Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cytoskeletal motor activity	MYH1 MYH6 MYH7 MYO18A KIF20B MYO16	1.37e-05	118	88	6	GO:0003774
GeneOntologyMolecularFunction	ATP-dependent activity	MYH1 MYH6 MYH7 MDN1 ANXA5 CFTR HELZ2 MYO18A KIF20B ABCC10 NLRP3 ABCB4	1.56e-05	614	88	12	GO:0140657
GeneOntologyMolecularFunction	cytoskeletal protein binding	SPTBN4 CCDC88C MYH1 MYH6 MYH7 GIT1 NUMA1 MYO18A ROCK1 FSD1 RP1 JAKMIP1 UTRN KIF20B MYO16	8.45e-05	1099	88	15	GO:0008092
GeneOntologyMolecularFunction	protein domain specific binding	CCDC88C SCAF1 ARHGAP6 CARD9 CFTR SH3KBP1 NUMA1 RAPGEF2 SSTR2 ARHGEF16 KIF20B STX1B CARD14	1.15e-04	875	88	13	GO:0019904
GeneOntologyMolecularFunction	ATP hydrolysis activity	MYH7 MDN1 CFTR HELZ2 MYO18A KIF20B ABCC10 NLRP3 ABCB4	1.41e-04	441	88	9	GO:0016887
GeneOntologyMolecularFunction	PDZ domain binding	CCDC88C CFTR RAPGEF2 SSTR2 ARHGEF16	2.13e-04	123	88	5	GO:0030165
GeneOntologyMolecularFunction	enzyme regulator activity	CCDC88C ARHGAP6 PSME4 GIT1 ANXA5 ADGRB3 PPP1R37 BIRC2 ROCK1 RAPGEF2 ARHGEF16 CEP43 ARHGAP21 SLX4 KNG1 NLRP3	4.24e-04	1418	88	16	GO:0030234
GeneOntologyMolecularFunction	actin filament binding	SPTBN4 MYH1 MYH6 MYH7 MYO18A MYO16	5.04e-04	227	88	6	GO:0051015
GeneOntologyMolecularFunction	microfilament motor activity	MYH1 MYH6 MYH7	6.24e-04	38	88	3	GO:0000146
GeneOntologyMolecularFunction	ATPase-coupled inorganic anion transmembrane transporter activity	CFTR ABCC10	8.44e-04	10	88	2	GO:0043225
GeneOntologyMolecularFunction	ABC-type transporter activity	CFTR ABCC10 ABCB4	1.32e-03	49	88	3	GO:0140359
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ANXA5 CFTR ABCC10 ABCB4	1.38e-03	109	88	4	GO:0042626
GeneOntologyMolecularFunction	peptide hormone binding	ANXA5 RXFP2 SCTR	1.84e-03	55	88	3	GO:0017046
GeneOntologyBiologicalProcess	spermatid development	ADGB FANCG PSME4 SPEF2 CCDC62 CFTR SYCP1 CEP131 CCDC136	1.47e-06	262	86	9	GO:0007286
GeneOntologyBiologicalProcess	spermatid differentiation	ADGB FANCG PSME4 SPEF2 CCDC62 CFTR SYCP1 CEP131 CCDC136	2.00e-06	272	86	9	GO:0048515
GeneOntologyBiologicalProcess	germ cell development	ADGB FANCG PSME4 SPEF2 CCDC62 TUT7 CFTR RXFP2 SYCP1 CEP131 CCDC136	5.11e-06	482	86	11	GO:0007281
GeneOntologyBiologicalProcess	cellular process involved in reproduction in multicellular organism	ADGB FANCG PSME4 SPEF2 CCDC62 TUT7 CFTR RXFP2 SYCP1 CEP131 CCDC136	1.18e-05	527	86	11	GO:0022412
GeneOntologyBiologicalProcess	mucociliary clearance	CCDC88C VANGL1 SPEF2	1.94e-05	13	86	3	GO:0120197
GeneOntologyBiologicalProcess	regulation of microtubule-based process	CCDC88C GIT1 ANXA5 NUMA1 ROCK1 CEP131 FSD1 RP1	3.06e-05	293	86	8	GO:0032886
GeneOntologyBiologicalProcess	supramolecular fiber organization	SPTBN4 CCDC88C ARHGAP6 MYH6 MYH7 GIT1 KRT31 KRT32 KRT33A SH3KBP1 NUMA1 ROCK1 FSD1 RP1	3.91e-05	957	86	14	GO:0097435
GeneOntologyBiologicalProcess	regulation of microtubule cytoskeleton organization	CCDC88C GIT1 NUMA1 ROCK1 FSD1 RP1	9.47e-05	176	86	6	GO:0070507
GeneOntologyBiologicalProcess	microtubule-based process	CCDC88C GIT1 VANGL1 GCC2 SPEF2 ANXA5 NUMA1 ROCK1 CEP131 FSD1 RP1 CEP43 ARHGAP21 KIF20B	1.15e-04	1058	86	14	GO:0007017
GeneOntologyBiologicalProcess	apical constriction	CCDC88C ROCK1	1.70e-04	5	86	2	GO:0003383
GeneOntologyBiologicalProcess	late endosome to Golgi transport	GCC2 AP5Z1	2.55e-04	6	86	2	GO:0034499
GeneOntologyBiologicalProcess	regulation of hydrolase activity	ARHGAP6 SENP1 CARD9 MBP BIRC2 ROCK1 RAPGEF2 CMYA5 ARHGEF16 PLXNA2 KNG1 NLRP3	2.77e-04	878	86	12	GO:0051336
GeneOntologyCellularComponent	myosin filament	MYH1 MYH6 MYH7 MYO18A	3.63e-06	25	89	4	GO:0032982
GeneOntologyCellularComponent	myosin complex	MYH1 MYH6 MYH7 MYO18A MYO16	5.22e-06	59	89	5	GO:0016459
GeneOntologyCellularComponent	myosin II complex	MYH1 MYH6 MYH7 MYO18A	5.81e-06	28	89	4	GO:0016460
GeneOntologyCellularComponent	supramolecular fiber	SPTBN4 ARHGAP6 MYH1 MYH6 MYH7 KRT31 KRT32 KRT33A ANXA5 NUMA1 MYO18A SCTR FSD1 RP1 JAKMIP1 CMYA5 KIF20B	8.43e-06	1179	89	17	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	SPTBN4 ARHGAP6 MYH1 MYH6 MYH7 KRT31 KRT32 KRT33A ANXA5 NUMA1 MYO18A SCTR FSD1 RP1 JAKMIP1 CMYA5 KIF20B	9.21e-06	1187	89	17	GO:0099081
GeneOntologyCellularComponent	muscle myosin complex	MYH1 MYH6 MYH7	4.01e-05	16	89	3	GO:0005859
GeneOntologyCellularComponent	mitotic spindle pole	GIT1 NUMA1 KIF20B	8.14e-04	43	89	3	GO:0097431
Domain	IQ	ADGB MYH1 MYH6 MYH7 MYO18A CEP131 MYO16	9.79e-08	81	87	7	SM00015
Domain	IQ_motif_EF-hand-BS	ADGB MYH1 MYH6 MYH7 MYO18A CEP131 MYO16	2.03e-07	90	87	7	IPR000048
Domain	IQ	ADGB MYH1 MYH6 MYH7 MYO18A CEP131 MYO16	2.55e-07	93	87	7	PS50096
Domain	Myosin_head_motor_dom	MYH1 MYH6 MYH7 MYO18A MYO16	8.68e-07	38	87	5	IPR001609
Domain	MYOSIN_MOTOR	MYH1 MYH6 MYH7 MYO18A MYO16	8.68e-07	38	87	5	PS51456
Domain	Myosin_head	MYH1 MYH6 MYH7 MYO18A MYO16	8.68e-07	38	87	5	PF00063
Domain	MYSc	MYH1 MYH6 MYH7 MYO18A MYO16	8.68e-07	38	87	5	SM00242
Domain	Myosin_tail_1	MYH1 MYH6 MYH7 MYO18A	1.28e-06	18	87	4	PF01576
Domain	Myosin_tail	MYH1 MYH6 MYH7 MYO18A	1.28e-06	18	87	4	IPR002928
Domain	Myosin-like_IQ_dom	MYH1 MYH6 MYH7 MYO18A	1.61e-06	19	87	4	IPR027401
Domain	-	MYH1 MYH6 MYH7 MYO18A	1.61e-06	19	87	4	4.10.270.10
Domain	P-loop_NTPase	MYH1 MYH6 MYH7 NLRP9 MDN1 SPEF2 CFTR HELZ2 MYO18A KIF20B MYO16 ABCC10 CARD14 NLRP3 ABCB4	7.86e-06	848	87	15	IPR027417
Domain	TMEM191C	TMEM191B TMEM191C	2.14e-05	2	87	2	PF15194
Domain	TMEM191B/C	TMEM191B TMEM191C	2.14e-05	2	87	2	IPR028186
Domain	Myosin_N	MYH1 MYH6 MYH7	4.27e-05	15	87	3	PF02736
Domain	Myosin_N	MYH1 MYH6 MYH7	4.27e-05	15	87	3	IPR004009
Domain	-	NLRP9 CARD9 BIRC2 CARD14 NLRP3	7.35e-05	93	87	5	1.10.533.10
Domain	DEATH-like_dom	NLRP9 CARD9 BIRC2 CARD14 NLRP3	9.90e-05	99	87	5	IPR011029
Domain	ABC_membrane	CFTR ABCC10 ABCB4	1.84e-04	24	87	3	PF00664
Domain	ABC_TM1F	CFTR ABCC10 ABCB4	2.94e-04	28	87	3	PS50929
Domain	CARD	CARD9 BIRC2 CARD14	2.94e-04	28	87	3	PF00619
Domain	ABC1_TM_dom	CFTR ABCC10 ABCB4	2.94e-04	28	87	3	IPR011527
Domain	IQ	MYH1 MYH6 MYO18A CEP131	3.36e-04	71	87	4	PF00612
Domain	CARD	CARD9 BIRC2 CARD14	3.99e-04	31	87	3	IPR001315
Domain	CARD	CARD9 BIRC2 CARD14	4.81e-04	33	87	3	PS50209
Domain	AAA+_ATPase	MDN1 CFTR HELZ2 ABCC10 ABCB4	5.65e-04	144	87	5	IPR003593
Domain	AAA	MDN1 CFTR HELZ2 ABCC10 ABCB4	5.65e-04	144	87	5	SM00382
Domain	PDZ	MYO18A RAPGEF2 ARHGAP21 CARD14 PDZRN4	6.40e-04	148	87	5	SM00228
Domain	-	MYO18A RAPGEF2 ARHGAP21 CARD14 PDZRN4	6.80e-04	150	87	5	2.30.42.10
Domain	PDZ	MYO18A RAPGEF2 ARHGAP21 CARD14 PDZRN4	7.01e-04	151	87	5	PS50106
Domain	PDZ	MYO18A RAPGEF2 ARHGAP21 CARD14 PDZRN4	7.22e-04	152	87	5	IPR001478
Domain	ABC_transporter_CS	CFTR ABCC10 ABCB4	9.83e-04	42	87	3	IPR017871
Domain	Keratin_I	KRT31 KRT32 KRT33A	1.13e-03	44	87	3	IPR002957
Domain	ABC_tran	CFTR ABCC10 ABCB4	1.45e-03	48	87	3	PF00005
Domain	ABC_TRANSPORTER_2	CFTR ABCC10 ABCB4	1.45e-03	48	87	3	PS50893
Domain	ABC_TRANSPORTER_1	CFTR ABCC10 ABCB4	1.54e-03	49	87	3	PS00211
Domain	ABC_transporter-like	CFTR ABCC10 ABCB4	1.63e-03	50	87	3	IPR003439
Domain	LRR_6	NLRP9 PPP1R37 NLRP3	2.15e-03	55	87	3	PF13516
Domain	Intermediate_filament_CS	KRT31 KRT32 KRT33A	3.17e-03	63	87	3	IPR018039
Domain	PDZ	MYO18A RAPGEF2 ARHGAP21 PDZRN4	4.27e-03	141	87	4	PF00595
Domain	Filament	KRT31 KRT32 KRT33A	4.44e-03	71	87	3	SM01391
Domain	Prefoldin	CCDC62 KIF20B WTAP	4.62e-03	72	87	3	IPR009053
Domain	IF	KRT31 KRT32 KRT33A	4.62e-03	72	87	3	PS00226
Domain	DAPIN	NLRP9 NLRP3	4.66e-03	22	87	2	PS50824
Domain	PYRIN	NLRP9 NLRP3	4.66e-03	22	87	2	PF02758
Pathway	REACTOME_DEVELOPMENTAL_BIOLOGY	SPTBN4 AIMP2 GIT1 KRT31 KRT32 KRT33A SH3KBP1 ROCK1 STX1B PLXNA2	9.23e-05	502	65	10	MM14537
Pathway	REACTOME_RHOQ_GTPASE_CYCLE	GIT1 VANGL1 CFTR ARHGAP21	1.45e-04	58	65	4	MM15602
Pathway	REACTOME_RHOQ_GTPASE_CYCLE	GIT1 VANGL1 CFTR ARHGAP21	1.55e-04	59	65	4	M41812
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SPTBN4 CCDC88C EPS15L1 SENP1 MDN1 GIT1 SH3KBP1 NUMA1 ADGRB3 ROCK1 CEP131 JAKMIP1 QSER1 RAPGEF2 ARHGAP21	2.99e-08	963	91	15	28671696
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	SPTBN4 MYH1 MYH6 MYH7 MDN1 KRT31 PPRC1 KRT33A PPFIA2 SPEF2 NUMA1 SYCP1 RETREG1 MYO18A JAKMIP1 ARHGAP21 PLXNA2 ABCB4	3.14e-08	1442	91	18	35575683
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	SPTBN4 PRUNE2 ARHGAP6 EPS15L1 SENP1 AIMP2 KCNQ5 GCC2 PPFIA2 MBP ANKIB1 QSER1 LRBA RAPGEF2 ARHGEF16 UTRN CEP43	2.84e-07	1489	91	17	28611215
Pubmed	Whn and mHa3 are components of the genetic hierarchy controlling hair follicle differentiation.	KRT31 KRT32 KRT33A	3.45e-07	6	91	3	10559501
Pubmed	Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks.	CCDC88C EPS15L1 PLVAP PPFIA2 SH3KBP1 ROCK1	4.93e-07	111	91	6	22558309
Pubmed	Diversity in transcriptional start site selection and alternative splicing affects the 5'-UTR of mouse striated muscle myosin transcripts.	MYH1 MYH6 MYH7	6.02e-07	7	91	3	16819597
Pubmed	Genes for skeletal muscle myosin heavy chains are clustered and are not located on the same mouse chromosome as a cardiac myosin heavy chain gene.	MYH1 MYH6 MYH7	9.61e-07	8	91	3	3864153
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	SPTBN4 EPS15L1 GIT1 PPRC1 RETREG1 ADGRB3 BIRC2 JAKMIP1 LRBA RAPGEF2 CMYA5 EIF2AK1 UTRN ARHGAP21 SLX4	1.19e-06	1285	91	15	35914814
Pubmed	Human hair keratins.	KRT31 KRT32 KRT33A	1.44e-06	9	91	3	7686952
Pubmed	The catalog of human hair keratins. I. Expression of the nine type I members in the hair follicle.	KRT31 KRT32 KRT33A	2.05e-06	10	91	3	10391933
Pubmed	Loss of Prox1 in striated muscle causes slow to fast skeletal muscle fiber conversion and dilated cardiomyopathy.	MYH1 MYH6 MYH7	6.18e-06	14	91	3	24938781
Pubmed	Reversible epigenetic modifications of the two cardiac myosin heavy chain genes during changes in expression.	MYH6 MYH7	6.77e-06	2	91	2	21526716
Pubmed	Characterization of human cardiac myosin heavy chain genes.	MYH6 MYH7	6.77e-06	2	91	2	2726733
Pubmed	Human cardiac myosin heavy chain genes and their linkage in the genome.	MYH6 MYH7	6.77e-06	2	91	2	3037493
Pubmed	β-myosin heavy chain is induced by pressure overload in a minor subpopulation of smaller mouse cardiac myocytes.	MYH6 MYH7	6.77e-06	2	91	2	21778428
Pubmed	Structural organization of the human cardiac alpha-myosin heavy chain gene (MYH6).	MYH6 MYH7	6.77e-06	2	91	2	8307559
Pubmed	Molecular cloning and characterization of human cardiac alpha- and beta-form myosin heavy chain complementary DNA clones. Regulation of expression during development and pressure overload in human atrium.	MYH6 MYH7	6.77e-06	2	91	2	2969919
Pubmed	Distribution and structure-function relationship of myosin heavy chain isoforms in the adult mouse heart.	MYH6 MYH7	6.77e-06	2	91	2	17575272
Pubmed	Neonatal cardiomyopathy in mice homozygous for the Arg403Gln mutation in the alpha cardiac myosin heavy chain gene.	MYH6 MYH7	6.77e-06	2	91	2	9884344
Pubmed	E-cigarette exposure with or without heating the e-liquid induces differential remodeling in the lungs and right heart of mice.	CARD9 NLRP3	6.77e-06	2	91	2	35489388
Pubmed	Role of microtubules versus myosin heavy chain isoforms in contractile dysfunction of hypertrophied murine cardiocytes.	MYH6 MYH7	6.77e-06	2	91	2	12750067
Pubmed	Characterization of diverse forms of myosin heavy chain expressed in adult human skeletal muscle.	MYH1 MYH7	6.77e-06	2	91	2	2421254
Pubmed	Transgenic mouse α- and β-cardiac myosins containing the R403Q mutation show isoform-dependent transient kinetic differences.	MYH6 MYH7	6.77e-06	2	91	2	23580644
Pubmed	β-Myosin heavy chain variant Val606Met causes very mild hypertrophic cardiomyopathy in mice, but exacerbates HCM phenotypes in mice carrying other HCM mutations.	MYH6 MYH7	6.77e-06	2	91	2	24829265
Pubmed	Cardiac myosin heavy chain mRNA expression and myocardial function in the mouse heart.	MYH6 MYH7	6.77e-06	2	91	2	2036722
Pubmed	Ensemble force changes that result from human cardiac myosin mutations and a small-molecule effector.	MYH6 MYH7	6.77e-06	2	91	2	25937279
Pubmed	Myocardial contraction is 5-fold more economical in ventricular than in atrial human tissue.	MYH6 MYH7	6.77e-06	2	91	2	15621050
Pubmed	Annexin V is directly involved in cystic fibrosis transmembrane conductance regulator's chloride channel function.	ANXA5 CFTR	6.77e-06	2	91	2	17869070
Pubmed	Functional effects of the hypertrophic cardiomyopathy R403Q mutation are different in an alpha- or beta-myosin heavy chain backbone.	MYH6 MYH7	6.77e-06	2	91	2	18480046
Pubmed	Murine pulmonary myocardium: developmental analysis of cardiac gene expression.	MYH6 MYH7	6.77e-06	2	91	2	7919499
Pubmed	Long-Read Sequence Confirmed a Large Deletion Including MYH6 and MYH7 in an Infant of Atrial Septal Defect and Atrial Arrhythmias.	MYH6 MYH7	6.77e-06	2	91	2	34384224
Pubmed	Annexin A5 increases the cell surface expression and the chloride channel function of the DeltaF508-cystic fibrosis transmembrane regulator.	ANXA5 CFTR	6.77e-06	2	91	2	18773956
Pubmed	Effect of CFTR correctors on the traffic and the function of intracellularly retained ABCB4 variants.	CFTR ABCB4	6.77e-06	2	91	2	33650203
Pubmed	Human cardiac myosin heavy chain gene mapped within chromosome region 14q11.2----q13.	MYH6 MYH7	6.77e-06	2	91	2	2494889
Pubmed	All-atom molecular dynamics simulations of actin-myosin interactions: a comparative study of cardiac α myosin, β myosin, and fast skeletal muscle myosin.	MYH6 MYH7	6.77e-06	2	91	2	24224850
Pubmed	Myosin heavy chain composition and the economy of contraction in healthy and diseased human myocardium.	MYH6 MYH7	6.77e-06	2	91	2	16088376
Pubmed	Complete sequence of human cardiac alpha-myosin heavy chain gene and amino acid comparison to other myosins based on structural and functional differences.	MYH6 MYH7	6.77e-06	2	91	2	1776652
Pubmed	Endogenous slow and fast myosin dynamics in myofibers isolated from mice expressing GFP-Myh7 and Kusabira Orange-Myh1.	MYH1 MYH7	6.77e-06	2	91	2	35759444
Pubmed	Diastolic dysfunction and altered energetics in the alphaMHC403/+ mouse model of familial hypertrophic cardiomyopathy.	MYH6 MYH7	6.77e-06	2	91	2	9541509
Pubmed	Effect of Annexin A5 on CFTR: regulated traffic or scaffolding?	ANXA5 CFTR	6.77e-06	2	91	2	21067452
Pubmed	A family of microRNAs encoded by myosin genes governs myosin expression and muscle performance.	MYH1 MYH6 MYH7	9.47e-06	16	91	3	19922871
Pubmed	Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.	CDK17 NUMA1 RAPGEF2 ARHGEF16 ARHGAP21 WTAP	1.11e-05	190	91	6	15161933
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CCDC88C CDK17 MDN1 KCNQ5 GIT1 CEP131 FSD1 RAPGEF2 ARHGEF16 UTRN ARHGAP21	1.57e-05	861	91	11	36931259
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	NBAS EPS15L1 VANGL1 GCC2 NUMA1 RETREG1 JPT1 LRBA ARHGEF16	1.85e-05	568	91	9	37774976
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	VANGL1 CFTR MBP PPP1R37 ROCK1 LRBA ARHGEF16 ARHGAP21 PLXNA2	1.88e-05	569	91	9	30639242
Pubmed	Endogenous retinoic acid signaling colocalizes with advanced expression of the adult smooth muscle myosin heavy chain isoform during development of the ductus arteriosus.	MYH6 MYH7	2.03e-05	3	91	2	8620598
Pubmed	Heterogeneous myocyte enhancer factor-2 (Mef2) activation in myocytes predicts focal scarring in hypertrophic cardiomyopathy.	MYH6 MYH7	2.03e-05	3	91	2	20923879
Pubmed	Mouse embryonic stem cells express the cardiac myosin heavy chain genes during development in vitro.	MYH6 MYH7	2.03e-05	3	91	2	1694848
Pubmed	Differences between nuclear run-off and mRNA levels for multidrug resistance gene expression in the cephalocaudal axis of the mouse intestine.	CFTR ABCB4	2.03e-05	3	91	2	8547326
Pubmed	Discordant on/off switching of gene expression in myocytes during cardiac hypertrophy in vivo.	MYH6 MYH7	2.03e-05	3	91	2	18755891
Pubmed	Knockout of secretin receptor reduces biliary damage and liver fibrosis in Mdr2-/- mice by diminishing senescence of cholangiocytes.	SCTR ABCB4	2.03e-05	3	91	2	29977037
Pubmed	The expression of myosin heavy chain (MHC) genes in human skeletal muscle is related to metabolic characteristics involved in the pathogenesis of type 2 diabetes.	MYH1 MYH7	2.03e-05	3	91	2	21470888
Pubmed	Conotruncal anomalies in the trisomy 16 mouse: an immunohistochemical analysis with emphasis on the involvement of the neural crest.	MYH6 MYH7	2.03e-05	3	91	2	11066038
Pubmed	Severe heart failure and early mortality in a double-mutation mouse model of familial hypertrophic cardiomyopathy.	MYH6 MYH7	2.03e-05	3	91	2	18362229
Pubmed	N4BP1 is a newly identified nucleolar protein that undergoes SUMO-regulated polyubiquitylation and proteasomal turnover at promyelocytic leukemia nuclear bodies.	SENP1 N4BP1	2.03e-05	3	91	2	20233849
Pubmed	Myosin heavy chain gene expression in mouse embryoid bodies. An in vitro developmental study.	MYH6 MYH7	2.03e-05	3	91	2	1939265
Pubmed	Structural and developmental analysis of two linked myosin heavy chain genes.	MYH1 MYH7	2.03e-05	3	91	2	1371481
Pubmed	ADGB variants cause asthenozoospermia and male infertility.	ADGB SPEF2	2.03e-05	3	91	2	36995441
Pubmed	Mutation in myosin heavy chain 6 causes atrial septal defect.	MYH6 MYH7	2.03e-05	3	91	2	15735645
Pubmed	Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders.	CFTR NLRP3	2.03e-05	3	91	2	29021150
Pubmed	Interaction of CARD14, SENP1 and VEGFA polymorphisms on susceptibility to high altitude polycythemia in the Han Chinese population at the Qinghai-Tibetan Plateau.	SENP1 CARD14	2.03e-05	3	91	2	26852650
Pubmed	The effects of slow skeletal troponin I expression in the murine myocardium are influenced by development-related shifts in myosin heavy chain isoform.	MYH6 MYH7	2.03e-05	3	91	2	22966157
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	SPTBN4 CDK17 MYH6 EPS15L1 GIT1 PPFIA2 SH3KBP1 MBP MYO18A RAPGEF2 UTRN ARHGAP21 STX1B KNG1	2.06e-05	1431	91	14	37142655
Pubmed	In silico QTL mapping of basal liver iron levels in inbred mouse strains.	AIMP2 N4BP1 EIF2AK1	2.23e-05	21	91	3	21062905
Pubmed	DOT1L regulates dystrophin expression and is critical for cardiac function.	MYH6 MYH7 UTRN	2.23e-05	21	91	3	21289070
Pubmed	AIMP2 promotes TNFalpha-dependent apoptosis via ubiquitin-mediated degradation of TRAF2.	AIMP2 BIRC2	4.05e-05	4	91	2	19584093
Pubmed	Identification of MYO18A as a novel interacting partner of the PAK2/betaPIX/GIT1 complex and its potential function in modulating epithelial cell migration.	GIT1 MYO18A	4.05e-05	4	91	2	19923322
Pubmed	Murine cardiac progenitor cells require visceral embryonic endoderm and primitive streak for terminal differentiation.	MYH6 MYH7	4.05e-05	4	91	2	9389458
Pubmed	Altered cardiac phenotype in transgenic mice carrying the delta337 threonine thyroid hormone receptor beta mutant derived from the S family.	MYH6 MYH7	4.05e-05	4	91	2	9927321
Pubmed	Combined cardiomyocyte PKCδ and PKCε gene deletion uncovers their central role in restraining developmental and reactive heart growth.	MYH6 MYH7	4.05e-05	4	91	2	25900833
Pubmed	Changes in expression of nonmuscle myosin heavy chain isoforms during muscle and nonmuscle tissue development.	MYH6 MYH7	4.05e-05	4	91	2	8482409
Pubmed	Sarcomere protein gene mutations in hypertrophic cardiomyopathy of the elderly.	MYH6 MYH7	4.05e-05	4	91	2	11815426
Pubmed	Androgen receptor is expressed in mouse cardiomyocytes at prenatal and early postnatal developmental stages.	MYH6 MYH7	4.05e-05	4	91	2	28806941
Pubmed	Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling.	GIT1 PPFIA2 MBP MYO18A RAPGEF2	4.37e-05	147	91	5	16959763
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	MYH1 MYH6 MYH7 MDN1 KRT33A ANXA5 CFTR MYO18A LRBA	5.10e-05	647	91	9	26618866
Pubmed	Recruitment of intra- and extracardiac cells into the myocardial lineage during mouse development.	MYH6 MYH7	6.74e-05	5	91	2	12629673
Pubmed	Single-stranded DNA-binding proteins PURalpha and PURbeta bind to a purine-rich negative regulatory element of the alpha-myosin heavy chain gene and control transcriptional and translational regulation of the gene expression. Implications in the repression of alpha-myosin heavy chain during heart failure.	MYH6 MYH7	6.74e-05	5	91	2	12933792
Pubmed	Developmental regulation of myosin gene expression in mouse cardiac muscle.	MYH6 MYH7	6.74e-05	5	91	2	2277065
Pubmed	Mitochondrial fusion directs cardiomyocyte differentiation via calcineurin and Notch signaling.	MYH6 MYH7	6.74e-05	5	91	2	24091702
Pubmed	Enhancer of polycomb1, a novel homeodomain only protein-binding partner, induces skeletal muscle differentiation.	MYH6 MYH7	6.74e-05	5	91	2	17192267
Pubmed	Card10 is a novel caspase recruitment domain/membrane-associated guanylate kinase family member that interacts with BCL10 and activates NF-kappa B.	CARD9 CARD14	6.74e-05	5	91	2	11259443
Pubmed	Myosin heavy chain isoforms of the murine masseter muscle during pre- and post-natal development.	MYH1 MYH7	6.74e-05	5	91	2	12919077
Pubmed	CARD9 negatively regulates NLRP3-induced IL-1β production on Salmonella infection of macrophages.	CARD9 NLRP3	6.74e-05	5	91	2	27670879
Pubmed	Expression of two myogenic regulatory factors myogenin and MyoD1 during mouse embryogenesis.	MYH6 MYH7	6.74e-05	5	91	2	2552320
Pubmed	IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis.	CFTR NLRP3	6.74e-05	5	91	2	26972847
Pubmed	Oxidized Low-Density Lipoprotein Immune Complex Priming of the Nlrp3 Inflammasome Involves TLR and FcγR Cooperation and Is Dependent on CARD9.	CARD9 NLRP3	6.74e-05	5	91	2	28130494
Pubmed	Sox6 is required for normal fiber type differentiation of fetal skeletal muscle in mice.	MYH1 MYH7	6.74e-05	5	91	2	17584907
Pubmed	Genome-wide mapping of Sox6 binding sites in skeletal muscle reveals both direct and indirect regulation of muscle terminal differentiation by Sox6.	MYH1 MYH6 MYH7	7.39e-05	31	91	3	21985497
Pubmed	Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate.	MYH7 KCNQ5 PLXNA2	9.78e-05	34	91	3	31024170
Pubmed	Poly(C)-binding protein 1 (Pcbp1) regulates skeletal muscle differentiation by modulating microRNA processing in myoblasts.	MYH6 MYH7	1.01e-04	6	91	2	28381556
Pubmed	RA-GEF-1 (Rapgef2) is essential for proper development of the midline commissures.	MBP RAPGEF2	1.01e-04	6	91	2	21864586
Pubmed	Distinct myogenic programs of embryonic and fetal mouse muscle cells: expression of the perinatal myosin heavy chain isoform in vitro.	MYH1 MYH7	1.01e-04	6	91	2	1728586
Pubmed	Loss of the neurodevelopmental Joubert syndrome causing protein, Ahi1, causes motor and muscle development delays independent of central nervous system involvement.	MYH7 MBP	1.01e-04	6	91	2	30695685
Pubmed	Spatial and temporal changes in myosin heavy chain gene expression in skeletal muscle development.	MYH1 MYH7	1.01e-04	6	91	2	10588881
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	EPS15L1 SH3KBP1 PPP1R37 N4BP1 JPT1 ARHGEF16 UTRN ARHGAP21	1.20e-04	565	91	8	25468996
Pubmed	Myosin regulatory light chains are required to maintain the stability of myosin II and cellular integrity.	MYH6 MYH7	1.41e-04	7	91	2	21126233
Pubmed	Novel roles of cardiac-derived erythropoietin in cardiac development and function.	MYH6 MYH7	1.41e-04	7	91	2	38382296
Pubmed	Differentiation and integrity of cardiac muscle cells are impaired in the absence of beta 1 integrin.	MYH6 MYH7	1.41e-04	7	91	2	9004034
Pubmed	A fast Myosin super enhancer dictates muscle fiber phenotype through competitive interactions with Myosin genes.	MYH1 MYH7	1.41e-04	7	91	2	35210422
Pubmed	ANKK1 is found in myogenic precursors and muscle fibers subtypes with glycolytic metabolism.	MYH1 MYH7	1.41e-04	7	91	2	29758057
Interaction	KRT78 interactions	KRT31 KRT32 CFTR NUMA1 QSER1 WTAP	2.22e-06	87	88	6	int:KRT78
Interaction	BICDL2 interactions	CDK17 CARD9 CFTR	9.44e-06	10	88	3	int:BICDL2
GeneFamily	Myosin heavy chains	MYH1 MYH6 MYH7	1.39e-05	15	58	3	1098
GeneFamily	Keratins, type I	KRT31 KRT32 KRT33A	9.69e-05	28	58	3	608
GeneFamily	WD repeat domain containing\|Caspase recruitment domain containing\|Apoptosome	CARD9 BIRC2 CARD14	1.20e-04	30	58	3	959
GeneFamily	PDZ domain containing	MYO18A RAPGEF2 ARHGAP21 CARD14 PDZRN4	1.26e-04	152	58	5	1220
GeneFamily	ATP binding cassette subfamily C	CFTR ABCC10	7.71e-04	13	58	2	807
GeneFamily	Fibronectin type III domain containing	BOC FSD1 PTPRU CMYA5	1.73e-03	160	58	4	555
GeneFamily	Ring finger proteins\|Fanconi anemia complementation groups\|Protein phosphatase 1 regulatory subunits\|BRCA1 A complex\|BRCA1 B complex\|BRCA1 C complex	FANCG SLX4	1.85e-03	20	58	2	548
GeneFamily	NLR family	NLRP9 NLRP3	2.89e-03	25	58	2	666
GeneFamily	Pyrin domain containing\|Pyrin and HIN domain family	NLRP9 NLRP3	2.89e-03	25	58	2	994
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	SPTBN4 ROCK1 ARHGEF16 ARHGAP21	4.30e-03	206	58	4	682
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	ARHGAP6 ARHGAP21	1.12e-02	50	58	2	721
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#3	GCC2 ANKIB1 BIRC2 ROCK1 N4BP1 LRBA KIF20B SLX4 PLXNA2	4.03e-06	291	90	9	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000_K3
ToppCell	RA-13._Vascular_Smooth_Muscle\|RA / Chamber and Cluster_Paper	PRUNE2 ARHGAP6 KCNQ5 PPFIA2 ROCK1 PDZRN4	2.09e-06	183	91	6	818fd886e0188091310825f9145fa53328f2c979
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SPTBN4 ARHGAP6 PPFIA2 RP1 LRBA KNG1	2.15e-06	184	91	6	e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-IPC/newborn-38\|World / Primary Cells by Cluster	CCDC88C ROCK1 QSER1 SSTR2 ARHGAP21 PLXNA2	3.10e-06	196	91	6	38da0751941adca650fe9b383d9f343153978eb5
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-IPC/newborn\|World / Primary Cells by Cluster	CCDC88C ROCK1 QSER1 SSTR2 ARHGAP21 PLXNA2	3.10e-06	196	91	6	721650a08d260faf530dbd52d4e9275d27f3bac2
ToppCell	COVID-19-kidney-AQP1+PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	BOC CDK17 PLVAP ADGRB3 UTRN PLXNA2	3.29e-06	198	91	6	8689090bce9ab6e8f122426a404037e572c6713b
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GIT1 PPRC1 JAKMIP1 KIF20B ABCC10	1.38e-05	149	91	5	3378d0fe79de6d7879fd48717ded5027593c785f
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	JAKMIP1 LRBA SLX4 KNG1 ABCC10	1.88e-05	159	91	5	03d77e7fee40262bf0942aab96b273f1c4f5d8e3
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIA2 CFTR RXFP2 SYCP1 PDZRN4	1.94e-05	160	91	5	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP6 PPFIA2 SCTR RP1 KNG1	1.94e-05	160	91	5	03b88dc7ad41c6ae443cab7e77ec666340bf432e
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIA2 CFTR RXFP2 SYCP1 PDZRN4	1.94e-05	160	91	5	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	droplet-Marrow-BM-30m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCAF1 AP5Z1 LRBA NLRP3 ABCB4	2.06e-05	162	91	5	75df7ff779a3b9159ba97d852da1f8df650b9ce5
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_ETV4\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYH1 KRT31 KRT32 CFTR PDZRN4	2.25e-05	165	91	5	1121f78574b9fe64d966b7f8c9cbc4d59e9b6e5e
ToppCell	droplet-Liver-LIVER-NPC-1m-Lymphocytic-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FANCG KCNQ5 JAKMIP1 KIF20B NCBP3	2.25e-05	165	91	5	8c7a6f9e2ca0ce077426d3d0726e3f5a4c03b296
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP6 SCTR RP1 LRBA KNG1	2.98e-05	175	91	5	e5467dacf81f1f913b1719931cf1a7331434a7e7
ToppCell	E18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SYCP1 MAP4K2 SLX4 PLXNA2 ABCC10	2.98e-05	175	91	5	711ace94fa9a763c6ae48171a690953f25deebe4
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	BOC PRUNE2 ARHGAP6 KCNQ5 ADGRB3	3.15e-05	177	91	5	b59967219f7d874805768e247c0eb2bc4d4420c8
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARHGAP6 RXFP2 PTPRU SSTR2 PDZRN4	3.32e-05	179	91	5	f65889bf1e41396979cce44a5e63f49dea2bbd9b
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP6 PPFIA2 RP1 LRBA KNG1	3.69e-05	183	91	5	31ab55d5f3639f5964541d5eae23044dbda3356e
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BOC CDK17 PLVAP ADGRB3 PLXNA2	3.69e-05	183	91	5	dc19857b66dcadbf7c87de91f7b1f4e8ef2857ed
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BOC CDK17 PLVAP ADGRB3 PLXNA2	3.69e-05	183	91	5	4759560e5b4f4e5a00e5f933e3451a27c7c4aefe
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARHGAP6 RXFP2 PTPRU SSTR2 PDZRN4	3.69e-05	183	91	5	65f2a5895d166189a095cf7ea9dda171f0419b08
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP6 PPFIA2 RP1 LRBA KNG1	3.89e-05	185	91	5	898a093757f86be3e18d2ef1f16a71f50ef81dc3
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP6 PPFIA2 RP1 LRBA KNG1	4.09e-05	187	91	5	b93cf4dfe8ffb89348ee7bccc9f284189f7240a2
ToppCell	COVID-19-Heart-EC_2\|Heart / Disease (COVID-19 only), tissue and cell type	CCDC88C CDK17 RAPGEF2 UTRN PLXNA2	4.09e-05	187	91	5	40ffc06a3e3251d9b12da390210d3e045af7537a
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	PRUNE2 KCNQ5 PPFIA2 ROCK1 PDZRN4	4.20e-05	188	91	5	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP6 PPFIA2 RP1 LRBA KNG1	4.31e-05	189	91	5	f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH6 MYH7 RP1 CMYA5 PDZRN4	4.31e-05	189	91	5	e758b264c0a47127e33e66c395cf5a3224c7305b
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	PRUNE2 KCNQ5 PPFIA2 ROCK1 PDZRN4	4.31e-05	189	91	5	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH6 MYH7 RP1 CMYA5 PDZRN4	4.31e-05	189	91	5	b98f60875b1a12b2ec9dc91889298ae57f98602f
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC88C KRT32 MBP PTPRU PDZRN4	4.31e-05	189	91	5	38acb307907fde68b992057714448c1561d69ee3
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KCNQ5 CARD9 PPFIA2 RETREG1 SSTR2	4.41e-05	190	91	5	7e4d80a3a7f83b6a50f1d0fe82fb6c242c39d5b0
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGAP6 KCNQ5 CARD9 RETREG1 SSTR2	4.41e-05	190	91	5	1004e89d99c9d46c78b7d3532d8d4aadb81a96fd
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP6 PPFIA2 RP1 LRBA KNG1	4.41e-05	190	91	5	b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KCNQ5 CARD9 PPFIA2 RETREG1 SSTR2	4.41e-05	190	91	5	7fec459cd2ad12c2923a03d098289337c0a4c1d3
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP6 PPFIA2 RP1 LRBA KNG1	4.53e-05	191	91	5	963f4f2e852bbb4faf070aafb0d368297abacd3b
ToppCell	P07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KCNQ5 CARD9 RETREG1 RAPGEF2 SSTR2	4.53e-05	191	91	5	2ad717b59215ad8d933e9637d363b65d7298e5d4
ToppCell	PND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGAP6 KCNQ5 CARD9 RETREG1 SSTR2	4.64e-05	192	91	5	158cc5736f154da1cb3186ffbf186eae10483e48
ToppCell	PND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGAP6 KCNQ5 CARD9 RETREG1 SSTR2	4.64e-05	192	91	5	f4ff62ac9c53eafbe917706de9af8b2d4bded4d4
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	BOC CDK17 PLVAP ADGRB3 PLXNA2	4.99e-05	195	91	5	818bc18c5834238e5f733cac6fe928ed0788f57d
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	BOC CDK17 PLVAP ADGRB3 PLXNA2	5.12e-05	196	91	5	7cbb19108b4553ef60ef5c230a29de1662c02efe
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	BOC CDK17 PLVAP ADGRB3 PLXNA2	5.12e-05	196	91	5	4cd1e6b7a791e11a40b19f971b7011bd11fe6273
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	BOC CDK17 PLVAP ADGRB3 PLXNA2	5.12e-05	196	91	5	d37f714d4fb57e958f3738fdda085560813e5bb5
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BOC PRUNE2 LUZP4 KCNQ5 PDZRN4	5.12e-05	196	91	5	9830fb3da7a60f65ad463e9054bb77c06b025e4d
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CDK17 PLVAP ADGRB3 UTRN PLXNA2	5.12e-05	196	91	5	e224338490691d92c1f70b57112fabdcc92b06a9
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CDK17 PLVAP ADGRB3 UTRN PLXNA2	5.24e-05	197	91	5	c10dd1aaec01fb662eac83dfde90e3e426665d65
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CDK17 PLVAP ADGRB3 UTRN PLXNA2	5.24e-05	197	91	5	2844dbcd0a673ed81c99920aa45858651a00736d
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	NBAS ADGRB3 LRBA RAPGEF2 UTRN	5.50e-05	199	91	5	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	mild-CD8+_Tem\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CCDC88C MBP N4BP1 JAKMIP1 UTRN	5.63e-05	200	91	5	d8aec4904c9420b8f9d7508658ba1e36c66cdfcc
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ARHGAP6 GIT1 GCC2 RETREG1 MAP4K2	5.63e-05	200	91	5	7034f57e282982c19c13ee8ab78eabaffa069e30
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-cortical_neurons_2\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	PPFIA2 ABHD6 JAKMIP1 SSTR2 PLXNA2	5.63e-05	200	91	5	0cb0755a101ec655359d051d6a8807408d727c55
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Myh4\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MYH1 KRT32 PTPRU UTRN	1.42e-04	129	91	4	f83187c0bb06528127b8d2d56674ab1946846951
ToppCell	facs-Marrow-B-cells-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH1 MYH7 KRT32 PDZRN4	1.79e-04	137	91	4	4dcb15de821439011df1bb0bbd7682d674bd725d
ToppCell	facs-Marrow-B-cells-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH1 MYH7 KRT32 PDZRN4	1.79e-04	137	91	4	c05ceeb7b483324604cb3f647d2da2b3786071b1
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Gkn1_Pcdh19\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MYH7 RXFP2 MBP SSTR2	2.17e-04	144	91	4	e8caeb6485f4c8f9a3384570dc69024c2bcc9ab0
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1\|Striatum / BrainAtlas - Mouse McCarroll V32	CDK17 KCNQ5 CFTR ABCC10	2.28e-04	146	91	4	7b863f9bc63dc1afe015a18a70cd6ed0b71d1f09
ToppCell	Influenza_Severe-CD4+_T_naive\|World / Disease group and Cell class	NLRP9 RETREG1 STX1B MYO16	2.47e-04	149	91	4	ce6552063510aa3e0b9d6e5b531eea67410e7056
ToppCell	COVID-19-Epithelial_cells-Airway_mucous\|COVID-19 / group, cell type (main and fine annotations)	ADGB KRT32 SPEF2 RP1	2.60e-04	151	91	4	8216462e723fec2797387929dde095370947e10a
ToppCell	ASK454-Epithelial-Type_2\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	CFTR NCBP3	2.64e-04	12	91	2	f8ea75314b9fa2bdc57564cad9640893a47f0340
ToppCell	PND01-03-samps-Mesenchymal-Pericyte\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	KCNQ5 CARD9 PPFIA2 SSTR2	2.66e-04	152	91	4	fc9472bc19f997103da535b035105f01429cb08e
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SCTR CMYA5 CCDC136 KNG1	2.73e-04	153	91	4	0727dc70e16345645063c586d744bc4ac1710526
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFTR RXFP2 FSD1 PDZRN4	2.80e-04	154	91	4	1e32969bee810adaf2d560f0824a16227df513d8
ToppCell	LPS-IL1RA+antiTNF-Unknown-Endothelial-Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRUNE2 MDN1 CEP131 CCDC136	2.80e-04	154	91	4	16fdafb5c64d2db321554f87129a962d113f1668
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Batf3\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	BOC KCNQ5 SSTR2 UTRN	3.01e-04	157	91	4	921805932f7974d37aed547861d555b07f30aba6
ToppCell	facs-Trachea-nan-3m-Myeloid-lymphocyte_of_B_lineage\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAKMIP1 MAP4K2 KIF20B ABCB4	3.01e-04	157	91	4	0fecc14959c4c9efc19d5c06475a890e0a30f148
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BOC KCNQ5 SH3KBP1 JAKMIP1	3.16e-04	159	91	4	d3f81ba22160568ccaa6d2b04ebfd30630f9a6db
ToppCell	P15-Epithelial-epithelial_progenitor_cell-epi_progenitor\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MYH7 PPFIA2 CFTR ARHGEF16	3.16e-04	159	91	4	a4bfd59c53237964fc24a24de5c1925fdd01db99
ToppCell	Hippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Grp_(Neuron.Slc17a6.Grp)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	MYH1 MYH6 SYCP1	3.19e-04	65	91	3	b7bc23af54d6d2f7afd584f4df42c24d7c49e344
ToppCell	Hippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Grp_(Neuron.Slc17a6.Grp)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	MYH1 MYH6 SYCP1	3.19e-04	65	91	3	3b3630253f5713c4a688c74c4ea0f98c1fe42594
ToppCell	RV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	PRUNE2 PPFIA2 UTRN PDZRN4	3.24e-04	160	91	4	29c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCell	Adult-Mesenchymal-myofibroblast_cell-D175\|Adult / Lineage, Cell type, age group and donor	SPTBN4 FANCG ADGRB3 CCDC136	3.31e-04	161	91	4	048b7dc00746987a24bf870d4d278c4183eb04a2
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	BOC JPT1 SSTR2 CARD14	3.31e-04	161	91	4	bd520c9a1927d5d5355b4421e6b90b58bfb76a42
ToppCell	RV-13._Vascular_Smooth_Muscle\|RV / Chamber and Cluster_Paper	PRUNE2 PPFIA2 UTRN PDZRN4	3.31e-04	161	91	4	47b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCell	facs-SCAT-Fat-24m\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH6 MBP CCDC136 KNG1	3.39e-04	162	91	4	b824f30c723c9c7d8e8c8a8dc3f88d4eed29dd67
ToppCell	390C-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ARHGAP6 SPEF2 TUT7 MYO18A	3.39e-04	162	91	4	45be019b50e3727fc9d3fad2ff78e74e4f2d746b
ToppCell	390C-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ARHGAP6 SPEF2 TUT7 MYO18A	3.39e-04	162	91	4	fbb0cc2b1434a340dc35058b77c73ea61004c252
ToppCell	Ciliated_cells-A-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	ADGB SPEF2 RP1 LGSN	3.47e-04	163	91	4	43194c6127df1ce3d29242f719645de3c11fd7c0
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal-Cilia-bearing_cell\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	VANGL1 SPEF2 CCDC62 TMEM191C	3.55e-04	164	91	4	346e1530b4bf30adbcb2f7d64fdfb4cd8df69d7f
ToppCell	356C-Epithelial_cells-Epithelial-D_(AT2)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	CFTR SCTR PTPRU SLX4	3.72e-04	166	91	4	2e4cb4056e6b0c43290a5588ff525f5f05b8beee
ToppCell	356C-Epithelial_cells-Epithelial-D_(AT2)\|356C / Donor, Lineage, Cell class and subclass (all cells)	CFTR SCTR PTPRU SLX4	3.72e-04	166	91	4	eb8d972326a734549675307e411fc795af66da70
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_SLITRK6\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARHGAP6 ANXA5 UTRN PDZRN4	3.98e-04	169	91	4	1c9e54e7b14eb99996590fb93b257cf881a9f184
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADGB CCDC88C SPEF2 RP1	3.98e-04	169	91	4	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	COVID-19-Heart-CM_+_Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYH6 MYH7 EMC10 CMYA5	4.07e-04	170	91	4	3f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYH7 KCNQ5 SCTR PDZRN4	4.07e-04	170	91	4	99dd734c0972a40d5381e8e2d96bdaa31f6d06e6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYH7 KCNQ5 SCTR PDZRN4	4.07e-04	170	91	4	3a14eeae221b8bb0bd0dadcb8e7a603431240a1e
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARHGAP6 CFTR PTPRU PDZRN4	4.07e-04	170	91	4	417b77c12a7982b1ce4b4bc57f30335d261220f5
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYH7 KCNQ5 SCTR PDZRN4	4.07e-04	170	91	4	cdb6fad277f284c3fd5a6f45672a8edc24715882
ToppCell	LV-13._Vascular_Smooth_Muscle\|LV / Chamber and Cluster_Paper	PRUNE2 ROCK1 UTRN PDZRN4	4.16e-04	171	91	4	e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Deuterosomal\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ADGB MYH7 SYCP1 CEP43	4.16e-04	171	91	4	52aec5f6677fe2f7a36fb5b18117a4cffaeff58f
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH6 MYH7 RP1 CMYA5	4.25e-04	172	91	4	ee8ce9e8c9a6d3ee2be113f77743958005f4b3f0
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_D\|367C / Donor, Lineage, Cell class and subclass (all cells)	CCDC88C TMEM191C FSD1 CCDC136	4.25e-04	172	91	4	6379ae0aca9007c3a8a87e3330908fc90961ad3f
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_CPZ\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARHGAP6 MYH1 KRT31 PDZRN4	4.25e-04	172	91	4	1cfea985c5959b38beea351b892cd5e92e27f927
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH6 MYH7 RP1 CMYA5	4.25e-04	172	91	4	bd468a7ea6ec832dcf6a816a1e0c03fa0f176dad
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SPEF2 ANXA5 SSTR2 PDZRN4	4.44e-04	174	91	4	bc978a2148a0261a4f9d1ca5479b707e224566be
ToppCell	356C-Myeloid-Macrophage-SPP1+_Macrophage_4\|356C / Donor, Lineage, Cell class and subclass (all cells)	ADGB ANXA5 CCDC62 SLX4	4.44e-04	174	91	4	75b3a852140fb726025c3c987143d67944afde2d
ToppCell	PND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KCNQ5 PPFIA2 CCDC136 ABCB4	4.54e-04	175	91	4	8362a46f5804333baa84cd56d450bc147f372a7e
ToppCell	PND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KCNQ5 PPFIA2 CCDC136 ABCB4	4.54e-04	175	91	4	8b4c62e608f0ec84e563bbf0ebffe3ed44085298
ToppCell	droplet-Fat-Mat-18m-Hematologic-monocyte\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNQ5 JAKMIP1 ABCC10 NLRP3	4.64e-04	176	91	4	867936a20f73f638055c19c8d88834aa2cc657cf
ToppCell	COVID-19-Heart-CM_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYH6 MYH7 EMC10 CMYA5	4.64e-04	176	91	4	9df7a124ebafb0087da0cda133a394275d7bed81
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH6 PSME4 CMYA5 ARHGAP21	4.64e-04	176	91	4	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADGB SPEF2 RP1 LGSN	4.64e-04	176	91	4	dee780cfa85234a7cd7bf440b66b84cec959893e
Drug	blebbistatin	MYH1 MYH6 MYH7 MYO18A ROCK1 ABCB4	6.32e-06	116	89	6	CID003476986
Drug	NSC605986	CFTR MBP ABHD6	9.31e-06	11	89	3	CID000354376
Drug	geldanamycin; Down 200; 1uM; MCF7; HT_HG-U133A_EA	PPRC1 AP5Z1 ABHD6 RETREG1 PTPRU EIF2AK1 CEP43	1.01e-05	191	89	7	1008_DN
Disease	dilated cardiomyopathy 1S (implicated_via_orthology)	MYH1 MYH6 MYH7	3.13e-06	10	89	3	DOID:0110454 (implicated_via_orthology)
Disease	autosomal dominant hyaline body myopathy (implicated_via_orthology)	MYH1 MYH6 MYH7	3.13e-06	10	89	3	DOID:0111269 (implicated_via_orthology)
Disease	congenital myopathy 6 (implicated_via_orthology)	MYH1 MYH6 MYH7	3.13e-06	10	89	3	DOID:0080719 (implicated_via_orthology)
Disease	distal arthrogryposis type 2B3 (implicated_via_orthology)	MYH1 MYH6 MYH7	3.13e-06	10	89	3	DOID:0111602 (implicated_via_orthology)
Disease	inclusion body myositis (implicated_via_orthology)	MYH1 MYH6 MYH7	3.13e-06	10	89	3	DOID:3429 (implicated_via_orthology)
Disease	distal arthrogryposis type 2A (implicated_via_orthology)	MYH1 MYH6 MYH7	3.13e-06	10	89	3	DOID:0111605 (implicated_via_orthology)
Disease	familial hypertrophic cardiomyopathy (implicated_via_orthology)	MYH1 MYH6 MYH7	3.13e-06	10	89	3	DOID:0080326 (implicated_via_orthology)
Disease	distal arthrogryposis type 1 (implicated_via_orthology)	MYH1 MYH6 MYH7	3.13e-06	10	89	3	DOID:0111596 (implicated_via_orthology)
Disease	distal myopathy (implicated_via_orthology)	MYH1 MYH6 MYH7	5.72e-06	12	89	3	DOID:11720 (implicated_via_orthology)
Disease	myotonia congenita (implicated_via_orthology)	MYH1 MYH6 MYH7	5.72e-06	12	89	3	DOID:2106 (implicated_via_orthology)
Disease	restrictive cardiomyopathy (implicated_via_orthology)	MYH1 MYH6 MYH7	7.42e-06	13	89	3	DOID:397 (implicated_via_orthology)
Disease	distal arthrogryposis (implicated_via_orthology)	MYH1 MYH6 MYH7	1.18e-05	15	89	3	DOID:0050646 (implicated_via_orthology)
Disease	Caveolinopathy	MYH6 MYH7	5.38e-05	4	89	2	cv:C5679790
Disease	CARDIOMYOPATHY, FAMILIAL HYPERTROPHIC, 1	MYH6 MYH7	5.38e-05	4	89	2	192600
Disease	anaphylaxis	KNG1 NLRP3	5.38e-05	4	89	2	C0002792
Disease	Cardiomyopathy, Familial Hypertrophic, 1 (disorder)	MYH6 MYH7	5.38e-05	4	89	2	C3495498
Disease	Hypertrophic cardiomyopathy 1	MYH6 MYH7	5.38e-05	4	89	2	cv:C3495498
Disease	hypothyroidism (biomarker_via_orthology)	MYH6 MYH7 ANXA5 MBP	1.03e-04	80	89	4	DOID:1459 (biomarker_via_orthology)
Disease	Idiopathic hypertrophic subaortic stenosis	MYH6 MYH7	1.87e-04	7	89	2	C0700053
Disease	Obstructive asymmetric septal hypertrophy	MYH6 MYH7	1.87e-04	7	89	2	C0597124
Disease	Colorectal Carcinoma	BOC FANCG KCNQ5 CCDC62 CFTR JAKMIP1 PTPRU ABCB4 PDZRN4	2.71e-04	702	89	9	C0009402
Disease	Hypermetropia	CCDC88C KCNQ5 PTPRU ARHGAP21	2.72e-04	103	89	4	HP_0000540
Disease	Cardiomyopathy, Hypertrophic, Familial	MYH6 MYH7	3.19e-04	9	89	2	C0949658
Disease	cystic fibrosis (implicated_via_orthology)	CFTR ABCB4	3.19e-04	9	89	2	DOID:1485 (implicated_via_orthology)
Disease	Muscular dystrophy, limb-girdle, autosomal dominant	MYH6 MYH7	3.98e-04	10	89	2	cv:C5675009
Disease	long QT syndrome (implicated_via_orthology)	ARHGAP6 KCNQ5	3.98e-04	10	89	2	DOID:2843 (implicated_via_orthology)
Disease	myopathy (implicated_via_orthology)	MYH1 MYH6 MYH7	4.16e-04	48	89	3	DOID:423 (implicated_via_orthology)
Disease	Fanconi anemia	FANCG SLX4	8.00e-04	14	89	2	cv:C0015625
Disease	alkaline phosphatase measurement	GCC2 PPP1R37 RP1 LRBA UTRN MAP4K2 ARHGAP21 ABCC10 NLRP3 PDZRN4	9.66e-04	1015	89	10	EFO_0004533
Disease	cardiomyopathy (implicated_via_orthology)	MYH1 MYH6 MYH7	1.31e-03	71	89	3	DOID:0050700 (implicated_via_orthology)
Disease	Bone marrow hypocellularity	FANCG SLX4	1.33e-03	18	89	2	C1855710
Disease	myocardial infarction (biomarker_via_orthology)	MYH6 MYH7 ANXA5 NLRP3	1.42e-03	160	89	4	DOID:5844 (biomarker_via_orthology)
Disease	electroencephalogram measurement	ANXA5 CMYA5 MYO16	1.47e-03	74	89	3	EFO_0004357
Disease	Cholecystitis	LRBA ABCB4	1.49e-03	19	89	2	HP_0001082
Disease	dilated cardiomyopathy (implicated_via_orthology)	MYH1 MYH6 MYH7	1.84e-03	80	89	3	DOID:12930 (implicated_via_orthology)
Disease	Primary familial hypertrophic cardiomyopathy	MYH6 MYH7	2.00e-03	22	89	2	cv:C0949658
Disease	Hypertrophic obstructive cardiomyopathy	MYH6 MYH7	2.58e-03	25	89	2	C4551472
Disease	Fanconi Anemia	FANCG SLX4	2.58e-03	25	89	2	C0015625
Disease	Pancytopenia	FANCG SLX4	2.79e-03	26	89	2	C0030312
Disease	Acute monocytic leukemia	FANCG SLX4	2.79e-03	26	89	2	C0023465
Disease	primary aldosteronism	RXFP2 ADGRB3	2.79e-03	26	89	2	MONDO_0001422
Disease	Limb-girdle muscular dystrophy	MYH6 MYH7	2.79e-03	26	89	2	cv:C0686353

Protein segments in the cluster

Peptide	Gene	Start	Entry
LLGNDSTRTEEVQDD	VANGL1	56	Q8TAA9
TTRSSLDDLSIDGQV	ABHD6	111	Q9BV23
NDLDRETSSLQELEA	EPS15L1	426	Q9UBC2
RLSQETGLEISEEIN	CFTR	811	P13569
LLSEDLEARNETLSN	CCDC62	126	Q6P9F0
SDGLNLEREIVSQTT	ADGB	596	Q8N7X0
TITGTLSRISLNDDE	ADGRB3	1211	O60242
ERGLNTSQESDDDIL	ARHGEF16	221	Q5VV41
QLSLQESGLALDEET	ANKIB1	861	Q9P2G1
NLELSLRSQSDLDDQ	GIT1	366	Q9Y2X7
LDTDDRSEQEGSTLS	AP5Z1	261	O43299
IEETIDRETSGNLEQ	ANXA5	221	P08758
QQLETLVLSSDLEDG	CARD9	416	Q9H257
GRTDESLRNDESSEQ	PDZRN4	556	Q6ZMN7
ASLESSTQRLSDGEI	QSER1	576	Q2KHR3
RSRSQGDLVDTQSDL	LUZP4	231	Q9P127
LTDRENQSILITGES	MYH7	166	P12883
GRSLDTNEVTQEITD	MAP4K2	766	Q12851
GLEEEQSTSGRLLQE	ABCC10	846	Q5T3U5
SSQLQTGRDLEDEVV	MDN1	3271	Q9NU22
NLRDSLENTLTESEA	KRT31	291	Q15323
IQDDASTGERSLNRE	MYO16	626	Q9Y6X6
LESSEELLETANQTL	FSD1	91	Q9BTV5
SLRDSLENTLTESEA	KRT32	331	Q14532
IRSTEELNIQLSGSE	KCNQ5	836	Q9NR82
NRELLLQEDDSGSDT	CCDC88C	941	Q9P219
TESNLQATERRAEGL	PLVAP	56	Q9BX97
LQTDINELTSDLDRS	PLXNA2	1296	O75051
ISELTSELTDERNTG	MYO18A	1291	Q92614
RENESDSLIQELETS	KIF20B	741	Q96Q89
DTLSQVEEESLLRND	NCBP3	231	Q53F19
DLESSGLQRRNSSEA	JPT1	76	Q9UK76
NLRDSLENTLTESEA	KRT33A	291	O76009
EGTLEETLTNETRNA	LRBA	1031	P50851
EGRASSTTLEDLESQ	GOLGA6L3	76	A6NEY3
EGRASSTTLEDLESQ	GOLGA6L4	76	A6NEF3
TSLNDLSLTRDEQEI	JAKMIP1	381	Q96N16
DLTAQRARLQTESGE	MYH1	1276	P12882
TLRGSQTIDESLSEL	CDK17	11	Q00537
QQLGDTTAELESLEL	FANCG	291	O15287
DSGLSTLEIENRAQD	NBAS	1711	A2RRP1
DINDTTELNTRLTDD	ABCB4	166	P21439
TDQSTLQEDERLGLS	PTPRU	811	Q92729
EELLLEASQESGQET	PPP1R37	676	O75864
SITDLDDNQSRLLEA	ARHGAP6	366	O43182
LSNLLIDTTSEEDSG	BOC	281	Q9BWV1
LRTASDQESGDEELN	CARD14	251	Q9BXL6
LDDLTQDLTVSQLSD	CEP43	376	O95684
SGELESTLELQENGL	EIF2AK1	316	Q9BQI3
ESLLSEGRLDTSVQT	LINC00322	41	Q6ZN03
AISELSSLLREESQN	CMYA5	1696	Q8N3K9
SDNEDLLARIETLQS	GCC2	1066	Q8IWJ2
NLGELSRTTSEDNEV	MBP	31	P02686
SRLLLSLTQESQSEE	KNG1	11	P01042
GTLSLSQRQLSEEER	EMC10	81	Q5UCC4
LSEDTLTEATLQGRN	C9orf40	171	Q8IXQ3
DLNSNDVTGLRESEE	WTAP	46	Q15007
ERSLLVSTDEGNENS	HELZ2	2476	Q9BYK8
AELEELRQQLEESSS	CEP131	816	Q9UPN4
SLGESRLSLEDQNEV	PPRC1	111	Q5VV67
LDTLRETQESLSLAQ	PPFIA2	46	O75334
DLLQEDSTRDEGNET	LGSN	6	Q5TDP6
SRAERDSALETLQGQ	NUMA1	1156	Q14980
ILNLTDLESSREQED	RP1	2141	P56715
QSLTELDLSDNSLGD	NLRP3	741	Q96P20
STTELGENLQELRDL	UTRN	2111	P46939
DGTLTIEQLDSLRDQ	SPEF2	1461	Q9C093
RELSDSSGVLEINSS	PRUNE2	1846	Q8WUY3
AESESLNQRLQDLSE	TMEM191B	81	P0C7N4
AESESLNQRLQDLSE	TMEM191C	81	A6NGB0
SELDQIESELGLTQD	RETREG1	461	Q9H6L5
QDEQLSKSSLRETTG	SH3KBP1	166	Q96B97
EDQLSLSDQQILSSR	SENP1	36	Q9P0U3
NLGELDLSSNTITEL	RXFP2	306	Q8WXD0
LTDRENQSILITGES	MYH6	166	P13533
NETTETQRTLLNGDL	SSTR2	351	P30874
LLVQDSETTGRQIED	SLX4	471	Q8IY92
LEQLLSTSDTTGEEN	BIRC2	356	Q13490
EESNLSLQALESRQD	AIMP2	46	Q13155
TGQLADLESERTQRA	CCDC136	251	Q96JN2
LERGEDLEINSQNTT	NLRP9	351	Q7RTR0
TEELSQDQGDRASLD	RAPGEF2	1226	Q9Y4G8
EEEGLSQSISRISET	SCAF1	286	Q9H7N4
EQSSLRASLEIELSN	SYCP1	741	Q15431
QLEITGRTTTNEELE	STX1B	151	P61266
LQELSREQTGDLGTE	SCTR	46	P47872
LQSRELGSSVDEVEQ	SPTBN4	2071	Q9H254
GLIESSTLEQTREET	PSME4	556	Q14997
QLEEANDLLRTESDT	ROCK1	546	Q13464
GSTRNNESESTLDLE	TUT7	776	Q5VYS8
LNEEDTGVTNRDLIS	ARHGAP21	1041	Q5T5U3
TGLNISRDETVLQEE	N4BP1	221	O75113