Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionWnt receptor activity

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

1.03e-1117646GO:0042813
GeneOntologyMolecularFunctionRNA-DNA hybrid ribonuclease activity

ERVK-6 ERVK-8 ERVK-7 ERVK-10 ERVK-11

1.31e-1011645GO:0004523
GeneOntologyMolecularFunctionRNA-directed DNA polymerase activity

ERVK-6 ERVK-8 ERVK-7 ERVK-10 ERVK-11

5.65e-1014645GO:0003964
GeneOntologyMolecularFunctionWnt-protein binding

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

1.07e-0934646GO:0017147
GeneOntologyMolecularFunctionRNA stem-loop binding

ERVK-6 ERVK-8 ERVK-7 ERVK-10 ERVK-11

5.64e-0921645GO:0035613
GeneOntologyMolecularFunctionRNA endonuclease activity, producing 5'-phosphomonoesters

ERVK-6 ERVK-8 ERVK-7 ERVK-10 ERVK-11

1.16e-0737645GO:0016891
GeneOntologyMolecularFunctionPDZ domain binding

FZD1 FZD4 FZD7 FZD8 CLCN3 GRIA1 FZD2

1.32e-07123647GO:0030165
GeneOntologyMolecularFunctionDNA polymerase activity

ERVK-6 ERVK-8 ERVK-7 ERVK-10 ERVK-11

1.33e-0738645GO:0034061
GeneOntologyMolecularFunctionglutamate-gated receptor activity

GRIA1 GRIK3 GRIN2A GRIN2B

2.21e-0717644GO:0004970
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

ERVK-6 ERVK-8 ERVK-7 ERVK-10 ERVK-11

3.57e-0746645GO:0016893
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

GRIA1 GRIK3 GRIN2A GRIN2B

9.72e-0724644GO:0099507
GeneOntologyMolecularFunctionglutamate receptor activity

GRIA1 GRIK3 GRIN2A GRIN2B

1.59e-0627644GO:0008066
GeneOntologyMolecularFunctionglutamate-gated calcium ion channel activity

GRIA1 GRIN2A GRIN2B

1.74e-068643GO:0022849
GeneOntologyMolecularFunctionRNA endonuclease activity

ERVK-6 ERVK-8 ERVK-7 ERVK-10 ERVK-11

5.42e-0679645GO:0004521
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-6 ERVK-8 ERVK-7 ERVK-10

5.85e-0637644GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-6 ERVK-8 ERVK-7 ERVK-10

6.53e-0638644GO:0070001
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC9A5 KCNQ5 SLC28A2 GRIA1 GRIK3 GRIN2A GRIN2B SLC5A8 SLC9C2

1.65e-05465649GO:0046873
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLCO1B7 SLC44A1 SLC9A5 CLCN3 KCNQ5 SLC28A2 GRIA1 GRIK3 GRIN2A GRIN2B SLC5A8 SLC9C2 SLC14A2 NDUFC1

1.74e-0511806414GO:0022857
GeneOntologyMolecularFunctionamyloid-beta binding

FZD4 FZD5 GRIA1 GRIN2A GRIN2B

1.89e-05102645GO:0001540
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC9A5 CLCN3 KCNQ5 SLC28A2 GRIA1 GRIK3 GRIN2A GRIN2B SLC5A8 SLC9C2 NDUFC1

2.60e-057586411GO:0015318
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC9A5 KCNQ5 SLC28A2 GRIA1 GRIK3 GRIN2A GRIN2B SLC5A8 SLC9C2 NDUFC1

2.85e-056276410GO:0022890
GeneOntologyMolecularFunctioncysteine-S-conjugate beta-lyase activity

KYAT3 KYAT1

3.03e-053642GO:0047804
GeneOntologyMolecularFunctionglycerol kinase activity

GK GK2

3.03e-053642GO:0004370
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

GRIA1 GRIK3 GRIN2A GRIN2B

3.34e-0557644GO:1904315
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC9A5 CLCN3 KCNQ5 SLC28A2 GRIA1 GRIK3 GRIN2A GRIN2B SLC5A8 SLC9C2 NDUFC1

3.93e-057936411GO:0015075
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

GRIA1 GRIK3 GRIN2A GRIN2B

4.09e-0560644GO:0099529
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLCO1B7 SLC44A1 SLC9A5 CLCN3 SLC28A2 SLC5A8 SLC9C2

4.42e-05296647GO:0015291
GeneOntologyMolecularFunctiontransporter activity

SLCO1B7 SLC44A1 SLC9A5 CLCN3 KCNQ5 SLC28A2 GRIA1 GRIK3 GRIN2A GRIN2B SLC5A8 SLC9C2 SLC14A2 NDUFC1

4.61e-0512896414GO:0005215
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC9A5 KCNQ5 SLC28A2 GRIA1 GRIK3 GRIN2A GRIN2B SLC5A8 SLC9C2 NDUFC1

4.63e-056646410GO:0008324
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLCO1B7 GRIA1 GRIK3 GRIN2A GRIN2B SLC5A8

5.25e-05207646GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLCO1B7 GRIA1 GRIK3 GRIN2A GRIN2B SLC5A8

5.39e-05208646GO:0005342
GeneOntologyMolecularFunctiontransmitter-gated channel activity

GRIA1 GRIK3 GRIN2A GRIN2B

5.61e-0565644GO:0022835
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity

GRIA1 GRIK3 GRIN2A GRIN2B

5.61e-0565644GO:0022824
GeneOntologyMolecularFunctionkynurenine-oxoglutarate transaminase activity

KYAT3 KYAT1

6.04e-054642GO:0016212
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration

GRIA1 GRIN2B

6.04e-054642GO:0099583
GeneOntologyMolecularFunctionRNA nuclease activity

ERVK-6 ERVK-8 ERVK-7 ERVK-10 ERVK-11

7.52e-05136645GO:0004540
GeneOntologyMolecularFunctionendonuclease activity

ERVK-6 ERVK-8 ERVK-7 ERVK-10 ERVK-11

7.52e-05136645GO:0004519
GeneOntologyMolecularFunctionpostsynaptic neurotransmitter receptor activity

GRIA1 GRIK3 GRIN2A GRIN2B

9.83e-0575644GO:0098960
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

GRIA1 GRIK3 GRIN2A GRIN2B

1.09e-0477644GO:0005230
GeneOntologyMolecularFunctionnucleotidyltransferase activity

ERVK-6 ERVK-8 ERVK-7 ERVK-10 ERVK-11

1.27e-04152645GO:0016779
GeneOntologyMolecularFunctionligand-gated calcium channel activity

GRIA1 GRIN2A GRIN2B

1.32e-0431643GO:0099604
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLCO1B7 SLC44A1 SLC9A5 CLCN3 SLC28A2 SLC5A8 SLC9C2 NDUFC1

1.37e-04477648GO:0022804
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

JAK2 ERVK-6 ERBB4 GK GK2 ERVK-8 MAP3K11 ERVK-7 ERVK-10 ERVK-11 RSKR

1.75e-049386411GO:0016772
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

ERVK-6 ERVK-8 ERVK-7 ERVK-10 ERVK-11 DNMT3A

1.91e-04262646GO:0140097
GeneOntologyMolecularFunctionextracellularly glutamate-gated ion channel activity

GRIN2A GRIN2B

2.10e-047642GO:0005234
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC9A5 SLC28A2 GRIK3 SLC5A8 SLC9C2

2.20e-04171645GO:0015081
GeneOntologyMolecularFunctionNMDA glutamate receptor activity

GRIN2A GRIN2B

2.80e-048642GO:0004972
GeneOntologyMolecularFunctionneurotransmitter receptor activity

GRIA1 GRIK3 GRIN2A GRIN2B

2.99e-04100644GO:0030594
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLCO1B7 GRIA1 GRIK3 GRIN2A GRIN2B SLC5A8

3.48e-04293646GO:0008514
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

GRIA1 GRIK3 GRIN2A GRIN2B

3.60e-04105644GO:0015171
GeneOntologyMolecularFunctionendopeptidase activity

ERVK-6 ERVK-8 CTRB2 ERVK-7 ERVK-10 CTRB1 PRSS46P

4.41e-04430647GO:0004175
GeneOntologyMolecularFunctionzinc ion binding

ADH5 ERVK-6 CD4 ERVK-8 ERVK-7 GRIN2A GRIN2B ERVK-10 HERC2 ERVK-11

5.05e-048916410GO:0008270
GeneOntologyMolecularFunctiongated channel activity

CLCN3 KCNQ5 GRIA1 GRIK3 GRIN2A GRIN2B

6.94e-04334646GO:0022836
GeneOntologyMolecularFunctionubiquitin protein ligase binding

FZD4 FZD8 FZD5 SPART SCAMP3 HERC2

7.27e-04337646GO:0031625
GeneOntologyMolecularFunctionnuclease activity

ERVK-6 ERVK-8 ERVK-7 ERVK-10 ERVK-11

8.68e-04231645GO:0004518
GeneOntologyMolecularFunctionpotassium:proton antiporter activity

SLC9A5 SLC9C2

8.98e-0414642GO:0015386
GeneOntologyMolecularFunctionglutamate binding

GRIN2A GRIN2B

8.98e-0414642GO:0016595
GeneOntologyMolecularFunctionubiquitin-like protein ligase binding

FZD4 FZD8 FZD5 SPART SCAMP3 HERC2

9.95e-04358646GO:0044389
GeneOntologyMolecularFunctionantiporter activity

SLC44A1 SLC9A5 CLCN3 SLC9C2

1.01e-03138644GO:0015297
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

GRIA1 GRIK3 GRIN2A GRIN2B

1.06e-03140644GO:0099094
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

FZD1 FZD4 FZD7 FZD8 ERBB4 CD4 FZD5 GRIA1 GRIK3 GRIN2A GRIN2B FZD2

1.09e-0313536412GO:0004888
GeneOntologyMolecularFunctionprotein homodimerization activity

FZD1 FZD4 ERVK-6 ERBB4 CD4 TENM3 MAP3K11 KYAT3 KYAT1

1.11e-03815649GO:0042803
GeneOntologyMolecularFunctionsodium:proton antiporter activity

SLC9A5 SLC9C2

1.18e-0316642GO:0015385
GeneOntologyMolecularFunctioncarbon-sulfur lyase activity

KYAT3 KYAT1

1.18e-0316642GO:0016846
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

CLCN3 KCNQ5 GRIA1 GRIK3 GRIN2A GRIN2B SLC5A8

1.44e-03526647GO:0022803
GeneOntologyMolecularFunctionorganic hydroxy compound transmembrane transporter activity

SLCO1B7 SLC44A1 SLC5A8

1.47e-0370643GO:1901618
GeneOntologyMolecularFunctionsolute:potassium antiporter activity

SLC9A5 SLC9C2

1.67e-0319642GO:0022821
GeneOntologyMolecularFunctionprotein domain specific binding

FZD1 FZD4 FZD7 JAK2 FZD8 CLCN3 GRIA1 FKBP8 FZD2

1.81e-03875649GO:0019904
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

SLC9A5 KCNQ5 GRIK3 SLC9C2

2.03e-03167644GO:0015079
GeneOntologyMolecularFunctionglutamate receptor binding

GRIA1 GRIN2A GRIN2B

2.24e-0381643GO:0035254
GeneOntologyMolecularFunctionamide binding

FZD4 FZD5 GRIA1 GRIN2A GRIN2B

2.70e-03299645GO:0033218
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

CLCN3 KCNQ5 GRIN2A GRIN2B

2.77e-03182644GO:0005244
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC9A5 SLC28A2 SLC5A8 SLC9C2 NDUFC1

2.78e-03301645GO:0022853
GeneOntologyMolecularFunctionvoltage-gated channel activity

CLCN3 KCNQ5 GRIN2A GRIN2B

2.88e-03184644GO:0022832
GeneOntologyMolecularFunctiontransaminase activity

KYAT3 KYAT1

3.13e-0326642GO:0008483
GeneOntologyMolecularFunctionscaffold protein binding

GRIA1 GRIN2A GRIN2B

3.32e-0393643GO:0097110
GeneOntologyMolecularFunctionmetal cation:proton antiporter activity

SLC9A5 SLC9C2

3.37e-0327642GO:0051139
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

GRIA1 GRIK3 GRIN2A GRIN2B

3.42e-03193644GO:0015276
GeneOntologyMolecularFunctionmonoatomic ion channel activity

CLCN3 KCNQ5 GRIA1 GRIK3 GRIN2A GRIN2B

3.47e-03459646GO:0005216
GeneOntologyMolecularFunctionpeptide binding

FZD4 FZD5 GRIA1 GRIN2A GRIN2B

3.51e-03318645GO:0042277
GeneOntologyMolecularFunctiontransferase activity, transferring nitrogenous groups

KYAT3 KYAT1

3.62e-0328642GO:0016769
GeneOntologyMolecularFunctionligand-gated channel activity

GRIA1 GRIK3 GRIN2A GRIN2B

3.68e-03197644GO:0022834
GeneOntologyMolecularFunctiontransition metal ion binding

ADH5 ERVK-6 CD4 ERVK-8 ERVK-7 GRIN2A GRIN2B ERVK-10 HERC2 ERVK-11

4.33e-0311896410GO:0046914
GeneOntologyMolecularFunctionG protein-coupled receptor binding

FZD1 FZD7 JAK2 GRIA1 GRIN2B

4.49e-03337645GO:0001664
GeneOntologyMolecularFunctionprotein dimerization activity

FZD1 FZD4 ERVK-6 ERBB4 CD4 TENM3 MAP3K11 KYAT3 FZD2 KYAT1

4.76e-0312056410GO:0046983
GeneOntologyMolecularFunctionpeptidase activity

ERVK-6 ERVK-8 CTRB2 ERVK-7 ERVK-10 CTRB1 PRSS46P

4.83e-03654647GO:0008233
GeneOntologyMolecularFunctionmonoatomic cation channel activity

KCNQ5 GRIA1 GRIK3 GRIN2A GRIN2B

4.84e-03343645GO:0005261
GeneOntologyMolecularFunctionimmunoglobulin binding

CD4 GRIA1

5.94e-0336642GO:0019865
GeneOntologyBiologicalProcessDNA integration

ERVK-6 ERVK-8 ERVK-7 ERVK-10 ERVK-11

2.86e-1013635GO:0015074
GeneOntologyBiologicalProcessnon-canonical Wnt signaling pathway

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

1.27e-0777636GO:0035567
GeneOntologyBiologicalProcessDNA synthesis involved in DNA repair

ERVK-6 ERVK-8 ERVK-7 ERVK-10 ERVK-11

3.50e-0748635GO:0000731
GeneOntologyBiologicalProcessionotropic glutamate receptor signaling pathway

GRIA1 GRIK3 GRIN2A GRIN2B

1.32e-0627634GO:0035235
GeneOntologyBiologicalProcessRNA-templated DNA biosynthetic process

ERVK-6 ERVK-8 ERVK-7 ERVK-10 ERVK-11

5.47e-0683635GO:0006278
GeneOntologyBiologicalProcessligand-gated ion channel signaling pathway

GRIA1 GRIK3 GRIN2A GRIN2B

6.65e-0640634GO:1990806
GeneOntologyBiologicalProcesspositive regulation of JUN kinase activity

FZD4 FZD8 FZD5 MAP3K11

1.51e-0549634GO:0043507
GeneOntologyBiologicalProcessglycerol-3-phosphate biosynthetic process

GK GK2

2.75e-053632GO:0046167
GeneOntologyBiologicalProcessglutamate receptor signaling pathway

GRIA1 GRIK3 GRIN2A GRIN2B

3.17e-0559634GO:0007215
GeneOntologyBiologicalProcessglycerol metabolic process

GK GK2 COQ2

4.01e-0522633GO:0006071
GeneOntologyBiologicalProcesssynaptic transmission, glutamatergic

CLCN3 GRIA1 GRIK3 GRIN2A GRIN2B

5.19e-05132635GO:0035249
GeneOntologyBiologicalProcessregulation of JUN kinase activity

FZD4 FZD8 FZD5 MAP3K11

5.24e-0567634GO:0043506
GeneOntologyBiologicalProcessL-kynurenine catabolic process

KYAT3 KYAT1

5.49e-054632GO:0097053
GeneOntologyBiologicalProcessalditol metabolic process

GK GK2 COQ2

6.72e-0526633GO:0019400
GeneOntologyBiologicalProcessregulation of presynaptic membrane potential

GRIA1 GRIK3 GRIN2B

1.26e-0432633GO:0099505
GeneOntologyBiologicalProcessmuscular septum morphogenesis

FZD1 FZD2

1.37e-046632GO:0003150
GeneOntologyBiologicalProcessglycerol catabolic process

GK GK2

1.37e-046632GO:0019563
GeneOntologyBiologicalProcessWnt signaling pathway, calcium modulating pathway

FZD4 FZD2

1.91e-047632GO:0007223
GeneOntologyBiologicalProcessL-kynurenine metabolic process

KYAT3 KYAT1

1.91e-047632GO:0097052
GeneOntologyBiologicalProcessalditol catabolic process

GK GK2

1.91e-047632GO:0019405
GeneOntologyBiologicalProcessDNA-templated DNA replication

ERVK-6 ERVK-8 ERVK-7 ERVK-10 ERVK-11

2.12e-04178635GO:0006261
GeneOntologyBiologicalProcesssynapse organization

FZD1 ERBB4 TENM3 FZD5 GRIA1 GRIN2A GRIN2B MFN1 GNPAT

2.22e-04685639GO:0050808
GeneOntologyBiologicalProcesspositive regulation of kinase activity

FZD4 JAK2 FZD8 ERBB4 CD4 FZD5 MAP3K11

2.29e-04405637GO:0033674
GeneOntologyBiologicalProcesspositive regulation of catalytic activity

FZD4 JAK2 FZD8 ERBB4 CD4 FZD5 APAF1 MAP3K11 GRIN2A GRIN2B SNX13

2.54e-0410286311GO:0043085
GeneOntologyBiologicalProcesspositive regulation of molecular function

FZD1 FZD4 JAK2 FZD8 ERBB4 CD4 FZD5 APAF1 MAP3K11 GRIN2A GRIN2B FZD2 SNX13

3.24e-0414306313GO:0044093
GeneOntologyBiologicalProcessestablishment of planar polarity

FZD1 ERBB4 FZD2

3.29e-0444633GO:0001736
GeneOntologyBiologicalProcesspositive regulation of MAPK cascade

FZD4 FZD7 JAK2 FZD8 ERBB4 CD4 FZD5 MAP3K11

3.33e-04571638GO:0043410
GeneOntologyBiologicalProcessestablishment of tissue polarity

FZD1 ERBB4 FZD2

3.52e-0445633GO:0007164
GeneOntologyBiologicalProcessalcohol catabolic process

ADH5 GK GK2

4.00e-0447633GO:0046164
GeneOntologyBiologicalProcessmembranous septum morphogenesis

FZD1 FZD2

4.07e-0410632GO:0003149
GeneOntologyBiologicalProcesspositive regulation of inhibitory postsynaptic potential

GRIN2A GRIN2B

4.07e-0410632GO:0097151
GeneOntologyBiologicalProcesshard palate development

FZD1 FZD2

4.07e-0410632GO:0060022
GeneOntologyBiologicalProcessglycerol-3-phosphate metabolic process

GK GK2

4.07e-0410632GO:0006072
GeneOntologyBiologicalProcessresponse to granulocyte macrophage colony-stimulating factor

JAK2 CD4

4.96e-0411632GO:0097012
GeneOntologyBiologicalProcesskynurenine metabolic process

KYAT3 KYAT1

4.96e-0411632GO:0070189
GeneOntologyBiologicalProcessDNA biosynthetic process

ERVK-6 ERVK-8 ERVK-7 ERVK-10 ERVK-11

5.38e-04218635GO:0071897
GeneOntologyBiologicalProcesspositive regulation of phosphorylation

FZD1 FZD4 FZD7 JAK2 FZD8 ERBB4 CD4 FZD5 MAP3K11

5.73e-04780639GO:0042327
GeneOntologyBiologicalProcessalditol phosphate metabolic process

GK GK2

5.94e-0412632GO:0052646
GeneOntologyBiologicalProcessmodulation of inhibitory postsynaptic potential

GRIN2A GRIN2B

5.94e-0412632GO:0098828
GeneOntologyBiologicalProcesspolyol catabolic process

GK GK2

5.94e-0412632GO:0046174
GeneOntologyBiologicalProcesscanonical Wnt signaling pathway

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

6.29e-04344636GO:0060070
GeneOntologyBiologicalProcessWnt signaling pathway, planar cell polarity pathway

FZD1 FZD7 FZD2

6.36e-0455633GO:0060071
GeneOntologyBiologicalProcesspositive regulation of MAP kinase activity

FZD4 FZD8 FZD5 MAP3K11

6.54e-04129634GO:0043406
GeneOntologyBiologicalProcesspositive regulation of protein kinase activity

FZD4 JAK2 FZD8 CD4 FZD5 MAP3K11

6.89e-04350636GO:0045860
GeneOntologyBiologicalProcessregulation of BMP signaling pathway

FZD1 UBE2O SPART FKBP8

6.93e-04131634GO:0030510
GeneOntologyBiologicalProcessregulation of postsynaptic cytosolic calcium ion concentration

GRIA1 GRIN2B

7.01e-0413632GO:0099566
GeneOntologyBiologicalProcesspositive regulation of transferase activity

FZD4 JAK2 FZD8 ERBB4 CD4 FZD5 MAP3K11

7.18e-04490637GO:0051347
GeneOntologyBiologicalProcessorganophosphate biosynthetic process

ERBB4 SLC44A1 GK GK2 CWH43 SLC5A8 NDUFC1 GNPAT

7.37e-04644638GO:0090407
GeneOntologyBiologicalProcessresponse to amine

JAK2 GRIA1 GRIN2A

7.43e-0458633GO:0014075
GeneOntologyBiologicalProcessregulation of MAPK cascade

FZD4 FZD7 JAK2 FZD8 ERBB4 CD4 FZD5 MAP3K11 GRIN2B

7.84e-04815639GO:0043408
GeneOntologyBiologicalProcessregulation of establishment of planar polarity involved in neural tube closure

FZD1 FZD2

9.40e-0415632GO:0090178
GeneOntologyBiologicalProcessexcitatory chemical synaptic transmission

GRIN2A GRIN2B

1.07e-0316632GO:0098976
GeneOntologyBiologicalProcessestablishment of planar polarity involved in neural tube closure

FZD1 FZD2

1.07e-0316632GO:0090177
GeneOntologyBiologicalProcessregulation of phosphorylation

FZD1 FZD4 FZD7 JAK2 FZD8 ERBB4 CD4 FZD5 MAP3K11 FKBP8 KIRREL2

1.11e-0312266311GO:0042325
GeneOntologyBiologicalProcessbrain development

FZD1 FZD4 ERBB4 CWH43 APAF1 GRIA1 GRIN2A GRIN2B GNPAT

1.14e-03859639GO:0007420
GeneOntologyBiologicalProcesspositive regulation of cysteine-type endopeptidase activity

JAK2 APAF1 GRIN2A GRIN2B

1.20e-03152634GO:2001056
GeneOntologyBiologicalProcesspositive regulation of phosphate metabolic process

FZD1 FZD4 FZD7 JAK2 FZD8 ERBB4 CD4 FZD5 MAP3K11

1.33e-03879639GO:0045937
GeneOntologyBiologicalProcesspositive regulation of phosphorus metabolic process

FZD1 FZD4 FZD7 JAK2 FZD8 ERBB4 CD4 FZD5 MAP3K11

1.33e-03879639GO:0010562
GeneOntologyBiologicalProcessestablishment of planar polarity of embryonic epithelium

FZD1 FZD2

1.36e-0318632GO:0042249
GeneOntologyBiologicalProcessmorphogenesis of a polarized epithelium

FZD1 ERBB4 FZD2

1.45e-0373633GO:0001738
GeneOntologyBiologicalProcessorganic hydroxy compound catabolic process

ADH5 GK GK2

1.45e-0373633GO:1901616
GeneOntologyBiologicalProcessresponse to ethanol

GK GRIN2A GRIN2B DNMT3A

1.49e-03161634GO:0045471
GeneOntologyBiologicalProcessregulation of establishment of planar polarity

FZD1 FZD2

1.52e-0319632GO:0090175
GeneOntologyBiologicalProcesspositive regulation of protein phosphorylation

FZD1 FZD4 JAK2 FZD8 ERBB4 CD4 FZD5 MAP3K11

1.56e-03724638GO:0001934
GeneOntologyBiologicalProcesshead development

FZD1 FZD4 ERBB4 CWH43 APAF1 GRIA1 GRIN2A GRIN2B GNPAT

1.81e-03919639GO:0060322
GeneOntologyCellularComponentvesicle membrane

FZD4 FZD7 CHMP7 CD4 SLC9A5 CLCN3 PLA1A FZD5 SLC28A2 GRIA1 TSPAN14 SLC35G2 SCAMP3 GRIN2A GRIN2B FZD2 SNX13

2.42e-0713256317GO:0012506
GeneOntologyCellularComponentcytoplasmic vesicle membrane

FZD4 FZD7 CHMP7 CD4 SLC9A5 CLCN3 PLA1A FZD5 GRIA1 TSPAN14 SLC35G2 SCAMP3 GRIN2A GRIN2B FZD2 SNX13

1.11e-0613076316GO:0030659
GeneOntologyCellularComponentionotropic glutamate receptor complex

GRIA1 GRIK3 GRIN2A GRIN2B

1.02e-0545634GO:0008328
GeneOntologyCellularComponentneurotransmitter receptor complex

GRIA1 GRIK3 GRIN2A GRIN2B

1.55e-0550634GO:0098878
GeneOntologyCellularComponentpresynaptic membrane

ERBB4 KCNQ5 TENM3 GRIA1 GRIK3 GRIN2A GRIN2B

1.95e-05277637GO:0042734
GeneOntologyCellularComponentrecycling endosome membrane

FZD7 SLC9A5 CLCN3 GRIA1 SCAMP3

2.21e-05112635GO:0055038
GeneOntologyCellularComponentsynaptic membrane

ERBB4 SLC9A5 CLCN3 KCNQ5 TENM3 GRIA1 GRIK3 GRIN2A GRIN2B

5.94e-05583639GO:0097060
GeneOntologyCellularComponentclathrin-coated endocytic vesicle membrane

FZD4 CD4 FZD5 FZD2

9.50e-0579634GO:0030669
GeneOntologyCellularComponentpostsynaptic density membrane

ERBB4 GRIA1 GRIK3 GRIN2A GRIN2B

1.11e-04157635GO:0098839
GeneOntologyCellularComponentglutamatergic synapse

FZD4 JAK2 ERBB4 CLCN3 TENM3 FZD5 GRIA1 GRIK3 GRIN2A GRIN2B

1.54e-048176310GO:0098978
GeneOntologyCellularComponentpostsynaptic membrane

ERBB4 SLC9A5 CLCN3 GRIA1 GRIK3 GRIN2A GRIN2B

2.12e-04405637GO:0045211
GeneOntologyCellularComponentclathrin-coated endocytic vesicle

FZD4 CD4 FZD5 FZD2

2.46e-04101634GO:0045334
GeneOntologyCellularComponentmitochondrial membrane

SLC44A1 GK GK2 SPART FKBP8 HERC2 COQ2 NDUFC1 MFN1 GNPAT

2.46e-048666310GO:0031966
GeneOntologyCellularComponentNMDA selective glutamate receptor complex

GRIN2A GRIN2B

3.17e-049632GO:0017146
GeneOntologyCellularComponentpostsynaptic specialization membrane

ERBB4 GRIA1 GRIK3 GRIN2A GRIN2B

3.50e-04201635GO:0099634
GeneOntologyCellularComponentmitochondrial envelope

SLC44A1 GK GK2 SPART FKBP8 HERC2 COQ2 NDUFC1 MFN1 GNPAT

3.72e-049126310GO:0005740
GeneOntologyCellularComponentaxon terminus

CLCN3 KCNQ5 GRIK3 GRIN2A GRIN2B

4.27e-04210635GO:0043679
GeneOntologyCellularComponentendosome membrane

FZD7 CHMP7 SLC9A5 CLCN3 FZD5 GRIA1 SCAMP3 SNX13

4.34e-04602638GO:0010008
GeneOntologyCellularComponentpostsynaptic density, intracellular component

GRIA1 GRIN2A GRIN2B

4.35e-0449633GO:0099092
GeneOntologyCellularComponentendocytic vesicle membrane

FZD4 CD4 FZD5 GRIA1 FZD2

4.46e-04212635GO:0030666
GeneOntologyCellularComponentcoated vesicle membrane

FZD4 CD4 FZD5 GRIA1 FZD2

4.76e-04215635GO:0030662
GeneOntologyCellularComponentrecycling endosome

FZD7 SLC9A5 CLCN3 GRIA1 SCAMP3

5.50e-04222635GO:0055037
GeneOntologyCellularComponentplasma membrane signaling receptor complex

JAK2 CD4 GRIA1 GRIK3 GRIN2A GRIN2B

6.42e-04350636GO:0098802
GeneOntologyCellularComponentdendrite membrane

SLC9A5 GRIA1 GRIN2A

6.45e-0456633GO:0032590
GeneOntologyCellularComponentpostsynaptic specialization, intracellular component

GRIA1 GRIN2A GRIN2B

6.45e-0456633GO:0099091
GeneOntologyCellularComponentendosome

FZD7 JAK2 CHMP7 CD4 SLC9A5 CLCN3 FZD5 GRIA1 SCAMP3 GRIN2B SNX13

6.63e-0411676311GO:0005768
GeneOntologyCellularComponentneuron projection terminus

CLCN3 KCNQ5 GRIK3 GRIN2A GRIN2B

6.85e-04233635GO:0044306
GeneOntologyCellularComponentcoated vesicle

FZD4 CD4 FZD5 SLC28A2 GRIA1 FZD2

7.44e-04360636GO:0030135
GeneOntologyCellularComponentmitochondrial outer membrane

SLC44A1 GK GK2 SPART MFN1

7.97e-04241635GO:0005741
GeneOntologyCellularComponentclathrin-coated vesicle membrane

FZD4 CD4 FZD5 FZD2

1.01e-03147634GO:0030665
GeneOntologyCellularComponentendocytic vesicle

FZD4 CD4 CLCN3 FZD5 GRIA1 FZD2

1.04e-03384636GO:0030139
GeneOntologyCellularComponentorganelle envelope

CHMP7 SLC44A1 GK GK2 SPART LMNB2 FKBP8 HERC2 COQ2 NDUFC1 MFN1 GNPAT

1.06e-0314356312GO:0031967
GeneOntologyCellularComponentpresynapse

ERBB4 CLCN3 KCNQ5 TENM3 GRIA1 SLC35G2 GRIK3 GRIN2A GRIN2B

1.28e-03886639GO:0098793
GeneOntologyCellularComponentdendritic spine membrane

SLC9A5 GRIA1

1.33e-0318632GO:0032591
GeneOntologyCellularComponentaxon

CLCN3 KCNQ5 TENM3 FZD5 GRIA1 GRIK3 GRIN2A GRIN2B NRSN1

1.34e-03891639GO:0030424
GeneOntologyCellularComponentorganelle outer membrane

SLC44A1 GK GK2 SPART MFN1

1.53e-03279635GO:0031968
GeneOntologyCellularComponentouter membrane

SLC44A1 GK GK2 SPART MFN1

1.58e-03281635GO:0019867
GeneOntologyCellularComponentpresynaptic active zone membrane

TENM3 GRIA1 GRIN2B

1.69e-0378633GO:0048787
GeneOntologyCellularComponentreceptor complex

JAK2 ERBB4 CD4 GRIA1 GRIK3 GRIN2A GRIN2B

1.78e-03581637GO:0043235
GeneOntologyCellularComponentcell projection membrane

SLC9A5 CLCN3 SLC28A2 GRIA1 GRIN2A SLC5A8

1.87e-03431636GO:0031253
GeneOntologyCellularComponentneuron projection membrane

SLC9A5 GRIA1 GRIN2A

1.95e-0382633GO:0032589
GeneOntologyCellularComponentdistal axon

CLCN3 KCNQ5 GRIK3 GRIN2A GRIN2B NRSN1

1.96e-03435636GO:0150034
GeneOntologyCellularComponentsynaptic vesicle

CLCN3 GRIA1 SLC35G2 GRIN2A GRIN2B

2.10e-03300635GO:0008021
GeneOntologyCellularComponentplasma membrane protein complex

JAK2 FZD8 CD4 KCNQ5 GRIA1 GRIK3 GRIN2A GRIN2B

2.38e-03785638GO:0098797
GeneOntologyCellularComponentexocytic vesicle

CLCN3 GRIA1 SLC35G2 GRIN2A GRIN2B

2.77e-03320635GO:0070382
GeneOntologyCellularComponentterminal bouton

GRIK3 GRIN2A GRIN2B

3.05e-0396633GO:0043195
GeneOntologyCellularComponentleading edge membrane

SLC9A5 CLCN3 GRIA1 GRIN2A

3.71e-03210634GO:0031256
GeneOntologyCellularComponentearly endosome membrane

CLCN3 FZD5 GRIA1 SNX13

3.84e-03212634GO:0031901
GeneOntologyCellularComponentinhibitory synapse

ERBB4 CLCN3

3.93e-0331632GO:0060077
GeneOntologyCellularComponentdendrite

FZD4 ERBB4 SLC9A5 FZD5 GRIA1 GRIK3 GRIN2A GRIN2B

4.10e-03858638GO:0030425
GeneOntologyCellularComponentexcitatory synapse

GRIA1 GRIN2A GRIN2B

4.14e-03107633GO:0060076
GeneOntologyCellularComponentdendritic tree

FZD4 ERBB4 SLC9A5 FZD5 GRIA1 GRIK3 GRIN2A GRIN2B

4.15e-03860638GO:0097447
GeneOntologyCellularComponenttransport vesicle

CLCN3 GRIA1 SLC35G2 GRIN2A GRIN2B NRSN1

4.67e-03519636GO:0030133
GeneOntologyCellularComponentmembrane protein complex

JAK2 FZD8 CHMP7 CD4 KCNQ5 GRIA1 GRIK3 GRIN2A GRIN2B NDUFC1 MFN1

4.79e-0314986311GO:0098796
GeneOntologyCellularComponenttransmembrane transporter complex

KCNQ5 GRIA1 GRIK3 GRIN2A GRIN2B NDUFC1

4.85e-03523636GO:1902495
GeneOntologyCellularComponentmonoatomic ion channel complex

KCNQ5 GRIA1 GRIK3 GRIN2A GRIN2B

5.61e-03378635GO:0034702
GeneOntologyCellularComponentclathrin-coated vesicle

FZD4 CD4 FZD5 FZD2

5.69e-03237634GO:0030136
GeneOntologyCellularComponentcell surface

FZD1 FZD4 CD4 CLCN3 FZD5 GRIA1 TSPAN14 GRIN2A GRIN2B

5.84e-031111639GO:0009986
GeneOntologyCellularComponentdendritic spine

SLC9A5 GRIA1 GRIN2A GRIN2B

6.12e-03242634GO:0043197
GeneOntologyCellularComponenttransporter complex

KCNQ5 GRIA1 GRIK3 GRIN2A GRIN2B NDUFC1

6.17e-03550636GO:1990351
GeneOntologyCellularComponentneuron spine

SLC9A5 GRIA1 GRIN2A GRIN2B

6.57e-03247634GO:0044309
GeneOntologyCellularComponentparallel fiber to Purkinje cell synapse

GRIN2A GRIN2B

7.46e-0343632GO:0098688
GeneOntologyCellularComponentanchoring junction

FZD1 FZD4 JAK2 SLC9A5 FZD5 GRIA1 KIRREL2 FZD2

8.73e-03976638GO:0070161
GeneOntologyCellularComponentpresynaptic active zone

TENM3 GRIA1 GRIN2B

8.88e-03141633GO:0048786
GeneOntologyCellularComponentsomatodendritic compartment

FZD4 ERBB4 SLC9A5 FZD5 GRIA1 GRIK3 GRIN2A GRIN2B NRSN1

1.09e-021228639GO:0036477
GeneOntologyCellularComponentpostsynapse

JAK2 ERBB4 SLC9A5 CLCN3 GRIA1 GRIK3 GRIN2A GRIN2B

1.11e-021018638GO:0098794
GeneOntologyCellularComponentpostsynaptic density

ERBB4 GRIA1 GRIK3 GRIN2A GRIN2B

1.15e-02451635GO:0014069
GeneOntologyCellularComponenttransport vesicle membrane

CLCN3 GRIA1 SLC35G2 GRIN2B

1.18e-02293634GO:0030658
GeneOntologyCellularComponentsecretory vesicle

FZD8 CLCN3 PLA1A APAF1 GRIA1 TSPAN14 SLC35G2 GRIN2A GRIN2B

1.20e-021246639GO:0099503
GeneOntologyCellularComponentasymmetric synapse

ERBB4 GRIA1 GRIK3 GRIN2A GRIN2B

1.44e-02477635GO:0032279
GeneOntologyCellularComponentearly endosome

CD4 CLCN3 FZD5 GRIA1 SNX13

1.49e-02481635GO:0005769
DomainFrizzled

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

3.49e-1311596IPR000539
DomainFrizzled

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

3.49e-1311596PF01534
DomainFrizzled

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

3.49e-1311596SM01330
DomainFrizzled/SFRP

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

5.98e-1216596IPR015526
DomainFRI

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

2.87e-1120596SM00063
Domain-

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

4.00e-11215961.10.2000.10
DomainFrizzled_dom

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

9.85e-1124596IPR020067
DomainFZ

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

9.85e-1124596PS50038
DomainFz

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

9.85e-1124596PF01392
DomainGPCR_2-like

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

3.36e-0860596IPR017981
DomainG_PROTEIN_RECEP_F2_4

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

3.71e-0861596PS50261
DomainIontro_rcpt

GRIA1 GRIK3 GRIN2A GRIN2B

2.66e-0718594IPR001320
DomainLig_chan-Glu_bd

GRIA1 GRIK3 GRIN2A GRIN2B

2.66e-0718594PF10613
DomainIono_rcpt_met

GRIA1 GRIK3 GRIN2A GRIN2B

2.66e-0718594IPR001508
DomainGlu/Gly-bd

GRIA1 GRIK3 GRIN2A GRIN2B

2.66e-0718594IPR019594
DomainLig_chan-Glu_bd

GRIA1 GRIK3 GRIN2A GRIN2B

2.66e-0718594SM00918
DomainLig_chan

GRIA1 GRIK3 GRIN2A GRIN2B

2.66e-0718594PF00060
DomainPBPe

GRIA1 GRIK3 GRIN2A GRIN2B

2.66e-0718594SM00079
DomainGPCR_2_secretin-like

FZD1 FZD4 FZD7 FZD8 FZD2

1.27e-0660595IPR000832
DomainANF_lig-bd_rcpt

GRIA1 GRIK3 GRIN2A GRIN2B

5.49e-0637594IPR001828
DomainANF_receptor

GRIA1 GRIK3 GRIN2A GRIN2B

5.49e-0637594PF01094
DomainPeripla_BP_I

GRIA1 GRIK3 GRIN2A GRIN2B

6.80e-0639594IPR028082
DomainNMDAR2_C

GRIN2A GRIN2B

2.94e-053592PF10565
DomainCarb_kinase_FGGY_CS

GK GK2

2.94e-053592IPR018483
DomainNMDAR2_C

GRIN2A GRIN2B

2.94e-053592IPR018884
DomainGlycerol_kin

GK GK2

5.86e-054592IPR005999
DomainFGGY_KINASES_2

GK GK2

9.75e-055592PS00445
DomainFGGY_KINASES_1

GK GK2

9.75e-055592PS00933
DomainCarb_kinase_FGGY_C

GK GK2

9.75e-055592IPR018485
DomainFGGY_C

GK GK2

1.46e-046592PF02782
DomainCarb_kinase_FGGY_N

GK GK2

1.46e-046592IPR018484
DomainCarb_kinase_FGGY

GK GK2

2.04e-047592IPR000577
DomainFGGY_N

GK GK2

2.04e-047592PF00370
DomainCation/H_exchanger_CPA1

SLC9A5 SLC9C2

5.30e-0411592IPR018422
DomainNa_H_Exchanger

SLC9A5 SLC9C2

8.71e-0414592PF00999
DomainEamA_dom

SLC35G2 SLC35F4

8.71e-0414592IPR000620
DomainCation/H_exchanger

SLC9A5 SLC9C2

8.71e-0414592IPR006153
DomainEamA

SLC35G2 SLC35F4

8.71e-0414592PF00892
DomainAminotransferase_I/II

KYAT3 KYAT1

1.29e-0317592IPR004839
DomainAminotran_1_2

KYAT3 KYAT1

1.29e-0317592PF00155
DomainTetraspanin_CS

TSPAN14 TSPAN5

1.98e-0321592IPR018503
DomainTyrKc

JAK2 ERBB4 MAP3K11

2.72e-0388593SM00219
DomainTyr_kinase_cat_dom

JAK2 ERBB4 MAP3K11

2.72e-0388593IPR020635
DomainTM4_1

TSPAN14 TSPAN5

3.04e-0326592PS00421
DomainTRYPSIN_HIS

CTRB2 CTRB1 PRSS46P

4.23e-03103593IPR018114
DomainTetraspanin

TSPAN14 TSPAN5

4.58e-0332592IPR000301
DomainTetraspanin_EC2

TSPAN14 TSPAN5

4.58e-0332592IPR008952
DomainTRYPSIN_HIS

CTRB2 CTRB1 PRSS46P

4.71e-03107593PS00134
DomainTetraspannin

TSPAN14 TSPAN5

4.86e-0333592PF00335
DomainTetraspanin/Peripherin

TSPAN14 TSPAN5

4.86e-0333592IPR018499
Domain-

KYAT3 KYAT1

5.46e-03355923.90.1150.10
DomainPeptidase_S1A

CTRB2 CTRB1 PRSS46P

5.48e-03113593IPR001314
DomainTRYPSIN_DOM

CTRB2 CTRB1 PRSS46P

5.75e-03115593PS50240
DomainPyrdxlP-dep_Trfase_major_sub2

KYAT3 KYAT1

5.77e-0336592IPR015422
DomainTryp_SPc

CTRB2 CTRB1 PRSS46P

6.04e-03117593SM00020
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_SOST_LRP4

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

2.90e-1214476M47834
PathwayKEGG_MEDICUS_REFERENCE_WNT5A_ROR_SIGNALING_PATHWAY

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

7.70e-1216476M47823
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_LGR_RSPO

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

2.59e-1119476M47833
PathwayWP_PHYSICOCHEMICAL_FEATURES_AND_TOXICITYASSOCIATED_PATHWAYS

FZD1 FZD4 FZD7 FZD8 ERBB4 FZD5 GRIA1 FZD2

4.06e-1166478M39642
PathwayPID_WNT_SIGNALING_PATHWAY

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

3.52e-1028476M77
PathwayWP_WNT_SIGNALING_IN_KIDNEY_DISEASE

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

1.78e-0936476M39699
PathwayWP_WNT_SIGNALING_IN_KIDNEY_DISEASE

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

6.33e-0944476MM15878
PathwayKEGG_MEDICUS_VARIANT_LRP6_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

7.29e-0945476M47412
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_PATHWAY

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

8.36e-0946476M47409
PathwayKEGG_BASAL_CELL_CARCINOMA

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

2.53e-0855476M17807
PathwayREACTOME_ASYMMETRIC_LOCALIZATION_OF_PCP_PROTEINS

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

4.31e-0860476MM15150
PathwayREACTOME_ASYMMETRIC_LOCALIZATION_OF_PCP_PROTEINS

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

6.40e-0864476M27396
PathwayREACTOME_PCP_CE_PATHWAY

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

3.54e-0785476MM15041
PathwayWP_POLYCYSTIC_KIDNEY_DISEASE_PATHWAY

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

3.54e-0785476M48315
PathwayWNT_SIGNALING

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

4.66e-0789476M5493
PathwayREACTOME_PCP_CE_PATHWAY

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

5.67e-0792476M27322
PathwayREACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

6.44e-0794476M797
PathwayREACTOME_LONG_TERM_POTENTIATION

ERBB4 GRIA1 GRIN2A GRIN2B

9.17e-0723474M27949
PathwayWP_WNT_SIGNALING_AND_PLURIPOTENCY

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

9.86e-07101476M39387
PathwayKEGG_MELANOGENESIS

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

9.86e-07101476M7761
PathwayWP_WNT_SIGNALING_PATHWAY_AND_PLURIPOTENCY

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

9.86e-07101476MM15829
PathwayWP_WNT_SIGNALING_PATHWAY

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

1.63e-06110476MM15977
PathwayWP_WNT_SIGNALING

FZD1 FZD7 FZD8 FZD5 FZD2

1.71e-0661475MM15893
PathwayREACTOME_SIGNALING_BY_RNF43_MUTANTS

FZD4 FZD8 FZD5

1.92e-068473M27433
PathwayWP_ALZHEIMERS_DISEASE

FZD1 FZD7 FZD8 FZD5 APAF1 GRIN2A GRIN2B FZD2

2.09e-06261478M42565
PathwayWP_ESC_PLURIPOTENCY_PATHWAYS

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

2.22e-06116476MM15863
PathwayWP_EMBRYONIC_STEM_CELL_PLURIPOTENCY_PATHWAYS

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

2.34e-06117476M39530
PathwayWP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

2.46e-06118476M39852
PathwayREACTOME_BETA_CATENIN_INDEPENDENT_WNT_SIGNALING

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

3.13e-06123476MM14988
PathwayREACTOME_BETA_CATENIN_INDEPENDENT_WNT_SIGNALING

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

8.43e-06146476M27288
PathwayKEGG_WNT_SIGNALING_PATHWAY

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

1.02e-05151476M19428
PathwayWP_ALZHEIMERS_DISEASE_AND_MIRNA_EFFECTS

FZD1 FZD7 FZD8 FZD5 APAF1 GRIN2A GRIN2B FZD2

1.08e-05326478M39379
PathwayWP_NCRNAS_INVOLVED_IN_WNT_SIGNALING_IN_HEPATOCELLULAR_CARCINOMA

FZD1 FZD7 FZD8 FZD5 FZD2

1.11e-0589475M39563
PathwayWP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

1.47e-05161476M39770
PathwayWP_LNCRNA_IN_CANONICAL_WNT_SIGNALING_AND_COLORECTAL_CANCER

FZD1 FZD7 FZD8 FZD5 FZD2

1.78e-0598475M39731
PathwayWP_REGULATION_OF_WNT_BCATENIN_SIGNALING_BY_SMALL_MOLECULE_COMPOUNDS

FZD1 FZD7 FZD8

2.29e-0517473M39525
PathwayWP_NRXN1_DELETION_SYNDROME

GRIA1 GRIN2A GRIN2B

2.74e-0518473M48098
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_TRANSPORT_OF_CALCIUM

APAF1 GRIN2A GRIN2B

2.74e-0518473M47761
PathwayKEGG_AMYOTROPHIC_LATERAL_SCLEROSIS_ALS

APAF1 GRIA1 GRIN2A GRIN2B

2.82e-0553474M3812
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_TRANSPORT_OF_CALCIUM

APAF1 GRIN2A GRIN2B

3.24e-0519473M47677
PathwayWP_WNT_SIGNALING_WP428

FZD1 FZD7 FZD8 FZD5 FZD2

3.55e-05113475M39669
PathwayREACTOME_REGULATION_OF_FZD_BY_UBIQUITINATION

FZD4 FZD8 FZD5

3.81e-0520473MM15155
PathwayREACTOME_SYNAPTIC_ADHESION_LIKE_MOLECULES

GRIA1 GRIN2A GRIN2B

4.43e-0521473M27736
PathwayREACTOME_UNBLOCKING_OF_NMDA_RECEPTORS_GLUTAMATE_BINDING_AND_ACTIVATION

GRIA1 GRIN2A GRIN2B

4.43e-0521473M838
PathwayREACTOME_REGULATION_OF_FZD_BY_UBIQUITINATION

FZD4 FZD8 FZD5

4.43e-0521473M27401
PathwayWP_TRIACYLGLYCERIDE_SYNTHESIS

GK GK2 GNPAT

5.87e-0523473MM15890
PathwayWP_TRIACYLGLYCERIDE_SYNTHESIS

GK GK2 GNPAT

6.69e-0524473M39692
PathwayPID_REELIN_PATHWAY

MAP3K11 GRIN2A GRIN2B

1.07e-0428473M69
PathwayKEGG_MEDICUS_REFERENCE_TRANSPORT_OF_CALCIUM

GRIN2A GRIN2B

1.08e-045472M47667
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLCO1B7 SLC44A1 SLC9A5 SLC28A2 SLC5A8 SLC14A2

1.31e-04238476MM15076
PathwayREACTOME_SIGNALING_BY_WNT

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

1.34e-04239476MM14756
PathwayREACTOME_DISASSEMBLY_OF_THE_DESTRUCTION_COMPLEX_AND_RECRUITMENT_OF_AXIN_TO_THE_MEMBRANE

FZD1 FZD5 FZD2

1.46e-0431473M27400
PathwayREACTOME_DISASSEMBLY_OF_THE_DESTRUCTION_COMPLEX_AND_RECRUITMENT_OF_AXIN_TO_THE_MEMBRANE

FZD1 FZD5 FZD2

1.46e-0431473MM15154
PathwayWP_BREAST_CANCER_PATHWAY

FZD1 FZD7 FZD8 FZD5 FZD2

1.54e-04154475M39739
PathwayPID_WNT_NONCANONICAL_PATHWAY

FZD7 FZD5 FZD2

1.61e-0432473M23
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PDYN_TO_TRANSPORT_OF_CALCIUM

GRIN2A GRIN2B

1.62e-046472M47668
PathwayREACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT

FZD1 FZD4 FZD8 FZD5 FZD2

1.74e-04158475MM14791
PathwayREACTOME_SIGNALING_BY_WNT_IN_CANCER

FZD4 FZD8 FZD5

1.93e-0434473M27405
PathwayWP_GPCRS_NONODORANT

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

2.39e-04266476MM15843
PathwayWP_CANCER_PATHWAYS

FZD1 FZD4 FZD7 JAK2 FZD8 FZD5 APAF1 FZD2

2.42e-04507478M48302
PathwayREACTOME_ACTIVATION_OF_NMDA_RECEPTORS_AND_POSTSYNAPTIC_EVENTS

ERBB4 GRIA1 GRIN2A GRIN2B

2.66e-0494474M2843
PathwayPID_ERBB4_PATHWAY

JAK2 ERBB4 GRIN2B

2.70e-0438473M13
PathwayWP_GPCRS_OTHER

FZD1 FZD7 FZD5 FZD2

2.88e-0496474MM15939
PathwayREACTOME_CA2_PATHWAY

FZD4 FZD5 FZD2

4.47e-0445473MM15040
PathwayREACTOME_UPTAKE_OF_DIETARY_COBALAMINS_INTO_ENTEROCYTES

CTRB2 CTRB1

4.81e-0410472M45024
PathwayREACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION

ERBB4 GRIA1 GRIK3 GRIN2A GRIN2B

5.78e-04205475M752
PathwayWP_IDO_METABOLIC_PATHWAY

KYAT3 KYAT1

5.87e-0411472M48109
PathwayKEGG_PATHWAYS_IN_CANCER

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

6.94e-04325476M12868
PathwayREACTOME_WNT5A_DEPENDENT_INTERNALIZATION_OF_FZD2_FZD5_AND_ROR2

FZD5 FZD2

7.03e-0412472MM15163
PathwayREACTOME_TRIGLYCERIDE_BIOSYNTHESIS

GK GK2

7.03e-0412472MM15447
PathwayREACTOME_SIGNALING_BY_WNT

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

7.52e-04330476M7847
PathwayWP_PHOSPHODIESTERASES_IN_NEURONAL_FUNCTION

GRIA1 GRIN2A GRIN2B

8.07e-0455473M39763
PathwayREACTOME_WNT5A_DEPENDENT_INTERNALIZATION_OF_FZD2_FZD5_AND_ROR2

FZD5 FZD2

8.29e-0413472M27415
PathwayREACTOME_TRIGLYCERIDE_BIOSYNTHESIS

GK GK2

9.65e-0414472M619
PathwayREACTOME_TRYPTOPHAN_CATABOLISM

KYAT3 KYAT1

9.65e-0414472M1084
PathwayREACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT

FZD1 FZD4 FZD8 FZD5 FZD2

1.03e-03233475M27099
PathwayBIOCARTA_NO2IL12_PATHWAY

JAK2 CD4

1.11e-0315472M6231
PathwayBIOCARTA_NO2IL12_PATHWAY

JAK2 CD4

1.11e-0315472MM1446
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_TRANSPORT_OF_CALCIUM

GRIN2A GRIN2B

1.11e-0315472M47691
PathwayREACTOME_CA2_PATHWAY

FZD4 FZD5 FZD2

1.14e-0362473M27321
PathwayWP_NEUROINFLAMMATION_AND_GLUTAMATERGIC_SIGNALING

GRIA1 GRIK3 GRIN2A GRIN2B

1.19e-03140474M42572
PathwayWP_ADHD_AND_AUTISM_ASD_PATHWAYS

GK GRIA1 KYAT3 GRIN2A GRIN2B KYAT1

1.30e-03367476M48346
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC44A1 SLC9A5 SLC28A2 SLC5A8 SLC14A2

1.38e-03249475M5988
PathwayREACTOME_MECP2_REGULATES_NEURONAL_RECEPTORS_AND_CHANNELS

GRIN2A GRIN2B

1.61e-0318472M27901
PathwayKEGG_LONG_TERM_POTENTIATION

GRIA1 GRIN2A GRIN2B

1.63e-0370473M3115
PathwayWP_MESODERMAL_COMMITMENT_PATHWAY

FZD4 JAK2 FZD8 FZD5

1.66e-03153474M39546
PathwayWP_ALZHEIMERS_DISEASE

APAF1 GRIN2A GRIN2B

1.91e-0374473MM15962
PathwayREACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES

ERBB4 GRIA1 GRIK3 GRIN2A GRIN2B

1.97e-03270475M15514
PathwayBIOCARTA_NOS1_PATHWAY

GRIN2A GRIN2B

1.99e-0320472MM1445
PathwayREACTOME_SYNAPTIC_ADHESION_LIKE_MOLECULES

GRIA1 GRIN2A

1.99e-0320472MM15485
PathwayBIOCARTA_NOS1_PATHWAY

GRIN2A GRIN2B

2.19e-0321472M11650
PathwayREACTOME_NEGATIVE_REGULATION_OF_NMDA_RECEPTOR_MEDIATED_NEURONAL_TRANSMISSION

GRIN2A GRIN2B

2.19e-0321472M27944
PathwayKEGG_ALZHEIMERS_DISEASE

APAF1 GRIN2A GRIN2B NDUFC1

2.23e-03166474M16024
PathwayREACTOME_NEURONAL_SYSTEM

ERBB4 KCNQ5 GRIA1 GRIK3 GRIN2A GRIN2B

2.31e-03411476M735
PathwayREACTOME_UNBLOCKING_OF_NMDA_RECEPTORS_GLUTAMATE_BINDING_AND_ACTIVATION

GRIA1 GRIN2A

2.41e-0322472MM15104
PathwayREACTOME_COBALAMIN_CBL_VITAMIN_B12_TRANSPORT_AND_METABOLISM

CTRB2 CTRB1

2.41e-0322472M27084
PathwayBIOCARTA_CASPASE_PATHWAY

APAF1 LMNB2

2.41e-0322472M17902
PathwayREACTOME_TRIGLYCERIDE_METABOLISM

GK GK2

2.63e-0323472MM15575
PathwayWP_MTHFR_DEFICIENCY

GRIN2A DNMT3A

2.87e-0324472M39755
PathwayREACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES

GRIA1 GRIN2A GRIN2B

3.03e-0387473M27617
Pubmed

Expression of Frizzled genes in developing and postnatal hair follicles.

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

7.02e-151065615245425
Pubmed

Essential roles of mesenchyme-derived beta-catenin in mouse Müllerian duct morphogenesis.

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

7.02e-151065617532316
Pubmed

Frizzled-9 impairs acetylcholine receptor clustering in skeletal muscle cells.

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

1.54e-141165624860427
Pubmed

Molecular determinants of WNT9b responsiveness in nephron progenitor cells.

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

1.54e-141165630978219
Pubmed

Distinct but redundant expression of the Frizzled Wnt receptor genes at signaling centers of the developing mouse brain.

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

1.54e-141165617582687
Pubmed

Expression of Frizzled5, Frizzled7, and Frizzled10 during early mouse development and interactions with canonical Wnt signaling.

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

1.54e-141165617576136
Pubmed

Autosomal dominant familial exudative vitreoretinopathy in two Japanese families with FZD4 mutations (H69Y and C181R).

FZD1 FZD4 FZD7 FZD8 FZD5

4.08e-13765515370539
Pubmed

Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families.

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

4.09e-131765628733458
Pubmed

Differential expression of the Wnt putative receptors Frizzled during mouse somitogenesis.

FZD1 FZD4 FZD7 FZD8 FZD5

1.09e-12865510559494
Pubmed

A novel frizzled gene identified in human esophageal carcinoma mediates APC/beta-catenin signals.

FZD1 FZD4 FZD7 FZD5 FZD2

2.44e-1296559707618
Pubmed

Expression of the Wnt inhibitor Dickkopf-1 is required for the induction of neural markers in mouse embryonic stem cells differentiating in response to retinoic acid.

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

2.45e-122265617064353
Pubmed

A role for Wnt/beta-catenin signaling in lens epithelial differentiation.

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

5.79e-122565612812787
Pubmed

3D representation of Wnt and Frizzled gene expression patterns in the mouse embryo at embryonic day 11.5 (Ts19).

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

1.54e-112965618364260
Pubmed

Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development.

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

6.27e-113665624151333
Pubmed

Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis.

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

7.47e-113765615342465
Pubmed

Patterns of Wnt/Fzd/LRP gene expression during embryonic hematopoiesis.

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

7.47e-113765618800919
Pubmed

Wnt11 promotes cardiomyocyte development by caspase-mediated suppression of canonical Wnt signals.

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

8.86e-113865621041481
Pubmed

Tissue-specific requirements of beta-catenin in external genitalia development.

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

8.86e-113865618635608
Pubmed

Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells.

FZD1 FZD7 FZD8 FZD5 FZD2

2.22e-101965521623369
Pubmed

Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis.

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

3.40e-104765628813421
Pubmed

Members of the WNT signaling pathways are widely expressed in mouse ovaries, oocytes, and cleavage stage embryos.

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

3.40e-104765618351675
Pubmed

Malformation of Tear Ducts Underlies the Epiphora and Precocious Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for Tear Duct Genesis.

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

3.40e-104765633141892
Pubmed

MAGI-3 is involved in the regulation of the JNK signaling pathway as a scaffold protein for frizzled and Ltap.

FZD4 FZD7 FZD8 FZD5

3.87e-10765415195140
Pubmed

Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells.

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

4.42e-104965619562671
Pubmed

Brg1 plays an essential role in development and homeostasis of the duodenum through regulation of Notch signaling.

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

5.01e-105065627510977
Pubmed

Transmembrane topology of the glutamate receptor subunit GluR6.

GRIA1 GRIK3 GRIN2A GRIN2B

7.73e-1086548163463
Pubmed

Sequence requirement and subtype specificity in the high-affinity interaction between human frizzled and dishevelled proteins.

FZD1 FZD4 FZD7 FZD2

7.73e-10865419388021
Pubmed

A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors.

FZD4 FZD7 FZD8 FZD5 FZD2

8.06e-10246559096311
Pubmed

A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled.

FZD4 FZD7 FZD8 FZD5 FZD2

8.06e-10246558626800
Pubmed

Direct interaction of Frizzled-1, -2, -4, and -7 with PDZ domains of PSD-95.

FZD1 FZD4 FZD7 FZD2

1.39e-09965412067714
Pubmed

Molecular cloning, differential expression, and chromosomal localization of human frizzled-1, frizzled-2, and frizzled-7.

FZD1 FZD7 FZD2

6.23e-0936539813155
Pubmed

Frizzled proteins are colonic epithelial receptors for C. difficile toxin B.

FZD1 FZD7 FZD2

6.23e-09365327680706
Pubmed

Expression patterns of Wnts, Frizzleds, sFRPs, and misexpression in transgenic mice suggesting a role for Wnts in pancreas and foregut pattern formation.

FZD4 FZD7 FZD8 FZD5 FZD2

7.03e-093665512412008
Pubmed

Integrated analysis of Wnt signalling system component gene expression.

FZD1 FZD4 FZD7 FZD8 FZD5

8.11e-093765535831952
Pubmed

Conditional mutations of beta-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation.

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

1.85e-089065619515997
Pubmed

Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.

ERVK-6 ERVK-7 ERVK-10

2.49e-08465310469592
Pubmed

Reelin signaling facilitates maturation of CA1 glutamatergic synapses.

GRIA1 GRIN2A GRIN2B

6.21e-08565317229826
Pubmed

Non-association between polymorphisms of the frizzled receptor genes and bone mineral density in postmenopausal Korean women.

FZD1 FZD7 FZD5

6.21e-08565319543507
Pubmed

NMDA receptor subunits and associated signaling molecules mediating antidepressant-related effects of NMDA-GluN2B antagonism.

GRIA1 GRIN2A GRIN2B

6.21e-08565325800971
Pubmed

Protein kinase C is differentially stimulated by Wnt and Frizzled homologs in a G-protein-dependent manner.

FZD4 FZD7 FZD8

6.21e-08565310395542
Pubmed

PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

8.95e-0811765617145500
Pubmed

Glutamate can act as a signaling molecule in mouse preimplantation embryos†.

GRIA1 GRIK3 GRIN2A GRIN2B

1.15e-072465435746896
Pubmed

Direct interaction between NHERF1 and Frizzled regulates β-catenin signaling.

FZD4 FZD7 FZD2

1.24e-07665320802536
Pubmed

FZD2 regulates limb development by mediating β-catenin-dependent and -independent Wnt signaling pathways.

FZD1 FZD7 FZD2

1.24e-07665336867021
Pubmed

Slitrk5 deficiency impairs corticostriatal circuitry and leads to obsessive-compulsive-like behaviors in mice.

GRIA1 GRIN2A GRIN2B

1.24e-07665320418887
Pubmed

Vulnerability of white matter towards antenatal hypoxia is linked to a species-dependent regulation of glutamate receptor subunits.

GRIA1 GRIK3 GRIN2B

1.24e-07665318922769
Pubmed

Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action.

FZD7 FZD8 FZD5

2.17e-0776539192640
Pubmed

Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3.

GRIA1 GRIN2A GRIN2B

2.17e-07765321558424
Pubmed

Wnt signaling is required for thymocyte development and activates Tcf-1 mediated transcription.

FZD7 FZD8 FZD5

2.17e-07765311265645
Pubmed

Wnt7b activates canonical signaling in epithelial and vascular smooth muscle cells through interactions with Fzd1, Fzd10, and LRP5.

FZD1 FZD4 FZD7

2.17e-07765315923619
Pubmed

Low density lipoprotein receptor-related protein 1 (LRP1) modulates N-methyl-D-aspartate (NMDA) receptor-dependent intracellular signaling and NMDA-induced regulation of postsynaptic protein complexes.

GRIA1 GRIN2A GRIN2B

2.17e-07765323760271
Pubmed

Specific assembly with the NMDA receptor 3B subunit controls surface expression and calcium permeability of NMDA receptors.

GRIA1 GRIN2A GRIN2B

3.47e-07865314602821
Pubmed

A coated vesicle-associated kinase of 104 kDa (CVAK104) induces lysosomal degradation of frizzled 5 (Fzd5).

FZD1 FZD4 FZD5

3.47e-07865319643732
Pubmed

Frizzled 2 and frizzled 7 function redundantly in convergent extension and closure of the ventricular septum and palate: evidence for a network of interacting genes.

FZD1 FZD7 FZD2

5.19e-07965323095888
Pubmed

A role for the Wnt gene family in hematopoiesis: expansion of multilineage progenitor cells.

FZD4 FZD7 FZD5

5.19e-0796539160667
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-6 ERVK-8 ERVK-7 ERVK-10 ERVK-11

9.41e-079465521542922
Pubmed

Ephrin-A5 and EphA5 interaction induces synaptogenesis during early hippocampal development.

GRIA1 GRIN2A GRIN2B

1.02e-061165320824214
Pubmed

ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner.

FZD4 FZD8 FZD5

1.02e-061165322575959
Pubmed

Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms.

CLCN3 GRIA1 GRIN2A GRIN2B

1.56e-064565425979088
Pubmed

Ambra1 Shapes Hippocampal Inhibition/Excitation Balance: Role in Neurodevelopmental Disorders.

GRIA1 GRIN2A GRIN2B

1.76e-061365329488136
Pubmed

The deubiquitinase USP6 affects memory and synaptic plasticity through modulating NMDA receptor stability.

GRIA1 GRIN2A GRIN2B

1.76e-061365331841517
Pubmed

Role of chromatin remodeling gene Cecr2 in neurulation and inner ear development.

FZD1 FZD7 FZD2

1.76e-061365321246654
Pubmed

Glutamatergic gene variants impact the clinical profile of efficacy and side effects of haloperidol.

GRIA1 GRIK3 GRIN2B

1.76e-061365320859245
Pubmed

Novel cell surface genes expressed in the stomach primordium during gastrointestinal morphogenesis of mouse embryos.

FZD7 FZD8 FZD5

1.76e-061365322266179
Pubmed

Impaired maturation of dendritic spines without disorganization of cortical cell layers in mice lacking NRG1/ErbB signaling in the central nervous system.

ERBB4 GRIN2A GRIN2B

2.23e-061465319240213
Pubmed

WNT signaling affects gene expression in the ventral diencephalon and pituitary gland growth.

FZD1 FZD4 FZD8 FZD2

2.40e-065065418351662
Pubmed

Dickkopf-1 (DKK1) reveals that fibronectin is a major target of Wnt signaling in branching morphogenesis of the mouse embryonic lung.

FZD7 FZD8 FZD2

2.79e-061565315617677
Pubmed

Transferrin Receptor Controls AMPA Receptor Trafficking Efficiency and Synaptic Plasticity.

GRIA1 GRIN2A GRIN2B

2.79e-061565326880306
Pubmed

Adjacent asparagines in the NR2-subunit of the NMDA receptor channel control the voltage-dependent block by extracellular Mg2+.

GRIA1 GRIN2A GRIN2B

2.79e-06156539481670
Pubmed

Early Correction of N-Methyl-D-Aspartate Receptor Function Improves Autistic-like Social Behaviors in Adult Shank2-/- Mice.

GRIA1 GRIN2A GRIN2B

3.43e-061665330466882
Pubmed

The glutamate receptor GluN2 subunit regulates synaptic trafficking of AMPA receptors in the neonatal mouse brain.

GRIN2A GRIN2B

3.44e-06265225131300
Pubmed

Brain-region-specific changes in neurons and glia and dysregulation of dopamine signaling in Grin2a mutant mice.

GRIN2A GRIN2B

3.44e-06265237657442
Pubmed

Individual NMDA receptor GluN2 subunit signaling domains differentially regulate the postnatal maturation of hippocampal excitatory synaptic transmission and plasticity but not dendritic morphology.

GRIN2A GRIN2B

3.44e-06265238813758
Pubmed

Chymotrypsin Reduces the Severity of Secretagogue-Induced Pancreatitis in Mice.

CTRB2 CTRB1

3.44e-06265230076839
Pubmed

Jak2V617F and Dnmt3a loss cooperate to induce myelofibrosis through activated enhancer-driven inflammation.

JAK2 DNMT3A

3.44e-06265230366920
Pubmed

The CTRB1-CTRB2 risk allele for chronic pancreatitis discovered in European populations does not contribute to disease risk variation in the Chinese population due to near allele fixation.

CTRB2 CTRB1

3.44e-06265228951524
Pubmed

Dual Role of NMDAR Containing NR2A and NR2B Subunits in Alzheimer's Disease.

GRIN2A GRIN2B

3.44e-06265238731978
Pubmed

Neurotoxic lupus autoantibodies alter brain function through two distinct mechanisms.

GRIN2A GRIN2B

3.44e-06265220921396
Pubmed

Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis.

CTRB2 CTRB1

3.44e-06265228754779
Pubmed

Differential Nanoscale Topography and Functional Role of GluN2-NMDA Receptor Subtypes at Glutamatergic Synapses.

GRIN2A GRIN2B

3.44e-06265230269991
Pubmed

The GRIN2B and GRIN2A Gene Variants Are Associated With Continuous Performance Test Variables in ADHD.

GRIN2A GRIN2B

3.44e-06265227199241
Pubmed

The role of NMDAR subtypes and charge transfer during hippocampal LTP induction.

GRIN2A GRIN2B

3.44e-06265216901514
Pubmed

Downregulation of hippocampal NR2A/2B subunits related to cognitive impairment in a pristane-induced lupus BALB/c mice.

GRIN2A GRIN2B

3.44e-06265231498792
Pubmed

Sequencing of the complex CTRB1-CTRB2 locus in chronic pancreatitis.

CTRB2 CTRB1

3.44e-06265233036922
Pubmed

Role of major NMDA or AMPA receptor subunits in MK-801 potentiation of ethanol intoxication.

GRIA1 GRIN2A

3.44e-06265218565157
Pubmed

Age-Dependent Changes in Synaptic NMDA Receptor Composition in Adult Human Cortical Neurons.

GRIN2A GRIN2B

3.44e-06265232191258
Pubmed

Specific involvement of postsynaptic GluN2B-containing NMDA receptors in the developmental elimination of corticospinal synapses.

GRIN2A GRIN2B

3.44e-06265220696923
Pubmed

Distinct roles of GRIN2A and GRIN2B variants in neurological conditions.

GRIN2A GRIN2B

3.44e-06265231807283
Pubmed

NMDA receptor subunit composition determines beta-amyloid-induced neurodegeneration and synaptic loss.

GRIN2A GRIN2B

3.44e-06265223618906
Pubmed

The role of GluN2A and GluN2B NMDA receptor subunits in AgRP and POMC neurons on body weight and glucose homeostasis.

GRIN2A GRIN2B

3.44e-06265226500840
Pubmed

Evolutionary relationships between laboratory mice and subspecies of Mus musculus based on the restriction fragment length variants of the chymotrypsin gene at the Prt-2 locus.

CTRB2 CTRB1

3.44e-0626522565717
Pubmed

Both NR2A and NR2B subunits of the NMDA receptor are critical for long-term potentiation and long-term depression in the lateral amygdala of horizontal slices of adult mice.

GRIN2A GRIN2B

3.44e-06265219474217
Pubmed

Chronic early postnatal scream sound stress induces learning deficits and NMDA receptor changes in the hippocampus of adult mice.

GRIN2A GRIN2B

3.44e-06265227015584
Pubmed

Loss of Dnmt3a increases self-renewal and resistance to pegIFN-α in JAK2-V617F-positive myeloproliferative neoplasms.

JAK2 DNMT3A

3.44e-06265238493481
Pubmed

Hippocampal NMDA receptor subunits differentially regulate fear memory formation and neuronal signal propagation.

GRIN2A GRIN2B

3.44e-06265219806658
Pubmed

Importance of the GluN2B carboxy-terminal domain for enhancement of social memories.

GRIN2A GRIN2B

3.44e-06265226179233
Pubmed

Melanocyte stem cells express receptors for canonical Wnt-signaling pathway on their surface.

FZD4 FZD7

3.44e-06265220450888
Pubmed

Subtype selective NMDA receptor antagonists induce recovery of synapses lost following exposure to HIV-1 Tat.

GRIN2A GRIN2B

3.44e-06265222142193
Pubmed

Conformational rearrangement of the NMDA receptor amino-terminal domain during activation and allosteric modulation.

GRIN2A GRIN2B

3.44e-06265233976221
Pubmed

Lack of NMDA receptor subtype selectivity for hippocampal long-term potentiation.

GRIN2A GRIN2B

3.44e-06265216033900
InteractionDLG2 interactions

FZD1 FZD4 FZD7 ERBB4 GRIA1 GRIN2A GRIN2B

3.94e-0983587int:DLG2
InteractionDLG4 interactions

FZD1 FZD4 FZD7 ERBB4 MAP3K11 GRIA1 GRIN2A GRIN2B FZD2

5.05e-06449589int:DLG4
InteractionSCGB1C1 interactions

FZD1 FZD7 FZD2

6.34e-0613583int:SCGB1C1
InteractionCTRB2 interactions

CTRB2 CTRB1

2.44e-053582int:CTRB2
InteractionWNT5A interactions

FZD1 FZD4 FZD5 FZD2

4.64e-0569584int:WNT5A
InteractionLYPD3 interactions

SLC44A1 CLCN3 SCAMP3 CTRB1 GNPAT

5.31e-05141585int:LYPD3
InteractionOR1D4 interactions

FZD7 FZD8 FZD2

5.61e-0526583int:OR1D4
InteractionDLG1 interactions

FZD4 FZD7 ERBB4 GRIA1 GRIN2A GRIN2B

6.46e-05240586int:DLG1
InteractionSLC35B1 interactions

FZD7 FZD5 FKBP8

7.04e-0528583int:SLC35B1
InteractionUPK1A interactions

FZD1 FZD7 FZD8 SLC44A1 FZD2

7.13e-05150585int:UPK1A
InteractionGRIK2 interactions

MAP3K11 GRIA1 GRIK3

1.06e-0432583int:GRIK2
InteractionSLC25A46 interactions

CHMP7 GK LMNB2 SLC5A8 FKBP8 MFN1

1.16e-04267586int:SLC25A46
InteractionZNRF3 interactions

FZD4 FZD7 NRSN1

1.39e-0435583int:ZNRF3
InteractionGK interactions

GK GK2 SLC5A8 FKBP8

1.49e-0493584int:GK
InteractionGRIN2A interactions

GRIA1 GRIN2A GRIN2B HERC2

1.49e-0493584int:GRIN2A
InteractionCTRB1 interactions

CTRB2 CTRB1

1.69e-047582int:CTRB1
Cytoband14q22.2

CGRRF1 SLC35F4

8.82e-051065214q22.2
Cytoband4q23

ADH5 TSPAN5

3.69e-04206524q23
Cytoband16q23.1

CTRB2 CTRB1

9.53e-043265216q23.1
CytobandEnsembl 112 genes in cytogenetic band chr4q23

ADH5 TSPAN5

1.27e-0337652chr4q23
GeneFamilyG protein-coupled receptors, Class F frizzled

FZD1 FZD4 FZD7 FZD8 FZD5 FZD2

8.84e-1411466286
GeneFamilySolute carriers

SLCO1B7 SLC44A1 SLC9A5 SLC28A2 SLC35G2 SLC5A8 SLC9C2 SLC14A2 SLC35F4

5.58e-07395469752
GeneFamilyGlycerol kinases

GK GK2

9.44e-056462568
GeneFamilyGlutamate ionotropic receptor NMDA type subunits

GRIN2A GRIN2B

1.32e-0474621201
GeneFamilyCD molecules|Tetraspanins

TSPAN14 TSPAN5

3.18e-0333462768
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

CD4 KIRREL2

4.64e-0340462592
CoexpressionGSE1460_NAIVE_CD4_TCELL_CORD_BLOOD_VS_THYMIC_STROMAL_CELL_UP

FZD8 CHMP7 SLC44A1 MAN1C1 MAP3K11 HERC2

5.30e-06193606M3484
CoexpressionVART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN

FZD1 FZD7 FZD8 FZD5 FZD2

1.46e-05135605M5825
CoexpressionGU_PDEF_TARGETS_UP

FZD1 FZD4 FZD8 COL6A2

2.15e-0571604M3955
ToppCellfacs-Skin-Anagen-3m-Epithelial-bulge_keratinocyte|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD1 FZD7 COL6A2 SPART FZD2

6.22e-06193605eba3c70701b051bc1ed1f4db9270cb27a77ffc3e
ToppCellfacs-Skin-Anagen-3m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD1 FZD7 COL6A2 SPART FZD2

6.38e-061946055d30d3d41d5f19cdf3077cc609aa2738762cb8c5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC44A1 TENM3 SLC14A2 TSPAN5

3.93e-05141604091b5b72811db5fca2314f4a79d467566920e257
ToppCellNS-critical-LOC-Myeloid-Basophil|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FZD1 FZD7 SLC44A1 SLC14A2

6.43e-051606048a4746463ca1976f7d6de803496c851249ced797
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TENM3 GRIA1 GRIK3 GRIN2B

6.75e-05162604d28b2ea1d2c8f3c6a107991573471b6d0c49c4ae
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TENM3 MAN1C1 SPART GRIN2A

6.75e-05162604bfaeff19bb56598fdc8c82be71d51787cf13928f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TENM3 GRIA1 GRIK3 GRIN2B

6.75e-051626045bbd7130d4dad9035e73a439dda568195c136f31
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TENM3 GRIA1 GRIK3 GRIN2B

6.75e-05162604eed223e61c8162a2fe004ab4e09de5e037be7553
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TENM3 GRIA1 GRIK3 GRIN2B

6.75e-05162604e35ddce830e20ebeac1a2c405293fc4a5323dd4a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FZD1 COL6A2 CD4 ANGPTL5

7.25e-051656044f83ac71efc57be3668d8db1e62bad05dc6a5e2b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FZD1 COL6A2 CD4 ANGPTL5

7.25e-05165604cd8de98af8a1a8a6c81d71fae807cc07f319f4c9
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD4 KCNQ5 TENM3 GRIN2B

7.77e-05168604b87fc63f9e35dfcfc46cb129ea569e73c5e018bb
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD4 KCNQ5 TENM3 GRIN2B

7.77e-05168604b96a48552f4236a95bbcdce2f1b05041086d7101
ToppCellAdult-Endothelial-endothelial_cell_of_vein-D175|Adult / Lineage, Cell type, age group and donor

FZD4 PLA1A GRIN2B SLC35F4

7.95e-05169604e1f0298236e4a1c59077c14f0dd29a78fac12648
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Lgr5+_undifferentiated_cell_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD1 CWH43 FZD5 SLC5A8

8.13e-05170604833b4f44ea1fa673dfc6b43ce45a79fe68ae3b05
ToppCellmetastatic_Brain-B_lymphocytes-Undetermined|B_lymphocytes / Location, Cell class and cell subclass

JAK2 CD4 KCNQ5 SLC14A2

8.32e-051716040d14bc9688c427ba2265984987dc3eea195b19eb
ToppCellCOVID-19-Heart-Neuronal|Heart / Disease (COVID-19 only), tissue and cell type

TENM3 GRIA1 GRIK3 TSPAN5

8.70e-051736046fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCellnormal_Lymph_Node-Myeloid_cells-pDCs|normal_Lymph_Node / Location, Cell class and cell subclass

CLCN3 FZD2 MFN1 RSKR

9.30e-05176604476794ef75ce5ab732d78cfeb4944e2f841e3e92
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

ERBB4 TENM3 TSPAN5 SLC35F4

9.72e-05178604544379f5a6145429762258d426b876bb36c112f5
ToppCelldroplet-Fat-Scat-21m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A2 CWH43 PLA1A GRIK3

9.72e-051786045fc9f41609735b972a2cd0830182d13742cd5bf5
ToppCell390C-Fibroblasts-Fibroblast-G|390C / Donor, Lineage, Cell class and subclass (all cells)

COL6A2 TENM3 MAN1C1 GRIA1

1.01e-04180604137fc14859c89e1ecd98bee388bb58c04b835847
ToppCellRA-16._Neuronal|RA / Chamber and Cluster_Paper

TENM3 GRIA1 GRIK3 TSPAN5

1.01e-041806045842febfdabac61ce970254fb0ef17a628f1b8c0
ToppCell390C-Fibroblasts-Fibroblast-G-|390C / Donor, Lineage, Cell class and subclass (all cells)

COL6A2 TENM3 MAN1C1 GRIA1

1.01e-04180604cd6790de050151fedfa2c5ea6ad58b72665414b2
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 CWH43 MAN1C1 SLC14A2

1.04e-04181604aa233b652921848af2257cc3687a7a09c3acfb67
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC44A1 CWH43 MAN1C1 TSPAN5

1.04e-04181604b7c85fbef3c06d5dc32a2a58f8d3dfabf1d79d9f
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 GRIK3 SLC5A8 SLC35F4

1.08e-04183604121791ef84e7ce377ed6f5b7953af8865e04958e
ToppCellwk_15-18-Epithelial-PNS-intermediate_Schwann|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TENM3 GRIK3 SLC5A8 KIRREL2

1.08e-04183604d874aa9a856f79626c8a8371f6196a77b7d662ee
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 TENM3 GRIK3 SLC35F4

1.08e-0418360404d3cc76038b8192c915f1c08c3e26f2ad3b3779
ToppCellwk_20-22-Epithelial-PNS-intermediate_Schwann|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

TENM3 GRIK3 GRIN2B KIRREL2

1.10e-041846044e3ba64692868563a579902aa9c6f88cab5bce26
ToppCellAnterior_Cingulate_gyrus_(CgG)|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 TENM3 GRIA1 ANGPTL5

1.15e-0418660432af3f211f9ad5d5c6b86b83325cfbf2f8466b56
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CWH43 MAN1C1 GRIN2B TSPAN5

1.17e-041876042d17408b3b5f09d135084fd7ccce98e6b5ca632b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC44A1 CWH43 MAN1C1 TSPAN5

1.20e-0418860458ccb31cdf43167872ef0fc737e6f9c51ee2e060
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 TENM3 GRIK3 SLC35F4

1.20e-041886048de5a07301f9b5984680c873e5a92395b5ed3dd3
ToppCellwk_08-11-Epithelial-PNS-intermediate_Schwann|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

TENM3 GRIK3 SLC5A8 KIRREL2

1.20e-041886043f3a744b2615bf72f6119f26087099110c0d21fc
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD4 KCNQ5 GRIN2B NRSN1

1.22e-041896043e8e30160a8d6f531ff743cb5918c9e79481f1bd
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC44A1 CWH43 GRIN2B TSPAN5

1.22e-04189604c9565e962a13a7713056ec3dbb1b67d24f9889c7
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD4 KCNQ5 GRIN2B NRSN1

1.22e-04189604851f8144aed5c7f80302911cd6b03f14bde7b56d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC44A1 CWH43 MAN1C1 TSPAN5

1.22e-04189604532aaf02b364c5c4f58a2021c7c21d86df3875c9
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 TENM3 GRIK3 SLC35F4

1.25e-04190604d19bc44310c53726e2f5f6a2bd377bbbf1d1983f
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD4 KCNQ5 GRIN2B NRSN1

1.25e-041906041c5cf933ce71fed5638b9ef31eb81f6c2b6dadbc
ToppCellGlobus_pallidus-Neuronal|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SLC9A5 GRIN2A GRIN2B NRSN1

1.25e-04190604416de85d8841dac883faa6f5339b2fb461a09e82
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 TENM3 GRIK3 SLC35F4

1.25e-041906043f22c118d552345f731d4d49f0bcb5765d93de3b
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 TENM3 GRIK3 SLC35F4

1.25e-04190604305fbef734c350cfbf786ca7ff6e07093aab56ea
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 TENM3 GRIK3 SLC35F4

1.25e-041906048c9c230a509afaeee50644153974a5642b01a2b8
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

COL6A2 TENM3 GRIA1 TSPAN5

1.25e-041906044f775ee24b14733f06ae40b45f2dc1a0f0df0705
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 TENM3 GRIK3 SLC35F4

1.25e-04190604e58e4b6fbeb4368f738adac67ec10879c0966f0f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC44A1 TENM3 SLC14A2 TSPAN5

1.27e-041916043e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ERBB4 GRIN2A GRIN2B KIRREL2

1.27e-041916044c4eb61e6179d2f8fc524d2f813db9cba84f67a2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC44A1 MAN1C1 GRIN2B TSPAN5

1.30e-04192604fd08ae787e936cfdb1ab8f19b0fd63005b462709
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC44A1 MAN1C1 GRIN2B TSPAN5

1.30e-04192604bae236c9f1fac77bce28d0a9cf090100d391ff77
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 TENM3 GRIK3 SLC35F4

1.30e-041926040003d7ef9a8e521e70ac33c63aad843d9b6215c2
ToppCellCOVID-19_Convalescent-CD4+_T_naive|COVID-19_Convalescent / Disease condition and Cell class

CHMP7 CD4 MAN1C1 DNMT3A

1.33e-04193604346caaf288217acaf232060629ce964a07f63432
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

UBE2O CLCN3 FZD5 TSPAN5

1.33e-04193604305e15ee467826ee08b2617c69f250ad39c11b19
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

COL6A2 TENM3 GRIA1 TSPAN5

1.33e-04193604adc9fc94f9ec686a417d08c0b8b7b7ab687afec0
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 TENM3 GRIK3 SLC35F4

1.33e-0419360453bcd50892c379b2a571751f6eb1062436339fe7
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 TENM3 GRIK3 SLC35F4

1.33e-04193604c4b22b62f3cc7bf0ec0eba76e1504c236290bbc9
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-hematologic-erythrocytic|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

UBE2O CLCN3 FZD5 TSPAN5

1.33e-04193604dd376664906caccc9c2065f8e7a364509e18a5cc
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC44A1 TENM3 SLC14A2 TSPAN5

1.35e-0419460404bfc555743f7d8821439d05ae442d15e9886c59
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC44A1 TENM3 SLC14A2 TSPAN5

1.35e-0419460469bff17df4a760ccf081cf52ff04af02c14f448d
ToppCell10x3'2.3-week_17-19-Hematopoietic-erythroid-late_erythroid|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

UBE2O CLCN3 FKBP8 TSPAN5

1.35e-0419460423b06707d21306b4483d64cb350b86aef352ce38
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNQ5 GRIN2A GRIN2B NRSN1

1.38e-04195604ffbab350e67d9c4b66c0ab84550daec8b8139a27
ToppCellfacs-Skin-nan-18m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD7 TENM3 KIRREL2 FZD2

1.38e-04195604ba7cb80deb872c9184769f0dd57855c3c6a432bf
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNQ5 GRIA1 GRIN2A GRIN2B

1.41e-04196604676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell10x3'2.3-week_17-19-Hematopoietic-erythroid-mid_erythroid|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

UBE2O CLCN3 FKBP8 TSPAN5

1.41e-0419660451c48944149a89b98011a50fe81ca6664d5f0d44
ToppCell10x3'2.3-week_17-19-Hematopoietic|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

UBE2O CLCN3 FKBP8 TSPAN5

1.41e-041966042aeb792e7685e33e3543a6974be790980a41ed8c
ToppCell10x3'2.3-week_17-19-Hematopoietic-erythroid|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

UBE2O CLCN3 FKBP8 TSPAN5

1.44e-04197604b71da7f2fd8d526fb6e5d57e60fc08acdd8dbefb
ToppCellSmart-seq2-thymus_(Smart-seq2)-myeloid-myeloid_macrophage|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

JAK2 CD4 TSPAN14 SNX13

1.44e-04197604e3349a381723393cd255f202afedd0c99037939b
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FZD1 FZD8 COL6A2 FZD2

1.44e-041976043fe665c0277d091290b63f0dd24c0c6536a45309
ToppCellSmart-seq2-thymus_(Smart-seq2)-myeloid-myeloid_macrophage-macrophage|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

JAK2 CD4 TSPAN14 SNX13

1.44e-04197604e567886d69c6ea8dec87019c2ebc593793cb3107
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNQ5 GRIA1 GRIN2A GRIN2B

1.46e-04198604c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNQ5 GRIA1 GRIN2A GRIN2B

1.46e-041986046d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNQ5 GRIA1 GRIN2A GRIN2B

1.46e-041986044ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNQ5 GRIA1 GRIN2A GRIN2B

1.46e-041986040ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellCOVID-19-COVID-19_Severe-Others-RBC|COVID-19_Severe / Disease, condition lineage and cell class

UBE2O FZD5 FKBP8 TSPAN5

1.52e-04200604308f74e7e13ecc6d133c219c42cc8895a96644c8
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

KCNQ5 GRIA1 GRIN2A GRIN2B

1.52e-0420060448d801219bc771d6c7e151dc88ca4c179988de85
ToppCellTracheal-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

JAK2 COL6A2 TENM3 GRIN2B

1.52e-04200604f692b602bc989d35c9162e73dda813dbef8d5267
DrugA 172

FZD1 FZD4 FZD7 FZD8 FZD5 APAF1 FZD2

8.21e-1070627CID000014025
Drugaurintricarboxylic acid

JAK2 ERBB4 CD4 GRIA1 GRIK3 GRIN2A GRIN2B

5.30e-0991627CID000002259
DrugAC1L9M5J

FZD1 FZD4 FZD7 FZD8 FZD5 GRIA1 GRIK3 GRIN2A FZD2

8.44e-09221629CID000448615
DrugPrestwick_517

FZD1 FZD4 FZD7 FZD8 ERBB4 FZD5 FZD2

1.55e-08106627CID000003804
Drug6,7-dinitroquinoxaline

MAP3K11 GRIA1 GRIK3 GRIN2A GRIN2B

2.84e-0833625CID002724608
Drugkainite

MAP3K11 GRIA1 GRIK3 GRIN2A GRIN2B

3.87e-0835625CID000164810
Drug2-amino-3-phosphonopropionic acid

ADH5 APAF1 GRIA1 GRIK3 GRIN2A GRIN2B

6.00e-0876626CID000003857
Drugargiopine

GRIA1 GRIK3 GRIN2A GRIN2B

8.85e-0816624CID000122294
DrugIDRA 21

GRIA1 GRIK3 GRIN2A GRIN2B

2.34e-0720624CID000003688
DrugNS 102

GRIA1 GRIK3 GRIN2A GRIN2B

3.51e-0722624CID005282252
DrugCX516

GRIA1 GRIK3 GRIN2A GRIN2B

3.51e-0722624CID000148184
Drugdimethyloxalylglycine; Up 200; 1000uM; PC3; HG-U133A

FZD1 FZD8 UBE2O SLC9A5 SPART GRIN2B FKBP8

4.31e-07172627584_UP
DrugGYKI 52466

MAP3K11 GRIA1 GRIK3 GRIN2A GRIN2B

5.21e-0758625CID000003538
Drugifenprodil

GRIA1 GRIN2A GRIN2B

1.07e-068623ctd:C010739
Drugperzinfotel

GRIK3 GRIN2A GRIN2B

1.07e-068623CID006918236
DrugAC1NUW3V

GRIA1 GRIK3 GRIN2A GRIN2B

1.12e-0629624CID005462126
DrugL-Glutamic Acid

GRIA1 KYAT3 GRIK3 GRIN2A GRIN2B

1.16e-0668625DB00142
Drugcis-2,3-piperidine dicarboxylic acid

GRIA1 GRIK3 GRIN2A GRIN2B

1.30e-0630624CID000001226
DrugLY293558

GRIA1 GRIK3 GRIN2A GRIN2B

1.30e-0630624CID000127894
Drug4-methylglutamic acid

GRIA1 GRIK3 GRIN2A GRIN2B

1.48e-0631624CID000005365
DrugAC1L1DME

CD4 GRIA1 GRIK3 GRIN2A GRIN2B

1.89e-0675625CID000002414
Drug1-aminoindan-1,5-dicarboxylic acid

APAF1 GRIA1 GRIN2A GRIN2B

1.92e-0633624CID000002071
Drugclofazimine

FZD1 FZD4 FZD7 FZD2

2.45e-0635624CID000002794
DrugR,S)-AMPA

GRIA1 GRIK3 GRIN2A GRIN2B

2.75e-0636624CID000001221
Drugpilocarpine-

CTRB2 GRIA1 GRIK3 GRIN2A GRIN2B CTRB1

2.98e-06147626CID000004819
Druggamma-Glu-Gly

GRIA1 GRIK3 GRIN2A GRIN2B

3.08e-0637624CID000100099
DrugD-N-Q

MAP3K11 GRIA1 GRIK3 GRIN2A GRIN2B

3.32e-0684625CID000003140
DrugCGS 19755

GRIA1 GRIK3 GRIN2A GRIN2B

3.43e-0638624CID000068736
DrugGAMs

GRIA1 GRIK3 GRIN2A GRIN2B

3.43e-0638624CID000002935
DrugL-BMAA

GRIA1 GRIK3 GRIN2A GRIN2B

3.43e-0638624CID000028558
DrugDieldrin

ADH5 FZD1 FZD7 FZD8 SLC44A1 CGRRF1 APAF1 GRIA1 GRIK3 GRIN2B HERC2 COQ2 FZD2 KYAT1

3.76e-0612176214ctd:D004026
DrugDETC-MeSO

GRIA1 GRIK3 GRIN2A GRIN2B

3.82e-0639624CID003035711
DrugHA-966

GRIA1 GRIK3 GRIN2A GRIN2B

3.82e-0639624CID000001232
DrugLY341495

GRIA1 GRIK3 GRIN2A GRIN2B

5.68e-0643624CID006324636
DrugJoro spider toxin

GRIA1 GRIK3 GRIN2A GRIN2B

5.68e-0643624CID000119582
Drugphilanthotoxin

GRIA1 GRIK3 GRIN2A GRIN2B

6.83e-0645624CID000115201
Drug7-chlorokynurenic acid

GRIA1 GRIK3 GRIN2A GRIN2B

6.83e-0645624CID000001884
Drugc189

CTRB2 CTRB1

7.30e-062622CID000248048
DrugBOCPheONP

CTRB2 CTRB1

7.30e-062622CID000111308
Drugdansyl-D-arginine methyl ester

CTRB2 CTRB1

7.30e-062622CID000191369
DrugMPM-06

CTRB2 CTRB1

7.30e-062622CID000161546
Drugmethyl 6-phenylhexanoate

CTRB2 CTRB1

7.30e-062622CID011820300
DrugNSC-374899

CTRB2 CTRB1

7.30e-062622CID000435726
Drug5-aminotetrazole

CTRB2 CTRB1

7.30e-062622CID000020467
Drug2-bromoisobutyric acid

CTRB2 CTRB1

7.30e-062622CID000074924
Drugp-toluamidine

CTRB2 CTRB1

7.30e-062622CID000122753
Drugmethylbenzenebutanoate

CTRB2 CTRB1

7.30e-062622CID000281254
DrugN-acetyl-alpha-azaphenylalanine phenyl ester

CTRB2 CTRB1

7.30e-062622CID000191275
DrugAsp-Arg-Val-Tyr-Val-His-Pro-Phe-His-Leu

CTRB2 CTRB1

7.30e-062622CID004418081
Drugisobutyl sulfide

CTRB2 CTRB1

7.30e-062622CID000011607
Drugthiokynurenic acid

GRIA1 GRIN2A GRIN2B

8.55e-0615623CID003035667
DrugACEA-1011

GRIK3 GRIN2A GRIN2B

8.55e-0615623CID000127872
DrugChlorpyrifos

FZD1 FZD7 CLCN3 TENM3 CGRRF1 FZD5 APAF1 GRIA1 GRIK3 GRIN2A GRIN2B CTRB1

9.08e-069606212ctd:D004390
Drugmethylenecyclopropylglycine

GRIA1 GRIK3 GRIN2A GRIN2B

9.63e-0649624CID000441452
Drug5,7-dichlorokynurenic acid

GRIA1 GRIK3 GRIN2A GRIN2B

9.63e-0649624CID000001779
DrugAC1L1FA8

GRIA1 GRIK3 GRIN2A GRIN2B

1.05e-0550624CID000003150
DrugLY233536

GRIA1 GRIN2A GRIN2B

1.05e-0516623CID000126239
Drugaspartate

CLCN3 APAF1 GRIA1 GRIK3 GRIN2A GRIN2B FKBP8 COQ2 KYAT1

1.06e-05518629CID000000424
DrugLY354740

GRIA1 GRIK3 GRIN2A GRIN2B

1.13e-0551624CID000114827
Drugkynurenine

CD4 GRIA1 GRIN2A GRIN2B KYAT1

1.14e-05108625CID000000846
DrugQuinoxaline

GRIA1 GRIK3 GRIN2A GRIN2B

1.22e-0552624CID000007045
DrugAC1L1EKQ

GRIA1 GRIK3 GRIN2A GRIN2B

1.22e-0552624CID000002834
Drug7-Cl-Thio-Kyna

GRIA1 GRIN2A GRIN2B

1.27e-0517623CID003035668
Drugkazinol B

CTRB2 SLC5A8 CTRB1

1.27e-0517623CID000480869
DrugKainic Acid

JAK2 APAF1 GRIA1 GRIK3 GRIN2A GRIN2B

1.46e-05194626ctd:D007608
DrugMNQX

GRIA1 GRIN2A GRIN2B

1.52e-0518623CID000130818
Drug0317956-0000 [391210-11-0]; Up 200; 1uM; PC3; HT_HG-U133A

SLC44A1 CWH43 CLCN3 APAF1 SNX13 DNMT3A

1.69e-051996264334_UP
DrugDL-Serine

ERVK-6 CTRB2 GRIA1 GRIN2A GRIN2B CTRB1

1.89e-05203626CID000000617
DrugMPEP

GRIA1 GRIK3 GRIN2A GRIN2B

2.03e-0559624CID003025961
Drugibotenic acid

CLCN3 GRIA1 GRIK3 GRIN2A GRIN2B

2.06e-05122625CID000001233
Drugkynurenic acid

GRIA1 GRIK3 GRIN2A GRIN2B KYAT1

2.06e-05122625CID000003845
Drug3-amino-2-pyridone

CTRB2 CTRB1

2.18e-053622CID000322353
DrugASA-BMPA

CTRB2 CTRB1

2.18e-053622CID003035649
Drugp-nitrophenyl benzoate

CTRB2 CTRB1

2.18e-053622CID000070396
DrugN-acetylbenzotriazole

CTRB2 CTRB1

2.18e-053622CID000087784
DrugZ-Phe-OMe

CTRB2 CTRB1

2.18e-053622CID003082435
Drugphotophor

CTRB2 CTRB1

2.18e-053622CID000014780
Drug3-methylcoumarin

CTRB2 CTRB1

2.18e-053622CID000017130
Drugdibutyl iodomethaneboronate

CTRB2 CTRB1

2.18e-053622CID000098591
Drugzinc;dipicolinate

CTRB2 CTRB1

2.18e-053622CID004309911
Drug2-propyl methylphosphonochloridate

CTRB2 CTRB1

2.18e-053622CID000102124
Drug2-oxobut-3-ynoate

CTRB2 CTRB1

2.18e-053622CID000171547
DrugAFMeq

CTRB2 CTRB1

2.18e-053622CID000194069
DrugBz-Cti-otbu

CTRB2 CTRB1

2.18e-053622CID006452691
Drugn-(2-oxoethyl)benzamide

CTRB2 CTRB1

2.18e-053622CID000188995
DrugAC1L49DM

CTRB2 CTRB1

2.18e-053622CID000152933
DrugFK-316

CTRB2 CTRB1

2.18e-053622CID000133688
DrugAC1L19T8

CTRB2 CTRB1

2.18e-053622CID000000694
DrugMarinostatin D

CTRB2 CTRB1

2.18e-053622CID000132206
Drugc140

CTRB2 CTRB1

2.18e-053622CID002783250
Drugconotoxin GV

GRIN2A GRIN2B

2.18e-053622ctd:C055407
Drug1FD7

CTRB2 CTRB1

2.18e-053622CID000445579
DrugBenzamidomethaneboronic acid

CTRB2 CTRB1

2.18e-053622CID000127677
DrugFelbamate

GRIN2A GRIN2B

2.18e-053622DB00949
Drugphenyl hippurate

CTRB2 CTRB1

2.18e-053622CID000076323
DrugFK-386

CTRB2 CTRB1

2.18e-053622CID000135044
DrugFK-375

CTRB2 CTRB1

2.18e-053622CID000135042
Drugcarbostyril-124

CTRB2 CTRB1

2.18e-053622CID000088277
DrugN-trifluoroacetyl-4-fluorophenylalanine

CTRB2 CTRB1

2.18e-053622CID000328214
DrugGlt-leu-phe-nh-meq

CTRB2 CTRB1

2.18e-053622CID000194914
Diseasehyperhomocysteinemia (implicated_via_orthology)

GRIA1 GRIN2A GRIN2B

1.37e-0611613DOID:9279 (implicated_via_orthology)
Diseaselevel of chymotrypsinogen B2 in blood serum

CTRB2 CTRB1

4.20e-062612OBA_2041192
Diseasechymotrypsinogen B measurement

CTRB2 CTRB1

1.26e-053612EFO_0801477
Diseaseglycerol kinase deficiency (implicated_via_orthology)

GK GK2

1.26e-053612DOID:0060363 (implicated_via_orthology)
DiseaseMorphine Abuse

GRIA1 GRIN2A

8.77e-057612C0600272
DiseaseMorphine Dependence

GRIA1 GRIN2A

8.77e-057612C0026552
Diseaseplacental insufficiency (biomarker_via_orthology)

GRIN2A GRIN2B

1.17e-048612DOID:3891 (biomarker_via_orthology)
Diseasecognitive disorder (biomarker_via_orthology)

GRIN2A GRIN2B

1.17e-048612DOID:1561 (biomarker_via_orthology)
DiseaseAsthma, Occupational

TENM3 HERC2

1.87e-0410612C0264423
Diseasevascular dementia (is_marker_for)

GRIN2A GRIN2B

2.28e-0411612DOID:8725 (is_marker_for)
Diseasetrypsin-2 measurement

CTRB2 CTRB1

2.28e-0411612EFO_0008305
Diseaseschizophrenia (biomarker_via_orthology)

ERBB4 GRIN2B

4.34e-0415612DOID:5419 (biomarker_via_orthology)
DiseaseAcute myeloid leukemia

JAK2 DNMT3A

5.60e-0417612cv:C0023467
DiseaseLEUKEMIA, ACUTE MYELOID

JAK2 DNMT3A

5.60e-0417612601626
Diseaseepilepsy (biomarker_via_orthology)

GRIA1 GRIN2B

8.61e-0421612DOID:1826 (biomarker_via_orthology)
DiseaseHbA1c measurement, response to sulfonylurea

SLCO1B7 GRIN2A

8.61e-0421612EFO_0004541, EFO_0007922
DiseaseHuntington's disease (is_implicated_in)

GRIN2A GRIN2B

1.03e-0323612DOID:12858 (is_implicated_in)
Diseasenephrotic syndrome (implicated_via_orthology)

KIRREL2 COQ2

1.13e-0324612DOID:1184 (implicated_via_orthology)
Diseasestatus epilepticus (biomarker_via_orthology)

GRIA1 GRIN2A MFN1

1.18e-03100613DOID:1824 (biomarker_via_orthology)
Diseasediet measurement

ADH5 ERBB4 KCNQ5 GRIA1 GRIK3 TSPAN5 RSKR DNMT3A

1.38e-031049618EFO_0008111
Diseasebipolar disorder (is_implicated_in)

GRIN2A GRIN2B

1.65e-0329612DOID:3312 (is_implicated_in)
DiseaseMental Depression

GRIA1 GRIK3 GRIN2A GRIN2B

1.90e-03254614C0011570

Protein segments in the cluster

PeptideGeneStartEntry
WSFDGTVKVWNIITG

APAF1

1061

O14727
KDGAWTLVGIVSWGS

CTRB2

221

Q6GPI1
GLWVWVSLLVAAGTV

ERBB4

6

Q15303
GIGELVWGKLRGFSW

DNMT3A

291

Q9Y6K1
GRTWKGTAFGGWKSV

ADH5

311

P11766
GKLLATGIQWGTWTK

ANGPTL5

351

Q86XS5
GSLALGAVPTWTKLW

CIRBP-AS1

51

Q8TBR5
KWSFGTTLWEICSGG

JAK2

736

O60674
IVGGVIWKTIGWKLL

MFN1

601

Q8IWA4
LTFNWGALLGWSAIK

COQ2

211

Q96H96
GTIDSWLIWSLTGGV

GK3P

176

Q14409
FSLALTKSGVVWTWG

HERC2

3216

O95714
LVWKGQSSWGTGESF

LMNB2

546

Q03252
ALWWGTITLTTIGYG

KCNQ5

301

Q9NR82
RWSSVFWKVGLISGT

NRSN1

56

Q8IZ57
VGITSGFWIWSGKTL

FZD2

531

Q14332
KTWEIGKVITWGRGF

HERVK_113

821

P63132
WWSLGVLLFSLATGK

RSKR

286

Q96LW2
KTWEIGKVITWGRGF

ERVK-7

821

P63135
KTWEIGKVITWGRGF

ERVK-6

821

Q9BXR3
LIVGITSGFWIWSGK

FZD1

611

Q9UP38
LVGITSGMWIWSAKT

FZD4

486

Q9ULV1
LVVGITSGVWIWSGK

FZD5

511

Q13467
GITTGFWIWSGKTLQ

FZD7

541

O75084
VGITSGVWVWSGKTL

FZD8

596

Q9H461
IPWKWLFGATAVALG

FKBP8

386

Q14318
GTIDSWLIWSLTGGV

GK2

176

Q14410
WLKGLTQAFGGFLIW

GNPAT

411

O15228
SSWISWGVGVFLLKP

CHMP7

116

Q8WUX9
WIAGGTWTPSALKFA

COL6A2

696

P12110
AFTVEKLTGSGELWW

CD4

226

P01730
GTIDSWLIWSLTGGV

GK

176

P32189
IPKGVVSFKSGNWGW

MAN1C1

301

Q9NR34
WGLVQWTKSGLALGG

KIRREL2

51

Q6UWL6
GSLGGTGVLWWLYAK

SLC44A1

251

Q8WWI5
SGRIVGGVWWFFTLI

GRIA1

611

P42261
KALSTRIIGGIWWFF

GRIK3

631

Q13003
IVTTGLVLGWFGWDV

CGRRF1

26

Q99675
VGKWPWQVSILFLGT

PRSS46P

51

E5RG02
GWGFSGWISALVVPK

SCAMP3

256

O14828
KDGAWTLVGIVSWGS

CTRB1

221

P17538
TFSVTGWKLGWSIGP

KYAT3

281

Q6YP21
KGSDVWSFGVLLWEL

MAP3K11

301

Q16584
GLIWWVTGTASAAGL

CWH43

261

Q9H720
SLSIWGWGSLGIVLF

SNX13

6

Q9Y5W8
TALFTFGWTGTIWGI

SLC35G2

286

Q8TBE7
FGWTGTIWGISTMFI

SLC35G2

291

Q8TBE7
GKTFSATGWKVGWVL

KYAT1

246

Q16773
KWAWDSGLVLGTLIF

SLC9A5

356

Q14940
TFWTIIIGGTFTWTS

SLC5A8

241

Q8N695
WWLGFLVSGIVSIIS

SLCO1B7

211

G3V0H7
WGLLIILSVSSSWVG

SLC35F4

166

A4IF30
WTKWVFAGVSLVGLI

SLC28A2

146

O43868
WSGWLVVTLTGLASG

CLCN3

126

P51790
WVGGLILWLSVGSSG

PLA1A

11

Q53H76
NILSGASWVSWGLVK

SPART

426

Q8N0X7
ASWVSWGLVKGAEIT

SPART

431

Q8N0X7
WLKVGFTLGTTVFLW

NDUFC1

41

O43677
KTWEIGKVITWGRGF

ERVK-10

821

P10266
KTWEIGKVITWGRGF

ERVK-8

821

P63133
VSLLGTWIGKGTERW

UBE2O

1041

Q9C0C9
KTWEIGKVITWGRGF

ERVK-11

821

Q9UQG0
GGAQSWLWFATVKSL

TENM3

2481

Q9P273
WLWFATVKSLIGKGV

TENM3

2486

Q9P273
ITFLGIGLWAWNEKG

TSPAN5

31

P62079
WGVVITWSGIKGVFN

SLC9C2

371

Q5TAH2
TWSGIKGVFNLLWAP

SLC9C2

376

Q5TAH2
VVFLGVGLWAWSEKG

TSPAN14

31

Q8NG11
WWTITGGLGTVVSTL

SLC14A2

151

Q15849
GPSFTIGKAIWLLWG

GRIN2A

596

Q12879
GGPSFTIGKAIWLLW

GRIN2B

596

Q13224