Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionamino acid sensor activity

SAR1B SAR1A

1.67e-052822GO:0140785
GeneOntologyMolecularFunctionryanodine-sensitive calcium-release channel activity

RYR2 RYR3

9.94e-054822GO:0005219
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR2 RYR3

2.47e-046822GO:0048763
GeneOntologyMolecularFunctionextracellularly glycine-gated ion channel activity

GLRB GLRA3

2.47e-046822GO:0016933
GeneOntologyMolecularFunctionextracellularly glycine-gated chloride channel activity

GLRB GLRA3

2.47e-046822GO:0016934
GeneOntologyMolecularFunctionferrous iron binding

ALKBH1 UROD HEPH

2.50e-0430823GO:0008198
GeneOntologyMolecularFunctioninhibitory extracellular ligand-gated monoatomic ion channel activity

GLRB GLRA3

4.59e-048822GO:0005237
GeneOntologyMolecularFunctionphosphatidylinositol-3,5-bisphosphate 3-phosphatase activity

MTMR6 MTM1

8.94e-0411822GO:0052629
GeneOntologyMolecularFunctionhistone H4K12 acetyltransferase activity

MEAF6 KAT2A

1.07e-0312822GO:0043997
GeneOntologyMolecularFunctionmolecular sensor activity

SAR1B NOX4 SAR1A

1.14e-0350823GO:0140299
GeneOntologyMolecularFunctionphosphatidylinositol-3-phosphate phosphatase activity

MTMR6 MTM1

1.47e-0314822GO:0004438
GeneOntologyMolecularFunctionglycine binding

GLRB GLRA3

1.47e-0314822GO:0016594
GeneOntologyMolecularFunctionphosphatidylinositol monophosphate phosphatase activity

MTMR6 MTM1

1.69e-0315822GO:0052744
GeneOntologyMolecularFunctionhistone H3 acetyltransferase activity

MEAF6 KAT2A

1.69e-0315822GO:0010484
GeneOntologyMolecularFunctionlyase activity

ALKBH1 POLG UROD CA10 ADCY5

1.81e-03212825GO:0016829
GeneOntologyMolecularFunctionphosphatidylinositol-3,5-bisphosphate phosphatase activity

MTMR6 MTM1

1.93e-0316822GO:0106018
GeneOntologyCellularComponentglycine-gated chloride channel complex

GLRB GLRA3

1.60e-052842GO:0016935
GeneOntologyCellularComponentsarcoplasmic reticulum

AGL NOX4 SAR1A RYR2 RYR3

2.80e-0588845GO:0016529
GeneOntologyCellularComponentsarcoplasm

AGL NOX4 SAR1A RYR2 RYR3

9.67e-05114845GO:0016528
GeneOntologyCellularComponentcalcium channel complex

CACNA2D2 CATSPERG RYR2 RYR3

2.14e-0473844GO:0034704
DomainSmall_GTPase_SAR1

SAR1B SAR1A

2.00e-052842IPR006687
DomainSAR1

SAR1B SAR1A

2.00e-052842PS51422
DomainRyanrecept_TM4-6

RYR2 RYR3

5.98e-053842IPR009460
DomainRyR

RYR2 RYR3

5.98e-053842PF02026
DomainRyanodine_rcpt

RYR2 RYR3

5.98e-053842IPR003032
DomainRR_TM4-6

RYR2 RYR3

5.98e-053842PF06459
DomainRyan_recept

RYR2 RYR3

5.98e-053842IPR013333
DomainRIH_assoc

RYR2 RYR3

2.96e-046842PF08454
DomainRIH_assoc-dom

RYR2 RYR3

2.96e-046842IPR013662
DomainRIH_dom

RYR2 RYR3

2.96e-046842IPR000699
DomainIns145_P3_rcpt

RYR2 RYR3

2.96e-046842IPR014821
DomainRyanodine_recept-rel

RYR2 RYR3

2.96e-046842IPR015925
DomainEPTP

LGI3 LGI1

2.96e-046842PF03736
Domain-

RYR2 RYR3

2.96e-0468421.25.10.30
DomainEPTP

LGI3 LGI1

2.96e-046842IPR005492
DomainRYDR_ITPR

RYR2 RYR3

2.96e-046842PF01365
DomainIns145_P3_rec

RYR2 RYR3

2.96e-046842PF08709
DomainLRRCT

LGI3 TLR5 LGI1

3.96e-0432843PF01463
DomainEAR

LGI3 LGI1

4.14e-047842IPR009039
DomainEAR

LGI3 LGI1

4.14e-047842PS50912
DomainMIR

RYR2 RYR3

8.79e-0410842PS50919
DomainMIR

RYR2 RYR3

8.79e-0410842PF02815
DomainMIR

RYR2 RYR3

8.79e-0410842SM00472
DomainMIR_motif

RYR2 RYR3

8.79e-0410842IPR016093
DomainRap_GAP

GARNL3 SIPA1L1

8.79e-0410842PF02145
DomainRap_GAP_dom

GARNL3 SIPA1L1

1.07e-0311842IPR000331
DomainRAPGAP

GARNL3 SIPA1L1

1.07e-0311842PS50085
DomainGlycoside_hydrolase_SF

GLB1L AGL MANEA

1.75e-0353843IPR017853
DomainMyotubularin-like_Pase_dom

MTMR6 MTM1

1.76e-0314842IPR010569
DomainPPASE_MYOTUBULARIN

MTMR6 MTM1

1.76e-0314842PS51339
DomainMyotubularin_fam

MTMR6 MTM1

1.76e-0314842IPR030564
DomainMyotub-related

MTMR6 MTM1

1.76e-0314842PF06602
Domain-

MTMR6 RASA2 MTM1 ARHGAP12 PLEKHA5 PREX2 PLCE1

1.90e-033918472.30.29.30
DomainGal_mutarotase_SF_dom

LGI3 LGI1

2.60e-0317842IPR011013
DomainPH_dom-like

MTMR6 RASA2 MTM1 ARHGAP12 PLEKHA5 PREX2 PLCE1

3.06e-03426847IPR011993
DomainTyr_Pase_AS

MTMR6 MTM1 DUSP11

4.35e-0373843IPR016130
DomainRASGEF

RASGRP2 PLCE1

6.06e-0326842PS00720
DomainTYR_PHOSPHATASE_1

MTMR6 MTM1 DUSP11

6.87e-0386843PS00383
DomainTYR_PHOSPHATASE_2

MTMR6 MTM1 DUSP11

7.09e-0387843PS50056
DomainTYR_PHOSPHATASE_dom

MTMR6 MTM1 DUSP11

7.09e-0387843IPR000387
Pubmed

Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease.

RYR2 RYR3

5.90e-06285221531043
Pubmed

Genetic variation of the human glycine receptor subunit genes GLRA3 and GLRB and susceptibility to idiopathic generalized epilepsies.

GLRB GLRA3

5.90e-06285211496371
Pubmed

Modulation of calcium signalling by dominant negative splice variant of ryanodine receptor subtype 3 in native smooth muscle cells.

RYR2 RYR3

5.90e-06285216678258
Pubmed

Phosphatidylinositol-5-phosphate activation and conserved substrate specificity of the myotubularin phosphatidylinositol 3-phosphatases.

MTMR6 MTM1

5.90e-06285212646134
Pubmed

Functional overlap between the mammalian Sar1a and Sar1b paralogs in vivo.

SAR1B SAR1A

5.90e-06285238687799
Pubmed

Tissue-specific alternative splicing of mouse brain type ryanodine receptor/calcium release channel mRNA.

RYR2 RYR3

5.90e-0628528898078
Pubmed

The mouse sino-atrial node expresses both the type 2 and type 3 Ca(2+) release channels/ryanodine receptors.

RYR2 RYR3

5.90e-06285214550562
Pubmed

Silencing of mammalian Sar1 isoforms reveals COPII-independent protein sorting and transport.

SAR1B SAR1A

5.90e-06285223433038
Pubmed

The endoplasmic reticulum coat protein II transport machinery coordinates cellular lipid secretion and cholesterol biosynthesis.

SAR1B SAR1A

5.90e-06285224338480
Pubmed

Modulation of membrane rigidity by the human vesicle trafficking proteins Sar1A and Sar1B.

SAR1B SAR1A

5.90e-06285222974979
Pubmed

Decreased expression of ryanodine receptors alters calcium-induced calcium release mechanism in mdx duodenal myocytes.

RYR2 RYR3

5.90e-06285214985349
Pubmed

Molecular analysis of SAR1-related cDNAs from a mouse pituitary cell line.

SAR1B SAR1A

5.90e-0628528262187
Pubmed

SAR1B senses leucine levels to regulate mTORC1 signalling.

SAR1B SAR1A

5.90e-06285234290409
Pubmed

Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.

RYR2 RYR3

1.77e-05385218403125
Pubmed

Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.

RYR2 RYR3

1.77e-05385218434746
Pubmed

Small GTPases SAR1A and SAR1B regulate the trafficking of the cardiac sodium channel Nav1.5.

SAR1B SAR1A

1.77e-05385230251687
Pubmed

Control of Neuronal Ryanodine Receptor-Mediated Calcium Signaling by Calsenilin.

RYR2 RYR3

1.77e-05385229730765
Pubmed

SPRY domains in ryanodine receptors (Ca(2+)-release channels).

RYR2 RYR3

1.77e-0538529204703
Pubmed

The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.

RYR2 RYR3

1.77e-0538527876312
Pubmed

Ryanodine receptors are expressed in epidermal keratinocytes and associated with keratinocyte differentiation and epidermal permeability barrier homeostasis.

RYR2 RYR3

1.77e-05385221881589
Pubmed

Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors).

RYR2 RYR3

1.77e-05385212213830
Pubmed

Expression of the ryanodine receptor type 3 calcium release channel during development and differentiation of mammalian skeletal muscle cells.

RYR2 RYR3

1.77e-0538529242641
Pubmed

Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.

RYR2 RYR3

1.77e-05385222948152
Pubmed

Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.

RYR2 RYR3

1.77e-05385210788707
Pubmed

RYR2 proteins contribute to the formation of Ca(2+) sparks in smooth muscle.

RYR2 RYR3

1.77e-05385215024040
Pubmed

Calcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells.

RYR2 RYR3

1.77e-05385225239916
Pubmed

Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.

RYR2 RYR3

1.77e-0538527621815
Pubmed

A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice.

RYR2 RYR3

1.77e-05385218643873
Pubmed

Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2).

RYR2 RYR3

1.77e-05385211159936
Pubmed

Nonsense in the testis: multiple roles for nonsense-mediated decay revealed in male reproduction.

PLEKHA5 TDRD6

1.77e-05385228444146
Pubmed

Small sequence variations between two mammalian paralogs of the small GTPase SAR1 underlie functional differences in coat protein complex II assembly.

SAR1B SAR1A

1.77e-05385232358066
Pubmed

Mitochondrial respiratory chain disorders in the Old Order Amish population.

NDUFAF2 POLG

1.77e-05385227344355
Pubmed

Molecular identification of the ryanodine receptor pore-forming segment.

RYR2 RYR3

1.77e-05385210473538
Pubmed

Chromosomal localization of murine ryanodine receptor genes RYR1, RYR2, and RYR3 by in situ hybridization.

RYR2 RYR3

1.77e-0538527959768
Pubmed

The organization of proteins in the human red blood cell membrane. A review.

RYR2 RYR3

1.77e-0538524600883
Pubmed

Regulation of mouse egg activation: presence of ryanodine receptors and effects of microinjected ryanodine and cyclic ADP ribose on uninseminated and inseminated eggs.

RYR2 RYR3

1.77e-0538527635066
Pubmed

Splice-specific roles of glycine receptor alpha3 in the hippocampus.

GLRB GLRA3

1.77e-05385219723286
Pubmed

The FYVE domain of Smad Anchor for Receptor Activation (SARA) is required to prevent skin carcinogenesis, but not in mouse development.

SAR1B SAR1A

3.53e-05485225170969
Pubmed

A glutathione deficit alters dopamine modulation of L-type calcium channels via D2 and ryanodine receptors in neurons.

RYR2 RYR3

3.53e-05485218206662
Pubmed

Expression and mRNA splicing of glycine receptor subunits and gephyrin during neuronal differentiation of P19 cells in vitro, studied by RT-PCR and immunocytochemistry.

GLRB GLRA3

3.53e-0548529051263
Pubmed

Activation of glycine receptor phase-shifts the circadian rhythm in neuronal activity in the mouse suprachiasmatic nucleus.

GLRB GLRA3

3.53e-05485221486797
Pubmed

Ryanodine receptor calcium release channels: lessons from structure-function studies.

RYR2 RYR3

3.53e-05485223413940
Pubmed

Requirement for the ryanodine receptor type 3 for efficient contraction in neonatal skeletal muscles.

RYR2 RYR3

3.53e-0548529384575
Pubmed

Identification of myotubularin as the lipid phosphatase catalytic subunit associated with the 3-phosphatase adapter protein, 3-PAP.

MTMR6 MTM1

3.53e-05485212847286
Pubmed

Regional distribution of the leucine-rich glioma inactivated (LGI) gene family transcripts in the adult mouse brain.

LGI3 LGI1

3.53e-05485219833108
Pubmed

Alpha subunit-dependent glycine receptor clustering and regulation of synaptic receptor numbers.

GLRB GLRA3

3.53e-05485228883437
Pubmed

Partial cloning and differential expression of ryanodine receptor/calcium-release channel genes in human tissues including the hippocampus and cerebellum.

RYR2 RYR3

3.53e-0548529607712
Pubmed

Conserved and divergent functions of Nfix in skeletal muscle development during vertebrate evolution.

RYR2 RYR3

3.53e-05485223482488
Pubmed

NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure.

GLRB PLEKHA5 RASGRP2

3.95e-052785323359859
Pubmed

Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases.

RYR2 RYR3

5.87e-05585233060591
Pubmed

The flagellin-TLR5-Nox4 axis promotes the migration of smooth muscle cells in atherosclerosis.

TLR5 NOX4

5.87e-05585231292433
Pubmed

Developmental regulation of glycine receptors at efferent synapses of the murine cochlea.

GLRB GLRA3

5.87e-05585221850450
Pubmed

Presenilins regulate calcium homeostasis and presynaptic function via ryanodine receptors in hippocampal neurons.

RYR2 RYR3

5.87e-05585223918386
Pubmed

Crucial role of phospholipase C epsilon in skin inflammation induced by tumor-promoting phorbol ester.

RASGRP2 PLCE1

5.87e-05585218172297
Pubmed

Oligodendrocyte-derived LGI3 and its receptor ADAM23 organize juxtaparanodal Kv1 channel clustering for short-term synaptic plasticity.

LGI3 LGI1

5.87e-05585238194969
Pubmed

Native glycine receptor subtypes and their physiological roles.

GLRB GLRA3

5.87e-05585218721822
Pubmed

Protein kinase C-epsilon regulates local calcium signaling in airway smooth muscle cells.

RYR2 RYR3

5.87e-05585219011160
Pubmed

Membrane depolarization causes a direct activation of G protein-coupled receptors leading to local Ca2+ release in smooth muscle.

RYR2 RYR3

8.80e-05685219549818
Pubmed

Rectification of muscle and nerve deficits in paralyzed ryanodine receptor type 1 mutant embryos.

RYR2 RYR3

8.80e-05685226025922
Pubmed

Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.

RYR2 RYR3

8.80e-05685223463619
Pubmed

Phospholipase Cε hydrolyzes perinuclear phosphatidylinositol 4-phosphate to regulate cardiac hypertrophy.

RYR2 PLCE1

8.80e-05685223540699
Pubmed

A common protein interaction domain links two recently identified epilepsy genes.

LGI3 LGI1

8.80e-05685212095917
Pubmed

FKBP12.6 and cADPR regulation of Ca2+ release in smooth muscle cells.

RYR2 RYR3

8.80e-05685214592808
Pubmed

A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.

RYR2 RYR3

8.80e-05685220519450
Pubmed

Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.

RYR2 RYR3

8.80e-05685225966694
Pubmed

HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization.

RYR2 RYR3

8.80e-05685219009018
Pubmed

The novel EPTP repeat defines a superfamily of proteins implicated in epileptic disorders.

LGI3 LGI1

8.80e-05685212217514
Pubmed

Mutations in a Sar1 GTPase of COPII vesicles are associated with lipid absorption disorders.

SAR1B SAR1A

8.80e-05685212692552
Pubmed

IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.

RYR2 RYR3

8.80e-05685216844763
Pubmed

The claw paw mutation reveals a role for Lgi4 in peripheral nerve development.

LGI3 LGI1

1.23e-04785216341215
Pubmed

Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.

RYR2 RYR3

1.23e-04785211860456
Pubmed

Human immunodeficiency virus-1 Tat activates calpain proteases via the ryanodine receptor to enhance surface dopamine transporter levels and increase transporter-specific uptake and Vmax.

RYR2 RYR3

1.23e-04785220962236
Pubmed

Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.

RYR2 RYR3

1.64e-04885219033399
Pubmed

Sequential docking, molecular differentiation, and positioning of T-Tubule/SR junctions in developing mouse skeletal muscle.

RYR2 RYR3

1.64e-04885211784029
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

H1-10 ATP6V1H TENT4B CACNA2D2 DYNC2H1 MARS1 CSNK2A2 NOL6 NIPSNAP1 WDR46 TDRD6 SAR1A

1.77e-041425851230948266
Pubmed

Characterization of the myotubularin dual specificity phosphatase gene family from yeast to human.

MTMR6 MTM1

2.62e-04108529736772
Pubmed

AAV-mediated intramuscular delivery of myotubularin corrects the myotubular myopathy phenotype in targeted murine muscle and suggests a function in plasma membrane homeostasis.

MTM1 RYR2

2.62e-041085218434328
Pubmed

Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.

MEAF6 NDUFAF2 SIPA1L1 TTLL4 SAR1B PLEKHA5 ATP11A

3.48e-0453685715840001
Pubmed

Exchangeable gene trap using the Cre/mutated lox system.

MEAF6 NDUFAF2 SIPA1L1 TTLL4 SAR1B PLEKHA5 ATP11A

3.55e-0453885710512203
Pubmed

New molecular components supporting ryanodine receptor-mediated Ca(2+) release: roles of junctophilin and TRIC channel in embryonic cardiomyocytes.

RYR2 RYR3

3.83e-041285219095005
Pubmed

Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

ABRA MTMR6 GARNL3 MANEA ODAD4 USP37 CA10 SAR1A

5.03e-0475085811230166
Pubmed

The protein kinase KIS impacts gene expression during development and fear conditioning in adult mice.

GLRB GLRA3

5.27e-041485222937132
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

ZC3H7A RINT1 ZNF789 ARHGAP12 NOL6 KRT20 ATP11A KAT2A SPAG17 RYR2 SLC6A14

7.66e-041442851135575683
Pubmed

Human variation in alcohol response is influenced by variation in neuronal signaling genes.

GLRB SIX3 RYR3 PLCE1

8.38e-0417185420201926
Pubmed

Genome-wide association study identifies genetic risk underlying primary rhegmatogenous retinal detachment.

GOLPH3L CTSS

8.80e-041885223585552
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

CCDC59 RASA2 DYNC2H1 CSNK2A2 NOL6 SAR1A RYR2

9.70e-0463885731182584
Pubmed

Association studies of 23 positional/functional candidate genes on chromosome 10 in late-onset Alzheimer's disease.

SAR1A PLCE1

9.83e-041985217373700
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

ZC3H7A NRDE2 CCDC59 TENT4B MARS1 CSNK2A2 SIPA1L1 NOL6 GPRC5C KAT2A DUSP11

1.04e-031497851131527615
Pubmed

Genome-wide RNAi screen identifies the Parkinson disease GWAS risk locus SREBF1 as a regulator of mitophagy.

CSNK2A2 KAT2A

1.09e-032085224912190
Pubmed

RUNX1 maintains the identity of the fetal ovary through an interplay with FOXL2.

PLA2R1 RYR2

1.20e-032185231712577
Pubmed

PRDM16 determines specification of ventricular cardiomyocytes by suppressing alternative cell fates.

CACNA2D2 RYR3

1.20e-032185239304345
Pubmed

Interaction proteomics of canonical Caspr2 (CNTNAP2) reveals the presence of two Caspr2 isoforms with overlapping interactomes.

LGI3 LGI1

1.20e-032185225707359
Pubmed

Large-scale screen for genes involved in gonad development.

PTOV1 NIPSNAP1 PLEKHA5

1.25e-038685311044607
Pubmed

Stage-dependent and locus-specific role of histone demethylase Jumonji D3 (JMJD3) in the embryonic stages of lung development.

KIRREL3 MARCHF4

1.32e-032285225079229
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

NRDE2 MTMR6 RASA2 MARS1 CSNK2A2 POLG SIPA1L1 TTLL4 ATP11A

1.33e-03108485911544199
Pubmed

The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.

CSNK2A2 TDRD6 RYR2 DUSP11

1.41e-0319785420811636
Pubmed

The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.

H1-10 TENT4B CSNK2A2 NOL6 WDR46

1.68e-0334985525665578
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

ZC3H7A H1-10 ALKBH1 RASA2 MARS1 NOL6 NIPSNAP1 WDR46 PLEKHA5 NCCRP1

1.70e-031353851029467282
Pubmed

Identification of 15 loci influencing height in a Korean population.

KRT20 SPAG17

1.99e-032785219893584
Pubmed

Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia.

KRT20 NOX4

1.99e-032785228167773
CytobandEnsembl 112 genes in cytogenetic band chr2q35

GLB1L TTLL4 USP37 MARCHF4

1.01e-04129854chr2q35
Cytoband2q35

GLB1L USP37 MARCHF4

4.38e-04798532q35
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR2 RYR3

3.46e-053622287
GeneFamilyGlycine receptors

GLRB GLRA3

1.15e-045622868
GeneFamilyMyotubularins|Phosphoinositide phosphatases

MTMR6 MTM1

1.18e-0315622903
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABRA ANGPT2 TTLL4 ARHGAP12 MARCHF4 HEPH

1.15e-061778568abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M LOXHD1 SPAG17 RYR2 RYR3 PLCE1

1.44e-061848562cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M LOXHD1 SPAG17 RYR2 RYR3 PLCE1

1.44e-06184856ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M LOXHD1 SPAG17 RYR2 RYR3 PLCE1

1.44e-061848562b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellhuman_hepatoblastoma-Endothelial_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

LOXHD1 ANGPT2 RBMS3 ESAM NOX4 PREX2

1.85e-06192856e09f609fed033a25baacaf4a07bbbae1076da366
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

A2M ADAMTS2 RBMS3 COL27A1 PREX2 RYR2

1.90e-06193856b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M ANGPT2 ESAM GPRC5C RASGRP2 PLCE1

1.96e-061948563b9ada901dfe7a5cc4861a883d3268c53b11e5b6
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M PLA2R1 LOXHD1 ADAMTS2 RBMS3 COL27A1

2.02e-0619585644d7bef5f59c2c2bad1392ee6aabdaa5d7f531d9
ToppCell356C-Epithelial_cells-Epithelial-A_(AT2)|356C / Donor, Lineage, Cell class and subclass (all cells)

CACNA2D2 LGI3 ESAM GPRC5C ATP11A SLC6A14

2.08e-0619685693a5d9b8bcff7d07596ef1f4f2b74f043835fc69
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M ANGPT2 ESAM GPRC5C RASGRP2 PLCE1

2.08e-06196856624f700daea48d9bad4cc554f4776bd809ae1e54
ToppCell356C-Epithelial_cells-Epithelial-A_(AT2)-|356C / Donor, Lineage, Cell class and subclass (all cells)

CACNA2D2 LGI3 ESAM GPRC5C ATP11A SLC6A14

2.08e-061968564715f19f844e7244fc4bc446cba7c8088c600fc3
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

A2M MMP25 ANGPT2 ESAM NOX4 PREX2

2.21e-0619885672e8b9cccb7b0a2ea9d415218fff4fa2f09728f4
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

A2M MMP25 ANGPT2 ESAM NOX4 PREX2

2.27e-061998569c40b3ee39860e9d8edafd007daec11abdd95435
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MMP25 ANGPT2 RBMS3 ESAM NOX4 PREX2

2.27e-06199856d95d78b2ebc9a20532466e4d4be579b4faf6776f
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MMP25 ANGPT2 RBMS3 ESAM NOX4 PREX2

2.27e-06199856cdcfca94baba66e213cc3ffb0cfb4c75d6ab44ec
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

A2M MMP25 ANGPT2 ESAM NOX4 PREX2

2.27e-0619985672b34bce8157abe389e95cd3ed8ba578dce0cbf6
ToppCellTracheal-10x3prime_v2-Stromal-Pericyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

A2M ESAM ADCY5 PREX2 RYR2 PLCE1

2.34e-06200856600d56257b1b0cda8ed2fd0db92c6551711f7d6d
ToppCelldroplet-Limb_Muscle-nan-18m-Myeloid-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS2 GLB1L COL27A1 TLR5 CTSS

1.48e-0516285571d7849108a1b59beff40e46000172c45a2f5439
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

A2M PLA2R1 ADAMTS2 FRRS1L RYR3

1.81e-0516985516c52a0f6d96ecc1832922fce9b39691849f0d73
ToppCelldroplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLEKHA5 BARX2 CLNK NCCRP1 PLCE1

1.87e-05170855bf589c4297ccc90e5f51e3d0fcc229548af4fcef
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Enterocyte_(Proximal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT20 ATP11A CTSS HEPH SLC6A14

1.92e-051718555d0d6c1ff610a703ae0b834a12823c5ff9012932
ToppCelldroplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLEKHA5 BARX2 CLNK NCCRP1 PLCE1

2.03e-0517385570c0c13febd28b395fb3171ec8d7fbbc6c9d4eb7
ToppCell3'_v3-bone_marrow-Lymphocytic_B-GC_B_(I)|bone_marrow / Manually curated celltypes from each tissue

ZGRF1 TTLL4 GLRA3 PLEKHA5 ZNF440

2.03e-0517385567f0f0bf88eab69987b71d96b864ed2b14975adb
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

A2M ADCY5 PREX2 RYR2 PLCE1

2.33e-05178855185b44700f06ec58b3c09c80520502166c965fd6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLA2R1 KIRREL3 CA10 RYR3 PLCE1

2.39e-051798557394e77e665bf16d3733df91bb12907be460ab44
ToppCelldroplet-Liver-nan-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2R1 ZGRF1 ESAM ATP11A PREX2

2.52e-05181855fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLA2R1 GLRA3 CA10 RYR3 PLCE1

2.52e-051818555bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLA2R1 GLRA3 CA10 RYR3 PLCE1

2.52e-051818558e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCellCOVID-19-Fibroblasts-Pericytes|COVID-19 / group, cell type (main and fine annotations)

RBMS3 ADCY5 PREX2 RYR2 PLCE1

2.80e-051858554905adaeeffd353e089578e5ea614437dbe794e6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PLA2R1 KIRREL3 CA10 RYR3 PLCE1

2.80e-05185855b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

H1-10 ADAMTS2 SPAG17 CTSS RYR2

2.87e-0518685523b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellfacs-Lung-18m-Mesenchymal-myofibroblast-myofibroblast_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ANGPT2 RBMS3 NOX4 GPRC5C ADCY5

2.87e-0518685526458ff8cad5577de4306cffa0ca69eb26940e0d
ToppCellfacs-Lung-18m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ANGPT2 RBMS3 NOX4 GPRC5C ADCY5

2.87e-05186855a71397efc68d2916ddc373d92cfd07be58033e1c
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GARNL3 GLB1L TTLL4 TLR5 SIX3

2.95e-05187855f5a202d5f8eb57b57d80815ce98774e04c387383
ToppCellIPF-Epithelial-ATII|Epithelial / Disease state, Lineage and Cell class

CACNA2D2 LGI3 ESAM ATP11A SLC6A14

3.02e-051888555f5fad2773e421760e67dbace23fd1f847a2e1e0
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A2M ANGPT2 ADCY5 RYR2 PLCE1

3.10e-051898557fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A2M ANGPT2 ADCY5 RYR2 PLCE1

3.10e-0518985506b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCellAT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

CACNA2D2 COL27A1 LGI3 ESAM ATP11A

3.10e-051898552d32f09efa982ae458568f6b1cd06bb5078d42a3
ToppCellMesenchymal-pericyte_cell|World / Lineage, Cell type, age group and donor

ANGPT2 ADCY5 PREX2 RYR2 PLCE1

3.10e-05189855d7ed96add29f219183c802895fbff519b627f635
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RBMS3 ADCY5 PREX2 RYR2 PLCE1

3.18e-051908554eb92aef1ee868f4537483d19014d947b7684612
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_1|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

CACNA2D2 FRRS1L SIX3 RYR2 LGI1

3.18e-051908556e92c78799f34b31d098854503c796edb0dc7f80
ToppCellhuman_hepatoblastoma-Endothelial_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

LOXHD1 ANGPT2 RBMS3 NOX4 PREX2

3.18e-051908558d6ef93d69e96cd6921816d152bea3b0710cf147
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MTMR6 CACNA2D2 RBMS3 ARHGAP12 PLCE1

3.18e-0519085539ab890104b4264c68a968f920f4ccd84f0bc681
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RBMS3 ADCY5 PREX2 RYR2 PLCE1

3.18e-051908557be4341e2909101d756f14031c21e705eb45e69a
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIRREL3 GPRC5C BARX2 SIX3 NCCRP1

3.26e-05191855e96184aee03175fd9f1da11fa2b89d95ba58b817
ToppCellControl-Stromal-SMC|Stromal / Disease state, Lineage and Cell class

ANGPT2 ESAM GPRC5C ADCY5 RASGRP2

3.26e-051918552da83c493e60ad0278848957645277d76737a188
ToppCellCOVID-19-Myeloid-DC1|Myeloid / Condition, Lineage and Cell class

GARNL3 ESAM PLEKHA5 CLNK PREX2

3.26e-051918554be3c6287965fe3a2f109d26f68bdc2fa393f99b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M LOXHD1 ADAMTS2 RBMS3 COL27A1

3.34e-051928559093a9e94a25682d109a7f6edc256a25a61103a0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M LOXHD1 ADAMTS2 RBMS3 COL27A1

3.34e-051928559ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCellIPF-Stromal-SMC|Stromal / Disease state, Lineage and Cell class

ANGPT2 ESAM GPRC5C ADCY5 RASGRP2

3.34e-051928559b06c7336624ef21f8e5393725b56038a8028e57
ToppCellControl-Myeloid-cMonocyte|Control / Disease state, Lineage and Cell class

TENT4B ADAMTS2 SIPA1L1 FAM157C CTSS

3.34e-05192855ad04c9c4bdebf94615cee1904ca48197e62c923b
ToppCellnormal_Lung-Epithelial_cells-AT2|normal_Lung / Location, Cell class and cell subclass

CACNA2D2 LGI3 GPRC5C ATP11A SLC6A14

3.42e-0519385580ad1bdc50ecb8a50362f718248441cae20904a6
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

A2M ADAMTS2 RBMS3 PREX2 RYR2

3.42e-0519385599525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

A2M RBMS3 NOX4 PLEKHA5 RYR2

3.42e-05193855e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANGPT2 RBMS3 GPRC5C RASGRP2 PLCE1

3.42e-051938557766f495f2f945802ef9a5b994cd00bb64d0dfe3
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CACNA2D2 DYNC2H1 ATP11A ODAD4 SPAG17

3.42e-05193855bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCellmetastatic_Brain-Fibroblasts-Pericytes|metastatic_Brain / Location, Cell class and cell subclass

A2M ANGPT2 ESAM HEPH PLCE1

3.51e-05194855d1889a3e22d5b88461c81ec3ea0e74bb9bf63e60
ToppCellControl-Myeloid-cMonocyte|World / Disease state, Lineage and Cell class

TENT4B ADAMTS2 SIPA1L1 FAM157C CTSS

3.51e-05194855f852f5258617a66a4fbd56d64c7b47272e7b8b60
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M PLA2R1 LOXHD1 ADAMTS2 RBMS3

3.51e-05194855240d122dcb9dd1ab2867503ad85869853adcacae
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M PLA2R1 LOXHD1 ADAMTS2 RBMS3

3.51e-05194855ae7df037592f1c20c9d32be15fe6fc3c562ebeb1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M ANGPT2 ADCY5 RYR2 PLCE1

3.51e-051948555c3b2b05d1e4f146551fe4c920263d8e6ca34de3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M ANGPT2 ADCY5 RYR2 PLCE1

3.51e-05194855ab9cad697f9209d2889bc02b43b502dfeb2ebfef
ToppCell356C-Epithelial_cells|356C / Donor, Lineage, Cell class and subclass (all cells)

CACNA2D2 LGI3 GPRC5C ATP11A SLC6A14

3.60e-05195855d913d0a6c4797d9a873ddea6f340c3f152da1cf3
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M ANGPT2 ESAM GPRC5C RASGRP2

3.60e-05195855815ac5dacd382b11abb32011ed1c0635b0ddc779
ToppCell(7)_Epithelial-A_(AT2)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

CACNA2D2 LGI3 GPRC5C ATP11A SLC6A14

3.60e-05195855c9a6c65ee18d83bf34a4713d306a6e30db1325c2
ToppCellnormal_Lung-Epithelial_cells-AT2|Epithelial_cells / Location, Cell class and cell subclass

CACNA2D2 LGI3 ESAM ATP11A SLC6A14

3.60e-0519585581e13fe337f1d0a83d0deb86a0df797d306cd24d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M LOXHD1 ADAMTS2 RBMS3 HEPH

3.60e-05195855cad6563cc51d212554152c727fc2c249c6a07e4d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M LOXHD1 ADAMTS2 RBMS3 HEPH

3.60e-05195855783bfa8110161cbd6def50ce849cae676c39c458
ToppCellASK440-Epithelial-Type_2|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

CACNA2D2 LGI3 GPRC5C ATP11A SLC6A14

3.69e-05196855754b4202b617165c6994a0b5a9b1e486dccdd44d
ToppCell(5)_Fibroblasts-(5)_Fibroblast-K_(Pericytes)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

ANGPT2 ESAM GPRC5C ADCY5 RASGRP2

3.69e-05196855541b1fcf509e362f6f48720046cb5378aaf7c591
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M ANGPT2 ESAM RASGRP2 PLCE1

3.69e-05196855c16fbd23d9e117831b55ab3da5b08b22dd972432
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M LOXHD1 ADAMTS2 RBMS3 COL27A1

3.69e-05196855ba869f7a86f37fd6d84d6ad69baca0e0faaf5887
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M LOXHD1 ADAMTS2 RBMS3 COL27A1

3.69e-0519685530ad56d49000e4ddce73b4443b3994564bd1e2d6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M ADAMTS2 RBMS3 PREX2 HEPH

3.69e-051968553a6c942e2907aa07b5e12dbf9019d18f7bfca507
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M ADAMTS2 RBMS3 PREX2 HEPH

3.69e-05196855bba88e91cd3e3a6f5a9b443e3a4da33c5b455e70
ToppCellCOVID-19-lung-Pericytes/_Smooth_Muscle|COVID-19 / Disease (COVID-19 only), tissue and cell type

A2M ADCY5 PREX2 RYR2 PLCE1

3.69e-05196855754a3613340932563cd8424d775e18b93c3a1aaa
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PLA2R1 ANGPT2 RBMS3 ESAM PLCE1

3.69e-0519685512d9028f90c057c6e5cff00301793fa550e86c5a
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MMP25 ANGPT2 ESAM NOX4 PREX2

3.69e-05196855ed818de15f84f7f28bd06fd69d7876710da232a0
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MMP25 ANGPT2 ESAM NOX4 PREX2

3.78e-0519785562c0a90869431e582bb7bb329e0b0cc59123d3d1
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

A2M PLA2R1 RBMS3 COL27A1 RYR2

3.78e-05197855f1c8936986123a3151140c374fcd62d6705c530b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

A2M ADAMTS2 RBMS3 COL27A1 PREX2

3.78e-0519785585a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

A2M ADAMTS2 RBMS3 COL27A1 PREX2

3.78e-05197855e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCell356C-Fibroblasts-Fibroblast-K_(Pericytes)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

A2M ANGPT2 ESAM ADCY5 RASGRP2

3.78e-0519785571367bebc23d0e81f60f780d6b0ab3a1783ac014
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

A2M ADAMTS2 RBMS3 COL27A1 PREX2

3.78e-051978559b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MMP25 ANGPT2 ESAM NOX4 PREX2

3.78e-0519785516f0eb047df9d702518f82ee99c6e7dc1350b2fb
ToppCellILEUM-non-inflamed-(8)_Fibroblast-(8)_Pericytes|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ANGPT2 ESAM GPRC5C RASGRP2 PLCE1

3.78e-05197855608328608cef82adc867a449216839622253d486
ToppCell356C-Fibroblasts-Fibroblast-K_(Pericytes)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

A2M ANGPT2 ESAM ADCY5 RASGRP2

3.78e-051978550f9836554ace3f9d155ebafdd719aa26466ca44e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M RBMS3 ESAM PREX2 RYR3

3.87e-0519885507701c73137947ed4a27e225975329235bbb8734
ToppCell367C-Epithelial_cells-Epithelial-E_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CACNA2D2 LGI3 ESAM ATP11A SLC6A14

3.87e-0519885585215015bb86ada0e871c413a4ecdc903a3785ca
ToppCellTransplant_Alveoli_and_parenchyma-Mesenchymal-Smooth_muscle|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X

A2M ANGPT2 ESAM GPRC5C ADCY5

3.87e-0519885589986c7756541df364df516329d10775ba0e78a4
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

A2M MMP25 ANGPT2 ESAM NOX4

3.87e-05198855e1fa02184ce93c4f8aa5cf04b70949cd4c425ff0
ToppCellAdult-Mesenchymal|Adult / Lineage, Cell type, age group and donor

A2M ADAMTS2 RBMS3 NOX4 RYR2

3.87e-0519885526e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

ADAMTS2 DYNC2H1 COL27A1 RYR2 RYR3

3.87e-051988550c4d2c68a42f8a9e964e2dd28092fe75f5216834
ToppCellmetastatic_Brain-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

A2M ANGPT2 ESAM GPRC5C PLCE1

3.87e-0519885586a4c8e859ce11a95875f8844963baeb1ba898ec
ToppCellParenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FRRS1L GLRB CA10 ADCY5 RYR2

3.87e-05198855d1827e3707b929e3a3562989a0c11537d344e164
ToppCellCOVID-19-lung-Fibroblast|lung / Disease (COVID-19 only), tissue and cell type

A2M PLA2R1 ADAMTS2 COL27A1 RYR2

3.87e-05198855df3de77216f5c5d6141ec44d01c56b942f611838
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M RBMS3 ESAM PREX2 RYR3

3.87e-05198855fa84bf8533d1b91d2c2bcf06b710670605072b89
ToppCell367C-Epithelial_cells-Epithelial-E_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CACNA2D2 LGI3 ESAM ATP11A SLC6A14

3.87e-0519885538349e42a3f1fb700ff6dfd89c4bf5ff97f1a3e9
ToppCellSkin-Endothelial|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.

A2M RBMS3 ESAM CTSS PREX2

3.96e-051998556b3ef5d8f87cdfe5401d05f19339ddfcd9cda476
ToppCellSkin-Mesangial|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.

A2M LOXHD1 RBMS3 TTLL4 MARCHF4

3.96e-05199855bcb78838a91cc7828680fb413fbacdb091c5fac0
Druglead compounds

CSNK2A2 CA10 ADCY5 RYR2 RYR3 PLCE1

1.84e-05150836CID000073212
Drugheptachlorobiphenyl

MARS1 UROD

3.93e-053832CID000050102
Drug2-hydroxycarbazole

RYR2 RYR3

3.93e-053832CID000093551
Drugcis-diammineplatinum(II

RYR2 RYR3

3.93e-053832CID000159790
Drug2-hydroxyheptanoic acid

RYR2 RYR3

3.93e-053832CID002750949
DrugRyanodyl 3-(pyridine-3-carboxylate

RYR2 RYR3

3.93e-053832CID005748312
Drug8N3-cADPR

RYR2 RYR3

3.93e-053832CID000127713
Drugaminodantrolene

RYR2 RYR3

3.93e-053832CID009570289
Drugbaclofen

CACNA2D2 GLRB GLRA3 ADCY5 RYR2 RYR3

7.12e-05191836CID000002284
Drugiso-THAZ

GLRB GLRA3

7.84e-054832CID003047783
Drugprotostrychnine

GLRB GLRA3

7.84e-054832CID005320746
Drug7-nitroindoline

GLRB GLRA3

7.84e-054832CID013566747
Drug2-(phosphonomethyl)phenylalanine

GLRB GLRA3

7.84e-054832CID000383689
DrugSC-49648

GLRB GLRA3

7.84e-054832CID000195696
DrugPCB74

RYR2 RYR3

7.84e-054832CID000036218
Drugakuammiline

GLRB GLRA3

7.84e-054832CID005367018
Drug148504-47-6

RYR2 RYR3

7.84e-054832CID006444275
DrugNSC381080

GLRB GLRA3

7.84e-054832CID000165497
DrugN-methyl-THIP

GLRB GLRA3

7.84e-054832CID000134373
DrugSC-48981

GLRB GLRA3

7.84e-054832CID000126573
DrugSC 38249

RYR2 RYR3

7.84e-054832CID000134834
DrugSC-50132

GLRB GLRA3

7.84e-054832CID000195719
DrugAC1L1U7A

RYR2 RYR3

7.84e-054832CID000035682
DrugSR 42641

GLRB GLRA3

7.84e-054832CID000129049
Druggluconate

MMP25 ABRA COL27A1 GLRB UROD ADCY5 LGI1

8.61e-05287837CID000000604
Drugaldosterone

MMP25 ABRA CACNA2D2 COL27A1 NOX4 SAR1A RYR2 RYR3

1.00e-04397838CID000005839
Drugazetidine-3-carboxylic acid

GLRB GLRA3

1.30e-045832CID000093192
DrugLindane

GLRB GLRA3

1.30e-045832DB00431
DrugCao C

GLRB GLRA3

1.30e-045832CID000166617
Drugoxanilide

GLRB GLRA3

1.30e-045832CID000069288
Drugiso-THAO

GLRB GLRA3

1.30e-045832CID000127199
DrugALX1393

GLRB GLRA3

1.30e-045832CID016078939
Drugpleiocarpamine

GLRB GLRA3

1.30e-045832CID000558637
Drugmafoprazine

GLRB GLRA3

1.30e-045832CID000071241
Druggevotroline

GLRB GLRA3

1.30e-045832CID000060546
Drughalothane

CACNA2D2 GLRB GLRA3 ADCY5 RYR2 RYR3 PLCE1

1.50e-04314837CID000003562
DrugTHAZ

GLRB GLRA3

1.95e-046832CID000171289
DrugmV GABA

GLRB GLRA3

1.95e-046832CID000128435
Drugcaged glycine

GLRB GLRA3

1.95e-046832CID000192642
Drugbrometone

GLRB GLRA3

1.95e-046832CID000006424
DrugMBED

RYR2 RYR3

1.95e-046832CID000129958
Drugminaxolone

GLRB GLRA3

1.95e-046832CID000071960
Drugtalcum powder

ABRA MARS1

1.95e-046832CID000517272
Drugchloro-m-cresol

RYR2 RYR3

1.95e-046832CID000012008
Drugthiomuscimol

GLRB GLRA3

1.95e-046832CID000005448
DrugAC1O528X

RYR2 RYR3

1.95e-046832CID006475857
DrugNSC114784

RYR2 RYR3

1.95e-046832CID000419425
Drugthio-THIP

GLRB GLRA3

1.95e-046832CID000656720
DrugAC1L90PQ

GLRB GLRA3

1.95e-046832CID000436036
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR2 RYR3

2.40e-053842DOID:3529 (implicated_via_orthology)
DiseaseBenign Hereditary Chorea

CACNA2D2 ADCY5

2.40e-053842C0393584
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR2 RYR3

2.40e-053842DOID:8545 (implicated_via_orthology)
Diseaseuremia (implicated_via_orthology)

ANGPT2 AGL

4.79e-054842DOID:4676 (implicated_via_orthology)
Diseasecentronuclear myopathy (implicated_via_orthology)

MTMR6 MTM1

1.67e-047842DOID:14717 (implicated_via_orthology)
Diseasedental caries

ABRA ANGPT2 ADAMTS2 RBMS3 ZGRF1

1.99e-04187845EFO_0003819
Diseasecentronuclear myopathy X-linked (implicated_via_orthology)

MTMR6 MTM1

2.85e-049842DOID:0111225 (implicated_via_orthology)
Diseasesquamous cell carcinoma

NOX4 ATP11A CTSS

9.35e-0467843EFO_0000707
Diseasewellbeing measurement, alcohol consumption measurement

MMP25 RBMS3 PREX2

1.25e-0374843EFO_0007869, EFO_0007878
Diseasepulmonary hypertension (biomarker_via_orthology)

ANGPT2 RYR2 RYR3

1.56e-0380843DOID:6432 (biomarker_via_orthology)
Diseaseplatelet reactivity measurement, response to clopidogrel

PLEKHA5 PLCE1

1.95e-0323842EFO_0004985, GO_1903493
Diseasebasal cell carcinoma

FAM157C NOX4 ATP11A CTSS

2.11e-03189844EFO_0004193
DiseaseCharcot-Marie-Tooth disease (implicated_via_orthology)

MTMR6 MTM1

2.12e-0324842DOID:10595 (implicated_via_orthology)
DiseaseHVA measurement

GARNL3 RBMS3

2.49e-0326842EFO_0005131
DiseaseLewy body dementia, Lewy body dementia measurement

ABRA GARNL3

2.49e-0326842EFO_0006792, EFO_0006799
Diseasemigraine disorder, pulse pressure measurement

DYNC2H1 PLCE1

2.49e-0326842EFO_0005763, MONDO_0005277

Protein segments in the cluster

PeptideGeneStartEntry
QSPVNFYRWKIEQLQ

CATSPERG

131

Q6ZRH7
RVQDVFEKYNWPNRT

CACNA2D2

406

Q9NY47
NAYRAGLQPVSKWQA

ALKBH1

76

Q13686
PQRQNTNKFNGIKWY

ANGPT2

461

O15123
ARKPQYDIWGNTVNV

ADCY5

1191

O95622
NVCRWAYLQQKPDTG

ADAMTS2

341

O95450
YIQDPKGNRIAQWQS

A2M

166

P01023
KRAYSRKPWDNQQQT

MROH7

1166

Q68CQ1
QNQSKYTQNGRPWPR

RBMS3

231

Q6XE24
QAWYLLQPRDNGNKS

RASA2

286

Q15283
YRVNIFLRQKWNDPR

GLRA3

91

O75311
NYWKLETPAQFRQRS

KAT2A

266

Q92830
TPWKRRNYNQGVVGL

TENT4B

106

Q8NDF8
QAKRWLYQRPQASHQ

UROD

176

P06132
SWPQNGKTYLVRGRQ

MMP25

421

Q9NPA2
TYKWKRQVTQRNPVG

RASGRP2

126

Q7LDG7
SYNPKQNDSERLQGW

MTMR6

111

Q9Y217
KVPWFDQQNGRTYLK

H1-10

76

Q92522
RIPYWRTDNNKNLAQ

LIPJ

31

Q5W064
RQGKQYTFPANRWLD

LOXHD1

776

Q8IVV2
FRGWYIRTEKLQQNQ

NCCRP1

136

Q6ZVX7
NRQQQRKSQLFWGLP

C9orf131

186

Q5VYM1
GNQVLWRSYVQIQNK

NRDE2

996

Q9H7Z3
KNNVRSAWYRGQSPA

NOL6

271

Q9H6R4
PVNQNWERYLAEAQG

POLG

436

P54098
KPSEDIYKNWRRQQQ

FAM157C

61

P0CG43
YRVNIFLRQKWNDPR

GLRB

101

P48167
QIKQWYETNAPRAGR

KRT20

101

P35900
RPWNTQNTRNRINGK

MANEA

366

Q5SRI9
NKFWQENRPDYVNIQ

NOX4

481

Q9NPH5
WELPKYNASSQQQRE

ARHGAP12

386

Q8IWW6
YVNQGEILRTEQWPR

PTOV1

286

Q86YD1
RQKYWNKLQTLRQQP

PANK4

481

Q9NVE7
KDGKNSQVFRNPYVW

GPRC5C

426

Q9NQ84
IKSWLRNQPAEYRNN

DYNC2H1

2126

Q8NCM8
NYIEDLQNGPIRKNW

DUSP11

241

O75319
YNVGQWAKEIQRNPA

FRRS1L

176

Q9P0K9
GLTQLQVKTWYQNRR

BARX2

171

Q9UMQ3
FNLGRYWTKQGPQQT

GLB1L

571

Q6UWU2
STPLQQWRQGEYKCV

IGHD

71

P01880
TWNPFKLQYQLRNVR

GOLPH3L

146

Q9H4A5
PAKQAVRFRAWNGQI

COL27A1

1781

Q8IZC6
VPSWGNQDDYQLVRK

CSNK2A2

31

P19784
SPRSKPAVQYQWDRQ

ESAM

176

Q96AP7
PSVYRIFKRWQAVNQ

MARCHF4

296

Q9P2E8
NIIRGWDRYLTNQKN

MEAF6

56

Q9HAF1
NPAVTQYRWAKRGQI

KIRREL3

276

Q8IZU9
RVPSQWQRNITYKSN

CTSS

96

P25774
WQRNITYKSNPNRIL

CTSS

101

P25774
PNNRAQKLQYRVNEW

CA10

311

Q9NS85
WTYGIQQDVKNRRNP

RYR2

1016

Q92736
NNQRVPQYRAILWRK

GARNL3

131

Q5VVW2
GNNWARAIKYRQENQ

NIPSNAP1

201

Q9BPW8
VRANKVNWQSYLQGQ

ATP6V1H

26

Q9UI12
DNLWYRAVIKEQQPN

TDRD6

1366

O60522
PDQRQQWLRKQYVSL

PLCE1

1016

Q9P212
SNFWRQQKPIYARER

ODAD4

236

Q96NG3
QWNYAPKGRNVITNQ

HEPH

36

Q9BQS7
PFRNNNKWQRNASKG

SIPA1L1

1061

O43166
TPTQVGNWFKNRRQR

SIX3

246

O95343
QARRVWKNYLPAING

SAR1A

81

Q9NR31
GYRNKNVRQKTWRPN

CCDC59

26

Q9P031
ERQFWIGFNKRNPLN

PLA2R1

731

Q13018
WDNPARFAKQIRQQY

SPAG17

636

Q6Q759
QQKYSPVGNLKGRWQ

ABRA

236

Q8N0Z2
KNRSWPRINSATGQY

CLNK

26

Q7Z7G1
EPWYNQKTESERQRN

ATP11A

326

P98196
RWKDQNIEYEHQNPR

ZNF440

46

Q8IYI8
NYYIRWNPRIKQQQP

MTM1

536

Q13496
FRGNRQTNVLSKPEW

RINT1

321

Q6NUQ1
QGWTYGIQQDLKNKR

RYR3

1001

Q15413
PQYKNWRGQTIREKR

NDUFAF2

36

Q8N183
RRPTKQDSIQWVYNS

PREX2

746

Q70Z35
LESNPYRSRKQRQEW

WDR46

486

O15213
QESKRYWQNLEANVP

ZC3H7A

676

Q8IWR0
LRCNQDYTGWNKPRV

USP37

316

Q86T82
VETAREGKQYWNPRN

ZGRF1

801

Q86YA3
IRGFVQKQQYLRWPE

TLR5

806

O60602
WQQRQFYNKQSTLPR

PLEKHA5

506

Q9HAU0
QARRVWKNYLPAING

SAR1B

81

Q9Y6B6
QLPSEQYWNKVALQR

SLC6A14

211

Q9UN76
QPRYFNILTTQWEQK

TTLL4

1041

Q14679
NQYIQVNEPWKRIKG

MARS1

716

P56192
IQDQNAQTRWKQGRY

ZNF789

161

Q5FWF6
SRPNRKYTWNDVGQL

AGL

186

P35573
QRPVIYQWNKATQLF

LGI1

406

O95970
SQAPVIYQWSRTQKQ

LGI3

396

Q8N145