Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhigh voltage-gated calcium channel activity

CACNA1A CACNA1H CACNA1G

1.48e-0614333GO:0008331
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

NR4A3 POU4F2 OTX1 ONECUT1 YY1 MAFA ZIC3 MEOX2

2.72e-06560338GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

NR4A3 POU4F2 OTX1 ONECUT1 YY1 MAFA ZIC3 MEOX2

2.95e-06566338GO:0001216
GeneOntologyMolecularFunctionlow voltage-gated calcium channel activity

CACNA1H CACNA1G

7.94e-063332GO:0008332
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

CACNA1A CACNA1H CACNA1G

5.95e-0546333GO:0005245
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

NR4A3 POU4F2 OTX1 ONECUT1 YY1 FOXG1 MAFA ZIC3 MEOX2 FOXB2

6.22e-0514123310GO:0000981
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

NR4A3 POU4F2 OTX1 ONECUT1 YY1 MAFA ZIC3 MEOX2 FOXB2

1.35e-041244339GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

NR4A3 POU4F2 OTX1 ONECUT1 YY1 MAFA ZIC3 MEOX2 FOXB2

1.59e-041271339GO:0000987
GeneOntologyMolecularFunctionSUMO binding

CBX4 RNF111

4.45e-0419332GO:0032183
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

NR4A3 POU4F2 OTX1 ONECUT1 YY1 MAFA ZIC3 MEOX2 FOXB2

4.48e-041459339GO:0000977
GeneOntologyMolecularFunctionscaffold protein binding

DLGAP3 CACNA1H CACNA1G

4.82e-0493333GO:0097110
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

CACNA1H CACNA1G

8.40e-0426332GO:0005248
GeneOntologyMolecularFunctionPDZ domain binding

ERC2 DLGAP3 NKD1

1.09e-03123333GO:0030165
GeneOntologyMolecularFunctionchromatin binding

CCNT1 POU4F2 ARID1B CBX4 ONECUT1 YY1

1.19e-03739336GO:0003682
GeneOntologyMolecularFunctioncalcium channel activity

CACNA1A CACNA1H CACNA1G

1.25e-03129333GO:0005262
GeneOntologyMolecularFunctionmolecular adaptor activity

DYRK1A CCNT1 DLGAP3 ARID1B SORBS2 CBX4 NKD2 ZIC3

1.33e-031356338GO:0060090
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

CACNA1A CACNA1H CACNA1G

1.96e-03151333GO:0015085
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

CACNA1A CACNA1H CACNA1G

2.00e-03152333GO:0022843
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

CACNA1A CACNA1H CACNA1G

3.32e-03182333GO:0005244
GeneOntologyMolecularFunctionsodium channel activity

CACNA1H CACNA1G

3.34e-0352332GO:0005272
GeneOntologyMolecularFunctionvoltage-gated channel activity

CACNA1A CACNA1H CACNA1G

3.43e-03184333GO:0022832
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

CACNA1A SLC39A6 CACNA1H CACNA1G

6.96e-03465334GO:0046873
GeneOntologyBiologicalProcesspattern specification process

OTX1 NKD1 YY1 FOXG1 RNF111 ZIC3 SYNGAP1 MEOX2

1.04e-06526328GO:0007389
GeneOntologyBiologicalProcesssynaptic signaling

CACNA1A ERC2 DLGAP3 CACNA1G ARID1B SORBS2 NCAN IQSEC2 SYNGAP1

1.20e-05976329GO:0099536
GeneOntologyBiologicalProcesssensory organ morphogenesis

NR4A3 OTX1 NKD1 YY1 FOXG1 ZIC3

1.27e-05343326GO:0090596
GeneOntologyBiologicalProcessanterior/posterior pattern specification

OTX1 NKD1 YY1 ZIC3 MEOX2

3.66e-05247325GO:0009952
GeneOntologyBiologicalProcessregulation of calcium ion-dependent exocytosis

CACNA1A CACNA1H CACNA1G

4.60e-0545323GO:0017158
GeneOntologyBiologicalProcessexocytosis

CACNA1A ERC2 NR4A3 CACNA1H CACNA1G NKD2

4.78e-05434326GO:0006887
GeneOntologyBiologicalProcesscalcium ion import across plasma membrane

CACNA1A CACNA1H CACNA1G

5.59e-0548323GO:0098703
GeneOntologyBiologicalProcesscalcium ion import into cytosol

CACNA1A CACNA1H CACNA1G

5.59e-0548323GO:1902656
GeneOntologyBiologicalProcessinorganic ion import across plasma membrane

CACNA1A SLC39A6 CACNA1H CACNA1G

6.67e-05142324GO:0099587
GeneOntologyBiologicalProcesscardiac muscle hypertrophy

DYRK1A NR4A3 SORBS2 YY1

6.67e-05142324GO:0003300
GeneOntologyBiologicalProcessinorganic cation import across plasma membrane

CACNA1A SLC39A6 CACNA1H CACNA1G

6.67e-05142324GO:0098659
GeneOntologyBiologicalProcessanterograde trans-synaptic signaling

CACNA1A ERC2 DLGAP3 CACNA1G ARID1B NCAN IQSEC2 SYNGAP1

6.68e-05931328GO:0098916
GeneOntologyBiologicalProcesschemical synaptic transmission

CACNA1A ERC2 DLGAP3 CACNA1G ARID1B NCAN IQSEC2 SYNGAP1

6.68e-05931328GO:0007268
GeneOntologyBiologicalProcesssynapse organization

CACNA1A ERC2 DLGAP3 SORBS2 NCAN IQSEC2 SYNGAP1

7.04e-05685327GO:0050808
GeneOntologyBiologicalProcesstrans-synaptic signaling

CACNA1A ERC2 DLGAP3 CACNA1G ARID1B NCAN IQSEC2 SYNGAP1

7.10e-05939328GO:0099537
GeneOntologyBiologicalProcessstriated muscle hypertrophy

DYRK1A NR4A3 SORBS2 YY1

7.43e-05146324GO:0014897
GeneOntologyBiologicalProcessmuscle hypertrophy

DYRK1A NR4A3 SORBS2 YY1

7.83e-05148324GO:0014896
GeneOntologyBiologicalProcessregulated exocytosis

CACNA1A ERC2 NR4A3 CACNA1H CACNA1G

7.96e-05291325GO:0045055
GeneOntologyBiologicalProcessregionalization

OTX1 NKD1 YY1 FOXG1 ZIC3 MEOX2

8.15e-05478326GO:0003002
GeneOntologyBiologicalProcesscell growth involved in cardiac muscle cell development

DYRK1A SORBS2 YY1

8.89e-0556323GO:0061049
GeneOntologyBiologicalProcessphysiological cardiac muscle hypertrophy

DYRK1A SORBS2 YY1

8.89e-0556323GO:0003301
GeneOntologyBiologicalProcessphysiological muscle hypertrophy

DYRK1A SORBS2 YY1

8.89e-0556323GO:0003298
GeneOntologyBiologicalProcessear morphogenesis

NR4A3 OTX1 FOXG1 ZIC3

9.13e-05154324GO:0042471
GeneOntologyBiologicalProcesssensory organ development

NR4A3 POU4F2 OTX1 NKD1 YY1 FOXG1 ZIC3

1.05e-04730327GO:0007423
GeneOntologyBiologicalProcesscardiac muscle tissue development

DYRK1A CACNA1G SORBS2 YY1 ZIC3

1.38e-04327325GO:0048738
GeneOntologyBiologicalProcessneuron-neuron synaptic transmission

CACNA1A ARID1B

1.52e-0412322GO:0007270
GeneOntologyBiologicalProcessmuscle system process

DYRK1A NR4A3 CACNA1H CACNA1G SORBS2 YY1

1.70e-04547326GO:0003012
GeneOntologyBiologicalProcessstriated muscle tissue development

DYRK1A CACNA1G SORBS2 YY1 ZIC3

1.86e-04349325GO:0014706
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

CCNT1 NR4A3 POU4F2 OTX1 ONECUT1 YY1 MAFA ZIC3 MEOX2

1.90e-041390329GO:0045944
GeneOntologyBiologicalProcessmuscle tissue development

DYRK1A CACNA1G SORBS2 YY1 ZIC3 MEOX2

1.90e-04558326GO:0060537
GeneOntologyBiologicalProcessneuromuscular process controlling balance

CACNA1A NR4A3 POU4F2

2.04e-0474323GO:0050885
GeneOntologyBiologicalProcesscalcium-ion regulated exocytosis

CACNA1A CACNA1H CACNA1G

2.76e-0482323GO:0017156
GeneOntologyBiologicalProcessmuscle structure development

DYRK1A CACNA1H ARID1B SORBS2 NKD1 YY1 MEOX2

2.84e-04858327GO:0061061
GeneOntologyBiologicalProcessreceptor clustering

CACNA1A SORBS2 SYNGAP1

2.86e-0483323GO:0043113
GeneOntologyBiologicalProcessimport across plasma membrane

CACNA1A SLC39A6 CACNA1H CACNA1G

4.24e-04230324GO:0098739
GeneOntologyBiologicalProcesspositive regulation of calcium ion-dependent exocytosis

CACNA1H CACNA1G

4.35e-0420322GO:0045956
GeneOntologyBiologicalProcesscalcium ion import

CACNA1A CACNA1H CACNA1G

4.67e-0498323GO:0070509
GeneOntologyBiologicalProcessmodulation of chemical synaptic transmission

CACNA1A ERC2 DLGAP3 NCAN IQSEC2 SYNGAP1

4.78e-04663326GO:0050804
GeneOntologyBiologicalProcessregulation of trans-synaptic signaling

CACNA1A ERC2 DLGAP3 NCAN IQSEC2 SYNGAP1

4.82e-04664326GO:0099177
GeneOntologyBiologicalProcesscell junction organization

CACNA1A ERC2 DLGAP3 SORBS2 NCAN IQSEC2 SYNGAP1

6.11e-04974327GO:0034330
GeneOntologyBiologicalProcessatrial cardiac muscle tissue development

CACNA1G ZIC3

6.84e-0425322GO:0003228
GeneOntologyBiologicalProcesstransmission of nerve impulse

CACNA1A CACNA1H CACNA1G

6.89e-04112323GO:0019226
GeneOntologyBiologicalProcessregulation of presynaptic cytosolic calcium ion concentration

CACNA1A ERC2

7.40e-0426322GO:0099509
GeneOntologyBiologicalProcessmembrane depolarization

CACNA1A CACNA1H CACNA1G

8.63e-04121323GO:0051899
GeneOntologyBiologicalProcesscardiac muscle cell development

DYRK1A SORBS2 YY1

8.83e-04122323GO:0055013
GeneOntologyBiologicalProcesssegmentation

NKD1 ZIC3 MEOX2

9.05e-04123323GO:0035282
GeneOntologyBiologicalProcessear development

NR4A3 OTX1 FOXG1 ZIC3

9.46e-04285324GO:0043583
GeneOntologyBiologicalProcessheart development

DYRK1A CACNA1G POU4F2 SORBS2 YY1 ZIC3

9.59e-04757326GO:0007507
GeneOntologyBiologicalProcesssecretion by cell

CACNA1A ERC2 NR4A3 CACNA1H CACNA1G NKD2 MAFA

1.03e-031064327GO:0032940
GeneOntologyBiologicalProcessinner ear morphogenesis

NR4A3 OTX1 FOXG1

1.04e-03129323GO:0042472
GeneOntologyBiologicalProcessreflex

CACNA1A NR4A3

1.05e-0331322GO:0060004
GeneOntologyBiologicalProcesscardiac cell development

DYRK1A SORBS2 YY1

1.11e-03132323GO:0055006
GeneOntologyBiologicalProcessdevelopmental cell growth

DYRK1A POU4F2 SORBS2 YY1

1.16e-03301324GO:0048588
GeneOntologyBiologicalProcesscardiac muscle tissue growth

DYRK1A SORBS2 YY1

1.26e-03138323GO:0055017
GeneOntologyBiologicalProcessneuromuscular synaptic transmission

CACNA1A ERC2

1.42e-0336322GO:0007274
GeneOntologyBiologicalProcessmembrane depolarization during action potential

CACNA1H CACNA1G

1.42e-0336322GO:0086010
GeneOntologyBiologicalProcessheart growth

DYRK1A SORBS2 YY1

1.54e-03148323GO:0060419
GeneOntologyBiologicalProcessregulation of cell growth involved in cardiac muscle cell development

DYRK1A YY1

1.58e-0338322GO:0061050
GeneOntologyBiologicalProcessexport from cell

CACNA1A ERC2 NR4A3 CACNA1H CACNA1G NKD2 MAFA

1.64e-031153327GO:0140352
GeneOntologyBiologicalProcessaxonogenesis

CACNA1A NR4A3 POU4F2 FOXG1 SYNGAP1

1.67e-03566325GO:0007409
GeneOntologyBiologicalProcessmaintenance of synapse structure

ERC2 SYNGAP1

1.75e-0340322GO:0099558
GeneOntologyBiologicalProcessembryonic organ morphogenesis

NR4A3 OTX1 FOXG1 ZIC3

2.03e-03351324GO:0048562
GeneOntologyBiologicalProcessregulation of regulated secretory pathway

CACNA1A CACNA1H CACNA1G

2.10e-03165323GO:1903305
GeneOntologyBiologicalProcesspositive regulation of neuroblast proliferation

FOXG1 NCAN

2.12e-0344322GO:0002052
GeneOntologyBiologicalProcesssecretion

CACNA1A ERC2 NR4A3 CACNA1H CACNA1G NKD2 MAFA

2.28e-031221327GO:0046903
GeneOntologyBiologicalProcesscardiac muscle cell differentiation

DYRK1A SORBS2 YY1

2.57e-03177323GO:0055007
GeneOntologyBiologicalProcessregulation of nervous system development

POU4F2 FOXG1 NCAN IQSEC2 SYNGAP1

2.57e-03625325GO:0051960
GeneOntologyCellularComponentvoltage-gated calcium channel complex

CACNA1A CACNA1H CACNA1G

5.19e-0546333GO:0005891
GeneOntologyCellularComponentchromatin

NR4A3 POU4F2 ARID1B OTX1 ONECUT1 YY1 FOXG1 MAFA MEOX2 FOXB2

6.29e-0514803310GO:0000785
GeneOntologyCellularComponentpresynaptic active zone

CACNA1A ERC2 CACNA1H IQSEC2

6.97e-05141334GO:0048786
GeneOntologyCellularComponentcalcium channel complex

CACNA1A CACNA1H CACNA1G

2.07e-0473333GO:0034704
GeneOntologyCellularComponentglutamatergic synapse

CACNA1A ERC2 DLGAP3 CACNA1H NCAN IQSEC2 SYNGAP1

2.38e-04817337GO:0098978
GeneOntologyCellularComponentdendrite

DYRK1A CACNA1A DLGAP3 CACNA1H CACNA1G SORBS2 SYNGAP1

3.21e-04858337GO:0030425
GeneOntologyCellularComponentvoltage-gated sodium channel complex

CACNA1H CACNA1G

3.24e-0417332GO:0001518
GeneOntologyCellularComponentdendritic tree

DYRK1A CACNA1A DLGAP3 CACNA1H CACNA1G SORBS2 SYNGAP1

3.26e-04860337GO:0097447
GeneOntologyCellularComponentsomatodendritic compartment

DYRK1A CACNA1A ERC2 DLGAP3 CACNA1H CACNA1G SORBS2 SYNGAP1

5.14e-041228338GO:0036477
GeneOntologyCellularComponentnuclear speck

DYRK1A FAM76B POU4F2 CBX4 MEOX2

5.37e-04431335GO:0016607
GeneOntologyCellularComponentpresynaptic active zone cytoplasmic component

ERC2 IQSEC2

5.99e-0423332GO:0098831
GeneOntologyCellularComponentsodium channel complex

CACNA1H CACNA1G

9.55e-0429332GO:0034706
GeneOntologyCellularComponentneuronal cell body

CACNA1A ERC2 DLGAP3 CACNA1H CACNA1G SORBS2

1.75e-03835336GO:0043025
GeneOntologyCellularComponentcell cortex region

ERC2 IQSEC2

2.29e-0345332GO:0099738
GeneOntologyCellularComponentnuclear body

DYRK1A FAM76B POU4F2 CBX4 RNF111 MEOX2

2.60e-03903336GO:0016604
GeneOntologyCellularComponentpostsynaptic density, intracellular component

IQSEC2 SYNGAP1

2.71e-0349332GO:0099092
GeneOntologyCellularComponentcell body

CACNA1A ERC2 DLGAP3 CACNA1H CACNA1G SORBS2

3.00e-03929336GO:0044297
GeneOntologyCellularComponentPcG protein complex

CBX4 YY1

3.05e-0352332GO:0031519
GeneOntologyCellularComponentpostsynaptic specialization, intracellular component

IQSEC2 SYNGAP1

3.53e-0356332GO:0099091
GeneOntologyCellularComponentcation channel complex

CACNA1A CACNA1H CACNA1G

5.97e-03235333GO:0034703
GeneOntologyCellularComponentpresynaptic active zone membrane

CACNA1A CACNA1H

6.73e-0378332GO:0048787
HumanPhenoGaze-evoked horizontal nystagmus

CACNA1A CACNA1G BEAN1

1.32e-0518143HP:0007979
HumanPhenoHyperactivity

DYRK1A CACNA1A CACNA1H ARID1B YY1 FOXG1 IQSEC2 SYNGAP1

3.25e-05558148HP:0000752
HumanPhenoAutism

DYRK1A CACNA1A YY1 FOXG1 IQSEC2 SYNGAP1

3.87e-05264146HP:0000717
HumanPhenoAttention deficit hyperactivity disorder

DYRK1A CACNA1A CACNA1H YY1 FOXG1 IQSEC2 SYNGAP1

4.55e-05413147HP:0007018
HumanPhenoHypertonicity

DYRK1A CACNA1A CACNA1G FOXG1 SYNGAP1

4.85e-05162145HP:0002388
HumanPhenoLimb hypertonia

DYRK1A CACNA1A CACNA1G FOXG1 SYNGAP1

4.85e-05162145HP:0002509
HumanPhenoAtonic seizure

DYRK1A CACNA1A IQSEC2 SYNGAP1

9.45e-0594144HP:0010819
HumanPhenoAbnormality of upper lip vermillion

DYRK1A CACNA1A ARID1B YY1 FOXG1 IQSEC2 SYNGAP1

9.68e-05464147HP:0011339
HumanPhenoInterictal epileptiform activity

CACNA1A CACNA1H CACNA1G FOXG1 IQSEC2 SYNGAP1

1.13e-04319146HP:0011182
HumanPhenoInterictal EEG abnormality

CACNA1A CACNA1H CACNA1G FOXG1 IQSEC2 SYNGAP1

1.25e-04325146HP:0025373
HumanPhenoAbnormal social development

DYRK1A CACNA1A CACNA1H CACNA1G ARID1B YY1 FOXG1 IQSEC2 SYNGAP1

1.48e-04908149HP:0025732
HumanPhenoShort attention span

DYRK1A CACNA1A CACNA1H YY1 FOXG1 IQSEC2 SYNGAP1

1.94e-04517147HP:0000736
HumanPhenoAbnormality of pain sensation

CACNA1A YY1 IQSEC2 SYNGAP1

1.94e-04113144HP:0010832
HumanPhenoAbnormal demeanor

DYRK1A FOXG1 IQSEC2

2.05e-0444143HP:5200261
HumanPhenoHorizontal nystagmus

CACNA1A CACNA1G BEAN1 IQSEC2

2.07e-04115144HP:0000666
HumanPhenoAbnormal tongue physiology

DYRK1A CACNA1A FOXG1 SYNGAP1

2.07e-04115144HP:0030810
HumanPhenoReduced attention regulation

DYRK1A CACNA1A CACNA1H YY1 FOXG1 IQSEC2 SYNGAP1

2.16e-04526147HP:5200044
HumanPhenoEEG with focal epileptiform discharges

CACNA1A CACNA1G IQSEC2 SYNGAP1

2.29e-04118144HP:0011185
HumanPhenoRestricted or repetitive behaviors or interests

DYRK1A CACNA1H ARID1B FOXG1 IQSEC2 SYNGAP1

2.49e-04368146HP:0031432
HumanPhenoSlanting of the palpebral fissure

DYRK1A CACNA1A CACNA1G ARID1B YY1 FOXG1 IQSEC2 SYNGAP1

2.52e-04739148HP:0200006
HumanPhenoIntellectual disability, severe

DYRK1A ARID1B YY1 FOXG1 IQSEC2 SYNGAP1

2.60e-04371146HP:0010864
HumanPhenoPerseverative thought

DYRK1A CACNA1H ARID1B FOXG1 IQSEC2 SYNGAP1

2.84e-04377146HP:0030223
HumanPhenoAbnormal eating behavior

CACNA1A ARID1B YY1 SYNGAP1

3.13e-04128144HP:0100738
HumanPhenoDisordered formal thought process

DYRK1A CACNA1H ARID1B FOXG1 IQSEC2 SYNGAP1

3.24e-04386146HP:0025769
HumanPhenoAbnormal lower lip morphology

DYRK1A ARID1B YY1 FOXG1 SYNGAP1

3.27e-04242145HP:0000178
HumanPhenoEEG with multifocal slow activity

CACNA1A FOXG1 SYNGAP1

3.37e-0452143HP:0010844
HumanPhenoThick lower lip vermilion

DYRK1A ARID1B YY1 SYNGAP1

3.95e-04136144HP:0000179
HumanPhenoGaze-evoked nystagmus

CACNA1A CACNA1G BEAN1

3.99e-0455143HP:0000640
HumanPhenoAbnormal thought pattern

DYRK1A CACNA1H ARID1B FOXG1 IQSEC2 SYNGAP1

4.16e-04404146HP:5200269
HumanPhenoSteroetypic upper-extremity movements

DYRK1A IQSEC2 SYNGAP1

4.43e-0457143HP:5200018
HumanPhenoAbnormality of the chin

DYRK1A CACNA1G ARID1B YY1 FOXG1 IQSEC2

4.44e-04409146HP:0000306
HumanPhenoAbnormal response to social norms

DYRK1A CACNA1A CACNA1H ARID1B YY1 FOXG1 IQSEC2 SYNGAP1

4.71e-04807148HP:5200123
HumanPhenoSocial disinhibition

DYRK1A CACNA1A CACNA1H ARID1B YY1 FOXG1 IQSEC2 SYNGAP1

4.71e-04807148HP:5200029
HumanPhenoDisinhibition

DYRK1A CACNA1A CACNA1H ARID1B YY1 FOXG1 IQSEC2 SYNGAP1

4.71e-04807148HP:0000734
HumanPhenoInappropriate behavior

DYRK1A CACNA1A CACNA1H ARID1B YY1 FOXG1 IQSEC2 SYNGAP1

4.71e-04807148HP:0000719
HumanPhenoInfection-related seizure

DYRK1A CACNA1A CACNA1H SYNGAP1

5.05e-04145144HP:0032892
HumanPhenoSeizure precipitated by febrile infection

DYRK1A CACNA1A CACNA1H SYNGAP1

5.05e-04145144HP:0032894
HumanPhenoFebrile seizure (within the age range of 3 months to 6 years)

DYRK1A CACNA1A CACNA1H SYNGAP1

5.05e-04145144HP:0002373
HumanPhenoImpulsivity

CACNA1A FOXG1 IQSEC2 SYNGAP1

5.60e-04149144HP:0100710
HumanPhenoMyoclonic absence seizure

CACNA1H SYNGAP1

6.26e-0414142HP:0011150
HumanPhenoAnteverted ears

CACNA1G SYNGAP1

6.26e-0414142HP:0040080
HumanPhenoAbsent speech

DYRK1A ARID1B YY1 FOXG1 IQSEC2 SYNGAP1

6.29e-04436146HP:0001344
HumanPhenoMotor stereotypy

DYRK1A CACNA1H FOXG1 IQSEC2 SYNGAP1

6.43e-04280145HP:0000733
HumanPhenoSomatic sensory dysfunction

CACNA1A CACNA1G YY1 BEAN1 IQSEC2 SYNGAP1

6.53e-04439146HP:0003474
HumanPhenoProminent lips

DYRK1A ARID1B YY1 SYNGAP1

6.66e-04156144HP:0000184
HumanPhenoAbnormally increased volition

DYRK1A CACNA1A CACNA1H ARID1B YY1 FOXG1 IQSEC2 SYNGAP1

7.93e-04869148HP:5200263
HumanPhenoEEG with focal spike waves

IQSEC2 SYNGAP1

8.23e-0416142HP:0011197
HumanPhenoAbsence seizures with special features

CACNA1H SYNGAP1

8.23e-0416142HP:0011148
HumanPhenoAbnormal relationship

IQSEC2 SYNGAP1

8.23e-0416142HP:5200024
HumanPhenoBrain imaging abnormality

DYRK1A CACNA1A CACNA1G SYNGAP1

8.62e-04167144HP:0410263
HumanPhenoAbnormality of the palpebral fissures

DYRK1A CACNA1A CACNA1G ARID1B YY1 FOXG1 IQSEC2 SYNGAP1

8.65e-04880148HP:0008050
HumanPhenoDeficiency of speech development

DYRK1A ARID1B YY1 FOXG1 IQSEC2 SYNGAP1

8.69e-04463146HP:0002116
HumanPhenoImpairment in personality functioning

DYRK1A CACNA1A CACNA1H CACNA1G ARID1B YY1 FOXG1 IQSEC2 SYNGAP1

9.12e-041141149HP:0031466
HumanPhenoTongue thrusting

DYRK1A FOXG1

9.32e-0417142HP:0100703
HumanPhenoInappropriate crying

FOXG1 IQSEC2

1.05e-0318142HP:0030215
HumanPhenoGeneralized non-motor (absence) seizure

DYRK1A CACNA1A CACNA1H SYNGAP1

1.05e-03176144HP:0002121
HumanPhenoAutistic behavior

DYRK1A CACNA1A ARID1B YY1 FOXG1 IQSEC2 SYNGAP1

1.05e-03678147HP:0000729
HumanPhenoDownslanted palpebral fissures

DYRK1A CACNA1A ARID1B YY1 FOXG1 SYNGAP1

1.27e-03497146HP:0000494
HumanPhenoShort nose

DYRK1A CACNA1G ARID1B FOXG1 IQSEC2

1.27e-03325145HP:0003196
HumanPhenoAbnormal rapid eye movement sleep

YY1 IQSEC2

1.30e-0320142HP:0002494
HumanPhenoSensory neuropathy

CACNA1A CACNA1G YY1 BEAN1 IQSEC2 SYNGAP1

1.35e-03503146HP:0000763
HumanPhenoAggressive behavior

DYRK1A CACNA1A ARID1B FOXG1 IQSEC2 SYNGAP1

1.55e-03516146HP:0000718
HumanPhenoAbnormal aggressive, impulsive or violent behavior

DYRK1A CACNA1A ARID1B FOXG1 IQSEC2 SYNGAP1

1.55e-03516146HP:0006919
HumanPhenoAbnormal duodenum morphology

DYRK1A ARID1B ZIC3

1.58e-0388143HP:0002246
HumanPhenoEEG with abnormally slow frequencies

CACNA1A FOXG1 SYNGAP1

1.58e-0388143HP:0011203
HumanPhenoNon-motor seizure

DYRK1A CACNA1A CACNA1H SYNGAP1

1.60e-03197144HP:0033259
HumanPhenoAbnormality of central nervous system electrophysiology

CACNA1A CACNA1H CACNA1G ARID1B FOXG1 IQSEC2 SYNGAP1

1.76e-03738147HP:0030178
HumanPhenoInvoluntary movements

DYRK1A CACNA1A CACNA1H CACNA1G YY1 BEAN1 FOXG1 IQSEC2 SYNGAP1

1.82e-031248149HP:0004305
HumanPhenoAbnormal stomach morphology

DYRK1A CACNA1A ARID1B FOXG1 IQSEC2 ZIC3 SYNGAP1

1.82e-03742147HP:0002577
HumanPhenoGastrointestinal atresia

DYRK1A YY1 ZIC3

1.85e-0393143HP:0002589
HumanPhenoDiagnostic behavioral phenotype

DYRK1A CACNA1A ARID1B YY1 FOXG1 IQSEC2 SYNGAP1

1.90e-03747147HP:0025783
HumanPhenoUnsteady gait

CACNA1A CACNA1G ARID1B FOXG1 SYNGAP1

1.94e-03357145HP:0002317
HumanPhenoAbnormal volitional state

DYRK1A CACNA1A CACNA1H CACNA1G ARID1B YY1 FOXG1 IQSEC2 SYNGAP1

1.99e-031263149HP:0025780
HumanPhenoAbnormal motivation

DYRK1A CACNA1A CACNA1H CACNA1G ARID1B YY1 FOXG1 IQSEC2 SYNGAP1

1.99e-031263149HP:5200275
HumanPhenoEEG abnormality

CACNA1A CACNA1H CACNA1G FOXG1 IQSEC2 SYNGAP1

2.12e-03548146HP:0002353
HumanPhenoSaccadic smooth pursuit

CACNA1A CACNA1G

2.20e-0326142HP:0001152
HumanPhenoSimple febrile seizure

DYRK1A SYNGAP1

2.37e-0327142HP:0011171
HumanPhenoHyperinsulinemic hypoglycemia

YY1 MAFA

2.37e-0327142HP:0000825
HumanPhenoAbnormality of the pancreatic islet cells

YY1 MAFA

2.55e-0328142HP:0006476
HumanPhenoReduced impulse control

DYRK1A CACNA1A CACNA1H ARID1B YY1 FOXG1 IQSEC2 SYNGAP1

2.58e-031032148HP:5200045
HumanPhenoStereotypical hand wringing

DYRK1A IQSEC2

2.73e-0329142HP:0012171
HumanPhenoMidline hand movements

DYRK1A IQSEC2

2.73e-0329142HP:5200009
HumanPhenoSacral dimple

DYRK1A ARID1B ZIC3

3.00e-03110143HP:0000960
HumanPhenoBilateral tonic-clonic seizure

DYRK1A CACNA1A CACNA1H IQSEC2 SYNGAP1

3.01e-03394145HP:0002069
HumanPhenoDecreased fetal movement

CACNA1A FOXG1 IQSEC2 SYNGAP1

3.02e-03234144HP:0001558
HumanPhenoPoor head control

CACNA1A CACNA1G FOXG1 SYNGAP1

3.06e-03235144HP:0002421
HumanPhenoAbnormality of endocrine pancreas physiology

YY1 MAFA

3.12e-0331142HP:0012093
MousePhenoabnormal hippocampus morphology

DYRK1A NR4A3 ARID1B OTX1 FOXG1 IQSEC2 ZIC3 SYNGAP1

2.53e-07331298MP:0000807
MousePhenoabnormal temporal lobe morphology

DYRK1A NR4A3 ARID1B OTX1 FOXG1 IQSEC2 ZIC3 SYNGAP1

2.90e-07337298MP:0000801
MousePhenoabnormal limbic system morphology

DYRK1A NR4A3 ARID1B OTX1 FOXG1 IQSEC2 ZIC3 SYNGAP1

6.93e-07378298MP:0004166
MousePhenoabnormal seizure response to inducing agent

DYRK1A CACNA1A NR4A3 CACNA1G IQSEC2 SYNGAP1

2.96e-06201296MP:0009357
MousePhenoabnormal hippocampus size

DYRK1A OTX1 FOXG1 IQSEC2

4.73e-0655294MP:0008281
MousePhenoseizures

DYRK1A CACNA1A NR4A3 CACNA1G OTX1 IQSEC2 SYNGAP1

6.78e-06360297MP:0002064
MousePhenoabnormal superior colliculus morphology

DYRK1A POU4F2 OTX1

1.04e-0521293MP:0000904
MousePhenoabnormal seizure response to pharmacological agent

CACNA1A NR4A3 CACNA1G IQSEC2 SYNGAP1

1.16e-05147295MP:0000950
MousePhenoconvulsive seizures

CACNA1A NR4A3 OTX1 IQSEC2 SYNGAP1

1.41e-05153295MP:0000947
MousePhenoabnormal cerebral hemisphere morphology

DYRK1A NR4A3 ARID1B OTX1 FOXG1 IQSEC2 ZIC3 SYNGAP1

2.09e-05599298MP:0008540
MousePhenoabnormal telencephalon morphology

DYRK1A NR4A3 DLGAP3 ARID1B OTX1 FOXG1 IQSEC2 ZIC3 SYNGAP1

2.51e-05812299MP:0000787
MousePhenoabnormal behavioral response to xenobiotic

CACNA1A NR4A3 DLGAP3 CACNA1G IQSEC2 SYNGAP1

3.44e-05309296MP:0009745
MousePhenoabnormal synaptic transmission

CACNA1A ERC2 DLGAP3 CACNA1H CACNA1G ARID1B SORBS2 NCAN IQSEC2 SYNGAP1

3.45e-0510702910MP:0003635
MousePhenoabnormal synaptic physiology

CACNA1A ERC2 DLGAP3 CACNA1H CACNA1G ARID1B SORBS2 NCAN IQSEC2 SYNGAP1

3.62e-0510762910MP:0021009
MousePhenoabnormal channel response

CACNA1A CACNA1H CACNA1G

4.20e-0533293MP:0003484
MousePhenoabnormal tectum morphology

DYRK1A POU4F2 OTX1

5.02e-0535293MP:0006104
MousePhenoabnormal midbrain roof plate morphology

DYRK1A POU4F2 OTX1

5.02e-0535293MP:0006103
MousePhenoabnormal corpora quadrigemina morphology

DYRK1A POU4F2 OTX1

5.02e-0535293MP:0000899
MousePhenodecreased superior colliculus size

DYRK1A OTX1

6.20e-056292MP:0002892
MousePhenodecreased social investigation

DYRK1A IQSEC2 SYNGAP1

6.45e-0538293MP:0021111
MousePhenostereotypic behavior

CACNA1A NR4A3 ARID1B OTX1 SYNGAP1

7.06e-05214295MP:0001408
MousePhenononconvulsive seizures

CACNA1A CACNA1G OTX1

7.53e-0540293MP:0000948
MousePhenoabnormal miniature excitatory postsynaptic currents

CACNA1A SORBS2 IQSEC2 SYNGAP1

9.11e-05116294MP:0004753
MousePhenoabnormal brainstem morphology

DYRK1A CACNA1A POU4F2 OTX1 ZIC3

9.33e-05227295MP:0005277
MousePhenosmall hippocampus

DYRK1A OTX1 FOXG1

1.15e-0446293MP:0008283
MousePhenocognitive inflexibility

DYRK1A ARID1B

1.15e-048292MP:0014115
MousePhenoabnormal nervous system development

DYRK1A CACNA1A NR4A3 ARID1B OTX1 YY1 FOXG1 IQSEC2 RNF111 ZIC3

1.36e-0412572910MP:0003861
MousePhenoabnormal thalamus morphology

DYRK1A FOXG1 ZIC3

1.85e-0454293MP:0000832
MousePhenoabnormal forebrain morphology

DYRK1A NR4A3 DLGAP3 ARID1B OTX1 FOXG1 IQSEC2 ZIC3 SYNGAP1

2.18e-041072299MP:0000783
MousePhenodecreased hippocampus volume

DYRK1A FOXG1

2.26e-0411292MP:0020083
MousePhenoabnormal midbrain morphology

DYRK1A POU4F2 OTX1 ZIC3

2.52e-04151294MP:0000897
MousePhenoabnormal brain development

CACNA1A NR4A3 ARID1B OTX1 FOXG1 RNF111 ZIC3

2.58e-04638297MP:0000913
MousePhenopostnatal growth retardation

ARID1B OTX1 NKD1 ONECUT1 IQSEC2 MAFA ZIC3 SYNGAP1

3.15e-04881298MP:0001732
MousePhenoabnormal postnatal growth

ARID1B OTX1 NKD1 ONECUT1 IQSEC2 MAFA ZIC3 SYNGAP1

3.84e-04907298MP:0001731
MousePhenoabnormal social investigation

DYRK1A ARID1B IQSEC2 SYNGAP1

4.04e-04171294MP:0001360
MousePhenoabnormal hippocampus pyramidal cell layer

NR4A3 ARID1B SYNGAP1

4.17e-0471293MP:0008284
MousePhenoabnormal cerebral cortex morphology

DYRK1A ARID1B OTX1 FOXG1 ZIC3

5.15e-04328295MP:0000788
MousePhenoabnormal CNS synaptic transmission

CACNA1A ERC2 DLGAP3 ARID1B SORBS2 NCAN IQSEC2 SYNGAP1

6.68e-04985298MP:0002206
MousePhenoretina ganglion cell degeneration

POU4F2 PRICKLE3

6.95e-0419292MP:0008067
MousePhenoabnormal dentate gyrus morphology

DYRK1A ARID1B IQSEC2

7.32e-0486293MP:0000812
MousePhenosocial withdrawal

IQSEC2 SYNGAP1

8.52e-0421292MP:0001361
MousePhenoabnormal hippocampus layer morphology

NR4A3 ARID1B SYNGAP1

8.90e-0492293MP:0000813
MousePhenodecreased midbrain size

DYRK1A OTX1

1.02e-0323292MP:0012089
MousePhenoabnormal spike wave discharge

CACNA1A CACNA1G

1.11e-0324292MP:0008840
MousePhenoabnormal PQ interval

CACNA1G SORBS2

1.11e-0324292MP:0011918
MousePhenoabnormal eye electrophysiology

ERC2 POU4F2 PRICKLE3 FOXG1

1.19e-03228294MP:0005551
MousePhenoabnormal excitatory postsynaptic potential

CACNA1A DLGAP3 SYNGAP1

1.20e-03102293MP:0002912
MousePhenopostnatal lethality

DYRK1A CACNA1A OTX1 SORBS2 ONECUT1 ZIC3 SYNGAP1 MEOX2

1.25e-031084298MP:0002082
MousePhenoabnormal neuron physiology

NR4A3 CACNA1G POU4F2 FOXG1 IQSEC2 SYNGAP1

1.29e-03604296MP:0004811
MousePhenoabnormal basal ganglion morphology

DLGAP3 FOXG1 ZIC3

1.34e-03106293MP:0006007
MousePhenoabnormal vocalization

DYRK1A CACNA1H ARID1B IQSEC2

1.37e-03237294MP:0001529
MousePhenoabnormal dendrite morphology

CACNA1A SORBS2 PRICKLE3 SYNGAP1

1.37e-03237294MP:0008143
MousePhenosporadic seizures

CACNA1A IQSEC2

1.41e-0327292MP:0000951
MousePhenoabnormal social/conspecific interaction behavior

DYRK1A CACNA1A ARID1B IQSEC2 SYNGAP1

1.58e-03421295MP:0002557
MousePhenolethality during fetal growth through weaning, incomplete penetrance

DYRK1A CACNA1A OTX1 SORBS2 ONECUT1 YY1 ZIC3 MEOX2

1.59e-031124298MP:0011112
MousePhenodecreased susceptibility to induction of seizure by inducing agent

CACNA1G IQSEC2

1.63e-0329292MP:0012348
MousePhenodecreased susceptibility to pharmacologically induced seizures

CACNA1G IQSEC2

1.63e-0329292MP:0002887
MousePhenothin cerebellar molecular layer

CACNA1A CACNA1G

1.74e-0330292MP:0000890
MousePhenocircling

CACNA1A NR4A3 OTX1

1.78e-03117293MP:0001394
MousePhenoincreased susceptibility to pharmacologically induced seizures

CACNA1A NR4A3 SYNGAP1

1.78e-03117293MP:0002906
MousePhenoincreased susceptibility to induction of seizure by inducing agent

CACNA1A NR4A3 SYNGAP1

1.83e-03118293MP:0012349
MousePhenoabnormal exploration in a new environment

CCNT1 ERC2 CACNA1G ARID1B SORBS2 IQSEC2

1.83e-03647296MP:0013189
MousePhenoabnormal midbrain size

DYRK1A OTX1

1.86e-0331292MP:0012088
MousePhenoabnormal cerebral cortex pyramidal cell morphology

DYRK1A FOXG1

1.98e-0332292MP:0009969
MousePhenopostnatal lethality, incomplete penetrance

DYRK1A OTX1 SORBS2 ONECUT1 ZIC3 MEOX2

2.17e-03669296MP:0011086
MousePhenoabnormal neuron number

CACNA1A NR4A3 POU4F2 ARID1B FOXG1

2.24e-03456295MP:0008946
MousePhenoabsence seizures

CACNA1A CACNA1G

2.37e-0335292MP:0003216
MousePhenoabnormal response to new environment

CCNT1 ERC2 CACNA1G ARID1B SORBS2 IQSEC2

2.48e-03687296MP:0001413
MousePhenoabnormal hindbrain morphology

DYRK1A CACNA1A CACNA1G OTX1 ZIC3

2.93e-03485295MP:0000841
MousePhenoabnormal learning/memory/conditioning

DYRK1A CCNT1 ERC2 CACNA1G ARID1B SORBS2 IQSEC2 SYNGAP1

2.95e-031239298MP:0002063
MousePhenodecreased brain size

DYRK1A OTX1 FOXG1 SYNGAP1

3.04e-03295294MP:0000774
MousePhenoabnormal cognition

DYRK1A CCNT1 ERC2 CACNA1G ARID1B SORBS2 IQSEC2 SYNGAP1

3.05e-031246298MP:0014114
MousePhenoabnormal diencephalon morphology

DYRK1A OTX1 FOXG1 ZIC3

3.16e-03298294MP:0000830
MousePhenoabnormal cerebellar cortex morphology

CACNA1A CACNA1G OTX1 ZIC3

3.23e-03300294MP:0004097
MousePhenoabnormal long-term spatial reference memory

DYRK1A ARID1B

3.24e-0341292MP:0008432
MousePhenoincreased exploration in new environment

ERC2 CACNA1G IQSEC2

3.61e-03150293MP:0001415
MousePhenoabnormal reflex

CACNA1A CCNT1 POU4F2 ARID1B SORBS2 ZIC3 SYNGAP1 MEOX2

3.86e-031294298MP:0001961
MousePhenoenvironmentally induced seizures

DYRK1A SYNGAP1

3.89e-0345292MP:0009358
MousePhenodecreased vocalization

DYRK1A IQSEC2

4.06e-0346292MP:0020351
DomainVDCCAlpha1

CACNA1A CACNA1H CACNA1G

5.44e-0710323IPR002077
DomainVDCC_T_a1

CACNA1H CACNA1G

8.52e-063322IPR005445
DomainChannel_four-helix_dom

CACNA1A CACNA1H CACNA1G

1.26e-0457323IPR027359
Domain-

CACNA1A CACNA1H CACNA1G

1.26e-04573231.20.120.350
DomainHomeobox

POU4F2 OTX1 ONECUT1 MEOX2

6.56e-04234324PF00046
DomainHOMEOBOX_1

POU4F2 OTX1 ONECUT1 MEOX2

6.77e-04236324PS00027
DomainHOX

POU4F2 OTX1 ONECUT1 MEOX2

6.88e-04237324SM00389
DomainHomeobox_dom

POU4F2 OTX1 ONECUT1 MEOX2

7.10e-04239324IPR001356
DomainHOMEOBOX_2

POU4F2 OTX1 ONECUT1 MEOX2

7.10e-04239324PS50071
DomainIon_trans_dom

CACNA1A CACNA1H CACNA1G

9.66e-04114323IPR005821
DomainIon_trans

CACNA1A CACNA1H CACNA1G

9.66e-04114323PF00520
Domain-

POU4F2 ONECUT1

9.72e-04273221.10.260.40
DomainLambda_DNA-bd_dom

POU4F2 ONECUT1

1.12e-0329322IPR010982
Domain-

POU4F2 OTX1 ONECUT1 MEOX2

1.33e-032833241.10.10.60
DomainHomeodomain-like

POU4F2 OTX1 ONECUT1 MEOX2

2.38e-03332324IPR009057
DomainTF_fork_head_CS_2

FOXG1 FOXB2

2.81e-0346322IPR030456
DomainTF_fork_head_CS_1

FOXG1 FOXB2

2.93e-0347322IPR018122
DomainFORK_HEAD_3

FOXG1 FOXB2

3.18e-0349322PS50039
DomainFH

FOXG1 FOXB2

3.18e-0349322SM00339
DomainFORK_HEAD_1

FOXG1 FOXB2

3.18e-0349322PS00657
DomainFORK_HEAD_2

FOXG1 FOXB2

3.18e-0349322PS00658
DomainForkhead

FOXG1 FOXB2

3.18e-0349322PF00250
DomainFork_head_dom

FOXG1 FOXB2

3.18e-0349322IPR001766
DomainHomeobox_CS

POU4F2 OTX1 MEOX2

3.90e-03186323IPR017970
PathwayKEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY

CACNA1A CACNA1H CACNA1G

8.52e-0623253M47666
PathwayKEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL

CACNA1A CACNA1H CACNA1G

1.10e-0525253M47948
PathwayREACTOME_NCAM1_INTERACTIONS

CACNA1H CACNA1G NCAN

5.40e-0542253M7169
PathwayKEGG_TYPE_II_DIABETES_MELLITUS

CACNA1A CACNA1G MAFA

7.59e-0547253M19708
PathwayBIOCARTA_PRC2_PATHWAY

CBX4 YY1

1.64e-0411252MM1548
PathwayREACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH

CACNA1H CACNA1G NCAN

1.82e-0463253M11187
PathwayBIOCARTA_PRC2_PATHWAY

CBX4 YY1

2.71e-0414252M22025
PathwayWP_TYPE_II_DIABETES_MELLITUS

CACNA1A MAFA

6.82e-0422252M39658
PathwayKEGG_MATURITY_ONSET_DIABETES_OF_THE_YOUNG

ONECUT1 MAFA

8.83e-0425252M18312
PathwayKEGG_MEDICUS_REFERENCE_DEUBIQUITINATION_OF_H2AK119

CBX4 YY1

9.56e-0426252M47923
PathwayREACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION

CCNT1 RNF111

9.56e-0426252MM14878
PathwayREACTOME_NEUREXINS_AND_NEUROLIGINS

DLGAP3 SORBS2

1.45e-0332252MM15326
PathwayREACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION

CCNT1 RNF111

1.83e-0336252M633
PathwayREACTOME_GENERIC_TRANSCRIPTION_PATHWAY

CCNT1 NR4A3 POU4F2 CBX4 FOXG1 RNF111

1.86e-03768256MM14851
PathwayREACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN

ARID1B CBX4

1.94e-0337252M27797
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

CCNT1 NR4A3 POU4F2 ARID1B CBX4 YY1 FOXG1 RNF111

2.02e-031387258M734
PathwayREACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER

CCNT1 RNF111

2.37e-0341252MM14876
PathwayREACTOME_DEVELOPMENTAL_BIOLOGY

CACNA1H CACNA1G ARID1B ONECUT1 YY1 NCAN MAFA ZIC3

2.47e-031432258M509
PathwayREACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT

ONECUT1 MAFA

2.49e-0342252M17541
PathwayREACTOME_SMOOTH_MUSCLE_CONTRACTION

CACNA1H CACNA1G

2.61e-0343252M1429
PathwayWP_RETT_SYNDROME

FOXG1 SYNGAP1

3.24e-0348252M39759
PathwayREACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER

CCNT1 RNF111

3.65e-0351252M665
PathwayKEGG_CALCIUM_SIGNALING_PATHWAY

CACNA1A CACNA1H CACNA1G

3.71e-03178253M2890
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

DYRK1A FAM76B SLC39A6 USP34 CCNT1 ERC2 NR4A3 DLGAP3 ARID1B OTX1 CBX4 NKD1 NKD2 PRICKLE3 ONECUT1 YY1 FOXG1 IQSEC2 MAFA RNF111 ZIC3 SYNGAP1

8.03e-251203332229180619
Pubmed

The PcG protein hPc2 interacts with the N-terminus of histone demethylase JARID1B and acts as a transcriptional co-repressor.

CACNA1A SLC39A6 NR4A3 CACNA1H ARID1B CBX4 MEOX2

1.47e-153333719336002
Pubmed

Adult loss of Cacna1a in mice recapitulates childhood absence epilepsy by distinct thalamic bursting mechanisms.

CACNA1A CACNA1H CACNA1G

3.11e-09433331800012
Pubmed

Functional importance of L- and P/Q-type voltage-gated calcium channels in human renal vasculature.

CACNA1A CACNA1H CACNA1G

3.11e-09433321788606
Pubmed

International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.

CACNA1A CACNA1H CACNA1G

6.51e-08933316382099
Pubmed

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

ERC2 DLGAP3 SORBS2 NCAN IQSEC2 SYNGAP1

1.25e-0725133627507650
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

DYRK1A CACNA1A ERC2 DLGAP3 SORBS2 FOXG1 NCAN IQSEC2 SYNGAP1

1.96e-0796333928671696
Pubmed

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

OTX1 ONECUT1 YY1 FOXG1 MAFA ZIC3 MEOX2

6.62e-0754433728473536
Pubmed

Chronic deficit in nitric oxide elicits oxidative stress and augments T-type calcium-channel contribution to vascular tone of rodent arteries and arterioles.

CACNA1H CACNA1G

8.73e-07233223436820
Pubmed

Cav3.2 subunit underlies the functional T-type Ca2+ channel in murine hearts during the embryonic period.

CACNA1H CACNA1G

8.73e-07233214988077
Pubmed

Different distribution of Cav3.2 and Cav3.1 transcripts encoding T-type Ca(2+) channels in the embryonic heart of mice.

CACNA1H CACNA1G

8.73e-07233221079360
Pubmed

Viable mice with compound mutations in the Wnt/Dvl pathway antagonists nkd1 and nkd2.

NKD1 NKD2

8.73e-07233217438140
Pubmed

Molecular cloning, gene structure, and expression analyses of NKD1 and NKD2.

NKD1 NKD2

8.73e-07233211604995
Pubmed

Role of T-type calcium channel subunits in post-myocardial infarction remodelling probed with genetically engineered mice.

CACNA1H CACNA1G

8.73e-07233221622683
Pubmed

Deficiency of T-type Ca2+ channels Cav3.1 and Cav3.2 has no effect on angiotensin II-induced hypertension but differential effect on plasma aldosterone in mice.

CACNA1H CACNA1G

8.73e-07233231042060
Pubmed

Vertebrate proteins related to Drosophila Naked Cuticle bind Dishevelled and antagonize Wnt signaling.

NKD1 NKD2

8.73e-07233211356022
Pubmed

Subthreshold membrane potential oscillations in inferior olive neurons are dynamically regulated by P/Q- and T-type calcium channels: a study in mutant mice.

CACNA1A CACNA1G

8.73e-07233220547676
Pubmed

The Ca(v)3.1 T-type calcium channel is required for neointimal formation in response to vascular injury in mice.

CACNA1H CACNA1G

8.73e-07233222886848
Pubmed

Ca(v)3.2 T-type Ca2+ channel-dependent activation of ERK in paraventricular thalamus modulates acid-induced chronic muscle pain.

CACNA1H CACNA1G

8.73e-07233220685979
Pubmed

Deletion of T-type calcium channels Cav3.1 or Cav3.2 attenuates endothelial dysfunction in aging mice.

CACNA1H CACNA1G

8.73e-07233229082441
Pubmed

[Decreased mRNA expressions of T-type channel alpha1H and alpha1G in the sperm of varicocele patients and their implication].

CACNA1H CACNA1G

8.73e-07233222574369
Pubmed

Blockade of T-type Ca(2+) channels inhibits human ovarian cancer cell proliferation.

CACNA1H CACNA1G

8.73e-07233221438841
Pubmed

T-type voltage-activated calcium channel Cav3.1, but not Cav3.2, is involved in the inhibition of proliferation and apoptosis in MCF-7 human breast cancer cells.

CACNA1H CACNA1G

8.73e-07233222469755
Pubmed

β-Adrenergic stimulation increases Cav3.1 activity in cardiac myocytes through protein kinase A.

CACNA1H CACNA1G

8.73e-07233222808078
Pubmed

A census of human transcription factors: function, expression and evolution.

NR4A3 POU4F2 OTX1 ONECUT1 YY1 FOXG1 MAFA MEOX2

1.63e-0690833819274049
Pubmed

5,6-EET potently inhibits T-type calcium channels: implication in the regulation of the vascular tone.

CACNA1H CACNA1G

2.62e-06333224327205
Pubmed

Ethanol inhibition of a T-type Ca²+ channel through activity of protein kinase C.

CACNA1H CACNA1G

2.62e-06333223488970
Pubmed

Differential effect of T-type voltage-gated Ca2+ channel disruption on renal plasma flow and glomerular filtration rate in vivo.

CACNA1H CACNA1G

2.62e-06333224966091
Pubmed

PR72, a novel regulator of Wnt signaling required for Naked cuticle function.

NKD1 NKD2

2.62e-06333215687260
Pubmed

T-type channels: release a brake, engage a gear.

CACNA1H CACNA1G

2.62e-06333226488564
Pubmed

Association study between polymorphisms in the CACNA1A, CACNA1C, and CACNA1H genes and drug-resistant epilepsy in the Chinese Han population.

CACNA1A CACNA1H

2.62e-06333226216687
Pubmed

T-type, but not L-type, voltage-gated calcium channels are dispensable for lymphatic pacemaking and spontaneous contractions.

CACNA1H CACNA1G

2.62e-06333231919478
Pubmed

Eps15 Homology Domain-containing Protein 3 Regulates Cardiac T-type Ca2+ Channel Targeting and Function in the Atria.

CACNA1H CACNA1G

2.62e-06333225825486
Pubmed

Differential interactions of Na+ channel toxins with T-type Ca2+ channels.

CACNA1H CACNA1G

2.62e-06333218591418
Pubmed

Identification of the t-type calcium channel (Ca(v)3.1d) in developing mouse heart.

CACNA1H CACNA1G

2.62e-06333211230107
Pubmed

Alpha(1H) mRNA in single skeletal muscle fibres accounts for T-type calcium current transient expression during fetal development in mice.

CACNA1H CACNA1G

2.62e-06333211897840
Pubmed

Prognostic relevance of a T-type calcium channels gene signature in solid tumours: A correlation ready for clinical validation.

CACNA1H CACNA1G

2.62e-06333228846697
Pubmed

Caveolin-3 regulates protein kinase A modulation of the Ca(V)3.2 (alpha1H) T-type Ca2+ channels.

CACNA1H CACNA1G

2.62e-06333221084288
Pubmed

Homeostatic plasticity and burst activity are mediated by hyperpolarization-activated cation currents and T-type calcium channels in neuronal cultures.

CACNA1H CACNA1G

2.62e-06333233547341
Pubmed

Electric field stimulation unmasks a subtle role for T-type calcium channels in regulating lymphatic contraction.

CACNA1H CACNA1G

2.62e-06333237739992
Pubmed

Calmodulin regulates Cav3 T-type channels at their gating brake.

CACNA1H CACNA1G

2.62e-06333228972185
Pubmed

Specific contribution of human T-type calcium channel isotypes (alpha(1G), alpha(1H) and alpha(1I)) to neuronal excitability.

CACNA1H CACNA1G

2.62e-06333211927664
Pubmed

Association of single nucleotide polymorphisms in CACNA 1A/CACNA 1C/CACNA 1H calcium channel genes with diabetic peripheral neuropathy in Chinese population.

CACNA1A CACNA1H

2.62e-06333229581247
Pubmed

ZnT-1 enhances the activity and surface expression of T-type calcium channels through activation of Ras-ERK signaling.

CACNA1H CACNA1G

2.62e-06333222572848
Pubmed

Genome-wide analysis of histidine repeats reveals their role in the localization of human proteins to the nuclear speckles compartment.

FAM76B POU4F2

2.62e-06333219266028
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

NR4A3 OTX1 PRICKLE3 ONECUT1 FOXG1 RNF111 MEOX2

3.83e-0670933722988430
Pubmed

Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.

NR4A3 OTX1 ONECUT1 FOXG1 MEOX2

4.75e-0626333520932939
Pubmed

CAST/ELKS Proteins Control Voltage-Gated Ca2+ Channel Density and Synaptic Release Probability at a Mammalian Central Synapse.

CACNA1A ERC2

5.23e-06433229996090
Pubmed

Pharmacogenetics of antiepileptic drug efficacy in childhood absence epilepsy.

CACNA1H CACNA1G

5.23e-06433228165634
Pubmed

Multiple Arkadia/RNF111 structures coordinate its Polycomb body association and transcriptional control.

CBX4 RNF111

5.23e-06433224912682
Pubmed

Phase-separation mechanism for C-terminal hyperphosphorylation of RNA polymerase II.

DYRK1A CCNT1

5.23e-06433229849146
Pubmed

T-type Ca2+ channels elicit pro-proliferative and anti-apoptotic responses through impaired PP2A/Akt1 signaling in PASMCs from patients with pulmonary arterial hypertension.

CACNA1H CACNA1G

5.23e-06433228655554
Pubmed

Role of the alpha1G T-type calcium channel in spontaneous absence seizures in mutant mice.

CACNA1A CACNA1G

5.23e-06433215175395
Pubmed

Deficient FGF signaling causes optic nerve dysgenesis and ocular coloboma.

POU4F2 OTX1 FOXG1

5.44e-063633323720040
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

DLGAP3 SORBS2 NCAN IQSEC2 SYNGAP1

6.55e-0628133528706196
Pubmed

Identification of 14-3-3epsilon substrates from embryonic murine brain.

DYRK1A ERC2 DLGAP3 SORBS2

7.45e-0613233416944949
Pubmed

Developmental expression patterns of alpha1H T-type Ca2+ channels during spermatogenesis and organogenesis in mice.

CACNA1H CACNA1G

8.72e-06533212060068
Pubmed

The mouse homolog of the orphan nuclear receptor tailless is expressed in the developing forebrain.

OTX1 FOXG1

8.72e-0653327720587
Pubmed

T-type calcium channels functionally interact with spectrin (α/β) and ankyrin B.

CACNA1H CACNA1G

8.72e-06533229720258
Pubmed

Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders.

DYRK1A ARID1B SYNGAP1

9.36e-064333336950384
Pubmed

Loss of zinc-finger protein 212 leads to Purkinje cell death and locomotive abnormalities with phospholipase D3 downregulation.

CACNA1A CACNA1G BEAN1

1.15e-054633334815492
Pubmed

A novel function of Onecut1 protein as a negative regulator of MafA gene expression.

ONECUT1 MAFA

1.31e-05633223775071
Pubmed

Flexible long-range loops in the VH gene region of the Igh locus facilitate the generation of a diverse antibody repertoire.

YY1 MEOX2

1.31e-05633223973221
Pubmed

Sox2 regulatory sequences direct expression of a (beta)-geo transgene to telencephalic neural stem cells and precursors of the mouse embryo, revealing regionalization of gene expression in CNS stem cells.

OTX1 FOXG1

1.31e-05633210804179
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

NR4A3 POU4F2 NKD2 PRICKLE3 YY1 FOXG1 MEOX2

1.53e-0587733720211142
Pubmed

BMP signaling is required for development of the ciliary body.

POU4F2 OTX1

1.83e-05733212223402
Pubmed

Foxg1 is required for proper separation and formation of sensory cristae during inner ear development.

OTX1 FOXG1

1.83e-05733219842177
Pubmed

Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.

CACNA1H CACNA1G

1.83e-05733212900400
Pubmed

Rebuilding essential active zone functions within a synapse.

CACNA1A ERC2

1.83e-05733235176221
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

DYRK1A USP34 ERC2 SORBS2 IQSEC2 RNF111 ZIC3 SYNGAP1

2.07e-05128533835914814
Pubmed

Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.

DYRK1A CCNT1 CBX4 NKD2 YY1

2.08e-0535733537059091
Pubmed

Evolutionary insights into T-type Ca2+ channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue.

CACNA1H CACNA1G

2.44e-05833228330839
Pubmed

Onecut 1 and Onecut 2 are potential regulators of mouse retinal development.

POU4F2 ONECUT1

2.44e-05833221830221
Pubmed

Neuroepithelial progenitors generate and propagate non-neuronal action potentials across the spinal cord.

CACNA1H CACNA1G

2.44e-05833234478646
Pubmed

Longitudinal organization of the anterior neural plate and neural tube.

OTX1 FOXG1

2.44e-0583328575293
Pubmed

Intracellular calcium plays an essential role in cardiac development.

CACNA1H CACNA1G

2.44e-05833212761855
Pubmed

Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors.

CACNA1A ERC2 FOXG1

2.57e-056033332027825
Pubmed

Genetic interactions support an inhibitory relationship between bone morphogenetic protein 2 and netrin 1 during semicircular canal formation.

NR4A3 FOXG1

3.13e-05933230770380
Pubmed

Foxg1 suppresses early cortical cell fate.

OTX1 FOXG1

3.13e-05933214704420
Pubmed

TBR1 regulates autism risk genes in the developing neocortex.

DYRK1A ARID1B

3.13e-05933227325115
Pubmed

Hmx2 homeobox gene control of murine vestibular morphogenesis.

OTX1 FOXG1

3.13e-05933211748138
Pubmed

Onecut Factors and Pou2f2 Regulate the Distribution of V2 Interneurons in the Mouse Developing Spinal Cord.

ONECUT1 MAFA

3.91e-051033231231191
Pubmed

Regionalisation of anterior neuroectoderm and its competence in responding to forebrain and midbrain inducing activities depend on mutual antagonism between OTX2 and GBX2.

OTX1 FOXG1

3.91e-051033211731459
Pubmed

Coordinate regulation and synergistic actions of BMP4, SHH and FGF8 in the rostral prosencephalon regulate morphogenesis of the telencephalic and optic vesicles.

OTX1 FOXG1

3.91e-051033211955708
Pubmed

Gata2 is required for the development of inner ear semicircular ducts and the surrounding perilymphatic space.

NR4A3 FOXG1

3.91e-051033220652952
Pubmed

Cav3.2 T-type calcium channel is required for the NFAT-dependent Sox9 expression in tracheal cartilage.

CACNA1H CACNA1G

3.91e-051033224778262
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

DYRK1A CACNA1A ERC2 DLGAP3 SORBS2 NCAN IQSEC2 SYNGAP1

4.46e-05143133837142655
Pubmed

Foxd1 is required for proper formation of the optic chiasm.

POU4F2 FOXG1

4.78e-051133215509772
Pubmed

Targeting HIV transcription: the quest for a functional cure.

CCNT1 YY1

4.78e-051133225731772
Pubmed

Vsx2 controls eye organogenesis and retinal progenitor identity via homeodomain and non-homeodomain residues required for high affinity DNA binding.

POU4F2 OTX1

5.73e-051233223028343
Pubmed

Myc cooperates with β-catenin to drive gene expression in nephron progenitor cells.

NKD1 NKD2

5.73e-051233228993399
Pubmed

Identification of candidate proteins binding to prion protein.

DLGAP3 YY1

5.73e-05123329173930
Pubmed

Differential requirements for FGF3, FGF8 and FGF10 during inner ear development.

FOXG1 MEOX2

5.73e-051233217601531
Pubmed

The iron exporter ferroportin 1 is essential for development of the mouse embryo, forebrain patterning and neural tube closure.

FOXG1 MEOX2

6.77e-051333220702562
Pubmed

Dbx1-expressing cells are necessary for the survival of the mammalian anterior neural and craniofacial structures.

OTX1 FOXG1

6.77e-051333221552538
Pubmed

Anterior visceral endoderm SMAD4 signaling specifies anterior embryonic patterning and head induction in mice.

FOXG1 MEOX2

6.77e-051333220941375
Pubmed

The protein kinase DYRK1A regulates caspase-9-mediated apoptosis during retina development.

DYRK1A POU4F2

6.77e-051333219081073
Pubmed

A targeted mutation of Nkd1 impairs mouse spermatogenesis.

NKD1 NKD2

7.89e-051433215546883
Pubmed

Multiple, temporal-specific roles for HNF6 in pancreatic endocrine and ductal differentiation.

ONECUT1 MAFA

7.89e-051433219766716
Pubmed

Visceral endoderm-restricted translation of Otx1 mediates recovery of Otx2 requirements for specification of anterior neural plate and normal gastrulation.

OTX1 FOXG1

7.89e-05143329811592
InteractionRNF4 interactions

DYRK1A FAM76B SLC39A6 USP34 CCNT1 ERC2 NR4A3 DLGAP3 ARID1B OTX1 CBX4 NKD1 NKD2 PRICKLE3 ONECUT1 YY1 FOXG1 IQSEC2 MAFA RNF111 ZIC3 SYNGAP1

1.12e-1814123222int:RNF4
InteractionKDM5B interactions

CACNA1A SLC39A6 NR4A3 CACNA1H ARID1B CBX4 FOXG1 MEOX2

2.63e-12100328int:KDM5B
InteractionFBLN5 interactions

DYRK1A FAM76B ARID1B OTX1 CBX4 FOXG1 RNF111 MEOX2

1.13e-10159328int:FBLN5
InteractionKRTAP9-8 interactions

NR4A3 POU4F2 OTX1 NKD1 YY1 MEOX2

1.05e-08100326int:KRTAP9-8
InteractionKRTAP5-9 interactions

FAM76B NR4A3 POU4F2 OTX1 NKD1 RNF111 MEOX2

2.58e-08203327int:KRTAP5-9
InteractionKRTAP5-11 interactions

FAM76B NR4A3 POU4F2 OTX1 MEOX2

6.07e-0866325int:KRTAP5-11
InteractionKRTAP12-3 interactions

NR4A3 POU4F2 OTX1 NKD1 YY1 MEOX2

1.01e-07146326int:KRTAP12-3
InteractionKRTAP4-5 interactions

FAM76B POU4F2 OTX1 YY1 MEOX2

1.24e-0776325int:KRTAP4-5
InteractionKRTAP10-1 interactions

FAM76B NR4A3 POU4F2 OTX1 NKD1 MEOX2

1.34e-07153326int:KRTAP10-1
InteractionKRTAP10-5 interactions

FAM76B NR4A3 POU4F2 OTX1 YY1 MEOX2

1.74e-07160326int:KRTAP10-5
InteractionGRN interactions

CACNA1A FAM76B CCNT1 POU4F2 OTX1 YY1 MEOX2

2.37e-07281327int:GRN
InteractionKRTAP4-11 interactions

FAM76B NR4A3 POU4F2 OTX1 MEOX2

3.25e-0792325int:KRTAP4-11
InteractionKRTAP5-6 interactions

NR4A3 POU4F2 OTX1 YY1 MEOX2

3.61e-0794325int:KRTAP5-6
InteractionPCSK5 interactions

CACNA1A NR4A3 POU4F2 OTX1 MEOX2

8.66e-07112325int:PCSK5
InteractionKRTAP12-4 interactions

NR4A3 POU4F2 OTX1 MEOX2

1.45e-0653324int:KRTAP12-4
InteractionKRTAP10-9 interactions

FAM76B POU4F2 OTX1 NKD1 YY1 MEOX2

1.92e-06241326int:KRTAP10-9
InteractionKRTAP4-2 interactions

NR4A3 POU4F2 OTX1 YY1 MEOX2

1.95e-06132325int:KRTAP4-2
InteractionKRTAP4-7 interactions

FAM76B OTX1 MEOX2

2.01e-0616323int:KRTAP4-7
InteractionKRTAP10-8 interactions

FAM76B NR4A3 POU4F2 OTX1 NKD1 YY1 MEOX2

2.57e-06401327int:KRTAP10-8
InteractionKRTAP9-3 interactions

NR4A3 POU4F2 OTX1 YY1 MEOX2

2.61e-06140325int:KRTAP9-3
InteractionKRTAP10-11 interactions

FAM76B POU4F2 OTX1 MEOX2

3.11e-0664324int:KRTAP10-11
InteractionKRTAP5-3 interactions

NR4A3 POU4F2 OTX1 MEOX2

3.52e-0666324int:KRTAP5-3
InteractionKRTAP9-2 interactions

FAM76B NR4A3 POU4F2 OTX1 MEOX2

3.54e-06149325int:KRTAP9-2
InteractionKRTAP4-4 interactions

NR4A3 POU4F2 OTX1 MEOX2

7.99e-0681324int:KRTAP4-4
InteractionCYSRT1 interactions

CACNA1A NR4A3 POU4F2 OTX1 NKD1 YY1 MEOX2

1.26e-05511327int:CYSRT1
InteractionCHRD interactions

NR4A3 POU4F2 OTX1 MEOX2

1.44e-0594324int:CHRD
InteractionFAM76B interactions

FAM76B CCNT1 CBX4 YY1

1.77e-0599324int:FAM76B
InteractionSPRY1 interactions

CACNA1A OTX1 YY1 MEOX2

2.78e-05111324int:SPRY1
InteractionVWC2L interactions

NR4A3 OTX1 MEOX2

3.45e-0540323int:VWC2L
InteractionCREBBP interactions

DYRK1A NR4A3 ARID1B CBX4 ONECUT1 YY1 RNF111

3.49e-05599327int:CREBBP
InteractionNELL1 interactions

DYRK1A CACNA1A MEOX2

4.00e-0542323int:NELL1
InteractionALPP interactions

NR4A3 POU4F2 OTX1 MEOX2

4.16e-05123324int:ALPP
InteractionEFEMP1 interactions

DYRK1A CACNA1A NR4A3 MEOX2

4.16e-05123324int:EFEMP1
InteractionKRTAP12-2 interactions

POU4F2 OTX1 YY1 MEOX2

4.86e-05128324int:KRTAP12-2
InteractionEFEMP2 interactions

DYRK1A CACNA1A OTX1 MEOX2

6.16e-05136324int:EFEMP2
InteractionARHGEF15 interactions

FAM76B CCNT1 YY1

6.38e-0549323int:ARHGEF15
InteractionSMAD3 interactions

DYRK1A ARID1B YY1 FOXG1 RNF111 MEOX2

6.39e-05447326int:SMAD3
InteractionTOX4 interactions

FAM76B CCNT1 CBX4 YY1

7.29e-05142324int:TOX4
InteractionRECK interactions

DYRK1A NR4A3 MEOX2

7.62e-0552323int:RECK
InteractionEIF5A interactions

FAM76B CCNT1 YY1 SYNGAP1 MEOX2

7.78e-05283325int:EIF5A
InteractionKPRP interactions

DYRK1A NR4A3 POU4F2 OTX1 MEOX2

7.91e-05284325int:KPRP
InteractionATXN2L interactions

FAM76B CCNT1 CBX4 YY1 SYNGAP1

8.18e-05286325int:ATXN2L
InteractionTRIM42 interactions

POU4F2 OTX1 YY1 MEOX2

8.78e-05149324int:TRIM42
InteractionMFAP1 interactions

DYRK1A FAM76B CCNT1 CBX4 YY1

9.46e-05295325int:MFAP1
InteractionEPB41L2 interactions

FAM76B CCNT1 ARID1B CBX4 SYNGAP1

1.01e-04299325int:EPB41L2
InteractionYWHAE interactions

DYRK1A ERC2 DLGAP3 SORBS2 CBX4 NKD2 PRICKLE3 IQSEC2 SYNGAP1

1.05e-041256329int:YWHAE
InteractionSHANK3 interactions

ERC2 DLGAP3 SORBS2 NCAN IQSEC2 SYNGAP1

1.13e-04496326int:SHANK3
InteractionSYNGAP1 interactions

DLGAP3 SORBS2 NCAN IQSEC2 SYNGAP1

1.14e-04307325int:SYNGAP1
InteractionKRTAP6-3 interactions

NR4A3 POU4F2 OTX1 MEOX2

1.19e-04161324int:KRTAP6-3
InteractionKRTAP4-12 interactions

FAM76B POU4F2 OTX1 MEOX2

1.19e-04161324int:KRTAP4-12
InteractionVWC2 interactions

POU4F2 OTX1 YY1

1.29e-0462323int:VWC2
InteractionKRTAP5-2 interactions

FAM76B DLGAP3 MEOX2

1.29e-0462323int:KRTAP5-2
InteractionPPIL4 interactions

FAM76B CCNT1 CBX4 YY1

1.30e-04165324int:PPIL4
InteractionSART1 interactions

FAM76B CCNT1 CBX4 YY1 SYNGAP1

1.33e-04317325int:SART1
InteractionKRTAP12-1 interactions

POU4F2 OTX1 MEOX2

1.35e-0463323int:KRTAP12-1
InteractionKRTAP5-4 interactions

POU4F2 OTX1 MEOX2

1.35e-0463323int:KRTAP5-4
InteractionTAF2 interactions

FAM76B CCNT1 CBX4 YY1

1.74e-04178324int:TAF2
InteractionPPP1R10 interactions

FAM76B CCNT1 CBX4 YY1

1.78e-04179324int:PPP1R10
InteractionDLGAP1 interactions

DLGAP3 SORBS2 IQSEC2 SYNGAP1

1.82e-04180324int:DLGAP1
InteractionCHIC2 interactions

POU4F2 OTX1 MEOX2

2.10e-0473323int:CHIC2
InteractionNALCN interactions

CACNA1A MEOX2

2.20e-0414322int:NALCN
InteractionNSRP1 interactions

FAM76B CCNT1 CBX4 YY1

2.57e-04197324int:NSRP1
InteractionTSC1 interactions

DYRK1A NKD2 FOXG1 NCAN SYNGAP1

2.59e-04366325int:TSC1
InteractionLCE4A interactions

OTX1 RNF111 MEOX2

2.75e-0480323int:LCE4A
InteractionPLSCR2 interactions

POU4F2 OTX1

2.89e-0416322int:PLSCR2
InteractionCBX4 interactions

FAM76B CCNT1 CBX4 YY1

2.99e-04205324int:CBX4
InteractionTNIK interactions

CACNA1A ERC2 SORBS2 IQSEC2 SYNGAP1

3.11e-04381325int:TNIK
InteractionDDX42 interactions

FAM76B CCNT1 CBX4 YY1

3.16e-04208324int:DDX42
InteractionSMAD2 interactions

DYRK1A ARID1B YY1 FOXG1 RNF111

3.26e-04385325int:SMAD2
InteractionLGALS13 interactions

POU4F2 OTX1

3.27e-0417322int:LGALS13
InteractionAGAP2 interactions

DLGAP3 SORBS2 IQSEC2 SYNGAP1

3.28e-04210324int:AGAP2
InteractionWDR82 interactions

FAM76B CCNT1 CBX4 YY1

3.46e-04213324int:WDR82
InteractionRB1 interactions

DYRK1A CCNT1 NR4A3 CBX4 YY1

3.63e-04394325int:RB1
InteractionFAM53B interactions

DYRK1A MEOX2

3.68e-0418322int:FAM53B
InteractionKRTAP1-1 interactions

FAM76B POU4F2 OTX1 RNF111

3.84e-04219324int:KRTAP1-1
InteractionCCNT1 interactions

FAM76B CCNT1 CBX4 YY1

4.26e-04225324int:CCNT1
InteractionFIP1L1 interactions

FAM76B CCNT1 CBX4 YY1

4.26e-04225324int:FIP1L1
InteractionMETTL17 interactions

FAM76B CCNT1 CBX4 YY1 MEOX2

4.40e-04411325int:METTL17
InteractionKRTAP2-3 interactions

OTX1 NKD1 YY1

4.56e-0495323int:KRTAP2-3
InteractionCOMP interactions

OTX1 MEOX2

4.56e-0420322int:COMP
InteractionKALRN interactions

CACNA1A IQSEC2 SYNGAP1

4.70e-0496323int:KALRN
InteractionDBN1 interactions

DYRK1A SORBS2 MAFA ZIC3 SYNGAP1

4.70e-04417325int:DBN1
InteractionFAM76A interactions

FAM76B YY1

5.03e-0421322int:FAM76A
InteractionCRIM1 interactions

DYRK1A CACNA1A

5.03e-0421322int:CRIM1
InteractionESM1 interactions

YY1 MEOX2

5.03e-0421322int:ESM1
InteractionMDFI interactions

OTX1 NKD1 YY1 RNF111 MEOX2

5.41e-04430325int:MDFI
InteractionKRTAP2-4 interactions

OTX1 NKD1 YY1

5.45e-04101323int:KRTAP2-4
InteractionRBM15B interactions

FAM76B CCNT1 YY1

5.45e-04101323int:RBM15B
InteractionSIAH2 interactions

CCNT1 PRICKLE3 SIAH3

5.94e-04104323int:SIAH2
InteractionDCAF13 interactions

FAM76B CCNT1 CBX4 YY1

6.05e-04247324int:DCAF13
InteractionCACNB2 interactions

CACNA1A SYNGAP1

6.05e-0423322int:CACNB2
InteractionNCAN interactions

NCAN SYNGAP1

6.60e-0424322int:NCAN
InteractionCSNK1D interactions

FAM76B CCNT1 CBX4 YY1

6.71e-04254324int:CSNK1D
InteractionCPSF1 interactions

FAM76B CCNT1 ARID1B YY1

6.81e-04255324int:CPSF1
InteractionKAT2B interactions

CCNT1 ONECUT1 YY1 MAFA

6.91e-04256324int:KAT2B
InteractionCDKL5 interactions

DLGAP3 IQSEC2 SYNGAP1

7.56e-04113323int:CDKL5
InteractionAKAP13 interactions

CCNT1 SORBS2 SYNGAP1

8.16e-04116323int:AKAP13
InteractionSATB1 interactions

CBX4 FOXG1 MEOX2

8.16e-04116323int:SATB1
InteractionB4GALT2 interactions

DYRK1A USP34 MEOX2

8.79e-04119323int:B4GALT2
InteractionPTK2B interactions

DLGAP3 SORBS2 SYNGAP1

8.79e-04119323int:PTK2B
CytobandEnsembl 112 genes in cytogenetic band chr2p15

USP34 OTX1

4.65e-0444332chr2p15
GeneFamilyCalcium voltage-gated channel subunits

CACNA1A CACNA1H CACNA1G

5.95e-0626253253
GeneFamilyForkhead boxes

FOXG1 FOXB2

1.60e-0343252508
CoexpressionBENPORATH_SUZ12_TARGETS

CACNA1A NR4A3 CACNA1G POU4F2 OTX1 NKD1 ONECUT1 FOXG1 SIAH3

3.69e-061035339M9898
CoexpressionBENPORATH_ES_WITH_H3K27ME3

CACNA1A NR4A3 CACNA1G POU4F2 OTX1 CBX4 ONECUT1 FOXG1 MEOX2

6.76e-061115339M10371
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500_k-means-cluster#4

SORBS2 FOXG1 NCAN ZIC3

3.61e-05121334Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500_K4
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#2

CACNA1H SORBS2 FOXG1 NCAN ZIC3

3.79e-05248335Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000_K2
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_500_k-means-cluster#2

SORBS2 FOXG1 NCAN ZIC3

7.32e-05145334Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_500_K2
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500

ERC2 OTX1 SORBS2 FOXG1 NCAN ZIC3

9.88e-05493336Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_500

NR4A3 OTX1 SORBS2 NKD1 NCAN ZIC3

1.02e-04496336Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000

CACNA1A ERC2 CACNA1H SORBS2 FOXG1 NCAN ZIC3 MEOX2

1.03e-04986338Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000

CACNA1A ERC2 NR4A3 OTX1 SORBS2 FOXG1 NCAN ZIC3

1.06e-04989338Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#5

CACNA1A ERC2 CACNA1H SORBS2 FOXG1 NCAN ZIC3

1.10e-04732337Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_2500_K5
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#3_top-relative-expression-ranked_1000

SORBS2 NKD1 NKD2

1.53e-0467333gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000_k3
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#1

SORBS2 FOXG1 NCAN ZIC3

1.58e-04177334Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K1
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000_k-means-cluster#3

CACNA1H SORBS2 FOXG1 NCAN ZIC3

1.66e-04339335Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000_K3
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_500_k-means-cluster#2

SORBS2 NCAN ZIC3

1.82e-0471333Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_500_K2
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

SORBS2 FOXG1 NCAN ZIC3 SKIDA1

1.92e-04350335Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K5
CoexpressionAtlasBM Top 100 - amygdala

ERC2 FOXG1 NCAN

1.97e-0473333BM Top 100 - amygdala
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

SORBS2 FOXG1 NCAN ZIC3

2.34e-04196334Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_1000_K2
CoexpressionAtlascerebral cortex

CACNA1A ERC2 DLGAP3 CACNA1G OTX1 FOXG1 NCAN ZIC3 SYNGAP1

2.42e-041428339cerebral cortex
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#2

SORBS2 FOXG1 ZIC3

2.50e-0479333Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K2
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000_k-means-cluster#5

SORBS2 FOXG1 NCAN ZIC3

3.15e-04212334Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000_K5
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_500_k-means-cluster#4

SORBS2 NCAN ZIC3

3.66e-0490333Facebase_RNAseq_e8.5_Floor Plate_500_K4
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_2500_k-means-cluster#3

CACNA1A ERC2 CACNA1H SORBS2 FOXG1 NCAN ZIC3

3.72e-04893337Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_2500_K3
CoexpressionAtlasFacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_1000_k-means-cluster#4

CACNA1A ERC2 CACNA1H FOXG1

3.82e-04223334Facebase_RNAseq_e9.5_Facial Mesenchyne_1000_K4
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#1

SLC39A6 SORBS2 FOXG1 NCAN ZIC3

4.40e-04419335Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K1
CoexpressionAtlasFacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#4

CACNA1A ERC2 CACNA1H ZIC3

4.43e-04232334Facebase_RNAseq_e9.5_Maxillary Arch_1000_K4
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_100

FOXG1 NCAN ZIC3

4.85e-0499333Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_100
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_100

OTX1 FOXG1 ZIC3

4.99e-04100333Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_100
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#3

CACNA1H SORBS2 FOXG1 NCAN ZIC3

5.90e-04447335Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K3
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000

CACNA1H CACNA1G OTX1 SORBS2 FOXG1 NCAN ZIC3

6.34e-04976337Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000

CACNA1A ERC2 OTX1 SORBS2 FOXG1 NCAN ZIC3

6.62e-04983337Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_500_k-means-cluster#3

FOXG1 NCAN ZIC3

8.08e-04118333Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_500_K3
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_500

OTX1 SORBS2 FOXG1 NCAN ZIC3

8.84e-04489335Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_500
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000_k-means-cluster#2

SORBS2 NCAN ZIC3

8.90e-04122333Facebase_RNAseq_e8.5_Floor Plate_1000_K2
CoexpressionAtlasFacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#5

CACNA1A ERC2 FOXG1

9.33e-04124333Facebase_RNAseq_e10.5_Medial Nasal Eminence_1000_K5
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_500

NR4A3 OTX1 SORBS2 NCAN ZIC3

9.34e-04495335Facebase_RNAseq_e8.5_Floor Plate_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500

ERC2 OTX1 SORBS2 FOXG1 ZIC3

9.59e-04498335Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#1

SORBS2 NCAN ZIC3

1.00e-03127333Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000_K1
ToppCellRV-13._Vascular_Smooth_Muscle|RV / Chamber and Cluster_Paper

CACNA1A CACNA1H NKD1 MEOX2

5.96e-0616133447b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCellBAL-Mild-cDC_0|Mild / Compartment, Disease Groups and Clusters

ERC2 DLGAP3 IQSEC2 SYNGAP1

6.26e-061633347047d3ba847930f42a6d5f71e18d49f3071c6409
ToppCellRA-07._Pericyte|RA / Chamber and Cluster_Paper

CACNA1A DLGAP3 CACNA1H MEOX2

9.46e-061813348dfb42d096db6c2df9b41303a7199d134d4bff07
ToppCellRA-07._Pericyte|World / Chamber and Cluster_Paper

CACNA1A DLGAP3 CACNA1H MEOX2

9.67e-061823342075efeae633550fb2eb026d0dfd741c8252482e
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1H CACNA1G SORBS2 NKD1

1.03e-0518533430df02fbe2828e3c4f3e5c4cda855e74fb31be39
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1H CACNA1G SORBS2 NKD1

1.08e-051873348ff9f771d10c372d771c92dfa9006aa81aec4681
ToppCellMesenchymal_cells-Smooth_muscle|World / Lineage and Cell class

CACNA1H SORBS2 NKD1 MEOX2

1.15e-051903345aa62a363a25f4a110136263b21289a11e8c1e6d
ToppCell(09)_Ionocytes-(3)_72hpi|(09)_Ionocytes / shred by cell type and Timepoint

SORBS2 NKD1 YY1

7.35e-05110333fce7d5a0617fc664b657f5bb9abb290e7cc234cb
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DLGAP3 ONECUT1 MEOX2

1.21e-041303331720f16ac06951c3f57b6c3b0944670a571203d1
ToppCellRA-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

ERC2 NR4A3 SORBS2

1.44e-041383335a713f24f633de463ef47ca37fbb2bb60c7fdb77
ToppCellfacs-Marrow-KLS-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1G BEAN1 MEOX2

2.15e-041583330edd9b005875f9a4f5446f5d5161f8ba63860793
ToppCellfacs-Marrow-KLS-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1G BEAN1 MEOX2

2.15e-041583339fd77ebdd1babf1c85a85d38d9a15858ab08bc84
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ERC2 NR4A3 DLGAP3

2.19e-041593332f6c60ddff2208a68146f9786143d9aefd528840
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ERC2 NR4A3 DLGAP3

2.19e-04159333ded4e3626a62fb6334403b7213b467fb7e8131c3
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1H CACNA1G SIAH3

2.31e-04162333966df4558140c3d541999ab553f201ae76a1c401
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1H CACNA1G SIAH3

2.31e-0416233322f1abd20f43bc7e7fc46969da9962faf70ae5d2
ToppCellLV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

CACNA1A SORBS2 MEOX2

2.44e-04165333f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NR4A3 OTX1 ONECUT1

2.52e-04167333774f3264318b002d0df5d06d41d645366038d0bf
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A OTX1 MAFA

2.57e-041683330f736d58cb0ff042fa3ce58e36bde37b6976f8fc
ToppCell-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

NKD1 NKD2 MEOX2

2.61e-041693338ebe9a88111c53a09c25a7b6a164a0a17880458d
ToppCellMild_COVID-19-Myeloid-MoAM5|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

NR4A3 NKD1 MAFA

2.66e-04170333b2daf46ab5a49590ede8f75e4240bfe6e9d8b764
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ERC2 DLGAP3 SIAH3

2.85e-04174333271c51d220842402975d97c86c9acfdbdf62a32c
ToppCellfacs-Heart-LV-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1H CACNA1G SORBS2

2.85e-04174333197686570cec6d96a92e77e6409325d3bfe6f991
ToppCellfacs-Heart-LV-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1H CACNA1G SORBS2

2.85e-041743332eee7b5471672b439f95eba11494c2adf8cb7006
ToppCell5'-Adult-LymphNode-Mesenchymal-Pericytes|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1H SORBS2 MEOX2

2.90e-04175333798f33bd340261c048b7b45c842b2ccd1ea1fb60
ToppCell5'-Adult-LymphNode-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1H SORBS2 MEOX2

2.90e-04175333294a70786260c9a2b1ba16c88819d786698609e7
ToppCell3'-Adult-LargeIntestine-Epithelial-neuro-epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A CACNA1H MAFA

3.09e-04179333f93e81a3fd94adedb24a9db4ac1d53e275bbf8b5
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid-pDC|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC39A6 NR4A3 OTX1

3.09e-04179333bbd4f8e988ef3f343aaedbc992b70f2bb6aff5f6
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NKD1 NKD2 MEOX2

3.15e-041803339b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NKD1 NKD2 MEOX2

3.15e-0418033308ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-2|TCGA-Skin / Sample_Type by Project: Shred V9

SLC39A6 NR4A3 ONECUT1

3.20e-041813339d5b331cabc5524f0a9fd8b571e87be4c447c7d4
ToppCellVE-matDC-|VE / Condition, Cell_class and T cell subcluster

ERC2 NR4A3 BEAN1

3.20e-041813336252184ef098b911df50be4fe1b5565849a5b6b8
ToppCellVE-matDC|VE / Condition, Cell_class and T cell subcluster

ERC2 NR4A3 BEAN1

3.20e-04181333982fd96ef75bc9ab2c2f4970c01b76ba7a164871
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

CACNA1A NKD1 MEOX2

3.30e-04183333818fd886e0188091310825f9145fa53328f2c979
ToppCellCV-Healthy-7|CV / Virus stimulation, Condition and Cluster

CCNT1 NR4A3 RNF111

3.35e-041843330e5cc77aaa73ceb791f8be7456177577fd2e5586
ToppCellMesenchymal_cells-Smooth_muscle|Mesenchymal_cells / Lineage and Cell class

CACNA1H SORBS2 NKD1

3.35e-0418433383987abaedc26e6da477bc70d65e10b1ab1aea60
ToppCellCV-Healthy-7|Healthy / Virus stimulation, Condition and Cluster

CCNT1 NR4A3 RNF111

3.41e-041853331979d189c204f4c2893e3170a514ee7d5523406c
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC39A6 NKD1 NKD2

3.41e-04185333ca69499ba8c39b7ed6717d05685d6f70066a77bd
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A ERC2 DLGAP3

3.46e-041863337278a1a1bf9bb27aeb03852134defb31b62f30d6
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CACNA1G NKD1 NKD2

3.52e-041873335258674d0346e5c51a4b965efcdc1790c970845d
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D175|Adult / Lineage, Cell type, age group and donor

NKD1 NKD2 MEOX2

3.52e-04187333e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

NKD1 NKD2 MEOX2

3.52e-0418733392d468dde81125d51daf7abd4703741abe1ab91c
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

DYRK1A USP34 ARID1B

3.57e-04188333ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

OTX1 SORBS2 FOXG1

3.68e-041903336ea9fa08bd97bedcb21d3654467e7f8dd74c8fd0
ToppCellControl-Stromal_mesenchymal|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NKD1 NKD2 MEOX2

3.74e-0419133314057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-smooth_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1H SORBS2 NKD1

3.74e-041913338e8beb8e8a3b33cac83d3f7ce915a71e3654fdab
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1H SORBS2 NKD1

3.74e-0419133360bc1f3efa7bbad5cb7944fe5e049ea79cd1745a
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Stroma____kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1H SORBS2 NKD1

3.74e-041913338597a8af294f24496c317d995f07eb5dcc25c13c
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NKD1 NKD2 MEOX2

3.74e-041913336688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NKD1 NKD2 MEOX2

3.80e-0419233399ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NKD1 NKD2 MEOX2

3.80e-04192333deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

DYRK1A ARID1B NKD1

3.86e-04193333e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

NKD1 NKD2 MEOX2

3.86e-04193333acad568621ed677031797b8c2e34dafea798d681
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A ERC2 DLGAP3

3.86e-04193333be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

USP34 ARID1B RNF111

3.86e-04193333779276e775cb2492e8dd36436295a536084a6415
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A ERC2 DLGAP3

3.86e-041933330c652ebe22ce5d2927599dd97ef1920547858395
ToppCelldroplet-Limb_Muscle-nan-24m-Mesenchymal-smooth_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1H SORBS2 NKD1

3.86e-04193333b9e11cd0896c0868aab7faec4ab7ab4d4e4d1b47
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A ERC2 DLGAP3

3.86e-041933338689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

NKD1 NKD2 MEOX2

3.86e-0419333399525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D231|Adult / Lineage, Cell type, age group and donor

NKD1 NKD2 MEOX2

3.86e-04193333ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NKD1 NKD2 MEOX2

3.92e-0419433335f132cc38ac133be01834ed0946188aa0757eb4
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-smooth_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1H SORBS2 NKD1

3.92e-04194333b8a130ffae68ffe550bf335460a1ec1035cf8d8d
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

NKD1 NKD2 MEOX2

3.92e-04194333e93de9428c986b8943fc169258847c650cfab0e5
ToppCellControl-Stromal-Myofibroblast|World / Disease state, Lineage and Cell class

NKD1 NKD2 MEOX2

3.92e-041943333c2266772c5b56e8e02a461e5193e29588028ee9
ToppCellControl-Stromal-Myofibroblast|Control / Disease state, Lineage and Cell class

NKD1 NKD2 MEOX2

3.97e-04195333ffcf76cd72e43d8cf1058a49c76e0956065038bc
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell|Adult / Lineage, Cell type, age group and donor

NKD1 NKD2 MEOX2

3.97e-0419533361c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

NKD1 NKD2 MEOX2

3.97e-04195333603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Smooth_muscle|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CACNA1H SORBS2 NKD1

3.97e-04195333b3660779f274ca97dd844cf83f62d85ba88cb182
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NKD1 NKD2 MEOX2

3.97e-041953334243190ad291d56694e2155954dbaa879c9d3844
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Smooth_muscle-Smooth_muscle_L.2.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CACNA1H SORBS2 NKD1

3.97e-041953337155cc12cc6a97efd626bbdb95249fb3d7041dcf
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D122|Adult / Lineage, Cell type, age group and donor

NKD1 NKD2 MEOX2

3.97e-04195333aa0add081881d349099d12efca5cdee098038d4e
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1H SORBS2 NKD1

3.97e-041953330bdf845939bc4b8cc94f2808aea60f818425b076
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NKD1 NKD2 MEOX2

3.97e-04195333df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell5'-Adult-SmallIntestine-Mesenchymal-Pericytes|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1H SORBS2 NKD1

4.03e-041963336d7179decea512dd49bb2d5f6a4f5989349d52a9
ToppCell367C-Fibroblasts-Fibroblast-K_(Pericytes)|367C / Donor, Lineage, Cell class and subclass (all cells)

CACNA1H SORBS2 NKD1

4.03e-04196333c390ef0adff35111989a30dff86b7c5db1a89873
ToppCelldroplet-Bladder-nan-24m-Endothelial|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1H SORBS2 MEOX2

4.03e-041963339a90dd26e7a43e3fd55e7c5d8354cfa4cdd5a6cc
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NKD1 NKD2 MEOX2

4.03e-0419633342e9828222a9663525d571633e8a454c30bfa7f8
ToppCell367C-Fibroblasts-Fibroblast-K_(Pericytes)-|367C / Donor, Lineage, Cell class and subclass (all cells)

CACNA1H SORBS2 NKD1

4.03e-041963332f76f050083483f0880639e6c34ff349caac3503
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NKD1 NKD2 MEOX2

4.03e-04196333cecf82cd5e0a3835d655f5e7478578674a63ce25
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NKD1 NKD2 MEOX2

4.03e-041963339737a5f006d37b549f281e1863aca558e1e4dc99
ToppCellChildren_(3_yrs)-Mesenchymal|Children_(3_yrs) / Lineage, Cell type, age group and donor

NKD1 NKD2 MEOX2

4.03e-04196333bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCelldroplet-Bladder-nan-24m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1H SORBS2 MEOX2

4.03e-0419633304dfef1bd4ebb0e9469ae80024dc177e469a2560
ToppCellPericytes|World / shred by cell class for parenchyma

CACNA1H SORBS2 NKD1

4.03e-041963338e7ecbe77d312a7fc6aadd8fd52c13dd1834cc7e
ToppCell5'-Adult-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1H SORBS2 NKD1

4.03e-04196333ce6f7ddb8104471dc90347f427486379914d63b4
ToppCellnucseq-Mesenchymal-Fibroblastic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NKD1 NKD2 MEOX2

4.03e-041963337d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NKD1 NKD2 MEOX2

4.09e-0419733394a9603cbd3516fbcce871909693b88f20d41713
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NKD1 NKD2 MEOX2

4.09e-0419733313896ec65ccda0b928c91d41112dc01b480036b7
ToppCelldroplet-Bladder-nan-24m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1H SORBS2 MEOX2

4.09e-04197333488e85991c5e668afb7672942726d9295b8fc7d8
ToppCell5'-Adult-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1H SORBS2 NKD1

4.09e-04197333d16bb765afdc02406ffd7ce6a75bae72b66db66c
ToppCell5'-Adult-LargeIntestine-Mesenchymal-Pericytes|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1H SORBS2 NKD1

4.09e-0419733368c23c23b6924892f4c238cf2f5abc7927e04fbc
ToppCellBronchial-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1H SORBS2 NKD1

4.16e-04198333705118a5db366b43ffd3389c60e4cb392ad3f2e6
ToppCellcellseq-Mesenchymal-Myocytic-Myocytic_2-VSMC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNA1H SORBS2 NKD1

4.16e-04198333e967c601101361fc1c48dab0e5b76dc68813276e
ToppCellnucseq-Mesenchymal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NKD1 NKD2 MEOX2

4.16e-041983338f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1A ERC2 SORBS2

4.16e-041983336d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-ventral_progenitors_and_neurons_2|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

FOXG1 NCAN SIAH3

4.16e-04198333b73b9feb82997b654718aa27f33ca7b454214802
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1A ERC2 SORBS2

4.16e-04198333c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

NKD1 NKD2 MEOX2

4.16e-041983333ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCellAdult-Mesenchymal|Adult / Lineage, Cell type, age group and donor

NKD1 NKD2 MEOX2

4.16e-0419833326e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ERC2 CACNA1H NKD1

4.16e-041983331e1ea54f0c234f3b6d29064c4881d8a0c0949a75
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NKD1 NKD2 MEOX2

4.16e-04198333f1374f7a50244d59c766ac41f44c08c9117407d2
ComputationalGenes in the cancer module 98.

DYRK1A CCNT1 CBX4 YY1 FOXG1

4.84e-04393195MODULE_98
ComputationalTFs and nuclear.

DYRK1A CCNT1 CBX4 FOXG1

6.88e-04237194MODULE_252
ComputationalGenes in the cancer module 198.

DYRK1A CCNT1 CBX4 FOXG1

1.72e-03303194MODULE_198
ComputationalGenes in the cancer module 11.

CACNA1A SLC39A6 SORBS2 FOXG1 NCAN

2.03e-03540195MODULE_11
ComputationalGenes in the cancer module 100.

CACNA1A SLC39A6 SORBS2 FOXG1 NCAN

2.10e-03544195MODULE_100
ComputationalCNS genes.

CACNA1A SLC39A6 SORBS2 FOXG1 NCAN

2.13e-03546195MODULE_137
ComputationalGenes in the cancer module 66.

CACNA1A SLC39A6 SORBS2 FOXG1 NCAN

2.24e-03552195MODULE_66
ComputationalGenes in the cancer module 197.

CBX4 YY1 FOXG1

3.34e-03174193MODULE_197
Drug3,4-dihydroquinazoline

CACNA1A CACNA1H CACNA1G

5.53e-086333CID000583065
DrugAC1L2VU3

CACNA1A CACNA1H CACNA1G

6.05e-0712333CID000129572
Drugenzacamene

CACNA1A DLGAP3 CACNA1H CACNA1G SYNGAP1

1.13e-06129335ctd:C038939
Drugpentasulfane

CACNA1A CACNA1H CACNA1G

1.53e-0616333CID000448216
Drugoctylmethoxycinnamate

CACNA1A DLGAP3 CACNA1H CACNA1G SYNGAP1

1.63e-06139335ctd:C118580
Drugprocymidone

CACNA1A DLGAP3 CACNA1G NCAN SYNGAP1

2.79e-06155335ctd:C035988
Drugbutylparaben

CACNA1A DLGAP3 CACNA1H CACNA1G SYNGAP1

2.97e-06157335ctd:C038091
Drug1,3-dioxoisoindoline-5-carboxamide

CACNA1H CACNA1G

6.11e-063332CID010679219
DrugCNS 1145

CACNA1A CACNA1H CACNA1G

1.47e-0533333CID000190902
DrugIHC-64

CACNA1A CACNA1H CACNA1G

1.47e-0533333CID000162753
Drugloperamide

CACNA1A CACNA1H CACNA1G SORBS2

1.58e-05105334CID000003954
DrugFlunarizine

CACNA1H CACNA1G

2.03e-055332DB04841
DrugLinuron

CACNA1A DLGAP3 CACNA1G SYNGAP1

3.44e-05128334ctd:D008044
DrugLY215840

CACNA1H CACNA1G

4.26e-057332CID000132049
DrugKW-3049

CACNA1A CACNA1H CACNA1G

5.19e-0550333CID000002324
Drugisovalerate

CACNA1A CACNA1H CACNA1G ZIC3

5.30e-05143334CID000010430
Drugnimodipine

CACNA1A SLC39A6 CACNA1H CACNA1G

5.59e-05145334CID000004497
DrugBepridil

CACNA1A CACNA1H

5.67e-058332DB01244
DrugCinnarizine

CACNA1H CACNA1G

7.29e-059332DB00568
DrugCinildipine

CACNA1A CACNA1H CACNA1G

7.30e-0556333CID000002752
Drugnilvadipine

CACNA1A CACNA1H CACNA1G

8.97e-0560333CID000004494
Drughydroxyephedrine

RNF111 ZIC3

9.10e-0510332CID000009701
DrugIAA-94

CACNA1A CACNA1H CACNA1G

9.43e-0561333CID000003667
Druggabapentin

CACNA1A CACNA1H CACNA1G FOXG1

1.01e-04169334CID000003446
Druglercanidipine

CACNA1A CACNA1H CACNA1G

1.04e-0463333CID000065866
DrugMibefradil

CACNA1H CACNA1G

1.11e-0411332DB01388
DrugEBNs

CACNA1H CACNA1G

1.11e-0411332CID000150695
DrugAC1L1TJF

CACNA1A CACNA1H CACNA1G

1.19e-0466333CID000003377
DrugMethoxychlor

CACNA1A NR4A3 POU4F2 ONECUT1 SYNGAP1 FOXB2

1.22e-04549336ctd:D008731
Druggallopamil

CACNA1A CACNA1H CACNA1G

1.25e-0467333CID000001234
Drugthemisone

CACNA1H CACNA1G

1.33e-0412332CID000016235
DrugAC1L2AC7

CACNA1A CACNA1H CACNA1G

1.36e-0469333CID000068733
DrugBarium

CACNA1A CACNA1H CACNA1G

1.55e-0472333ctd:D001464
Drugtetralol

CACNA1H CACNA1G

1.57e-0413332CID000010747
DrugMibefradil

CACNA1H CACNA1G

1.57e-0413332ctd:D020748
Drugguanosine 3',5'-cyclic monophosphoric acid

CACNA1A CACNA1H CACNA1G CBX4 YY1 ZIC3

1.60e-04577336CID000000295
DrugCAS 298-57-7

CACNA1A CACNA1H CACNA1G

1.61e-0473333CID000002761
Drugethosuximide

CACNA1A CACNA1H CACNA1G

1.68e-0474333CID000003291
DrugStreptozotocin [18883-66-4]; Up 200; 15uM; PC3; HT_HG-U133A

CBX4 YY1 FOXG1 IQSEC2

1.72e-041943345836_UP
DrugOmeprazole [73590-58-6]; Up 200; 11.6uM; MCF7; HT_HG-U133A

CACNA1A USP34 CACNA1H PRICKLE3

1.72e-041943342828_UP
DrugDecamethonium bromide [541-22-0]; Down 200; 9.6uM; MCF7; HT_HG-U133A

DYRK1A POU4F2 ONECUT1 ZIC3

1.72e-041943344174_DN
DrugDihydroergocristine mesylate [24730-10-7]; Up 200; 5.6uM; MCF7; HT_HG-U133A

USP34 CACNA1H FOXG1 IQSEC2

1.76e-041953342895_UP
DrugClomiphene citrate (Z,E) [50-41-9]; Up 200; 6.6uM; MCF7; HT_HG-U133A

USP34 FOXG1 NCAN IQSEC2

1.76e-041953342624_UP
DrugGSK-3 Inhibitor IX; Up 200; 0.5uM; MCF7; HT_HG-U133A

USP34 CACNA1H PRICKLE3 IQSEC2

1.76e-041953347101_UP
Drug(S)-propranolol hydrochloride [4199-10-4]; Up 200; 13.6uM; HL60; HT_HG-U133A

DYRK1A CACNA1A NR4A3 FOXG1

1.79e-041963342961_UP
DrugDizocilpine maleate [77086-22-7]; Down 200; 11.8uM; MCF7; HT_HG-U133A

CACNA1A CACNA1H PRICKLE3 IQSEC2

1.79e-041963342232_DN
DrugLisinopril [83915-83-7]; Up 200; 9uM; HL60; HT_HG-U133A

DYRK1A ERC2 ONECUT1 FOXG1

1.83e-041973342371_UP
DrugFludrocortisone acetate [514-36-3]; Down 200; 9.4uM; MCF7; HT_HG-U133A

ONECUT1 YY1 FOXG1 ZIC3

1.83e-041973342328_DN
DrugNi-B

DYRK1A BEAN1

1.83e-0414332CID000039502
DrugTrapidil [15421-84-8]; Up 200; 19.4uM; MCF7; HT_HG-U133A

CACNA1A USP34 CACNA1H FOXG1

1.86e-041983347475_UP
DrugAceclofenac [89796-99-6]; Down 200; 11.2uM; MCF7; HT_HG-U133A

PRICKLE3 YY1 FOXG1 IQSEC2

1.86e-041983342281_DN
DrugLasalocid sodium salt [25999-20-6]; Down 200; 6.6uM; MCF7; HT_HG-U133A

USP34 CACNA1H POU4F2 ZIC3

1.90e-041993343360_DN
Drugnisoldipine

CACNA1A CACNA1H CACNA1G

1.96e-0478333CID000004499
DrugN-cyclopentyl-N-cyclobutylformamide

CACNA1A CACNA1H CACNA1G

2.04e-0479333CID005287890
Drugbutamben

CACNA1A CACNA1H

2.11e-0415332CID000002482
DrugVerapamil

CACNA1A CACNA1G

2.41e-0416332DB00661
Drugdifluoroboron

CACNA1A ONECUT1 FOXG1

2.44e-0484333CID000139622
DrugZonisamide

CACNA1H CACNA1G

2.73e-0417332DB00909
Drugcyclopropanecarboxylic acid

CACNA1H CACNA1G

3.43e-0419332CID000015655
Drugmanidipine

CACNA1A CACNA1H CACNA1G

3.51e-0495333CID000004008
Drugisotetrandrine

CACNA1A CACNA1H CACNA1G

3.73e-0497333CID000005422
Drughomovanillic acid

CACNA1A CACNA1H CACNA1G

3.73e-0497333CID000001738
Drugnitrendipine

CACNA1A CACNA1H CACNA1G

3.84e-0498333CID000004507
Drugisradipine

CACNA1A CACNA1H CACNA1G

4.08e-04100333CID000003784
Drugstannous ion

CBX4 FOXG1

4.20e-0421332CID000104883
Drugpyraclofos

CACNA1A CACNA1H CACNA1G

4.83e-04106333CID000093460
DiseaseEpilepsy, Cryptogenic

DYRK1A ARID1B FOXG1 IQSEC2 SYNGAP1

3.27e-0882335C0086237
DiseaseAwakening Epilepsy

DYRK1A ARID1B FOXG1 IQSEC2 SYNGAP1

3.27e-0882335C0751111
DiseaseAura

DYRK1A ARID1B FOXG1 IQSEC2 SYNGAP1

3.27e-0882335C0236018
DiseaseNeurodevelopmental Disorders

DYRK1A ARID1B FOXG1 IQSEC2 SYNGAP1

6.17e-0893335C1535926
DiseaseEpilepsy

DYRK1A ARID1B FOXG1 IQSEC2 SYNGAP1

1.37e-07109335C0014544
DiseaseMental Retardation, Psychosocial

CACNA1G YY1 FOXG1 SYNGAP1

1.74e-05139334C0025363
DiseaseProfound Mental Retardation

CACNA1G YY1 FOXG1 SYNGAP1

1.74e-05139334C0020796
DiseaseMental deficiency

CACNA1G YY1 FOXG1 SYNGAP1

1.74e-05139334C0917816
DiseaseAbsence Epilepsy

CACNA1A CACNA1H

2.54e-057332C0014553
DiseaseAkinetic Petit Mal

CACNA1A CACNA1H

2.54e-057332C0001890
DiseaseEpilepsy, Absence, Atypical

CACNA1A CACNA1H

2.54e-057332C0751124
DiseaseChildhood Absence Epilepsy

CACNA1A CACNA1H

2.54e-057332C4281785
DiseaseAbsence Seizure Disorder

CACNA1A CACNA1H

2.54e-057332C4553705
DiseaseJuvenile Absence Epilepsy

CACNA1A CACNA1H

2.54e-057332C4317339
DiseaseEpilepsy, Minor

CACNA1A CACNA1H

2.54e-057332C4552765
Diseasecortical surface area measurement

CACNA1A FAM76B USP34 ERC2 ARID1B FOXG1 SKIDA1 SIAH3

9.13e-051345338EFO_0010736
Diseaseintellectual disability (is_implicated_in)

DYRK1A ARID1B

5.17e-0430332DOID:1059 (is_implicated_in)
DiseaseEpileptic encephalopathy

CACNA1A SYNGAP1

5.17e-0430332C0543888
Diseaseautism spectrum disorder (implicated_via_orthology)

DYRK1A ARID1B SYNGAP1

6.53e-04152333DOID:0060041 (implicated_via_orthology)
DiseaseAtaxia, Spinocerebellar

CACNA1A CACNA1G

6.65e-0434332C0087012
DiseaseSpinocerebellar Ataxia Type 2

CACNA1A CACNA1G

6.65e-0434332C0752121
DiseaseSpinocerebellar Ataxia Type 1

CACNA1A CACNA1G

6.65e-0434332C0752120
DiseaseSpinocerebellar Ataxia Type 5

CACNA1A CACNA1G

6.65e-0434332C0752123
DiseaseSpinocerebellar Ataxia Type 7

CACNA1A CACNA1G

6.65e-0434332C0752125
DiseaseSpinocerebellar Ataxia Type 6 (disorder)

CACNA1A CACNA1G

6.65e-0434332C0752124
DiseaseSpinocerebellar Ataxia Type 4

CACNA1A CACNA1G

7.05e-0435332C0752122
Diseasediet measurement

ERC2 CACNA1H ARID1B OTX1 ONECUT1 SKIDA1

9.68e-041049336EFO_0008111

Protein segments in the cluster

PeptideGeneStartEntry
KHRQHHHHHHHHHHP

CACNA1A

2206

O00555
QHHHHHHAHHHHHHA

ARID1B

166

Q8NFD5
HHAHHHHHHAHHLHH

ARID1B

171

Q8NFD5
HHHHAHHLHHHHALQ

ARID1B

176

Q8NFD5
NHHHHHNHHSHKHSH

CCNT1

516

O60563
HHGNSSHHHHHHHHH

DYRK1A

601

Q13627
SHHHHHHHHHHHHHG

DYRK1A

606

Q13627
RHEHHHHHEHHHHYH

NKD1

451

Q969G9
HHHPHHHHHHHAAAH

FOXB2

141

Q5VYV0
HHHHHHAAAHHHHHH

FOXB2

146

Q5VYV0
AAHHHHAAHHHHHHH

MAFA

191

Q8NHW3
HAAHHHHHHHHHHGG

MAFA

196

Q8NHW3
SSTHHHHHHHHHGHS

IQSEC2

1236

Q5JU85
NSHHPQHHHHHHHHH

FOXG1

41

P55316
HHHHHHHHHPHHHQR

ONECUT1

126

Q9UBC0
QHHPKHHHHHHHHHH

FAM76B

166

Q5HYJ3
HHHHHHHHHHRHSSS

FAM76B

171

Q5HYJ3
ASQHHRGHHHHHHHH

MEOX2

61

P50222
RGHHHHHHHHHHHHH

MEOX2

66

P50222
HHHHHHHHHHQQQQH

MEOX2

71

P50222
HHYHHHHHHHHHRSP

ERC2

921

O15083
HEHHHHHEHHHHHHH

NKD2

431

Q969F2
HHEHHHHHHHHHFHP

NKD2

436

Q969F2
GHHHHHHHHHHQGYG

OTX1

291

P32242
RRHHHHNHHHHHNRH

PRICKLE3

511

O43900
VHHLVHHHHHHHHHY

CACNA1G

491

O43497
HHHHHHHHHYHLGNG

CACNA1G

496

O43497
TSHHHHHHHHHHHHQ

DLGAP3

221

O95886
HHHHHHHHHQSRHGK

DLGAP3

226

O95886
PHPHHHHHHHHHHHH

CBX4

386

O00257
HHHHHHHHHHAVGLN

CBX4

391

O00257
RHRHHRHHHHHHHHR

BEAN1

71

Q3B7T3
HLVYHHHHHHHHHYH

CACNA1H

516

O95180
HHHHHHHHYHFSHGS

CACNA1H

521

O95180
APSYHHHHHHHHHHH

NR4A3

91

Q92570
HHHHHHHHHHHHHQQ

NR4A3

96

Q92570
ALAGTHHHHHHHHHH

POU4F2

166

Q12837
HHHHHHHHHHHHQPH

POU4F2

171

Q12837
RRHHHHHQHHHQHHH

NCAN

1281

O14594
PHHHHHHHHHHHHHH

SKIDA1

336

Q1XH10
HHHHHHHHHHHRAQP

SKIDA1

341

Q1XH10
HHLSHHHCHHRHHHH

SIAH3

66

Q8IW03
HHCHHRHHHHLRHHA

SIAH3

71

Q8IW03
YGSSHHHHHHHHHHH

SORBS2

636

O94875
HHHHHHHHHHRHLIS

SORBS2

641

O94875
HHHHDYHHILHHHHH

SLC39A6

556

Q13433
GHHHHHHHHHHHTSQ

ZIC3

86

O60481
QQHGHHFQHHHHHHH

RNF111

506

Q6ZNA4
SHHHHHHHHHHRGGE

SYNGAP1

956

Q96PV0
GHAGHHHHHHHHHHH

YY1

66

P25490
GPQHHHHHHHHHHHH

USP34

746

Q70CQ2
HHHHHHHHHHDGHMV

USP34

751

Q70CQ2