Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	aspartic-type endopeptidase activity	ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19 ERVK-25 ERVK-24	1.22e-09	37	111	7	GO:0004190
GeneOntologyMolecularFunction	aspartic-type peptidase activity	ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19 ERVK-25 ERVK-24	1.48e-09	38	111	7	GO:0070001
GeneOntologyBiologicalProcess	nuclear-transcribed mRNA poly(A) tail shortening	PNLDC1 TNRC6C PABPC1 PABPC3	2.88e-05	33	111	4	GO:0000289
GeneOntologyBiologicalProcess	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	TNRC6C PABPC1 PABPC3	5.29e-05	14	111	3	GO:0060213
GeneOntologyBiologicalProcess	regulation of nuclear-transcribed mRNA poly(A) tail shortening	TNRC6C PABPC1 PABPC3	8.07e-05	16	111	3	GO:0060211
GeneOntologyBiologicalProcess	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	TNRC6C PABPC1 PABPC3	8.07e-05	16	111	3	GO:1900153
GeneOntologyBiologicalProcess	cell-cell fusion	ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19	9.60e-05	85	111	5	GO:0140253
GeneOntologyBiologicalProcess	syncytium formation by plasma membrane fusion	ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19	9.60e-05	85	111	5	GO:0000768
GeneOntologyBiologicalProcess	syncytium formation	ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19	1.19e-04	89	111	5	GO:0006949
Domain	PolyA	PABPC4 PABPC1 PABPC3	1.66e-06	5	104	3	SM00517
Domain	-	PABPC4 PABPC1 PABPC3	1.66e-06	5	104	3	1.10.1900.10
Domain	PABP	PABPC4 PABPC1 PABPC3	1.66e-06	5	104	3	PF00658
Domain	PABC	PABPC4 PABPC1 PABPC3	1.66e-06	5	104	3	PS51309
Domain	PABP_1234	PABPC4 PABPC1 PABPC3	1.66e-06	5	104	3	IPR006515
Domain	PABP_HYD	PABPC4 PABPC1 PABPC3	1.66e-06	5	104	3	IPR002004
Domain	-	TCERG1 PRPF40B	1.83e-04	4	104	2	1.10.10.440
Domain	RRM_dom_euk	PABPC4 PABPC1 PABPC3	2.74e-04	23	104	3	IPR003954
Domain	RRM_1	PABPC4 PABPC1 PABPC3	2.74e-04	23	104	3	SM00361
Domain	Anaphylatoxin_comp_syst	C4A C4B	3.04e-04	5	104	2	IPR018081
Domain	Anaphylatoxn_comp_syst_dom	C4A C4B	3.04e-04	5	104	2	IPR001840
Domain	FF	TCERG1 PRPF40B	4.54e-04	6	104	2	PF01846
Domain	FF	TCERG1 PRPF40B	4.54e-04	6	104	2	SM00441
Domain	FF_domain	TCERG1 PRPF40B	4.54e-04	6	104	2	IPR002713
Domain	FF	TCERG1 PRPF40B	4.54e-04	6	104	2	PS51676
Domain	ANATO	C4A C4B	6.33e-04	7	104	2	SM00104
Domain	ANATO	C4A C4B	6.33e-04	7	104	2	PF01821
Domain	ANAPHYLATOXIN_2	C4A C4B	6.33e-04	7	104	2	PS01178
Domain	ANAPHYLATOXIN_1	C4A C4B	6.33e-04	7	104	2	PS01177
Domain	Anaphylatoxin/fibulin	C4A C4B	6.33e-04	7	104	2	IPR000020
Domain	Thiol-ester_cl	C4A C4B	8.41e-04	8	104	2	PF10569
Domain	MacrogloblnA2_thiol-ester-bond	C4A C4B	8.41e-04	8	104	2	IPR019565
Domain	MacrogloblnA2_CS	C4A C4B	8.41e-04	8	104	2	IPR019742
Domain	RRM_1	U2SURP PABPC4 TNRC6C PABPC1 PABPC3 RBM15B	1.09e-03	208	104	6	PF00076
Domain	A2M_N	C4A C4B	1.34e-03	10	104	2	PF01835
Domain	A2M_N	C4A C4B	1.34e-03	10	104	2	IPR002890
Domain	A-macroglobulin_rcpt-bd	C4A C4B	1.34e-03	10	104	2	IPR009048
Domain	ALPHA_2_MACROGLOBULIN	C4A C4B	1.34e-03	10	104	2	PS00477
Domain	A2M	C4A C4B	1.34e-03	10	104	2	PF00207
Domain	A2M_N_2	C4A C4B	1.34e-03	10	104	2	IPR011625
Domain	A2M_comp	C4A C4B	1.34e-03	10	104	2	IPR011626
Domain	A2M_N_2	C4A C4B	1.34e-03	10	104	2	PF07703
Domain	A2M_recep	C4A C4B	1.34e-03	10	104	2	PF07677
Domain	A2M_comp	C4A C4B	1.34e-03	10	104	2	PF07678
Domain	Macroglobln_a2	C4A C4B	1.34e-03	10	104	2	IPR001599
Domain	RRM	U2SURP PABPC4 TNRC6C PABPC1 PABPC3 RBM15B	1.35e-03	217	104	6	SM00360
Domain	RRM_dom	U2SURP PABPC4 TNRC6C PABPC1 PABPC3 RBM15B	1.70e-03	227	104	6	IPR000504
Domain	RRM	U2SURP PABPC4 TNRC6C PABPC1 PABPC3 RBM15B	1.82e-03	230	104	6	PS50102
Domain	WW	TCERG1 PRPF40B ARHGAP12	2.28e-03	47	104	3	PF00397
Domain	WHTH_DNA-bd_dom	FOXK2 KAT6A GTF2IRD1 FOXR2 TFDP1 EIF3A	2.35e-03	242	104	6	IPR011991
Domain	WW	TCERG1 PRPF40B ARHGAP12	2.42e-03	48	104	3	SM00456
Domain	-	U2SURP PABPC4 TNRC6C PABPC1 PABPC3 RBM15B	2.44e-03	244	104	6	3.30.70.330
Domain	Ldl_recept_b	EGF LRP4	2.68e-03	14	104	2	PF00058
Domain	LDLRB	EGF LRP4	2.68e-03	14	104	2	PS51120
Domain	WW_DOMAIN_2	TCERG1 PRPF40B ARHGAP12	2.88e-03	51	104	3	PS50020
Domain	WW_DOMAIN_1	TCERG1 PRPF40B ARHGAP12	2.88e-03	51	104	3	PS01159
Domain	WW_dom	TCERG1 PRPF40B ARHGAP12	3.04e-03	52	104	3	IPR001202
Domain	LY	EGF LRP4	3.08e-03	15	104	2	SM00135
Domain	LDLR_classB_rpt	EGF LRP4	3.08e-03	15	104	2	IPR000033
Domain	Nucleotide-bd_a/b_plait	U2SURP PABPC4 TNRC6C PABPC1 PABPC3 RBM15B	3.22e-03	258	104	6	IPR012677
Domain	C345C	C4A C4B	3.95e-03	17	104	2	SM00643
Domain	Terpenoid_cyclase/PrenylTrfase	C4A C4B	4.43e-03	18	104	2	IPR008930
Domain	NTR	C4A C4B	4.94e-03	19	104	2	PF01759
Domain	Netrin_module_non-TIMP	C4A C4B	4.94e-03	19	104	2	IPR018933
Pubmed	Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.	ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19	2.58e-10	12	113	5	14557543
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	RALGAPA1 SYNRG CCDC8 SHROOM3 HIVEP1 ABL1 SORBS1 KIAA1191 PABPC1 FSIP2 PLEKHG1 TCERG1 RAB3GAP2 NAV2 NAV1 MACF1 PEAK1	2.89e-09	861	113	17	36931259
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SYNRG SHROOM3 FOXK2 ABL1 NLRX1 KAT6A ICE1 TNRC6C GTF2IRD1 BAHD1 PLEKHG1 SURF6 SBF2 NAV2 NAV1 LRP4 KCNQ2 WDFY3 ESPL1	2.98e-09	1105	113	19	35748872
Pubmed	A revised nomenclature for transcribed human endogenous retroviral loci.	ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19 ERVK-25 ERVK-24	2.57e-08	94	113	7	21542922
Pubmed	Nuclear relocalisation of cytoplasmic poly(A)-binding proteins PABP1 and PABP4 in response to UV irradiation reveals mRNA-dependent export of metazoan PABPs.	PABPC4 PABPC1 PABPC3	3.34e-08	3	113	3	21940797
Pubmed	Mapping of 12 markers in the proximal region of mouse chromosome 17 using recombinant t haplotypes.	HLA-B PIM1 C4A C4B	1.40e-07	15	113	4	7749235
Pubmed	Mouse lymphotoxin and tumor necrosis factor: structural analysis of the cloned genes, physical linkage, and chromosomal position.	HLA-B PIM1 C4A C4B	1.40e-07	15	113	4	2885372
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	RALGAPA1 DDX17 CALD1 PABPC4 SORBS1 PABPC1 PITPNM1 SLC44A1 SF3B1 PABPC3 NAV1 PPP1R18 KCNQ2 MACF1 C4A C4B EIF3A PEAK1 AGAP2	1.77e-07	1431	113	19	37142655
Pubmed	Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.	ERVK-21 ERVK-9 ERVK-25 ERVK-24	3.12e-07	18	113	4	18664271
Pubmed	Quantitation of HERV-K env gene expression and splicing in human breast cancer.	ERVK-6 ERVK-21 ERVK-19	3.32e-07	5	113	3	12629516
Pubmed	HIV- 1 protease inhibits Cap- and poly(A)-dependent translation upon eIF4GI and PABP cleavage.	PABPC4 PABPC1 PABPC3	3.32e-07	5	113	3	19956697
Pubmed	Embryonic Poly(A)-Binding Protein (EPAB) Is Required for Granulosa Cell EGF Signaling and Cumulus Expansion in Female Mice.	PABPC1 EGF PABPC3	3.32e-07	5	113	3	26492470
Pubmed	MKRN3-mediated ubiquitination of Poly(A)-binding proteins modulates the stability and translation of GNRH1 mRNA in mammalian puberty.	PABPC4 PABPC1 PABPC3	3.32e-07	5	113	3	33744966
Pubmed	Human MHC region harbors both susceptibility and protective haplotypes for coronary artery disease.	HLA-B C4A C4B	6.63e-07	6	113	3	17212707
Pubmed	Human endogenous retrovirus HERV-K(HML-2) proviruses with Rec protein coding capacity and transcriptional activity.	ERVK-6 ERVK-9 ERVK-19	6.63e-07	6	113	3	15063128
Pubmed	The eukaryotic polypeptide chain releasing factor (eRF3/GSPT) carrying the translation termination signal to the 3'-Poly(A) tail of mRNA. Direct association of erf3/GSPT with polyadenylate-binding protein.	PABPC4 PABPC1 PABPC3	6.63e-07	6	113	3	10358005
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	ELOA2 DDX17 CALD1 U2SURP PABPC4 JSRP1 PABPC1 ADAMTS12 SF3B1 GTF3C1 ZNF608 PABPC3 ARHGAP12 ANKRD30A NAV2 MACF1 EIF3A AGAP2	9.46e-07	1442	113	18	35575683
Pubmed	Linkage map of mouse chromosome 17: localization of 27 new DNA markers.	HLA-B PIM1 C4A C4B	1.07e-06	24	113	4	2574145
Pubmed	Chromosomal localization of three human poly(A)-binding protein genes and four related pseudogenes.	PABPC4 PABPC1 PABPC3	1.16e-06	7	113	3	10543404
Pubmed	The USP10-HDAC6 axis confers cisplatin resistance in non-small cell lung cancer lacking wild-type p53.	U2SURP PABPC4 PABPC1 SF3B1 EIF3A	1.44e-06	59	113	5	32382008
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	HIVEP1 DDX17 CALD1 U2SURP PABPC4 ICE1 BCOR PABPC1 SF3B1 TCERG1 PABPC3 SURF6 RBM15B PDS5A	2.75e-06	954	113	14	36373674
Pubmed	Aberrant splicing caused by the insertion of the B2 sequence into an intron of the complement C4 gene is the basis for low C4 production in H-2k mice.	HLA-B C4A C4B	2.77e-06	9	113	3	1373139
Pubmed	Control of Paip1-eukayrotic translation initiation factor 3 interaction by amino acids through S6 kinase.	PABPC1 PABPC3 EIF3A	2.77e-06	9	113	3	24396066
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	RALGAPA1 DDX17 CALD1 PABPC4 PABPC1 C1orf198 TCERG1 RAB3GAP2 ARHGAP12 MACF1 PDS5A PEAK1	3.50e-06	708	113	12	39231216
Pubmed	Granzyme B proteolyzes receptors important to proliferation and survival, tipping the balance toward apoptosis.	ABL1 PABPC1 PABPC3	3.94e-06	10	113	3	16798735
Pubmed	HLA-association of serum levels of natural antibodies.	HLA-B C4A C4B	3.94e-06	10	113	3	19167759
Pubmed	Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.	ERVK-6 ERVK-21 ERVK-19	3.94e-06	10	113	3	12970426
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	U2SURP SORBS1 BAHD1 NAV1 LRP4 MACF1	4.42e-06	130	113	6	12421765
Pubmed	A human MAP kinase interactome.	HIVEP1 HLA-B SORBS1 SF3B1 TCERG1 NAV2 NAV1 MACF1 C4A EIF3A	4.45e-06	486	113	10	20936779
Pubmed	miRNA repression involves GW182-mediated recruitment of CCR4-NOT through conserved W-containing motifs.	PABPC4 TNRC6C PABPC1	5.41e-06	11	113	3	21984184
Pubmed	The UbL protein UBTD1 stably interacts with the UBE2D family of E2 ubiquitin conjugating enzymes.	SHROOM3 BCOR UBTD1	7.19e-06	12	113	3	24211586
Pubmed	Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks.	DDX17 U2SURP PABPC4 PABPC1 SF3B1 PABPC3 EIF3A	8.06e-06	220	113	7	24550385
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	RALGAPA1 SHROOM3 SRRM4 ICE1 BCOR BAHD1 ZNF608 NAV2 LRP4 ESPL1	9.32e-06	529	113	10	14621295
Pubmed	Mapping of the L-methylmalonyl-CoA mutase gene to mouse chromosome 17.	HLA-B C4A C4B	9.33e-06	13	113	3	1970332
Pubmed	The arginine methyltransferase CARM1 regulates the coupling of transcription and mRNA processing.	PABPC1 TCERG1 PABPC3	9.33e-06	13	113	3	17218272
Pubmed	Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration.	CALD1 HLA-B PLEKHG1 NAV1 LRP4 C4A C4B	9.33e-06	225	113	7	23341629
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	HIVEP1 RUSC1 ICE1 BCOR TFDP1 GTF3C1 ZNF608 RAB3GAP2 NAV1	9.53e-06	418	113	9	34709266
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	RALGAPA1 GPRASP1 HIVEP1 BTBD10 UBXN6 RUSC1 KIAA1191 PABPC1 PITPNM1 C1orf198 EGF NECAB3 TEDC1	1.01e-05	925	113	13	28986522
Pubmed	Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.	C4A C4B	1.05e-05	2	113	2	22737222
Pubmed	Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.	C4A C4B	1.05e-05	2	113	2	16565498
Pubmed	Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.	C4A C4B	1.05e-05	2	113	2	15998580
Pubmed	Characterization of two cytoplasmic poly(A)-binding proteins, PABPC1 and PABPC2, in mouse spermatogenic cells.	PABPC1 PABPC3	1.05e-05	2	113	2	19020299
Pubmed	Structural polymorphism of murine C4 and its linkage to H-2.	C4A C4B	1.05e-05	2	113	2	7373044
Pubmed	High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.	C4A C4B	1.05e-05	2	113	2	19062096
Pubmed	The chemical structure of the C4d fragment of the human complement component C4.	C4A C4B	1.05e-05	2	113	2	3696167
Pubmed	Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.	C4A C4B	1.05e-05	2	113	2	1357031
Pubmed	Structural comparison of human C4A3 and C4B1 after proteolytic activation by C1s.	C4A C4B	1.05e-05	2	113	2	16098595
Pubmed	Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.	C4A C4B	1.05e-05	2	113	2	19933335
Pubmed	Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.	C4A C4B	1.05e-05	2	113	2	2459207
Pubmed	Antigen-induced B cell apoptosis is independent of complement C4.	C4A C4B	1.05e-05	2	113	2	17645767
Pubmed	Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpura.	C4A C4B	1.05e-05	2	113	2	15787745
Pubmed	Anti-DNA autoreactivity in C4-deficient mice.	C4A C4B	1.05e-05	2	113	2	12207352
Pubmed	Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.	C4A C4B	1.05e-05	2	113	2	30026462
Pubmed	A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B.	C4A C4B	1.05e-05	2	113	2	6559257
Pubmed	Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.	C4A C4B	1.05e-05	2	113	2	27758680
Pubmed	Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.	C4A C4B	1.05e-05	2	113	2	22387014
Pubmed	Complement C4 Is Reduced in iPSC-Derived Astrocytes of Autism Spectrum Disorder Subjects.	C4A C4B	1.05e-05	2	113	2	34299197
Pubmed	Assessment of complement C4 gene copy number using the paralog ratio test.	C4A C4B	1.05e-05	2	113	2	20506482
Pubmed	Polymerase chain reaction based C4AQ0 and C4BQ0 genotyping: association with systemic lupus erythematosus in southwest Han Chinese.	C4A C4B	1.05e-05	2	113	2	12480675
Pubmed	Low C4, C4A and C4B gene copy numbers are stronger risk factors for juvenile-onset than for adult-onset systemic lupus erythematosus.	C4A C4B	1.05e-05	2	113	2	26800705
Pubmed	Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.	C4A C4B	1.05e-05	2	113	2	23749435
Pubmed	Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.	C4A C4B	1.05e-05	2	113	2	23918728
Pubmed	Murine complement C4 is not required for experimental autoimmune encephalomyelitis.	C4A C4B	1.05e-05	2	113	2	15390104
Pubmed	Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.	C4A C4B	1.05e-05	2	113	2	3037333
Pubmed	Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.	C4A C4B	1.05e-05	2	113	2	11726230
Pubmed	Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.	C4A C4B	1.05e-05	2	113	2	4216347
Pubmed	Functional compensation for the loss of testis-specific poly(A)-binding protein, PABPC2, during mouse spermatogenesis.	PABPC1 PABPC3	1.05e-05	2	113	2	26971890
Pubmed	Importance of the alpha 3-fragment of complement C4 for the binding with C4b-binding protein.	C4A C4B	1.05e-05	2	113	2	1699796
Pubmed	Structural insights into the human GW182-PABC interaction in microRNA-mediated deadenylation.	TNRC6C PABPC1	1.05e-05	2	113	2	20098421
Pubmed	Sequence determination of the thiolester site of the fourth component of human complement.	C4A C4B	1.05e-05	2	113	2	6950384
Pubmed	Molecular cloning and characterization of complementary and genomic DNA clones for mouse C4 and Slp.	C4A C4B	1.05e-05	2	113	2	2997024
Pubmed	Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.	C4A C4B	1.05e-05	2	113	2	8660986
Pubmed	Constitutive expression of Slp genes in mouse strain B10.WR directed by C4 regulatory sequences.	C4A C4B	1.05e-05	2	113	2	3624865
Pubmed	Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.	C4A C4B	1.05e-05	2	113	2	8428773
Pubmed	Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.	ERVK-6 ERVK-19	1.05e-05	2	113	2	9060628
Pubmed	Determination of the loss of function complement C4 exon 29 CT insertion using a novel paralog-specific assay in healthy UK and Spanish populations.	C4A C4B	1.05e-05	2	113	2	21857912
Pubmed	Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.	C4A C4B	1.05e-05	2	113	2	24638111
Pubmed	Isolation of cDNA clones specifying the fourth component of mouse complement and its isotype, sex-limited protein.	C4A C4B	1.05e-05	2	113	2	6208559
Pubmed	The role of the histocompatibility-2-linked Ss-Slp region in the control of mouse complement.	C4A C4B	1.05e-05	2	113	2	4514997
Pubmed	Transcriptional repression of C4 complement by hepatitis C virus proteins.	C4A C4B	1.05e-05	2	113	2	21345967
Pubmed	The inheritance of susceptibility to the Gross leukemia virus in mice.	C4A C4B	1.05e-05	2	113	2	5919331
Pubmed	An ancient provirus has imposed androgen regulation on the adjacent mouse sex-limited protein gene.	C4A C4B	1.05e-05	2	113	2	3167981
Pubmed	Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.	ERVK-6 ERVK-19	1.05e-05	2	113	2	9460924
Pubmed	The dichotomous size variation of human complement C4 genes is mediated by a novel family of endogenous retroviruses, which also establishes species-specific genomic patterns among Old World primates.	C4A C4B	1.05e-05	2	113	2	7545960
Pubmed	Insights on the relationship between complement component C4 serum concentrations and C4 gene copy numbers in a Western Australian systemic lupus erythematosus cohort.	C4A C4B	1.05e-05	2	113	2	30041577
Pubmed	Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.	C4A C4B	1.05e-05	2	113	2	2572548
Pubmed	The complement component C4 of mammals.	C4A C4B	1.05e-05	2	113	2	2302180
Pubmed	Complete cDNA sequence of the fourth component of murine complement.	C4A C4B	1.05e-05	2	113	2	3862104
Pubmed	The BS variant of C4 protects against age-related loss of white matter microstructural integrity.	C4A C4B	1.05e-05	2	113	2	34358307
Pubmed	Acute renal allograft rejection: diagnostic significance of focal peritubular capillary C4d.	C4A C4B	1.05e-05	2	113	2	18360261
Pubmed	Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.	C4A C4B	1.05e-05	2	113	2	22151770
Pubmed	C4d-positive chronic rejection: a frequent entity with a poor outcome.	C4A C4B	1.05e-05	2	113	2	18091514
Pubmed	Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.	C4A C4B	1.05e-05	2	113	2	29080553
Pubmed	Levels of free PABP are limited by newly polyadenylated mRNA in early Spisula embryogenesis.	PABPC1 PABPC3	1.05e-05	2	113	2	10954604
Pubmed	Schizophrenia risk from complex variation of complement component 4.	C4A C4B	1.05e-05	2	113	2	26814963
Pubmed	Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.	C4A C4B	1.05e-05	2	113	2	6589636
Pubmed	C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.	C4A C4B	1.05e-05	2	113	2	25339671
Pubmed	A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.	C4A C4B	1.05e-05	2	113	2	17728371
Pubmed	Structure and organization of the C4 genes.	C4A C4B	1.05e-05	2	113	2	6149580
Pubmed	Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.	C4A C4B	1.05e-05	2	113	2	6149581
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	C4A C4B	3.59e-04	9	58	2	1234
GeneFamily	RNA binding motif containing	U2SURP PABPC4 PABPC1 PABPC3 RBM15B	5.97e-04	213	58	5	725
GeneFamily	NLR family	NLRX1 NAIP	2.89e-03	25	58	2	666
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PLEKHG1 SBF2 ARHGAP12 AGAP2	4.30e-03	206	58	4	682
GeneFamily	Complement system\|Sushi domain containing	C4A C4B	5.94e-03	36	58	2	492
GeneFamily	Glycosyltransferase family 6\|Blood group antigens	C4A C4B	6.27e-03	37	58	2	454
GeneFamily	Potassium voltage-gated channels	KCNG3 KCNQ2	7.30e-03	40	58	2	274
GeneFamily	Ankyrin repeat domain containing	ANKRD62 BCOR ANKRD30A AGAP2	7.55e-03	242	58	4	403
GeneFamily	Forkhead boxes	FOXK2 FOXR2	8.39e-03	43	58	2	508
ToppCell	LA-06._Ventricular_Cardiomyocyte_II\|LA / Chamber and Cluster_Paper	CALD1 AVPR2 SORBS1 LRRC25 FDXR	2.76e-06	92	106	5	fad2e02ae858e3a9bbe51ad1c689f7e31d11ce0e
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6-Excitatory_Neuron.Slc17a7.Bcl6-Ptgfr_(Postsubiculum)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	PNLDC1 KCNG3 FOXR2 C4A TEDC1	3.77e-06	98	106	5	9865a9de11dea6db0b75dd04fee523cd2da44766
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SHROOM3 GTF2IRD1 C1orf198 PTPRQ NAV2 ZC3H12C	5.75e-06	187	106	6	d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCell	PND01-03-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	ADAMTS12 C1orf198 NAV2 LRP4 MACF1 PEAK1	6.49e-06	191	106	6	e7c605b56934d1383237c1f946dbccef25d91368
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	RALGAPA1 SYNRG BCOR SBF2 PDS5A WDFY3	6.89e-06	193	106	6	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	systemic_lupus_erythematosus-flare\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SAMD9 DDX17 PABPC1 SF3B1 PIM1 MACF1	7.97e-06	198	106	6	4c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCell	BLOOD--(0)_NK_cell-(0)_NK_cells_(CD56dim-like)\|(0)_NK_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	HLA-B TMEM71 GTF3C1 PIM1 PPP1R18	2.53e-05	145	106	5	6dd81d53d006fcc206a10969374a11c372f92133
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CARMIL3 TNS2 SORCS1 FSIP2 NAV1	3.48e-05	155	106	5	77fdae85d36efb776db977eb424b32487ef222e4
ToppCell	Adult-Immune-mast_cell-D175\|Adult / Lineage, Cell type, age group and donor	DCTD TFDP1 KRBA1 NAV1 AGAP2	3.93e-05	159	106	5	9f53fe2e0f25448d62a591c8e528e9a49b5400d5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 FNDC1 C1orf198 NAV2 AGAP2	4.17e-05	161	106	5	a7e09cf2ca6cd70d40d08440fe9c5ab9befa1b79
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GLDN APOBR TMEM71 SORCS1 C1orf198	4.17e-05	161	106	5	7d1bc73f4c82465b3f489d6737048b0cd54f22cf
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GLDN APOBR TMEM71 SORCS1 C1orf198	4.17e-05	161	106	5	410eef62c83c704cbfc5a1b643c4db11bbdcd81f
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Neural\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GLDN APOBR TMEM71 SORCS1 C1orf198	4.17e-05	161	106	5	71022485da6754a2b57b4c3e758e3de4c95cc292
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Neural-neural_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GLDN APOBR TMEM71 SORCS1 C1orf198	4.17e-05	161	106	5	59ae8a7c9a04ecaa335b8064852a5a91a21780bd
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 FNDC1 C1orf198 NAV2 AGAP2	4.17e-05	161	106	5	08920a716f6ec62538e361211455a30ad726d7be
ToppCell	390C-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	RAB9B SHROOM3 SIDT1 ICE1 TMEM71	4.30e-05	162	106	5	45be019b50e3727fc9d3fad2ff78e74e4f2d746b
ToppCell	390C-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	RAB9B SHROOM3 SIDT1 ICE1 TMEM71	4.30e-05	162	106	5	fbb0cc2b1434a340dc35058b77c73ea61004c252
ToppCell	facs-Pancreas-Exocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RALGAPA1 CARMIL3 BTBD10 C1orf198 PIM1	4.56e-05	164	106	5	b895674ed2df87db8fbfb30b7e31620945588491
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RAB9B CALD1 ADAMTS12 C4B TEDC1	4.97e-05	167	106	5	784776d1fcc098f84d3c2eca58fa56cb9428f434
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l44-58\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PNLDC1 LRRC30 JSRP1 PTPRQ ART5	4.97e-05	167	106	5	d78356bf0c473816dbabaee51984940bd822f84e
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-8\|TCGA-Thryoid / Sample_Type by Project: Shred V9	GLDN HIVEP1 PLEKHG1 NAV2 LRP4	5.11e-05	168	106	5	00646601548b0fee42ae16bfa5e93603bc7c5129
ToppCell	facs-Heart-RV-18m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SRRM4 FOXR2 FNDC1 LRP4 FLACC1	5.41e-05	170	106	5	d7c9a604311974ff87ece43a0f8725a234d262f7
ToppCell	LA-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	CALD1 AVPR2 LRRC25 FDXR	5.83e-05	88	106	4	7232b13a9788f89600411222c0d93bdc3788816f
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SHROOM3 C1orf198 PTPRQ NAV2 ZC3H12C	6.90e-05	179	106	5	4f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SRRM4 SORCS1 PTPRQ KCNQ2 ZNF488	7.86e-05	184	106	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KAT6A ZNF608 MACF1 PDS5A EIF3A	7.86e-05	184	106	5	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	HIVEP1 CALD1 SORBS1 PLEKHG1 MACF1	7.86e-05	184	106	5	d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SRRM4 SORCS1 PTPRQ KCNQ2 ZNF488	7.86e-05	184	106	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SRRM4 SORCS1 PTPRQ KCNQ2 ZNF488	7.86e-05	184	106	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D175\|Adult / Lineage, Cell type, age group and donor	SHROOM3 PTPRQ SCNN1G ZC3H12C PEAK1	8.06e-05	185	106	5	32b4e68e551d435a732f253f6ad83408c759a642
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CALD1 SORCS1 ADAMTS12 FNDC1 LRP4	8.06e-05	185	106	5	3b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCell	IPF-Lymphoid-B_Plasma\|Lymphoid / Disease state, Lineage and Cell class	JSRP1 SLC44A1 ZNF608 C4A C4B	8.27e-05	186	106	5	f9c21daf905d0bb0e0e769ca4bb069ea4b1ba25b
ToppCell	Epithelial-alveolar_epithelial_cell_type_1\|World / Lineage, Cell type, age group and donor	SHROOM3 C1orf198 PTPRQ NAV2 ZC3H12C	8.27e-05	186	106	5	09d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HLA-B SIDT1 NAIP LRRC25 SAT1	8.27e-05	186	106	5	c0a58e43a813441d3a1708236737b15db8bea10e
ToppCell	COVID-19-kidney-DCT\|kidney / Disease (COVID-19 only), tissue and cell type	SHROOM3 GTF2IRD1 EGF SAT1 NAV2	8.70e-05	188	106	5	df1fd0819d301679f3c9ea404e942e39095912eb
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CALD1 KAT6A NAV1 MACF1 EIF3A	9.14e-05	190	106	5	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SHROOM3 CALD1 LRP4 MACF1 C4B	9.37e-05	191	106	5	44a9a6768084dafc641ad455b65862bfd4cc0cb9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CALD1 SORBS1 ADAMTS12 FNDC1 NAV2	9.37e-05	191	106	5	39092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CALD1 SORBS1 ADAMTS12 FNDC1 NAV2	9.37e-05	191	106	5	ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCell	Epithelial-club_cell\|World / Lineage, Cell type, age group and donor	SHROOM3 PLEKHG1 ZNF608 NAV2 SCNN1G	9.84e-05	193	106	5	2bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCell	Control-Endothelial-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KAT6A SORBS1 PLEKHG1 SBF2 ZC3H12C	9.84e-05	193	106	5	aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCell	Control-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KAT6A SORBS1 PLEKHG1 SBF2 ZC3H12C	9.84e-05	193	106	5	c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCell	COVID_non-vent-Lymphocytic-T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	GPRASP1 DDX17 KAT6A TNRC6C MACF1	1.03e-04	195	106	5	4bdedd924564a260841a9153604026b57487c83d
ToppCell	PND01-03-samps-Mesenchymal-Matrix_fibroblast\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	GTF3C1 NAV2 LRP4 MACF1 PEAK1	1.06e-04	196	106	5	54f4cf778f95a9ff662e5c7520916a25e605bf95
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CALD1 SORBS1 ADAMTS12 FNDC1 C1orf198	1.06e-04	196	106	5	fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CALD1 SORBS1 ADAMTS12 FNDC1 C1orf198	1.06e-04	196	106	5	802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCell	PBMC-Control-cDC_3\|Control / Compartment, Disease Groups and Clusters	DDX17 APOBR PABPC1 PABPC3 NAV1	1.06e-04	196	106	5	09d197b321ff9f13c0672ea059c850845b0dbbd5
ToppCell	3'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HLA-B SIDT1 NAIP LRRC25 SAT1	1.08e-04	197	106	5	759f26753f76af3ae8d8527c4d221206245a3d45
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CALD1 SORBS1 ADAMTS12 NAV2 PEAK1	1.08e-04	197	106	5	85a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CALD1 SORBS1 ADAMTS12 NAV2 PEAK1	1.08e-04	197	106	5	e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCell	10x3'2.3-week_17-19-Mesenchymal_adipo\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	GLDN CALD1 TNS2 FNDC1 NAV2	1.08e-04	197	106	5	5afddde4e2b5cd55abe11e9b9efae02dbdc3da3a
ToppCell	10x3'2.3-week_17-19-Mesenchymal_adipo-stroma-adipo-CAR\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	GLDN CALD1 TNS2 FNDC1 NAV2	1.08e-04	197	106	5	1baffd087ca194a7355fefbb3bf67befb14fe2de
ToppCell	10x3'2.3-week_17-19-Mesenchymal_adipo-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	GLDN CALD1 TNS2 FNDC1 NAV2	1.08e-04	197	106	5	b9745e382baa2725dfcae060701fb53f6c8a31fa
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HLA-B NAIP APOBR LRRC25 SAT1	1.11e-04	198	106	5	79c8ab15e73f727c5e110ab9eab3ccb5edf9f714
ToppCell	stromal_cell\|World / Lineage and Cell class	GLDN CALD1 TNS2 FNDC1 NAV2	1.14e-04	199	106	5	507a82d0529b5b1fa5aebcfe43db53f0b6e3f8f0
ToppCell	stromal_cell-stromal_cell\|World / Lineage and Cell class	GLDN CALD1 TNS2 FNDC1 NAV2	1.14e-04	199	106	5	74262363a34da3a1eb55ab375fd61ddd7bb39b23
ToppCell	COPD-Myeloid-Macrophage\|Myeloid / Disease state, Lineage and Cell class	NRDE2 PABPC4 GTF2IRD1 SLC44A1 ZC3H12C	1.14e-04	199	106	5	1cf1b2d6debf9e3389f1829dcaa2857e9533a080
ToppCell	(03)_KRT6B+\|World / shred by cell type by condition	CALD1 HLA-B PIM1 NAV2 PPP1R18	1.14e-04	199	106	5	9feaf8649b3f68f30b8cb6b045a2caa2dd343c7f
ToppCell	distal-Hematologic-Classical_Monocyte-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NAIP TMEM71 PABPC1 LRRC25 SAT1	1.14e-04	199	106	5	bd8519da7a90f0b90626b86c6be0d62248a0a24a
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|Control_saline / Treatment groups by lineage, cell group, cell type	CALD1 SORCS1 ADAMTS12 FNDC1 LRP4	1.16e-04	200	106	5	a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SAMD9 DDX17 SF3B1 MACF1 EIF3A	1.16e-04	200	106	5	12f1685ce8f218433068e090c9d839cd5a1910bf
Computational	Neighborhood of MAP4K4	RALGAPA1 DDX17 TNS2 C1orf198 LRP4 MACF1 PEAK1	7.58e-05	172	65	7	GCM_MAP4K4
Disease	Syndactyly	ABL1 LRP4	3.20e-04	8	101	2	C0039075
Disease	Graves' disease (is_implicated_in)	HLA-B C4A C4B	3.25e-04	39	101	3	DOID:12361 (is_implicated_in)
Disease	cholesterol:total lipids ratio, intermediate density lipoprotein measurement	SHROOM3 HLA-B LRP4 MACF1	8.08e-04	121	101	4	EFO_0008595, EFO_0020943
Disease	alcohol and nicotine codependence	HIVEP1 PLEKHG1	8.83e-04	13	101	2	EFO_0004776
Disease	triglycerides:total lipids ratio, intermediate density lipoprotein measurement	SHROOM3 HLA-B LRP4 MACF1	9.68e-04	127	101	4	EFO_0008595, EFO_0020947
Disease	serum albumin measurement	SHROOM3 HIVEP1 HLA-B PABPC4 LRRC25 SBF2 MACF1 TEDC1	9.88e-04	592	101	8	EFO_0004535
Disease	revision of total hip arthroplasty	ICE1 ADAMTS12	1.03e-03	14	101	2	EFO_0020973
Disease	receptive language perception, parental genotype effect measurement	PLEKHG1 SCNN1G	1.03e-03	14	101	2	EFO_0005686, EFO_0005939
Disease	Malignant neoplasm of breast	ABL1 AVPR2 SORBS1 PABPC1 SORCS1 EGF PIM1 ANKRD30A MACF1 FLACC1 AGAP2	1.13e-03	1074	101	11	C0006142
Disease	Dermatitis	HLA-B EGF	1.35e-03	16	101	2	C0011603
Disease	Bronchiectasis	DNAL1 SCNN1G	2.56e-03	22	101	2	C0006267
Disease	pulmonary arterial hypertension	PIM1 C12orf42	2.56e-03	22	101	2	EFO_0001361
Disease	Morbilliform Drug Reaction	HLA-B C4B	2.80e-03	23	101	2	C0406537
Disease	Drug Eruptions	HLA-B C4B	2.80e-03	23	101	2	C0011609
Disease	Behcet Syndrome	HLA-B C4A	3.05e-03	24	101	2	C0004943

Protein segments in the cluster

Peptide	Gene	Start	Entry
RLDSFKDWPRESAVG	NAIP	281	Q13075
NSSDPENWDRKLHSR	BTBD10	11	Q9BSF8
IWSGNQTLETRDRKP	ERVK-19	351	O71037
IWSGNQTLETRDRKP	ERVK-8	351	Q902F8
WSGNQTLETRDRKPF	ERVK-9	351	Q9UKH3
DGDQWTLSRKRLSCP	C4B	656	P0C0L5
SSRGVRPVSFSDWEK	FDXR	446	P22570
ETSEKFTWAAKGRPR	ANKRD30A	401	Q9BXX3
ATWRKNRDKDGFSNP	ANKRD62	16	A6NC57
WESDTRGRAKPSRDS	AGAP2	1011	Q99490
GTWIRESANKSDDRI	GLDN	321	Q6ZMI3
RAEAKGNRSWSEESL	BCOR	1261	Q6W2J9
TSSRRKRDLDGSEDW	ADAMTS12	76	P58397
RDRTFLEGDWTSPSK	RBM15B	541	Q8NDT2
LEGDWTSPSKSSDRR	RBM15B	546	Q8NDT2
GSKDSDLATQNRPLW	PDS5A	311	Q29RF7
WDTAGQERFKSLRTP	RAB9B	61	Q9NP90
WSQRDPSLRKSGVGN	PABPC1	86	P11940
STLPDWRNAAADNRS	KCNG3	191	Q8TAE7
SGALRRDPSKSTDWE	RAB3GAP2	31	Q9H2M9
WSQRDPSLRKSGVGN	PABPC4	86	Q13310
PSWASARDRQPSDFK	ELOA2	266	Q8IYF1
RAEPRNWTADKEGLR	KRBA1	531	A5PL33
WARDSRDAEPRKKQA	JSRP1	291	Q96MG2
WESEIPDKGRFSRTN	FLACC1	111	Q96Q35
NKLLRTSAPGDWESG	SBF2	766	Q86WG5
RSQEEPGKGSFWRID	FOXK2	321	Q01167
ARSRELNKPWAAQDG	LRRC25	196	Q8N386
QAWQKRRSSDDAGPG	CARMIL3	1186	Q8ND23
ETNADWDGRPTKRSS	FSIP2	451	Q5CZC0
WKINAERSRGEGPEA	C1orf198	191	Q9H425
PKSWSFGDRSRARQA	KCNQ2	481	O43526
ADPIITRWKRDSSGN	NUDT9	171	Q9BW91
SEGSRRAADAKPKRW	PEAK1	911	Q9H792
ARRRSLDKWQDEGSS	ONECUT1	436	Q9UBC0
GGSSRKELDWLSNPS	NRDE2	16	Q9H7Z3
PWRAREGLDKLVSDA	MACF1	1761	O94854
EDSRGATLNPWRKAQ	NLRX1	941	Q86UT6
DRNLSDKWSLFGPRS	KIAA1191	216	Q96A73
ETRPAGDRTFQKWAA	HLA-B	256	P01889
WSQRDPSLRKSGVGN	PABPC3	86	Q9H361
PRWTRDASISKGDFQ	ARHGAP12	296	Q8IWW6
SSTDADLPWNRAKNR	PTPRQ	2051	Q9UMZ3
KRGNRKSSTSDWPTD	KAT6A	441	Q92794
SAEAWLAEEPKRRGT	ESPL1	1406	Q14674
EAWRREASKSVPSAI	ICE1	2236	Q9Y2F5
SSLSRKDSRWGDRDS	EIF3A	881	Q14152
WSGNQTLETRDRKPF	ERVK-24	241	P61566
IWSGNQTLETRDRKP	ERVK-25	351	P61570
IWSGNQTLETRDRKP	ERVK-6	351	Q69384
WTDRGKSLIGRSDLN	EGF	571	P01133
SDDVLPWRRTAENKL	DCTD	61	P32321
VRSSDDRLSVAWKAP	FNDC1	166	Q4ZHG4
ERDGKWSTSVFQRTP	FNDC1	341	Q4ZHG4
ARWNSKENLLAGPSE	ABL1	46	P00519
DRDRATGGWSSSKKR	BAHD1	156	Q8TBE0
AKWRKTERGASDQEP	DRGX	86	A6NNA5
WSGNQTLETRDRKPF	ERVK-21	351	P61565
SLKDEDNARPRSCLW	FOXR2	256	Q6PJQ5
AQSSKREWKPLEDRS	SLC44A1	11	Q8WWI5
IWSGNQTLETRDRKP	HERVK_113	351	Q902F9
ERDWVLNEFRSGKAP	DDX17	456	Q92841
LARWEEKTGQRPSEA	DNAL1	11	Q4LDG9
GPDRWNSAFTRKDEI	GTF2IRD1	16	Q9UHL9
EDNLGPQLSKADRWR	CCDC8	181	Q9H0W5
LNSGKAREWTPRDIE	PPP1R18	336	Q6NYC8
FPESRKRREAESWNS	SCNN1G	131	P51170
DGDQWTLSRKRLSCP	C4A	656	P0C0L4
TGRRQKFSPWDDALL	LRRC30	21	A6NM36
GTSKWRRERPESCDD	NAV1	496	Q8NEY1
KDRISDWGELPNGTR	PIM1	71	P11309
RDKTNTWSGPREDPN	GPRASP1	266	Q5JY77
ENENGALKSRRPSSW	RUSC1	796	Q9BVN2
PRSERKNDNGTEAWG	TNRC6C	466	Q9HCJ0
SPSEDNWLKGTRRLD	TMEM71	141	Q6P5X7
WSDRDDATQGRKLSP	SYNRG	896	Q9UMZ2
KPFDPSSWQRERASD	SAMD9	506	Q5K651
TGNWRVRSSPDKDQI	PNLDC1	136	Q8NA58
EPGSKWRRNPSDVSD	NAV2	1026	Q8IVL1
WQAGEDKRSSRLSEP	SHROOM3	611	Q8TF72
KRRGASDLSSEEGWR	SAT1	141	P21673
RRPEAAKEEAAWASS	SURF6	81	O75683
QAVLPSWDKTERARD	HERC2P3	791	Q9BVR0
LQGDSPTKWRTEDFR	U2SURP	481	O15042
DLRPGDVSSKRNLWE	CALD1	766	Q05682
RAEFSAGAWSEPRKR	ARL6IP6	56	Q8N6S5
ASEAFPGAWENRTRK	APOBR	616	Q0VD83
ALGWSREDRPRQNSK	CIPC	66	Q9C0C6
EERARGAPKQAWNSS	C12orf42	151	Q96LP6
KTGRGPLSDDWARTA	PITPNM1	166	O00562
DSSPWSAGKRNRKGE	TFDP1	96	Q14186
ARLEQKQSRAWGPTS	UBXN6	61	Q9BZV1
WPSGARSEQRSAFSK	ZNF488	151	Q96MN9
SRRWSDQLSLDEKDG	WDFY3	3331	Q8IZQ1
SVDKSFSRGWSRDQP	RALGAPA1	711	Q6GYQ0
NARTRESAWTKPDGV	TCERG1	151	O14776
SSARKNRWDETPKTE	SF3B1	286	O75533
SSWEGTPAESREKNR	SIDT1	766	Q9NXL6
RAKFDRPEATSALWQ	TEDC1	41	Q86SX3
FSSQSKRQPWREESG	SORBS1	1111	Q9BX66
PLGTNSWERDKTCRE	SRRM4	71	A7MD48
PERSGLSWSNREKAK	PRPF40B	266	Q6NWY9
QLRSKRDEFWDTAPA	UBTD1	46	Q9HAC8
KGSQRSWPETADRIF	ZACN	356	Q401N2
NWKDSRGTRVAVSSP	ZNF608	1321	Q9ULD9
KDGWASPQESSLLRS	PLEKHG1	1056	Q9ULL1
AWRKEQSRPDALITD	ZC3H12C	291	Q9C0D7
KDRGEWDSLTPEARR	UBE4A	816	Q14139
SPRGTKRRASWASEN	GTF3C1	1856	Q12789
KRRASWASENGETDA	GTF3C1	1861	Q12789
NKGRDWRLLQAPDTD	SORCS1	496	Q8WY21
SELRRWRSEGADPAK	HIVEP1	141	P15822
QDRRWTNPDGTTSKI	TNS2	1351	Q63HR2
QLAWKATDRFRGPDA	AVPR2	96	P30518
AEWDDLKQLRSSRGG	LRP4	1821	O75096
AQETWEDKRRGLTLP	ART5	71	Q96L15
DEASWRRHQQSPGSK	NECAB3	351	Q96P71