A NCOA3

3.25e-0451112GO:1902459
GeneOntologyBiologicalProcesspositive regulation of myoblast differentiation

ARID1A ARID1B

3.64e-0454112GO:0045663
GeneOntologyBiologicalProcesscellular response to hormone stimulus

ARID1A FOXA1 ARID1B NCOA3

4.14e-04727114GO:0032870
GeneOntologyBiologicalProcesspositive regulation of T cell activation

ARID1A GLI3 ARID1B

4.17e-04290113GO:0050870
GeneOntologyBiologicalProcesssensory organ development

TDRD7 ARID1A CASZ1 GLI3

4.21e-04730114GO:0007423
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

CASZ1 FOXA1 GLI3 POU2F3 NCOA3

4.52e-041390115GO:0045944
GeneOntologyBiologicalProcesstissue morphogenesis

ARID1A FOXA1 GLI3 NCOA3

4.66e-04750114GO:0048729
GeneOntologyBiologicalProcessembryo development

TDRD7 ARID1A FOXA1 GLI3 NCOA3

5.28e-041437115GO:0009790
GeneOntologyBiologicalProcessmammary gland morphogenesis

GLI3 NCOA3

5.28e-0465112GO:0060443
GeneOntologyBiologicalProcesstranscription initiation-coupled chromatin remodeling

ARID1A ARID1B

5.28e-0465112GO:0045815
GeneOntologyBiologicalProcesspositive regulation of leukocyte cell-cell adhesion

ARID1A GLI3 ARID1B

5.41e-04317113GO:1903039
GeneOntologyBiologicalProcessdouble-strand break repair

ARID1A ARID1B NABP1

5.77e-04324113GO:0006302
GeneOntologyBiologicalProcesspositive regulation of gene expression, epigenetic

ARID1A ARID1B

5.78e-0468112GO:0141137
GeneOntologyBiologicalProcessepigenetic regulation of gene expression

ARID1A ARID1B SPTY2D1

6.09e-04330113GO:0040029
GeneOntologyBiologicalProcesscell fate commitment

CASZ1 FOXA1 GLI3

6.53e-04338113GO:0045165
GeneOntologyBiologicalProcessregulation of stem cell population maintenance

ARID1A NCOA3

7.60e-0478112GO:2000036
GeneOntologyBiologicalProcessepithelial cell differentiation

TDRD7 FOXA1 POU2F3 NCOA3

8.18e-04870114GO:0030855
GeneOntologyBiologicalProcessnegative regulation of cell differentiation

CASZ1 FOXA1 GLI3 NCOA3

8.36e-04875114GO:0045596
GeneOntologyBiologicalProcessresponse to steroid hormone

ARID1A FOXA1 NCOA3

9.24e-04381113GO:0048545
GeneOntologyBiologicalProcessT cell differentiation

ARID1A GLI3 ARID1B

9.31e-04382113GO:0030217
GeneOntologyBiologicalProcessregulation of intracellular steroid hormone receptor signaling pathway

FOXA1 NCOA3

9.44e-0487112GO:0033143
GeneOntologyBiologicalProcesschordate embryonic development

ARID1A FOXA1 GLI3 NCOA3

9.52e-04906114GO:0043009
GeneOntologyBiologicalProcesspositive regulation of lymphocyte activation

ARID1A GLI3 ARID1B

9.52e-04385113GO:0051251
GeneOntologyBiologicalProcessnucleotide-excision repair

ARID1A ARID1B

9.65e-0488112GO:0006289
GeneOntologyBiologicalProcessregulation of cell adhesion

ARID1A FOXA1 GLI3 ARID1B

1.04e-03927114GO:0030155
GeneOntologyBiologicalProcessembryo development ending in birth or egg hatching

ARID1A FOXA1 GLI3 NCOA3

1.05e-03929114GO:0009792
GeneOntologyBiologicalProcessregulation of myoblast differentiation

ARID1A ARID1B

1.05e-0392112GO:0045661
GeneOntologyBiologicalProcessregulation of mitotic cell cycle phase transition

ARID1A ARID1B NABP1

1.08e-03402113GO:1901990
GeneOntologyBiologicalProcessnegative regulation of neuron differentiation

CASZ1 GLI3

1.10e-0394112GO:0045665
GeneOntologyBiologicalProcessregulation of mitotic metaphase/anaphase transition

ARID1A ARID1B

1.12e-0395112GO:0030071
GeneOntologyBiologicalProcesspositive regulation of double-strand break repair

ARID1A ARID1B

1.12e-0395112GO:2000781
GeneOntologyBiologicalProcessintracellular receptor signaling pathway

ARID1A FOXA1 NCOA3

1.19e-03416113GO:0030522
GeneOntologyBiologicalProcessregulation of metaphase/anaphase transition of cell cycle

ARID1A ARID1B

1.20e-0398112GO:1902099
GeneOntologyBiologicalProcessmetaphase/anaphase transition of mitotic cell cycle

ARID1A ARID1B

1.24e-03100112GO:0007091
GeneOntologyBiologicalProcesspositive regulation of leukocyte activation

ARID1A GLI3 ARID1B

1.25e-03423113GO:0002696
GeneOntologyBiologicalProcessregulation of leukocyte differentiation

ARID1A GLI3 ARID1B

1.30e-03429113GO:1902105
GeneOntologyBiologicalProcessmetaphase/anaphase transition of cell cycle

ARID1A ARID1B

1.32e-03103112GO:0044784
GeneOntologyBiologicalProcessregulation of smoothened signaling pathway

FOXA1 GLI3

1.37e-03105112GO:0008589
GeneOntologyBiologicalProcessdorsal/ventral pattern formation

FOXA1 GLI3

1.42e-03107112GO:0009953
GeneOntologyBiologicalProcessmitotic cell cycle

ARID1A FOXA1 ARID1B NABP1

1.45e-031014114GO:0000278
GeneOntologyCellularComponentbBAF complex

ARID1A ARID1B

1.13e-0510112GO:0140092
GeneOntologyCellularComponentnpBAF complex

ARID1A ARID1B

2.28e-0514112GO:0071564
GeneOntologyCellularComponentbrahma complex

ARID1A ARID1B

2.28e-0514112GO:0035060
GeneOntologyCellularComponentnBAF complex

ARID1A ARID1B

3.01e-0516112GO:0071565
GeneOntologyCellularComponentchromatin

ARID1A CASZ1 FOXA1 ARID1B POU2F3 NCOA3

4.22e-051480116GO:0000785
GeneOntologyCellularComponentSWI/SNF complex

ARID1A ARID1B

1.09e-0430112GO:0016514
GeneOntologyCellularComponentSWI/SNF superfamily-type complex

ARID1A ARID1B

1.12e-0396112GO:0070603
GeneOntologyCellularComponentATPase complex

ARID1A ARID1B

2.00e-03129112GO:1904949
GeneOntologyCellularComponenttranscription regulator complex

GLI3 POU2F3 NCOA3

3.21e-03596113GO:0005667
GeneOntologyCellularComponentnuclear protein-containing complex

ARID1A ARID1B NCOA3 NABP1

4.25e-031377114GO:0140513
HumanPhenoHypospadias

ARID1A CASZ1 GLI3 CYP17A1 ARID1B

4.01e-0537775HP:0000047
HumanPhenoDisplacement of the urethral meatus

ARID1A CASZ1 GLI3 CYP17A1 ARID1B

5.17e-0539775HP:0100627
HumanPhenoAbnormal male urethral meatus morphology

ARID1A CASZ1 GLI3 CYP17A1 ARID1B

5.29e-0539975HP:0032076
HumanPhenoHirsutism

ARID1A CASZ1 GLI3 ARID1B

9.95e-0521674HP:0001007
HumanPhenoAbnormality of the urethra

ARID1A CASZ1 GLI3 CYP17A1 ARID1B

1.12e-0446575HP:0000795
HumanPhenoAplasia/hypoplasia of the uterus

GLI3 CYP17A1 ARID1B

1.30e-048173HP:0008684
HumanPhenoHypoplastic fifth fingernail

ARID1A ARID1B

1.46e-041472HP:0008398
HumanPhenoProminent eyelashes

ARID1A ARID1B

2.18e-041772HP:0011231
HumanPhenoOral aversion

ARID1A ARID1B

2.18e-041772HP:0012523
HumanPhenoHypoplastic fifth toenail

ARID1A ARID1B

2.74e-041972HP:0011937
HumanPhenoAbnormal consumption behavior

ARID1A CASZ1 ARID1B NABP1

3.54e-0429974HP:0040202
HumanPhenoShort distal phalanx of finger

ARID1A GLI3 ARID1B

4.06e-0411973HP:0009882
HumanPhenoPapillary thyroid carcinoma

ARID1A ARID1B

4.40e-042472HP:0002895
HumanPhenoAplasia of the uterus

CYP17A1 ARID1B

4.40e-042472HP:0000151
HumanPhenoAplasia/Hypoplasia of the distal phalanges of the hand

ARID1A GLI3 ARID1B

4.59e-0412473HP:0009835
HumanPhenoAbnormal eating behavior

ARID1A CASZ1 ARID1B

5.04e-0412873HP:0100738
HumanPhenoWide nasal base

ARID1A ARID1B

6.02e-042872HP:0012810
HumanPhenoHepatoblastoma

ARID1A ARID1B

6.02e-042872HP:0002884
HumanPhenoDandy-Walker malformation

ARID1A GLI3 ARID1B

6.70e-0414173HP:0001305
HumanPhenoAbnormal nasal base norphology

ARID1A ARID1B

6.91e-043072HP:0012808
HumanPhenoGiant somatosensory evoked potentials

ARID1A GLI3 ARID1B

7.57e-0414773HP:0001312
HumanPhenoAgenesis of corpus callosum

ARID1A CASZ1 GLI3 ARID1B

7.63e-0436574HP:0001274
HumanPhenoAbnormal penis morphology

ARID1A CASZ1 GLI3 CYP17A1 ARID1B

8.66e-0471275HP:0000036
HumanPhenoDecreased circulating cortisol level

GLI3 CYP17A1

8.89e-043472HP:0008163
HumanPhenoPatent ductus arteriosus

ARID1A CASZ1 GLI3 ARID1B

9.08e-0438274HP:0001643
HumanPhenoNeoplasm by histology

ARID1A CASZ1 GLI3 ARID1B

9.17e-0438374HP:0011792
HumanPhenoAbnormality of somatosensory evoked potentials

ARID1A GLI3 ARID1B

9.88e-0416173HP:0007377
HumanPhenoDysplastic corpus callosum

ARID1A CASZ1 GLI3 ARID1B

1.03e-0339574HP:0006989
HumanPhenoAbnormality of the female genitalia

CASZ1 GLI3 CYP17A1 ARID1B NABP1

1.05e-0374175HP:0010460
HumanPhenoAbnormal fourth ventricle morphology

ARID1A GLI3 ARID1B

1.06e-0316573HP:0010950
HumanPhenoDilated fourth ventricle

ARID1A GLI3 ARID1B

1.06e-0316573HP:0002198
HumanPhenoCerebellar cyst

ARID1A GLI3 ARID1B

1.08e-0316673HP:0002350
HumanPhenoAbnormality of skeletal maturation

ARID1A GLI3 CYP17A1 ARID1B

1.14e-0340574HP:0000927
HumanPhenoThick nasal alae

ARID1A ARID1B

1.17e-033972HP:0009928
HumanPhenoAbnormal distal phalanx morphology of finger

ARID1A GLI3 ARID1B

1.24e-0317473HP:0009832
HumanPhenoCryptorchidism

ARID1A CASZ1 GLI3 CYP17A1 ARID1B

1.33e-0378075HP:0000028
HumanPhenoHypertrichosis

ARID1A CASZ1 GLI3 ARID1B

1.36e-0342574HP:0000998
HumanPhenoAbnormal thyroid morphology

ARID1A GLI3 ARID1B

1.43e-0318373HP:0011772
HumanPhenoTetralogy of Fallot

ARID1A CASZ1 ARID1B

1.48e-0318573HP:0001636
HumanPhenoBroad philtrum

ARID1A ARID1B

1.56e-034572HP:0000289
HumanPhenoEnlarged posterior fossa

ARID1A GLI3 ARID1B

1.67e-0319373HP:0005445
HumanPhenoAplasia/Hypoplasia of the vagina

GLI3 CYP17A1

1.70e-034772HP:0011026
HumanPhenoRib fusion

CASZ1 GLI3

1.77e-034872HP:0000902
HumanPhenoHypoplastic fingernail

ARID1A ARID1B

2.16e-035372HP:0001804
HumanPhenoDislocated radial head

GLI3 ARID1B

2.24e-035472HP:0003083
HumanPhenoIntracranial cystic lesion

ARID1A GLI3 ARID1B

2.41e-0321973HP:0010576
HumanPhenoAbnormal hair quantity

ARID1A CASZ1 GLI3 CYP17A1 ARID1B

2.45e-0388875HP:0011362
HumanPhenoAbnormal posterior cranial fossa morphology

ARID1A GLI3 ARID1B

2.48e-0322173HP:0000932
HumanPhenoAbnormality of the radial head

GLI3 ARID1B

2.49e-035772HP:0003995
HumanPhenoThyroid carcinoma

ARID1A ARID1B

2.49e-035772HP:0002890
HumanPhenoCentral nervous system cyst

ARID1A GLI3 ARID1B

2.51e-0322273HP:0030724
HumanPhenoPrimary adrenal insufficiency

GLI3 CYP17A1

2.67e-035972HP:0008207
HumanPhenoAbnormal 5th finger morphology

ARID1A CASZ1 GLI3 ARID1B

2.70e-0350974HP:0004207
HumanPhenoAbnormality of the humeroradial joint

GLI3 ARID1B

2.94e-036272HP:0100744
HumanPhenoRecurrent upper respiratory tract infections

ARID1A GLI3 ARID1B

3.03e-0323773HP:0002788
HumanPhenoCongenital malformation of the great arteries

ARID1A CASZ1 GLI3 ARID1B

3.11e-0352974HP:0011603
HumanPhenoShort 5th finger

ARID1A ARID1B

3.13e-036472HP:0009237
HumanPhenoFlexion contracture of finger

CASZ1 GLI3 ARID1B

3.14e-0324073HP:0005651
HumanPhenoCamptodactyly (hands)

CASZ1 GLI3 ARID1B

3.14e-0324073HP:0010563
HumanPhenoAbnormality of dental eruption

ARID1A GLI3 ARID1B

3.14e-0324073HP:0006292
HumanPhenoCamptodactyly of toe

CASZ1 GLI3 ARID1B

3.14e-0324073HP:0001836
HumanPhenoJoint contractures involving the joints of the feet

CASZ1 GLI3 ARID1B

3.14e-0324073HP:0100492
HumanPhenoCamptodactyly of finger

CASZ1 GLI3 ARID1B

3.14e-0324073HP:0100490
HumanPhenoFlexion contracture of toe

CASZ1 GLI3 ARID1B

3.14e-0324073HP:0005830
HumanPhenoInterphalangeal joint contracture of finger

CASZ1 GLI3 ARID1B

3.14e-0324073HP:0001220
HumanPhenoAbnormality of the lower urinary tract

ARID1A CASZ1 GLI3 CYP17A1 ARID1B

3.15e-0393775HP:0010936
HumanPhenoAbnormal localization of kidney

ARID1A GLI3 ARID1B

3.18e-0324173HP:0100542
HumanPhenoToe joint contracture

CASZ1 GLI3 ARID1B

3.18e-0324173HP:0034675
HumanPhenoAbnormal skull base morphology

ARID1A GLI3 ARID1B

3.21e-0324273HP:0002693
HumanPhenoAbnormality of circulating cortisol level

GLI3 CYP17A1

3.33e-036672HP:0011731
HumanPhenoAnonychia

ARID1A ARID1B

3.33e-036672HP:0001798
HumanPhenoAplasia/Hypoplasia of the 5th finger

ARID1A ARID1B

3.33e-036672HP:0006262
HumanPhenoAbnormal internal genitalia

ARID1A CASZ1 GLI3 CYP17A1 ARID1B NABP1

3.37e-03149876HP:0000812
HumanPhenoAbnormal brain-evoked potentials

ARID1A GLI3 ARID1B

3.37e-0324673HP:0430106
HumanPhenoAbnormality of circulating glucocorticoid level

GLI3 CYP17A1

3.43e-036772HP:0012111
HumanPhenoExternal genital hypoplasia

CASZ1 GLI3 CYP17A1 ARID1B

3.46e-0354474HP:0003241
HumanPhenoAbnormal nasopharynx morphology

ARID1A GLI3 ARID1B

3.49e-0324973HP:0001739
HumanPhenoAbnormality of the thyroid gland

ARID1A CASZ1 GLI3 ARID1B

3.55e-0354874HP:0000820
MousePhenodecreased circulating glucagon level

FOXA1 NCOA3

1.06e-0420112MP:0002696
MousePhenoabnormal mammary gland development

FOXA1 GLI3 NCOA3

1.12e-04126113MP:0000628
MousePhenoabnormal ear position

GLI3 NCOA3

2.10e-0428112MP:0000023
MousePhenoabnormal skin adnexa development

FOXA1 GLI3 NCOA3

3.06e-04177113MP:0020982
MousePhenoabnormal eye development

ARID1A CASZ1 GLI3 NCOA3

3.80e-04482114MP:0001286
MousePhenoabnormal circulating glucagon level

FOXA1 NCOA3

4.32e-0440112MP:0002695
MousePhenoabnormal mammary gland morphology

FOXA1 GLI3 NCOA3

4.44e-04201113MP:0000627
MousePhenoabnormal apocrine gland morphology

FOXA1 GLI3 NCOA3

4.44e-04201113MP:0013554
MousePhenoabnormal optic cup morphology

ARID1A GLI3

4.76e-0442112MP:0004269
MousePhenoabnormal pluripotent precursor cell morphology

ARID1A GLI3

4.76e-0442112MP:0002399
MousePhenoabnormal branching of the mammary ductal tree

FOXA1 NCOA3

4.76e-0442112MP:0000662
MousePhenodecreased circulating hormone level

FOXA1 CYP17A1 ARID1B NCOA3

6.31e-04551114MP:0014457
MousePhenoabnormal gland development

FOXA1 GLI3 NCOA3

6.83e-04233113MP:0020973
MousePhenoabnormal forebrain size

ARID1A GLI3

7.03e-0451112MP:0012137
MousePhenoskin edema

CASZ1 GLI3

7.59e-0453112MP:0001786
MousePhenodecreased circulating insulin-like growth factor I level

ARID1B NCOA3

1.00e-0361112MP:0004701
MousePhenoabnormal mammary gland duct morphology

FOXA1 NCOA3

1.04e-0362112MP:0009503
MousePhenodecreased hormone level

FOXA1 CYP17A1 ARID1B NCOA3

1.08e-03635114MP:0014455
MousePhenoabnormal hippocampus pyramidal cell layer

GLI3 ARID1B

1.36e-0371112MP:0008284
MousePhenoabnormal circulating insulin-like growth factor I level

ARID1B NCOA3

1.40e-0372112MP:0004700
MousePhenoabnormal mammary gland epithelium morphology

FOXA1 NCOA3

1.47e-0374112MP:0009504
MousePhenoabnormal insulin-like growth factor I level

ARID1B NCOA3

1.51e-0375112MP:0008831
DomainBAF250/Osa

ARID1A ARID1B

3.15e-072112IPR021906
DomainBAF250_C

ARID1A ARID1B

3.15e-072112IPR033388
DomainBAF250_C

ARID1A ARID1B

3.15e-072112PF12031
DomainBRIGHT

ARID1A ARID1B

3.30e-0515112SM00501
Domain-

ARID1A ARID1B

3.30e-05151121.10.150.60
DomainARID

ARID1A ARID1B

3.30e-0515112PF01388
DomainARID_dom

ARID1A ARID1B

3.30e-0515112IPR001606
DomainARID

ARID1A ARID1B

3.30e-0515112PS51011
Domain-

ARID1A ARID1B

7.21e-032221121.25.10.10
DomainARM-like

ARID1A ARID1B

1.05e-02270112IPR011989
PathwayWP_ANDROGEN_RECEPTOR_NETWORK_IN_PROSTATE_CANCER

ARID1A FOXA1 CYP17A1 ARID1B

2.40e-0711084M48043
PathwayWP_TUMOR_SUPPRESSOR_ACTIVITY_OF_SMARCB1

ARID1A GLI3 ARID1B

5.35e-073183M39522
PathwayBIOCARTA_VDR_PATHWAY

ARID1A NCOA3

6.47e-052282MM1370
PathwayWP_KLEEFSTRA_SYNDROME

ARID1A ARID1B

1.14e-042982M48076
PathwayKEGG_MEDICUS_REFERENCE_ADRB3_UCP1_SIGNALING_PATHWAY

ARID1A ARID1B

1.66e-043582M47969
PathwayREACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN

ARID1A ARID1B

1.86e-043782M27797
PathwayREACTOME_REGULATION_OF_MITF_M_DEPENDENT_GENES_INVOLVED_IN_PIGMENTATION

ARID1A ARID1B

2.40e-044282M48237
PathwayPID_HNF3A_PATHWAY

FOXA1 NCOA3

2.63e-044482M285
PathwayREACTOME_RMTS_METHYLATE_HISTONE_ARGININES

ARID1A ARID1B

8.28e-047882M27234
PathwayREACTOME_MITF_M_DEPENDENT_GENE_EXPRESSION

ARID1A ARID1B

1.23e-039582M48268
PathwayREACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS_BY_PIWI_INTERACTING_RNAS_PIRNAS

ARID1A ARID1B

1.28e-039782M48262
PathwayWP_THERMOGENESIS

ARID1A ARID1B

1.58e-0310882M39746
PathwayREACTOME_MITF_M_REGULATED_MELANOCYTE_DEVELOPMENT

ARID1A ARID1B

2.53e-0313782M48232
PathwayREACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS

ARID1A ARID1B

2.71e-0314282M48257
PathwayREACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION

FOXA1 NCOA3

2.98e-0314982M27888
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

ARID1A GLI3 ARID1B NABP1

4.72e-03138784M734
PathwayREACTOME_DEVELOPMENTAL_BIOLOGY

ARID1A FOXA1 ARID1B NCOA3

5.31e-03143284M509
PathwayREACTOME_ESR_MEDIATED_SIGNALING

FOXA1 NCOA3

6.38e-0322082M27794
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1

ARID1A ARID1B

7.37e-0323782M27786
PathwayREACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION

ARID1A ARID1B

8.43e-0325482M27131
PathwayREACTOME_CHROMATIN_MODIFYING_ENZYMES

ARID1A ARID1B

9.62e-0327282M29619
PathwayREACTOME_SIGNALING_BY_NUCLEAR_RECEPTORS

FOXA1 NCOA3

1.13e-0229682M27869
Pubmed

The BAF chromatin complex component SMARCC1 does not mediate GLI transcriptional repression of Hedgehog target genes in limb buds.

ARID1A GLI3 ARID1B

1.97e-09911337805104
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

ARID1A CASZ1 FOXA1 ARID1B NCOA3

4.33e-0922011535785414
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

ARID1A CASZ1 FOXA1 ARID1B NCOA3

1.16e-0826811533640491
Pubmed

Dissecting the role of SWI/SNF component ARID1B in steady-state hematopoiesis.

ARID1A ARID1B

9.09e-08211237611161
Pubmed

Subunits of ARID1 serve as novel biomarkers for the sensitivity to immune checkpoint inhibitors and prognosis of advanced non-small cell lung cancer.

ARID1A ARID1B

9.09e-08211232791957
Pubmed

Dual ARID1A/ARID1B loss leads to rapid carcinogenesis and disruptive redistribution of BAF complexes.

ARID1A ARID1B

9.09e-08211234386776
Pubmed

ARID1B as a Potential Therapeutic Target for ARID1A-Mutant Ovarian Clear Cell Carcinoma.

ARID1A ARID1B

9.09e-08211229890703
Pubmed

Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma.

ARID1A ARID1B

9.09e-08211223202128
Pubmed

ARID1 proteins: from transcriptional and post-translational regulation to carcinogenesis and potential therapeutics.

ARID1A ARID1B

9.09e-08211233890484
Pubmed

SWI/SNF factors required for cellular resistance to DNA damage include ARID1A and ARID1B and show interdependent protein stability.

ARID1A ARID1B

9.09e-08211224788099
Pubmed

Chromatin accessibility underlies synthetic lethality of SWI/SNF subunits in ARID1A-mutant cancers.

ARID1A ARID1B

9.09e-08211228967863
Pubmed

Establishment and characterization of VOA1066 cells: An undifferentiated endometrial carcinoma cell line.

ARID1A ARID1B

9.09e-08211233052929
Pubmed

ARID1B is a specific vulnerability in ARID1A-mutant cancers.

ARID1A ARID1B

9.09e-08211224562383
Pubmed

Concurrent ARID1A and ARID1B inactivation in endometrial and ovarian dedifferentiated carcinomas.

ARID1A ARID1B

9.09e-08211227562491
Pubmed

Identification and Functional Characterization of a Novel Androgen Receptor Coregulator, EAP1.

ARID1A FOXA1 ARID1B

2.31e-074011334585037
Pubmed

Loss of ARID1B and SMARCB1 expression are specific for the diagnosis of dedifferentiated/undifferentiated carcinoma in tumours of the upper gynaecological tract and cervix.

ARID1A ARID1B

2.73e-07311233432679
Pubmed

Dynamics of expression of ARID1A and ARID1B subunits in mouse embryos and in cells during the cell cycle.

ARID1A ARID1B

2.73e-07311221647563
Pubmed

Mutations affecting components of the SWI/SNF complex cause Coffin-Siris syndrome.

ARID1A ARID1B

2.73e-07311222426308
Pubmed

Exome sequencing reveals frequent inactivating mutations in ARID1A, ARID1B, ARID2 and ARID4A in microsatellite unstable colorectal cancer.

ARID1A ARID1B

2.73e-07311224382590
Pubmed

TNPO1-mediated nuclear import of ARID1B promotes tumor growth in ARID1A-deficient gynecologic cancer.

ARID1A ARID1B

2.73e-07311234044070
Pubmed

Genome-Wide Transcriptional Regulation Mediated by Biochemically Distinct SWI/SNF Complexes.

ARID1A ARID1B

2.73e-07311226716708
Pubmed

ARID1A, ARID1B, and ARID2 Mutations Serve as Potential Biomarkers for Immune Checkpoint Blockade in Patients With Non-Small Cell Lung Cancer.

ARID1A ARID1B

2.73e-07311234512623
Pubmed

Gli3 is a negative regulator of Tas1r3-expressing taste cells.

GLI3 POU2F3

5.45e-07411229415007
Pubmed

Undifferentiated Endometrial Carcinomas Show Frequent Loss of Core Switch/Sucrose Nonfermentable Complex Proteins.

ARID1A ARID1B

5.45e-07411228863077
Pubmed

Two related ARID family proteins are alternative subunits of human SWI/SNF complexes.

ARID1A ARID1B

5.45e-07411215170388
Pubmed

Cloning and characterization of hELD/OSA1, a novel BRG1 interacting protein.

ARID1A ARID1B

5.45e-07411211988099
Pubmed

Increased genomic instability and reshaping of tissue microenvironment underlie oncogenic properties of Arid1a mutations.

ARID1A ARID1B

9.09e-07511238489371
Pubmed

Recent advances in understanding chromatin remodeling by Swi/Snf complexes.

ARID1A ARID1B

9.09e-07511212672490
Pubmed

Largest subunits of the human SWI/SNF chromatin-remodeling complex promote transcriptional activation by steroid hormone receptors.

ARID1A ARID1B

9.09e-07511212200431
Pubmed

The p270 (ARID1A/SMARCF1) subunit of mammalian SWI/SNF-related complexes is essential for normal cell cycle arrest.

ARID1A ARID1B

1.36e-06611216230384
Pubmed

Numerous BAF complex genes are mutated in Coffin-Siris syndrome.

ARID1A ARID1B

1.36e-06611225081545
Pubmed

Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping.

ARID1A ARID1B NCOA3

1.77e-067811328611094
Pubmed

Reversible disruption of mSWI/SNF (BAF) complexes by the SS18-SSX oncogenic fusion in synovial sarcoma.

ARID1A ARID1B

1.91e-06711223540691
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

ARID1A ARID1B NCOA3

2.13e-068311328794006
Pubmed

Polymorphisms in steroid hormone pathway genes and mammographic density.

CYP17A1 NCOA3

2.54e-06811212602902
Pubmed

Coffin-Siris Syndrome

ARID1A ARID1B

3.27e-06911223556151
Pubmed

Mammalian SWI/SNF--a subunit BAF250/ARID1 is an E3 ubiquitin ligase that targets histone H2B.

ARID1A ARID1B

3.27e-06911220086098
Pubmed

Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia.

ARID1B NCOA3

3.27e-06911219176441
Pubmed

Nomenclature of the ARID family of DNA-binding proteins.

ARID1A ARID1B

4.09e-061011215922553
Pubmed

ARID1a-DNA interactions are required for promoter occupancy by SWI/SNF.

ARID1A ARID1B

4.09e-061011223129809
Pubmed

Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway.

ARID1B NCOA3

4.09e-061011216751102
Pubmed

Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner.

ARID1A ARID1B

4.09e-061011212665591
Pubmed

Genome-wide impact of the BRG1 SWI/SNF chromatin remodeler on the transforming growth factor beta transcriptional program.

ARID1A NCOA3

4.99e-061111218003620
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

ARID1A CASZ1 ARID1B NCOA3

5.23e-0639811435016035
Pubmed

Arid1a regulates bladder urothelium formation and maintenance.

ARID1A ARID1B

5.99e-061211235283102
Pubmed

SYT associates with human SNF/SWI complexes and the C-terminal region of its fusion partner SSX1 targets histones.

ARID1A ARID1B

5.99e-061211211734557
Pubmed

An improved smaller biotin ligase for BioID proximity labeling.

TDRD7 ARID1A ARID1B

6.98e-0612311326912792
Pubmed

Foxa1 and Foxa2 positively and negatively regulate Shh signalling to specify ventral midbrain progenitor identity.

FOXA1 GLI3

7.08e-061311221093585
Pubmed

Separation and Quantification of Some Alkaloids from Fumaria parviflora by Capillary Isotachophoresis1.

ARID1A ARID1B

7.08e-061311217340523
Pubmed

Blood pressure and hypertension are associated with 7 loci in the Japanese population.

CASZ1 CYP17A1

7.08e-061311220479155
Pubmed

Mammalian SWI/SNF complexes promote MyoD-mediated muscle differentiation.

ARID1A ARID1B

9.53e-061511211175787
Pubmed

Distinct mammalian SWI/SNF chromatin remodeling complexes with opposing roles in cell-cycle control.

ARID1A ARID1B

9.53e-061511217255939
Pubmed

Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways.

ARID1A ARID1B

9.53e-061511223785148
Pubmed

Regulation of dendritic development by neuron-specific chromatin remodeling complexes.

ARID1A ARID1B

9.53e-061511217920018
Pubmed

The murine SNF5/INI1 chromatin remodeling factor is essential for embryonic development and tumor suppression.

ARID1A ARID1B

9.53e-061511211263494
Pubmed

Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.

CASZ1 CYP17A1

1.09e-051611221572416
Pubmed

Overactivation of hedgehog signaling alters development of the ovarian vasculature in mice.

GLI3 CYP17A1

1.23e-051711222402963
Pubmed

Identification of a polymorphic, neuron-specific chromatin remodeling complex.

ARID1A ARID1B

1.23e-051711212368262
Pubmed

The human SWI/SNF-B chromatin-remodeling complex is related to yeast rsc and localizes at kinetochores of mitotic chromosomes.

ARID1A ARID1B

1.23e-051711211078522
Pubmed

Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort.

FOXA1 NCOA3

1.23e-051711219183483
Pubmed

Polymorphisms in genes of the steroid hormone biosynthesis and metabolism pathways and endometrial cancer risk.

CYP17A1 NCOA3

1.23e-051711220381444
Pubmed

BAF complexes facilitate decatenation of DNA by topoisomerase IIα.

ARID1A ARID1B

1.39e-051811223698369
Pubmed

SPOP promotes ATF2 ubiquitination and degradation to suppress prostate cancer progression.

GLI3 NCOA3

1.39e-051811229996942
Pubmed

Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes.

ARID1A ARID1B

1.55e-051911212110891
Pubmed

Mammalian SWI/SNF complexes facilitate DNA double-strand break repair by promoting gamma-H2AX induction.

ARID1A ARID1B

1.55e-051911216932743
Pubmed

Genome-wide association study of blood pressure and hypertension.

CASZ1 CYP17A1

1.55e-051911219430479
Pubmed

Diencephalic Size Is Restricted by a Novel Interplay Between GCN5 Acetyltransferase Activity and Retinoic Acid Signaling.

FOXA1 GLI3

1.72e-052011228154153
Pubmed

The negative regulator of Gli, Suppressor of fused (Sufu), interacts with SAP18, Galectin3 and other nuclear proteins.

GLI3 NCOA3

1.72e-052011214611647
Pubmed

Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.

CASZ1 CYP17A1

1.90e-052111225249183
Pubmed

Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells.

FOXA1 NCOA3

2.29e-052311219737349
Pubmed

Diversity and specialization of mammalian SWI/SNF complexes.

ARID1A ARID1B

2.29e-05231128804307
Pubmed

FET family fusion oncoproteins target the SWI/SNF chromatin remodeling complex.

ARID1A ARID1B

2.29e-052311230962207
Pubmed

Cardiomyocyte proliferation is suppressed by ARID1A-mediated YAP inhibition during cardiac maturation.

ARID1A ARID1B

2.50e-052411237543677
Pubmed

GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation.

GLI3 CYP17A1

2.50e-052411232497091
Pubmed

The SWI/SNF chromatin-remodeling factor stimulates repair by human excision nuclease in the mononucleosome core particle.

ARID1A ARID1B

2.50e-052411212215535
Pubmed

SWI/SNF chromatin remodeling and cancer.

ARID1A ARID1B

2.50e-052411211790558
Pubmed

Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits.

ARID1A ARID1B

2.50e-052411210078207
Pubmed

Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF.

ARID1A ARID1B

2.94e-052611210778858
Pubmed

Glioma tumor suppressor candidate region gene 1 (GLTSCR1) and its paralog GLTSCR1-like form SWI/SNF chromatin remodeling subcomplexes.

ARID1A ARID1B

3.18e-052711229374058
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

ARID1A CASZ1 ARID1B NCOA3

3.34e-0563811431182584
Pubmed

Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation.

ARID1A ARID1B

3.42e-052811230037996
Pubmed

REST repression of neuronal genes requires components of the hSWI.SNF complex.

ARID1A ARID1B

3.42e-052811212192000
Pubmed

An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency.

ARID1A ARID1B

3.68e-052911219279220
Pubmed

RNF138 inhibits late inflammatory gene transcription through degradation of SMARCC1 of the SWI/SNF complex.

ARID1A ARID1B

3.68e-052911236800290
Pubmed

Mammalian SWI/SNF collaborates with a polycomb-associated protein to regulate male germline transcription in the mouse.

ARID1A ARID1B

3.94e-053011231043422
Pubmed

Human transcription factor protein interaction networks.

ARID1A FOXA1 GLI3 ARID1B NCOA3

4.37e-05142911535140242
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

CASZ1 GLI3 NCOA3

4.71e-0523311337704626
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

ARID1A FOXA1 GLI3 POU2F3

5.04e-0570911422988430
Pubmed

The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation.

ARID1A ARID1B

5.38e-053511232504627
Pubmed

Analysis of the SWI/SNF chromatin-remodeling complex during early heart development and BAF250a repression cardiac gene transcription during P19 cell differentiation.

ARID1A ARID1B

6.02e-053711224335282
Pubmed

Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice.

GLI3 CYP17A1

6.02e-053711226697723
Pubmed

Intrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT-mTORC1 activation.

GLI3 NCOA3

7.05e-054011228805822
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ARID1A GLI3 POU2F3 NCOA3

8.38e-0580811420412781
Pubmed

Congenital Diaphragmatic Hernia Overview

ARID1A ARID1B

9.34e-054611220301533
Pubmed

Regulation of the CUL3 Ubiquitin Ligase by a Calcium-Dependent Co-adaptor.

ARID1A ARID1B

1.10e-045011227716508
Pubmed

A census of human transcription factors: function, expression and evolution.

FOXA1 GLI3 POU2F3 NCOA3

1.32e-0490811419274049
Pubmed

A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene.

GLI3 ARID1B SPTY2D1

1.33e-0433111319490893
Pubmed

The SWI/SNF chromatin remodeling factor DPF3 regulates metastasis of ccRCC by modulating TGF-β signaling.

ARID1A ARID1B

1.34e-045511235945219
Pubmed

Interaction network of human early embryonic transcription factors.

ARID1A ARID1B NCOA3

1.58e-0435111338297188
Pubmed

A lentiviral functional proteomics approach identifies chromatin remodeling complexes important for the induction of pluripotency.

ARID1A ARID1B

1.65e-046111220305087
InteractionSOX7 interactions

ARID1A CASZ1 ARID1B NCOA3

8.22e-0882114int:SOX7
InteractionNFIB interactions

ARID1A FOXA1 ARID1B NCOA3

7.50e-07142114int:NFIB
InteractionGATA3 interactions

ARID1A FOXA1 ARID1B NCOA3

2.25e-06187114int:GATA3
InteractionNFIA interactions

ARID1A FOXA1 ARID1B NCOA3

2.30e-06188114int:NFIA
InteractionNFIC interactions

ARID1A FOXA1 ARID1B NCOA3

3.57e-06210114int:NFIC
InteractionAR interactions

ARID1A CASZ1 FOXA1 GLI3 ARID1B NCOA3

5.23e-06992116int:AR
InteractionGCM1 interactions

ARID1A ARID1B NCOA3

5.95e-0668113int:GCM1
InteractionETV4 interactions

ARID1A ARID1B NCOA3

6.21e-0669113int:ETV4
InteractionASF1A interactions

ARID1A CASZ1 ARID1B SPTY2D1

7.01e-06249114int:ASF1A
InteractionCREBBP interactions

ARID1A GLI3 ARID1B POU2F3 NCOA3

9.08e-06599115int:CREBBP
InteractionIRF4 interactions

ARID1A ARID1B NCOA3

1.17e-0585113int:IRF4
InteractionFOXI1 interactions

ARID1A ARID1B NCOA3

1.48e-0592113int:FOXI1
InteractionSOX10 interactions

ARID1A ARID1B NCOA3

1.48e-0592113int:SOX10
InteractionSOX17 interactions

ARID1A ARID1B NCOA3

1.63e-0595113int:SOX17
InteractionSOX9 interactions

ARID1A ARID1B NCOA3

1.73e-0597113int:SOX9
InteractionPAX8 interactions

ARID1A ARID1B NCOA3

2.60e-05111113int:PAX8
InteractionTBR1 interactions

ARID1A ARID1B NCOA3

2.74e-05113113int:TBR1
InteractionSMARCC2 interactions

ARID1A FOXA1 ARID1B NCOA3

2.77e-05353114int:SMARCC2
InteractionTBXT interactions

ARID1A ARID1B NCOA3

2.96e-05116113int:TBXT
InteractionETS1 interactions

ARID1A ARID1B NCOA3

3.36e-05121113int:ETS1
InteractionTLE3 interactions

ARID1A FOXA1 ARID1B NCOA3

3.55e-05376114int:TLE3
InteractionPAX7 interactions

ARID1A ARID1B NCOA3

3.62e-05124113int:PAX7
InteractionSMAD2 interactions

ARID1A GLI3 ARID1B NCOA3

3.89e-05385114int:SMAD2
InteractionPAX9 interactions

ARID1A ARID1B NCOA3

4.17e-05130113int:PAX9
InteractionTEX13B interactions

ARID1A ARID1B

5.12e-0520112int:TEX13B
InteractionSOX15 interactions

ARID1A ARID1B NCOA3

5.31e-05141113int:SOX15
InteractionSMAD3 interactions

ARID1A GLI3 ARID1B NCOA3

6.96e-05447114int:SMAD3
InteractionKLF4 interactions

ARID1A ARID1B NCOA3

7.73e-05160113int:KLF4
InteractionEGR2 interactions

ARID1A ARID1B NCOA3

9.42e-05171113int:EGR2
InteractionTLX1 interactions

ARID1A ARID1B NCOA3

1.01e-04175113int:TLX1
InteractionARID1B interactions

ARID1A ARID1B NCOA3

1.04e-04177113int:ARID1B
InteractionALG13 interactions

ARID1A ARID1B NCOA3

1.15e-04183113int:ALG13
InteractionHNF1B interactions

ARID1A ARID1B NCOA3

1.29e-04190113int:HNF1B
InteractionMYOD1 interactions

ARID1A ARID1B NCOA3

1.37e-04194113int:MYOD1
InteractionKLF5 interactions

ARID1A ARID1B NCOA3

1.39e-04195113int:KLF5
InteractionGATA2 interactions

ARID1A ARID1B NCOA3

1.48e-04199113int:GATA2
InteractionFEV interactions

ARID1A ARID1B NCOA3

1.57e-04203113int:FEV
InteractionE2F5 interactions

ARID1A ARID1B

1.69e-0436112int:E2F5
InteractionERG interactions

ARID1A ARID1B NCOA3

2.07e-04223113int:ERG
InteractionNCOA3 interactions

FOXA1 ARID1B NCOA3

2.09e-04224113int:NCOA3
InteractionNFIX interactions

ARID1A FOXA1 ARID1B

2.18e-04227113int:NFIX
InteractionTFF1 interactions

FOXA1 NCOA3

2.20e-0441112int:TFF1
InteractionNR5A2 interactions

FOXA1 NCOA3

2.20e-0441112int:NR5A2
InteractionRARB interactions

ARID1A NCOA3

2.77e-0446112int:RARB
InteractionCRX interactions

ARID1A ARID1B NCOA3

3.03e-04254113int:CRX
InteractionHNF4A interactions

ARID1A ARID1B NCOA3

3.82e-04275113int:HNF4A
InteractionTPRX2 interactions

ARID1A ARID1B

4.10e-0456112int:TPRX2
InteractionSMARCE1 interactions

ARID1A ARID1B NCOA3

4.33e-04287113int:SMARCE1
InteractionRARG interactions

ARID1A NCOA3

4.40e-0458112int:RARG
InteractionTLX3 interactions

ARID1A ARID1B NCOA3

4.51e-04291113int:TLX3
InteractionFLI1 interactions

ARID1A ARID1B

5.03e-0462112int:FLI1
InteractionSP7 interactions

ARID1A ARID1B NCOA3

5.13e-04304113int:SP7
InteractionSAP18 interactions

ARID1A GLI3 NCOA3

5.18e-04305113int:SAP18
InteractionFOS interactions

ARID1A ARID1B NCOA3

5.53e-04312113int:FOS
InteractionBICRA interactions

ARID1A ARID1B

5.87e-0467112int:BICRA
InteractionSMG7 interactions

ARID1A ARID1B NCOA3

5.90e-04319113int:SMG7
InteractionDCTN6 interactions

FOXA1 NCOA3

6.05e-0468112int:DCTN6
InteractionHAPSTR1 interactions

ARID1A FOXA1 ARID1B SPTY2D1

7.44e-04829114int:HAPSTR1
InteractionSS18L2 interactions

ARID1A ARID1B

7.55e-0476112int:SS18L2
InteractionPAX6 interactions

ARID1A ARID1B NCOA3

8.80e-04366113int:PAX6
InteractionIRF1 interactions

ARID1A ARID1B

9.00e-0483112int:IRF1
InteractionSTK11IP interactions

ARID1A ARID1B

9.00e-0483112int:STK11IP
InteractionPGR interactions

ARID1A NCOA3

9.21e-0484112int:PGR
InteractionPAX2 interactions

ARID1B NCOA3

9.43e-0485112int:PAX2
InteractionGSC interactions

ARID1B NCOA3

9.88e-0487112int:GSC
InteractionSS18 interactions

ARID1A ARID1B

1.01e-0388112int:SS18
InteractionSMARCC1 interactions

ARID1A ARID1B NCOA3

1.01e-03384113int:SMARCC1
InteractionMKRN2 interactions

TDRD7 CASZ1 GLI3

1.02e-03385113int:MKRN2
InteractionMYH6 interactions

FOXA1 SPTY2D1

1.15e-0394112int:MYH6
InteractionDPF3 interactions

ARID1A ARID1B

1.18e-0395112int:DPF3
InteractionDPF1 interactions

ARID1A ARID1B

1.18e-0395112int:DPF1
InteractionBCL7B interactions

ARID1A ARID1B

1.18e-0395112int:BCL7B
InteractionGATA4 interactions

ARID1A FOXA1 SPTY2D1

1.23e-03411113int:GATA4
InteractionSS18L1 interactions

ARID1A ARID1B

1.25e-0398112int:SS18L1
InteractionSNIP1 interactions

ARID1A ARID1B SPTY2D1

1.28e-03417113int:SNIP1
InteractionNUP35 interactions

ARID1A ARID1B NCOA3

1.35e-03424113int:NUP35
InteractionNR3C1 interactions

ARID1A CASZ1 ARID1B NCOA3

1.36e-03974114int:NR3C1
InteractionLHX1 interactions

ARID1A ARID1B

1.38e-03103112int:LHX1
InteractionSUFU interactions

GLI3 NCOA3

1.46e-03106112int:SUFU
InteractionSMARCD3 interactions

ARID1A ARID1B

1.49e-03107112int:SMARCD3
InteractionINTS6 interactions

FOXA1 NABP1

1.57e-03110112int:INTS6
InteractionTRIM33 interactions

FOXA1 ARID1B NCOA3

1.63e-03453113int:TRIM33
InteractionBCL7C interactions

ARID1A ARID1B

1.72e-03115112int:BCL7C
InteractionSMARCA4 interactions

ARID1A GLI3 ARID1B

1.72e-03462113int:SMARCA4
InteractionBRD9 interactions

ARID1A ARID1B

1.78e-03117112int:BRD9
InteractionDDIT3 interactions

ARID1A ARID1B

1.87e-03120112int:DDIT3
InteractionEYA2 interactions

ARID1A ARID1B

1.90e-03121112int:EYA2
InteractionMLLT1 interactions

ARID1A ARID1B

1.96e-03123112int:MLLT1
InteractionBCL7A interactions

ARID1A ARID1B

1.96e-03123112int:BCL7A
InteractionRNF138 interactions

ARID1A ARID1B

2.02e-03125112int:RNF138
InteractionYAP1 interactions

ARID1A FOXA1 ARID1B POU2F3

2.10e-031095114int:YAP1
InteractionNOL8 interactions

CASZ1 FOXA1

2.12e-03128112int:NOL8
InteractionBUB1 interactions

TDRD7 ARID1A

2.42e-03137112int:BUB1
InteractionPHF10 interactions

ARID1A ARID1B

2.49e-03139112int:PHF10
InteractionSMAD4 interactions

GLI3 ARID1B NCOA3

2.55e-03530113int:SMAD4
InteractionTP53BP1 interactions

ARID1A ARID1B NCOA3

2.59e-03533113int:TP53BP1
InteractionTLX2 interactions

ARID1A ARID1B

2.60e-03142112int:TLX2
InteractionTRPS1 interactions

FOXA1 NCOA3

2.64e-03143112int:TRPS1
CytobandEnsembl 112 genes in cytogenetic band chr1p36

ARID1A CASZ1

1.11e-02681112chr1p36
GeneFamilyAT-rich interaction domain containing

ARID1A ARID1B

2.31e-051592418
CoexpressionRIZ_ERYTHROID_DIFFERENTIATION_HEMGN

FOXA1 POU2F3

5.18e-0526112M7999
CoexpressionRIZ_ERYTHROID_DIFFERENTIATION_HEMGN

FOXA1 POU2F3

5.18e-0526112MM510
CoexpressionMARSON_BOUND_BY_FOXP3_UNSTIMULATED

ARID1A POU2F3 NCOA3 NABP1 SPTY2D1

8.52e-051239115M1743
CoexpressionMARSON_BOUND_BY_FOXP3_UNSTIMULATED

ARID1A POU2F3 NCOA3 NABP1 SPTY2D1

9.83e-051277115MM1032
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

ARID1A ARID1B NCOA3

1.12e-05186113de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

ARID1A ARID1B NCOA3

1.12e-051861130b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellLA-14._Fibroblast_III|World / Chamber and Cluster_Paper

GLI3 ARID1B NABP1

1.27e-05194113803fa83ceada17c38ca9f933b888f7e7b0b90761
ToppCellTCGA-Testes-Primary_Tumor-Testicular_Germ_Cell_Tumor-Non-Seminoma-_Embryonal_Carcinoma,_Immature_Teratoma,_Mature_Teratoma,_Yolk_Sac_Tumor|TCGA-Testes / Sample_Type by Project: Shred V9

GLI3 POU2F3

5.04e-04138112f7c40156c34d2d910bbda5ba07540ad0f6f22981
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

ARID1B NABP1

5.72e-0414711294998bc40f5c08295cfe3bdcbe43f13b1e564b3d
ToppCellTCGA-Breast|World / Sample_Type by Project: Shred V9

FOXA1 GLI3

5.95e-0415011208686ba1acac5c58667bf62e2af84c691d6bbdfb
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Dendritic|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TDRD7 CYP17A1

6.19e-04153112a35149a0c8b4ec9ad27cc4b3d34fba3b8714a6a2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Dendritic-conventional_dendritic_cell|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TDRD7 CYP17A1

6.19e-04153112ee6f4770c6e35d59bdeec5b0ecb10119fa8c3ca5
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TDRD7 CYP17A1

6.19e-0415311290cd6efda83c0b4b80eae2c90e7ff45dfd936dc2
ToppCell18-Airway-Epithelial-Goblet-like_secretory|Airway / Age, Tissue, Lineage and Cell class

FOXA1 POU2F3

6.19e-0415311214a60220e169ce642771636de982a7b02e5b2608
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_C-8|TCGA-Thymus / Sample_Type by Project: Shred V9

FOXA1 POU2F3

6.35e-0415511200eef9f93a753a1fe1ab5fd8dae026e7be556cde
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_C|TCGA-Thymus / Sample_Type by Project: Shred V9

FOXA1 POU2F3

7.02e-041631122dac87d15051151ccf193760ddd8b82534c3f922
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related-Tuft|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CASZ1 POU2F3

7.19e-0416511234fd00be2b28716c871ad9fb356de84a299a0c01
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

ARID1A ARID1B

7.28e-0416611232d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCelldroplet-Lung-30m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NCOA3 NABP1

7.28e-041661121a3a15d1fc76bb91d832cdc6e3da0a6140b94b75
ToppCelldroplet-Lung-18m-Epithelial-airway_epithelial-club_cell-club_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXA1 GLI3

7.99e-04174112103594eeb600eb5bc9cbf09a65b286b3a3a18cdc
ToppCelldroplet-Lung-18m-Epithelial-airway_epithelial-club_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXA1 GLI3

7.99e-0417411246838b4bb9b4d8ce5e1c608a700e7f393bc52658
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CASZ1 FOXA1

8.18e-041761123bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCellfacs-Spleen-nan-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP17A1 NABP1

8.55e-04180112407fd8f61a757626e082b6e2eefd3a33276e6b71
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

ARID1B NABP1

8.64e-04181112f2315414e714ac86211546a935660c4be6e85f1b
ToppCellcellseq2-Immune-Hematopoietic-Granulocytic-Neutrophil|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CYP17A1 NABP1

8.74e-041821121932d77491d6d46278f01fd70eb469ef1b356619
ToppCellcellseq2-Immune-Hematopoietic-Granulocytic|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CYP17A1 NABP1

8.83e-04183112cfbf8539104cef9ca830ad4f6bb278746f7078f7
ToppCellcellseq2-Immune-Hematopoietic|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CYP17A1 NABP1

8.83e-04183112324ec4374b552da7ce03809945b3a0798342d4ba
ToppCellPCW_05-06-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TDRD7 FOXA1

8.83e-04183112c5b10571599dc26476170b54b53f09c23e6b3117
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CASZ1 FOXA1

9.03e-04185112eb78614c4acf8d2ce7874d7e51e16997b76127ef
ToppCelldroplet-Skin|droplet / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASZ1 POU2F3

9.03e-04185112657fd191ed160f8620d57b33820ec7222806f289
ToppCellsaliva-Severe-critical_progression_d28-40|saliva / Compartment, severity and other cell annotations on 10x 3' data (130k)

FOXA1 NABP1

9.12e-041861120095560ca776b01aa473ad4d6015ed78fc93ff51
ToppCellfacs-Trachea-nan-24m-Epithelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASZ1 FOXA1

9.12e-041861126c06163d7315f1c71b15fe76f2e696bf3fa73b67
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CASZ1 FOXA1

9.12e-0418611237b93ebd64ebbd08193a746e5bc9b350c2570733
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____podocyte-3|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXA1 POU2F3

9.12e-0418611229c79b5a29907d4f3f87ad2ca04840c0f15b7d4e
ToppCellfacs-Trachea-nan-24m-Epithelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASZ1 FOXA1

9.12e-0418611278e3b00eb347d1aa197671e31be9b0c6e4235760
ToppCellsaliva-Mild-Moderate_progression_d12-25-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TDRD7 FOXA1

9.22e-0418711243ef900b76f3c38bd8ce9858201124130c743d56
ToppCelldroplet-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CASZ1 FOXA1

9.22e-04187112796046ff066a9c3847faa9bf1f8beccd956c01f7
ToppCelldroplet-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CASZ1 FOXA1

9.22e-04187112380c3e0bc73b266718893a3b3ca207ce5fd31883
ToppCelldroplet-Trachea-nan-3m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASZ1 FOXA1

9.22e-041871125b3c3c6421efd25c740ae121968b5520bbdc07b2
ToppCellsaliva-Mild-Moderate_progression_d12-25-Epithelial-Epithelial,_Airway-secretory_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TDRD7 FOXA1

9.22e-041871126e5c38425b6b1d4774f8dcea7e146f1eab785c3e
ToppCellfacs-Trachea-nan-3m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASZ1 FOXA1

9.22e-04187112fe9fc21192ede2eea61f419d20ccda254569d0a6
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CASZ1 FOXA1

9.32e-04188112137ed9958044fab7a13648affb469585d1c48cf6
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CASZ1 FOXA1

9.32e-041881128ffb5394f7b00ea483a5fe4df894d22fda935e5c
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

ARID1B NABP1

9.32e-04188112ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CASZ1 ARID1B

9.32e-04188112d8decd9b5967873ca8320c2f9f07365f163c777f
ToppCelldroplet-Trachea-nan-3m-Epithelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASZ1 FOXA1

9.52e-04190112434de72dde09644efbddcaa643a4a3eaf5f643bf
ToppCelldroplet-Trachea-3m-Epithelial-airway_epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CASZ1 FOXA1

9.52e-0419011201e7747547ea1f3049a11a1717565ba71dd52bdc
ToppCelldroplet-Trachea-nan-3m-Epithelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASZ1 FOXA1

9.52e-04190112e647f9a2dcf7f2dffef53c45bbe171416518fd59
ToppCelldroplet-Trachea-3m-Epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CASZ1 FOXA1

9.52e-041901120114cf48612d78c3ada4d8a05850501fef6892c5
ToppCelldroplet-Bladder-nan-24m|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXA1 NABP1

9.52e-04190112725657faf90b8ef0a286a3fd64ed18ab600aa2df
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CASZ1 ARID1B

9.52e-041901120724665ac8238f2383c3a929d89abf4a48ec2420
ToppCellfacs-Trachea-24m-Epithelial-airway_epithelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CASZ1 FOXA1

9.52e-04190112576c45a30a4808b47433bc6c2c41396135556c40
ToppCellfacs-Skin|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASZ1 POU2F3

9.62e-04191112ae524103331fa53fa82888dbb567fc36abcee7e0
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CASZ1 ARID1B

9.72e-04192112446c61c0d6ba89c619efe87ee495951299953981
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CASZ1 ARID1B

9.82e-04193112bbea475d2c4c7b29674ff302529f8f83dd666dcb
ToppCellLA-14._Fibroblast_III|LA / Chamber and Cluster_Paper

ARID1B NABP1

9.82e-041931127426c291bac59e539c427bcaae18abc7d397d44e
ToppCellfacs-Trachea-24m-Epithelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CASZ1 FOXA1

9.82e-04193112ec49a83b24371579d4ad46aad91c25115aa226f9
ToppCelldroplet-Bladder-nan-3m-Epithelial-bladder_urothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASZ1 FOXA1

9.82e-04193112ee91a796d0f6d4cee7a93a525689e716fdceeda5
ToppCelldroplet-Bladder-nan-3m-Epithelial-basal_bladder_epithelial_cell_(Krt5+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASZ1 FOXA1

9.82e-04193112268925bfe85fb94a93a4ff8fe078d692df888140
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

ARID1A SPTY2D1

9.82e-04193112abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ARID1B NCOA3

9.92e-04194112ff661419b697aef51a53fdeac8d37d870d65f491
ToppCellfacs-Trachea-nan-3m-Epithelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASZ1 FOXA1

9.92e-041941123701ca87c6dc9ccd7b4146e56371546174d26c36
ToppCellfacs-Trachea-nan-3m-Epithelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASZ1 FOXA1

9.92e-0419411265f9bf126be26114c2c3f4c46d48318986212a92
ToppCellB_cells-ISG-high_B_cells|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

TDRD7 CASZ1

1.00e-03195112b64d9e1a8834401b4dc501566546647754ae21fc
ToppCelldroplet-Mammary_Gland-nan-18m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASZ1 FOXA1

1.00e-0319511218220efbd2d6ce6aa7501744fe430b6b46f2fc30
ToppCelldroplet-Bladder-nan-3m-Epithelial-luminal_bladder_epithelial_cell_(umbrella_cell)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASZ1 FOXA1

1.00e-03195112d6e2a5a15bea16de5f7ff09318c67d46ea923203
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CASZ1 NCOA3

1.00e-031951120c49d22c348aec6d8a1a976e7c88d0a3b48a4244
ToppCellMild-CD4+_T_activated|World / Disease group and Cell class

TDRD7 NABP1

1.01e-03196112417b4fc2e4388f34c410576131b02936f93e46b6
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CASZ1 ARID1B

1.02e-03197112e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors|1_mon / Sample Type, Dataset, Time_group, and Cell type.

ARID1A GLI3

1.04e-03199112358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCell(08)_Brush+PNEC|World / shred by cell type by condition

GLI3 POU2F3

1.04e-03199112f2e33cb569c25fc2732722cac295647e9bd8738f
ToppCellmild-B_naive|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ARID1B NCOA3

1.05e-03200112222789b897e2a683bbfd1d00b6fd8705015d90df
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-squamous_epithelial_cell-Epi-Squamous|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CASZ1 FOXA1

1.05e-0320011203051d2190244208905e1611019d4b8fd200bae0
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CASZ1 FOXA1

1.05e-0320011297f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellmild-B_intermediate|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ARID1B NCOA3

1.05e-03200112fe815824e9e4be3f3db73610e3814a7fd533da65
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CASZ1 FOXA1

1.05e-03200112ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-squamous_epithelial_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CASZ1 FOXA1

1.05e-032001121c02a7f4047d1d2208cc522c6bb4a4989d7845bb
DrugAcetohexamide [968-81-0]; Up 200; 12.4uM; PC3; HT_HG-U133A

TDRD7 ARID1A CYP17A1

9.27e-051921131829_UP
DrugKaempferol [520-18-3]; Down 200; 14uM; PC3; HT_HG-U133A

ARID1A CYP17A1 NCOA3

9.41e-051931135839_DN
DrugNorgestrel-(-)-D [797-63-7]; Down 200; 12.8uM; MCF7; HT_HG-U133A

ARID1A CASZ1 GLI3

1.00e-041971133406_DN
DrugSTOCK1N-35874; Down 200; 14uM; PC3; HT_HG-U133A

CASZ1 GLI3 NCOA3

1.00e-041971136561_DN
DrugImipenem [74431-23-5]; Up 200; 13.4uM; MCF7; HT_HG-U133A

ARID1A CYP17A1 POU2F3

1.00e-041971132873_UP
DrugMesoridazine besylate [32672-69-8]; Up 200; 7.4uM; MCF7; HT_HG-U133A

ARID1A CYP17A1 POU2F3

1.02e-041981132874_UP
DrugPridinol methanesulfonate salt [6856-31-1]; Up 200; 10.2uM; HL60; HT_HG-U133A

CASZ1 GLI3 NABP1

1.02e-041981132715_UP
DrugHomochlorcyclizine dihydrochloride [1982-36-1]; Down 200; 10.4uM; HL60; HT_HG-U133A

CASZ1 CYP17A1 NCOA3

1.03e-041991132386_DN
DrugPiperacillin sodium salt [59703-84-3]; Down 200; 7.4uM; MCF7; HT_HG-U133A

ARID1A CYP17A1 POU2F3

1.03e-041991133845_DN
Drugprofenofos

ARID1A CYP17A1

1.32e-0436112ctd:C024273
DrugAndrostenedione

CYP17A1 NCOA3

2.08e-0445112ctd:D000735
Drugtallow

FOXA1 CYP17A1 NABP1

2.54e-04270113ctd:C013698
Drugtris(chloroethyl)phosphate

CYP17A1 NCOA3

3.11e-0455112ctd:C031324
DrugAC1O4QIW

ARID1A POU2F3

3.58e-0459112CID006398478
DrugAndrogens

GLI3 CYP17A1

4.21e-0464112ctd:D000728
DrugBortezomib

FOXA1 NCOA3 NABP1 SPTY2D1

4.89e-04838114ctd:D000069286
Drug2,3,4,7,8-pentachlorodibenzofuran

CYP17A1 NCOA3

5.78e-0475112ctd:C038890
Drug3,3',4,5'-tetrahydroxystilbene

CYP17A1 NCOA3

6.73e-0481112ctd:C041525
Drugtris(2-butoxyethyl) phosphate

CYP17A1 NCOA3

7.24e-0484112ctd:C013320
Drughydroxyflutamide

CYP17A1 NCOA3

1.09e-03103112CID000091649
DrugEstrone

CYP17A1 NCOA3

1.28e-03112112ctd:D004970
DrugNSC98537

FOXA1 CYP17A1 NCOA3

1.30e-03473113CID000005410
Drugfulvestrant

ARID1A CYP17A1 NCOA3

1.39e-03484113ctd:C070081
Drug8-MOP

CYP17A1 POU2F3

1.42e-03118112CID000004114
Drug4,4'-hexafluorisopropylidene diphenol

CYP17A1 NCOA3

2.05e-03142112ctd:C583074
DrugAsbestos, Crocidolite

ARID1A ARID1B NCOA3 NABP1

2.13e-031241114ctd:D017638
DrugDiclofenac

TDRD7 FOXA1 NCOA3

2.22e-03570113ctd:D004008
DrugMethyl-1 (S-methylphosphoryl-3) imidazolium

CYP17A1 POU2F3

2.31e-03151112CID000051213
DrugMercury

ARID1A POU2F3 NCOA3

2.38e-03584113ctd:D008628
Drugdiphenylamine-2-carboxylate

FOXA1 CYP17A1

2.72e-03164112CID000004386
Drugirinotecan HCl; Down 200; 100uM; PC3; HT_HG-U133A

GLI3 NCOA3

2.95e-031711127535_DN
DrugLY 294002; Up 200; 10uM; MCF7; HT_HG-U133A_EA

GLI3 CYP17A1

3.02e-031731121016_UP
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

ARID1A GLI3

3.05e-031741126493_DN
DrugMetaproterenol sulfate, orciprenaline sulfate [5874-97-5]; Up 200; 7.6uM; PC3; HT_HG-U133A

POU2F3 NCOA3

3.23e-031791124248_UP
DrugCamptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; PC3; HT_HG-U133A

ARID1A GLI3

3.26e-031801124541_DN
Drugmono-(2-ethylhexyl)phthalate

FOXA1 GLI3 CYP17A1

3.33e-03658113ctd:C016599
DrugDoxorubicin hydrochloride [25316-40-9]; Down 200; 6.8uM; PC3; HT_HG-U133A

ARID1A GLI3

3.41e-031841124610_DN
DrugTribenoside [10310-32-4]; Up 200; 8.4uM; HL60; HT_HG-U133A

CASZ1 NABP1

3.41e-031841122946_UP
Drug1ga8

ARID1A CYP17A1

3.41e-03184112CID000445801
Drug2,4,4'-trichlorobiphenyl

ARID1A CASZ1 CYP17A1 NABP1

3.41e-031411114ctd:C081766
Drugtyrphostin AG-825; Down 200; 25.2uM; MCF7; HT_HG-U133A_EA

ARID1A NCOA3

3.44e-031851121114_DN
Drugretinoic acid; Up 200; 1uM; MCF7; HT_HG-U133A

GLI3 CYP17A1

3.44e-031851126931_UP
DiseaseBreast adenocarcinoma

ARID1A FOXA1 ARID1B

4.08e-0741113C0858252
DiseaseNeoplasm of uncertain or unknown behavior of breast

ARID1A FOXA1 ARID1B

4.08e-0741113C0496956
DiseaseBreast Carcinoma

ARID1A FOXA1 CYP17A1 ARID1B NCOA3

8.35e-07538115C0678222
DiseaseMENTAL RETARDATION, AUTOSOMAL DOMINANT 12

ARID1A ARID1B

1.26e-065112C3281201
DiseaseProstatic Neoplasms

ARID1A CASZ1 FOXA1 CYP17A1 NCOA3

1.62e-06616115C0033578
DiseaseMalignant neoplasm of prostate

ARID1A CASZ1 FOXA1 CYP17A1 NCOA3

1.62e-06616115C0376358
Diseaseneuroblastoma (is_implicated_in)

ARID1A ARID1B

5.68e-0610112DOID:769 (is_implicated_in)
Diseaseesophagus adenocarcinoma (is_marker_for)

ARID1A FOXA1

8.32e-0612112DOID:4914 (is_marker_for)
DiseaseCoffin-Siris syndrome

ARID1A ARID1B

9.83e-0613112C0265338
Diseasebreast cancer (is_implicated_in)

ARID1A FOXA1 CYP17A1

2.06e-05150113DOID:1612 (is_implicated_in)
DiseaseMalignant neoplasm of breast

ARID1A FOXA1 CYP17A1 ARID1B NCOA3

2.43e-051074115C0006142
Diseaseunipolar depression, systolic blood pressure

CASZ1 CYP17A1

7.04e-0534112EFO_0003761, EFO_0006335
DiseaseNeuroblastoma

ARID1A ARID1B

1.35e-0447112C0027819
DiseaseMale sterility

TDRD7 CYP17A1

1.41e-0448112C0917731
DiseaseMale infertility

TDRD7 CYP17A1

1.41e-0448112C0021364
DiseaseSubfertility, Male

TDRD7 CYP17A1

1.41e-0448112C0848676
Diseasestomach cancer (is_implicated_in)

ARID1A FOXA1

3.18e-0472112DOID:10534 (is_implicated_in)
Diseasemean arterial pressure, alcohol drinking

CASZ1 GLI3

5.89e-0498112EFO_0004329, EFO_0006340
Diseaselow density lipoprotein cholesterol measurement, alcohol consumption measurement

ARID1A SPTY2D1

6.01e-0499112EFO_0004611, EFO_0007878
Diseaselow density lipoprotein cholesterol measurement, alcohol drinking

ARID1A SPTY2D1

6.38e-04102112EFO_0004329, EFO_0004611
Diseasemean arterial pressure

CASZ1 CYP17A1 POU2F3

7.17e-04499113EFO_0006340
DiseaseLiver carcinoma

ARID1A CYP17A1 ARID1B

7.51e-04507113C2239176
DiseaseAdenocarcinoma

ARID1A NCOA3

8.23e-04116112C0001418
DiseaseCarcinoma, Granular Cell

ARID1A NCOA3

8.23e-04116112C0205644
DiseaseAdenocarcinoma, Tubular

ARID1A NCOA3

8.23e-04116112C0205645
DiseaseAdenocarcinoma, Oxyphilic

ARID1A NCOA3

8.23e-04116112C0205642
DiseaseCarcinoma, Cribriform

ARID1A NCOA3

8.23e-04116112C0205643
DiseaseAdenocarcinoma, Basal Cell

ARID1A NCOA3

8.23e-04116112C0205641
DiseaseMammary Neoplasms, Human

FOXA1 CYP17A1 NCOA3

8.31e-04525113C1257931
DiseaseMammary Carcinoma, Human

FOXA1 CYP17A1 NCOA3

8.31e-04525113C4704874
DiseaseMammary Neoplasms

FOXA1 CYP17A1 NCOA3

8.40e-04527113C1458155
Diseaselung non-small cell carcinoma (is_implicated_in)

ARID1A ARID1B

1.18e-03139112DOID:3908 (is_implicated_in)
Diseasestomach cancer (is_marker_for)

ARID1A FOXA1

1.23e-03142112DOID:10534 (is_marker_for)
Diseasecolorectal cancer (is_marker_for)

ARID1A FOXA1

1.50e-03157112DOID:9256 (is_marker_for)
Diseasesmoking status measurement, diastolic blood pressure

CASZ1 ARID1B

1.54e-03159112EFO_0006336, EFO_0006527
Diseaseapolipoprotein B measurement

ARID1A CASZ1 SPTY2D1

1.63e-03663113EFO_0004615
Diseaselung non-small cell carcinoma (is_marker_for)

ARID1A FOXA1

1.73e-03169112DOID:3908 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
SLMNKMSQGNPGLGS

CASZ1

956

Q86V15
GPGMGISANNQMHGQ

ARID1B

941

Q8NFD5
NQSPSGAMSNLGMGQ

ARID1B

1381

Q8NFD5
GGTMANNSAGMAASP

ARID1A

951

O14497
PNESAGSMVNGMQNQ

GLI3

1301

P10071
SQGPAMMSGNQMSGL

POU2F3

66

Q9UKI9
SGMGAMGAQQAASMN

FOXA1

111

P55317
LMQAKMNSDNGNAGP

CYP17A1

266

P05093
MNSNMGTGTFGPVGN

NABP1

136

Q96AH0
SSVGGMSMSPNQGLQ

NCOA3

396

Q9Y6Q9
GADSPNSKNGNMPMS

TDRD7

856

Q8NHU6
NSKNGNMPMSGNTGE

TDRD7

861

Q8NHU6
SSNGQMNGMKPPLSG

SPTY2D1

551

Q68D10