Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	Helicase_C	SMARCAL1 ASCC3	8.27e-03	107	24	2	PF00271
Domain	HELICc	SMARCAL1 ASCC3	8.27e-03	107	24	2	SM00490
Domain	Helicase_C	SMARCAL1 ASCC3	8.42e-03	108	24	2	IPR001650
Domain	HELICASE_CTER	SMARCAL1 ASCC3	8.57e-03	109	24	2	PS51194
Domain	HELICASE_ATP_BIND_1	SMARCAL1 ASCC3	8.57e-03	109	24	2	PS51192
Domain	DEXDc	SMARCAL1 ASCC3	8.57e-03	109	24	2	SM00487
Domain	Helicase_ATP-bd	SMARCAL1 ASCC3	8.72e-03	110	24	2	IPR014001
Domain	-	RAB11FIP5 ASCC3	1.54e-02	148	24	2	2.60.40.150
Pathway	REACTOME_DNA_DAMAGE_REVERSAL	ALKBH3 ASCC3	5.89e-05	8	21	2	M27702
Pubmed	ALKBH3 partner ASCC3 mediates P-body formation and selective clearance of MMS-induced 1-methyladenosine and 3-methylcytosine from mRNA.	ALKBH3 ASCC3	4.56e-07	2	24	2	34217309
Pubmed	DNA unwinding by ASCC3 helicase is coupled to ALKBH3-dependent DNA alkylation repair and cancer cell proliferation.	ALKBH3 ASCC3	4.56e-07	2	24	2	22055184
Pubmed	Conserved beta-hairpin recognition by the GYF domains of Smy2 and GIGYF2 in mRNA surveillance and vesicular transport complexes.	GEMIN4 TNRC6B	1.14e-04	23	24	2	20696395
Pubmed	A single-cell time-lapse of mouse prenatal development from gastrula to birth.	SIX2 RELN	1.36e-04	25	24	2	38355799
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	GEMIN4 TNRC6B UBR4 ASCC3	1.81e-04	418	24	4	34709266
Pubmed	A possible mechanism behind autoimmune disorders discovered by genome-wide linkage and association analysis in celiac disease.	KLK2 HYDIN	2.68e-04	35	24	2	23936387
Pubmed	Noncanonical regulation of alkylation damage resistance by the OTUD4 deubiquitinase.	ALKBH3 ASCC3	3.33e-04	39	24	2	25944111
Pubmed	Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators.	STEAP1B RELN	3.86e-04	42	24	2	23863479
Pubmed	The FOXG1/FOXO/SMAD network balances proliferation and differentiation of cortical progenitors and activates Kcnh3 expression in mature neurons.	PARP4 RELN	4.24e-04	44	24	2	27224923
Pubmed	PLK4 deubiquitination by Spata2-CYLD suppresses NEK7-mediated NLRP3 inflammasome activation at the centrosome.	TNRC6B A3GALT2	5.26e-04	49	24	2	31762063
Disease	celiac disease	KLK2 HYDIN	4.70e-03	126	24	2	EFO_0001060
Disease	bitter alcoholic beverage consumption measurement	TNRC6B RELN	5.22e-03	133	24	2	EFO_0010092
Disease	chronotype measurement	ALKBH3 PPP2R2D TNRC6B RELN	5.23e-03	882	24	4	EFO_0008328
Disease	ascending aortic diameter	TNRC6B HYDIN	5.76e-03	140	24	2	EFO_0021787

Protein segments in the cluster

Peptide	Gene	Start	Entry
KSHLHQKPGQTWKNK	ALKBH3	31	Q96Q83
QKPGQTWKNKEHHLS	ALKBH3	36	Q96Q83
FNKKILHTAWHPVDN	PPP2R2D	421	Q66LE6
QHTQWYKLHSKPGKK	RAB11FIP5	141	Q9BXF6
HPQWVLTAAHCLKKN	KLK2	56	P20151
SKIFPGNWDNHSHKK	MFGE8	341	Q08431
KNHVHIANPDFIWKS	PARP4	66	Q9UKK3
FHLYWPNKKKDKTHN	RELN	3091	P78509
NPLFHAFVQWCEKHK	PLEKHG6	281	Q3KR16
KAYHKVALKWHPDKN	DNAJB7	21	Q7Z6W7
PAFFQAHMAHKKSLW	HYDIN	836	Q4G0P3
ESHLNKFFWLHKPAK	A3GALT2	291	U3KPV4
IAWKKLLPSQNGFHH	CD244	51	Q9BZW8
HFTAAVPAGHNKWSK	TACO1	51	Q9BSH4
PHDSHSFQAKGIWKK	SMARCAL1	86	Q9NZC9
QVHNGTKYKKFPHWL	STEAP1B	121	Q6NZ63
FFLPWLHNNHTINKK	AQP11	256	Q8NBQ7
NIENHHLHLFKKWKP	ASCC3	1966	Q8N3C0
ALWKGTHHAFQPSKL	USP19	556	O94966
WKVFKKPSHLHQHQI	ZNF865	356	P0CJ78
SPHNHAKLQQLWLKA	SIX2	76	Q9NPC8
VNHFWKLHASKPKNA	UBR4	2626	Q5T4S7
HNPTHLSNKMWKNHI	TNRC6B	1576	Q9UPQ9
PYAHKNWKRKNTHDG	PP2D1	326	A8MPX8
AAAHSQPFAWKKKAL	GEMIN4	56	P57678